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https://www.readbyqxmd.com/read/28102563/multiscale-modeling-methods-in-biomechanics
#1
REVIEW
Pinaki Bhattacharya, Marco Viceconti
More and more frequently, computational biomechanics deals with problems where the portion of physical reality to be modeled spans over such a large range of spatial and temporal dimensions, that it is impossible to represent it as a single space-time continuum. We are forced to consider multiple space-time continua, each representing the phenomenon of interest at a characteristic space-time scale. Multiscale models describe a complex process across multiple scales, and account for how quantities transform as we move from one scale to another...
January 19, 2017: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/28101329/association-between-sports-type-and-overuse-injuries-of-extremities-in-adults-a-systematic-review
#2
REVIEW
Charlène Chéron, Christine Le Scanff, Charlotte Leboeuf-Yde
BACKGROUND: Sports injuries are often described as overuse or traumatic. Little is known about the frequency of overuse injuries and, in particular, if they vary between different types of sporting activities. PURPOSE: To identify any differences between sports in relation to diagnoses of overuse injuries of the extremities (OIE) and anatomical areas most likely to be injured in adults and to compare these findings with those reported in youngsters, as identified in a previous review...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/28100264/cross-sectional-examination-of-musculoskeletal-conditions-and-multimorbidity-influence-of-different-thresholds-and-definitions-on-prevalence-and-association-estimates
#3
Dianne B Lowe, Michael J Taylor, Sophie J Hill
BACKGROUND: Multimorbidity and musculoskeletal conditions create substantial burden for people and health systems. Quantifying the extent of co-occurring conditions is hampered by conceptual heterogeneity, imprecision and/or indecision about how multimorbidity is defined. The purpose of this study is to examine the influence of different ways of operationalising multimorbidity on multimorbidity prevalence rates with a focus on working-age adults with musculoskeletal conditions. Weighted population prevalence rates of multimorbidity among working-age Australians were estimated using data from the National Health Survey...
January 18, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28100231/can-screening-instruments-accurately-determine-poor-outcome-risk-in-adults-with-recent-onset-low-back-pain-a-systematic-review-and-meta-analysis
#4
Emma L Karran, James H McAuley, Adrian C Traeger, Susan L Hillier, Luzia Grabherr, Leslie N Russek, G Lorimer Moseley
BACKGROUND: Delivering efficient and effective healthcare is crucial for a condition as burdensome as low back pain (LBP). Stratified care strategies may be worthwhile, but rely on early and accurate patient screening using a valid and reliable instrument. The purpose of this study was to evaluate the performance of LBP screening instruments for determining risk of poor outcome in adults with LBP of less than 3 months duration. METHODS: Medline, Embase, CINAHL, PsycINFO, PEDro, Web of Science, SciVerse SCOPUS, and Cochrane Central Register of Controlled Trials were searched from June 2014 to March 2016...
January 19, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28099968/musculoskeletal-ultrasound-and-esper
#5
Fernando Saraiva
No abstract text is available yet for this article.
October 2016: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28099615/do-you-know-this-syndrome-dyspigmentation-along-the-blaschko-lines-caused-by-trisomy-7-mosaicism
#6
Miguel Pinto de Gouveia, Inês Coutinho, Vera Teixeira, Renata d'Oliveira, Margarida Venâncio, Ana Moreno
Dyspigmentation along the Blaschko lines is strongly suggestive of a mosaic skin disorder. We report a 9-year-old male patient who presented with swirls and streaks of both hypo and hyperpigmentation involving the entire body. Additionally, he had hypertrichosis, musculoskeletal and minor neurodevelopment abnormalities but no intellectual disability. Cultured fibroblast displayed trisomy 7 mosaicism, which can explain this pigmentary phenotype. Widespread dyspigmentation associated with involvement of other organs should prompt systemic examination to detect additional anomalies and genetic evaluation should be considered, even with normal fetal karyotype...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28099310/national-institutes-of-health-funding-to-departments-of-orthopaedic-surgery-at-u-s-medical-schools
#7
Jason Silvestre, Jaimo Ahn, L Scott Levin
BACKGROUND: The National Institutes of Health (NIH) is the largest supporter of biomedical research in the U.S., yet its contribution to orthopaedic research is poorly understood. In this study, we analyzed the portfolio of NIH funding to departments of orthopaedic surgery at U.S. medical schools. METHODS: The NIH RePORT (Research Portfolio Online Reporting Tools) database was queried for NIH grants awarded to departments of orthopaedic surgery in 2014. Funding totals were determined for award mechanisms and NIH institutes...
