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https://www.readbyqxmd.com/read/28215998/photosensitivity-in-generalized-epilepsies
#1
REVIEW
Shervonne Poleon, Jerzy P Szaflarski
Photosensitivity, which is the hallmark of photosensitive epilepsy (PSE), is described as an abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The PPR is a well-recognized phenomenon, occurring in 2-14% of patients with epilepsy but its pathophysiology is not clearly understood. PPR is electrographically described as 2-5Hz spike, spike-wave, or slow wave complexes with frontal and paracentral prevalence. Diagnosis of PPR is confirmed using intermittent photic stimulation (IPS) as well as video monitoring...
February 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28197802/effects-of-vaccine-acquired-polyclonal-anti-hbs-antibodies-on-the-prevention-of-hbv-infection-of-non-vaccine-genotypes
#2
Masaki Kato, Susumu Hamada-Tsutsumi, Chiaki Okuse, Aiko Sakai, Nobuyuki Matsumoto, Masaaki Sato, Toshiyuki Sato, Mitsumi Arito, Kazuki Omoteyama, Naoya Suematsu, Kazuki Okamoto, Takanobu Kato, Fumio Itoh, Ryo Sumazaki, Yasuhito Tanaka, Hiroshi Yotsuyanagi, Tomohiro Kato, Manae Suzuki Kurokawa
BACKGROUND: In universal hepatitis B (HB) vaccination, single vaccine-derived polyclonal anti-HBs antibodies (anti-HBs) need to inhibit infection of HB viruses (HBV) of non-vaccine genotypes. We experimentally addressed this issue. METHODS: Anti-HBs-positive sera were obtained by vaccination with genotype A- or C-derived HBs antigen (HBsAg, gtA-sera or gtC-sera). Their reactivity to genotype A- and C-derived HBsAg (gtA-Ag and gtC-Ag) was measured by ELISA. The capacity of sera to neutralize HBV was evaluated using an in vitro infection model...
February 14, 2017: Journal of Gastroenterology
https://www.readbyqxmd.com/read/28062751/transcriptome-wide-mapping-of-rna-5-methylcytosine-in-arabidopsis-mrnas-and-non-coding-rnas
#3
Rakesh David, Alice Burgess, Brian Parker, Jun Li, Kalinya Pulsford, Tennille Sibbritt, Thomas Preiss, Iain R Searle
Post-transcriptional methylation of RNA cytosine residues to 5-methylcytosine (m5C) is an important modification with diverse roles, such as regulating stress responses, stem cell proliferation, and RNA metabolism. Here, we used RNA bisulfite sequencing (bsRNA-seq) for transcriptome-wide quantitative mapping of m5C in the model plant, Arabidopsis thaliana. We discovered more than a thousand m5C sites in Arabidopsis mRNAs, long non-coding RNAs, and other non-coding RNAs across three tissue types (siliques, seedling shoots, and roots) and validated a number of these sites...
January 6, 2017: Plant Cell
https://www.readbyqxmd.com/read/27995874/brevundimonas-balnearis-sp-nov-isolated-from-the-well-water-of-a-thermal-bath
#4
Erika Tóth, Sára Szuróczki, Zsuzsa Kéki, Judit Kosztik, Judit Makk, Károly Bóka, Cathrin Spröer, Károly Márialigeti, Peter Schumann
A novel Alphaproteobacterium was isolated from the well water of a thermal bath at Budapest, Hungary. Phylogenetic analysis of the new strain showed that this bacterium belongs to a distinct lineage among the genus Brevundimonas. Based on the 16S rRNA gene sequence strain FDRGB2bT shows the highest sequence similarity values to Brevundimonas naejangsanensis BIO-TAS2-2T (97.35%), Brevundimonas viscosa F3T (97.28%), Brevundimonas vesicularis LMG 2350T (97.27%), Brevundimonas nasdae GTC 1043T (97.14%), Brevundimonas vancanneytii LMG 2337T (97...
