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https://www.readbyqxmd.com/read/29622159/device-related-thrombosis-after-percutaneous-left-atrial-appendage-occlusion-for-atrial-fibrillation
#1
Laurent Fauchier, Alexandre Cinaud, François Brigadeau, Antoine Lepillier, Bertrand Pierre, Selim Abbey, Marjaneh Fatemi, Frederic Franceschi, Paul Guedeney, Peggy Jacon, Olivier Paziaud, Sandrine Venier, Jean Claude Deharo, Daniel Gras, Didier Klug, Jacques Mansourati, Gilles Montalescot, Olivier Piot, Pascal Defaye
BACKGROUND: Transcatheter left atrial appendage (LAA) occlusion is an alternative strategy for stroke prevention in patients with atrial fibrillation (AF). OBJECTIVES: This study sought to determine the incidence, predictors, and prognosis of thrombus formation on devices in patients with AF who were treated with LAA closure. METHODS: The study retrospectively analyzed data from patients treated with 2 LAA closure devices seen in 8 centers in France from February 2012 to January 2017...
April 10, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29564664/long-term-outcomes-following-percutaneous-left-atrial-appendage-closure-in-patients-with-atrial-fibrillation-and-contraindications-to-anticoagulation
#2
Ander Regueiro, Ignacio Cruz-Gonzalez, Armando Bethencourt, Luis Nombela-Franco, Jean Champagne, Luis Asmarats, Pilar Jiménez-Quevedo, Tania Rodriguez-Gabella, Juan Carlos Rama-Merchan, Rishi Puri, Gilles O'Hara, Josep Rodés-Cabau
PURPOSE: We aimed to evaluate the late clinical outcomes of percutaneous LAA closure in patients with atrial fibrillation (AF) and contraindication to oral anticoagulation. METHODS: Consecutive AF patients with contraindications to oral anticoagulation who underwent successful LAA closure between December 2008 and March 2013 at four centers were included. RESULTS: A total of 101 patients (median age 76 [IQR 69-80] years, 48% women, mean CHA2 DS2 -VASc 5 ± 2; HAS-BLED 4 ± 1) were included...
March 21, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29564543/impact-of-chronic-kidney-disease-on-watchman-implantation-experience-with-300-consecutive-left-atrial-appendage-closures-at-a-single-center
#3
Xin Xue, Lisheng Jiang, Erich Duenninger, Manuela Muenzel, Shaofeng Guan, Adam Fazakas, Fanzhou Cheng, Juergen Illnitzky, Thorsten Keil, Jiangtao Yu
The prevalence of chronic kidney disease (CKD) is high in patients with atrial fibrillation (AF). Left atrial appendage closure (LAAC) has been recognized as an efficient alternative to oral anticoagulation for the prevention of thromboembolic events in patients with non-valvular AF (NVAF); however, the long-term safety and efficacy of LAAC in patients with CKD remain unclear. This study was designed to provide data regarding the safety and efficacy of LAAC in NVAF patients with CKD. A real-world analysis of the safety and efficacy of LAAC was performed on a cohort of 300 NVAF patients with or without CKD who underwent LAAC using the Watchman (WM) device at our center...
March 22, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29540492/percutaneous-left-atrial-appendage-closure-is-a-reasonable-option-for-patients-with-atrial-fibrillation-at-high-risk-for-cerebrovascular-events
#4
Emmanuel Teiger, Jean-Benoit Thambo, Pascal Defaye, Jean-Sylvain Hermida, Sélim Abbey, Didier Klug, Jean-Michel Juliard, Jean-Luc Pasquie, Gilles Rioufol, Antoine Lepillier, Meyer Elbaz, Jerome Horvilleur, Philippe Brenot, Bertrand Pierre, Philippe Le Corvoisier
BACKGROUND: Percutaneous left atrial appendage (LAA) closure is an emerging option for patients with atrial fibrillation at high risk for cerebrovascular events. The multicenter FLAAC registry (French Nationwide Observational LAA Closure Registry) was established to assess LAA closure outcomes in everyday practice. METHODS AND RESULTS: Four hundred thirty-six patients referred from April 2013 to September 2015 to 33 French interventional cardiology centers for percutaneous LAA closure were included prospectively in the FLAAC registry...
