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joint space narrowing in osteoarthritis

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https://www.readbyqxmd.com/read/29287118/serum-n-propeptide-of-collagen-iia-piianp-as-a-marker-of-radiographic-osteoarthritis-burden
#1
Hikmat N Daghestani, Joanne M Jordan, Jordan B Renner, Michael Doherty, A Gerry Wilson, Virginia B Kraus
OBJECTIVE: Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a biomarker representing type II collagen synthesis, in osteoarthritis. METHODS: OA burden was quantified on the basis of radiographic features as total joint faces with an osteophyte, joint space narrowing, or in the spine, disc space narrowing...
2017: PloS One
https://www.readbyqxmd.com/read/29246142/association-between-metabolic-syndrome-and-knee-osteoarthritis-a-cross-sectional-study
#2
Dong-Xing Xie, Jie Wei, Chao Zeng, Tuo Yang, Hui Li, Yi-Lun Wang, Hui-Zhong Long, Zi-Ying Wu, Yu-Xuan Qian, Kang-Hua Li, Guang-Hua Lei
BACKGROUND: Osteoarthritis (OA) is the most prevalent chronic joint disease in China. The aim of this study was to examine the association between metabolic syndrome (MetS) and knee OA in a population-based Chinese study. METHODS: Data included in this analysis is from a cross-sectional study, i.e., the Xiangya Hospital Health Management Center Study. MetS was diagnosed according to the criteria defined by the Chinese Diabetes Society. Radiographic knee OA was defined as changes equivalent to Kellgren-Lawrence (K-L) grade 2 or above at least one side...
December 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29202806/risk-factors-for-joint-replacement-in-knee-osteoarthritis-a-15-year-follow-up-study
#3
Flemming K Nielsen, Niels Egund, Anette Jørgensen, Anne Grethe Jurik
BACKGROUND: To evaluate whether clinical, radiographic or MRI findings are associated with long term risk for total knee arthroplasty (TKA) in persons with knee osteoarthritis. METHODS: We performed a follow-up analysis of 100 persons with knee osteoarthritis who participated in a clinical trial between 2000 and 2002. Clinical data as well as radiography and MRI of the inclusion knee were obtained in all participants. Data on TKA procedures were extracted from The Danish National Patient Register...
December 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29202561/meniscal-extrusion-as-booster-of-osteoarthritis
#4
R Papalia, G Papalia, F Russo, L A Diaz, F Bressi, S Sterzi, V Denaro
Meniscal extrusion (ME) has shown to play a critical but still unclear role in osteoarthritis (OA) development. ME has been described as an important risk factor in the progression of knee OA, as it is involved in the thinning of articular cartilage, joint space narrowing, spontaneous osteonecrosis of the knee and subchondral bone marrow lesions. Meniscal damage of any degree of severity could cause ME in both compartments, but it is commonly associated with severe meniscal tears or root tears mainly in the medial meniscus...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29190722/association-between-grip-strength-and-hand-and-knee-radiographic-osteoarthritis-in-korean-adults-data-from-the-dong-gu-study
#5
Lihui Wen, Min-Ho Shin, Ji-Hyoun Kang, Yi-Rang Yim, Ji-Eun Kim, Jeong-Won Lee, Kyung-Eun Lee, Dong-Jin Park, Tae-Jong Kim, Sun-Seog Kweon, Young-Hoon Lee, Yong-Woon Yun, Shin-Seok Lee
OBJECTIVES: We assessed whether grip strength was related to various types of radiographic damage in Korean adults with osteoarthritis (OA). METHODS: Data from 2,251 subjects enrolled in the Dong-gu study, who had no hand joint pain, were analyzed to investigate the relationship between grip strength and OA. Hand grip strength was measured using a hand-held dynamometer, and radiographs of the hand and knee were scored according to a semi-quantitative grading system...
