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https://www.readbyqxmd.com/read/27931130/exposures-to-traditional-automatic-dishwashing-tablets-and-a-comparison-with-exposures-to-soluble-film-tablets-reported-to-the-united-kingdom-national-poisons-information-service-2008-2015
#1
Rachael Day, Michael Eddleston, Simon H L Thomas, John P Thompson, J Allister Vale
INTRODUCTION: Traditional automatic dishwashing tablets are contained within an external wrapper that requires removal prior to use. OBJECTIVE: To determine the toxicity of traditional tablets and to compare this with our previously reported experience of soluble film dishwashing tablets. METHODS: Telephone enquiries regarding traditional tablets were analysed retrospectively for the period January 2008 to December 2015. RESULTS: Traditional tablets: There were 503 enquiries relating to 492 patients who had been exposed to a traditional tablet...
December 8, 2016: Clinical Toxicology
https://www.readbyqxmd.com/read/27922101/social-determinants-of-eyeblinks-in-adult-male-macaques
#2
Sébastien Ballesta, Clayton P Mosher, Jeno Szep, Kate D Fischl, Katalin M Gothard
Videos with rich social and emotional content elicit natural social behaviors in primates. Indeed, while watching videos of conspecifics, monkeys engage in eye contact, gaze follow, and reciprocate facial expressions. We hypothesized that the frequency and timing of eyeblinks also depends on the social signals contained in videos. We monitored the eyeblinks of four male adult macaques while they watched videos of conspecifics displaying facial expressions with direct or averted gaze. The instantaneous blink rate of all four animals decreased during videos...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27914235/hyaluronan-as-a-promising-excipient-for-ocular-drug-delivery
#3
REVIEW
Michaela Guter, Miriam Breunig
Hyaluronan (HA) is a naturally occurring polysaccharide and well known for its exceptional properties such as high biocompatibility and biodegradability, along with a low immunogenicity. Besides its use for various biomedical applications it recently came into focus as a favorable excipient for the formulation of various ocular therapeutics. This review article summarizes the ocular distribution of HA and its most heavily investigated binding protein "cluster of differentiation 44" (CD44) which is the rationale for the clinical use of HA, primarily as an additive in ocular applications ranging from eye drops to contact lenses...
November 30, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27911426/-ocular-hydrodynamics-after-phacoemulsification-cataract-surgery-in-patients-with-primary-open-angle-glaucoma
#4
E A Kalizhnikova, O I Lebedev, O V Shchipacheva, G G Pecheritsa
AIM: To investigate parameters of intraocular fluid outflow after phacoemulsification of cataract in patients with primary open-angle glaucoma (POAG). MATERIAL AND METHODS: The study involved 153 cataract patients (153 eyes), most of whom also had POAG. The patients were divided into three groups: group 1 - 51 patients (51 eyes) with cataract but no glaucoma, group 2 - 51 patients (51 eyes) with cataract and early POAG, and group 3 - 51 patients (51 eyes) with cataract and advanced POAG...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27911424/-effectiveness-of-soft-contact-lenses-in-severe-keratoconjunctivitis-sicca-treated-with-local-immunosuppressive-therapy
#5
T N Safonova, O V Gladkova, V I Boev, A A Fedorov
AIM: To study the effectiveness of soft contact lenses in severe keratoconjunctivitis sicca (KCS) treated with local immunosuppressive therapy. MATERIAL AND METHODS: We have examined 41 patients (60 eyes) with severe KCS, including 3 men (4 eyes) and 38 women (56 eyes) aged from 27 to 76 years. Group 1 consisted of 22 persons (30 eyes) who were prescribed cyclosporine А 0.05% instillations 2 times daily, artificial tears, and soft contact lenses. Group 2 consisted of 19 patients (30 eyes) who received instillations of cyclosporine А 0...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27909310/undiluted-serum-eye-drops-for-the-treatment-of-persistent-corneal-epitheilal-defects
#6
Kaevalin Lekhanont, Passara Jongkhajornpong, Thunyarat Anothaisintawee, Varintorn Chuckpaiwong
Several studies found that 50-100% serum eye drops provided greater benefits without inducing detrimental effects on the corneal epithelial healing. This study assessed the efficacy of undiluted serum eye drops for the treatment of persistent corneal epithelial defects (PED). A total of 109 eyes received 100% serum eye drops for PED were recruited into this study. The data were compared with an historical control group of 79 eyes with PED who received conventional treatments from 2006-2011 at the same institution...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27908604/compatibility-of-phospholipid-liposomal-spray-with-silicone-hydrogel-contact-lens-wear
#7
Michael T M Wang, Kalaivarny Ganesalingam, Chee Seang Loh, Trisha Alberquerque, Suhaila Al-Kanani, Stuti L Misra, Jennifer P Craig
PURPOSE: To assess the effects of two weeks of regular phospholipid liposomal spray application on lipid layer grade, tear film stability, subjective comfort, visual acuity, and lipid deposition in silicone hydrogel contact lens wearers. METHODS: Thirty-one existing contact lens wearers were enrolled and fitted with two week planned replacement silicone hydrogel contact lenses (Acuvue(®) Oasys(®)) in a prospective, randomized, paired-eye, investigator-masked trial...