January 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28097503/blended-chitosan-paste-for-infection-prevention-preliminary-and-preclinical-evaluations
#8
Joel M Berretta, Jessica A Jennings, Harry S Courtney, Karen E Beenken, Mark S Smeltzer, Warren O Haggard
BACKGROUND: Local drug delivery devices offer a promising method for delivering vancomycin and amikacin for musculoskeletal wounds. However, current local delivery devices such as beads and sponges do not necessarily allow for full coverage of a wound surface with eluted antibiotics and do not address the need for reducing the antibiotic diffusion distance to help prevent contamination by bacteria or other microorganisms. We blended chitosan/polyethylene glycol (PEG) pastes/sponges to increase biocompatibility and improve antibiotic coverage within the wound...
January 17, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28096901/exploring-musculoskeletal-injuries-in-the-podiatry-profession-an-international-cross-sectional-study
#9
Cylie M Williams, Stefania Penkala, Peter Smith, Terry Haines, Kelly-Ann Bowles
BACKGROUND: Workplace injury is an international costly burden. Health care workers are an essential component to managing musculoskeletal disorders, however in doing this, they may increase their own susceptibility. While there is substantial evidence about work-related musculoskeletal disorders across the health workforce, understanding risk factors in specific occupational groups, such as podiatry, is limited. The primary aim of this study was to determine the prevalence and intensity of work related low back pain in podiatrists...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28096718/diffuse-large-b-cell-lymphoma-in-the-era-of-precision-oncology-how-imaging-is-helpful
#10
REVIEW
Hina J Shah, Abhishek R Keraliya, Jyothi P Jagannathan, Sree Harsha Tirumani, Vikram R Lele, Pamela J DiPiro
Diffuse large B cell lymphoma (DLBCL) is the most common histological subtype of Non-Hodgkin's lymphoma. As treatments continues to evolve, so do imaging strategies, and positron emission tomography (PET) has emerged as the most important imaging tool to guide oncologists in the diagnosis, staging, response assessment, relapse/recurrence detection,and therapeutic decision making of DLBCL. Other imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, and conventional radiography are also used in the evaluation of lymphoma...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28096256/chronic-symptoms-in-a-representative-sample-of-community-dwelling-older-people-a-cross-sectional-study-in-switzerland
#11
Yves Henchoz, Christophe Büla, Idris Guessous, Nicolas Rodondi, René Goy, Maurice Demont, Brigitte Santos-Eggimann
OBJECTIVES: The burden of multiple diagnoses is well documented in older people, but less is known about chronic symptoms, many of which are even not brought to medical attention. This study aimed to determine the prevalence of chronic symptoms, their relationships with disability in basic activities of daily living (BADL) and quality of life (QoL), and their public health impact. DESIGN: A large cross-sectional population-based study. SETTING: Community in 2 regions of French-speaking Switzerland...
January 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28096255/sheppheartcabg-trial-comprehensive-early-rehabilitation-after-coronary-artery-bypass-grafting-a-protocol-for-a-randomised-clinical-trial
#12
Ida Elisabeth Højskov, Philip Moons, Niels Viggo Hansen, Søren La Cour, Peter Skov Olsen, Christian Gluud, Per Winkel, Jane Lindschou, Lau Caspar Thygesen, Ingrid Egerod, Selina Kikkenborg Berg
INTRODUCTION: Patients undergoing coronary artery bypass graft surgery often experience a range of symptoms. Studies indicate that non-pharmacological interventions such as exercise training and psychoeducation have a positive physiological and psychological effect in early outpatient rehabilitation. The SheppHeartCABG trial will investigate the effect of early comprehensive rehabilitation in early phase rehabilitation versus usual care. The aim of this paper is to present the protocol for the SheppHeartCABG trial...
January 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28096253/generic-prognostic-factors-for-musculoskeletal-pain-in-primary-care-a-systematic-review
#13
Majid Artus, Paul Campbell, Christian D Mallen, Kate M Dunn, Danielle A W van der Windt
OBJECTIVES: To summarise the evidence for generic prognostic factors across a range of musculoskeletal (MSK) conditions. SETTING: primary care. METHODS AND OUTCOMES: Comprehensive systematic literature review. MEDLINE, CINAHL, PsychINFO and EMBASE were searched for prospective cohort studies, based in primary care (search period-inception to December 2015). Studies were included if they reported on adults consulting with MSK conditions and provided data on associations between baseline characteristics (prognostic factors) and outcome...
January 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28096027/work-related-musculoskeletal-disorders-in-primary-health-care-nurses
#14
Tânia Ribeiro, Florentino Serranheira, Helena Loureiro
BACKGROUND: Work related musculoskeletal disorders (WRMSDs) constitute a serious occupational health problem among registered nurses (RN) all around the world. Its prevalence is mainly associated with nurses' high physical demands that still remain poorly studied in primary health care (PHC). PURPOSE: To describe nurses' self-reported symptoms of WRMSDs (mainly discomfort and pain) in PHC, featuring the main work tasks that may have risk factors for its development...
