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anticoagulation and regional anesthesia

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https://www.readbyqxmd.com/read/27900415/-management-of-anesthesia-in-endovascular-interventions
#1
T Rössel, R Paul, T Richter, S Ludwig, T Hofmockel, A R Heller, T Koch
Cardiovascular diseases are one of the leading causes of morbidity and mortality in Germany. In these patients, the high-risk profile necessitates an interdisciplinary and multimodal approach to treatment. Endovascular interventions and vascular surgery have become established as an important element of this strategy in the past; however, the different anatomical localizations of pathological vascular alterations make it necessary to use a wide spectrum of procedural options and methods; therefore, the requirements for management of anesthesia are variable and necessitate a differentiated approach...
November 29, 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27687455/risk-stratification-perioperative-and-periprocedural-management-of-the-patient-receiving-anticoagulant-therapy
#2
REVIEW
Adriana D Oprea, Christopher J Noto, Thomas M Halaszynski
As a result of the aging US population and the subsequent increase in the prevalence of coronary disease and atrial fibrillation, therapeutic use of anticoagulants has increased. Perioperative and periprocedural management of anticoagulated patients has become routine for anesthesiologists, who frequently mediate communication between the prescribing physician and the surgeon and assess the risks of both thromboembolic complications and hemorrhage. Data from randomized clinical trials on perioperative management of antithrombotic therapy are lacking...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27536909/paraplegia-after-thoracic-epidural-steroid-injection
#3
Vivek Loomba, Hirsh Kaveeshvar, Samvid Dwivedi
Epidural steroid injections are a common procedure performed by pain physicians. The American Society of Regional Anesthesia along with several other groups recently provided guidelines for performing epidural injections in the setting of anticoagulants. We present a case of a patient who developed an epidural hematoma and subsequent paraplegia despite strict adherence to these guidelines. Although new guidelines serve to direct practice, risks of devastating neurologic complications remain as evidenced by our case...
September 1, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27290980/use-of-direct-oral-anticoagulants-with-regional-anesthesia-in-orthopedic-patients
#4
REVIEW
Gianluca Cappelleri, Andrea Fanelli
The use of direct oral anticoagulants including apixaban, rivaroxaban, and dabigatran, which are approved for several therapeutic indications, can simplify perioperative and postoperative management of anticoagulation. Utilization of regional neuraxial anesthesia in patients receiving anticoagulants carries a relatively small risk of hematoma, the serious complications of which must be acknowledged. Given the extensive use of regional anesthesia in surgery and the increasing number of patients receiving direct oral anticoagulants, it is crucial to understand the current clinical data on the risk of hemorrhagic complications in this setting, particularly for anesthesiologists...
August 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27076369/initial-experience-of-the-american-society-of-regional-anesthesia-and-pain-medicine-coags-regional-smartphone-application-a-novel-report-of-global-distribution-and-clinical-usage-of-an-electronic-decision-support-tool-to-enhance-guideline-use
#5
Rajnish K Gupta, Matthew D McEvoy
BACKGROUND AND OBJECTIVES: Decision support tools have been demonstrated to improve adherence to medical guidelines; however, smartphone applications (apps) have not been studied in this regard. In a collaboration between Vanderbilt University and the American Society of Regional Anesthesia and Pain Medicine (ASRA), the ASRA Coags Regional app was created to be a decision support tool for the 2010 published guideline on regional anesthesia for patients receiving anticoagulation. This is a review of the distribution and usage of this app...
May 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/26995947/-placenta-percreta-a-severe-obstetric-complication-despite-correct-diagnosis-a-case-report
#6
Karolina Gruca-Stryjak, Mariola Ropacka-Lesiak, Grzegorz Breborowicz
This paper presents a case of a pregnant woman with a history of two cesarean sections. The patient was admitted to the hospital because of vaginal bleeding. The ultrasound revealed a placenta covering the internal os. The placenta was characterized by heterogeneous echogenicity with visible irregular hypoechogenic areas and blurred border between the placenta and the cervix. Rich vascularity was observed on the border of the placenta, urethra and the urinary bladder. Cystoscopy showed severe congestion around the urethra...
December 2015: Ginekologia Polska
https://www.readbyqxmd.com/read/26952228/effectiveness-of-combined-regional-general-anesthesia-for-reducing-mortality-in-coronary-artery-bypass-meta-analysis
#7
Fabiano Timbó Barbosa, Rafael Martins da Cunha, Fernando Wagner da Silva Ramos, Fernando José Camello de Lima, Amanda Karine Barros Rodrigues, Ailton Mota do Nascimento Galvão, Célio Fernando de Sousa-Rodrigues, Paula Monique Barbosa Lima
BACKGROUND AND OBJECTIVES: Neuraxial anesthesia (NA) has been used in association with general anesthesia (GA) for coronary artery bypass; however, anticoagulation during surgery makes us question the viability of benefits by the risk of epidural hematoma. The aim of this study was to perform a meta-analyzes examining the efficacy of NA associated with GA compared to GA alone for coronary artery bypass on mortality reduction. METHODS: Mortality, arrhythmias, cerebrovascular accident (CVA), myocardial infarction (MI), length of hospital stay (LHS), length of ICU stay (ICUS), reoperations, blood transfusion (BT), quality of life, satisfaction degree, and postoperative cognitive dysfunction were analyzed...
