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https://www.readbyqxmd.com/read/29144718/the-emerging-role-of-gammacore%C3%A2-in-the-management-of-cluster-headache-expert-panel-recommendations
#1
Stephen D Silberstein, Anne H Calhoun, Christina Treppendahl, David W Dodick, Alan M Rapoport, Avinash Mamidi, Peter Vargas, Thomas H Ebert, Stewart J Tepper
A panel of 9 experts, including neurologists, other headache specialists, and medical and pharmacy directors, from 4 health plans (1 integrated delivery network and 3 plans with commercial, Medicare, and Medicaid lines of business), convened to discuss cluster headache (CH). Topics covered included the current treatment landscape, treatment challenges, economic impact of disease, and gaps in care for patients with CH. One major challenge in the management of CH is that it is underrecognized and frequently misdiagnosed, leading to delays in and suboptimal treatment for patients who suffer from this painful and disabling condition...
November 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29139572/exposing-ecological-and-economic-costs-of-the-research-implementation-gap-and-compromises-in-decision-making
#2
Santtu Kareksela, Atte Moilanen, Olli Ristaniemi, Reima Välivaara, Janne S Kotiaho
The frequently discussed gap between conservation science and practice is manifest in the gap between spatial conservation prioritization plans and their implementation. We analyzed the research-implementation gap of 1 zoning case by comparing results of a spatial prioritization analysis aimed at avoiding ecological impact of peat mining in a regional zoning process with the final zoning plan. We examined the relatively complex planning process to determine the gaps among research, zoning, and decision making...
November 15, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29136016/monitoring-the-effects-of-land-cover-change-on-the-supply-of-ecosystem-services-in-an-urban-region-a-study-of-santiago-valpara%C3%A3-so-chile
#3
Claudia Montoya-Tangarife, Francisco de la Barrera, Alejandro Salazar, Luis Inostroza
Mankind's quest for well-being results in continuous pressure to transform landscapes, with said transformation driven by land use changes, urbanization, production activity, and protective measures in addition to climate variability and other environmental drivers. The relationship between anthropogenic landscape changes and the provision of ecosystem services (ES) is a topic of increasing interest in Latin America. In Chile, land cover changes due to increased urbanization and forestry, and expansion of agricultural land, in addition to conservation initiatives as a part of land planning, have been intensive in the last few decades...
2017: PloS One
https://www.readbyqxmd.com/read/29132298/population-genetic-structure-is-shaped-by-historical-geographic-and-environmental-factors-in-the-leguminous-shrub-caragana-microphylla-on-the-inner-mongolia-plateau-of-china
#4
Bo Xu, Guoli Sun, Xuemin Wang, Jingwei Lu, Ian J Wang, Zan Wang
BACKGROUND: Understanding how landscape factors, including suites of geographic and environmental variables, and both historical and contemporary ecological and evolutionary processes shape the distribution of genetic diversity is a primary goal of landscape and conservation genetics and may be particularly consequential for species involved in ecological restoration. In this study, we examine the factors that shape the distribution of genetic variation in a leguminous shrub (Caragana microphylla) important for restoration efforts on the Mongolian Plateau in China...
November 13, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29124788/need-for-multiscale-planning-for-conservation-of-urban-bats
#5
Travis Gallo, Elizabeth W Lehrer, Mason Fidino, R Julia Kilgour, Patrick J Wolff, Seth Magle
For over a century there have been continual efforts to incorporate nature into urban planning. These efforts - known as urban reconciliation- aim to manage and create habitats that support biodiversity within cities. Given that species select habitat at different spatial scales, understanding the scale at which urban species respond to their environment is critical to the success of urban reconciliation efforts. We assessed species-habitat relationships for common bat species at local (50-m), medium (500-m), and broad (1-km) spatial scales in the Chicago metropolitan area and predicted bat activity across the greater Chicago region...
November 10, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29121600/use-of-surrogate-indicators-for-the-evaluation-of-potential-health-risks-due-to-poor-urban-water-quality-a-bayesian-network-approach
#6
Buddhi Wijesiri, Kaveh Deilami, James McGree, Ashantha Goonetilleke
Urban water pollution poses risks of waterborne infectious diseases. Therefore, in order to improve urban liveability, effective pollution mitigation strategies are required underpinned by predictions generated using water quality models. However, the lack of reliability in current modelling practices detrimentally impacts planning and management decision making. This research study adopted a novel approach in the form of Bayesian Networks to model urban water quality to better investigate the factors that influence risks to human health...
November 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29121066/probability-of-lek-collapse-is-lower-inside-sage-grouse-core-areas-effectiveness-of-conservation-policy-for-a-landscape-species
#7
Emma Suzuki Spence, Jeffrey L Beck, Andrew J Gregory
Greater sage-grouse (Centrocercus urophasianus) occupy sagebrush (Artemisia spp.) habitats in 11 western states and 2 Canadian provinces. In September 2015, the U.S. Fish and Wildlife Service announced the listing status for sage-grouse had changed from warranted but precluded to not warranted. The primary reason cited for this change of status was that the enactment of new regulatory mechanisms was sufficient to protect sage-grouse populations. One such plan is the 2008, Wyoming Sage Grouse Executive Order (SGEO), enacted by Governor Freudenthal...
