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https://www.readbyqxmd.com/read/28731820/uncommon-neoplasms-of-the-biliary-tract-radiological-findings
#1
Vincenza Granata, Roberta Fusco, Orlando Catalano, Salvatore Filice, Antonio Avallone, Mauro Piccirillo, Maddalena Leongito, Raffaele Palaia, Roberto Grassi, Francesco Izzo, Antonella Petrillo
OBJECTIVES: To report our cancer center experience in the biliary tumors incidence other than cholangiocellular-carcinoma (CCC), emphasizing the radiological features. METHODS: 197 patients with biliary disease undergoing Gd-EOB-DTPA-enhanced MRI were reviewed. Four radiologists evaluated retrospectively size, structure, anatomical site, and signal intensity of lesions on MRI. Enhancement-pattern during the arterial-, portal-, and late-phase on US, CT and MR study was assessed as well as the enhancement pattern during the hepatobiliary-phase on MRI...
July 21, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28728718/cardiothoracic-critical-care
#2
REVIEW
Kevin W Lobdell, Douglas W Haden, Kshitij P Mistry
High-value CCC is rapidly evolving to meet the demands of increased patient acuity and to incorporate advances in technology. The high-performing CCC system and culture should aim to learn quickly and continuously improve. CCC demands a proactive, interactive, precise, an expert team, and continuity.
August 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28725409/development-of-methane-conversion-factor-models-for-zebu-beef-cattle-fed-low-quality-crop-residues-and-by-products-in-tropical-regions
#3
Chatchai Kaewpila, Kritapon Sommart
The enteric methane conversion factor (Ym) is an important country-specific value for the provision of precise enteric methane emissions inventory reports. The objectives of this meta-analysis were to develop and evaluate the empirical Ym models for the national level and the farm level for tropical developing countries according to the IPCC's categorization. We used datasets derived from 18 in vivo feeding experiments from 1999 to 2015 of Zebu beef cattle breeds fed low-quality crop residues and by-products...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28723905/evolution-of-anti-trypanosoma-cruzi-antibody-production-in-patients-with-chronic-chagas-disease-correlation-between-antibody-titers-and-development-of-cardiac-disease-severity
#4
Ingebourg Georg, Alejandro Marcel Hasslocher-Moreno, Sergio Salles Xavier, Marcelo Teixeira de Holanda, Eric Henrique Roma, Maria da Gloria Bonecini-Almeida
Chagas disease is one of the most important endemic infections in Latin America affecting around 6-7 million people. About 30-50% of patients develop the cardiac form of the disease, which can lead to severe cardiac dysfunction and death. In this scenario, the identification of immunological markers of disease progression would be a valuable tool for early treatment and reduction of death rates. In this observational study, the production of anti-Trypanosoma cruzi antibodies through a retrospective longitudinal follow-up in chronic Chagas disease patients´ cohort and its correlation with disease progression and heart commitment was evaluated...
July 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28717041/activation-of-sting-in-hepatocytes-suppresses-the-replication-of-hepatitis-b-virus
#5
Fang Guo, Liudi Tang, Sainan Shu, Mohit Sehgal, Muhammad Sheraz, Bowei Liu, Qiong Zhao, Junjun Cheng, Xuesen Zhao, Tianlun Zhou, Jinhong Chang, Ju-Tao Guo
Induction of interferon and proinflammatory cytokines is a hallmark of the infection of many different viruses. However, hepatitis B virus (HBV) does not elicit a detectable cytokine response in infected hepatocytes. In order to investigate the molecular mechanism underlying the innate immune evasion, a functional cGAS-STING pathway was reconstituted in a human hepatoma cell line supporting tetracycline-inducible HBV replication. It was demonstrated that induction of HBV replication neither activated nor inhibited this cytosolic DNA sensing pathway...
