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patellar tumor

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https://www.readbyqxmd.com/read/27692557/the-development-of-a-xenograft-derived-scaffold-for-tendon-and-ligament-reconstruction-using-a-decellularization-and-oxidation-protocol
#1
Thorsten M Seyler, Daniel N Bracey, Johannes F Plate, Mark O Lively, Sandeep Mannava, Thomas L Smith, Justin M Saul, Gary G Poehling, Mark E Van Dyke, Patrick W Whitlock
PURPOSE: To evaluate the biological, immunological, and biomechanical properties of a scaffold derived by architectural modification of a fresh-frozen porcine patella tendon using a decellularization protocol that combines physical, chemical, and enzymatic modalities. METHODS: Porcine patellar tendons were processed using a decellularization and oxidation protocol that combines physical, chemical, and enzymatic modalities. Scaffolds (n = 88) were compared with native tendons (n = 70) using histologic, structural (scanning electron microscopy, porosimetry, and tensile testing), biochemical (mass spectrometry, peracetic acid reduction, DNA quantification, alpha-galactosidase [α-gal] content), as well as in vitro immunologic (cytocompatibility, cytokine induction) and in vivo immunologic nonhuman primate analyses...
September 27, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27313738/giant-cell-tumor-of-the-patella-with-a-secondary-aneurysmal-bone-cyst-a-case-report
#2
Mingzhi Song, Wei Dai, Ran Sun, Hongfeng Liang, Bingwu Liu, Yuxuan Wu, Kai Ma, Ming Lu
The substance of the patella is an uncommon location for tumor occurrence and development. The present study reports a case of giant cell tumor (GCT) of the patella, combined with an aneurysmal bone cyst (ABC). To the best of our knowledge, this is the second report of GCT with ABC published in English. GCT is the most common type of benign tumor. Secondary ABC is frequently associated with GCT, but this symbiotic tumor rarely occurs in the patella. A 27-year-old male patient was examined at the outpatient clinic, and clinicopathological characteristics of the tumor were observed...
June 2016: Oncology Letters
https://www.readbyqxmd.com/read/27299076/a-rare-case-report-of-patellar-osteochondroma
#3
Abhinav S Bhatnagar, Kaushal Malhan, Sonu Mehta
INTRODUCTION: Osteochondroma (OC) is the most common benign tumor of the skeleton. However, patellar OC is very rare. Only five case reports have been published yet and only 1 after the year 1972. OCs grow during childhood through adolescence, but usually growing ends when the epiphyseal plates close. In an adult, the growth of an OC suggests the diagnosis of malignant transformation to a chondrosarcoma. However, enlargement of a patellar OC reported as benign after skeletal maturity is present in literature...
July 2015: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/27217817/tumors-of-the-patella-the-experience-of-institute-of-orthopedics-and-traumatology-at-university-of-s%C3%A3-o-paulo-brazil
#4
André Mathias Baptista, Sylvio Cesar Sargentini, Juan Pablo Zumárraga, André Ferrari De França Camargo, Olavo Pires De Camargo
OBJECTIVE: To obtain epidemiological data from the tumors of the patella diagnosed and treated at the Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da Universidade de São Paulo (IOT-HC-FMUSP) between 1998 and 2015. METHODS: Series of cases with retrospective evaluation of patients diagnosed with tumors located in the patella. The data was obtained from the records and patients' charts at the Department of Pathology of IOT-HC-FMUSP. RESULTS: A total of 2220 medical records from patients with anatomopathological reports were included in the study...
May 2016: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/27123148/arthroscopic-excision-of-giant-cell-tumor-of-the-tendon-sheath-in-the-knee-mimicking-patellar-tendinopathy-a-case-report
#5
Kai Gao, Jiwu Chen, Shiyi Chen, Yunxia Li
Giant cell tumor of the tendon sheath (GCTTS) predominantly occurs in the tendon sheaths of the hand, but rarely in those of the knee. The current study reports the case of a 36-year-old male patient presenting with anterior knee pain. The patient was ultimately diagnosed with GCTTS in the knee mimicking patellar tendinopathy. To the best of our knowledge, this is the first case of its kind. Magnetic resonance imaging revealed a well-defined oval intra-articular lesion located at the proximal segment of the infrapatellar fat pad...