March 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29526293/left-atrial-appendage-occlusion-the-current-device-landscape-and-future-perspectives
#5
REVIEW
Ignacio Cruz-Gonzalez, Monica Fuertes-Barahona, Jose C Moreno-Samos, Rocio Gonzalez-Ferreiro, Yan Yin Lam, Pedro L Sanchez
Since the first percutaneous left atrial appendage occlusion (LAAO), many studies have shown the safety and efficacy of this technique to prevent embolic strokes in nonvavular atrial fibrillation. The design, characteristics, and clinical data of the most frequently used devices for LAAO are reviewed, including the Amplatzer cardiac plug and Amulet (Abbott Vascular), the Watchman (Boston Scientific), and the LARIAT device (SentreHEART). Similarly, newer closer devices, such as Ultraseal (Cardia), LAmbre (Lifetech), and Coherex WaveCrest (Johnson & Johnson), are also discussed...
April 2018: Interventional Cardiology Clinics
https://www.readbyqxmd.com/read/29526288/the-watchman-left-atrial-appendage-closure-device-technical-considerations-and-procedural-approach
#6
REVIEW
Matthew J Price
Randomized clinical trials have demonstrated that left atrial appendage (LAA) closure with the WATCHMAN device provides stroke prevention in nonvalvular atrial fibrillation while significantly reducing morality and major bleeding. Technical and procedural considerations are paramount for the therapeutic success. Maximizing procedural safety is critical. Optimal LAA sealing is required. Improvements in procedural technique and operator training have resulted in a marked reduction in adverse procedural events, which should increase the absolute long-term clinical benefit...
April 2018: Interventional Cardiology Clinics
https://www.readbyqxmd.com/read/29526284/history-of-percutaneous-left-atrial-appendage-occlusion-with-amplatzer-devices
#7
REVIEW
Bernhard Meier, Wim Stegink, Apostolos Tzikas
AMPLATZER devices preceded WATCHMAN occluder in 2002 for catheter-based left atrial appendage occlusion. The AMPLATZER technique facilitates simultaneous closure of atrial shunts using two devices through one gear. Randomized WATCHMAN follow-up data showed a mortality benefit over warfarin. AMPLATZER data make this likely valid for the strategy. Particularly young people with atrial fibrillation should be offered left atrial appendage occlusion because the risk is confined to the intervention and early postintervention period...
April 2018: Interventional Cardiology Clinics
https://www.readbyqxmd.com/read/29526283/a-history-of-left-atrial-appendage-occlusion
#8
REVIEW
David R Holmes, Robert S Schwartz, George G Latus, Robert A Van Tassel
A new era in antiembolic therapy has been initiated by the growing numbers of device-based therapies. Early concerns surrounding eliminating this enigmatic structure have not proven true. Other benefits are being further evaluated. Many other questions remain, such as whether there is a device-specific outcome effect or whether it is a class effect. Other questions include other devices, what head-to-head studies will show, and the impact of residual leak. Left atrial appendage using the Watchman ablation strategy can reduce cardioembolic stroke, with comparable or fewer adverse effects by device technology than obtained by long-term anticoagulation with its attendant bleeding risks...
April 2018: Interventional Cardiology Clinics
https://www.readbyqxmd.com/read/29525913/percutaneous-left-atrial-appendage-closure-with-watchman%C3%A2-device-peri-procedural-and-mid-term-outcomes-from-the-traps-registry
#9
Patrizio Mazzone, Giuseppe D'Angelo, Damiano Regazzoli, Giulio Molon, Gaetano Senatore, Salvatore Saccà, Guido Canali, Claudia Amellone, Riccardo Turri, Paolo Della Bella
PURPOSE: The WATCHMAN device for Left Atrial Appendage Occlusion (LAAO) has proven to be an effective alternative to oral anticoagulation (OAC) in patients with atrial fibrillation (AF), and has now been adopted in clinical practice. In the present study, we analyzed the safety and efficacy profile of the LAAO procedure at mid-term follow-up. METHODS: The TRAPS Registry is an observational, multicenter registry involving four Italian centers. Consecutive patients who had undergone LAAO with WATCHMAN device were enrolled...
