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Joshua R Hancock, Sean P Place
As we move into the Anthropocene, organisms inhabiting marine environments will continue to face growing challenges associated with changes in ocean pH (ocean acidification), dissolved oxygen (dead zones) and temperature. These factors, in combination with naturally variable environments such as the rocky intertidal zone, may create extreme physiological challenges for organisms that are already performing near their biological limits. Although numerous studies have examined the impacts of climate-related stressors on intertidal animals, little is known about the underlying physiological mechanisms driving adaptation to ocean acidification and how this may alter organism interactions, particularly in marine vertebrates...
2016: Conservation Physiology
Liang Xu, Xingbin Huang, Wenjiang Dai, Punan Sun, Xuanlin Chen, Limin An
CdSe quantum dots (QDs) and polyaniline (PAni) were mixed to prepare CdSe QDs/PAni complex. PAni can quench the fluorescence of CdSe QDs. Fluorescence intensity of CdSe QDs/PAni complex is related to the size of CdSe QDs and the concentration of PAni. UV-Vis absorption spectra, fluorescence spectra, time-resolved fluorescence spectroscopy were used to analys the quenching phenomenon. The mechanism of fluorescence quenching is dependent on two factors: on one hand, the Förster resonance energy transfer from CdSe to PAni; on the other hand, PAni can intercept the charge relaxation process of CdSe and lead to the interruption of radiative recombination...
April 2016: Journal of Nanoscience and Nanotechnology
P C S Araújo, A P Lourenço, A Raw
Species richness and seasonal abundance of solitary bees were investigated in rocky, montane grassland (campo rupestre) (1180 m asl) and cerrado sensu stricto (680 m asl) in the Biribiri State Park, Diamantina, state of Minas Gerais, Brazil. Three hundred nineteen nest traps of bamboo canes and black cardboard tubes were monthly inspected at each site during 15 months. A total of eight species of bees built 97 nests. Four species were common to both sites. Tetrapedia aff. curvitarsis Friese and Tetrapedia aff...
May 3, 2016: Neotropical Entomology
Meisam Jafarzadeh, Bahram M Soltani
OBJECTIVE: SMAD proteins are the core players of the transforming growth factor-beta (TGFβ) signaling pathway, a pathway which is involved in cell proliferation, differentiation and migration. On the other hand, hsa-miRNA-590-5p (miR-590-5p) is known to have a negative regulatory effect on TGFβ signaling pathway receptors. Since, RNAhybrid analy- sis suggested SMAD3 as a bona fide target gene for miR-590, we intended to investigate the effect of miR-590-5p on SMAD3 transcription. MATERIALS AND METHODS: In this experimental study, miR-590-5p was overexpressed in different cell lines and its increased expression was detected through quantitative reverse transcription-polymerase chain reaction (RT-qPCR)...
2016: Cell Journal
Y H Lee, G G Song
The aim of this study was to explore whether vascular endothelial growth factor (VEGF) polymorphisms confer susceptibility to psoriasis. Meta-analyses were conducted to examine the associations between the +405 C/G, -460 C/T, -1154 A/G, and -2578 A/C polymorphisms of VEGF and psoriasis using allele contrast and recessive, dominant, and additive models. Seven studies on VEGF polymorphisms and psoriasis involving 1956 subjects (psoriasis patients 665, controls 1291) were included in this meta-analysis. We observed no association between psoriasis and the VEGF +405 C allele in all study subjects (odds ratio = 0...
2015: Genetics and Molecular Research: GMR
Walicyranison Plinio da Silva-Rocha, Diana Luzia Zuza-Alves, Analy Salles de Azevedo Melo, Guilherme Maranhão Chaves
Fungal peritonitis is a rare serious complication most commonly observed in immunocompromised patients under peritoneal dialysis. Nevertheless, this clinical condition is more difficult to treat than bacterial peritonitis. Bacterial peritonitis followed by the use of antibiotics is the main risk factor for developing fungal peritonitis. Candida spp. are more frequently isolated, and the isolation of filamentous fungi is only occasional. Here we describe a case of Fusarium solani species complex peritonitis associated with bacterial peritonitis in a female kidney transplant recipient with previous history of nephrotic syndrome...
