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Hpv vaccine

M Butsashvili, M Kajaia, M Kochlamazashvili, M Zarandia, T Gagua, D Meskhishvili, N Avaliani, G Kamkamidze
Of the 100 types of human papillomaviruses (HPV), approximately 35 infect the genital tract. The viruses are categorized as "high risk" and "low risk" depending on whether they are known to cause cancer or not. Cervical cancer is an important cause of cancer mortality in Georgia, and worldwide. Only limited and incomplete data are available about the epidemiology of HPV infection and related molecular and cellular changes in Georgia. Objectives of our study included the estimation of the prevalence and the distribution of HPV genotypes among women in Georgia...
September 2016: Georgian Medical News
Sonia Menon, Aibibula Wusiman, Marie Claude Boily, Mbabazi Kariisa, Hillary Mabeya, Stanley Luchters, Frode Forland, Rodolfo Rossi, Steven Callens, Davy Vanden Broeck
BACKGROUND: There is a scarcity of data on the distribution of human papillomavirus (HPV) genotypes in the HIV positive population and in invasive cervical cancer (ICC) in Kenya. This may be different from genotypes found in abnormal cytology. Yet, with the advent of preventive HPV vaccines that target HPV 16 and 18, and the nonavalent vaccine targeting 90% of all ICC cases, such HPV genotype distribution data are indispensable for predicting the impact of vaccination and HPV screening on prevention...
2016: PloS One
Anagha Loharikar, Laure Dumolard, Susan Chu, Terri Hyde, Tracey Goodman, Carsten Mantel
Since the global Expanded Program on Immunization (EPI) was launched in 1974, vaccination against six diseases (tuberculosis, polio, diphtheria, tetanus, pertussis, and measles) has prevented millions of deaths and disabilities (1). Significant advances have been made in the development and introduction of vaccines, and licensed vaccines are now available to prevent 25 diseases (2,3). Historically, new vaccines only became available in low-income and middle-income countries decades after being introduced in high-income countries...
October 21, 2016: MMWR. Morbidity and Mortality Weekly Report
Melissa B Gilkey, William A Calo, Macary W Marciniak, Noel T Brewer
BACKGROUND: We sought to estimate the national prevalence of HPV vaccine refusal and delay in a population-based sample of parents of adolescents. We also compared parents who refused versus delayed HPV vaccine in terms of their vaccination beliefs and clinical communication preferences. METHODS: In 2014 to 2015, we conducted an online survey of 1,484 U.S. parents who reported on an 11- to 17-year-old child in their household. We used weighted multinomial logistic regression to assess correlates of HPV vaccine refusal and delay...
October 20, 2016: Human Vaccines & Immunotherapeutics
Pande Kadek Aditya Prayudi, Anak Agung Istri Yulan Permatasari, I Gde Sastra Winata, Ketut Suwiyoga
AIM: To determine the impact of human papilloma virus (HPV) vaccination on knowledge, perception of sexual risk and need for continued safe sexual behavior among Indonesian girls. METHODS: A comparative cross-sectional study was carried on in Denpasar, the capital city of Bali, Indonesia, during September 2015-February 2016. A total of 828 adolescent girls (12-16 years) were recruited to assess their knowledge on HPV/HPV vaccine, perception of sexual risks and need for continued safe sexual behavior...
October 20, 2016: Journal of Obstetrics and Gynaecology Research
T M Kolben, C Dannecker, K Baltateanu, C Goess, T Starrach, A Semmlinger, N Ditsch, J Gallwas, S Mahner, K Friese, T Kolben
Purpose: In order to achieve a higher vaccination rate, education on HPV as well as options for prophylaxis performed by doctors is of great importance. One opportunity to increase the protection against HPV would be vaccinating boys. This study evaluated attitude and knowledge among German gynecologists regarding HPV vaccination, especially in boys. Material and Methods: A questionnaire with 42 questions about demographics, attitude and knowledge about HPV and HPV vaccination was sent to members of the German Society for Gynecology and Obstetrics (DGGG)...
October 2016: Geburtshilfe und Frauenheilkunde
M G Grunberg, M Chan, M R Adhin
Suriname is ranked as high-risk country for cervical cancer, but recent national data of HPV prevalence and distribution in cervical cancer is scarce. In a retrospective cross-sectional study, cervical cancer incidence, HPV prevalence and HPV-type-specific distribution were investigated in all cervical cancer cases (n = 111), diagnosed in two consecutive years. HPV presence and type-specific prevalence were determined in paraffin-embedded biopsies utilizing master-nested multiplex PCR assays, targeting 14 HPV types...
