keyword
MENU ▼
Read by QxMD icon Read
search

CCC

keyword
https://www.readbyqxmd.com/read/28426745/objective-classification-of-zonular-weakness-based-on-lens-movement-at-the-start-of-capsulorhexis
#1
Saori Yaguchi, Shigeo Yaguchi, Yukari Yagi-Yaguchi, Tadahiko Kozawa, Hiroko Bissen-Miyajima
PURPOSE: To quantify zonular weakness based on lens movement at the start of continuous curvilinear capsulorhexis (CCC) and establish a classification system for it. SETTING: Kozawa Eye Hospital and Diabetes Center, Mito, Japan. DESIGN: Retrospective interventional case series. METHODS: We examined 402 consecutive eyes of 316 patients who underwent CCC, phacoemulsification and aspiration (PEA), and intraocular lens (IOL) implantation...
2017: PloS One
https://www.readbyqxmd.com/read/28419608/multiple-breath-hold-proton-spectroscopy-of-human-liver-at-3t-relaxation-times-and-concentrations-of-glycogen-choline-and-lipids
#2
Jan Weis, Joel Kullberg, Håkan Ahlström
PURPOSE: To evaluate the feasibility of an expiration multiple breath-hold (1) H-MRS technique to measure glycogen (Glycg), choline-containing compounds (CCC), and lipid relaxation times T1 , T2 , and their concentrations in normal human liver. MATERIALS AND METHODS: Thirty healthy volunteers were recruited. Experiments were performed at 3T. Multiple expiration breath-hold single-voxel point-resolved spectroscopy (PRESS) technique was used for localization. Water-suppressed spectra were used for the estimation of Glycg, CCC, lipid methylene (CH2 )n relaxation times and concentrations...
April 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28416754/unique-synergistic-formulation-of-curcumin-epicatechin-gallate-and-resveratrol-tricurin-suppresses-hpv-e6-eliminates-hpv-cancer-cells-and-inhibits-tumor-progression
#3
Sumit Mukherjee, Priya Ranjan Debata, Rahman Hussaini, Kaushiki Chatterjee, Juliet N E Baidoo, Samay Sampat, Anita Szerszen, Joseph P Navarra, Jimmie Fata, Elena Severinova, Probal Banerjee, Mario R Castellanos
Curcumin (from curry) (C) is highly potent against cervical cancer cells (CCC), but poor bioavailability has limited its clinical use. Similar natural polyphenols resveratrol (from grapes) (R), and epicatechin gallate (from green tea) (E) also display activity against CCC. By treating CCC (HeLa) with C, E, or R, or combinations of these compounds, we computed combination indices and observed a strong synergism among C, E, and R at the unique molar ratio 4:1:12.5. This combination, named as TriCurin, rapidly down regulated HPV18 E6 and NF-kB expression while concomitantly inducing the tumor suppressor protein p53 in HeLa cells...
March 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415970/drosophila-melanogaster-retrotransposon-and-inverted-repeat-derived-endogenous-sirnas-are-differentially-processed-in-distinct-cellular-locations
#4
Andrew W Harrington, Michael R McKain, Daniel Michalski, Kaylyn M Bauer, Joshua M Daugherty, Mindy Steiniger
BACKGROUND: Endogenous small interfering (esi)RNAs repress mRNA levels and retrotransposon mobility in Drosophila somatic cells by poorly understood mechanisms. 21 nucleotide esiRNAs are primarily generated from retrotransposons and two inverted repeat (hairpin) loci in Drosophila culture cells in a Dicer2 dependent manner. Additionally, proteins involved in 3' end processing, such as Symplekin, CPSF73 and CPSR100, have been recently implicated in the esiRNA pathway. RESULTS: Here we present evidence of overlap between two essential RNA metabolic pathways: esiRNA biogenesis and mRNA 3' end processing...
