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Diets that promote muscle growth

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https://www.readbyqxmd.com/read/28924423/vegan-diets-practical-advice-for-athletes-and-exercisers
#1
REVIEW
David Rogerson
With the growth of social media as a platform to share information, veganism is becoming more visible, and could be becoming more accepted in sports and in the health and fitness industry. However, to date, there appears to be a lack of literature that discusses how to manage vegan diets for athletic purposes. This article attempted to review literature in order to provide recommendations for how to construct a vegan diet for athletes and exercisers. While little data could be found in the sports nutrition literature specifically, it was revealed elsewhere that veganism creates challenges that need to be accounted for when designing a nutritious diet...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28920404/effects-of-zearalenone-on-the-localization-and-expression-of-the-growth-hormone-receptor-gene-in-the-uteri-of-post-weaning-piglets
#2
Min Zhou, LiJie Yang, Weiren Yang, Libo Huang, Xuemei Zhou, Shuzhen Jiang, Zaibin Yang
Objective: In this study, we investigated the adverse effects of dietary zearalenone (ZEA) (0.5 to 1.5 mg•kg-1 diet) on the localization and expression of the growth hormone receptor (GHR) in the uteri of post-weaning gilts and explored another mechanism of the reproductive toxicity of ZEA on piglets. Methods: A total of forty healthy piglets (Duroc × Landrace × Large White) aged 28 d were selected for study. Piglets were transferred to single cages after 10 days' adaptation on an obstetric table...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28912874/dietary-vitamin-b6-modulates-the-gene-expression-of-myokines-nrf2-related-factors-myogenin-and-hsp60-in-the-skeletal-muscle-of-rats
#3
Sofya Suidasari, Shinji Uragami, Noriyuki Yanaka, Norihisa Kato
Previous studies have suggested that vitamin B6 is an ergogenic factor. However, the role of dietary vitamin B6 in skeletal muscle has not been widely researched. The aim of the present study was to investigate the effects of dietary vitamin B6 on the gene expression of 19 myokines, 14 nuclear factor erythroid 2-related factor 2 (Nrf2)-regulated factors, 8 myogenesis-related factors and 4 heat shock proteins (HSPs), which may serve important roles in skeletal muscles. Rats were fed a diet containing 1 (marginal vitamin B6 deficiency), 7 (recommended dietary level) or 35 mg/kg of pyridoxine (PN) HCl/ for 6 weeks...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28815354/nf-e2-related-factor-2-suppresses-intestinal-fibrosis-by-inhibiting-reactive-oxygen-species-dependent-tgf-%C3%AE-1-smads-pathway
#4
Yadi Guan, Yue Tan, Weiyu Liu, Jun Yang, Dongxu Wang, Di Pan, Yan Sun, Changqing Zheng
BACKGROUND AND AIMS: This study aimed to evaluate the antifibrotic effects of NF-E2-Related Factor 2 (Nrf2) on intestinal fibrosis. Intestinal fibrosis is a common complication of Crohn's disease; however, its mechanism of intestinal fibrosis is largely unclear. METHODS: BALB/c mice received 2,4,6-trinitrobenzene sulfonic acid weekly via intrarectal injections to induce chronic fibrotic colitis. They also diet containing received 1% (w/w) tert-butylhydroquinone (tBHQ), which is an agonist of Nrf2...
August 16, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28798193/the-role-of-vascular-endothelial-growth-factor-b-in-metabolic-homoeostasis-current-evidence
#5
REVIEW
Mohammad Ishraq Zafar, Juan Zheng, Wen Kong, Xiaofeng Ye, Luoning Gou, Anita Regmi, Lu-Lu Chen
It has been shown that adipose tissue and skeletal muscles in lean individuals respond to meal-induced hyperinsulinemia by increase in perfusion, the effect not observed in patients with metabolic syndrome. In conditions of hyperglycaemia and hypertriglyceridemia, this insufficient vascularization leads to the liberation of reactive oxygen species (ROS), and disruption of nitric oxide (NO) synthesis and endothelial signalling responsible for the uptake of circulating fatty acids (FAs), whose accumulation in skeletal muscles and adipose tissue is widely associated with the impairment of insulin signalling...
