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https://www.readbyqxmd.com/read/28819801/botulinum-toxin-treatment-in-multiple-sclerosis-a-review
#1
REVIEW
Yasaman Safarpour, Tahereh Mousavi, Bahman Jabbari
Purpose of review The purpose of this review is to provide updated information on the role of botulinum neurotoxin (BoNT) therapy in multiple sclerosis (MS). This review aims to answer which symptoms of multiple sclerosis may be amenable to BoNT therapy. Recent findings We searched the literature on the efficacy of BoNTs for treatment of MS symptoms up to April 1st 2017 via the Yale University Library's search engine including but not limited to Pub Med and Ovis SP. The level of efficacy was defined according to the assessment's criteria set forth by the Subcommittee on Guideline Development of the American Academy of Neurology...
August 17, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28802070/memantine-for-the-treatment-of-general-neuropathic-pain-a-narrative-review
#2
REVIEW
Gisèle Pickering, Véronique Morel
Neuropathic pain (NP) is difficult to treat and is associated with a decline in quality of life. NP aetiologies are numerous and a number of pathologies display neuropathic characteristics. Of the various N-Methyl-D-Aspartate antagonists that are alternatives to recommended in first-line NP treatment, memantine has the safest side-effect profile and has long been approved in Alzheimer's disease. The review covers memantine studies in post-herpetic neuralgia, diabetic pain, postoperative pain, complex regional pain syndrome, chronic phantom limb pain, opioid refractory pain, and fibromyalgia...
August 12, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28801514/bilateral-painful-tic-convulsif
#3
Valentina Fenech, Julian Cassar, Ludvic Zrinzo, Malcolm Vella
'Painful tic convulsif' (PTC) describes the coexistence of hemifacial spasm and trigeminal neuralgia. In this report, we describe a unique presentation of bilateral PTC in a man with bilateral hemifacial spasm and trigeminal neuralgia secondary to neurovascular conflict of all four cranial nerves. Following failed medical and radiofrequency therapy, microvascular decompression of three of the four involved nerves was performed, where the offending vessels were mobilised and Teflon used to prevent conflict recurrence...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28799873/-birdlime-technique-using-tachosil-tissue-sealing-sheet-soaked-with-fibrin-glue-for-sutureless-vessel-transposition-in-microvascular-decompression-operative-technique-and-nuances
#4
Naoki Otani, Terushige Toyooka, Kazuya Fujii, Kosuke Kumagai, Satoru Takeuchi, Arata Tomiyama, Yasuaki Nakao, Takuji Yamamoto, Kojiro Wada, Kentaro Mori
OBJECTIVE Microvascular decompression (MVD) is effective for the treatment of trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia. The transposition technique is the standard procedure to avoid adhesions and granuloma around the decompression site but is more complex and difficult to perform than the interposition technique. The authors describe a simple and safe MVD transposition procedure they call the "birdlime" technique, which uses a tissue glue-coated collagen sponge soaked with fibrin glue, and the results of this technique...
August 11, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28799056/single-dose-botulinum-toxin-type-a-compared-with-repeated-dose-for-treatment-of-trigeminal-neuralgia-a-pilot-study
#5
Haifeng Zhang, Yajun Lian, Nanchang Xie, Chen Chen, Yake Zheng
BACKGROUND: Several RCT studies including ours, seem to prove the role of Botulinum toxin type A (BTX-A) in the treatment of trigeminal neuralgia (TN), but no standardized dosing regimen has been established. In our study, we compare two different methods of administration: single-dose or repeated-dose strategy which was most frequently applied over the years in our centre. METHODS: An open-label trail was conducted. One hundred patients with classic TN symptoms were recruited, and randomly and equally apportioned to single- or repeated-dose group...
August 10, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28794656/neuropathic-pain-responds-better-to-increased-doses-of-pregabalin-an-in-depth-analysis-of-flexible-dose-clinical-trials
#6
Michael Serpell, Mark Latymer, Mary Almas, Marie Ortiz, Bruce Parsons, Rita Prieto
BACKGROUND: Pregabalin is an effective treatment option for many patients with neuropathic pain. Higher doses of pregabalin have been shown to be more effective in improving pain outcomes but, in practice, failing to appropriately increase the dose can leave patients under-treated. METHODS: This was a pooled analysis of 6 flexible-dose clinical trials of pregabalin in patients with neuropathic pain (diabetic peripheral neuropathy, peripheral herpetic neuralgia, posttraumatic pain, or postsurgical pain)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28776544/quantitative-evaluation-of-pain-with-pain-index-extracted-from-electroencephalogram
#7
Jian-Xiong An, Yong Wang, Doris K Cope, John P Williams
BACKGROUND: The current pain assessment methods are strongly subjective and easily affected by outside influences, and there is an urgent need to develop a reliable objective and quantitative pain-monitoring indicator. The aim of this study was to evaluate the feasibility of using Pain index (Pi) to assess pain symptoms in pain patients. METHODS: Subjects were enrolled from patients seeking treatment at Pain Medicine Center of China Medical University Aviation General Hospital from October 2015 to December 2016, such as postherpetic neuralgia, spinal cord injury, femoral head necrosis, lumbar disc herniation, trigeminal neuralgia, complex regional pain syndrome, perineal pain, phantom limb pain, etc...
