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https://www.readbyqxmd.com/read/28931202/different-sized-incisions-for-phacoemulsification-in-age-related-cataract
#1
REVIEW
Chongfei Jin, Xinyi Chen, Andrew Law, Yunhee Kang, Xue Wang, Wen Xu, Ke Yao
BACKGROUND: Age-related cataract is the principal cause of blindness and visual impairment in the world. Phacoemulsification is the main surgical procedure used to treat cataract. The comparative effectiveness and safety of different-sized incisions for phacoemulsification has not been determined. OBJECTIVES: The aim of this systematic review was to assess the effectiveness and safety of smaller versus larger incisions for phacoemulsification in age-related cataract...
September 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28931039/abnormalities-in-substance-p-neurokinin-1-receptor-binding-in-key-brainstem-nuclei-in-sudden-infant-death-syndrome-related-to-prematurity-and-sex
#2
Fiona M Bright, Robert Vink, Roger W Byard, Jhodie R Duncan, Henry F Krous, David S Paterson
Sudden infant death syndrome (SIDS) involves failure of arousal to potentially life threatening events, including hypoxia, during sleep. While neuronal dysfunction and abnormalities in neurotransmitter systems within the medulla oblongata have been implicated, the specific pathways associated with autonomic and cardiorespiratory failure are unknown. The neuropeptide substance P (SP) and its tachykinin neurokinin-1 receptor (NK1R) have been shown to play an integral role in the modulation of homeostatic function in the medulla, including regulation of respiratory rhythm generation, integration of cardiovascular control, and modulation of the baroreceptor reflex and mediation of the chemoreceptor reflex in response to hypoxia...
2017: PloS One
https://www.readbyqxmd.com/read/28931009/ndfip-allows-nedd4-nedd4l-induced-aqp2-ubiquitination-and-degradation
#3
Christiane Trimpert, Daniel Wesche, Theun de Groot, Martha M Pimentel Rodriguez, Victoria Wong, Dennis T M van den Berg, Lydie Cheval, Carolina A Ariza, Alain Doucet, Igor Stagljar, Peter M T Deen
Regulation of our water homeostasis is fine-tuned by dynamic translocation of Aquaporin-2 (AQP2)-bearing vesicles to and from the plasma membrane of renal principal cells. Whereas binding of vasopressin to its type-2 receptor initiates a cAMP-protein kinase A cascade and AQP2 translocation to the apical membrane, this is counteracted by protein kinase C-activating hormones, resulting in ubiquitination-dependent internalization of AQP2. The proteins targeting AQP2 for ubiquitin-mediated degradation are unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28930872/improving-vertical-jump-profiles-through-prescribed-movement-plans
#4
John K Mayberry, Bryce Patterson, Phil Wagner
Developing practical, reliable, and valid methods for monitoring athlete wellness and injury risk is an important goal for trainers, athletes, and coaches. Previous studies have shown that the countermovement vertical jump test (CMJ) is both a reliable and valid metric for evaluating an athlete's condition. This study examines the effectiveness of prescribed workouts on improving quality of movement during CMJ. The dataset consists of 2425 pairs of CMJ scans for high school, college, and professional athletes training at a privately owned facility...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930763/a-new-community-health-center-academic-medicine-partnership-for-medicaid-cost-control-powered-by-the-mega-teaching-health-center
#5
Richard E Rieselbach, Ted Epperly, Aaron Friedman, David Keahey, Eleanor McConnell, Karen Nichols, Greg Nycz, Jeanette Roberts, Kenneth Schmader, Peter Shin, Derri Shtasel
Community health centers (CHCs), a principal source of primary care for over 24 million patients, provide high-quality affordable care for medically underserved and lower-income populations in urban and rural communities. The authors propose that CHCs can assume an important role in the quest for health care reform by serving substantially more Medicaid patients. Major expansion of CHCs, powered by mega teaching health centers (THCs) in partnership with regional academic medical centers (AMCs) or teaching hospitals, could increase Medicaid beneficiaries' access to cost-effective care...
