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https://www.readbyqxmd.com/read/29046205/-clinical-phenotype-and-genetic-analysis-of-med13l-syndrome
#1
Qing-Jie Meng, Xue-Lian He, Han Xiao, Qian Xia, Bo Bi, Yun Xiang
A boy aged 4 years and 2 months was found to have delayed language and motor development, instability of gait, poor eye contact, stereotyped behavior, and seizure at the age of 3 years. Physical examination showed special facial features, including plagiocephaly, blepharoptosis, wide nasal bridge, down-turned mouth corners at both sides, and low-set ears. There were only two knuckles at the little finger of the left hand. The anteroposterior and lateral films of the spine showed scoliosis; echocardiography showed ventricular septal defect; the Gesell Developmental Scale showed delayed language development and moderate intellectual disability; there were no abnormalities in the karyotype; genome-wide SNP arrays found a duplication in 12q24...
October 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29044738/overview-of-mechanisms-of-antibiotic-resistance-in-pseudomonas-aeruginosa-an-ocular-perspective
#2
REVIEW
Dinesh Subedi, Ajay Kumar Vijay, Mark Willcox
Treatment of Pseudomonas aeruginosa eye infections often becomes a challenge due to the ability of this bacterium to be resistant to antibiotics via intrinsic and acquired mechanisms. Transfer of resistance due to interchangeable genetic elements is an important mechanism for the rapid transfer of antibiotic resistance in this pathogen. As a result, drug-resistant strains are becoming increasingly prevalent worldwide. This review systematically analyses data from recent publications to describe the global prevalence and antibiotic sensitivity of ocular P...
October 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29044716/effect-of-central-corneal-thickness-on-intraocular-pressure-and-comparison-of-topcon-ct-80-non-contact-tonometry-with-goldmann-applanation-tonometry
#3
Tarannum Mansoori, Nagalla Balakrishna
BACKGROUND: To compare intraocular pressure (IOP) measurements obtained with the Topcon CT-80 non-contact tonometer (NCT) and Goldmann applanation tonometer (GAT), in different ranges of IOP in normal and glaucoma subjects, and to assess the influence of central corneal thickness (CCT) on the IOP measurements in Asian Indian eyes. METHODS: Four hundred and two eyes of 402 subjects (193 newly diagnosed primary open angle glaucoma [POAG] and 209 normal) were enrolled for this prospective study...
October 18, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29043113/simultaneous-tracking-of-cardiorespiratory-signals-for-multiple-persons-using-a-machine-vision-system-with-noise-artifact-removal
#4
Ali Al-Naji, Javaan Chahl
Most existing non-contact monitoring systems are limited to detecting physiological signs from a single subject at a time. Still, another challenge facing these systems is that they are prone to noise artifacts resulting from motion of subjects, facial expressions, talking, skin tone, and illumination variations. This paper proposes an efficient non-contact system based on a digital camera to track the cardiorespiratory signal from a number of subjects (up to six persons) at the same time with a new method for noise artifact removal...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29042641/unconscious-avoidance-of-eye-contact-in-autism-spectrum-disorder
#5
Apoorva Rajiv Madipakkam, Marcus Rothkirch, Isabel Dziobek, Philipp Sterzer
Atypical responses to direct gaze are one of the most characteristic hallmarks of autism spectrum disorder (ASD). The cause and mechanism underlying this phenomenon, however, have remained unknown. Here we investigated whether the atypical responses to eye gaze in autism spectrum disorder is dependent on the conscious perception of others' faces. Face stimuli with direct and averted gaze were rendered invisible by interocular suppression and eye movements were recorded from participants with ASD and an age and sex matched control group...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29040122/treatment-and-resolution-of-filamentary-keratitis-in-a-patient-with-stiff-person-syndrome
#6
Steven S Bae, Sonia N Yeung, Clara C Chan
PURPOSE: To report a rare case of filamentary keratitis associated with stiff person syndrome. METHODS: Case report. RESULTS: A 26-year-old woman with several autoimmune conditions was referred because of filamentary keratitis. Conservative management using lubrication, mucolytics, and bandage contact lenses failed to adequately relieve symptoms. Despite the addition of oral prednisone, cyclosporine, and azathioprine, the patient's condition persisted with numerous filaments and severe dry eye...
October 13, 2017: Cornea
https://www.readbyqxmd.com/read/29039228/evaluation-of-the-respiratory-tract-toxicity-of-ortho-phthalaldehyde-a-proposed-alternative-for-the-chemical-disinfectant-glutaraldehyde
#7
Natasha R Catlin, Cynthia J Willson, Matthew Stout, Grace E Kissling, Suramya Waidyanatha, Gregory L Baker, Barry K Hayden, Michael Wyde
ortho-Phthalaldehyde (OPA) is a high-level chemical disinfectant that is commonly used for chemical sterilization of dental and medical instruments as an alternative to glutaraldehyde, a known skin and respiratory sensitizer. Concern for safe levels of human exposure remains due to a lack of toxicity data as well as human case reports of skin and respiratory sensitization following OPA exposure. The present study evaluated the inhalational toxicity of OPA in Harlan Sprague-Dawley rats and B6C3F1/N mice. Groups of 10 male and female rats and mice were exposed to OPA by whole-body inhalation for 3 months at concentrations of 0 (control), 0...
