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https://www.readbyqxmd.com/read/29223651/effects-of-the-rigid-gas-permeable-contact-lense-use-on-tear-and-ocular-surface-among-keratoconus-patients
#1
Cansu Yuksel Elgin, Guzin Iskeleli, Ovgu Aydin
PURPOSE: To investigate changes in tear and ocular surface of patients with keratoconus using rigid gas permeable contact lenses (RGPCL) and compare them against keratoconus patients who were not using lenses as well as a control group of healthy subjects. METHODS: 24 keratoconus patients using RGPCL (Group 1) 22 patients who were not using lenses (Group 3) and 21 healthy subjects (Group 3) were included in the study. Subjective complaints about the subjects' eyes have been investigated using the ocular-surface disease index (OSDI)...
December 6, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29221709/the-use-of-contact-lenses-among-university-students-in-chengdu-knowledge-and-practice-of-contact-lens-wearers
#2
Qiurong Zhu, Bi Yang, Nan Deng, Yifan Li, Tingwei Wang, Huang Qi, Longqian Liu
PURPOSE: To assess the prevalence and general knowledge of contact lens wearers among college students in Chengdu, a metroplolitan of Chinaand find out the routine habits of use and hygienic conditions when wearing contact lenses. METHOD: The questionnaire was distributed to 1,600 ametropic participants who were from 8 different universities. Data about demographics, general contact lens handling habits, personal attitudes, hygiene behaviors and eye health conditions were collected...
December 5, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29221708/daily-versus-monthly-disposable-contact-lens-which-is-better-for-ocular-surface-physiology-and-comfort
#3
Kishor Sapkota, Sandra Franco, Madalena Lira
PURPOSE: To investigate the effect of soft contact lenses (SCL) wearing modality and lens materials on the changes in conjunctival bulbar and limbal redness and conjunctival and corneal staining after two months of SCL wear. Comfort level was also analyzed. METHODS: In this longitudinal clinical trial, forty-seven neophyte myopic subjects were fitted with a monthly disposable lens (lotrafilcon-B or comfilcon-A or balafilcon-A) in one eye and a daily disposable lens (nelfilcon-A or stenofilcon-A or nesofilcon-A) in the other eye, randomly selected...
December 5, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29217475/in-vitro-drug-release-and-in-vivo-safety-of-vitamin-e-and-cysteamine-loaded-contact-lenses
#4
Phillip Dixon, Richard C Fentzke, Arnab Bhattacharya, Aditya Konar, Sarbani Hazra, Anuj Chauhan
Cystinosis is an orphan disease caused by a genetic mutation that leads to deposition of cystine crystals in many organs including cornea. Ophthalmic manifestation of the disease can be treated with hourly instillation of cysteamine eye drops. The hourly eye drop instillation is tedious to the patients leading to poor compliance and additionally, significant degradation of the drug occurs within one week of opening the bottle, which further complicates this delivery approach. This paper focuses on designing a contact lens to treat the disease with improved efficacy compared to eye drops, and also exploring safety of the drug eluding contact lens in an animal model...
December 4, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29217454/patient-related-barriers-to-rigid-gas-permeable-rgp-lens-wear-among-keratoconus-patients-in-jordan
#5
May M Bakkar, Mera F Haddad, Mohammad Al Qadire
PURPOSE: To assess potential patient-related barriers to rigid gas permeable (RGP) lens wear for vision rehabilitation in a sample of keratoconus (KC) patients in Jordan. METHODS: Barriers for RGP contact lens wear among KC patients were discussed and specified by a focus group which consisted of five optometrists who are involved in contact lens practice. The focus group addressed potential barriers for RGP lens wear from the patient's perspective. The identified barriers were then used to design the final questionnaire used in the study...
December 4, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29217022/focal-limbal-stem-cell-deficiency-associated-with-soft-contact-lens-wear
#6
Karolien Termote, Steven Schendel, Gregory Moloney, Simon P Holland, Alex P Lange
OBJECTIVE: The aim of this study is to summarize the clinical characteristics of patients with contact lens-associated focal limbal stem cell deficiency (FLSCD) from a tertiary corneal referral centre. DESIGN: Retrospective, observational case series in a tertiary care centre. METHODS: Patients with contact lens-associated FLCSD were identified in our database. Clinical data were retrieved by chart review. A questionnaire asking for contact lens brand, type, cleaning solution, and duration of contact lens wear was sent to the patients with telephone follow-up...
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29216189/new-intraocular-pressure-measurement-method-using-reflected-pneumatic-pressure-from-cornea-deformed-by-air-puff-of-ring-type-nozzle
#7
Hyung Jin Kim, Yeong Ho Seo, Byeong Hee Kim
In this study, a non-contact type intraocular pressure (IOP) measuring system using reflected pneumatic pressure is proposed to overcome the disadvantages of existing measurement systems. A ring-type nozzle, a key component in the proposed system, is designed via computational fluid analysis. It predicts the reflected pneumatic pressure based on the nozzle exit angle and inner and outer diameters of the nozzle, which are 30°, 7 mm, and 9 mm, respectively. Performance evaluation is conducted using artificial eyes fabricated using polydimethylsiloxane with the specifications of human eyes...