September 14, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28930696/impact-of-a-newly-formed-periglacial-environment-and-other-factors-on-fresh-water-chemistry-at-the-western-shore-of-admiralty-bay-in-the-summer-of-2016-king-george-island-maritime-antarctica
#6
Małgorzata Szopińska, Danuta Szumińska, Robert Józef Bialik, Stanisław Chmiel, Joanna Plenzler, Żaneta Polkowska
This study provides a comprehensive analysis of the inorganic chemistry of flowing water at the western shore of Admiralty Bay. In the water samples, ions, and major and trace metals (and B) were detected and quantified. Additionally, the parameters of pH, specific electrolytic conductivity (SEC25) and total organic carbon (TOC) were determined. Moreover, multivariate data set was created and Principal Component Analysis (PCA) was performed. Generally, the water has low total content of the measured mineral constituents <100mgL(-1)...
September 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28930554/diet-microparticles-and-atherothrombosis
#7
Lina Badimon, Rosa Suades, Javier Crespo, Teresa Padro, Gemma Chiva-Blanch
Cardiovascular disease is the main cause of death worldwide, and is principally caused by atherosclerosis, with subsequent thrombus formation, eventually provoking an acute myocardial infarction or a stroke. The formation and progression of the atherosclerotic plaques responds to multiple factors including certain diets. Intensive research has elucidated the role of diet in cardiovascular disease and has led to public health policies focusing on educating the population on the role of nutrition in cardiovascular health...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28930373/venous-thromboembolism-in-obese-pregnant-women-approach-to-diagnosis-and-management
#8
Ann Kinga Malinowski, Dorota Bomba-Opoń, Jacqueline Parrish, Urszula Sarzyńska, Dan Farine
Venous thromboembolism (VTE) remains among the leading causes of maternal mortality in the developed world, presenting variably as deep vein thrombosis (DVT), pulmonary embolism (PE) or cerebral vein thrombosis (CVT), among others. Obesity in particular has been recognized as the principal contributing factor to the risk of VTE in pregnancy and with the global increase in the rates of obesity affecting reproductive age women, heightened awareness of the risk and consequences of VTE in this population are vital...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28930269/chemical-composition-antifungal-and-antioxidant-activities-of-hedyosmum-brasiliense-mart-ex-miq-chloranthaceae-essential-oils
#9
Cynthia Murakami, Inês Cordeiro, Marcus Tullius Scotti, Paulo Roberto H Moreno, Maria Cláudia M Young
Background: Hedyosmum brasiliense Mart. ex Miq. (Chloranthaceae) is a dioecious shrub popularly used in Brazil to treat foot fungi and rheumatism. This work investigated the chemical composition, antifungal, and antioxidant activities of flowers and leaves of H. brasiliense essential oils; Methods: H. brasiliense male and female flowers and leaves were collected at Ilha do Cardoso (São Paulo) and the essential oils were extracted by hydrodistillation and analyzed by GC/MS and their similarity compared by Principal Component Analysis...
July 17, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929876/le-leadership-en-sant%C3%A3-et-la-philosophie-appliqu%C3%A3-e-une-ressource-essentielle
#10
Elizabeth Fistein, David Cruise Malloy
En qualité de professionnels de la santé, nous sommes déterminés à assurer l'exploitation efficiente et efficace de nos établissements. Les outils dont nous disposons sont les structures bureaucratiques, les règles, les règlements, les politiques et, bien sûr, les mesures. Il n'y a rien de foncièrement pernicieux à avoir des établissements efficients, efficaces et mesurés, mais nous soutenons que l'humanité et l'authenticité manquent cruellement dans cet environnement, au prix d'un travail significatif...