July 17, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28708732/investigating-the-robustness-neighborhood-gray-tone-difference-matrix-and-gray-level-co-occurrence-matrix-radiomic-features-on-clinical-computed-tomography-systems-using-anthropomorphic-phantoms-evidence-from-a-multivendor-study
#6
Usman Mahmood, Aditya P Apte, Joseph O Deasy, C Ross Schmidtlein, Amita Shukla-Dave
OBJECTIVE: The aim of this study was to determine if optimized imaging protocols across multiple computed tomography (CT) vendors could result in reproducible radiomic features calculated from an anthropomorphic phantom. METHODS: Materials with varying degrees of heterogeneity were placed throughout the lungs of the phantom. Twenty scans of the phantom were acquired on 3 CT manufacturers with chest CT protocols that had optimized protocol parameters. Scans were reconstructed using vendor-specific standards and lung kernels...
July 13, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28706597/an-infrequent-cause-of-apical-ventricular-aneurysm-in-the-united-states
#7
Mohammed M Taleb
Chronic Chagas cardiomyopathy (CCC) is a late complication of Chagas disease with various manifestations including arrhythmia, heart failure, thromboembolism, and stroke. In a patient with symptoms of heart failure and left ventricular apical aneurysm unexplained by structural heart or coronary vascular abnormalities, CCC should be strongly considered and inquiry made about exposure status. Typical electrocardiographic findings of bundle branch block, complete heart blocks, and ventricular arrhythmia are helpful clues...
April 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/28704130/scleral-thinning-documented-by-ultrasound-biomicroscopy-after-plaque-therapy-for-anterior-ciliary-melanoma
#8
B Kuzmanović Elabjer, M Bušić, D Miletić, M Bjeloš, N Vukojević, D Bosnar
PURPOSE: To evaluate, by ultrasound biomicroscopy (UBM), changes in scleral thickness after ruthenium-106 CCB and CCC plaque (Eckert & Ziegler BE-BIG GmbH, Berlin, Germany) therapy for anterior ciliary melanoma. METHODS: Eleven patients with anterior ciliary melanoma underwent ruthenium-106 CCB and CCC plaque radiation with a radiation dose at the tumor apex of 80-100 Gy. UBM measurements performed prior to and after treatment were as follows: the largest prominence of the tumor perpendicular to the sclera and scleral thickness at scleral spur, 1...
July 13, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28700046/association-between-tgf%C3%AE-1-polymorphisms-and-chronic-hepatitis-b-infection-in-an-iranian-population
#9
Ebrahim Eskandari, Malihe Metanat, Elham Pahlevani, Tooba Nakhzari-Khodakheir
INTRODUCTION: Transforming growth factor-beta 1 (TGFβ1) is a potent suppressive cytokine that contributes to chronic hepatitis B (CHB) infection. Disparities in TGFβ1 production among individuals have been attributed to TGFβ1 genetic polymorphisms. We examined whether three putative polymorphisms in TGFβ1[-509 C/T (rs1800469), +869 C/T (rs1800470), and +11929 C/T (rs1800472)]are associated with CHB infection in a South-Eastern Iranian population. METHODS: In total, 341 subjects were recruited, including 178 patients with CHB and 163 healthy individuals as controls...
May 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28700032/lipoprotein-a-as-a-predictor-of-poor-collateral-circulation-in-patients-with-chronic-stable-coronary-heart-disease
#10
Y Fan, J-S Hu, F Guo, Z-B Lu, H Xia
As a mechanism compensating for obstructive coronary artery disease, coronary collateral circulation (CCC) has attracted cardiologists for a long time to explore its potential impact. In the present study, Chinese patients suffering from ≥95% coronary stenosis, as diagnosed by angiography, have been investigated for the correlation between CCC and lipoprotein(a) [Lp(a)] levels. A cohort of 654 patients was divided into four categories according to Rentrop grades 0, 1, 2, and 3. Lp(a) levels were divided into model 1, discretized with critical values of 33 and 66%, and model 2, discretized with a cutoff value of 30...
