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https://www.readbyqxmd.com/read/27921433/-is-glucosis-only-basic-energy-substrate
#1
Luboš Sobotka
At present time glucose is primarily considered as basic energy substrate. Therefore, it is recommended to give amount of glucose which is necessary for oxidation and energy production. As critical illness is connected with so-called insulin resistance, it is recommended to reduce the glucose dose and maintain normal blood glucose. Glucose, however, may not only be the principal energy substrate but also the substrate necessary for many metabolic reactions, which are essential for normal reactivity and survival...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27921367/dietary-patterns-in-liberian-refugees-in-buduburam-ghana
#2
Wilhelmenia L Ross, Daniel F Gallego-Pérez, Anna Lartey, Adam Sandow, Rafael Pérez-Escamilla, Amber Hromi-Fiedler
Previous research suggests that acculturation (i.e., exposure and assimilation to local culture) is associated with changes in dietary patterns among immigrants. This study investigates this association in a refugee population using time in refugee settlement as a proxy for acculturation. A cross-sectional survey was conducted among a systematic sample to (a) identify dietary patterns in Liberian refugees and Ghanaians living in or near a refugee settlement, (b) compare adherence to these dietary patterns between groups, and (c) investigate the association between acculturation and dietary patterns in Liberian refugees...
December 5, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27921336/magnetic-anisotropy-in-pentacoordinate-ni-ii-and-co-ii-complexes-unraveling-electronic-and-geometrical-contributions
#3
Talal Mallah, Benjamin Cahier, Mauro Perfetti, Georges Zakhia, Daoud Naoufal, Fatima El-Khatib, Régis Guillot, Eric Rivière, Roberta Sessoli, Anne-Laure Barra, Nathalie Guihéry
The magnetic properties of the pentacoordinated [MII(Me4cyclam)N3]+ (Me4cyclam = tetramethylcyclam; N3 = azido and M = Ni and Co) complexes were investigated. Magnetization and EPR studies indicate that they possess an easy plane of magnetization with the axial anisotropy parameters D being close to 22 and larger than 30 cm-1 for the Ni and Co derivative, respectively. Ab initio calculations reproduce the experimental values of the zero field splitting parameters and allow determining the orientation of the anisotropy tensor axes with respect to the molecular frame...
December 6, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27921291/evaluation-of-capillary-electrophoresis-for-the-analysis-of-rooibos-and-honeybush-tea-phenolics
#4
William J Arries, Andreas G J Tredoux, Dalene de Beer, Elizabeth Joubert, André de Villiers
Rooibos and honeybush are popular herbal teas produced from the shrubs of Aspalathus linearis and Cyclopia spp., respectively, which are indigenous to South Africa. Both herbal teas are rich in polyphenols and their consumption is associated with several health benefits, partly ascribed to their phenolic constituents. Quantification of phenolics in extracts and teas for quality control and research purposes is generally performed using HPLC, although dedicated and often species-specific methods are required...
December 6, 2016: Electrophoresis
https://www.readbyqxmd.com/read/27921221/safety-and-efficacy-of-natalizumab-in-japanese-patients-with-relapsing-remitting-multiple-sclerosis-open-label-extension-study-of-a-phase-2-trial
#5
Takahiko Saida, Jun-Ichi Kira, Shuji Kishida, Takashi Yamamura, Nobuhisa Ohtsuka, Yan Ling, Shinichi Torii, Nisha Lucas, Geoffrey Kuesters, Deb Steiner, J T Tibung
INTRODUCTION: The efficacy of natalizumab was evaluated in Japanese patients with relapsing-remitting multiple sclerosis (RRMS) in a 24-week, phase 2 bridging study. An open-label, 2-year extension study from this trial was conducted to assess the safety and efficacy of natalizumab treatment in Japanese patients. METHODS: A total of 97 patients (43 previously on placebo; 54 previously on natalizumab) who had completed the bridging study were treated with 300 mg natalizumab every 4 weeks...
