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https://www.readbyqxmd.com/read/28105775/concordance-correlation-coefficients-estimated-by-generalized-estimating-equations-and-variance-components-for-longitudinal-repeated-measurements
#1
Miao-Yu Tsai
The concordance correlation coefficient (CCC) is a commonly accepted measure of agreement between two observers for continuous responses. This paper proposes a generalized estimating equations (GEE) approach allowing dependency between repeated measurements over time to assess intra-agreement for each observer and inter- and total agreement among multiple observers simultaneously. Furthermore, the indices of intra-, inter-, and total agreement through variance components (VC) from an extended three-way linear mixed model (LMM) are also developed with consideration of the correlation structure of longitudinal repeated measurements...
January 20, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28099589/which-coronary-lesions-are-more-prone-to-cause-acute-myocardial-infarction
#2
Taner Sen, Mehmet Ali Astarcioglu, Osman Beton, Lale Dinc Asarcikli, Celal Kilit
Background: According to common belief, most myocardial infarctions (MIs) are due to the rupture of nonsevere, vulnerable plaques with < 70% obstruction. Data from recent trials challenge this belief, suggesting that the risk of coronary occlusion is, in fact, much higher after severe stenosis. The aim of this study was to investigate whether or not acute ST-elevation MIs result from high-grade stenoses by evaluating the presence of coronary collateral circulation (CCC). Methods: We retrospectively included 207 consecutive patients who had undergone primary percutaneous coronary intervention for acute ST-elevation MI...
January 16, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28090765/aggregation-kinetics-of-diesel-soot-nanoparticles-in-wet-environments
#3
Chengyu Chen, Weilin Huang
Soot produced during incomplete combustion consists mainly of carbonaceous nanoparticles (NPs) with severe adverse environmental and health effects, and its environmental fate and transport are largely controlled by aggregation. In this study, we examined the aggregation behavior for diesel soot NPs under aqueous condition in an effort to elucidate the fundamental processes that govern soot particle-particle interactions in wet environments such as rain droplets or surface aquatic systems. The influence of electrolytes and aqueous pH on colloidal stability of these NPs was investigated by measuring their aggregation kinetics in different aqueous solution chemistries...
January 16, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28088800/repeatability-and-reproducibility-of-foveal-avascular-zone-area-measurements-using-angioplex-spectral-domain-optical-coherence-tomography-angiography-in-healthy-subjects
#4
Jiaxian Guo, Xiangjun She, Xiaoying Liu, Xiaodong Sun
PURPOSE: The aim of this study was to evaluate the repeatability and reproducibility of foveal avascular zone (FAZ) area measurements using AngioPlex spectral domain optical coherence tomography (OCT) angiography in normal subjects. METHODS: Twenty-two healthy subjects (25 eyes) underwent FAZ area measurements with AngioPlex OCT. Each volunteer was separately examined 3 consecutive times by the 2 experienced observers. The FAZ area was measured using ImageJ software...
January 14, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28077098/validity-of-gestational-age-estimates-by-last-menstrual-period-and-neonatal-examination-compared-to-ultrasound-in-vietnam
#5
Nicholas P Deputy, Phuong H Nguyen, Hoa Pham, Son Nguyen, Lynnette Neufeld, Reynaldo Martorell, Usha Ramakrishnan
BACKGROUND: Accurate estimation of gestational age is important for both clinical and public health purposes. Estimates of gestational age using fetal ultrasound measurements are considered most accurate but are frequently unavailable in low- and middle-income countries. The objective of this study was to assess the validity of last menstrual period and Farr neonatal examination estimates of gestational age, compared to ultrasound estimates, in a large cohort of women in Vietnam. METHODS: Data for this analysis come from a randomized, placebo-controlled micronutrient supplementation trial in Vietnam...