July 10, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28698315/translation-adaptation-and-measurement-properties-of-an-electronic-version-of-the-danish-western-ontario-shoulder-instability-index-wosi
#11
Henrik Eshoj, Klaus Bak, Lars Blønd, Birgit Juul-Kristensen
OBJECTIVES: To translate and adapt the Western Ontario Shoulder Instability (WOSI) questionnaire into Danish and, to evaluate measurement properties of an electronic Danish WOSI version. METHODS: The Swedish WOSI version was used for translation and adaptation into Danish followed by examination of test-retest reproducibility (14-day interval) besides concurrent and construct validity. Concurrent validity was examined by comparing WOSI in paper version with an electronic version, whereas construct validity was examined by comparing WOSI with Numeric Pain Rating Scale (NPRS) and the Oxford Shoulder Score (OSS)...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28695437/quantitative-aspects-of-communicative-impairment-ascertained-in-a-large-national-survey-of-japanese-children
#12
Manabu Oi, Hiroshi Fujino, Naotake Tsukidate, Yoko Kamio, Yuko Yoshimura, Mitsuru Kikuchi, Chiaki Hasegawa, Keiko Gondou, Tomoko Matsui
The Japanese version of the Children's Communication Checklist-2 (CCC-2) was rated by caregivers in a large national population sample of 22,871 children aged 3-15 years. The General Communication Composite (GCC) of the CCC-2 exhibited a distribution with a single-factor structure. The GCC distribution between autism spectrum disorders (ASD) and language impairment (LI) groups in the general population fit inside a bell curve with significant overlap with the general population, and a continuum was evident between groups...
July 10, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28686017/analysis-and-characterization-of-polychlorinated-hydroxybornanes-as-metabolites-of-toxaphene-using-polar-bear-model
#13
Lea Reger, Christoph Gallistl, Karl Skirnisson, Walter Vetter
Abiotic and biotic transformation of toxaphene (camphechlor) results in the selective enrichment of recalcitrant congeners while other, less persistent compounds of technical toxaphene (CTTs) are degraded. Up to now there is little knowledge on oxidation transformation of toxaphene. For instance, existence of hydroxylated CTTs (OH-CTTs) in authentic environmental and food samples was not proven yet. For this reason, we synthesized a mixture consisting of tetra- to heptachlorinated OH-CTTs and simplified it by countercurrent chromatography (CCC)...
July 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28685580/association-of-igf-1-with-coronary-collateral-circulation-in-stable-coronary-artery-disease
#14
Harun Kundi, Murat Gok, Emrullah Kiziltunc, Mustafa Cetin, Ender Ornek
AIM: The aim of the present study is to evaluate the relationship between coronary collateral circulation (CCC) grade and serum IGF-1 levels in patients diagnosed with stable coronary artery disease. METHODS: Totally, 190 consecutive patients with stable coronary artery disease who underwent coronary angiography were included in this study. RESULTS: The patients with good CCC had significantly higher IGF-1 levels compared with the poor ones...
July 7, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28682926/evaluation-of-the-novel-methotrexate-architect-chemiluminescent-inmunoassay-clinical-impact-on-pharmacokinetic-monitoring
#15
María Dolores Aumente, Julia López-Santamaría, Concepción Donoso-Rengifo, Inmaculada Reyes-Torres, Pablo Montejano Hervás
BACKGROUND: Fluorescence polarization immunoassay (FPIA) has been probably the most widely used technique for the determination of methotrexate (MTX) concentrations in clinical laboratories. After its replacement by a novel Architect chemiluminescent microparticle immunoassay (CMIA), it is essential to verify that there are no differences between the methods that can induce an error in leucovorin rescue with dire consequences for the patient. The objective of our study was to compare plasma/serum MTX measurements between CMIA and FPIA, reference method in this study, in the work conditions of a clinical pharmacokinetics unit to determine whether any difference would affect clinical decisions on the management of this drug...
