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https://www.readbyqxmd.com/read/28641366/human-papillomavirus-vaccine-dose-effectiveness-against-incident-genital-warts-in-a-cohort-of-insured-us-females
#1
Susan Hariri, Megan S Schuler, Allison L Naleway, Matthew F Daley, Sheila Weinmann, Bradley Crane, Sophia R Newcomer, Dennis Tolsma, Lauri E Markowitz
We examined effectiveness of HPV vaccination by dose number and interval against incident genital warts in a cohort of 64,517 females in the United States during 8/2006-9/2012. Eligible females were classified into 0, 1-dose, 2-dose < 6 months apart, 2-dose ≥6 months apart, and 3-dose groups and followed until genital wart diagnosis, loss to follow-up, or end of study. Propensity score weights were used to balance baseline differences across groups. To account for latent genital warts before vaccination, 6-month and 12-month buffer periods from last and first vaccine dose, respectively, were applied...
June 21, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28641049/a-study-of-physicians-experiences-with-recommending-hpv-vaccines-to-adolescent-boys
#2
Li Ping Wong, Zobaida Edib, Haridah Alias, Sharina M Mohamad Shakir, Raja N A Raja Muhammad Yusoff, I-Ching Sam, Gregory D Zimet
Assessing physicians' experiences in HPV vaccine recommendation and delivery to adolescent boys is essential to providing an understanding of the issues of vaccine acceptance and an insight for policymakers to enhance HPV vaccinations among adolescent boys. Between January and April 2014 a mail survey was conducted using physicians in Malaysia known to provide either one or both HPV vaccine (Gardasil and Cervarix) immunisation services. A total of 357 completed questionnaires were received (response rate 22...
June 22, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28636869/association-between-sexual-mixing-and-genital-warts-in-heterosexual-men-in-australia-the-herd-protection-from-the-female-human-papillomavirus-vaccination-program
#3
Eric P F Chow, Christopher K Fairley
Australian-born women aged ≤32 years were eligible for the free female human papillomavirus (HPV) vaccination program introduced in 2007. A total of 1165 heterosexual couples attending the Melbourne Sexual Health Centre between 2011 and 2014 were included in this analysis. Findings showed the odds of having penile warts was 0.52-fold lower among men who had a female partner aged ≤32 years compared with men who had a female partners aged >32 years. This suggests men would have received herd protection from their female partners and hence they are at lower risk of acquiring genital warts...
October 2016: Sexual Health
https://www.readbyqxmd.com/read/28633892/seropositivity-to-non-vaccine-incorporated-genotypes-induced-by-the-bivalent-and-quadrivalent-hpv-vaccines-a-systematic-review-and-meta-analysis
#4
Sara L Bissett, Anna Godi, Mark Jit, Simon Beddows
BACKGROUND: Human papillomavirus vaccines have demonstrated remarkable efficacy against persistent infection and disease associated with vaccine-incorporated genotypes and a degree of efficacy against some genetically related, non-vaccine-incorporated genotypes. The vaccines differ in the extent of cross-protection against these non-vaccine genotypes. Data supporting the role for neutralizing antibodies as a correlate or surrogate of cross-protection are lacking, as is a robust assessment of the seroconversion rates against these non-vaccine genotypes...
June 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28632949/potential-impact-of-nonavalent-hpv-vaccine-in-the-prevention-of-high-grade-cervical-lesions-and-cervical-cancer-in-portugal
#5
Angela Pista, Carlos Freire de Oliveira, Carlos Lopes, Maria J Cunha
OBJECTIVE: To estimate the potential impact of the nonavalent HPV vaccine for high-grade cervical lesions and invasive cervical cancer (ICC) in Portugal. METHODS: The present secondary analysis used data collected in the CLEOPATRE II study on the prevalence of HPV 6/11/16/18/31/33/45/52/58 among female patients aged 20-88 years. The prevalence of HPV types in patients with cervical intraepithelial neoplasia (CIN) grades 2/3 and ICC was examined. RESULTS: Data were included from 582 patients...