2017: PloS One
https://www.readbyqxmd.com/read/29209437/retinal-venous-pressure-measurements-in-patients-with-flammer-syndrome-and-metabolic-syndrome
#8
Dominique Mustur, Zakieh Vahedian, Jerome Bovet, Maneli Mozaffarieh
Background: The purpose of this research is to analyze retinal venous pressure (RVP) of both eyes of patients who visited a Swiss ophthalmic practice and compare values among the following groups of patients with primary open-angle glaucoma (POAG), Flammer syndrome (FS), and metabolic syndrome (MetS). Methods: RVP was measured in both eyes of all patients who visited a Swiss ophthalmic practice during March 2016 till November 2016, and the results were analyzed retrospectively...
December 2017: EPMA Journal
https://www.readbyqxmd.com/read/29209259/reinforcement-learning-in-autism-spectrum-disorder
#9
REVIEW
Manuela Schuetze, Christiane S Rohr, Deborah Dewey, Adam McCrimmon, Signe Bray
Early behavioral interventions are recognized as integral to standard care in autism spectrum disorder (ASD), and often focus on reinforcing desired behaviors (e.g., eye contact) and reducing the presence of atypical behaviors (e.g., echoing others' phrases). However, efficacy of these programs is mixed. Reinforcement learning relies on neurocircuitry that has been reported to be atypical in ASD: prefrontal-sub-cortical circuits, amygdala, brainstem, and cerebellum. Thus, early behavioral interventions rely on neurocircuitry that may function atypically in at least a subset of individuals with ASD...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29208347/usefulness-of-bandage-contact-lenses-in-the-immediate-postoperative-period-after-uneventful-myopic-lasik
#10
Mar Seguí-Crespo, Javier Parra Picó, Pedro Ruíz Fortes, Alberto Artola Reig, Francisco J Blanes-Mompó, Rafael J Pérez-Cambrodí
PURPOSE: To determine the usefulness of a silicone-hydrogel bandage contact lens (BCL) in the immediate postoperative period after uneventful myopic laser in-situ keratomileusis (LASIK). METHODS: The study design was randomized but not masked and data collection was prospective. This study comprised 51 consecutive myopic eyes intervened by means of the LASIK technique to compensate their refractive error. Patients were randomly assigned to two different groups. The experimental group included 24 eyes of 12 patients that were fitted with a BCL immediately after the flap replacement...
December 2, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29196835/eye-contact-effects-on-social-preference-and-face-recognition-in-normal-ageing-and-in-alzheimer-s-disease
#11
D Lopis, M Baltazar, N Geronikola, V Beaucousin, L Conty
Perceiving a direct gaze (i.e. another individual's gaze directed to the observer leading to eye contact) influences positively a wide range of cognitive processes. In particular, direct gaze perception is known to stimulate memory for other's faces and to increase their likeability. Alzheimer's disease (AD) results in social withdrawal and cognitive decline. However, patients show preserved eye contact behaviours until the middle stage of the disease. The eye contact effects could be preserved in AD and be used to compensate for cognitive and social deficits...
December 1, 2017: Psychological Research
https://www.readbyqxmd.com/read/29195358/novel-single-cell-mega-size-chambers-for-electrochemical-etching-of-panorama-position-sensitive-polycarbonate-ion-image-detectors
#12
Mehdi Sohrabi
A novel development is made here by inventing panorama single-cell mega-size electrochemical etching (MS-ECE) chamber systems for processing panorama position-sensitive mega-size polycarbonate ion image detectors (MS-PCIDs) of potential for many neutron and ion detection applications in particular hydrogen ions or proton tracks and images detected for the first time in polycarbonates in this study. The MS-PCID is simply a large polycarbonate sheet of a desired size. The single-cell MS-ECE invented consists of two large equally sized transparent Plexiglas sheets as chamber walls holding a MS-PCID and the ECE chamber components tightly together...
November 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29194378/chitosan-nanoparticles-as-a-mucoadhesive-drug-delivery-system-for-ocular-administration
#13
Mariana M Silva, Raquel Calado, Joana Marto, Ana Bettencourt, António J Almeida, Lídia M D Gonçalves
Pharmaceutical approaches based on nanotechnologies and the development of eye drops composed of the mucoadhesive polymers chitosan and hyaluronic acid are emerging strategies for the efficient treatment of ocular diseases. These innovative nanoparticulate systems aim to increase drugs' bioavailability at the ocular surface. For the successful development of these systems, the evaluation of mucoahesiveness (the interaction between the ocular delivery system and mucins present on the eye) is of utmost importance...