March 10, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29475536/multiple-thromboembolic-events-from-a-left-atrial-appendage-occlusion-device
#10
Graeme Prosperi-Porta, Gregory Schnell, Jillian Colbert, Angela Franko, Stephen B Wilton, Vikas P Kuriachan
Left atrial appendage occlusion devices are an alternative to oral anticoagulation in patients with nonvalvular atrial fibrillation who are at risk of ischemic stroke. Thromboprophylaxis after implantation is recommended, but the optimal regimen is unknown. We report a clinicopathologic case in which thrombus adherent to an incompletely endothelialized WATCHMAN device (Boston Scientific, Marlborough, MA) resulted in multiple thromboembolic events, contributing to a fatal outcome. This case illustrates uncertainties regarding the device's endothelialization process...
March 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29463510/device-thrombosis-after-percutaneous-left-atrial-appendage-occlusion-is-related-to-patient-and-procedural-characteristics-but-not-to-duration-of-postimplantation-dual-antiplatelet-therapy
#11
Radoslaw Pracon, Sripal Bangalore, Zofia Dzielinska, Marek Konka, Cezary Kepka, Mariusz Kruk, Edyta Kaczmarska-Dyrda, Joanna Petryka-Mazurkiewicz, Sebastian Bujak, Mateusz Solecki, Agnieszka Pskit, Agnieszka Dabrowska, Bartosz Sieradzki, Andrzej Plonski, Witold Ruzyllo, Adam Witkowski, Marcin Demkow
BACKGROUND: Device-related thrombus (DRT) after left atrial appendage occlusion is a worrisome finding with little knowledge about when to expect it and how to prevent it. This study sought to investigate correlates of DRT after left atrial appendage occlusion, its time of diagnosis, and particularly, association with postimplantation dual antiplatelet therapy duration. METHODS AND RESULTS: Consecutive patients (n=102) after left atrial appendage occlusion with AMPLATZER Cardiac Plug/Amulet (n=59) or WATCHMAN (n=43) were included in a prospective registry (October 2011-May 2016)...
March 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29454726/successful-percutaneous-retrieval-of-a-33-mm-watchman-left-atrial-appendage-occlusion-device-from-the-left-atrium
#12
Hai-Ying Li, Xin-Lei Wu, Fang-Yi Xiao, Xiao-Dong Zhou, Ye Chen, Wei-Jian Huang
No abstract text is available yet for this article.
February 8, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29453694/percutaneous-left-atrial-appendage-occlusion-in-the-prevention-of-stroke-in-atrial-fibrillation-a-systematic-review
#13
REVIEW
Jayson R Baman, Moussa Mansour, E Kevin Heist, David T Huang, Yitschak Biton
Atrial fibrillation is commonly coexistent with heart failure, and the management of the heart failure patient would be incomplete without an appreciation for atrial fibrillation management. There are many complications associated with oral anticoagulation in the prevention of stroke related to atrial fibrillation. In recent years, the advent of several percutaneous left atrial appendage (LAA) occlusion/closure strategies has sought to provide an alternative treatment modality. Here, we systematically review the published literature to investigate the efficacy and safety of percutaneous LAA occlusion/closure devices...
February 17, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29453212/implant-of-a-left-atrial-appendage-occluder-device-watchman-and-leadless-pacing-system-micra-through-the-same-venous-access-in-a-single-sitting
#14
Sofian Johar, Nazar Luqman
A left atrial appendage occluder device (Watchman) and leadless pacemaker (Micra) was implanted from a single right femoral vein access in a 73-year-old female patient with persistent atrial fibrillation and symptomatic tachy-brady syndrome and unable to take oral anticoagulants. Standard methods of implantation were followed for both procedures. The Watchman device was implanted first followed by dilatation of the same venous access site in order to implant Micra transcatheter pacing system. The patient tolerated the procedures well and there were no complications...