April 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28410716/clinical-performance-in-continuous-curvilinear-capsulorhexis-creation-supported-by-a-digital-image-guidance-system
#5
Yesim Haeussler-Sinangin, Dorothee Dahlhoff, Tim Schultz, H Burkhard Dick
PURPOSE: To test whether a default capsulorhexis diameter could be attained more precisely when manual continuous curvilinear capsulorhexis (CCC) creation was supported by a biomorphological detection unit. SETTING: Ruhr University Eye Hospital, Bochum, Germany. DESIGN: Prospective interventional study. METHODS: Patients were assigned to either of 2 groups. In the first group, a digital image system was applied to guide capsulorhexis...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28410708/twenty-nine-gauge-dual-chandelier-retroillumination-for-the-non-open-sky-continuous-curvilinear-capsulorhexis-in-the-penetrating-keratoplasty-triple-procedure
#6
Shunji Yokokura, Takehiro Hariya, Wataru Kobayashi, Yasuhiko Meguro, Kohji Nishida, Toru Nakazawa
We describe a technique for the penetrating keratoplasty (PKP) triple procedure that uses 29-gauge dual-chandelier illumination during creation of a non-open-sky continuous curvilinear capsulorhexis (CCC). The chandeliers are inserted through the pars plana into the vitreous cavity through the bulbar conjunctiva at the 3 o'clock and 9 o'clock positions. We compared this approach with that of a core vitrectomy, in which a single 25-gauge port is inserted into the vitreous cavity transconjunctivally through the upper temporal pars plana...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28409843/reproducibility-of-quantitative-high-throughput-bi-rads-features-extracted-from-ultrasound-images-of-breast-cancer
#7
Yuzhou Hu, Mengyun Qiao, Yi Guo, Yuanyuan Wang, Jinhua Yu, Jiawei Li, Cai Chang
PURPOSE: Digital Breast Imaging Reporting and Data System (BI-RADS) features extracted from ultrasound images are essential in computer-aided diagnosis, prediction, and prognosis of breast cancer. This study focuses on the reproducibility of quantitative high-throughput BI-RADS features in the presence of variations due to different segmentation results, various ultrasound machine models, and multiple ultrasound machine settings. METHODS: Data set 1 consists of 399 patients with invasive breast cancer and is used as the training set to measure the reproducibility of features, while data set 2 consists of 138 other patients and is a validation set used to evaluate the diagnosis performances of the final reproducible features...
April 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28407220/patient-controlled-analgesia-with-remifentanil-versus-alternative-parenteral-methods-for-pain-management-in-labour
#8
REVIEW
Stephanie Weibel, Yvonne Jelting, Arash Afshari, Nathan Leon Pace, Leopold Hj Eberhart, Johanna Jokinen, Thorsten Artmann, Peter Kranke
BACKGROUND: Multiple analgesic strategies for pain relief during labour are available. Recently remifentanil, a short-acting opioid, has recently been used as an alternative analgesic due to its unique pharmacological properties. OBJECTIVES: To systematically assess the effectiveness of remifentanil intravenous patient-controlled analgesia (PCA) for labour pain, along with any potential harms to the mother and the newborn. SEARCH METHODS: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (9 December 2015), ClinicalTrials...
April 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28401450/reproducibility-and-prognostic-potential-of-ki-67-proliferation-index-when-comparing-digital-image-analysis-with-standard-semi-quantitative-evaluation-in-breast-cancer
#9
Balázs Ács, Lilla Madaras, Kristóf Attila Kovács, Tamás Micsik, Anna-Mária Tőkés, Balázs Győrffy, Janina Kulka, Attila Marcell Szász
In this study, the reproducibility of Ki-67 proliferation index (KIPI) was investigated by comparing the semi-quantitative (SQ) results of three assessors with those of digital image-analysis (DIA) methods. The prognostic significance of the two approaches was also correlated with clinical outcome. Tissue microarrays of duplicate 2 mm cores were constructed from representative areas of formalin-fixed and paraffin-embedded tumor blocks of 347 breast cancer patients. SQ evaluation of Ki-67 (MIB1 clone) immunostained slides was performed independently by three pathologists...