December 5, 2016: Neurology and Therapy
https://www.readbyqxmd.com/read/27921101/the-effect-of-common-anticoagulants-in-detection-and-quantification-of-malaria-parasitemia-in-human-red-blood-cells-by-atr-ftir-spectroscopy
#6
Miguela Martin, David Perez-Guaita, Dean W Andrew, Jack S Richards, Bayden R Wood, Philip Heraud
Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR) has the potential to become a new diagnostic tool for malaria and other diseases. For point-of-care testing, the use of ATR-FTIR in malaria diagnosis enables the analysis of blood in the aqueous state, which represents an enormous advantage by minimising the sample preparation by removing the need for cell fixation. Here we report the quantification of malaria parasitemia in human RBCs in their normal physiological aqueous state...
December 6, 2016: Analyst
https://www.readbyqxmd.com/read/27921050/esophagus-related-symptoms-in-first-degree-relatives-of-patients-with-achalasia-is-screening-necessary
#7
Henning R Gockel, Moritz Lesse, Johannes Schumacher, Michaela Müller, Ines Gockel
BACKGROUND: Despite an increasing understanding of the pathophysiology of achalasia, the etiology of this esophageal motility disorder remains largely unknown. However, the occurrence of familial achalasia, its association with well-defined genetic syndromes, the candidate gene approach, and recent presentation of the first systematic genome-wide association study on achalasia suggest the involvement of genetic factors. METHODS: In this study we analyzed the frequency with which symptoms associated with esophageal function (swallowing difficulties, regurgitations, retrosternal cramps/pain, heartburn) occur in first-degree relatives of patients with achalasia to determine if screening is useful and justified against the background of early diagnosis in a genetically predisposed population...
October 2016: Visceral Medicine
https://www.readbyqxmd.com/read/27921018/comparison-of-the-protective-effects-of-erythropoietin-and-melatonin-on-renal-ischemia-reperfusion-injury
#8
Shokofeh Banaei, Nasser Ahmadiasl, Alireza Alihemmati
BACKGROUND: Renal ischemia-reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be the principal components involved in the pathophysiological tissue alterations observed during renal IR. OBJECTIVES: In this study, we compared the effects of melatonin (MEL) and erythropoietin (EPO), both known antioxidant and anti-inflammatory agents, on IR-induced renal injury in rats. MATERIALS AND METHODS: Wistar albino rats were unilaterally nephrectomized and then subjected to 45 minutes of renal pedicle occlusion followed by 24 hours of reperfusion...
July 2016: Trauma Monthly
https://www.readbyqxmd.com/read/27920763/microbial-activity-response-to-solar-radiation-across-contrasting-environmental-conditions-in-salar-de-huasco-northern-chilean-altiplano
#9
Klaudia L Hernández, Beatriz Yannicelli, Lasse M Olsen, Cristina Dorador, Eduardo J Menschel, Verónica Molina, Francisco Remonsellez, Martha B Hengst, Wade H Jeffrey
In high altitude environments, extreme levels of solar radiation and important differences of ionic concentrations over narrow spatial scales may modulate microbial activity. In Salar de Huasco, a high-altitude wetland in the Andean mountains, the high diversity of microbial communities has been characterized and associated with strong environmental variability. Communities that differed in light history and environmental conditions, such as nutrient concentrations and salinity from different spatial locations, were assessed for bacterial secondary production (BSP, (3)H-leucine incorporation) response from short-term exposures to solar radiation...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27920597/a-multivariate-study-of-differentiating-characters-between-three-european-species-of-the-genus-lasiochernes-beier-1932-pseudoscorpiones-chernetidae
#10
Jana Christophoryová, Katarína Krajčovičová, Hans Henderickx, Stanislav Španiel
Morphological variation in three rarely collected European species of the genus Lasiochernes Beier, 1932 is thoroughly examined in the present study. Detailed descriptions of previously ignored morphological characters of Lasiochernes cretonatus Henderickx, 1998, Lasiochernes jonicus (Beier, 1929) and Lasiochernes pilosus (Ellingsen, 1910) are presented. The female of Lasiochernes cretonatus and the nymphs of Lasiochernes pilosus are described for the first time. Multivariate morphometric techniques (principal coordinate analysis and discriminant analyses) were employed to confirm morphological differentiation of the three Lasiochernes species and to identify the most reliable characters for their separation...