August 31, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28701315/effect-of-endurance-training-and-branched-chain-amino-acids-on-the-signaling-for-muscle-protein-synthesis-in-ckd-model-rats-fed-a-low-protein-diet
#6
Takuya Yoshida, Sachika Kakizawa, Yuri Totsuka, Miho Sugimoto, Shinji Miura, Hiromichi Kumagai
A low-protein diet (LPD) protects against the progression of renal injury in patients with chronic kidney disease (CKD). However, LPD may accelerate muscle wasting in these patients. Both exercise and branched chain amino acids (BCAA) are known to increase muscle protein synthesis by activating the mammalian target of rapamycin (mTOR) pathway. The aim of this study is to investigate whether endurance exercise and BCAA play a role for increasing muscle protein synthesis in LPD-fed CKD (5/6 nephrectomized) rats...
July 12, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28623008/yucca-schidigera-can-promote-rabbit-growth-fecundity-affect-the-release-of-hormones-in-vivo-and-in-vitro-induce-pathological-changes-in-liver-and-reduce-ovarian-resistance-to-benzene
#7
Martina Földešiová, Andrej Baláži, Ľubica Chrastinová, Juraj Pivko, Jan Kotwica, Abdel Halim Harrath, Peter Chrenek, Alexander V Sirotkin
This study evaluated the effect of Yucca schidigera (YS) extract on the physiological, reproductive, and endocrine indexes of New Zealand White rabbit does. Six-week-old rabbit does were fed a standard diet (control group) or a diet enriched with 5 or 20g of Y powder extract per 100-kg feed mixture for 350days. The does were artificially inseminated after induction of superovulation. Weight gain; conception and kindling rate; viability of pups and mothers; histopathological state of liver and muscle; plasma levels of progesterone (P4), oxytocin (OT), and prostaglandin F (PGF); and the release of P4, insulin-like growth factor I (IGF-I), OT, and PGF by isolated ovarian fragments and their response to the addition of benzene were analyzed...
June 10, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28621563/reduced-mastication-impairs-memory-function
#8
Y Fukushima-Nakayama, Takehito Ono, M Hayashi, M Inoue, H Wake, Takashi Ono, T Nakashima
Mastication is an indispensable oral function related to physical, mental, and social health throughout life. The elderly tend to have a masticatory dysfunction due to tooth loss and fragility in the masticatory muscles with aging, potentially resulting in impaired cognitive function. Masticatory stimulation has influence on the development of the central nervous system (CNS) as well as the growth of maxillofacial tissue in children. Although the relationship between mastication and cognitive function is potentially important in the growth period, the cellular and molecular mechanisms have not been sufficiently elucidated...
August 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28607005/opa1-deficiency-promotes-secretion-of-fgf21-from-muscle-that-prevents-obesity-and-insulin-resistance
#9
Renata Oliveira Pereira, Satya M Tadinada, Frederick M Zasadny, Karen Jesus Oliveira, Karla Maria Pereira Pires, Angela Olvera, Jennifer Jeffers, Rhonda Souvenir, Rose Mcglauflin, Alec Seei, Trevor Funari, Hiromi Sesaki, Matthew J Potthoff, Christopher M Adams, Ethan J Anderson, E Dale Abel
Mitochondrial dynamics is a conserved process by which mitochondria undergo repeated cycles of fusion and fission, leading to exchange of mitochondrial genetic content, ions, metabolites, and proteins. Here, we examine the role of the mitochondrial fusion protein optic atrophy 1 (OPA1) in differentiated skeletal muscle by reducing OPA1 gene expression in an inducible manner. OPA1 deficiency in young mice results in non-lethal progressive mitochondrial dysfunction and loss of muscle mass. Mutant mice are resistant to age- and diet-induced weight gain and insulin resistance, by mechanisms that involve activation of ER stress and secretion of fibroblast growth factor 21 (FGF21) from skeletal muscle, resulting in increased metabolic rates and improved whole-body insulin sensitivity...
July 14, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28579299/sglt2-inhibition-by-empagliflozin-promotes-fat-utilization-and-browning-and-attenuates-inflammation-and-insulin-resistance-by-polarizing-m2-macrophages-in-diet-induced-obese-mice
#10
Liang Xu, Naoto Nagata, Mayumi Nagashimada, Fen Zhuge, Yinhua Ni, Guanliang Chen, Eric Mayoux, Shuichi Kaneko, Tsuguhito Ota
Sodium-glucose cotransporter (SGLT) 2 inhibitors increase urinary glucose excretion (UGE), leading to blood glucose reductions and weight loss. However, the impacts of SGLT2 inhibition on energy homeostasis and obesity-induced insulin resistance are less well known. Here, we show that empagliflozin, a SGLT2 inhibitor, enhanced energy expenditure and attenuated inflammation and insulin resistance in high-fat-diet-induced obese (DIO) mice. C57BL/6J mice were pair-fed a high-fat diet (HFD) or a HFD with empagliflozin for 16weeks...
