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Jan Bonhoeffer, Sonali Kochhar, Steven Hirschfeld, Paul T Heath, Christine E Jones, Jorgen Bauwens, Ángel Honrado, Ulrich Heininger, Flor M Muñoz, Linda Eckert, Mark Steinhoff, Steven Black, Michael Padula, Miriam Sturkenboom, Jim Buttery, Robert Pless, Patrick Zuber
Immunization in pregnancy provides a promising contribution to globally reducing neonatal and under-five childhood mortality and morbidity. Thorough assessment of benefits and risks for the primarily healthy pregnant women and their unborn babies is required. The GAIA project was formed in response to the call of the World Health Organization for a globally concerted approach to actively monitor the safety of vaccines and immunization in pregnancy programs. GAIA aims to improve the quality of outcome data from clinical vaccine trials in pregnant women with a specific focus on the needs and requirements for safety monitoring in LMIC...
October 14, 2016: Vaccine
Ellen Brady, Julia Segar, Caroline Sanders
BACKGROUND: The ethics of research into online communities is a long-debated issue, with many researchers arguing that open-access discussion groups are publically accessible data and do not require informed consent from participants for their use for research purposes. However, it has been suggested that there is a discrepancy between the perceived and actual privacy of user-generated online content by community members. OBJECTIVE: There has been very little research regarding how privacy is experienced and enacted online...
October 13, 2016: Journal of Medical Internet Research
Priya Sahadeo, Robert J Weber
On March 28, 2014, The United States Pharmacopeia and The National Formulary (USP-NF) published USP General Chapter <800> Hazardous Drugs-Handling in Healthcare Settings, as open for public comment in the USP Pharmacopeial Forum (PF) 40(3). Pharmacy directors must be proactive in understanding the impact that USP <800> will have on their processes for preparing sterile products. USP General Chapter <797> pertains to the compounding of both hazardous and nonhazardous drugs. USP <800> serves as a new standard to guide the handling of hazardous drugs in order to protect patients, health care personnel, and the environment...
November 2015: Hospital Pharmacy
Nam-Gyu Park
Since the groundbreaking report on a solid-state perovskite solar cell employing a methylammonium lead iodide-sensitized mesoporous TiO2 film and an organic hole conducting layer in 2012 by our group, the swift surge of perovskite photovoltaics opens a new paradigm in solar-cell research. As a result, ca. 1300 peer-reviewed research articles were published in 2015. In this Inorganic Chemistry Forum on Halide Perovskite, the researches with highlights of work on perovskite solar cells in my laboratory are reviewed...
October 6, 2016: Inorganic Chemistry
Clare Dolman, Ian R Jones, Louise M Howard
BACKGROUND: Women with bipolar disorder are at increased risk of having a severe episode of illness associated with childbirth. AIMS: To explore the factors that influence the decision-making of women with bipolar disorder regarding pregnancy and childbirth. METHOD: Qualitative study with a purposive sample of women with bipolar disorder considering pregnancy, or currently or previously pregnant, supplemented by data from an online forum. Data were analysed using thematic analysis...
September 2016: BJPsych Open
Todd D Little, Kathleen M Roche, Sy-Miin Chow, Anna P Schenck, Leslie-Ann Byam
The National Institutes of Health (NIH) Pathways to Prevention Workshop "Advancing Research to Prevent Youth Suicide" was cosponsored by the NIH Office of Disease Prevention, National Institute of Mental Health, National Institute on Drug Abuse, and National Center for Complementary and Integrative Health. A multidisciplinary working group developed the agenda, and an evidence-based practice center prepared an evidence report that addressed data systems relevant to suicide prevention efforts through a contract with the Agency for Healthcare Research and Quality...
October 4, 2016: Annals of Internal Medicine
Sarah Jackson
We are delighted to publish the first set of articles in JCI Insight, the newest peer-reviewed publication of the American Society for Clinical Investigation (ASCI), a nonprofit honor society for physician-scientists. In creating this journal, we sought to provide an expanded forum for a wide range of preclinical, translational, and clinical research that uncovers new insights into the basis of disease and therapeutic approaches. In selecting articles for JCI Insight, we place a strong emphasis on rigorous experimental methods and data reporting, which are truly the hallmark of publications in the JCI family...