May 2016: Oncology Letters
https://www.readbyqxmd.com/read/27078131/distal-femoral-replacement-for-acute-distal-femoral-fractures-in-elderly-patients
#6
Clayton C Bettin, John C Weinlein, Patrick C Toy, Robert K Heck
OBJECTIVES: To evaluate outcomes and complications using cemented modular distal femoral replacement in elderly patients with distal femoral fractures. DESIGN: Retrospective chart review, case series. SETTING: A Level 1 and Level 2 trauma center, both tertiary referral hospitals. PATIENTS/PARTICIPANTS: Eighteen patients older than 60 years (average age 77 years) who had cemented distal femoral replacement for distal femoral fractures (comminuted, intraarticular, osteoporotic, arthritic) between 2005 and 2013...
September 2016: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/27053582/patellar-resurfacing-does-it-affect-outcomes-of-distal-femoral-replacement-after-distal-femoral-resection
#7
Mauricio Etchebehere, Patrick P Lin, Justin E Bird, Robert L Satcher, Bryan S Moon, Jun Yu, Liang Li, Valerae O Lewis
BACKGROUND: Patellar resurfacing after routine arthroplasty remains controversial. Few studies have specifically examined the effect of patellar resurfacing on outcomes after resection of the distal part of the femur and reconstruction with a megaprosthesis. Our objective was to compare the outcomes of megaprosthesis reconstructions of the distal part of the femur with and without patellar resurfacing after resection of a distal femoral tumor. METHODS: We retrospectively reviewed the clinical records of patients with a femoral tumor who underwent resection of the distal part of the femur and endoprosthetic reconstruction between 1993 and 2013...
April 6, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/26714400/-tissue-flap-repair-strategy-for-severe-defects-of-skin-and-soft-tissue-around-the-knee-joints
#8
Yuming Shen, Chunxu Ma, Xiaohua Hu, Cheng Wang, Cong Zhang
OBJECTIVE: To explore selection and method of tissue flaps for the repair of severe defects of skin and soft tissue around the knee joints. METHODS: Fifty-four patients with wounds around the knee joints, all accompanied by exposure or necrosis of tendon or bone and exposure of prosthesis, were hospitalized in our burn center from June 2008 to December 2014. Five of them were with knee joint injury. After thorough debridement or tumor resection, the wound area ranged from 5 cm × 5 cm to 46 cm × 22 cm...
October 2015: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/26640752/bone-patellar-tendon-bone-allograft-reconstruction-for-peri-patellar-tendon-sarcomas-case-series
#9
Jungo Imanishi, Damien Grinsell, Peter F M Choong
INTRODUCTION: Reconstruction after wide resection for a sarcoma involving the knee extensor mechanism is challenging even if the tumor is small. CASE DESCRIPTION: We report on four consecutive peri-patellar tendon sarcomas treated similarly at a single institution. Histological diagnoses were synovial sarcoma (two cases), clear cell sarcoma and extraskeletal Ewing's sarcoma (one case each). Follow-up periods after surgery were 18-67 months. All cases underwent pre-operative radiotherapy and subsequent surgery...
2015: SpringerPlus
https://www.readbyqxmd.com/read/26601638/patellar-height-decreasing-after-distal-femur-endoprosthesis-reconstruction-does-not-affect-functional-outcome
#10
Mauricio Etchebehere, Patrick P Lin, Bryan S Moon, Jun Yu, Liang Li, Valerae O Lewis
INTRODUCTION: The patellar height can influence extensor mechanism and the knee function. Thus, during knee arthroplasty, the surgeon seeks to maintain the correct patellar height. However, it is more difficult to define and maintain the correct patella height in megaprosthesis reconstructions after tumor resections. The objective of this study was to evaluate patellar height after distal femur endoprosthesis reconstruction and its association to knee function. METHODS: This retrospective analysis included 108 patients who underwent distal femur resections and endoprosthesis reconstruction...