January 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28071006/sensory-qualities-of-pastry-products-enriched-with-dietary-fiber-and-polyphenolic-substances
#6
Patrycja Komolka, Danuta Górecka, Krystyna Szymandera-Buszka, Anna Jędrusek-Golińska, Krzysztof Dziedzic, Katarzyna Waszkowiak
BACKGROUND: Growing consumer demand for products with pro-health properties is forcing food manufacturers to introduce new food items onto the market, which will not only possess such health-enhancing properties but will also compete on the grounds of sensory attributes - taste, flavour, texture etc. METHODS: The aim was to evaluate these sensory attributes of pastry products enhanced with biologically active compounds, such as inulin, buckwheat hull and buckwheat flour...
April 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28070671/place-of-death-of-children-with-complex-chronic-conditions-cross-national-study-of-11-countries
#7
Cecilia Håkanson, Joakim Öhlén, Ulrika Kreicbergs, Marylou Cardenas-Turanzas, Donna M Wilson, Martin Loucka, Sandra Frache, Lucia Giovannetti, Wayne Naylor, YongJoo Rhee, Miguel Ruiz Ramos, Joan Teno, Kim Beernaert, Luc Deliens, Dirk Houttekier, Joachim Cohen
: Cross-national understanding of place of death is crucial for health service systems for their provision of efficient and equal access to paediatric palliative care. The objectives of this population-level study were to examine where children with complex chronic conditions (CCC) die and to investigate associations between places of death and sex, cause of death and country. The study used death certificate data of all deceased 1- to 17-year-old children (n = 40,624) who died in 2008, in 11 European and non-European countries...
January 9, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28068468/aggregation-kinetics-and-self-assembly-mechanisms-of-graphene-quantum-dots-in-aqueous-solutions-cooperative-effects-of-ph-and-electrolytes
#8
Qingqing Li, Baoliang Chen, Baoshan Xing
The cooperative effects of pH and electrolytes on the aggregation of GQDs and the aggregate morphologies are characterized. Because GQDs have an average size of 9 nm with abundant O-functionalized edges, their suspension was very stable even in a high electrolyte concentration and low pH solution. Divalent cations (Mg2+ and Ca2+) exceled at aggregating the GQD nanoplates, while monovalent cations (Na+ and K+) did not disturb the stability. For Na+ and K+, positive linear correlations were observed between the critical coagulation concentration (CCC) and pH levels...
January 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28058813/outcomes-of-a-multi-community-hypertension-implementation-study-the-american-heart-association-s-check-change-control-program
#9
Monique L Anderson, Rachel Peragallo Urrutia, Emily C O'Brien, Nancy M Allen LaPointe, Alexander J Christian, Lisa A Kaltenbach, Laura E Webb, Angel M Alexander, Paramita Saha Chaudhuri, Juliana Crawford, Patrick Wayte, Eric D Peterson
: Single-site, intensive, community-based blood pressure (BP) intervention programs have led to BP improvements. The authors examined the American Heart Association's Check. Change. CONTROL: (CCC) program (4069 patients/18 cities) to determine whether BP interventions can effectively be scaled to multiple communities, using a simplified template and local customization. Effectiveness was evaluated at each site via site percent enrollment goals, participant engagement, and BP change from first to last measurement...
January 6, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28052593/panoramic-ultrasound-a-novel-and-valid-tool-for-monitoring-change-in-muscle-mass
#10
Jessica M Scott, David S Martin, Robert Ploutz-Snyder, Timothy Matz, Timothy Caine, Meghan Downs, Kyle Hackney, Roxanne Buxton, Jeffrey W Ryder, Lori Ploutz-Snyder
BACKGROUND: The strong link between reduced muscle mass and morbidity and mortality highlights the urgent need for simple techniques that can monitor change in skeletal muscle cross-sectional area (CSA). Our objective was to examine the validity of panoramic ultrasound to detect change in quadriceps and gastrocnemius size in comparison with magnetic resonance imaging (MRI) in subjects randomized to 70 days of bed rest (BR) with or without exercise. METHODS: Panoramic ultrasound and MRI images of the quadriceps and gastrocnemius muscles were acquired on the right leg of 27 subjects (26 male, 1 female; age: 34...