December 2015: Mycopathologia
F Llopis Roca, A Juan Pastor, C Ferré Losa, J González Del Castillo, M Ruiz Grinspan, M Martínez Ortíz de Zárate
BACKGROUND: To study the clinical characteristics of patients with infection attending the emergency department (ED) and compare those admitted to a short stay unit (SSU) with those admitted to a conventional hospital ward (CHW). METHODS: A descriptive multicenter cross-sectional analysis of infected patients requiring admission from 10 ED with SSU. Data were collected for age, gender, comorbidities, risk factors for multiresistant pathogens, type of infection, sepsis criteria, microbiology and antibiotic treatment...
January 2015: Anales del Sistema Sanitario de Navarra
Anali Galluce Torina, Karla Reichert, Fany Lima, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Helison Rafael Pereira do Carmo, Daniela Diógenes de Carvalho, Mário José Abdalla Saad, Andrei Carvalho Sposito, Orlando Petrucci
BACKGROUND: The inflammatory response has been implicated in the pathogenesis of left ventricular (LV) remodeling after myocardial infarction (MI). An anthraquinone compound with anti-inflammatory properties, diacerein inhibits the synthesis and activity of pro-inflammatory cytokines, such as tumor necrosis factor and interleukins 1 and 6. The purpose of this study was to investigate the effects of diacerein on ventricular remodeling in vivo. METHODS AND RESULTS: Ligation of the left anterior descending artery was used to induce MI in an experimental rat model...
2015: PloS One
Mohammad Reza Zand Karimi, Reza Faridhosseini, Mohammad Reza Abbaszadegan, Farrahzad Jabbari Azad, Afshin Shirkani, Anali Riyahi, Mehdi Montazar, Mehran Gholamin
OBJECTIVES: Asthma results from the interaction between genetic and environmental factors. ADAM33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness. MATERIALS AND METHODS: This is a case-control study, where four SNPs S1 (rs3918396), T1 (rs2280091), T2 (rs2280090), V4 (rs2787094) of ADAM33 gene have been assessed in patients with allergic asthma and normal controls (95 patients and 86 normal). Blood samples of these participants have been genotyped by PCR and the RFLP method...
September 2014: Iranian Journal of Basic Medical Sciences
Carolina M Silva, Ana M R Carvalho-Parahym, Danielle P C Macêdo, Reginaldo G Lima-Neto, Elaine C Francisco, Analy S A Melo, Maria da Conceição M Silva, Moacir B Jucá, Luciana R B Mello, Rosemary M J Amorim, Rejane P Neves
Candidemia is a frequent condition in Neonatal Intensive Care Units (NICU) and usually complicates the newborns clinical course. Several factors are responsible for candidiasis, such as prematurity and use of broad-spectrum antibiotics, and in these cases, there are the involvement of various Candida species, as C. albicans, and C. parapsilosis. However, other species as C. haemulonii has been rarely described in candidemia cases, being considered an emergent pathogen. Thus, we report a case of neonatal candidemia by C...
August 2015: Mycopathologia
Xiao Han, Miao Ge, Jie Dong, Zixuan Wang, Jinwei He, Rongrong Yang
The study focused on the relationship between geographical factors and left ventricular myocardial performance index (MPI)reference value, analyed the different distribution of MPI, and then provided a scientific basis for clinical examination. This study collected MPI reference values of 2545 healthy women from 91 cities in China, used the Moran's index to determin the spatial relationship, selected 25 geographical factors, examined the significance between MPI and geographical factors by correlation analysis, through the significance test, and extracted seven significant factors to build the artificial neural network (ANN) model and principal component analysis (PCA) model...
November 2015: International Journal of Biometeorology
Vladimír Bencko, Chao Chen
Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analy- sis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties...
September 2014: Central European Journal of Public Health
Vladimír Bencko, Chao Chen
Cessation lag and lingering effect are two important aspects of risk assessment, and have potential applications to dose-response analysis in risk assessment. In addition to providing insight into biological mode of action, the concept of cessation lag is useful for economic benefit analy- sis. Concept of effect lingering can be used to analyze epidemiological data by uncovering the hidden biological implications related to disease endpoints, thereby advancing current efforts to characterize and reduce risk assessment uncertainties...