October 17, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29037406/monitoring-changes-in-body-surface-temperature-associated-with-treadmill-exercise-in-dogs-by-use-of-infrared-methodology
#8
Maria Rizzo, Francesca Arfuso, Daniela Alberghina, Elisabetta Giudice, Matteo Gianesella, Giuseppe Piccione
The aim of this study was to evaluate the influence of moderate treadmill exercise session on body surface and core temperature in dog measured by means of two infrared instruments. Ten Jack Russell Terrier/Miniature Pinscher mixed-breed dogs were subjected to 15min of walking, 10min of trotting and 10min of gallop. At every step, body surface temperature (Tsurface) was measured on seven regions (neck, shoulder, ribs, flank, back, internal thigh and eye) using two different methods, a digital infrared camera (ThermaCam P25) and a non-contact infrared thermometer (Infrared Thermometer THM010-VT001)...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29034156/intraocular-lens-opacification-after-descemet-s-stripping-automated-endothelial-keratoplasty
#9
Meng-Sheng Lee, I-Lun Tsai, Ching-Yao Tsai, Li-Lin Kuo, Shiow-Wen Liou, Lin-Chung Woung
Compared with conventional penetrating keratoplasty, Descemet's stripping automated endothelial keratoplasty (DSAEK) more effectively maintain global integrity and rapid vision rehabilitation with less ocular surface disorders in patients with endothelial dysfunction. Here, we report a case of a 76-year-old woman who experienced opacification of a hydrophilic intraocular lens (IOL) approximately 10 months after DSAEK. The patient with no history of systemic disease developed pseudophakic bullous keratopathy in the right eye 2 years after undergoing cataract surgery...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29034154/intraocular-pressure-monitoring-by-rebound-tonometry-in-children-with-myopia
#10
Jenchieh Weng, I-Lun Tsai, Li-Lin Kuo, Ching-Yao Tsai, Lin-Chung Woung, Ya-Chuan Hsiao
BACKGROUND/PURPOSE: Topical atropine treatment is generally accepted to retard the progression of myopia, but it is associated with side effects such as photophobia and elevation of intraocular pressure (IOP). IOP measurements in children are challenging. The traditional applanation tonometry by direct contact with the cornea will require patient's cooperation. The rebound tonometer, using a dynamic electromechanical method for measuring IOP, shows good correlation with traditional tonometry...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29033270/a-survey-of-contact-lens-related-complications-in-a-tertiary-hospital-in-china
#11
Weiwei Li, Xuguang Sun, Zhiqun Wang, Yang Zhang
PURPOSE: To describe the type of complications related to contact lens (CL) wear in a tertiary hospital in XX, China. METHODS: A retrospective study of 141 patients who complained discomfort after wearing contact lens on an outpatient basis of XX Hospital were conducted from the January 2012 to December 2015. The data included patients' demographics, lens type, history, slit-lamp examination, reports of corneal scrapings, culture, and examination of in vivo confocal microscopy...
October 12, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29032921/treatment-of-contact-lens-related-dry-eye-with-antibacterial-honey
#12
Daniel Wong, Julie M Albietz, Huan Tran, Cimonette Du Toit, Anita Hui Li, Tina Yun, Jee Han, Katrina L Schmid
AIM: Contact lens induced dry eye affects approximately 50% of contact lens wearers. The aim was to assess the effects of Manuka (Leptospermum sp.) honey eye drops (Optimel, Melcare, Australia) on dry eye in contact lens wearers. The safety of the honey eye drops in contact lens wear and contact lens wearers' compliance were also evaluated. DESIGN: Prospective, randomised, cross over study, examiner masked, pilot treatment trial. METHODS: Twenty-four participants aged 20 to 55 years with contact lens related dry eye were recruited and randomised to two treatment groups; 20 completed the study...
October 9, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29032706/quality-and-predictors-of-diabetes-care-among-patients-with-schizophrenia-a-danish-nationwide-study
#13
Mette Jørgensen, Jan Mainz, Fabrizio Carinci, Reimar W Thomsen, Søren Paaske Johnsen
OBJECTIVE: Patients with schizophrenia have a high prevalence of diabetes, but data on diabetes care quality for these patients are limited. This nationwide study compared the quality of diabetes care among individuals with and without schizophrenia and identified predictors of care quality. METHODS: In a population-based cohort study, 83,813 individuals with diabetes seen at hospital outpatient clinics between 2005 and 2013, including 669 with comorbid schizophrenia, were identified from Danish registries...