2016: ZooKeys
https://www.readbyqxmd.com/read/27919857/hepatic-perivascular-epithelioid-cell-tumor-in-three-patients
#11
Bao-Bin Hao, Jian-Hua Rao, Ye Fan, Chuang-Yong Zhang, Xin-Zheng Dai, Xiao Li, Yan Leng, Feng Zhang
Perivascular epithelioid cell tumor (PEComa) is a rare, soft tissue tumor that can occur in various locations. The present report included three patients (one male and two females; age range, 25-51 years) with hepatic PEComas. The collected data included the clinical manifestations, diagnosis, management, treatment, and prognosis. Since it is difficult to diagnose hepatic PEComas by imaging, the patients were diagnosed by tumor tissue examination such as immunohistochemistry, which was positive for HMB-45, Melan-A, and SMA on all slides...
December 2016: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/27919559/effects-of-flow-regime-on-benthic-algae-and-macroinvertebrates-a-comparison-between-regulated-and-unregulated-rivers
#12
Susanne C Schneider, Zlatko Petrin
Natural fluctuations in flow are important for maintaining the ecological integrity of riverine ecosystems. However, the flow regime of many rivers has been modified. We assessed the impact of water chemistry, habitat and streamflow characteristics on macroinvertebrates and benthic algae, comparing 20 regulated with 20 unregulated sites. Flow regime, calculated from daily averaged discharge over the five years preceding sampling, was generally more stable at regulated sites, with higher relative discharges in winter, lower relative discharges in spring and smaller differences between upper and lower percentiles...
December 2, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27919551/defining-the-core-microbiome-in-corals-microbial-soup
#13
REVIEW
Alejandra Hernandez-Agreda, Ruth D Gates, Tracy D Ainsworth
Corals are considered one of the most complex microbial biospheres studied to date, hosting thousands of bacterial phylotypes in species-specific associations. There are, however, substantial knowledge gaps and challenges in understanding the functional significance of bacterial communities and bacterial symbioses of corals. The ubiquitous nature of some bacterial interactions has only recently been investigated and an accurate differentiation between the healthy (symbiotic) and unhealthy (dysbiotic) microbial state has not yet been determined...
December 2, 2016: Trends in Microbiology
https://www.readbyqxmd.com/read/27919489/cognitive-event-related-potentials-in-multiple-sclerosis-correlation-with-mri-and-neuropsychological-findings
#14
Vasilios K Kimiskidis, Vasileios Papaliagkas, Kyriaki Sotirakoglou, Zoi K Kouvatsou, Victoria K Kapina, Efrosini Papadaki, Vaia Tsimourtou, Elvira Masoura, Dimitrios A Kazis, Sotirios Papayiannopoulos, Triantafyllos Geroukis, Sevasti Bostanjopoulou
BACKGROUND: Cognitive event-related potentials (ERPs) have been previously correlated with T2 lesion load (Τ2LL) in patients with multiple sclerosis (MS). It is currently unknown, however, whether ERPs also correlate with brain atrophy or the presence of T1 hypointense lesions ("black holes") which reflect tissue destruction and axonal loss. The primary aim of the current study is to explore the effect of neuroradiological parameters such as brain atrophy, T1 and T2 lesion load on auditory ERPs in MS patients...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27919385/usability-problems-do-not-heal-by-themselves-national-survey-on-physicians-experiences-with-ehrs-in-finland
#15
Johanna Kaipio, Tinja Lääveri, Hannele Hyppönen, Suvi Vainiomäki, Jarmo Reponen, Andre Kushniruk, Elizabeth Borycki, Jukka Vänskä
PURPOSE: Survey studies of health information systems use tend to focus on availability of functionalities, adoption and intensity of use. Usability surveys have not been systematically conducted by any healthcare professional groups on a national scale on a repeated basis. This paper presents results from two cross-sectional surveys of physicians' experiences with the usability of currently used EHR systems in Finland. The research questions were: To what extent has the overall situation improved between 2010 and 2014? What differences are there between healthcare sectors? METHODS: In the spring of 2014, a survey was conducted in Finland using a questionnaire that measures usability and respondents' user experiences with electronic health record (EHR) systems...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27919275/rayyan-a-web-and-mobile-app-for-systematic-reviews
#16
Mourad Ouzzani, Hossam Hammady, Zbys Fedorowicz, Ahmed Elmagarmid
BACKGROUND: Synthesis of multiple randomized controlled trials (RCTs) in a systematic review can summarize the effects of individual outcomes and provide numerical answers about the effectiveness of interventions. Filtering of searches is time consuming, and no single method fulfills the principal requirements of speed with accuracy. Automation of systematic reviews is driven by a necessity to expedite the availability of current best evidence for policy and clinical decision-making. We developed Rayyan ( http://rayyan...