June 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28629588/human-papillomavirus-and-its-testing-assays-cervical-cancer-screening-and-vaccination
#6
Yusheng Zhu, Yun Wang, Julie Hirschhorn, Kerry J Welsh, Zhen Zhao, Michelle R Davis, Sarah Feldman
Human papillomavirus (HPV) was found to be the causative agent for cervical cancer in the 1980s with almost 100% of cervical cancer cases testing positive for HPV. Since then, many studies have been conducted to elucidate the molecular basis of HPV, the mechanisms of carcinogenesis of the virus, and the risk factors for HPV infection. Traditionally, the Papanicolaou test was the primary screening method for cervical cancer. Because of the discovery and evolving understanding of the role of HPV in cervical dysplasia, HPV testing has been recommended as a new method for cervical cancer screening by major professional organizations including the American Cancer Society, American Society for Colposcopy and Cervical Pathology, and the American Society for Clinical Pathology...
2017: Advances in Clinical Chemistry
https://www.readbyqxmd.com/read/28626810/human-papillomavirus-hpv-in-young-women-in-britain-population-based-evidence-of-the-effectiveness-of-the-bivalent-immunisation-programme-and-burden-of-quadrivalent-and-9-valent-vaccine-types
#7
Clare Tanton, David Mesher, Simon Beddows, Kate Soldan, Soazig Clifton, Kavita Panwar, Nigel Field, Catherine H Mercer, Anne M Johnson, Pam Sonnenberg
BACKGROUND: In 2008, the UK introduced an HPV immunisation programme in girls. Population-based prevalence estimates of bivalent (HPV-16/18), quadrivalent (HPV-6/11/16/18) and 9-valent (HPV-6/11/16/18/31/33/45/52/58) vaccine types, and comparison over time, are needed to monitor impact, evaluate effectiveness and guide decision-making on vaccination strategies. METHODS: The third National Survey of Sexual Attitudes and Lifestyles (Natsal-3) in 2010-12, tested urine for HPV from 2569 sexually-experienced women aged 16-44...
June 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/28622401/impact-of-a-pharmacist-conducted-educational-program-on-human-papilloma-virus-vaccination-rates-in-a-low-socioeconomic-population-in-the-city-of-lares-pr
#8
Edda Marie Jiménez-Quiñones, Kyle Melin, Francisco Javier Jiménez-Ramírez
OBJECTIVE: To observe whether local vaccination rates are improved by a patient and physician education program on the human papillomavirus (HPV) vaccine in Farmacia San José, Lares. According to the Puerto Rico Immunization Registry, the HPV vaccine is currently underutilized. METHODS: Patients within the ages of 18 and 26 years who are current patients of Farmacia San José were contacted by phone and approached in person at the pharmacy. Once contacted, patients were provided with educational materials and counseling regarding the risks and benefits of HPV vaccination...
June 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28620555/a-discussion-of-high-risk-hpv-in-a-6-year-old-female-survivor-of-child-sexual-abuse
#9
Connie D Cao, Lena Merjanian, Joelle Pierre, Adrian Balica
BACKGROUND: Human papilloma viruses (HPVs) cause a variety of clinical manifestations in children including skin warts, laryngeal papillomas, and condyloma acuminatum. Whereas the mode of transmission is well understood and management of HPV infection is clearly defined by guidelines in adults, less is known about the mode of transmission, natural history of disease, and appropriate management of high-risk anogenital HPV infections in children. CASE: The patient is a previously healthy 6-year-old female who presented with multiple vaginal lesions causing pain and discomfort and was diagnosed with HPV 18 positive CIN I...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28614466/prevalence-of-high-risk-human-papillomavirus-among-women-in-two-english-speaking-caribbean-countries
#10
Glennis Andall-Brereton, Eulynis Brown, Sherian Slater, Yvette Holder, Silvana Luciani, Merle Lewis, Beryl Irons
Objective: To characterize high-risk human papillomavirus (HPV) infections in a sample of women in two small English-speaking Caribbean countries: Saint Kitts and Nevis and Saint Vincent and the Grenadines. Methods: Sexually active women ≥ 30 years old attending primary care health facilities participated in the study. Each participant had a gynecological examination, and two cervical specimens were collected: (1) a specimen for a Papanicolaou (Pap) test and (2) a sample of exfoliated cervical cells for HPV DNA testing, using the HPV High Risk Screen Real-TM (Sacace)...
