S-Y Li, X-Y Xie, D Liu, G-R Cheng, F-F Hu, D-Y Zeng, X-C Chen, L-F Jia, Y-J Wang, X-L Bu, C Qiu, F Gao, J-G Gu, M-F Liu, Y Li, Y-L Zhou, H-J Chang, Y-M Ou, L Xu, Z-X Wu, J-J Zhang, J-Y Wang, L-Y Huang, Y-Y Cui, J Zhou, X-C Liu, J Liu, Q-Q Nie, D Song, C Cai, G-B Han, X Yang, W Tan, J-T Yu, Y Zeng
BACKGROUND: Alzheimer's disease (AD), the most common type of irreversible dementia, is predicted to affect 152 million people by 2050. Evidence from large-scale preventive randomized controlled trials (RCTs) on modifiable risk variables in Europe has shown that multi-domain lifestyle treatments for older persons at high risk of dementia may be practical and effective. Given the substantial differences between the Chinese and European populations in terms of demographics and living conditions, direct adoption of the European program in China remains unfeasible...
2024: Journal of Prevention of Alzheimer's Disease