February 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28095751/crispr-based-epigenome-editing-of-cytokine-receptors-for-the-promotion-of-cell-survival-and-tissue-deposition-in-inflammatory-environments
#15
Niloofar Farhang, Jonathan M Brunger, Joshua D Stover, Pratiksha I Thakore, Brandon Lawrence, Farshid Guilak, Charles A Gersbach, Lori A Setton, Robert D Bowles
Musculoskeletal diseases have been associated with inflammatory cytokine action, particularly action by TNF-α and IL-1β. These inflammatory cytokines promote apoptosis and senescence of cells in diseased tissue and extracellular matrix breakdown. Stem cell-based therapies are being considered for the treatment of musculoskeletal diseases, but the presence of these inflammatory cytokines will have similar deleterious action on therapeutic cells delivered to these environments. Methods that prevent inflammatory-induced apoptosis and pro-inflammatory signaling, in cell and pathway specific manners are needed...
January 17, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28094592/association-among-work-related-musculoskeletal-disorders-job-stress-and-job-attitude-of-occupational-therapists
#16
Jin-Hyuck Park, Ji-Hyuk Park
This study was conducted to investigate the associations among work-related musculoskeletal disorders (WMSDs), job stress, and job attitude of occupational therapists in South Korea. Self-reporting questionnaires were distributed to 150 occupational therapists. Of the 128 occupational therapists who responded, 110 (85.9%) reported WMSDs affecting at least one body site. The most affected WMSDs site was the low back (26.8%), and the most reported number of body site affected by WMSDs was one (53.9%). As a result, there were significant differences in job stress and job attitude depending on the age, work experience, working hour, presence or absence of WMSDs, and number of site of pain...
January 17, 2017: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/28094208/multidisciplinary-assessment-of-post-ebola-sequelae-in-guinea-postebogui-an-observational-cohort-study
#17
Jean-François Etard, Mamadou Saliou Sow, Sandrine Leroy, Abdoulaye Touré, Bernard Taverne, Alpha Kabinet Keita, Philippe Msellati, N'Fally Magassouba, Sylvain Baize, Hervé Raoul, Suzanne Izard, Cécé Kpamou, Laura March, Ibrahima Savane, Moumié Barry, Eric Delaporte
BACKGROUND: The high number of survivors from the 2013-16 west African outbreak of Ebola virus disease (EVD) has raised several new issues: long-term clinical complications, psychosocial consequences, risks of EVD reactivation, and secondary transmission due to viral persistence in body fluids. We aimed to assess long-term clinical, psychosocial, and viral outcomes in EVD survivors in Guinea. METHODS: In this multidisciplinary observational cohort study, we recruited patients aged 1 year or more in four sites in Guinea (Donka National Hospital, Conakry; Macenta Prefectoral Hospital, Macenta; N'zérékoré Regional Hospital, N'zérékoré; and Forécariah Prefectoral Hospital, Forécariah) following discharge from any Ebola treatment centre in Guinea...
January 13, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28093618/mri-assessment-of-calf-injuries-in-australian-football-league-players-findings-that-influence-return-to-play
#18
George Waterworth, Sara Wein, Alexandra Gorelik, Andrew H Rotstein
OBJECTIVE: Calf muscle strains have become increasingly prevalent in recent seasons of the Australian Football League (AFL) and represent a significant cause of time lost from competition. The purpose of this study was to examine the association between MRI features of calf muscle strains and games missed and to thereby identify parameters that are of prognostic value. MATERIALS AND METHODS: A retrospective analysis of MRI scans of AFL players with calf strains referred to a musculoskeletal radiology clinic over a 5-year period (2008-2012) was performed...
January 16, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28093371/sonographically-guided-knee-meniscus-injections-feasibility-techniques-and-validation
#19
Michael R Baria, Jacob L Sellon, Dan Lueders, Jay Smith
BACKGROUND: There is a growing interest in the use of biologic agents such as platelet-rich plasma and mesenchymal stem/stromal cells to treat musculoskeletal injuries, including meniscal tears. Although prior research has documented the role of diagnostic ultrasound to evaluate meniscal tears, sonographically guided (SG) techniques to specifically deliver therapeutic agents into the meniscus have not been described. OBJECTIVE: To describe and validate SG injection techniques for the body and posterior horn of the medial and lateral meniscus...
January 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28092566/wake-up-exoskeleton-to-assist-children-with-cerebral-palsy-design-and-preliminary-evaluation-in-level-walking
#20
Fabrizio Patane, Stefano Rossi, Fausto Del Sette, Juri Taborri, Paolo Cappa
This paper presents the modular design and control of a novel compliant lower limb multi-joint exoskeleton for the rehabilitation of ankle knee mobility and locomotion of pediatric patients with neurological diseases, such as Cerebral Palsy (CP). The device consists of an untethered powered knee-ankle-foot orthosis (KAFO), addressed as WAKE-up (Wearable Ankle Knee Exoskeleton), characterized by a position control and capable of operating synchronously and synergistically with the human musculoskeletal system...
January 11, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
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