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https://www.readbyqxmd.com/read/28219959/randomised-prospective-medico-economic-nationwide-french-study-of-islet-transplantation-in-patients-with-severely-unstable-type-1-diabetes-the-stabilot-study-protocol
#1
Sandrine Lablanche, Sandra David-Tchouda, Jennifer Margier, Edith Schir, Anne Wojtusciszyn, Sophie Borot, Laurence Kessler, Emmanuel Morelon, Charles Thivolet, François Pattou, Marie Christine Vantyghem, Thierry Berney, Pierre-Yves Benhamou
INTRODUCTION: Islet transplantation may be an appropriate treatment option for patients with severely unstable type 1 diabetes experiencing major glucose variability with severe hypoglycaemia despite intensive insulin therapy. Few data are available on the costs associated with islet transplantation in relation to its benefits. The STABILOT study proposes to assess the economic impact of islet transplantation in comparison with the current best medical treatment defined as sensor-augmented pump (SAP) therapy...
February 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28212900/basic-educational-needs-of-midwifery-students-for-taking-the-role-of-an-assistance-in-disaster-situations-a-cross-sectional-study-in-iran
#2
Z Taghizadeh, M Khoshnam Rad, A Montazeri
BACKGROUND: After disasters, the disaster medical assistance team composed of skilful healthcare staff should be available at the disaster site for providing care to disaster's victims. It is believed that midwives are at the front line of the disaster management team and should be prepared for providing care to mothers and children. OBJECTIVES: To investigate the midwifery students' basic educational needs for taking the role of an assistant in disaster situations...
January 22, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28210554/preoperative-psychosocial-characteristics-may-predict-body-image-and-sexuality-two-years-after-risk-reducing-mastectomy-a-prospective-study
#3
Dmytro Unukovych, Hemming Johansson, Yvonne Brandberg
BACKGROUND: Risk-reducing mastectomy (RRM) in patients at high risk has become more available and the rates of both bilateral (BRRM) and contralateral (CRRM) procedures are increasing. For women opting for RRM, psychosocial well-being, body image and sexuality are known to be important patient-reported outcomes. The aim of the present study was to investigate baseline health-related quality of life (HRQoL) and emotional distress (anxiety and depression) as predictors of body image and sexuality two years after RRM in women undergoing CRRM and BRRM...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28207982/understanding-ethical-issues-of-research-participation-from-the-perspective-of-participating-children-and-adolescents-a-systematic-review
#4
Stacey Crane, Marion E Broome
BACKGROUND: The past 20 years have seen distinct shifts in the way the participation of children and adolescents in research is viewed. This has been emphasized by the growing pediatric research enterprise. Additional information on children's and adolescents' experiences during research participation is needed to better inform researchers on the ethical conduct of research with this vulnerable population. AIMS: The objective of this analysis was to examine ethical issues in research with children and adolescents from their perspective as participants, including: assent, parental consent, risk perception, impact of research participation, and incentives...
February 16, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28207285/improvements-in-clinical-trials-information-will-improve-the-reproductive-health-and-fertility-of-cancer-patients
#5
Angela Dauti, Brigitte Gerstl, Serena Chong, Orin Chisholm, Antoinette Anazodo
There are a number of barriers that result in cancer patients not being referred for oncofertility care, which include knowledge about reproductive risks of antineoplastic agents. Without this information, clinicians do not always make recommendations for oncofertility care. The objective of this study was to describe the level of reproductive information and recommendations that clinicians have available in clinical trial protocols regarding oncofertility management and follow-up, and the information that patients may receive in clinical trials patient information sheets or consent forms...
February 16, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28203065/oral-drug-therapy-in-elderly-with-dysphagia-between-a-rock-and-a-hard-place
#6
REVIEW
Serena Logrippo, Giovanna Ricci, Matteo Sestili, Marco Cespi, Letizia Ferrara, Giovanni F Palmieri, Roberta Ganzetti, Giulia Bonacucina, Paolo Blasi
Demographic indicators forecast that by 2050, the elderly will account for about one-third of the global population. Geriatric patients require a large number of medicines, and in most cases, these products are administered as solid oral solid dosage forms, as they are by far the most common formulations on the market. However, this population tends to suffer difficulties with swallowing. Caregivers in hospital geriatric units routinely compound in solid oral dosage forms for dysphagic patients by crushing the tablets or opening the capsules to facilitate administration...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28202500/canwalk-a-feasibility-study-with-embedded-randomised-controlled-trial-pilot-of-a-walking-intervention-for-people-with-recurrent-or-metastatic-cancer
#7
Vicki Tsianakas, Jenny Harris, Emma Ream, Mieke Van Hemelrijck, Arnie Purushotham, Lorelei Mucci, James S A Green, Jacquetta Fewster, Jo Armes
OBJECTIVES: Walking is an adaptable, inexpensive and accessible form of physical activity. However, its impact on quality of life (QoL) and symptom severity in people with advanced cancer is unknown. This study aimed to assess the feasibility and acceptability of a randomised controlled trial (RCT) of a community-based walking intervention to enhance QoL in people with recurrent/metastatic cancer. DESIGN: We used a mixed-methods design comprising a 2-centre RCT and nested qualitative interviews...