August 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28772087/selective-percutaneous-controlled-radiofrequency-thermocoagulation-of-the-gasserian-ganglion-to-control-facial-pain-due-to-medication-related-osteonecrosis-of-the-jaw
#8
Ayano Taniguchi, Keita Fukazawa, Toyoshi Hosokawa
BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is an important complication in patients treated with antiresorptive agents such as bisphosphonates and the receptor activator of nuclear factor κB ligand inhibitor (denosumab). Treatment of MRONJ is extremely difficult, which makes it a distressing long-term complication. OBJECTIVES: We report a case of intractable facial pain due to MRONJ that was successfully controlled with selective percutaneous controlled radiofrequency thermocoagulation of the Gasserian ganglion...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28765027/factors-determining-the-outcome-in-trigeminal-neuralgia-treated-with-percutaneous-balloon-compression
#9
Tugrul Cem Unal, Omer Faruk Unal, Orhan Barlas, Kemal Hepgul, Achmet Ali, Aydin Aydoseli, Yavuz Aras, Pulat Akin Sabanci, Altay Sencer, Nail Izgi
INTRODUCTION: To analyze 3-Tesla magnetic resonance imaging (MRI) findings and clinical features of patients with trigeminal neuralgia who underwent percutaneous balloon compression (PBC), and to determine whether these findings had an impact on the prognosis of the disease. METHODS: A retrospective review of patients with trigeminal neuralgia who underwent PBC in Istanbul Faculty of Medicine Neurosurgery Department between January 1(st), 2007, and January 1(st), 2016, was undertaken...
July 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28763886/-application-of-neuroendoscope-combined-with-minimal-access-for-elderly-patients-with-idiopathic-trigeminal-neuralgia-in-enhanced-recovery-after-surgery-of-microvascular-decompression
#10
C F Li, N Wu, H Z Wang, J F Zhang, G Q Wu, L Li
Objective: To explore the value of neuroendoscope and minimal-access in enhanced recovery after surgery of microvascular decompression (MVD) for treatment elderly patients with idiopathic trigeminal neuralgia (ITN). Methods: The clinical data of 62 elderly patients with ITN who undergoing neuroendoscope-assisted minimal-access microvascular decompression were analyzed retrospectively, including operative data and follow-up results. Results: In 62 cases, the effective rate was 96.8%, with 88.7% complete cure and 8...
July 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28761370/phenytoin-and-carbamazepine-in-trigeminal-neuralgia-marketing-based-versus-evidence-based-treatment
#11
EDITORIAL
Jan M Keppel Hesselink, Michael E Schatman
No abstract text is available yet for this article.
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28757922/earlier-treatment-improves-the-chances-of-complete-relief-from-postherpetic-neuralgia
#12
Dong Hee Kang, Su Young Kim, Hyuck Goo Kim, Jung Hyun Park, Tae Kyun Kim, Kyung Hoon Kim
BACKGROUND: As herpes zoster progresses via postherpetic neuralgia (PHN) to well-established PHN, it presents its recalcitrant nature to the treatment. At this point, the well-established PHN is fixed as a non-treatable, but manageable chronic painful neuropathic disorder. This study evaluated the incidence of complete relief from PHN according to PHN duration at their first visit, and the other factors influencing it. METHODS: A retrospective chart review was performed on patients with PHN at a university-based pain clinic over 7 years...
July 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28757915/diagnosis-of-occipital-neuralgia-due-to-upper-cervical-chordoma
#13
EDITORIAL
Young Bok Lee
No abstract text is available yet for this article.
July 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28754638/microvascular-decompression-for-trigeminal-neuralgia-using-a-novel-fenestrated-clip-and-tentorial-flap-technique
#14
Lain Hermes Gonzalez-Quarante, Fernando Ruiz-Juretschke, Vijay Agarwal, Roberto Garcia-Leal
BACKGROUND: Microvascular decompression (MVD) for neurovascular compression syndromes such as trigeminal neuralgia and hemifacial spasm has been traditionally described as an interposing technique using Teflon. Some alternative interposing materials have been proposed. Additionally, transposing techniques have been increasingly reported in recent years, as an alternative that may have a lower recurrence rate and fewer complications. OBJECTIVE: To describe our experience utilizing a technique consisting of transposition of the superior cerebellar artery using a fenestrated clip and a tentorial flap in patients with trigeminal neuralgia...