June 8, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28610824/safety-and-perception-what-are-the-greatest-enemies-of-hpv-vaccination-programmes
#11
Paolo Bonanni, Beatrice Zanella, Francesca Santomauro, Chiara Lorini, Angela Bechini, Sara Boccalini
Vaccines stimulate a person's immune system to produce an adequate reaction against a specific infectious agent; i.e. the person is protected from that disease without having to get it first. As vaccines are administrated to healthy subjects, they are held to the highest standards of safety. Regarding human papillomavirus (HPV) vaccines, at present three prophylactic vaccines are licensed (bivalent HPV 16/18, quadrivalent HPV 6/11/16/18 and the nonovalent HPV 6/11/16/18/31/33/45/52/58 vaccine). Pre- and post-licensure studies (i...
June 10, 2017: Vaccine
https://www.readbyqxmd.com/read/28610408/knowledge-and-awareness-about-cervical-cancer-vaccine-hpv-among-parents-in-sharjah
#12
Ahmad Saqer, Shaymaa Ghazal, Hiba Barqawi, Juman Adnan Babi, Ranya AlKhafaji, Mohamed Mohsen Elmekresh
Background and aim: Cervical cancer (CC) is the 7th most common cancer worldwide. It is the 4th most common cancer in females causing 7.5% of all female cancer deaths. Human Papilloma Virus (HPV) infection is the leading cause of CC and other diseases worldwide. Despite several measures taken to reduce the risk of infection with HPV, the most effective method remains the HPV vaccine. The aim of this study was to assess the knowledge and attitudes of parents in Sharjah towards HPV and whether or not they would vaccinate their daughters...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28608796/the-natural-history-of-oral-human-papillomavirus-in-young-costa-rican-women
#13
Daniel C Beachler, Krystle A Lang Kuhs, Linda Struijk, John Schussler, Rolando Herrero, Carolina Porras, Allan Hildesheim, Bernal Cortes, Joshua Sampson, Wim Quint, Paula Gonzalez, Aimée R Kreimer
BACKGROUND: Oral human papillomavirus (HPV) infection and related oropharyngeal cancer are uncommon in lower-income countries, particularly compared to HPV-associated cervical cancer. However, little is known about the natural history of oral HPV in less-developed settings and how it compares to the natural history of cervical HPV. METHODS: Three hundred fifty women aged 22 to 33 years from the Costa Rica Vaccine Trial provided exfoliated cells from the cervical and oral regions at 2 visits 2 years apart...
July 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28608795/human-papillomavirus-vaccination-among-young-men-who-have-sex-with-men-and-transgender-women-in-2-us-cities-2012-2014
#14
Pamina M Gorbach, Ryan Cook, Beau Gratzer, Thomas Collins, Adam Parrish, Janell Moore, Peter R Kerndt, Richard A Crosby, Lauri E Markowitz, Elissa Meites
BACKGROUND: Since 2011, in the United States, quadrivalent human papillomavirus (HPV) vaccine has been recommended for boys aged 11 to 12 years, men through age 21, and men who have sex with men (MSM) through age 26. We assessed HPV vaccination coverage and factors associated with vaccination among young MSM (YMSM) and transgender women (TGW) in 2 cities. METHODS: During 2012-2014, 808 YMSM and TGW aged 18 to 26 years reported vaccination status in a self-administered computerized questionnaire at 3 sexually transmitted disease (STD) clinics in Los Angeles and Chicago...