2017: PloS One
https://www.readbyqxmd.com/read/29114438/assessment-of-fine-scale-resource-selection-and-spatially-explicit-habitat-suitability-modelling-for-a-re-introduced-tiger-panthera-tigris-population-in-central-india
#8
Mriganka Shekhar Sarkar, Ramesh Krishnamurthy, Jeyaraj A Johnson, Subharanjan Sen, Goutam Kumar Saha
Background: Large carnivores influence ecosystem functions at various scales. Thus, their local extinction is not only a species-specific conservation concern, but also reflects on the overall habitat quality and ecosystem value. Species-habitat relationships at fine scale reflect the individuals' ability to procure resources and negotiate intraspecific competition. Such fine scale habitat choices are more pronounced in large carnivores such as tiger (Panthera tigris), which exhibits competitive exclusion in habitat and mate selection strategies...
2017: PeerJ
https://www.readbyqxmd.com/read/29109425/landscape-scale-conservation-design-across-biotic-realms-sequential-integration-of-aquatic-and-terrestrial-landscapes
#9
Paul B Leonard, Robert F Baldwin, R Daniel Hanks
Systematic conservation planning has been used extensively throughout the world to identify important areas for maintaining biodiversity and functional ecosystems, and is well suited to address large-scale biodiversity conservation challenges of the twenty-first century. Systematic planning is necessary to bridge implementation, scale, and data gaps in a collaborative effort that recognizes competing land uses. Here, we developed a conservation planning process to identify and unify conservation priorities around the central and southern Appalachian Mountains as part of the Appalachian Landscape Conservation Cooperative (App LCC)...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29107801/linear-infrastructure-impacts-on-landscape-hydrology
#10
Keren G Raiter, Suzanne M Prober, Hugh P Possingham, Fiona Westcott, Richard J Hobbs
The extent of roads and other forms of linear infrastructure is burgeoning worldwide, but their impacts are inadequately understood and thus poorly mitigated. Previous studies have identified many potential impacts, including alterations to the hydrological functions and soil processes upon which ecosystems depend. However, these impacts have seldom been quantified at a regional level, particularly in arid and semi-arid systems where the gap in knowledge is the greatest, and impacts potentially the most severe...
November 3, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29076179/the-ecological-consequences-of-forest-elephant-declines-for-afrotropical-forests
#11
John R Poulsen, Cooper Rosin, Amelia Meier, Emily Mills, Chase Nunez, Sally E Koerner, Emily Blanchard, Jennifer Callejas, Sarah Moore, Mark Sowers
Poaching is rapidly extirpating African forest elephants (Loxodonta cyclotis) from most of their historical range, leaving vast areas of elephant-free tropical forest. Elephants are ecological engineers that create and maintain forest habitat, thus their loss will have strong consequences for the composition and structure of Afrotropical forests. We evaluated the roles of forest elephants in seed dispersal, nutrient recycling, and herbivory and physical damage to predict the cascading ecological effects of their population declines...
October 27, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29056623/the-raise-coalition-lessons-learned-from-a-multisector-coalition-used-to-implement-high-impact-population-wide-strategies-in-cleveland-ohio
#12
Pedro Arista, Cathy Vue, Michael Byun, Ashley Choi, Kathy Ko Chin
BACKGROUND: Recent public health initiatives include policy, systems, and environmental (PSE) strategies with the aim of improving community health. These high-impact, population-wide strategies provide opportunities for multisector coalitions to engage and inform the implementation process to ultimately reach underrepresented communities, like Asian Americans and Pacific Islanders (AAPIs). OBJECTIVES: The purpose of this article is to discuss (1) the objectives of "Reaching Asian Americans through Innovative and Supportive Engagement," (RAISE) a multisector coalition (2) describe the process in which the coalition was engaged in, and (3) share lessons learned that can inform future partnerships with various sectors that reach AAPI communities that are highly diverse and in geographically dispersed areas...
2017: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29050889/nine-point-plan-to-improve-care-of-the-injured-patient-a-case-study-from-kenya
#13
Abdulgafoor M Bachani, Isaac Botchey, Fatima Paruk, Daniel Wako, Hassan Saidi, Bethuel Aliwa, Simon Kibias, Adnan A Hyder
BACKGROUND: Injury rates in low- and middle-income countries are among the greatest in the world, with >90% of unintentional injury occurring in low- or middle-income countries. The risk of death from injuries is 6 times more in low- and middle-income countries than in high-income countries. This increased rate of injury is partly due to the lack of availability and access to timely and appropriate medical care for injured individuals. Kenya, like most low- and middle-income countries, has seen a 5-fold increase in injury fatalities throughout the past 4 decades, in large part related to the absence of a coordinated, integrated system of trauma care...
