Vanessa Menezes, Clare Pollock, Pasquale Ferraro, Basil Nasir, Charles Leduc, Julie Morisset, Moishe Liberman
BACKGROUND: To evaluate optimal settings of probe size, freezing time, and distance to the pleura that influence the size and quality of biopsy specimens during transbronchial lung cryobiopsies in ESPD. METHODS: We prospectively recruited 17 patients undergoing lung transplantation. We created a nonperfused ex vivo bronchoscopy setting to perform multiple cryobiopsies with different probe sizes (1.7, 1.9, and 2.4 mm), freezing times (3, 5, 7, 10, 20, 30 seconds), and probe distance from pleura (5, 10, and 20 mm)...
October 9, 2023: Journal of Bronchology & Interventional Pulmonology