July 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28607602/cervical-cancers-manifest-a-high-rate-of-infection-by-a-high-risk-human-papilloma-virus-subtype-but-a-very-low-rate-of-infection-by-a-low-risk-subtype-in-the-guiyang-district-of-china
#15
Juan Peng, Yan Yuan, Feng Shen, Yan Wang, Lichan Chen, D Joshua Liao, Yujie Tan
The prevalence of infection by different genotypes of human papillomavirus (HPV) varies among different geographic areas. We studied the prevalence of infection by 21 HPV genotypes in cervical tissue specimens from 4213 women in the Guiyang district, that is located in the southwest of China and is dominated by minor ethnicities of Chinese, and 2074 cases in our cohort had pathological diagnosis available. The overall infection rate was 36.98%. Most (72.08%) infectors were positive for only one HPV subtype, with the remaining being cases infected by two or more subtypes...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28607581/pembrolizumab-in-cervical-cancer-latest-evidence-and-clinical-usefulness
#16
REVIEW
Edith Borcoman, Christophe Le Tourneau
Cervical cancer is the fourth most common cause of cancer-related deaths in women worldwide. With the development of detection of precancerous lesions and preventive human papillomavirus (HPV) vaccination program, a survival improvement has been observed in these patients in developed countries, although disparities in accessibility to treatments exist across countries. While early-stage cervical cancer can be curable with surgery, prognosis of patients who recur remains poor, with limited treatment options...
June 2017: Therapeutic Advances in Medical Oncology
https://www.readbyqxmd.com/read/28605256/adolescent-human-papillomavirus-vaccination-in-the-united-states-opportunities-for-integrating-pharmacies-into-the-immunization-neighborhood
#17
Joseph P Fava, Jacob Colleran, Francesca Bignasci, Raymond Cha, Paul E Kilgore
Human Papillomavirus (HPV) vaccination faces several barriers, including a social stigma which carries religious and philosophical implications among parents of adolescents as well as young adults. Hundreds of immunization interventions and programs have been developed to address these factors and boost HPV vaccination rates in the United States. We sought to review the existing literature highlighting barriers to HPV immunization, as well as programs targeting increased HPV vaccine uptake in effort to develop novel vaccination initiatives...
June 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28604441/increasing-human-papillomavirus-vaccine-coverage-among-men-who-have-sex-with-men-national-hiv-behavioral-surveillance-united-states-2014
#18
Sara E Oliver, Brooke E Hoots, Gabriela Paz-Bailey, Lauri E Markowitz, Elissa Meites
BACKGROUND: Human papillomavirus (HPV) can cause oropharyngeal and anogenital cancers among men who have sex with men (MSM). In 2011, the Advisory Committee on Immunization Practices (ACIP) extended HPV vaccine recommendations to males through age 21 and MSM through age 26. Because of this distinction, vaccination for some MSM might rely on sexual behavior disclosure to health care providers. Receipt of ≥1 HPV vaccination among MSM aged 18-26 in National HIV Behavioral Surveillance (NHBS) was 4...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604258/relationship-between-maternal-experiences-and-adolescent-hpv-vaccination
#19
Abbey B Berenson, V Gnaukita Brown, Erika L Fuchs, Jacqueline M Hirth, Mihyun Chang
The human papillomavirus (HPV) vaccine has been available for over a decade but its uptake rate is still low. To explore the relationship between the HPV vaccination status of a child and their mother's beliefs, behaviors and knowledge, we surveyed 1497 women with at least one child aged 9-17 years between September 2011 and November 2015. Physician recommendation was the most important factor associated with reported child vaccination status. Mothers who reported receiving a provider recommendation for the HPV vaccine were 32 times more likely to have a child who had been vaccinated compared to mothers who did not report provider recommendation (aOR) = 32...
June 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28604161/history-repeats-itself-in-japan-failure-to-learn-from-rubella-epidemic-leads-to-failure-to-provide-the-hpv-vaccine
#20
Yusuke Tanaka, Yutaka Ueda, Kiyoshi Yoshino, Tadashi Kimura
Eradication of vaccine-preventable diseases is one of the most important goals of public health interventions. Herd immunity can be established by national vaccination programs. However, once the national vaccination program stops for any reason, unprotected group will be generated depending on an unfortunate year of birth. Currently, there are 2 major concerns regarding vaccine cohort gaps in Japan: one is for the rubella vaccine, the other for the human papillomavirus (HPV) vaccine.
June 12, 2017: Human Vaccines & Immunotherapeutics
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