December 20, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27966250/continuous-soil-carbon-storage-of-old-permanent-pastures-in-amazonia
#5
Clément Stahl, Sébastien Fontaine, Katja Klumpp, Catherine Picon-Cochard, Marcia Mascarenhas Grise, Camille Dezécache, Lise Ponchant, Vincent Freycon, Lilian Blanc, Damien Bonal, Benoit Burban, Jean-François Soussana, Vincent Blanfort
Amazonian forests continuously accumulate carbon (C) in biomass and in soil, representing a carbon sink of 0.42-0.65 GtC yr(-1) . In recent decades, more than 15% of Amazonian forests have been converted into pastures, resulting in net C emissions (~200 tC ha(-1) ) due to biomass burning and litter mineralization in the first years after deforestation. However, little is known about the capacity of tropical pastures to restore a C sink. Our study shows in French Amazonia that the C storage observed in native forest can be partly restored in old (≥24 year) tropical pastures managed with a low stocking rate (±1 LSU ha(-1) ) and without the use of fire since their establishment...
December 14, 2016: Global Change Biology
https://www.readbyqxmd.com/read/27957468/hashimoto-encephalopathy-with-an-unusual-presentation-of-status-epilepticus-seizures-a-case-report
#6
Masoume Nazeri, Amin Abolhasani Foroughi, Hora Heidari, Sarvin Sajadianfard, Tannaz Eghbali, Peyman Arasteh
A 33 yr old man, previously diagnosed with hypothyroidism, presented with decreased level of consciousness and generalized tonic-clonic (GTC) seizure to Namazi hospital, Shiraz, Iran, during April 2015. The patient later referred with another episode of seizure like attack for which he received phenytoin, carbamazepine and levothyroxine and was discharged. During his last admission, the patient was admitted with chief complaints of decreased consciousness and four GTC attacks. On admission, the patients had aphasia, ataxia, loss of verbal communication, eye contact and complete loss of obedience...
September 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27910444/synthetic-diagnostics-platform-for-fusion-plasmas-invited
#7
L Shi, E J Valeo, B J Tobias, G J Kramer, L Hausammann, W M Tang, M Chen
A Synthetic Diagnostics Platform (SDP) for fusion plasmas has been developed which provides state of the art synthetic reflectometry, beam emission spectroscopy, and Electron Cyclotron Emission (ECE) diagnostics. Interfaces to the plasma simulation codes GTC, XGC-1, GTS, and M3D-C(1) are provided, enabling detailed validation of these codes. In this paper, we give an overview of SDP's capabilities, and introduce the synthetic diagnostic modules. A recently developed synthetic ECE Imaging module which self-consistently includes refraction, diffraction, emission, and absorption effects is discussed in detail...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27906473/tensile-comparison-of-polydioxanone-polyglyconate-and-barbed-glycolide-trimethylene-carbonate-suture-in-canine-cadaveric-tensor-fascia-lata
#8
Naomi Shimizu, John Tarlton, Ed Friend, Ivan Doran, Kevin Parsons
OBJECTIVE: To compare the mode of failure, load at yield, ultimate load to failure and stiffness of non-barbed polydioxanone, non-barbed polyglyconate and barbed glycolide-trimethylene carbonate (GTC) suture in canine cadaveric fascia. STUDY DESIGN: Ex vivo biomechanical study. SAMPLE POPULATION: 18 fascia lata specimens from 9 canine cadavers. METHODS: 6 fascia lata specimens were sutured with polydioxanone, 6 with polyglyconate, and 6 with barbed GTC suture...
January 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27904548/the-effect-of-vitamin-d-supplementation-on-gestational-diabetes-in-high-risk-women-results-from-a-randomized-placebo-controlled-trial
#9
Shole Shahgheibi, Fariba Farhadifar, Bahar Pouya
BACKGROUND: Vitamin D deficiency is common in pregnancy, leading to increase in the frequency of preeclampsia, cesarean delivery, neonatal bacterial vaginosis, and gestational diabetes. The current study was designed and implemented to investigate the effect of vitamin D during the first and second trimesters of pregnancy in reducing the risk of gestational diabetes mellitus (GDM) in women who are at high risk [history of GDM, birth macrosomia, family history, and high body mass index (BMI)]...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27683207/genetic-structure-and-diversity-analysis-revealed-by-aflp-markers-on-different-glycyrrhiza-glabra-l-an-endangered-medicinal-species-from-south-of-iran-and-implications-for-conservation
#10
Atieh Hakimi, Maryam Zolfaghari, Karim Sorkheh
Glycyrrhiza glabra is an endangered and national-protected medicinal plant species distributed in semi-arid and arid areas of South of Iran. This study addresses the genetic diversity and relationship between populations in different habitats by amplified fragment length polymorphism (AFLP). The plant materials consisted of 90 individuals from nine different populating areas of Dezful, Ramhormoz, Ahvaz, Abadan, Khorramshahr, Behbahan, Haft-tapeh, Andimeshk, and Shushtar. Twenty-three AFLP primer combinations generated a total of 1019 bands with 94...