March 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/26882272/periprocedural-management-of-direct-oral-anticoagulants-comment-on-the-2015-american-society-of-regional-anesthesia-and-pain-medicine-guidelines
#8
James D Douketis, Summer Syed, Sam Schulman
No abstract text is available yet for this article.
March 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/26800356/risk-of-hemorrhage-during-needle-based-ophthalmic-regional-anesthesia-in-patients-taking-antithrombotics-a-systematic-review
#9
REVIEW
Augusto Takaschima, Patricia Marchioro, Thiago M Sakae, André L Porporatti, Luis André Mezzomo, Graziela De Luca Canto
BACKGROUND: Patients undergoing ophthalmic surgery are usually elderly and, due to systemic disease, may be on long-term therapy, such as antithrombotic agents. Rates of hemorrhagic complications associated with invasive procedures may be increased by the use of anticoagulants and antiplatelet agents. OBJECTIVE: To compare the incidence of hemorrhagic complications in patients undergoing needle-based ophthalmic regional anesthesia between patients on antithrombotic therapy and those not on such therapy...
2016: PloS One
https://www.readbyqxmd.com/read/26553953/the-effect-of-anesthesia-type-on-major-lower-extremity-amputation-in-functionally-impaired-elderly-patients
#10
COMPARATIVE STUDY
Carla C Moreira, Alik Farber, Jeffrey A Kalish, Mohammad H Eslami, Sebastian Didato, Denis Rybin, Ghoerghe Doros, Jeffrey J Siracuse
OBJECTIVE: Patients undergoing major lower extremity amputations are at risk for a wide variety of perioperative complications. Elderly patients with any functional impairment have been shown to be at high risk for these adverse events. Our goal was to determine the association between the type of anesthesia-general anesthesia (GA) and regional/spinal anesthesia (RA)-on perioperative outcomes after lower extremity amputation in these elderly and functionally impaired patients. METHODS: The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) data set (2005-2012) was queried to identify all patients aged ≥75 years with partial or total functional impairment who underwent major lower extremity amputations...
March 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/26347411/neuraxial-and-peripheral-nerve-blocks-in-patients-taking-anticoagulant-or-thromboprophylactic-drugs-challenges-and-solutions
#11
REVIEW
Jinlei Li, Thomas Halaszynski
Incidence of hemorrhagic complications from neuraxial blockade is unknown, but classically cited as 1 in 150,000 epidurals and 1 in 220,000 spinals. However, recent literature and epidemiologic data suggest that for certain patient populations the frequency is higher (1 in 3,000). Due to safety concerns of bleeding risk, guidelines and recommendations have been designed to reduce patient morbidity/mortality during regional anesthesia. Data from evidence-based reviews, clinical series and case reports, collaborative experience of experts, and pharmacology used in developing consensus statements are unable to address all patient comorbidities and are not able to guarantee specific outcomes...
2015: Local and Regional Anesthesia
https://www.readbyqxmd.com/read/26237236/new-oral-anticoagulants-and-neuraxial-regional-anesthesia
#12
REVIEW
Thomas Volk, Christine Kubulus
PURPOSE OF REVIEW: As the increased use of new oral anticoagulants may put patients at particular risk of bleeding, experts suggested strategies to perform neuraxial anesthesia as well tolerated as possible. This review summarizes different approaches. RECENT FINDINGS: Data from licensing studies, drug pharmacology, registries, authorities and expert opinions are available and covered by the article. Spinal epidural hematoma formation associated with neuraxial blocks is rare...
October 2015: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/26141693/examination-of-regional-anesthesia-for-carotid-endarterectomy
#13
Laura Pasin, Pasquale Nardelli, Giovanni Landoni, Guglielmo Cornero, Silvio Magrin, Yamume Tshomba, Roberto Chiesa, Alberto Zangrillo
OBJECTIVE: Carotid endarterectomy is the most effective treatment for reducing the risk of stroke in patients with significant carotid stenosis. Few studies have focused on the failure rate of regional anesthesia. METHODS: Data of all patients undergoing carotid endarterectomy (June 2009 to December 2014) in a single center were collected. Combined deep and superficial cervical plexus block or superficial plexus block alone was used according to the attending anesthesiologist's choice and the patient's characteristics (eg, dual antiplatelet or anticoagulation therapy)...
September 2015: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/26135797/purple-glove-syndrome-after-phenytoin-or-fosphenytoin-administration-review-of-reported-cases-and-recommendations-for-prevention
#14
REVIEW
Lyudmila A Garbovsky, Byron C Drumheller, Jeanmarie Perrone
The aim of our study was to identify all previously reported cases of phenytoin- or fosphenytoin-associated purple glove syndrome (PGS) and summarize the most current understanding of the pathophysiology, clinical presentation, diagnosis, and treatment of the disease. We searched the English language references from MEDLINE, EMBASE, CINAHL, TOXNET, and gray literature that featured one or more case descriptions of phenytoin- or fosphenytoin-associated PGS after administration and provided information on the clinical setting of the event and associated outcome(s)...