July 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28929692/-metabolomics-of-bovine-serum-albumin-induced-allergic-reactions-based-on-uplc-q-tof-ms
#11
Yuan-Yuan Gu, Dan-Dan Zhang, Cheng Feng, Yu Wang, Da-Zhong Chen, Yan-Hong Wang
The metabonomic techniques were used to study the changes in endogenous metabolites between urines of rats in normal physiological conditions and bovine serum albumin induced allergic reactions, identify potential biomarkers associated with allergic reactions, and then analyze the metabolic pathways and the metabolic mechanisms of allergic reactions. The bovine serum albumin-induced allergic reactions in rats were adopted as a model to detect histamine and tryptase in rat serum and observe the issue morphology of lungs and trachea in rats...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929689/-comparatively-evaluating-effect-contribution-of-promoting-blood-circulation-of-herb-pairs-containing-angelicae-sinensis-radix-on-xin-sheng-hua-granule-by-withdrawal-analysis
#12
Han-Qing Pang, Jun Wang, Yu-Ping Tang, Liang Wu, Hui-Qin Xu, Yi Jin, Zhen-Hua Zhu, Sheng-Liang Huang, Da-Zheng Sun, Jin-Ao Duan
Xin-Sheng-Hua granule (XSHG) is a popular remedy commonly used in clinic for the treatment of lochiostasis after delivery. To comparatively investigate the roles of herb pairs containing Angelicae Sinensis Radix (Danggui) upon the formula by evaluating the blood coagulation and hemorheology function in acute blood stasis rats, acute blood stasis rat model was established by ice water bath and subcutaneous injection of adrenaline. And the blood stasis mice were administrated intragastrically with different samples of the formula minus herb pairs containing Danggui and the whole formula (XSHG, SHD, DY, DC, DT, DH, DJ and DZ)...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929683/-comparison-of-alkaloids-in-roots-of-cultivated-and-wild-sophora-flavsecens
#13
Li Yao, Hong Yi, Hui-Min Gao, Hui-Wen Ma, Ji-Yuan Zhang, Lian-Chao Tian, Xiao-Qian Liu, Zhi-Min Wang
To compare the contents of alkaloids in theroots of cultivated and the wild Sophora flavsecens, 22 cultivated and 17 wild samples were collected. HPLC method was employed to simultaneously determine the contents of six alkaloids (oxymatrine, oxysophocarpine, sophoridine, N-methylcytisine, matrine, and sophocarpine). Independent t-test, hierarchical clustering analysis(HCA)and principal components analysis (PCA) were applied to analyze and evaluate the cultivated and the wild S.flavsecens. With a great wide range of the inter-group, the t-test results showed that the contents difference of N-methylcytisine, matrine, and sophocarpine were statistical significance(matrineandsophocarpine P<0...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929642/facilitating-in-vivo-tumor-localization-by-principal-component-analysis-based-on-dynamic-fluorescence-molecular-imaging
#14
Yang Gao, Maomao Chen, Junyu Wu, Yuan Zhou, Chuangjian Cai, Daliang Wang, Jianwen Luo
Fluorescence molecular imaging has been used to target tumors in mice with xenograft tumors. However, tumor imaging is largely distorted by the aggregation of fluorescent probes in the liver. A principal component analysis (PCA)-based strategy was applied on the in vivo dynamic fluorescence imaging results of three mice with xenograft tumors to facilitate tumor imaging, with the help of a tumor-specific fluorescent probe. Tumor-relevant features were extracted from the original images by PCA and represented by the principal component (PC) maps...
September 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28929641/patients-choice-between-public-and-private-hospital-emergency-departments-a-cross-sectional-survey
#15
Jun He, Xiang-Yu Hou, Ghasem Sam Toloo, Gerry FitzGerald
OBJECTIVE: The aim of this study was to understand what factors influence patients' choice between public and private hospital ED and the relative weight of those factors among adult patients with private health insurance in Australia. METHODS: A survey of 280 patients was conducted in four public and private hospitals' EDs in Brisbane between May and August 2015. The survey included information about respondent's demographics, nature of illness, decision-making, attitudes and choice...