September 28, 2016: Biochemical Genetics
https://www.readbyqxmd.com/read/27665735/the-molecular-and-phenotypic-spectrum-of-iqsec2-related-epilepsy
#11
Ayelet Zerem, Kazuhiro Haginoya, Dorit Lev, Lubov Blumkin, Sara Kivity, Ilan Linder, Cheryl Shoubridge, Elizabeth Emma Palmer, Michael Field, Jackie Boyle, David Chitayat, William D Gaillard, Eric H Kossoff, Marjolaine Willems, David Geneviève, Frederic Tran-Mau-Them, Orna Epstein, Eli Heyman, Sarah Dugan, Alice Masurel-Paulet, Ame'lie Piton, Tjitske Kleefstra, Rolph Pfundt, Ryo Sato, Andreas Tzschach, Naomichi Matsumoto, Hirotomo Saitsu, Esther Leshinsky-Silver, Tally Lerman-Sagie
OBJECTIVE: IQSEC2 is an X-linked gene associated with intellectual disability (ID) and epilepsy. Herein we characterize the epilepsy/epileptic encephalopathy of patients with IQSEC2 pathogenic variants. METHODS: Forty-eight patients with IQSEC2 variants were identified worldwide through Medline search. Two patients were recruited from our early onset epileptic encephalopathy cohort and one patient from personal communication. The 18 patients who have epilepsy in addition to ID are the subject of this study...
November 2016: Epilepsia
https://www.readbyqxmd.com/read/27593352/chemical-composition-and-source-apportionment-of-size-fractionated-particulate-matter-in-cleveland-ohio-usa
#12
Yong Ho Kim, Q Todd Krantz, John McGee, Kasey D Kovalcik, Rachelle M Duvall, Robert D Willis, Ali S Kamal, Matthew S Landis, Gary A Norris, M Ian Gilmour
The Cleveland airshed comprises a complex mixture of industrial source emissions that contribute to periods of non-attainment for fine particulate matter (PM2.5) and are associated with increased adverse health outcomes in the exposed population. Specific PM sources responsible for health effects however are not fully understood. Size-fractionated PM (coarse, fine, and ultrafine) samples were collected using a ChemVol sampler at an urban site (G.T. Craig (GTC)) and rural site (Chippewa Lake (CLM)) from July 2009 to June 2010, and then chemically analyzed...
November 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27411798/generalized-convulsion-complicating-acute-diffuse-pulmonary-hemorrhage-the-report-of-a-rare-case
#13
Pei-Ya Chen, Mei-Chen Yang, Yi-Chih Huang, Shinn-Kuang Lin
PURPOSE: The immediate complications associated with a generalized tonic-clonic (GTC) seizure usually involve injuries such as aspiration pneumonia, head injury, skull or vertebral fracture and orolingual biting injury. Here we present a young man who suffered from GTC that was followed by a rare complication, acute diffuse pulmonary hemorrhage, which presented with massive hemoptysis and subsequent respiratory failure. CASE REPORT: An 18-year-old boy developed a GTC convulsion that lasted for about two minutes and then regained consciousness 15 minutes later...
March 2016: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/27354088/vulnerability-of-the-peatland-carbon-sink-to-sea-level-rise
#14
Alex Whittle, Angela V Gallego-Sala
Freshwater peatlands are carbon accumulating ecosystems where primary production exceeds organic matter decomposition rates in the soil, and therefore perform an important sink function in global carbon cycling. Typical peatland plant and microbial communities are adapted to the waterlogged, often acidic and low nutrient conditions that characterise them. Peatlands in coastal locations receive inputs of oceanic base cations that shift conditions from the environmental optimum of these communities altering the carbon balance...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27348780/irf-3-gene-polymorphisms-are-associated-with-the-susceptibility-to-and-the-survival-in-chronic-lymphocytic-leukemia-and-could-also-serve-as-an-auxiliary-index
#15
Zong-Xin Zhang, Cui-Fen Shen, Li-Hong Shou, Qiu Fang
The objective of this article was to investigate the relationship between IRF-3 gene polymorphisms and the susceptibility and prognosis of CLL. Between January 2011 and August 2012, 108 CLL patients and 112 healthy were enrolled in the study. DHPLC and Shesis software were applied in our study. In rs7251, CG genotype may increase the CLL risk. In the rs2304206, the alleles T may increase the CLL risk. The GTC haplotype can decrease the CLL risk in normal people, the GTT haplotype can increase the CLL risk in normal people...