2017: PloS One
https://www.readbyqxmd.com/read/29164284/uncommon-observation-of-bifocal-giant-subchondral-cysts-in-the-hip-diagnostic-role-of-ct-arthrography-and-mri-with-pathological-correlation
#6
Pauline Gonzalez-Espino, Maïté Van Cauter, Louis Gossing, Christine C Galant, Souad Acid, Frederic E Lecouvet
Subchondral cysts (or geodes) are common in osteoarthritis (OA), usually in association with other typical signs, i.e., joint space narrowing, subchondral bone sclerosis, and osteophytosis. However, large lesions without the typical signs of OA or lesions located outside the weight-bearing areas are unusual and may be confused for other conditions, in particular, those of tumoral origin. We report the findings in a 48-year-old man who had been complaining of left buttock pain for 3 years, getting worse over the last year, and an evolutive limited range of motion of the hip...
November 21, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29159676/the-posterior-anterior-flexed-view-is-better-than-the-anterior-posterior-view-for-assessing-osteoarthritis-of-the-knee
#7
Kilian Rueckl, Friedrich Boettner, Noor Maza, Armin Runer, Ulrich Bechler, Peter Sculco
OBJECTIVE: The aim of this study is to determine whether the posterior-anterior (PA)-flexed view improves the radiographic assessment of patients with knee pain compared with the standard standing anterior-posterior radiograph. MATERIALS AND METHODS: Three hundred and sixty-five patients with knee pain underwent anterior-posterior (AP), PA flexed, lateral, and Merchant radiographs of the knee. Knees were grouped as mild (Kellgren and Lawrence [K-L] 1-2) or severe (K-L 3-4) osteoarthritis (OA) and either varus (medial compartment), valgus (lateral compartment), or patellofemoral OA...
November 20, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29037516/statin-use-and-knee-osteoarthritis-progression-results-from-a-post-hoc-analysis-of-the-sekoia-trial
#8
Florent Eymard, Camille Parsons, Mark H Edwards, Florence Petit-Dop, Jean-Yves Reginster, Olivier Bruyère, Xavier Chevalier, Cyrus Cooper, Pascal Richette
OBJECTIVE: Epidemiological and experimental studies have suggested that lipid disorders might be involved in the pathophysiology of knee osteoarthritis (OA). Studies assessing the effect of statins on knee OA progression have shown conflicting results. We investigated the impact of statin use on radiological progression in patients with radiological and symptomatic knee OA. METHODS: 336 patients from the placebo arm of SEKOIA trial completed the 3-year follow-up and were included in this post-hoc analysis...
October 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28976494/objectively-measured-physical-activity-and-risk-of-knee-osteoarthritis
#9
Jin Qin, Kamil E Barbour, Michael C Nevitt, Charles G Helmick, Jennifer M Hootman, Louise B Murphy, Jane A Cauley, Dorothy D Dunlop
PURPOSE: To examine the association between objectively measured physical activity and risk of developing incident knee osteoarthritis (OA) in a community-based cohort of middle-aged and older adults. METHODS: We used data from the Osteoarthritis Initiative (OAI), an ongoing prospective cohort study of adults aged 45 to 83 at initial enrollment with elevated risk of symptomatic knee OA. Moderate-vigorous physical activity (MVPA) was measured by a uniaxial accelerometer for seven continuous days in two data collection cycles, and was categorized as inactive (<10 minutes/week), low activity (10-<150 minutes/week), and active (≥150 minutes/week)...
October 2, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28941552/race-sex-and-risk-factors-in-radiographic-worsening-of-knee-osteoarthritis
#10
Ernest R Vina, Di Ran, Erin L Ashbeck, Charles Ratzlaff, C Kent Kwoh
OBJECTIVES: Characterize radiographic worsening in knee osteoarthritis (KOA) by race and sex over 4 years and evaluate the role of established risk factors in observed race/sex differences. METHODS: Whites (WHs) (694 males and 929 females) and African-Americans (AAs) (92 males and 167 females) at risk for radiographic KOA were eligible. Cox shared frailty models were used to estimate race and sex group differences in radiographic worsening, defined by Kellgren-Lawrence (K-L) and OARSI joint space narrowing (JSN)...