September 2014: Central European Journal of Public Health
L Muraro, R S White
OBJECTIVE: Canine ovariohysterectomy (OVH) is one of the most commonly performed surgical procedures in companion animal practice. The aim of the study was to determine the frequency and types of complications related to OVH. MATERIAL AND METHODS: The clinical records of all street dogs admitted to the public dog shelters of the Veneto Region (Italy) between January 2010 and December 2011 were reviewed for dogs that had undergone OVH. Specific comparison was made between anaesthesia time, body weight of the patients and intra- and postoperative complications (occurring up to 4 weeks postoperatively)...
2014: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
Yu Lin, Yongqun He
BACKGROUND: Due to human variations in genetic susceptibility, vaccination often triggers adverse events in a small population of vaccinees. Based on our previous work on ontological modeling of genetic susceptibility to disease, we developed an Ontology of Genetic Susceptibility Factors (OGSF), a biomedical ontology in the domain of genetic susceptibility and genetic susceptibility factors. The OGSF framework was then applied in the area of vaccine adverse events (VAEs). RESULTS: OGSF aligns with the Basic Formal Ontology (BFO)...
2014: Journal of Biomedical Semantics
Karla Reichert, Helison Rafael Pereira do Carmo, Fany Lima, Anali Galluce Torina, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Lindemberg Mota Silveira Filho, Elaine Soraya Barbosa de Oliveira Severino, Orlando Petrucci
INTRODUCTION: Myocardial preservation during open heart surgeries and harvesting for transplant are of great importance. The heart at the end of procedure has to resume its functions as soon as possible. All cardioplegic solutions are based on potassium for induction of cardioplegic arrest. OBJECTIVE: To assess a cardioplegic solution with no potassium addition to the formula with two other commercially available cardioplegic solutions. The comparative assessment was based on cytotoxicity, adenosine triphosphate myocardial preservation, and caspase 3 activity...
October 2013: Revista Brasileira de Cirurgia Cardiovascular
Mohammad N Rezaei, Emmie Dornez, Pieter Jacobs, Anali Parsi, Kevin J Verstrepen, Christophe M Courtin
Fermentation of sugars into CO2, ethanol and secondary metabolites by baker's yeast (Saccharomyces cerevisiae) during bread making leads to leavening of dough and changes in dough rheology. The aim of this study was to increase our understanding of the impact of yeast on dough related aspects by investigating the effect of harvesting yeast at seven different points of the growth profile on its fermentation performance, metabolite production, and the effect on critical dough fermentation parameters, such as gas retention potential...
May 2014: Food Microbiology
L Katherine Kirkman, Analie Barnett, Brett W Williams, J Kevin Hiers, Scottrr M Pokswinski, Robert J Mitchell
The use of reference models as templates of historical or natural conditions to assess restoration progress is inherently logical; however, difficulties occur in application because of the need to incorporate temporal variation in ecosystems caused by disturbance and succession, as well as seasonal, interannual, or decadal variability. The landscape-scale restoration of the globally threatened and fire-dependent longleaf pine ecosystem in the southeastern United States is an example in which restoration efforts are even more complicated by the limited availability of extant reference sites...
October 2013: Ecological Applications: a Publication of the Ecological Society of America
Rafael A Oechsler, Tiago M Yamanaka, Paulo Jm Bispo, Juliana Sartori, Maria Cecilia Zorat Yu, Analy Salles A Melo, Darlene Miller, Ana Luisa Hofling-Lima
BACKGROUND: The purpose of this paper is to describe clinical characteristics and determine correlations between clinical outcomes and antifungal susceptibility among molecularly characterized ocular Fusarium isolates in Brazil. METHODS: Forty-one Fusarium isolates obtained from 41 eyes of 41 patients were retrieved from the ophthalmic microbiology laboratory at São Paulo Federal University and grown in pure culture. These isolates were genotyped and antifungal susceptibilities determined for each isolate using a broth microdilution method...
2013: Clinical Ophthalmology
C F Martins, R P Ferreira, L T Carneiro
The use of trap nests supplies important biological information concerning the biology of bees and wasps. However, the knowledge about the factors that influence the management of these groups is still scarce. Our study aimed to analyze the effects of the orientation of nest entrance, shading, and block material (wood or vermiculite) on the frequency, richness, and composition of trap-nesting species at two agricultural areas in the Atlantic Forest region of the state of Paraiba. Both sites showed similar species richness and composition...
April 2012: Neotropical Entomology
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