February 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/26373929/the-differential-effects-of-leukocyte-containing-and-pure-platelet-rich-plasma-prp-on-tendon-stem-progenitor-cells-implications-of-prp-application-for-the-clinical-treatment-of-tendon-injuries
#11
Yiqin Zhou, Jianying Zhang, Haishan Wu, MaCalus V Hogan, James H-C Wang
INTRODUCTION: Platelet-rich plasma (PRP) is widely used to treat tendon injuries in clinics. These PRP preparations often contain white blood cells or leukocytes, and the precise cellular effects of leukocyte-rich PRP (L-PRP) on tendons are not well defined. Therefore, in this study, we determined the effects of L-PRP on tendon stem/progenitor cells (TSCs), which play a key role in tendon homeostasis and repair. METHODS: TSCs isolated from the patellar tendons of rabbits were treated with L-PRP or P-PRP (pure PRP without leukocytes) in vitro, followed by measuring cell proliferation, stem cell marker expression, inflammatory gene expression, and anabolic and catabolic protein expression by using immunostaining, quantitative real-time polymerase chain reaction, Western blot, and enzyme-linked immunosorbent assay, respectively...
September 15, 2015: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/26224822/function-of-the-extensor-mechanism-of-the-knee-after-using-the-patellar-loop-technique-to-reconstruct-the-patellar-tendon-when-replacing-the-proximal-tibia-for-tumour
#12
H Pilge, B M Holzapfel, H Rechl, P M Prodinger, R Lampe, U Saur, R Eisenhart-Rothe, H Gollwitzer
The aim of this study was to analyse the gait pattern, muscle force and functional outcome of patients who had undergone replacement of the proximal tibia for tumour and alloplastic reconstruction of the extensor mechanism using the patellar-loop technique. Between February 1998 and December 2009, we carried out wide local excision of a primary sarcoma of the proximal tibia, proximal tibial replacement and reconstruction of the extensor mechanism using the patellar-loop technique in 18 patients. Of these, nine were available for evaluation after a mean of 11...
August 2015: Bone & Joint Journal
https://www.readbyqxmd.com/read/26193207/proximal-tibial-osteosarcoma-in-young-patients-early-diagnosis-modular-reconstruction
#13
Răzvan Ene, Ruxandra Diana Sinescu, Patricia Ene, Dan Popescu, Monica Mihaela Cîrstoiu, Florin Cătălin Cîrstoiu
Osteosarcoma is the most common bone tumor that occurs in children and young adults with prevalence of teenage. There can be identified many subtypes of osteosarcoma by how they look on X-rays and under the microscope. Osteosarcoma can be classified as high-grade, intermediate grade, or low-grade. This has a significant prognostic value of tumor development suggesting the growth rate and the potential for expansion. Between 2009-2013, in the Department of Orthopedics and Traumatology, University Emergency Hospital of Bucharest, Romania, were treated seven cases of osteosarcoma of the proximal third of the tibia in young, early-diagnosed cases without metastasis...
2015: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/26165715/-a-patellar-giant-cell-tumor-with-soft-tissue-involvement-an-alternative-treatment-method-and-review-of-the-literature
#14
REVIEW
Gökay Görmeli, Cemile Ayşe Görmeli, Zeynep Maraş Özdemir, Reşit Sevimli, Nusret Akpolat
In this article, we report a case of a giant-cell tumor of the patella which occurred in an atypical location with soft tissue involvement, which makes our case clinically and radiologically unique. A 24-year-old patient was admitted to our clinic with a complaint of anterior knee pain. Radiological examination and percutaneous fine needle biopsy showed a diagnosis of giant-cell tumor of the patella. The patient underwent patellectomy with en-bloc resection of the lesion with totally involved soft tissue components and the extensor mechanism was reconstructed with two Achilles allografts...
2015: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/26115022/hemorrhagic-intramedullary-solitary-fibrous-tumor-of-the-conus-medullaris-case-report
#15
Corey T Walker, Chiazo S Amene, Jeffrey S Pannell, David R Santiago-Dieppa, Robert C Rennert, Lawrence A Hansen, Alexander A Khalessi
The differential diagnosis of spinal tumors is guided by anatomical location and imaging characteristics. Diagnosis of rare tumors is made challenging by abnormal features. The authors present the case of a 47-year-old woman who presented with progressive subacute right lower-extremity weakness and numbness of the right thigh. Physical examination further revealed an extensor response to plantar reflex on the right and hyporeflexia of the right Achilles and patellar reflexes. Magnetic resonance imaging of the lumbar spine demonstrated an 8-mm intramedullary exophytic nodule protruding into a hematoma within the conus medullaris...