June 2017: EBioMedicine
https://www.readbyqxmd.com/read/28494385/l-leucine-dietary-supplementation-modulates-muscle-protein-degradation-and-increases-pro-inflammatory-cytokines-in-tumour-bearing-rats
#11
Bread Cruz, André Oliveira, Maria Cristina Cintra Gomes-Marcondes
Cancer cachexia is characterised by involuntary weight loss associated with systemic inflammation and metabolic changes. Studies aimed at maintaining lean body mass in cachectic tumour-bearing hosts have made important contributions reducing the number of deaths and improving the quality of life. In recent years, leucine has demonstrated effective action in maintaining lean body mass by decreasing muscle protein degradation. Currently, there is a growing need to understand how leucine stimulates protein synthesis and acts protectively in a cachectic organism...
May 8, 2017: Cytokine
https://www.readbyqxmd.com/read/28461507/evolutionarily-conserved-trh-neuropeptide-pathway-regulates-growth-in-caenorhabditis-elegans
#12
Elien Van Sinay, Olivier Mirabeau, Geert Depuydt, Matthias Boris Van Hiel, Katleen Peymen, Jan Watteyne, Sven Zels, Liliane Schoofs, Isabel Beets
In vertebrates thyrotropin-releasing hormone (TRH) is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. However, a functional equivalent in protostomian animals remains unknown, although TRH receptors are conserved in proto- and deuterostomians. Here we identify a TRH-like neuropeptide precursor in Caenorhabditis elegans that belongs to a bilaterian family of TRH precursors. Using CRISPR/Cas9 and RNAi reverse genetics, we show that TRH-like neuropeptides, through the activation of their receptor TRHR-1, promote growth in Celegans TRH-like peptides from pharyngeal motor neurons are required for normal body size, and knockdown of their receptor in pharyngeal muscle cells reduces growth...
May 16, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28367770/effects-of-training-distance-on-feed-intake-growth-body-condition-and-muscle-glycogen-content-in-young-standardbred-horses-fed-a-forage-only-diet
#13
S Ringmark, T Revold, A Jansson
This study examined feed intake, growth, body condition, muscle glycogen content and nutrition-related health in 16 Standardbred horses fed a high-energy, forage-only diet ad libitum and allocated to either a control training programme (C-group) or a training programme with the high-intensity training distance reduced by 30% (R-group), from January as 2-year olds until December as 3-year olds. Feed intake was recorded on 10 occasions during 3 consecutive days. Body weight was recorded once in a week and height, body condition score (BCS), rump fat thickness and thickness of the m...
April 3, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28356434/the-growth-promoting-effect-of-dietary-nucleotides-in-fish-is-associated-with-an-intestinal-microbiota-mediated-reduction-in-energy-expenditure
#14
Xiaoze Guo, Chao Ran, Zhen Zhang, Suxu He, Min Jin, Zhigang Zhou
Background: Nucleotides have been used as functional nutrients to improve the growth and health of animals, including fish. The mechanism involved in the growth-promotion effect of nucleotides is still unclear.Objective: We investigated the bioenergetic mechanism underlying the growth-promotion effect of nucleotides in zebrafish and the associated roles played by the intestinal microbiota.Methods: Larval zebrafish were fed a control or a 0.1% mixed nucleotides-supplemented diet for 2 wk. Standard metabolic rate, the minimal rate of energy expenditure by animals at rest, was evaluated by oxygen consumption with the use of a respirometer...
May 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28217832/gestational-protein-restriction-study-of-the-probable-effects-on-cardiac-muscle-structure-and-function-in-adult-rats
#15
Mona G Amer, Nader M Mohamed, Aly A M Shaalan
Intrauterine growth restriction (IUGR) has been linked to heart disease in adulthood. This study aimed to examine the effect of gestational protein restriction during fetal and early postnatal life on the cardiac muscle structure and function in adult offspring. Pregnant female rats were randomly divided into two dietary groups: normal-protein diet (NP) and low-protein diet (LP). Fifteen male offspring from each group were included in the study. Offspring body weights were recorded at birth and monthly from weaning until 24 weeks of age while systolic blood pressure was measured weekly...