January 21, 2016: JCI Insight
Gordon Lee Gillespie, Tracy Pritchard, Karen Bankston, Jasmine Burno, Greer Glazer
BACKGROUND: The lack of diversity in the nursing profession could be an outcome of unconscious biases. Forums allowing the personal reflection and discourse of these unconscious biases are needed in order for a diverse and inclusive learning environment to exist. PURPOSE: The purpose of this study was to describe the experiences of students, staff, faculty members, and guests participating in a forum on diversity and inclusion. METHODS: An exploratory design was used to understand the experiences of college of nursing students, staff, faculty members, and guests who participated in a diversity and inclusion intervention sponsored by the college of nursing's Diversity Advisory Council...
August 30, 2016: Nursing Outlook
Erik C Burns, Jeff Moran, Sheila Breidinger, Stacy Ho, Randy Guthrie, Lakshmi Amaravardi
17th Annual Land O'Lakes Bioanalytical Conference, Madison, WI, USA, 11-14 July 2016 The 17th Annual Land O'Lakes Bioanalytical Conference, titled 'Biomarker Validation, Stability, and Regulatory Concerns', was held on 11-14 July 2016 (Monday through Thursday) in Madison, WI, USA. The Land O'Lakes Conference is presented each year by the Division of Pharmacy Professional Development within the School of Pharmacy at the University of Wisconsin-Madison (USA). The purpose of this 3-day conference is to provide an educational forum to discuss issues and applications associated with the analysis of xenobiotics, metabolites, biologics and biomarkers in biological matrices...
November 2016: Bioanalysis
Claudia Rouse, Punam Mistry, Oli Rayner, Jess Nickless, Mandy Wan, Kevin W Southern, Hannah K Batchelor
BACKGROUND: The palatability of flucloxacillin oral liquid is poor. Parents/carers use strategies to aid the administration of poorly palatable medicines. AIM: To assess views on the palatability of flucloxacillin oral liquid and identify factors associated with successful administration. METHODS: A mixed methods study which included a structured review of online forums and a survey of parent/carers of children with cystic fibrosis (CF) to obtain parent/carer views on the administration of flucloxacillin oral liquid...
September 16, 2016: International Journal of Pharmacy Practice
Amity E Quinn, Anna D Rubinsky, Anne C Fernandez, Hyeouk Chris Hahm, Jeffrey H Samet
The separation of addiction care from the general medical care system has a negative impact on patients' receipt of high-quality medical care. Clinical and policy-level strategies to improve the coordination of addiction care and general medical care include identifying and engaging patients with unhealthy substance use in general medical settings, providing effective chronic disease management of substance use disorders in primary care, including patient and family perspectives in care coordination, and implementing pragmatic models to pay for the coordination of addiction and general medical care...
September 15, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
David V Gauvin, Zachary J Zimmermann, Mary Jeanne Kallman
BACKGROUND: The Controlled Substances Staff of the Center for Drug Evaluation and Research at the US Food and Drug Administration and the Pharmaceutical Research Manufacturers Association (PhRMA) conducted a series of open forum dialog sessions between 2006 and 2016. A Cross Company Abuse Liability Council (CCALC) was formed during the process of this unique collaborative effort between Industry and Federal Regulators whose goals were to establish the development of standards for the preclinical screening of new molecular entities for schedule control actions required as part of every New Drug Application process...
August 13, 2016: Drug and Alcohol Dependence
Laura Sampietro-Colom, Sarah Thomas
The need to progress and innovate in health technology assessment (HTA) is a must in a continuously changing environment. The HTAi Policy Forum reflected on two specific areas for development where it was thought there was need for careful consideration and deliberation during the main annual meeting in February 2016. The study by Husereau et al. (1) in this journal presents the discussions resulting from this Forum. To further share the deliberations of the Forum and with a view to opening this debate to the wider HTA community, a panel session during the HTAi Annual Meeting in Tokyo was organized...