January 3, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28052064/validity-and-intra-observer-reliability-of-three-dimensional-scanning-compared-to-conventional-anthropometry-for-children-and-adolescents-from-a-population-based-cohort-study
#11
Fabian Glock, Mandy Vogel, Stephanie Naumann, Andreas Kuehnapfel, Markus Scholz, Andreas Hiemisch, Toralf Kirsten, Kristin Rieger, Antje Koerner, Markus Loeffler, Wieland Kiess
BackgroundConventional anthropometric measurements are time consuming and require well trained medical staff. To use three-dimensional whole body laser scanning in daily clinical work, validity and reliability have to be confirmed.MethodsWe compared a whole body laser scanner to conventional anthropometry in a group of 473 children and adolescents from the Leipzig Research Centre for Civilization Diseases (LIFE-Child). Concordance correlation coefficients (CCC) were calculated separately for sex, weight and age to assess validity...
January 4, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28049583/purification-of-semiconducting-single-walled-carbon-nanotubes-by-spiral-counter-current-chromatography
#12
Martha Knight, Rodrigo Lazo-Portugal, Saeyoung Nate Ahn, Steingrimur Stefansson
Over the last decade man-made carbon nanostructures have shown great promise in electronic applications, but they are produced as very heterogeneous mixtures with different properties so the achievement of a significant commercial application has been elusive. The dimensions of single-wall carbon nanotubes are generally a nanometer wide, up to hundreds of microns long and the carbon nanotubes have anisotropic structures. They are processed to have shorter lengths but they need to be sorted by diameter and chirality...
December 24, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28048314/su-d-204-07-retrospective-correlation-of-dose-accuracy-with-regions-of-local-failure-for-early-stage-lung-cancer-patients-treated-with-stereotactic-body-radiotherapy
#13
S Devpura, H Li, C Liu, C Fraser, M Ajlouni, B Movsas, I Chetty
PURPOSE: To correlate dose distributions computed using six algorithms for recurrent early stage non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiotherapy (SBRT), with outcome (local failure). METHODS: Of 270 NSCLC patients treated with 12Gyx4, 20 were found to have local recurrence prior to the 2-year time point. These patients were originally planned with 1-D pencil beam (1-D PB) algorithm. 4D imaging was performed to manage tumor motion...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048272/mo-de-207b-10-impact-of-morphologic-characteristics-on-radiomics-features-from-contast-enhanced-ct-for-primary-lung-tumors
#14
D Fried, L Zhang, X Fave, G Ibbott, S Zhou, O Mawlawi, Z Liao, L Court
PURPOSE: Determine the impact of morphologic characteristics (e.g. necrosis, vascular enhancement, and cavitation) on radiomic features from contrast enhanced CT (CE-CT) in primary lung tumors. METHODS: We developed an auto-segmentation algorithm to separate lung tumors on contrast-enhanced CT into cavitation (air), necrosis, tissue, and enhancing vessels using a combination of thresholding and region-growing. An auto-segmentation algorithm was also designed to identify necrosis on FDG-PET scans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048226/su-f-r-35-repeatability-of-texture-features-in-t1-and-t2-weighted-mr-images
#15
R Mahon, E Weiss, J Ford, K Karki, G Hugo
PURPOSE: To evaluate repeatability of lung tumor texture features from inspiration/expiration MR image pairs for potential use in patient specific care models and applications. Repeatability is a desirable and necessary characteristic of features included in such models. METHODS: T1-weighted Volumetric Interpolation Breath-Hold Examination (VIBE) and/or T2-weighted MRI scans were acquired for 15 patients with non-small cell lung cancer before and during radiotherapy for a total of 32 and 34 same session inspiration-expiration breath-hold image pairs respectively...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047196/th-ab-207a-11-anatomical-and-functional-assessment-of-coronary-artery-disease-using-low-dose-whole-organ-dynamic-computed-tomography
#16
L Hubbard, B Ziemer, J Lipinski, S Malkasian, B Sadeghi, H Javan, B Dertli, E M Groves, S Molloi