February 20, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28186980/diet-induced-obesity-links-to-er-positive-breast-cancer-progression-via-lpa-pkd-1-cd36-signaling-mediated-microvascular-remodeling
#16
Liuyi Dong, Ye Yuan, Cynthia Opansky, Yiliang Chen, Irene Aguilera-Barrantes, Shiyong Wu, Rong Yuan, Qi Cao, Yee Chung Cheng, Daisy Sahoo, Roy L Silverstein, Bin Ren
Obesity increases cancer risk including breast cancer (BC). However, the direct regulatory mechanisms by which obesity promotes BC progression remain largely unknown. We show that lysophosphatidic acid/protein kinase D1 (LPA/PKD-1)-CD36 signaling is a bona fide breast cancer promoter via stimulating microvascular remodeling in chronic diet-induced obesity (DIO). We observed that the growth of an estrogen receptor (ER) positive breast cancer was markedly increased when compared to the lean control, and specifically accompanied by increased microvascular remodeling in a syngeneic BC model in female DIO mice...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28115977/efficacy-of-a-novel-formulation-of-l-carnitine-creatine-and-leucine-on-lean-body-mass-and-functional-muscle-strength-in-healthy-older-adults-a-randomized-double-blind-placebo-controlled-study
#17
Malkanthi Evans, Najla Guthrie, John Pezzullo, Toran Sanli, Roger A Fielding, Aouatef Bellamine
BACKGROUND: Progressive decline in skeletal muscle mass and function are growing concerns in an aging population. Diet and physical activity are important for muscle maintenance but these requirements are not always met. This highlights the potential for nutritional supplementation. As a primary objective, we sought to assess the effect of a novel combination of L-Carnitine, creatine and leucine on muscle mass and performance in older subjects. METHOD: Forty-two healthy older adults aged 55-70 years were randomized to receive either a novel L-Carnitine (1500 mg), L-leucine (2000 mg), creatine (3000 mg), Vitamin D3 (10 μg) (L-Carnitine-combination) product (n = 14), L-Carnitine (1500 mg) (n = 14), or a placebo (n = 14) for eight weeks...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28106759/sex-specific-muscular-maturation-responses-following-prenatal-exposure-to-methylation-related-micronutrients-in-pigs
#18
Michael Oster, Nares Trakooljul, Henry Reyer, Annette Zeyner, Eduard Muráni, Siriluck Ponsuksili, Klaus Wimmers
Supplementation of micronutrients involved in DNA methylation, particularly during pregnancy, is recommended because of its impacts on human health, but further evidence is needed regarding the effects of over-supplementation and differences between sexes. Here, a porcine model was used to assess effects of maternal supplementation with one-carbon-cycle compounds during prenatal and postnatal stages on offspring muscle development. Sows received either a standard diet (CON) or a standard diet supplemented with folate, B6, B12, methionine, choline, and zinc (MET) throughout gestation...
January 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28074127/transfer-of-%C3%AE-hydroxy-%C3%AE-methylbutyrate-from-sows-to-their-offspring-and-its-impact-on-muscle-fiber-type-transformation-and-performance-in-pigs
#19
Haifeng Wan, Jiatao Zhu, Caimei Wu, Pan Zhou, Yong Shen, Yan Lin, Shengyu Xu, Lianqiang Che, Bin Feng, Jian Li, Zhengfeng Fang, De Wu
BACKGROUND: Previous studies suggested that supplementation of lactating sows with β-hydroxy-β-methylbutyrate (HMB) could improve the performance of weaning pigs, but there were little information in the muscle fiber type transformation of the offspring and the subsequent performance in pigs from weaning through finishing in response to maternal HMB consumption. The purpose of this study was to determine the effect of supplementing lactating sows with HMB on skeletal muscle fiber type transformation and growth of the offspring during d 28 and 180 after birth...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/27933336/shp-1-activation-inhibits-vascular-smooth-muscle-cell-proliferation-and-intimal-hyperplasia-in-a-rodent-model-of-insulin-resistance-and-diabetes
#20
Weier Qi, Qian Li, Chong Wee Liew, Christian Rask-Madsen, Samuel M Lockhart, Lars Melholt Rasmussen, Yu Xia, Xuanchun Wang, Mogher Khamaisi, Kevin Croce, George L King
AIMS/HYPOTHESIS: Accelerated migration and proliferation of vascular smooth muscle cells (VSMCs) enhances arterial restenosis after angioplasty in insulin resistance and diabetes. Elevation of Src homology 2-containing protein tyrosine phosphatase 1 (SHP-1) induces apoptosis in the microvasculature. However, the role of SHP-1 in intimal hyperplasia and restenosis has not been clarified in insulin resistance and diabetes. METHODS: We used a femoral artery wire injury mouse model, rodent models with insulin resistance and diabetes, and patients with type 2 diabetes...
March 2017: Diabetologia
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