December 1, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29194205/a-protective-eye-shield-reduces-limbal-strain-and-its-variability-during-simulated-sleep-in-adults-with-glaucoma
#14
Alison Flatau, Francisco Solano, Joan L Jefferys, Christopher Damion, Harry A Quigley
PURPOSE: To determine the effect of wearing a protective eye shield (mask) on limbal strain magnitude and variability in glaucoma eyes when sleeping with 1 side of the face down (FD) against a pillow. METHODS: A prospective, randomized, interventional trial was conducted at the Wilmer Eye Institute with 36 glaucoma patients. A contact lens sensor measured limbal strain (output in equivalent millivolts) during intervals of up to 60 minutes in lateral decubitus, FD, and supine positions...
November 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29191679/intraocular-pressure-measurements-and-corneal-biomechanical-properties-using-a-dynamic-scheimpflug-analyzer-after-several-keratoplasty-techniques-versus-normal-eyes
#15
J Hugo, E Granget, G Ho Wang Yin, M Sampo, L Hoffart
PURPOSE: To evaluate the biomechanical properties of the cornea and their impact on intraocular pressure (IOP) measurement after lamellar keratoplasty, compared to healthy eyes, using a non-contact tonometer with a Scheimpflug camera. METHODS: This study, from 2014 to 2015, included 22 primary DSAEK, 5 DALK, 6 DSAEK after PK, and 50 control eyes. Using a non-contact tonometer with a high-speed Scheimpflug camera (CORVIS ST, Oculus Optikgeräte GmbH, Wetzlar, Germany), several biomechanical parameters were recorded, including radius at highest concavity (Rhc) and defomation amplitude (DA)...
November 27, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29183834/contact-lens-to-measure-individual-ion-concentrations-in-tears-and-applications-to-dry-eye-disease
#16
Ramachandram Badugu, Bennie H Jeng, E Albert Reece, Joseph R Lakowicz
Dry eye disease (DED) affects millions of individuals in the United States and worldwide, and the incidence is increasing with an aging population. There is widespread agreement that the measurement of total tear osmolarity is the most reliable test, but this procedure provides only the total ionic strength and does not provide the concentration of each ionic species in tears. Here, we describe an approach to determine the individual ion concentrations in tears using modern silicone hydrogel (SiHG) contact lenses...
November 25, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/29182643/how-do-adults-and-teens-with-self-declared-autism-spectrum-disorder-experience-eye-contact-a-qualitative-analysis-of-first-hand-accounts
#17
Dominic A Trevisan, Nicole Roberts, Cathy Lin, Elina Birmingham
A tendency to avoid eye contact is an early indicator of Autism Spectrum Disorder (ASD), and difficulties with eye contact often persist throughout the lifespan. Eye contact difficulties may underlie social cognitive deficits in ASD, and can create significant social and occupational barriers. Thus, this topic has received substantial research and clinical attention. In this study, we used qualitative methods to analyze self-reported experiences with eye contact as described by teens and adults with self-declared ASD...
2017: PloS One
https://www.readbyqxmd.com/read/29182030/biomarkers-of-ocular-surface-disease-using-impression-cytology
#18
Suzanne Hagan
Impression cytology (IC) is a technique which permits the retrieval of the outermost layer of ocular surface cells via the use of various types of filters. It is a minimally invasive method of evaluating human conjunctival epithelial cell morphology in the diagnosis of dry eye disease, a common and distressing disorder associated with ageing, contact lens wear, autoimmune disorders and refractive (LASIK) surgery. IC may also be utilized in the diagnosis of other ocular diseases, such as keratoconus and thyroid orbitopathy...
November 28, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29180136/obstacle-circumvention-and-eye-coordination-during-walking-to-least-and-most-affected-side-in-people-with-parkinson-s-disease
#19
Fabio Augusto Barbieri, Paula Favaro Polastri, Lilian Teresa Bucken Gobbi, Lucas Simieli, Vinicius Ignácio Alota Pereira, André Macari Baptista, Gabriel Felipe Moretto, Carolina Menezes Fiorelli, Luis Felipe Itikawa Imaizumi, Sérgio Tosi Rodrigues
BACKGROUND: The mechanisms that contribute to gait asymmetry in people with Parkinson's disease (PD) are unclear, mainly during gait with greater environmental demand, such as when an obstacle is circumvented while walking. OBJECTIVE: The aim of this study was to investigate the effects of obstacle circumvention of the least and most affected side on motor and gaze behavior in people with PD under/without the effects of dopaminergic medication. METHODS: Fifteen people with PD and 15 matched-control individuals were instructed to walk along a pathway, at a self-selected velocity, and to circumvent an obstacle, avoiding contact with it...
November 24, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29176786/in-vivo-imaging-of-palisades-of-vogt-in-dry-eye-versus-normal-subjects-using-en-face-spectral-domain-optical-coherence-tomography
#20
Wajdene Ghouali, Rachid Tahiri Joutei Hassani, Zoubir Djerada, Hong Liang, Mohamed El Sanharawi, Antoine Labbé, Christophe Baudouin
PURPOSE: To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients. PATIENTS AND METHODS: Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT...
2017: PloS One
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