October 20, 2016: Epidemiology and Infection
Sarah Igidbashian, Sara Boveri, Fabio Bottari, Ailyn Vidal Urbinati, Eleonora Preti, Chiara Casadio, Fabio Landoni, Mario Sideri, Maria Teresa Sandri
OBJECTIVES: Little is known about the epidemiology of human papillomavirus (HPV) in Italy before the age of 25. At the European Institute of Oncology, a prospective observational study on cervical HPV infection in 18-year-old women undergoing quadrivalent HPV vaccination is ongoing. METHODS: At the first visit before vaccination, all the young women answered an epidemiological questionnaire, and then, the presence of high-risk HPV (hrHPV) was tested. Samples positive for hrHPV were genotyped...
October 17, 2016: Journal of Lower Genital Tract Disease
Jane J Kim, Emily A Burger, Stephen Sy, Nicole G Campos
BACKGROUND: Current US cervical cancer screening guidelines do not differentiate recommendations based on a woman's human papillomavirus (HPV) vaccination status. Changes to cervical cancer screening policies in HPV-vaccinated women should be evaluated. METHODS: We utilized an individual-based mathematical model of HPV and cervical cancer in US women to project the health benefits, costs, and harms associated with screening strategies in women vaccinated with the bivalent, quadrivalent, or nonavalent vaccine...
February 2017: Journal of the National Cancer Institute
Dana Whittemore, Lili Ding, Lea E Widdice, Darron A Brown, David I Bernstein, Eduardo L Franco, Jessica A Kahn
BACKGROUND: Previous studies have demonstrated racial and ethnic differences in the distribution of human papillomavirus (HPV) types among adult women with cervical precancers. The aim of this study was to determine whether the distribution of vaccine-targeted HPV types varies by race/ethnicity among unvaccinated young women. MATERIALS AND METHODS: A secondary analysis was performed using data from four studies of sexually experienced, unvaccinated, 13-26-year-old women...
October 18, 2016: Journal of Women's Health
Philip M Massey, Ruth K Boansi, Jessica D Gipson, Rachel M Adams, Helene Riess, Thierno Dieng, Michael L Prelip, Deborah C Glik
OBJECTIVE: To examine HPV vaccine awareness and receptivity among adolescents and young adults in Senegal. METHODS: Participants from 6 high schools and 5 community centers across five regions of Senegal (n=2,286) completed a self-administered questionnaire in October and November 2014. The study assessed HPV awareness and receptivity toward receiving the HPV vaccine. Multivariable logistic regression explored statistically significant relationships between the predictor variables and both outcomes...
October 18, 2016: Tropical Medicine & International Health: TM & IH
Sarah Wedel, Rebecca Navarrete, Joseph F Burkard, Mary Jo Clark
The purpose of this evidence-based project was to provide patient education to increase human papillomavirus (HPV) vaccination rates in military women. Despite the availability of a vaccine, HPV continues to be the most common sexually transmitted infection in the United States. The goal of this program was to increase patient knowledge and HPV vaccination rates by providing education and a verbal recommendation for vaccination during regularly scheduled well-woman exams. The project resulted in a 65% increase in vaccination rates, raising the preprogram vaccination rate of 55% to a postintervention vaccine percentage of 91%...
October 2016: Military Medicine
Carmen Radecki Breitkopf, Lila J Finney Rutten, Victoria Findley, Debra J Jacobson, Patrick M Wilson, Monica Albertie, Robert M Jacobson, Gerardo Colón-Otero
Human papillomavirus (HPV) vaccines offer primary prevention of cervical cancer and protection against other HPV-associated cancers. HPV vaccine coverage in the United States (U.S.) remains low, particularly among older adolescents/young adults, and the uninsured. We assessed awareness and knowledge of HPV disease, HPV-related cancers, and HPV vaccines among working, uninsured adults. Data from the 2014 Health Information National Trends Survey (HINTS 4, Cycle 4) were used as a benchmark. Patients were surveyed in late 2014 at the Volunteers in Medicine free clinic in Duval County, Florida...
October 17, 2016: Cancer Medicine
Nobuyoshi Ozawa, Kiyoshi Ito, Toru Tase, Hirohito Metoki, Nobuo Yaegashi
Prevention of cervical cancer has been unsuccessful in Japan because of low rates of cancer screening and vaccination. The Vaccine Adverse Review Committee of the Japanese Government investigated 2,475 adverse events and reported 617 (6.9/100,000) severe cases and 176 (2.0/100,000) cases with chronic pain. The proactive recommendation for human papillomavirus (HPV) vaccination has been suspended since June 2013. In this study, we examined vaccination rate and incidence of abnormal cervical cytology in women aged 20 to 24 years attending cancer screening in Miyagi...