November 28, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27902849/oral-antivirals-for-preventing-recurrent-herpes-simplex-keratitis-in-people-with-corneal-grafts
#8
REVIEW
Uday K Bhatt, M N Abdul Karim, Jeremy I Prydal, Senthil V Maharajan, Usama Fares
BACKGROUND: Ocular herpes is a viral infection of the eye caused by the herpes simplex virus (HSV), a double-stranded DNA virus. Corneal scarring caused by herpes simplex keratitis (HSK) is the leading infectious cause of penetrating corneal graft in high-income countries. Acyclovir is an antiviral drug known to have a protective effect against recurrences in herpetic eye disease. While there are some studies which have evaluated the effects of intervention with oral antiviral in preventing such recurrences in people with corneal grafts, a systematic review of all comparative clinical trials has not been previously undertaken...
November 30, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27898517/comparision-of-optical-low-coherence-reflectometry-versus-ultrasonic-biometry-in-high-hypermetropia
#9
Rukiye Aydin, Sevil Karaman Erdur, Kubra Serefoglu Cabuk, Eyyup Karahan, Suleyman Kaynak
PURPOSE: To compare anterior chamber depth (ACD), axial length (AL), and lens thickness (LT) measurements obtained by the Lenstar LS 900 (Haag-Streit AG) optical low-coherence reflectometry with those obtained by the A-scan contact ultrasound among patients with moderate and high hypermetropia. METHODS: Fifty-two eyes of 52 patients with moderate and high hypermetropia (spherical equivalent of +4 D or more) were examined in this study measurements of ACD, AL, and LT obtained by Lenstar were compared with those obtained by applanation A-scan ultrasound...
November 24, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27898448/laser-vision-correction-in-treating-myopia
#10
Germano Leal Ehlke, Ronald R Krueger
Myopia is a generally benign refractive error with an increasing prevalence worldwide. It can be corrected temporarily with glasses and contact lenses and permanently with laser vision correction. The 2 main procedures currently being performed for myopia correction are photorefractive keratectomy and laser-assisted in situ keratomileusis. Each technique has its advantages, but they appear to yield similar visual outcomes 1 year after surgery. Laser vision correction for myopia was considered a paradigm shift because healthy eyes could now undergo a surgical procedure to permanently and safely correct the error by altering the center of the cornea, which was previously off limits because of the potential for loss of transparency...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27898446/topical-atropine-in-the-control-of-myopia
#11
Donald Tan, Su Ann Tay, Kai-Lyn Loh, Audrey Chia
Efforts to reduce myopia progression in childhood are driven by the increasing incidence of high myopia and its attendant health risks. Interventional approaches to reduce myopia progression in childhood have included the use of spectacles, contact lens, and pharmacological methods, of which the latter appear to be most promising. We review the use of topical atropine eye drops in the retardation of myopia progression in children and discuss the efficacy and safety profiles when used at different concentrations (1...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27896441/pterygium-surgery-using-the-principle-of-contact-inhibition-results-of-13-years-experience
#12
Tsutomu Hara, Takako Hashimoto, Takeshi Hara
PURPOSE: To report a technique to prevent pterygium recurrence using the principle of contact inhibition. METHODS: Two hundred and fifteen patients (232 eyes; average age, 64.1 years) with primary pterygia who underwent pterygium surgery at the Hara Eye Hospital between 1999 and 2012. We retrospectively evaluated the patients who underwent the following procedure to prevent pterygium recurrence. The surface conjunctiva on the pterygium body was not removed. After removing the pterygium body, by placing a narrow pedicle autoconjunctival flap along the corneal limbus and tying it tightly to the front area of the residual conjunctiva, there is no room for the active residual tissue to proliferate, thus preventing a recurrence by contact inhibition...
November 28, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27895903/deliberate-exposure-of-humans-to-chlorine-the-aftermath-of-ebola-in-west-africa
#13
Shaheen Mehtar, Andre N H Bulabula, Haurace Nyandemoh, Steve Jambawai
BACKGROUND: During the recent Ebola outbreak, spraying of the environment and humans, including healthcare workers, with chlorine was wide spread in affected African countries; adverse clinical effects are reported here. METHODS: A cross sectional survey by interview of 1550 volunteers consisting of 500 healthcare workers (HCW), 550 Ebola survivors (EVD) and 500 quarantined asymptomatic Ebola contacts (NEVD) was conducted. Demographics, frequency of exposure to chlorine, clinical condition after chlorine exposure particularly eye, respiratory and skin conditions were noted...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27894302/anti-inflammatory-and-burn-injury-wound-healing-properties-of-the-shell-of-haliotis-diversicolor
#14
Zhi-Cheng Chen, Shing-Yi Sean Wu, Wei-Yang Su, Yuan-Chuan Lin, Yi-Hsin Lee, Wei-Hao Wu, Chun-Hong Chen, Zhi-Hong Wen
BACKGROUND: The shell of Haliotis diversicolor, or shijueming (SJM), is a type of traditional Chinese medicine. The SJM has appeared in historical records as early as the third and fourth centuries. Historical records have revealed that SJM had mainly been used to treat eye diseases. After the Qing Dynasty (1757), records had emerged, detailing the use of SJM for treating skin injuries, particularly for treating poorly managed ulcers or traumatic wounds. Furthermore, in our anti-inflammation-screening system, SJM significantly inhibited the expression of pro-inflammatory proteins...