February 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29415203/left-atrial-appendage-patency-and-device-related-thrombus-after-percutaneous-left-atrial-appendage-occlusion-a-computed-tomography-study
#15
Hubert Cochet, Xavier Iriart, Soumaya Sridi, Claudia Camaioni, Olivier Corneloup, Michel Montaudon, François Laurent, Wieme Selmi, Pauline Renou, Zakaria Jalal, Jean-Benoît Thambo
Aims: Transoesophageal echocardiography studies have reported frequent peri-device leaks and device-related thrombi (DRT) after percutaneous left atrial appendage (LAA) occlusion. We assessed the prevalence, characteristics and correlates of leaks and DRT on cardiac computed tomography (CT) after LAA occlusion. Methods and results: Consecutive patients underwent cardiac CT before LAA occlusion to assess left atrial (LA) volume, LAA shape, and landing zone diameter...
February 2, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29411147/atrial-fibrillation-for-the-neurologist-preventing-both-ischemic-and-hemorrhagic-strokes
#16
REVIEW
Elif Gokcal, Marco Pasi, Marc Fisher, M Edip Gurol
PURPOSE OF REVIEW: This review aims to help neurologists managing atrial fibrillation (AF) patients who had an ischemic stroke and/or with intracranial hemorrhage (ICH) markers, therefore at high embolic/hemorrhagic risks. RECENT FINDINGS: Implantable loop recorders have substantially improved the accuracy of AF detection. Recent research yielded a set of powerful neuroimaging markers that can stratify ICH risk. Direct oral anticoagulants (DOAC) are easier to use with a lower ICH risk than warfarin in a general AF population...
February 6, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29385439/emergent-surgical-removal-of-a-migrated-left-atrial-appendage-occluder
#17
Mohamed El-Gabry, Sharaf-Eldin Shehada, Daniel Wendt, Fanar Mourad
Occlusion of the left atrial appendage (LAA) in patients with atrial fibrillation has become a standard therapy to prevent thromboembolic complications. We aim to present 3 cases of LAA occluder embolization after percutaneous WATCHMAN™ device implantation, which required emergent surgical retrieval. The device was dislocated in the left atrium, introducing LAA perforation and resulting in pericardial effusion and later tamponade in 1 patient who developed multiorgan failure and died 8 days postoperatively...
January 29, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29381951/watchman-device-related-thrombus-successfully-treated-with-apixaban-a-case-report
#18
Chun-Ka Wong, Pak-Hei Chan, Cheung-Chi Lam, On-Hing Kwok, Yat-Yin Lam, Chung-Wah Siu
RATIONALE: Among atrial fibrillation patients with high risk of bleeding, left atrial appendage occlusion has emerged as an alternative to long-term oral anticoagulation therapy for stroke prevention. Device-related thrombus remains a major concern because it may result in recurrent embolic events. To date, there is no consensus on the optimal method of treating device-related-thrombus. PATIENT CONCERNS: A 78-year-old man with atrial fibrillation had an episode of intracranial hemorrhage while taking warfarin...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29379717/cryoballoon-pulmonary-vein-isolation-and-voltage-mapping-for-symptomatic-atrial-fibrillation-9-months-after-watchman-device-implantation
#19
Henry D Huang, Viren M Patel, Parikshit S Sharma, Zenith Jameria, Sorin Lazar, Richard Trohman, Erik Wissner
No abstract text is available yet for this article.
January 2018: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/29374188/impact-of-left-atrial-appendage-morphology-on-thrombus-formation-after-successful-left-atrial-appendage-occlusion-assessment-with-cardiac-computed-tomography
#20
Wulf Dieker, Michael Behnes, Christian Fastner, Benjamin Sartorius, Annika Wenke, Ishar Sing-Gill, Ibrahim El-Battrawy, Jürgen Kuschyk, Theano Papavassiliu, Ursula Hoffmann, Kambis Mashayekhi, Stefan O Schoenberg, Martin Borggrefe, Thomas Henzler, Ibrahim Akin
A standardized imaging algorithm by cardiac computed tomography angiography (cCTA) (LOVE-view) was used in 30 patients to evaluate the influence of different left atrial appendage (LAA) morphologies on development of thrombosis in the LAA 6 months after implantation of an occlusion device (Watchman or Amplatzer-Cardiac-Plug) in patients with non-valvular atrial fibrillation, CHA2DS2-VASc-Score >1 and a contraindication for oral anticoagulation. The distribution of different LAA morphologies was 40% windsock, 17% broccoli and 43% chicken wing type...
January 26, 2018: Scientific Reports
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