October 16, 2017: Surgery
https://www.readbyqxmd.com/read/29043084/multi-species-genetic-connectivity-in-a-terrestrial-habitat-network
#14
Robby R Marrotte, Jeff Bowman, Michael G C Brown, Chad Cordes, Kimberley Y Morris, Melanie B Prentice, Paul J Wilson
BACKGROUND: Habitat fragmentation reduces genetic connectivity for multiple species, yet conservation efforts tend to rely heavily on single-species connectivity estimates to inform land-use planning. Such conservation activities may benefit from multi-species connectivity estimates, which provide a simple and practical means to mitigate the effects of habitat fragmentation for a larger number of species. To test the validity of a multi-species connectivity model, we used neutral microsatellite genetic datasets of Canada lynx (Lynx canadensis), American marten (Martes americana), fisher (Pekania pennanti), and southern flying squirrel (Glaucomys volans) to evaluate multi-species genetic connectivity across Ontario, Canada...
2017: Movement Ecology
https://www.readbyqxmd.com/read/29035572/maintaining-and-enhancing-diversity-of-sampled-protein-conformations-in-robotics-inspired-methods
#15
Jayvee R Abella, Mark Moll, Lydia E Kavraki
The ability to efficiently sample structurally diverse protein conformations allows one to gain a high-level view of a protein's energy landscape. Algorithms from robot motion planning have been used for conformational sampling, and several of these algorithms promote diversity by keeping track of "coverage" in conformational space based on the local sampling density. However, large proteins present special challenges. In particular, larger systems require running many concurrent instances of these algorithms, but these algorithms can quickly become memory intensive because they typically keep previously sampled conformations in memory to maintain coverage estimates...
October 16, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29032849/mapping-the-landscape-of-patient-centric-activities-within-clinical-research
#16
Mary Jo Lamberti, Josephine Awatin
PURPOSE: Although there has been more involvement by patients in the drug-development process, there are not a lot of published data that quantify patient-centric activities or that document these activities across a large scale. In order to examine the patient-centricity landscape and to quantify the adoption and implementation of these initiatives, the Tufts Center for the Study of Drug Development and the Drug Information Association collaborated on a research study. The study examined patient-centric activities implemented by pharmaceutical, biotechnology, and contract research organizations, as well as activities being piloted or in the planning stages...
October 9, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29030630/ecosystem-carbon-storage-in-forest-fragments-of-differing-patch-size
#17
Lei Ma, Chunyu Shen, Duo Lou, Shenglei Fu, Dongsheng Guan
Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density. Allometric equations were used to quantify aboveground biomass. Carbon density was estimated by analyzing the C concentration of each component. We found that ecosystem carbon density ranged from 173...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29018528/correction-evaluation-of-the-current-landscape-of-respiratory-nurse-specialists-in-the-uk-planning-for-the-future-needs-of-patients
#18
(no author information available yet)
[This corrects the article DOI: 10.1136/bmjresp-2017-000210.][This corrects the article DOI: 10.1136/bmjresp-2017-000210.].
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28991683/a-new-pla2g6-mutation-in-a-family-with-infantile-neuroaxonal-dystrophy
#19
Iannello Grazia, Graziano Claudio, Cenacchi Giovanna, Cordelli Duccio Maria, Zuntini Roberta, Papa Valentina, Magistà Anna Maria, Gagliardi Monica, Procopio Radha, Quattrone Aldo, Annesi Grazia
Phospholipase A2-associated neurodegeneration (PLAN), a syndrome of Neurodegeneration with Brain Iron Accumulation (NBIA), is an autosomal recessive disorder caused by mutations in PLA2G6 gene. This gene encodes a calcium-independent group VI phospholipase A2 (iPLA-VI) critical in cell membrane homeostasis. PLAN syndrome encompasses a group of phenotypes with a different age of onset: classic infantile neuroaxonal dystrophy (INAD), atypical neuroaxonal dystrophy of childhood-onset (atypical NAD) and adult-onset PLA2G6-related dystonia-parkinsonism (PARK14)...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28968680/management-of-arthropod-pathogen-vectors-in-north-america-minimizing-adverse-effects-on-pollinators
#20
Howard S Ginsberg, Timothy A Bargar, Michelle L Hladik, Charles Lubelczyk
Tick and mosquito management is important to public health protection. At the same time, growing concerns about declines of pollinator species raise the question of whether vector control practices might affect pollinator populations. We report the results of a task force of the North American Pollinator Protection Campaign (NAPPC) that examined potential effects of vector management practices on pollinators, and how these programs could be adjusted to minimize negative effects on pollinating species. The main types of vector control practices that might affect pollinators are landscape manipulation, biocontrol, and pesticide applications...
November 7, 2017: Journal of Medical Entomology
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