November 28, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27891163/the-visual-system-of-harvestmen-opiliones-arachnida-chelicerata-a-re-examination
#15
Tobias Lehmann, Eva Lodde-Bensch, Roland R Melzer, Martina Metz
BACKGROUND: The visual systems in chelicerates are poorly understood, even though they show strong variation in eye and visual neuropil architecture, thus may provide valuable insights for the understanding of chelicerate phylogeny and eye evolution. Comparable morphological characters are desperately sought for reconstructions of the phylogeny of Chelicerata, especially with respect to Arachnida. So far, reliable data exist only for Pycnogonida, Xiphosura, Scorpiones, and Araneae. The few earlier studies of the organisation of the visual system in harvestmen are contradictory concerning the number, morphology, and position of the visual neuropils...
2016: Frontiers in Zoology
https://www.readbyqxmd.com/read/27884616/mechanical-properties-of-contact-lenses-the-contribution-of-measurement-techniques-and-clinical-feedback-to-50-years-of-materials-development
#16
REVIEW
Tarnveer Singh Bhamra, Brian J Tighe
PURPOSE: This review summarises the way in which mechanical property measurements combined with clinical perception have influenced the last half century of materials evolution in contact lens development. METHODS: Literature concerning the use of in-vitro testing in assessment of the mechanical behaviour of contact lenses, and the mutual deformation of the lens material and ocular tissue was examined. Tensile measurements of historic and available hydrogel lenses have been collected, in addition to manufacturer-generated figures for the moduli of commercial silicone hydrogel lenses...
November 21, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27883950/the-effects-of-social-pressure-and-emotional-expression-on-the-cone-of-gaze-in-patients-with-social-anxiety-disorder
#17
Johannes Harbort, Julia Spiegel, Michael Witthöft, Heiko Hecht
BACKGROUND AND OBJECTIVES: Patients with social anxiety disorder suffer from pronounced fears in social situations. As gaze perception is crucial in these situations, we examined which factors influence the range of gaze directions where mutual gaze is experienced (the cone of gaze). METHODS: The social stimulus was modified by changing the number of people (heads) present and the emotional expression of their faces. Participants completed a psychophysical task, in which they had to adjust the eyes of a virtual head to gaze at the edge of the range where mutual eye-contact was experienced...
November 12, 2016: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/27879499/impact-of-spherical-aberration-terms-on-multifocal-contact-lens-performance
#18
Cathleen Fedtke, Jennifer Sha, Varghese Thomas, Klaus Ehrmann, Ravi C Bakaraju
PURPOSE: To investigate the impact of the primary (PSA) and secondary (SSA) spherical aberration terms on visual performance (VP) in presbyopes, as measured using multifocal (MFCL) soft contact lenses on eye. METHODS: Seventeen presbyopes (age: 55.1 ± 6.9 years) wore seven commercial lenses (four center-near (MFCL N), one center-distance (MFCL D), one bifocal, and one single vision control). Unaided and with each lens on eye, the PSA and SSA terms were obtained with an aberrometer, the BHVI-EyeMapper (low illumination, natural and 4 mm pupil diameter)...
November 22, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27874294/dacryoadenitis-and-extraocular-muscle-inflammation-associated-with-contact-lens-related-acanthamoeba-keratitis-a-case-report-and-review-of-the-literature
#19
Tomris Sengor, Erdal Yuzbasioglu, Sevda Aydın Kurna, Murat Irkec, Ahmet Altun, Kubra Kökcen, Nazli Gul Yalcin
The present report discusses a new case of dacryoadenitis with extraocular muscle inflammation associated with Acanthamoeba keratitis (AK) in a contact lens wearer. A 41-year-old male, who has worn silicone hydrogel contact lenses on an extended basis for about 10 years, attended with the complaints of vision disturbance, hyperemia, and pain in his right eye. His history revealed that 1.5 month ago, he had been diagnosed with allergic conjunctivitis and had used steroid eye drops. Biomicroscopic examination revealed eyelid edema, chemosis, and ring infiltration, radial keratoneuritis and an epithelial defect in the cornea...
November 22, 2016: Orbit
https://www.readbyqxmd.com/read/27871357/contact-urticaria-with-paraphenylene-diamine-rare-or-underreported
#20
Muthu Sendhil Kumaran, Tarun Narang, Davinder Parsad
A 45-year old woman presented with a 2-day history of intensely itchy, erythematous wheals over her scalp and around her eyes, ears, and front of the chest. She had applied hair color and immediately developed hives on the scalp, face, and chest with rhinitis and redness in the eyes. The lesions recovered within a half hour of taking a cetirizine 10-mg tablet. She gave a similar history around three times in the past 6 months. She used a different brand of hair color every time but all were associated with the same symptoms...
2016: Skinmed
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