PURPOSE: To evaluate the accuracy of a low-dose, first-pass-analysis (FPA) dynamic computed tomography angiography and perfusion (CTAP) technique, for whole-organ anatomical and functional assessment of coronary artery disease (CAD). METHODS: An angioplasty balloon was advanced into the left anterior descending (LAD) coronary artery of five swine (35-45 kg) to induce several levels of stenosis at maximal hyperemia (intracoronary adenosine, 240 µg/min). Reference fluorescence microspheres and intravenous contrast (370 mg/mL iodine, 25 mL, 7 mL/s) were injected centrally and dynamic imaging was performed using a 320-slice CT scanner at 100 kVp and 200 mA...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047158/su-d-207b-01-radiomics-feature-reproducibility-from-repeat-ct-scans-of-patients-with-rectal-cancer
#17
P Hu, J Wang, H Zhong, Z Zhou, L Shen, W Hu, Z Zhang
PURPOSE: To evaluate the reproducibility of radiomics features by repeating computed tomographic (CT) scans in rectal cancer. To choose stable radiomics features for rectal cancer. METHODS: 40 rectal cancer patients were enrolled in this study, each of whom underwent two CT scans within average 8.7 days (5 days to 17 days), before any treatment was delivered. The rectal gross tumor volume (GTV) was distinguished and segmented by an experienced oncologist in both CTs...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043699/effect-of-phosphate-buffer-on-aggregation-kinetics-of-citrate-coated-silver-nanoparticles-induced-by-monovalent-and-divalent-electrolytes
#18
K Afshinnia, M Baalousha
The attachment efficiency (α) is an important parameter that can be used to characterize nanoparticle (NPs) aggregation behavior and has been a topic of discussion of several papers in the past few years. The importance of α is because it is one of the key parameters that can be used to model NP environmental fate and behavior. This study uses UV-vis and laser Doppler electrophoresis to monitor the aggregation behavior of citrate-coated silver nanoparticles (cit-AgNPs) induced by Na(+) and Ca(2+) as counter ions in the presence and absence of Suwannee River fulvic acid (SRFA) as a surrogate of natural organic matter and different concentrations of phosphate buffer (0-1mM)...
December 30, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28027839/countercurrent-chromatography-separation-of-saponins-by-skeleton-type-from-ampelozizyphus-amazonicus-for-off-line-ultra-high-performance-liquid-chromatography-high-resolution-accurate-mass-spectrometry-analysis-and-characterisation
#19
Fabiana de Souza Figueiredo, Rita Celano, Danila de Sousa Silva, Fernanda das Neves Costa, Peter Hewitson, Svetlana Ignatova, Anna Lisa Piccinelli, Luca Rastrelli, Suzana Guimarães Leitão, Gilda Guimarães Leitão
Ampelozizyphus amazonicus Ducke (Rhamnaceae), a medicinal plant used to prevent malaria, is a climbing shrub, native to the Amazonian region, with jujubogenin glycoside saponins as main compounds. The crude extract of this plant is too complex for any kind of structural identification, and HPLC separation was not sufficient to resolve this issue. Therefore, the aim of this work was to obtain saponin enriched fractions from the bark ethanol extract by countercurrent chromatography (CCC) for further isolation and identification/characterisation of the major saponins by HPLC and MS...
December 19, 2016: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28018914/clinical-acceptability-of-the-internal-gap-of-cad-cam-pd-ag-crowns-using-intraoral-digital-impressions
#20
Tae-Gyung Kim, Sungtae Kim, Hyunmin Choi, Jae-Hoon Lee, Jae-Hong Kim, Hong-Seok Moon
The purpose of this study was to compare the internal gap between CAD/CAM palladium-silver crowns and cast gold crowns generated from intraoral digital versus conventional impressions and to determine the clinical acceptability. Nickel-chrome master dies were made from the prepared resin tooth with the conventional impression method (n = 40). For ICC (Intraoral, CAD/CAM) group, 10 intraoral digital impressions were made, and 10 CAD/CAM crowns of a PD-AG (palladium-silver) machinable alloy were generated. For IC (Intraoral, Cast) group, 10 gold crowns were cast from ten intraoral digital impressions...
2016: BioMed Research International
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