July 25, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28752360/anatomical-characteristics-of-greater-palatine-foramen-a-novel-point-of-view
#15
Daniele Gibelli, Alessia Borlando, Claudia Dolci, Valentina Pucciarelli, Cristina Cattaneo, Chiarella Sforza
PURPOSE: Anatomy of greater palatine foramen is important for maxillary nerve blocks, haemostatic procedures, and the treatment of neuralgia; although metrical data are available about its collocation, still several aspects need to be explored, such as the influence of the cranium size. METHODS: The position of greater palatine foramen was assessed on 100 skulls through six measurements (distances from intermaxillary suture, posterior palatal border, posterior nasal spine, and incisive foramen; palatal length; relative position on palatal length) and two angles (angles at incisive foramen and greater palatine foramen)...
July 27, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28749391/variations-in-herpes-zoster-manifestation
#16
REVIEW
Uwe Wollina
Herpes zoster (HZ) is a neurocutaneous disorder due to endogenous reactivation of the varicella-zoster virus (VZV). The typical clinical manifestation is an acute segmental eruption of herpetiform umbilicated vesicles associated with malaise, pain, dysaesthesia, allodynia and probably fever. This review focuses on other possible clinical manifestations of the disease to sensitize physicians not to overlook HZ since only an early antiviral treatment can reduce the risk of post-zosteric neuralgia.
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28748271/the-emerging-role-of-gamma-knife-radiosurgery-in-the-management-of-glossopharyngeal-neuralgia
#17
REVIEW
Alfio Spina, Nicola Boari, Filippo Gagliardi, Michele Bailo, Carlotta Morselli, Sandro Iannaccone, Pietro Mortini
Glossopharyngeal neuralgia (GPN) represents a rare craniofacial disorder accounting for about 1% of all craniofacial pain syndromes. GPN shares several pathophysiologic and clinical features with the more common trigeminal neuralgia. Medical therapy and microvascular decompression, in case of vascular nerve compression, represented the mainstay of GPN management. Other ablative therapies have been reported to date; however, few data are available because of the rarity of this pain syndrome. Among the ablative procedures, gamma knife radiosurgery (GKRS) has been recently introduced in the management of GPN with good pain control and low complication rates...
July 26, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28739475/posterior-osteosynthesis-with-monoaxial-lateral-mass-screw-rod-system-for-unstable-c1-burst-fractures
#18
Yin-Shun Zhang, Jian-Xiang Zhang, Qing-Guo Yang, Wei Li, Hui Tao, Cai-Liang Shen
BACKGROUND CONTEXT: Surgical treatment for unstable atlas fractures has evolved in recent decades from C1-C2 or C0-C2 fusion to motion-preservation techniques of open reduction and internal fixation (ORIF). However, regardless of transoral or posterior approach, the reduction is still not satisfactory. PURPOSE: The article describes and evaluates a new technique for treating the unstable atlas fractures by using a monoaxial screw-rod system. STUDY DESIGN: This is a retrospective study PATIENT SAMPLE: The sample includes adult patients with unstable C1 fractures treated with a posterior monoaxial screw-rod system...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28738758/laparoscopic-treated-neuralgia-after-inguinal-hernia-repair-case-report-and-literature-review
#19
M Engelen, K Dilen, E Baten
BACKGROUND: Neuralgia after inguinal hernia repair is a known but potential invalidating complication with a reported incidence of 10-12%. Diagnosis and treatment can be challenging. Based on a case report and literature review, disease aspects and treatment options including laparoscopic (triple) neurectomy are discussed. METHODS: A case of laparoscopic treated neuralgia after hernia inguinalis repair is reported. After an extensive MeSH-term based literature search, 26 articles were included for in-depth analysis and literature review...
July 25, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28735437/prospective-and-retrospective-study-of-videoconference-telemedicine-follow-up-after-elective-neurosurgery-results-of-a-pilot-program
#20
Melissa Reider-Demer, Pushpa Raja, Neil Martin, Mariel Schwinger, Diana Babayan
Existing literature suggests that use of telemedicine during postoperative appointments can increase access to care and is valued by patients and providers alike. While research examining the clinical equivalency of telemedicine visits for postoperative care has been growing, few studies have reported on telemedicine follow-up after neurosurgery. This study examined if a videoconferencing visit could substitute for an in-person clinic visit for elective neurosurgical cases in the USA. This was a single-center prospective study of patients who underwent elective neurosurgical procedures (aneurysm clipping, resection of cavernous angiomas, resection of arterial venous malformation, microvascular decompression for trigeminal neuralgia and hemifacial spasm, and certain benign brain tumors) and were offered telemedicine follow-up care by an allied health professional during the first 90 days after neurosurgery...
July 22, 2017: Neurosurgical Review
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