October 16, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29029687/a-qualitative-study-of-copd-patients-experience-of-a-telemedicine-intervention
#14
Lene Nissen, Tove Lindhardt
BACKGROUND: Clinically stable patients with chronic obstructive pulmonary disease (COPD) are often followed at regular intervals regardless of the needs. Our aim was to investigate the patient perspective on receiving telemedicine with weekly submission of readings and regular video consultations (Net-COPD) as an alternative to visits in the respiratory outpatient clinic and investigating the role of telemedicine in management of severe COPD. DESIGN: Descriptive design and the method is qualitative based on semistructured interviews...
November 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29029132/general-practitioners-strategies-in-consultations-with-immigrants-in-norway-practice-based-shared-reflections-among-participants-in-focus-groups
#15
Stefán Hjörleifsson, Elise Hammer, Esperanza Díaz
Background: Immigrants comprise 16.8% of the population in Norway and meet General Practitioners (GPs) as their first point of contact with most health care services as do others in Norway. While Norwegian GPs are not trained in cultural competence, little is known about the extent to which they see good care for immigrants as relying on specific strategies. Objectives: To explore the thoughts of GPs in Norway about strategies they might use with immigrant patients...
September 28, 2017: Family Practice
https://www.readbyqxmd.com/read/29023313/mini-scleral-lenses-for-correction-of-refractive-errors-after-radial-keratotomy
#16
Hsiao-Sang Chu, I-Jong Wang, Grace A Tseng, Wei-Li Chen, Yu-Chih Hou, Fung-Rong Hu
OBJECTIVE: To evaluate the factors affecting clinical outcomes of correcting cumulative refractive errors or irregular astigmatism after radial keratotomy (RK) using mini-scleral lenses. METHODS: We retrospectively analyzed 36 eyes receiving mini-scleral lenses after RK from July 2011 to June 2016. Analyses included age, refractive errors, best spectacle-corrected visual acuity (BSCVA), best contact lens-corrected visual acuity (BCLCVA), topographic indices, RK treatment zone diameter (TZD), power difference (PrD) within the RK treatment zone, and decentration distance (DD) of the RK treatment zone center...
October 11, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29022964/nocardia-arthritidis-keratitis-case-report-and-review-of-the-literature
#17
Andrew Gieger, Stephen Waller, Joseph Pasternak
INTRODUCTION: Keratitis due to Nocardia infection is not commonly encountered in clinical practice and may therefore be mistaken for fungal or viral keratitis leading to delayed treatment and increased risk of permanent visual impairment. CASE: An otherwise healthy 27 years old Caucasian Active Duty military member presented to the clinic with three days of light sensitivity and irritation of his right eye. He carried a history of PRK in both eyes six years prior and admitted to recent contact lens overuse...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29022298/patient-awareness-of-cataract-and-age-related-macular-degeneration-among-the-korean-elderly-a-population-based-study
#18
Hankil Lee, Yong Jung Jang, Hyung Keun Lee, Hye Young Kang
PURPOSE: Age-related eye disease is often considered part of natural aging. Lack of awareness of eye conditions can result in missed treatment. We investigated the rates of awareness of cataract and age-related macular degeneration, the most common age-related eye-diseases, and the associated factors among elderly Koreans. METHODS: We identified 7,403 study subjects (≥40 years old) with cataract or age-related macular degeneration based on ophthalmic examination results during the 5th Korean National Health and Nutrition Examination Survey conducted between 2010 and 2012...
August 26, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29022291/comparison-of-contact-lens-corrected-quality-of-vision-and-life-of-keratoconus-and-myopic-patients
#19
Sunghoon Lee, Gangwook Jung, Hyung Keun Lee
PURPOSE: To compare and analyze changes in vision quality, subjective symptoms, and psycho-social satisfaction in keratoconus and myopic patients following the wearing of contact lenses. METHODS: This study enrolled 25 keratoconus and 25 myopic patients with corrected vision over 0.8 according to the Snellen chart due to treatment with contact lenses. Patients were surveyed prior to the wearing of contact lenses, and again after three months of contact lens usage with a questionnaire about quality of vision and life...
August 26, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29022163/comparison-of-central-corneal-thickness-with-four-different-optical-devices
#20
Kuddusi Teberik, Mehmet Tahir Eski, Murat Kaya, Handan Ankaralı
BACKGROUND: To compare the consistency between the average scores of the contact central corneal thickness measurements from ultrasound pachymetry devices still gold standard, such as iPac(®) and Echoscan US-500, and noncontact measurements via Pentacam HR and Sirius topography. METHODS: This prospective study, subsequently admitted to the ophthalmology department, 76 healthy individuals were performed. The measurements were repeated three times for each eye, and average scores were statistically analyzed on the same day and almost at the same time...
October 11, 2017: International Ophthalmology
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