July 3, 2017: Therapeutic Drug Monitoring
https://www.readbyqxmd.com/read/28678144/relationship-of-mean-platelet-volume-to-lymphocyte-ratio-and-coronary-collateral-circulation-in-patients-with-stable-angina-pectoris
#16
Ender Ornek, Alparslan Kurtul
BACKGROUND: In patients with coronary artery disease, coronary collateral circulation (CCC) develops as an adaptation to ischemia and contributes toward reduction of cardiovascular events. Recently, the mean platelet volume-to-lymphocyte ratio (MPVLR) has emerged as a novel and readily available marker of inflammation and thrombosis. This study aimed to investigate the relationship between MPVLR and development of CCC. PATIENTS AND METHODS: A total of 332 patients with stable angina pectoris undergoing coronary arteriography were enrolled and divided on the basis of the development of CCC into two groups: group with adequate CCC (n=243) and group with impaired CCC (n=89)...
July 3, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28676300/can-residents-be-trained-and-safety-maintained
#17
Marina Gorelik, Steven Godelman, Adel Elkbuli, Lauren Allen, Dessy Boneva, Mark McKenney
INTRODUCTION: Teaching hospitals and faculty need to balance the educational mission for training residents with patient safety. There are no data studying the change in trauma patient outcomes before and after implementation of a surgical residency. The objective of this study was to compare trauma center outcomes before and after the advent of a surgical training program. We predicted that patient-centric outcome metrics would not be affected by the integration of surgical residents into trauma patient care...
July 1, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28672253/accuracy-of-a-cow-side-test-for-the-diagnosis-of-hyperketonemia-and-hypoglycemia-in-lactating-dairy-cows
#18
K Macmillan, I López Helguera, A Behrouzi, M Gobikrushanth, B Hoff, M G Colazo
The objective of this study was to evaluate the use of a cow-side device (FreeStyle Precision Neo™) to diagnose ketosis and hypoglycemia based on measures of blood β-hydroxybutyrate (BHBA) and glucose. Eleven commercial dairy farms were visited and blood samples were taken from Holstein cows between 2 and 14days in milk, yielding 441 samples for BHBA analysis and 308 samples for glucose analysis. Concentrations of BHBA and glucose were measured in two ways, 1) using the cow-side device with whole blood immediately after sampling and 2) serum samples analyzed with a standard laboratory assay (Animal Health Laboratory, University of Guelph, Canada)...
June 27, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28672016/quantitative-assessment-of-simultaneous-f-18-fdg-pet-mri-in-patients-with-various-types-of-hepatic-tumors-correlation-between-glucose-metabolism-and-apparent-diffusion-coefficient
#19
Eunjung Kong, Kyung Ah Chun, Ihn Ho Cho
PURPOSE: Metabolism and water diffusion may have a relationship or an effect on each other in the same tumor. Knowledge of their relationship could expand the understanding of tumor biology and serve the field of oncologic imaging. This study aimed to evaluate the relationship between metabolism and water diffusivity in hepatic tumors using a simultaneous positron emission tomography/magnetic resonance imaging (PET/MRI) system with F-18 fluorodeoxyglucose (FDG) and to reveal the metabolic and diffusional characteristics of each type of hepatic tumor...
2017: PloS One
https://www.readbyqxmd.com/read/28667768/chronic-toxicity-of-aluminum-at-a-ph-of-6-to-freshwater-organisms-empirical-data-for-the-development-of-international-regulatory-standards-criteria
#20
Allison S Cardwell, William J Adams, Robert W Gensemer, Eirik Nordheim, Robert C Santore, Adam C Ryan, William A Stubblefield
The chemistry, bioavailability, and toxicity of aluminum (Al) in the aquatic environment is complex and affected by a wide-range of water quality characteristics (pH, hardness, dissolved organic carbon). Data gaps in Al ecotoxicology exist for pH ranges representative of natural surface waters (pH 6-8). To address these gaps, a series of chronic toxicity tests were performed at pH 6 with eight freshwater species, including two fish (Pimephales promelas and Danio rerio); an oligochaete (Aeolosoma sp.); a rotifer (Brachionus calyciflorus); a snail (Lymnaea stagnalis); an amphipod (Hyalella azteca); a midge (Chironomus riparius); and an aquatic plant (Lemna minor)...
July 1, 2017: Environmental Toxicology and Chemistry
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