September 19, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28929566/protracted-dendritic-growth-in-the-typically-developing-human-amygdala-and-increased-spine-density-in-young-asd-brains
#16
R K Weir, M D Bauman, B Jacobs, C M Schumann
The amygdala is a medial temporal lobe structure implicated in social and emotional regulation. In typical development (TD), the amygdala continues to increase volumetrically throughout childhood and into adulthood, while other brain structures are stable or decreasing in volume. In autism spectrum disorder (ASD), the amygdala undergoes rapid early growth, making it volumetrically larger in children with ASD compared to TD children. Here we explore: 1) if dendritic arborization in the amygdala follows the pattern of protracted growth in TD and early overgrowth in ASD and 2), if spine density in the amygdala in ASD cases differs from TD from youth to adulthood...
September 20, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28929382/serial-assessment-of-left-ventricular-morphology-and-function-in-a-rodent-model-of-ischemic-cardiomyopathy
#17
Vesselina Ferferieva, Nicholas D'Elia, Brecht Heyde, Petr Otahal, Frank Rademakers, Jan D'hooge
Left ventricular remodelling (LVr) occurs post myocardial infarction (MI), predisposing people to heart failure (HF). LV mechanics and morphology are important in this process. We hence sort to characterize LV mechanics and geometry in a post-MI rodent model. Thirty-two male Sprague-Dawley rats (150-200 g) sustained MI (n = 24) or sham (Sham; n = 8) surgery. In another six sham rats invasive blood pressure measurements were performed. Ultrasound imaging was done at baseline, and 1, 3, 7, 14, 30 and 60 days following surgery, and LV mechanics and morphology assessed...
September 19, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28929184/metabolic-changes-in-primary-secondary-and-lipid-metabolism-in-tobacco-leaf-in-response-to-topping
#18
Jieyu Zhao, Lili Li, Yanni Zhao, Chunxia Zhao, Xia Chen, Pingping Liu, Huina Zhou, Junjie Zhang, Chunxiu Hu, Aiguo Chen, Guanshan Liu, Xiaojun Peng, Xin Lu, Guowang Xu
As an important cultivation practice used for flue-cured tobacco, topping affects diverse biological processes in the later stages of development and growth. Some studies have focused on using tobacco genes to reflect the physiological changes caused by topping. However, the complex metabolic shifts in the leaf resulting from topping have not yet been investigated in detail. In this study, a comprehensive metabolic profile of primary, secondary, and lipid metabolism in flue-cured tobacco leaf was generated with use of a multiple platform consisting of gas chromatography-mass spectrometry, capillary electrophoresis-mass spectrometry, and liquid chromatography-mass spectrometry/ultraviolet spectroscopy...
September 19, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28928881/low-expression-of-cdk10-correlates-with-adverse-prognosis-in-gastric-carcinoma
#19
Bai-Wei Zhao, Shi Chen, Yuan-Fang Li, Jun Xiang, Zhi-Wei Zhou, Jun-Sheng Peng, Ying-Bo Chen
Background: Cyclin-dependent kinase (CDK) 10, is reported to play an essential role in the progression from the G2 to M phase of the cell cycle. Recently, reduced expression of CDK10 has been observed in several cancerous human tissue, suggesting that CDK10 is a tumor suppressor gene. However, data on its expression pattern and clinical relevance in gastric cancer are not sufficient. Therefore, this study aims to investigate CDK10 expression and its prognostic significance in primary gastric adenocarcinoma...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28928746/ccl5-glutamate-cross-talk-in-astrocyte-neuron-communication-in-multiple-sclerosis
#20
REVIEW
Anna Pittaluga
The immune system (IS) and the central nervous system (CNS) are functionally coupled, and a large number of endogenous molecules (i.e., the chemokines for the IS and the classic neurotransmitters for the CNS) are shared in common between the two systems. These interactions are key elements for the elucidation of the pathogenesis of central inflammatory diseases. In recent years, evidence has been provided supporting the role of chemokines as modulators of central neurotransmission. It is the case of the chemokines CCL2 and CXCL12 that control pre- and/or post-synaptically the chemical transmission...
2017: Frontiers in Immunology
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