August 31, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28935435/subchondral-tibial-bone-texture-predicts-the-incidence-of-radiographic-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#11
T Janvier, R Jennane, H Toumi, E Lespessailles
OBJECTIVES: To evaluate whether trabecular bone texture (TBT) parameters measured on computed radiographs (CR) could predict the onset of radiographic knee osteoarthritis (OA). MATERIALS AND METHODS: Subjects from the Osteoarthritis Initiative (OAI) with no sign of radiographic OA at baseline were included. Cases that developed either a global radiographic OA defined by the Kellgren-Lawrence (KL) scale, a joint space narrowing (JSN) or tibial osteophytes (TOS) were compared with the controls with no changes after 48 months of follow-up...
September 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28934632/in-vivo-biomechanical-behavior-of-the-trapeziometacarpal-joint-in-healthy-and-osteoarthritic-subjects
#12
Priscilla D'Agostino, Benjamin Dourthe, Faes Kerkhof, G Harry Van Lenthe, Filip Stockmans, Evie E Vereecke
BACKGROUND: The contact biomechanics of the trapeziometacarpal joint have been investigated in several studies. However, these led to conflicting results and were mostly performed in vitro. The purpose of this study was to provide further insight on the contact biomechanics of the trapeziometacarpal joint by in vivo assessment of healthy and osteoarthritic subjects. METHODS: The hands of 16 healthy women and 6 women with trapeziometacarpal osteoarthritis were scanned in positions of maximal thumb extension, flexion, abduction and adduction during three isometric tasks (lateral key pinch, power grasp and jar twist) and in thumb rest posture (relaxed neutral)...
September 12, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28920170/meniscal-extrusion-seen-on-ultrasonography-affects-the-development-of-radiographic-knee-osteoarthritis-a-3-year-prospective-cohort-study
#13
Daisuke Chiba, Shugo Maeda, Eiji Sasaki, Seiya Ota, Shigeyuki Nakaji, Eiichi Tsuda, Yasuyuki Ishibashi
The objective of this study is to determine whether meniscal extrusion (ME) of the medial meniscus on ultrasonography affects knee osteoarthritis (KOA) progression during 3-year follow-up. Two hundred seventy volunteers (70 men, 200 women; mean age 60.5 years) participated. Weight-bearing radiographs were evaluated. All subjects had medial radiographic KOA (Kellgren-Lawrence grade [KLG], ≥ 2) in at least one knee at baseline (BL). KLG 2 was defined as moderate KOA (MKOA); KLG 3 and 4 were defined as severe KOA (SKOA)...
November 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28918594/the-association-of-knee-structural-pathology-with-pain-at-the-knee-is-modified-by-pain-at-other-sites-in-those-with-knee-osteoarthritis
#14
Feng Pan, Jing Tian, Dawn Aitken, Flavia Cicuttini, Tania Winzenberg, Graeme Jones
The objective of this study was to investigate the associations of knee structural abnormalities with different patterns of pain. A total of 891 participants (average age 63 years; range 50 to 80 years) participated in this study. Presence of pain at the neck, back, hands, shoulders, hips, knees, and feet was assessed by questionnaire. Participants were categorized as having no pain at any site (no pain), pain only at the knee (KP), pain at other sites but not the knee (OP), and pain at the knee and other sites (KOP)...
November 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28882362/independent-association-of-joint-space-narrowing-cyst-formation-and-health-related-quality-of-life-of-patients-with-hip-osteoarthritis-in-japan
#15
Yasuhiko Takegami, Taisuke Seki, Yoshitoshi Higuchi, Daigo Komatsu, Yoshihiro Nishida, Naoki Ishiguro
INTRODUCTION: This study clarified individual associations of joint space narrowing (JSN) and radiographic features (RF) of hip osteoarthritis (HOA), i.e., cyst and osteophyte formation and subchondral sclerosis, with quality of life (QOL) in Japanese HOA patients. METHODS: This cross-sectional study comprised 117 Japanese HOA patients (98 women, 17 men; mean age, 61.2 years). We recorded locations and the size of each RF and measured JSN on the acetabular side (Ace) or femoral head (FH)...