February 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28198989/the-effects-of-health-education-given-by-nurses-to-copd-patients-on-the-daily-oxygen-concentrator-usage-time
#8
Uğur Doğan, Nimet Ovayolu
INTRODUCTION: Long-term oxygen therapy is the most effective method which has been shown to prolong the lifespan in people with COPD. The aim of the study was to investigate the effects of health education given by nurses to patients with COPD on the daily oxygen concentrator (OC) usage time. MATERIAL AND METHODS: The study was carried out in a State Hospital, Turkey, between July and November 2015. After given consent to the study, participants were divided into intervention and control groups by simple random sampling method...
2017: Adv Respir Med
https://www.readbyqxmd.com/read/28197692/feasibility-of-establishing-an-australian-acl-registry-a-pilot-study-by-the-australian-orthopaedic-association-national-joint-replacement-registry-aoanjrr
#9
Christina Lekkas, Richard Clarnette, Stephen E Graves, Sophia Rainbird, David Parker, Michelle Lorimer, Roger Paterson, Justin Roe, Hayden Morris, Julian A Feller, Peter Annear, Ben Forster, David Hayes
PURPOSE: Rupture of the anterior cruciate ligament (ACL) is a common and debilitating injury that impacts significantly on knee function and risks the development of degenerative arthritis. The outcome of ACL surgery is not monitored in Australia. The optimal treatment is unknown. Consequently, the identification of best practice in treating ACL is crucial to the development of improved outcomes. The Australian Knee Society (AKS) asked the Australian Orthopaedic Association (AOA) to consider establishing a national ACL registry...
February 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28196575/workplace-violence-against-nurses-vhembe-district-hospitals-south-africa
#10
Tshifularo Olga Mahani, Henry Abayomi Akinsola, Jabu Mabunda, Helen Tosin Oni
INTRODUCTION: Work-related violence is a common problem worldwide. In South Africa, the Medical Research Council conducted a study on workplace violence in the health care industry and reported that most respondents had experienced it in different forms. PURPOSE: This study aimed to identify the types and causes of workplace violence toward nurses in Thulamela hospitals, Vhembe district. METHODS: The study employed a quantitative approach using a cross-sectional design...
February 1, 2017: Research and Theory for Nursing Practice
https://www.readbyqxmd.com/read/28191349/video-assisted-informed-consent-for-cataract-surgery-a-randomized-controlled-trial
#11
Yuehong Zhang, Xiangcai Ruan, Haoying Tang, Weizhong Yang, Zhuanhua Xian, Min Lu
Purpose. To investigate whether adding video assistance to traditional verbal informed consent advisement improved satisfaction among cataract surgery patients. Methods. This trial enrolled 80 Chinese patients with age-related cataracts scheduled to undergo unilateral phacoemulsification surgery. Patients were randomized into two groups: the video group watched video explaining cataract-related consent information and rewatched specific segments of the video at their own discretion, before receiving traditional verbal consent advisement; the control group did not watch the video...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28187903/the-influence-of-trocar-fenestration-and-volume-on-connective-tissue-progenitor-cells-stem-cells-in-arthroscopic-bone-marrow-aspiration-from-the-proximal-humerus
#12
Andreas Voss, Mary Beth McCarthy, Hardeep Singh, Knut Beitzel, Jessica DiVenere, Mark P Cote, Alexander R Hoberman, Michael Nowak, Andreas B Imhoff, Augustus D Mazzocca
PURPOSE: To evaluate the number of connective tissue progenitor cells (CTPs) and nucleated cells obtained during bone marrow aspiration (BMA) from the proximal humerus using either a fenestrated or a nonfenestrated trocar and determine differences in varying amounts of aspiration volume. The first hypothesis was that the number of CTPs extracted with the fenestrated trocar would be greater due to its potential to extract more cells through its fenestrations. The second hypothesis was that using consecutive aspirations with either trocar would provide a consistent number of CTPs and nucleated cells throughout the aspiration with no significant decrease of cells at the end...
February 7, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28176639/personalized-medicine-in-the-paediatric-population-the-balance-between-pharmacogenetics-progress-and-bioethics
#13
Stefania Schiavone, Margherita Neri, Cristoforo Pomara, Irene Riezzo, Luigia Trabace, Emanuela Turillazzi
Personalized medicine (PM) is becoming increasingly important in contemporary clinical and research scenarios. In the context of PM, pharmacogenomics and pharmacogenetics are aimed at the genetic personalization of drug response. Extrinsic and intrinsic factors may explain inter-individual variability in drug response. Among such factors, age seems to specifically intervene to modulate drug response since normal developmental changes may influence the exposure-response relation. Consequently, the potential benefit of pharmacogenomics (PGx) in the paediatric population is considerable...