2016: Tohoku Journal of Experimental Medicine
J L Yoost, R W Starcher, R A King-Mallory, N Hussain, C A Hensley, T W Gress
STUDY OBJECTIVE: To evaluate the use of telehealth to teach reproductive health to rural areas with high rates of teen pregnancy. DESIGN: Prospective cohort study SETTING: Two high schools in rural West Virginia. PARTICIPANTS: High school females that attended telehealth sessions. INTERVENTIONS: Teleconferencing equipment connected rural high schools to a distal academic institution. Telehealth sessions included reproductive health and life skills topics...
October 11, 2016: Journal of Pediatric and Adolescent Gynecology
Nicolas F Schlecht, Angela Diaz, Viswanathan Shankar, Arnold H Szporn, Maoxin Wu, Anne Nucci-Sack, Ken Peake, Howard D Strickler, Robert D Burk
BACKGROUND:  Uptake of the human papillomavirus (HPV) vaccine in the United States is slow, and the real-world effectiveness of the vaccine has not been assessed in high-risk adolescent populations. METHODS:  We conducted a longitudinal study of 1139 sexually-active, inner-city adolescent women receiving the 3-dose quadrivalent (4vHPV) vaccine. Cervical and anal specimens collected semi-annually were tested using a L1-PCR assay. Post-vaccination incidence of 4vHPV vaccine and non-vaccine HPV types, and risk of cervical cytological abnormalities, were assessed in relation to time-to-completion of all three vaccine doses...
October 12, 2016: Journal of Infectious Diseases
Joël Ladner, Marie-Hélène Besson, Etienne Audureau, Mariana Rodrigues, Joseph Saba
BACKGROUND: Cervical cancer is the greatest cause of age-weighted years of life lost in the developing world. Human papillomavirus (HPV) infection is associated with a high proportion of cervical cancers, and HPV vaccination may help to reduce the incidence of cancer. The aim of the study was to identify barriers, obstacles, and strategies and to analyze key concerns and lessons learned with respect to the implementation of HPV vaccination program in low- and middle-income countries. METHODS: The Gardasil Access Program (GAP) is a donation program established to enable organizations and institutions in eligible low-resource countries to gain operational experience designing and implementing HPV vaccination programs...
October 13, 2016: BMC Health Services Research
P Morbini, M Benazzo
Human papillomavirus (HPV)-associated squamous cell carcinoma of the oropharynx is a well-defined entity mostly affecting young to middle-aged male non-smokers. It is generally associated with a favourable outcome, and for this reason a less intensive therapeutic approach has been proposed for this subset of patients. The incidence of HPV-associated oropharyngeal cancers is rapidly increasing in most Western countries, but detailed epidemiological data are not available for the Italian population. Furthermore, among other head and neck regions, a smaller proportion of oral high-grade dysplasia and cancers seems to depend on HPV infection, whereas its role in laryngeal cancer is recognised as less relevant...
August 2016: Acta Otorhinolaryngologica Italica
Djin Lai, Julia Bodson, France A Davis, Doriena Lee, Fahina Tavake-Pasi, Edwin Napia, Jeannette Villalta, Valentine Mukundente, Ryan Mooney, Heather Coulter, Louisa A Stark, Ana C Sanchez-Birkhead, Deanna Kepka
Current sources of publicly available human papillomavirus (HPV) information may not adequately meet the needs of diverse families. This study sought to describe associations between sociodemographic and acculturation factors, and sources of HPV information among diverse parents and caregivers. Community organizations purposively recruited participants from African American, African refugee, Hispanic/Latino, American Indian, and Native Hawaiian and Pacific Islander communities for a 21-item survey (N = 228)...
October 12, 2016: Journal of Community Health
Devinder M Thappa, Minu J Chiramel
Cutaneous and genital warts are common dermatological conditions caused by the human papilloma virus (HPV). Although it is a benign condition, it causes disfigurement, has a tendency to koebnerize, and can be transmitted to others. This makes adequate and timely treatment important. There are several conventional treatments available with variable response. Topical and systemic immunotherapy has now found a significant place in the treatment of warts because of its nondestructive action, ease of use, and promising results...
September 2016: Indian Dermatology Online Journal
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