December 2015: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/26027226/-anaesthesia-and-intensive-care-during-intraoperative-intraperitoneal-hyperthermic-chemotherapy-in-patients-with-gastric-cancer-literature-review-and-own-clinical-experience
#15
REVIEW
V E Khoronenko, M M Shemetova, O V Drozhzhina, V M Khomyakov, D D Sobolev
UNLABELLED: Despite a steady decline in the incidence in recent decades, gastric cancer remains one of the most frequent causes of death from cancer in the world. By the time of diagnosis the tumor process is locally advanced or generalized in nearly 70% of patients that reduces the possibility of radical surgical treatment. Peritoneal carcinomatosis is a one of the main causes of treatment failure. There patients need complex treatment with cytoreductive surgery and intraoperative hyperthermic intraperitoneal chemotherapy (IHIC) to improve the quality and duration of life...
January 2015: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/25746164/-effectiveness-of-combined-regional-general-anesthesia-for-reducing-mortality-in-coronary-artery-bypass-meta-analysis
#16
Fabiano Timbó Barbosa, Rafael Martins da Cunha, Fernando Wagner da Silva Ramos, Fernando José Camello de Lima, Amanda Karine Barros Rodrigues, Ailton Mota do Nascimento Galvão, Célio Fernando de Sousa-Rodrigues, Paula Monique Barbosa Lima
BACKGROUND AND OBJECTIVES: Neuraxial anesthesia (NA) has been used in association with general anesthesia (GA) for coronary artery bypass; however, anticoagulation during surgery makes us question the viability of benefits by the risk of epidural hematoma. The aim of this study was to perform a meta-analyzes examining the efficacy of NA associated with GA compared to GA alone for coronary artery bypass on mortality reduction. METHODS: Mortality, arrhythmias, cerebrovascular accident (CVA), myocardial infarction (MI), length of hospital stay (LHS), length of ICU stay (ICUS), reoperations, blood transfusion (BT), quality of life, satisfaction degree, and postoperative cognitive dysfunction were analyzed...
March 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/25731059/-anesthetic-management-of-a-patient-with-trousseau-s-syndrome-and-ovarian-cancer-who-underwent-gynecological-surgery
#17
Mayu Saho, Asuka Ito, Teruyuki Hiraki, Kazuo Ushijima
Trousseau's syndrome, a complex paraneoplastic disease, is characterized by the occurrence of thromboembolic disorders such as brain infarctions in patients with malignant neoplasms. We report the case of a 46-year-old woman with ovarian cancer who had suffered cerebral infarctions and presented with left hemiplegia, aphasia, and atypical genital bleeding. She suffered multiple right brain infarctions, a pulmonary embolism, a right renal infarction with bilateral hydronephrosis and deep venous thromboses and exhibited increased D-dimer and fibrinogen levels and so was administered heparin (10,000 U x day(-1))...
November 2014: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/25199326/-anesthetic-management-of-cesarean-section-in-a-patient-with-pulmonary-embolism-due-to-protein-s-deficiency
#18
Takashi Etoh
A 37-year-old pregnant woman (23 weeks' gestation) was consulted to us because of the left leg pain. On examination, she was diagnosed as deep vein thrombosis (DVT) and pulmonary embolism due to protein S deficiency. She was admitted to our hospital and underwent anticoagulant therapy (heparin 10,000 units per day). At 38 weeks' gestation, she was scheduled for cesarean section. Before operation, she received anticoagulant therapy with continuous infusion of heparin (30,000 units per day) and prophylactic placement of an inferior vena cava (IVC) filter...
August 2014: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/25056411/-risk-consideration-for-peridural-catheter-removal-in-acute-coronary-syndrome-epidural-hematoma-versus-stent-thrombosis
#19
H Böhle, J Fröhlich, R Laufenberg-Feldmann
Perioperative pain therapy using an epidural catheter is the standard operating procedure for numerous surgical interventions. The necessity of initiating anticoagulant therapy in a patient with an epidural catheter requires a careful weighing up between thromboembolic complications and epidural hematoma. The case presented here of a 47-year-old female patient who was operated on for mastectomy with a latissimus dorsi myocutaneous flap demonstrates a possible solution to this dilemma. The patient sustained a perioperative ST elevation myocardial infarction treated with drug-eluting stents while undergoing epidural pain therapy...
September 2014: Der Anaesthesist
https://www.readbyqxmd.com/read/24979070/-new-direct-oral-anticoagulants-in-the-perioperative-setting
#20
REVIEW
Georg Breuer, Dominik R Weiss, Juergen Ringwald
PURPOSE OF REVIEW: Out of the anesthetist's perspective, some uncertainties remain with the perioperative management of the so-called NOACs. This review emphasizes on the question of bleeding and thromboembolic risk as well as the management of bleedings and the discontinuing intervals in the context of regional anesthesia. RECENT FINDINGS: Managing patients with NOAC therapy, an interdisciplinary approach and consent with surgeons and specialist in hemostaseology has to be found...
August 2014: Current Opinion in Anaesthesiology
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