February 7, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28173855/burden-screening-and-treatment-of-depressive-and-anxious-symptoms-among-women-referred-to-cardiac-rehabilitation-a-prospective-study
#14
Megan C Hurley, Heather M Arthur, Caroline Chessex, Paul Oh, Karam Turk-Adawi, Sherry L Grace
BACKGROUND: Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality among women. Women with CVD experience a greater burden of psychosocial distress than men, and practice guidelines promote screening in cardiac patients, especially women. The objectives herein were to describe the burden of psychosocial distress, extent of screening, forms of treatment, and whether receipt of treatment was related to psychosocial distress symptom severity at follow-up, among women...
February 7, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28165540/attitudes-towards-organ-donation-and-relation-to-wish-to-donate-posthumously
#15
Julius Weiss, David Shaw, Roger Schober, Viviana Abati, Franz F Immer, Comité National du Don d'Organes Cndo
BACKGROUND: Organs donated for transplantation remain a scarce resource in Switzerland. One of the reasons for this situation is the high percentage of patients or families who refuse to consent to donation. This study aimed to provide an overview of attitudes towards organ donation among Swiss residents, including any intention to donate organs after death, and whether they had already declared their wish and/or communicated it to anyone. METHODS: A representative poll investigating the attitude of the Swiss population towards deceased organ donation was conducted between 16 and 28 March 2015...
February 6, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28159027/intimate-partner-violence-screening-and-the-comparative-effects-of-screening-mode-on-disclosure-of-sensitive-health-behaviours-and-exposures-in-clinical-settings
#16
T Frazier, K M Yount
OBJECTIVE: Detecting sensitive health information in clinical settings is of scientific and practical importance. The purpose of this study was to determine whether mode of screening influenced disclosure of intimate partner violence (IPV) in patterns similar to other forms of sensitive information. STUDY DESIGN: This cross sectional study was designed to compare effects of face-to-face vs computer self-assessment for sensitive health information on disclosure rates...
February 2017: Public Health
https://www.readbyqxmd.com/read/28155094/ethical-implications-of-user-perceptions-of-wearable-devices
#17
REVIEW
L H Segura Anaya, Abeer Alsadoon, N Costadopoulos, P W C Prasad
Health Wearable Devices enhance the quality of life, promote positive lifestyle changes and save time and money in medical appointments. However, Wearable Devices store large amounts of personal information that is accessed by third parties without user consent. This creates ethical issues regarding privacy, security and informed consent. This paper aims to demonstrate users' ethical perceptions of the use of Wearable Devices in the health sector. The impact of ethics is determined by an online survey which was conducted from patients and users with random female and male division...
February 2, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28152801/improving-the-quality-of-the-consenting-and-education-process-for-patients-starting-on-oral-oncology-medications
#18
Jessica Ashford, David Bivens
: 82 Background: Oral oncology medication prescribing is on the rise nationwide. Given that these medications are self-administered, drug compliance is a concern. Appropriate patient education directly impacts drug adherence. Prior to the process improvement initiative in our community based medical oncology clinic, implied consent was obtained while educating patients on side effects and written informed consent was documented 0% of the time. This creates a patient safety and risk management problem...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152683/hiv-testing-in-a-cancer-center-emergency-department
#19
Kelly W Merriman, Zeena Shelal, Hadil Bazerbashi, Patricia A Brock, Carmen E Gonzalez, Harrys A Torres, Terry Rice
: 225 Background: HIV is a cancer-associated virus classically associated with KS, NHL, and cervical cancer, but more recently with anal cancer, lung, and head and neck cancers. HIV testing and treatment are important for cancer patients for three reasons: 1) HIV treatment is associated with reduced transmission of a cancer-associated virus. 2) HIV treatment is associated with improved outcomes of cancer therapy in many cancers. 3) HIV testing optimizes quality of care, since testing is recommended by the Centers for Disease Control and Prevention (CDC) and the US Preventive Services Task Force (USPSTF)(A level recommendation) for patients between the ages of 15 and 65 years of age...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150503/yoga-program-for-high-grade-glioma-patients-undergoing-radiotherapy-and-their-family-caregivers
#20
Kathrin Milbury, Smitha Mallaiah, Anita Mahajan, Terri Armstrong, Shioa-Pei Weathers, Kathryn E Moss, Nazli Goktepe, Amy Spelman, Lorenzo Cohen
BACKGROUND: Despite their high symptom burden and poor prognosis, evidence-based supportive care interventions for adults with high-grade glioma (HGG) and their caregivers are lacking. Thus, we aimed to establish feasibility of a patient-caregiver dyadic yoga program (DYP) for newly diagnosed HGG patients and their family caregivers targeting quality-of-life (QOL) outcomes. METHOD: In this single-arm pilot trial, dyads participated in a 12-session DYP program across the course of patients' radiotherapy...
January 1, 2017: Integrative Cancer Therapies
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