June 27, 2016: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/27347227/ictal-cardiac-ryhthym-abnormalities
#16
Rushna Ali
Cardiac rhythm abnormalities in the context of epilepsy are a well-known phenomenon. However, they are under-recognized and often missed. The pathophysiology of these events is unclear. Bradycardia and asystole are preceded by seizure onset suggesting ictal propagation into the cortex impacting cardiac autonomic function, and the insula and amygdala being possible culprits. Sudden unexpected death in epilepsy (SUDEP) refers to the unanticipated death of a patient with epilepsy not related to status epilepticus, trauma, drowning, or suicide...
2016: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/27311496/validity-and-reliability-of-intraoperative-radiographs-to-assess-leg-length-during-total-hip-arthroplasty-correlation-and-reproducibility-of-anatomic-distances
#17
Olivier Herisson, Arnaud Felden, Moussa Hamadouche, Philippe Anract, David J Biau
BACKGROUND: Leg length discrepancy after total hip arthroplasty is a frequent complication. The aim of this study was to assess the validity (correlation) and reproducibility (inter-rater agreement) of various intraoperative hip radiographs measures to estimate leg length. METHODS: Patients were included if they were aged 15 years or older; were eligible for a total hip arthroplasty, and were operated in lateral recumbent. An intraoperative hip radiograph was performed with the definitive implants in place...
May 11, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27300146/high-dose-versus-low-dose-valproate-for-the-treatment-of-juvenile-myoclonic-epilepsy-going-from-low-to-high
#18
Laura E Hernández-Vanegas, Aurelio Jara-Prado, Adriana Ochoa, Nayelli Rodríguez Y Rodríguez, Reyna M Durón, Daniel Crail-Meléndez, Ma Elisa Alonso, Antonio V Delgado-Escueta, Iris E Martínez-Juárez
Juvenile myoclonic epilepsy (JME) is a genetic generalized epilepsy accounting for 3-12% of adult cases of epilepsy. Valproate has proven to be the first-choice drug in JME for controlling the most common seizure types: myoclonic, absence, and generalized tonic-clonic (GTC). In this retrospective study, we analyzed seizure outcome in patients with JME using valproate monotherapy for a minimum period of one year. Low valproate dose was considered to be 1000mg/day or lower, while serum levels were considered to be low if they were at or below 50mcg/dl...
August 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27196943/identification-of-a-novel-hla-c-03-variant-c-03-303-by-sequence-based-typing-in-a-dai-chinese-individual
#19
P C Su, J Wang, X Ji, H L Ma, Z Liu
HLA-C*03:303 has one nonsynonymous nucleotide change from HLA-C*03:04:01:01 in codon 194, exon 4 (GTC>GCC).
June 2016: HLA
https://www.readbyqxmd.com/read/27196379/use-of-rna-amplification-and-electrophoresis-for-studying-virus-aerosol-collection-efficiency-and-their-comparison-with-plaque-assays
#20
Xiao Jiang, Maohua Pan, Susanne V Hering, John Lednicky, Chang-Yu Wu, Z Hugh Fan
The spread of virus-induced infectious diseases through airborne routes of transmission is a global concern for economic and medical reasons. To study virus transmission, it is essential to have an effective aerosol collector such as the growth tube collector (GTC) system that utilizes water-based condensation for collecting virus-containing aerosols. In this work we characterized the GTC system using bacteriophage MS2 as a surrogate for a small RNA virus. We investigated using RNA extraction and reverse-transcriptase polymerase chain reaction (RT-PCR) to study the total virus collection efficiency of the GTC system...
May 16, 2016: Electrophoresis
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