October 2015: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/26003215/a-new-technique-using-mesh-for-extensor-reconstruction-after-proximal-tibial-resection
#16
Jiro Ichikawa, Seiichi Matsumoto, Takashi Shimoji, Keisuke Ae, Taisuke Tanizawa, Tabu Gokita
BACKGROUND: Proximal tibial reconstruction following wide resection in both malignant and benign tumors presents difficulties mainly due to both patellar tendon reconstruction and high risk of infection. The purpose of this study is to determine the efficacy of a new technique using a mesh for extensor reconstruction. METHODS: We retrospectively reviewed nine consecutive patients who underwent resection of the proximal tibia with prosthetic reconstruction and reconstruction of the extensor using a mesh between 2009 and 2012...
December 2015: Knee
https://www.readbyqxmd.com/read/25992888/somatic-antigens-of-tropical-liver-flukes-ameliorate-collagen-induced-arthritis-in-wistar-rats
#17
Yasir Akhtar Khan, Sadiq Umar, Syed M A Abidi
Parasitic helminths polarize immune response of their vertebrate hosts towards anti-inflammatory Th2 type and therefore it is hypothesized that they may suppress the inflammatory conditions in autoimmune disorders. The present study was undertaken to investigate in vivo immunomodulatory and therapeutic potential of somatic antigens (Ag) of liver infecting digenetic trematodes [Fasciola gigantica (Fg) and Gigantocotyle explanatum (Ge)] in collagen-induced arthritic (CIA) Wistar rats. The CIA rats were administered subcutaneously with different doses (50 μg, 100 μg and 150 μg) of somatic antigens of Fg and Ge, daily for 21 days, the time period required to establish infection in natural host (Bubalus bubalis)...
2015: PloS One
https://www.readbyqxmd.com/read/25906772/primary-tumors-of-the-patella
#18
REVIEW
Mingzhi Song, Zhen Zhang, Yuxuan Wu, Kai Ma, Ming Lu
The patella is an uncommon location for cancerous occurrence and development. The majority of tumors of the patella are benign, with a significant incidence of giant cell tumors and chondroblastoma. With the development of modern diagnostic technologies, there appear however many other histological types which raise challenges of diagnosis and treatment. In this article, we review the reported histological types of primary patellar tumors. Specifically, epidemiology, symptomatology, imageology, histopathology, and treatment options for these histological lesions will be discussed, respectively...
2015: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/25469296/giant-cell-tumor-of-the-patella-an-uncommon-cause-of-anterior-knee-pain
#19
Tatsuya Shibata, Jun Nishio, Taiki Matsunaga, Mikiko Aoki, Hiroshi Iwasaki, Masatoshi Naito
The patella is a rare site for the development of primary tumors. This is the case report of a giant cell tumor (GCT) occurring in the patella in a 25-year-old woman. The patient presented with a 1-year history of occasional right anterior knee pain. The radiological characteristics suggested a benign condition. The intraoperative pathological diagnosis was GCT of the bone. The lesion was treated by radical curettage with adjuvant therapy comprising phenol and ethanol and injection of calcium phosphate cement...
January 2015: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/25360180/giant-cell-tumor-of-the-tendon-sheath-extending-around-the-patellar-tendon-and-invading-the-knee-joint-and-tibia-a-case-report
#20
Tsutomu Akahane, Naoya Mori, Kazushige Yoshida
The current report presents the case of a 41-year-old male exhibiting a giant cell tumor of the tendon sheath (GCT-TS) arising from the patellar tendon sheath. Plain radiography and magnetic resonance imaging revealed a well-localized mass that wrapped around the patellar tendon, and extended from the subcutis into the infrapatellar fat pad and tibia. Following histopathological determination of the diagnosis, a piecemeal resection was performed. Nodular-type GCT-TS occurs less frequently in large joints compared with the small joints of the fingers and toes...
December 2014: Oncology Letters
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