September 4, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28879056/ultrasound-detected-osteophytes-predict-the-development-of-radiographic-and-clinical-features-of-hand-osteoarthritis-in-the-same-finger-joints-5-years-later
#16
Alexander Mathiessen, Barbara Slatkowsky-Christensen, Tore K Kvien, Ida K Haugen, Hilde Berner Hammer
BACKGROUND: Structural pathology may be present in joints without radiographic evidence of osteoarthritis (OA). Ultrasound is a sensitive tool for early detection of osteophytes. Our aim was to explore whether ultrasound-detected osteophytes (in radiographically and clinically normal finger joints) predicted the development of radiographic and clinical hand OA 5 years later. METHODS: We included finger joints without radiographic OA (Kellgren-Lawrence grade (KLG)=0; n=301) or no clinical bony enlargements (n=717) at baseline and examined whether ultrasound-detected osteophytes predicted incident radiographic OA (KLG ≥1, osteophytes or joint space narrowing (JSN)) or incident clinical bony enlargement (dependent variables) in the same joints 5 years later...
2017: RMD Open
https://www.readbyqxmd.com/read/28864651/associations-between-knee-effusion-synovitis-and-joint-structural-changes-in-patients-with-knee-osteoarthritis
#17
Xia Wang, Xingzhong Jin, Leigh Blizzard, Benny Antony, Weiyu Han, Zhaohua Zhu, Flavia Cicuttini, Anita E Wluka, Tania Winzenberg, Graeme Jones, Changhai Ding
OBJECTIVE: To describe the associations between effusion-synovitis and joint structural abnormalities in patients with knee osteoarthritis (OA) over 24 months. METHODS: A posthoc analysis using data from a randomized controlled trial in 413 patients with symptomatic OA (aged 63 ± 7 yrs, 208 women). Knee effusion-synovitis volume and score, cartilage defects, cartilage volume, and bone marrow lesions (BML) were assessed using magnetic resonance imaging. Joint space narrowing (JSN) and osteophytes were assessed using radiograph...
November 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28832198/joint-space-narrowing-in-patients-with-pisotriquetral-osteoarthritis
#18
Paul W L Ten Berg, Erik Heeg, Simon D Strackee, Geert J Streekstra
BACKGROUND: Patients with suspected pisotriquetral osteoarthritis may show joint space narrowing. However, the extent of joint space narrowing and its deviation from the joint space width (JSW) in normal anatomy is unknown. In this pathoanatomic study, we therefore compared the JSW in the pisotriquetral joint between osteoarthritic patient wrists and healthy wrists. METHODS: We reviewed preoperative computed tomography (CT) scans of 8 wrists of patients with ulnar-sided wrist pain who underwent a pisiformectomy with confirmed pisotriquetral osteoarthritis at surgery...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28828181/peri-talar-re-alignment-osteotomy-for-joint-preservation-in-asymmetrical-ankle-osteoarthritis
#19
REVIEW
Young Yi, Woochun Lee
Various types of re-alignment surgery are used to preserve the ankle joint in cases of intermediate ankle arthritis with partial joint space narrowing.The short-term and mid-term results after re-alignment surgery are promising, with substantial post-operative pain relief and functional improvement that is reflected by high rates of patient satisfaction.In this context, re-alignment surgery can preserve the joint and reduce the pathological load that acts on the affected area.Good clinical and radiological outcomes can be achieved in asymmetrical ankle osteoarthritis by understanding the specific deformities and appropriate indications for different surgical techniques...
July 2017: EFORT Open Reviews
https://www.readbyqxmd.com/read/28822670/peritrapezial-osteoarthritis-inter-and-intraobserver-reliability-of-the-allieu-classification
#20
F Vigouroux, F Rabarin, J Jeudy, N Bigorre, Y Saint Cast, L Pechmajou, G Raimbeau
The Allieu classification takes into consideration the distal and proximal joints of the trapezium. Trapeziometacarpal (TMC) joint arthritis, TMC joint instability (TMI) and scapho-trapezio-trapezoid (STT) joint arthritis are considered independently, which better corresponds to the anatomical examinations. The aim of the study was to evaluate the inter- and intraobserver reliability of the Allieu classification of the peritrapezial arthritis. This was a prospective, single-center study performed from May to September 2016 with 30 cases of primary thumb osteoarthritis...
October 2017: Hand Surgery and Rehabilitation
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