April 11, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28396681/evolution-of-nucleotide-punctuation-marks-from-structural-to-linear-signals
#10
Nawal El Houmami, Hervé Seligmann
We present an evolutionary hypothesis assuming that signals marking nucleotide synthesis (DNA replication and RNA transcription) evolved from multi- to unidimensional structures, and were carried over from transcription to translation. This evolutionary scenario presumes that signals combining secondary and primary nucleotide structures are evolutionary transitions. Mitochondrial replication initiation fits this scenario. Some observations reported in the literature corroborate that several signals for nucleotide synthesis function in translation, and vice versa...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28393589/endocan-levels-and-coronary-collateral-circulation-in-stable-angina-pectoris-a-pilot-study
#11
Murat Gok, Harun Kundi, Emrullah Kiziltunc, Canan Topcuoglu, Ender Ornek
We investigated the relationship between endocan (a marker of systemic inflammation) and the development of coronary collateral circulation (CCC) as evaluated by coronary angiography in patients with chronic stable angina pectoris. A total of 90 patients (32 poor CCC and 58 good CCC) were included in this study. Endocan levels were determined using a commercially available sandwich enzyme-linked immunosorbent assay kit with high sensitivity and specificity for detection of human endocan. In multivariate logistic regression analysis, low endocan levels were independently associated with good CCC ( P < ...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28392369/compression-to-ventilation-ratio-and-incidence-of-rearrest-a-secondary-analysis-of-the-roc-ccc-trial
#12
David D Salcido, Robert H Schmicker, Jason E Buick, Sheldon Cheskes, Brian Grunau, Peter Kudenchuk, Brian Leroux, Stephanie Zellner, Dana Zive, Tom P Aufderheide, Allison C Koller, Heather Herren, Jack Nuttall, Matthew L Sundermann, James J Menegazzi
BACKGROUND: Previous work has demonstrated that when out-of-hospital cardiac arrest (OHCA) patients achieve return of spontaneous circulation (ROSC), but subsequently have another cardiac arrest prior to hospital arrival (rearrest), the probability of survival to hospital discharge is significantly decreased. Additionally, few modifiable factors for rearrest are known. We sought to examine the association between rearrest and compression-to-ventilation ratio during cardiopulmonary resuscitation (CPR) and to confirm the association between rearrest and outcomes...
April 6, 2017: Resuscitation
https://www.readbyqxmd.com/read/28392048/properties-of-hydrodynamic-j-type-countercurrent-chromatography-for-protein-separation-using-aqueous-two-phase-systems-with-special-reference-to-constructing-conical-columns
#13
Jianjian Ding, Shifei Li, Yuqing Zhao, Yue Hugh Guan, Li Deng, Qiuyun Deng
Protein separation using hydrodynamic countercurrent chromatography (CCC), where low backpressure is inherent, is more challenging, more time consuming and more costly when compared with separating small molecules. The most hopeful approach is to rationally design suitable columns for already commercialized J-type CCC machinery. By comparing 3 column geometries (3D helix, 2D spiral and 3D cone), we firstly constructed the mechanical model tailored to the conical column on J-type CCC using aqueous two-phase system (ATPS) on protein separation...
March 31, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28389144/clear-cell-carcinomas-of-the-ovary-have-poorer-outcomes-compared-with-serous-carcinomas-results-from-a-single-center-taiwanese-study
#14
Fei-Chun Ku, Ren-Chin Wu, Lan-Yan Yang, Yun-Hsin Tang, Wei-Yang Chang, Jung-Erh Yang, Chun-Chieh Wang, Shih-Ming Jung, Cheng-Tao Lin, Ting-Chang Chang, Angel Chao, Chyong-Huey Lai
BACKGROUND/PURPOSE: To compare the clinical outcomes of Taiwanese patients with ovarian clear cell carcinomas (CCCs) and serous carcinomas (SCs). METHODS: We retrieved the clinical records of women with epithelial ovarian cancer (Stage I-IV) who received primary surgeries between 2000 and 2013. Cancer-specific survival (CSS), progression-free survival, and survival after recurrence (SAR) of CCC and SC patients were retrospectively compared. Multivariate analysis was used to identify the independent predictors of survival...
April 4, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28383472/battlefield-pain-management-a-view-of-17-years-in-israel-defense-forces
#15
Avi Benov, Margaux M Salas, Helit Nakar, Ben Antebi, Bader Tarif, Avraham Yitzhak, Elon Glassberg
INTRODUCTION: Pain control in trauma is an integral part of treatment in combat casualty care (CCC). More soldiers injured on the battlefield will need analgesics for pain than those who will need life-saving interventions (LSI). It has been shown that early treatment of pain improves outcomes after traumatic injury, while inadequate treatment leads to higher rates of PTSD. The purpose of this article is to report the Israel Defense Forces Medical Corps (IDF-MC) experience with point of injury (POI) use of analgesia...