December 5, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27919146/-cancer-mortality-of-residents-near-a-steel-factory-in-udine-friuli-venezia-giulia-region-northern-italy
#17
Luigi Castriotta, Anica Casetta, Fabio Barbone
OBJECTIVES: to evaluate the association between distance of residence from a steel factory, a point source of air pollution within an industrial area in Udine (Friuli Venezia Giulia Region, Northern Italy), and cancer mortality. DESIGN: retrospective study. To evaluate the association between mortality rates and distance from the source, a Stone test analysis for all cases occurred in the entire area was conducted. The significance level was determined using Monte Carlo simulations...
November 2016: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/27919059/role-of-maternal-occupational-physical-activity-and-psychosocial-stressors-on-adverse-birth-outcomes
#18
Laura J Lee, Elaine Symanski, Philip J Lupo, Sarah C Tinker, Hilda Razzaghi, Wenyaw Chan, Adrienne T Hoyt, Mark A Canfield
OBJECTIVES: We examined the association of an array of estimated maternal occupational physical activities and psychosocial stressors during pregnancy with odds for preterm birth (PTB) and small-for-gestational age (SGA). METHODS: Data for infants born without major birth defects delivered from 1997 to 2009 whose mothers reported working at least 1 month during pregnancy were obtained from the National Birth Defects Prevention Study. We linked occupational codes to the US Department of Labor's Occupational Information Network, which provides estimates of exposure for multiple domains of physical activity and psychosocial stressors by occupational categories...
October 6, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27918957/genetic-variability-in-the-system-of-natriuretic-b-peptide-and-principal-toxicological-parameters-in-workers-exposed-to-lead
#19
Marta Jurdziak, Paweł Gać, Rafał Poręba, Marzena Gonerska, Anna Jonkisz, Małgorzata Gromek, Małgorzata Poręba, Anna Szymańska-Chabowska, Grzegorz Mazur, Małgorzata Sobieszczańska
The study was aimed at evaluating the influence of selected polymorphisms of natriuretic peptide B precursor (NPPB) and natriuretic peptide receptor C (NPR3) genes on blood lead concentration (Pb-B) and blood zinc protoporphyrin concentration (ZnPP) in persons occupationally exposed to lead. Investigations were conducted on 360 persons (mean age: 44.49±9.62years), workers exposed to lead compounds. The analysis examined four polymorphisms of BNP gene, i.e.,: rs198388, rs198389, rs632793, and rs6676300; as well as one polymorphism of receptor C for natriuretic peptides, i...
November 21, 2016: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/27918944/groundwater-nitrate-pollution-and-human-health-risk-assessment-by-using-hhra-model-in-an-agricultural-area-ne-china
#20
Yuanzheng Zhai, Xiaobing Zhao, Yanguo Teng, Xiao Li, Junjun Zhang, Jin Wu, Rui Zuo
In order to learn the pollution circumstance of groundwater nitrate detailedly in Songnen Plain of Northeast China and estimate its potential risk to human health of local residents, a total of 389 groundwater samples were collected in 2014 and studied from residential areas and public water supply wells in 11 cities and counties in southeastern of Songnen Plain. The analysis results showed that the spatial distributions of main chemical components in groundwater had great variations with statistical concentrations in the order of TDS> HCO3> Ca> NO3> Cl> Na> SO4> Mg> K> NH4> NO2...
December 1, 2016: Ecotoxicology and Environmental Safety
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