September 14, 2016: International Journal of Technology Assessment in Health Care
Takahiro Nakamura
Tower Hall Funabori, Tokyo, Japan, 9-10 March 2016 At the 7th Japan Bioanalysis Forum symposium, bioanalytical methods and processes were discussed with authorities after the issuing of bioanalytical method validation guidelines (EMA and Japanese Ministry of Health, Labour and Welfare) and draft guidance (US FDA). Method establishment and bioanalysis of biomarkers were discussed with a focus on scientific validation. Bioanalytical methods for antibody-drug conjugates, the potential of MS imaging and microsampling activity in drug development were introduced...
October 2016: Bioanalysis
Richard Schilsky, Will Davies
The Worldwide Innovative Networking (WIN) consortium is an alliance of academic institutions, pharmaceutical partners, representatives from technology companies and charitable/health payer organisations from across the globe. For the last six years, the consortium's aims have been to foster communication and collaboration between members, encourage dialogue in an open forum, and deliver clinical trial results that improve the care and outcomes of patients with cancer using the latest advances in genomic-based medicine...
2016: Ecancermedicalscience
Paraag Trivedi, Nicola Rosaasen, Holly Mansell
CONTEXT: Adequate patient education is essential for preparing potential recipients for kidney transplantation. Health-care providers play a vital role in education and can identify gaps in patient understanding. OBJECTIVE: To identify deficits in patient knowledge from the perspective of a transplant multidisciplinary care team and determine whether their perceptions align with patients who have previously undergone a transplant. DESIGN: An open call was advertised for health-care providers to attend a focus group discussion regarding the educational needs of pretransplant patients in 1 Canadian center...
August 22, 2016: Progress in Transplantation
Andrew Taylor, Adam Sutherland
INTRODUCTION: Clinical supervision is defined by Barber and Norman as having four main functions: educational, supportive, managerial and development of self-awareness.1 It is common practice within initial pharmacy education for clinical supervision to take place at undergraduate, pre-registration and foundation level pharmacist stages. But what about the specialist trainees? It is probably a fair observation that the amount of clinical supervision provided for pharmacists undergoing their advanced level practice drops vividly...
September 2016: Archives of Disease in Childhood
Bevin Croft, Kaipeng Wang, Benjamin Cichocki, Anne Weaver, Kevin Mahoney
Self-direction has emerged worldwide as a promising practice for persons with serious mental health conditions and as a means toward creating more person-centered service systems. In self-direction, service users control an individualized budget, purchasing goods or services that can help them achieve personal recovery goals. This Open Forum describes an international learning exchange meeting, held in September 2015, in which experts in self-direction and mental health from seven nations convened for sharing best practices, discussing challenges, and laying the groundwork for a learning community to support the continued development of self-direction...
August 15, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
Joseph M Cerimele, John C Fortney, Jürgen Unützer
This Open Forum addresses considerations for improving treatment of bipolar disorder. Most individuals with bipolar disorder report not receiving treatment from a psychiatrist in the past 12 months. In the United States, a large proportion of persons with bipolar disorder seek treatment in primary care. These patients have high symptom severity and functional impairment but are less likely to receive mood-stabilizing medications. In a prior study in a primary care setting, the authors found that one-third of patients with bipolar disorder improved after receiving treatment in primary care in a statewide collaborative care program...
August 15, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
Mustafa Karakus, Sushmita Shoma Ghose, Howard H Goldman, Garrett Moran, Michael F Hogan
The purpose of this Open Forum is to highlight strategies that can be implemented by federal health care policy makers to improve the delivery of effective behavioral health care services in the public and private sectors. The recommendations can be accomplished by using existing funds or authorities allocated to federal agencies dealing with the behavioral health system. These recommendations do not require new or additional funding and focus on strategies with a track record for success. The strategies described require relatively small changes but have the potential for big impacts...
August 15, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
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