April 5, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28382796/inhibition-of-autophagy-protein-lc3a-as-a-therapeutic-target-in-ovarian-clear-cell-carcinomas
#16
Morikazu Miyamoto, Masashi Takano, Tadashi Aoyama, Hiroaki Soyama, Tomoyuki Yoshikawa, Hitoshi Tsuda, Kenichi Furuya
OBJECTIVE: Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been determined. METHODS: The present study investigated whether expression of autophagy-related protein, light chain 3A (LC3A), was related with prognoses in the patients with CCC using immuno-histochemical stainings, and whether inhibition of autophagy modified the sensitivity to cisplatin in CCC cells in vitro...
May 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28380707/implementing-sustainable-evidence-based-interventions-in-the-community
#17
Carey Wexler Sherman, Sally C Steiner
Evidence-based (EB) programs provide a tested means for addressing serious public health concerns. While establishing and maintaining fidelity to these programs is critical for high-quality outcomes, unfortunately, implementation reports rarely describe the strategies used to train and monitor fidelity in community-based implementations. Thus, an essential translational ingredient is a clearly articulated model for establishing a systemic, sustainable fidelity framework. This article provides a detailed description of the fidelity-focused framework developed for Michigan's statewide implementation of the Savvy Caregiver Program...
December 1, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28374329/the-prevalence-of-tandem-spinal-stenosis-and-its-characteristics-in-a-population-based-mri-study-the-wakayama-spine-study
#18
Keiji Nagata, Noriko Yoshimura, Hiroshi Hashizume, Yuyu Ishimoto, Shigeyuki Muraki, Hiroshi Yamada, Hiroyuki Oka, Hiroshi Kawaguchi, Toru Akune, Sakae Tanaka, Kozo Nakamura, Munehito Yoshida
PURPOSE: Tandem spinal stenosis (TSS) is a condition of combined spinal stenosis in the cervical and lumbar regions. The purpose of this study was to determine the prevalence of radiographic TSS and its association with developmental canal stenosis (DCS). The second purpose was to investigate the extent to which radiographic TSS is associated with cervical myelopathy and symptomatic LSS. METHODS: We recruited 1011 (336 men and 675 women) participants in this population-based study...
April 3, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28370487/contrast-induced-nephropathy-in-patients-undergoing-endovascular-peripheral-vascular-intervention-incidence-risk-factors-and-outcomes-as-observed-in-the-blue-cross-blue-shield-of-michigan-cardiovascular-consortium
#19
P Michael Grossman, Syed S Ali, Herbert D Aronow, Michael Boros, Timothy J Nypaver, Theodore L Schreiber, Yeo Jung Park, Peter K Henke, Hitinder S Gurm
BACKGROUND: The incidence, risk factors, and outcomes associated with Contrast-induced nephropathy (CIN) after Percutaneous Vascular Intervention (PVI) in contemporary medical practice are largely unknown. METHODS: A total of 13 126 patients undergoing PVI were included in the analysis. CIN was defined as an increase in serum creatinine from pre-PVI baseline to post-PVI peak Cr of ≥0.5 mg/dL. RESULTS: CIN occurred in 3% (400 patients) of the cohort, and 26 patients (6...
April 3, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28370303/technical-note-monte-carlo-study-of-106-ru-106-rh-ophthalmic-plaques-including-the-106-rh-gamma-spectrum
#20
Marcelino Hermida-López, Lorenzo Brualla
PURPOSE: To assess the influence of the (106) Rh gamma spectrum on the Monte Carlo simulation of (106) Ru/(106) Rh ophthalmic plaques, which has been neglected without a quantitative estimation in all previous publications. METHODS: Simulations were run with the penelope 2014 Monte Carlo code for radiation transport. Depth-dose distributions in water were simulated for the plaque models CCA, CCC, CCX and CIA. In addition to the (106) Rh beta spectrum, all gamma components from the (106) Rh gamma spectrum were included in the simulations...
April 1, 2017: Medical Physics
keyword
keyword
56522
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"