keyword
https://read.qxmd.com/read/38536143/new-book-examines-the-roots-implications-of-the-nocebo-effect-and-strategies-to-address
#1
JOURNAL ARTICLE
Mary Korr
No abstract text is available yet for this article.
April 1, 2024: Rhode Island Medical Journal
https://read.qxmd.com/read/38533458/translating-knowledge-on-placebo-and-nocebo-effects-into-clinical-practice
#2
JOURNAL ARTICLE
Elif Buse Caliskan, Ulrike Bingel, Angelika Kunkel
INTRODUCTION: Positive and negative treatment expectations are powerful modulators of health and treatment outcomes. A substantial part of treatment success is due to contextual factors modulating patient's expectations towards a treatment. Consequently, treatment expectations should be a target of therapeutic interventions themselves. OBJECTIVES: This article highlights the neurobiological underpinnings of treatment expectations as well as strategies to modulate contextual factors to optimize treatment outcomes in daily clinical settings...
April 2024: Pain Reports
https://read.qxmd.com/read/38533223/effects-of-golf-instructors-professional-certification-levels-on-amateur-golfers-perception-of-instructor-expertise-instructor-credibility-and-lesson-participation-intention-testing-placebo-and-nocebo-effects
#3
JOURNAL ARTICLE
Hye Jin Yang, Ji-Hye Yang, Si Cheol Jung, Chulhwan Choi, Chul-Ho Bum
This study investigated the differences in amateur golfers' perceptions of instructor expertise, instructor credibility, and lesson participation intention depending on the golf instructor's certification level to investigate whether placebo and nocebo effects exist depending on the certification level. Accordingly, the study analyzed 153 amateur golfers with at least 1 year of playing experience, and the results were as follows: First, there was a difference in the perception of instructor expertise among amateur golfers depending on the golf instructor's certification level...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38483082/discontinuation-of-fumaric-acid-esters-is-affected-by-depressive-symptomatology-a-retrospective-analysis
#4
JOURNAL ARTICLE
Frederik Krefting, Stefanie Hölsken, Manfred Schedlowski, Wiebke Sondermann
Fumaric acid esters (FAEs) remain a widespread therapy option for moderate-to-severe psoriasis. However, drug survival of FAEs is limited by adverse events (AEs) or inadequate treatment response. Depressive disturbances are highly prevalent in psoriasis patients and are hypothesized to be associated with the reporting of AEs and therapy discontinuation. This study's aim was to analyze whether psoriasis patients with comorbid depressive symptomatology are more likely to discontinue treatment with FAEs due to AEs and/or inadequate treatment response...
March 14, 2024: Acta Dermato-venereologica
https://read.qxmd.com/read/38444432/landau-model-for-illustrating-the-learning-and-unlearning-process-of-nociplastic-pain
#5
JOURNAL ARTICLE
Belén Valenzuela
Recent advancements in understanding the consolidation of nociplastic pain point to a complex, non-conscious learned process of threat perception. Neurobiological pain education is emerging as a promising approach to unlearn nociplastic pain, supported by biopsychosocial tools such as exposure to movement, mindfulness, and group sharing formats. However, this approach is still not well-known among clinicians and the society at large, creating a communication problem that unfortunately perpetuates the suffering of patients...
2024: Front Pain Res (Lausanne)
https://read.qxmd.com/read/38436916/treatment-persistence-and-switching-patterns-of-adalimumab-biosimilar-abp-501-in-european-patients-with-rheumatologic-diseases
#6
JOURNAL ARTICLE
Ran Jin, Silvia Kruppert, Florian Scholz, Isabelle Bardoulat, Khalil Karzazi, Francois Morand, Greg Kricorian, David Collier, Jonathan Kay
INTRODUCTION: ABP 501 was an adalimumab (ADA) biosimilar approved for treating immune-mediated inflammatory diseases (IMIDs) including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). In this retrospective study, we aimed to examine the treatment patterns of ABP 501 among patients with these IMIDs using German and French pharmacy claims databases. METHODS: Patients with RA, PsA, or AS who initiated ABP 501 between October 2018 and March 2020 and were observed continuously for ≥ 365 days both before and after ABP 501 initiation were included...
March 4, 2024: Rheumatology and Therapy
https://read.qxmd.com/read/38372189/development-and-validation-of-the-pharmacological-statin-associated-muscle-symptoms-risk-stratification-score-using-electronic-health-record-data
#7
JOURNAL ARTICLE
Boguang Sun, Pui Ying Yew, Chih-Lin Chi, Meijia Song, Matt Loth, Yue Liang, Rui Zhang, Robert J Straka
Statin-associated muscle symptoms (SAMS) can lead to statin nonadherence. This paper aims to develop a pharmacological SAMS risk stratification (PSAMS-RS) score using a previously developed PSAMS phenotyping algorithm that distinguishes objective vs. nocebo SAMS using electronic health record (EHR) data. Using our PSAMS phenotyping algorithm, SAMS cases and controls were identified from Minnesota Fairview EHR, with the statin user cohort divided into derivation (January 1, 2010, to December 31, 2018) and validation (January 1, 2019, to December 31, 2020) cohorts...
February 19, 2024: Clinical Pharmacology and Therapeutics
https://read.qxmd.com/read/38371054/a-psychological-exploration-of-the-power-of-our-mindset-and-its-influence-on-physiological-health
#8
REVIEW
Parmis Parsamanesh, Mykhailo Vysochyn
The brain is the control center for our bodies and determines our emotions, thoughts, and actions. From a psychological perspective, the mind can assist humans in manifesting a more remarkable life for themselves or hinder their abilities and result in unfulfilled potential. Considering the power of the mind, it is interesting to study the psychology of the mind and its direct influence on our physiological health. In medical terms, this effect is known as the placebo effect, where the mind and body connect on a stronger level and can assist in the betterment of an individual's physiological health...
January 2024: Curēus
https://read.qxmd.com/read/38363817/impairment-of-hypnosis-by-nocebo-response-and-related-neurovegetative-changes-a-case-report-in-oral-surgery
#9
JOURNAL ARTICLE
Luca Queirolo, Enrico Facco, Christian Bacci, Carla Mucignat, Gastone Zanette
This article presents the third molar removal in a highly hypnotizable patient, who had been successfully submitted to oral surgery with hypnosis as stand-alone anesthesia in previous sessions. Unexpectedly, hypnosis initially failed, as a result of a nocebo response due to a previous dentist's bad communication; two complaints made by the patient were associated with increased sympathetic activity (as defined by increased heart rate and electrodermal activity and decreased heart rate variability). After deepening of hypnosis, the patient achieved a full hypnotic analgesia allowing for a successful conclusion of the intervention, an event associated with decreased heart rate, electrodermal activity, and increased heart rate variability...
February 16, 2024: International Journal of Clinical and Experimental Hypnosis
https://read.qxmd.com/read/38357430/health-scares-tracing-their-nature-growth-and-spread
#10
JOURNAL ARTICLE
Kate MacKrill, Michael Witthöft, Simon Wessely, Keith J Petrie
BACKGROUND: Health scares are highly publicised threats to health that increase public concern and protective behaviours but are later shown to be unfounded. Although health scares have become more common in recent times, they have received very little research attention. This is despite the fact that health scares often have negative outcomes for individuals and community by affecting health behaviours and causing high levels of often unnecessary anxiety. METHOD: In this paper we undertook a review and analysis of the major types of health scares as well as the background factors associated with health scares and their spread...
December 2023: Clin Psychol Eur
https://read.qxmd.com/read/38354014/-nocebo-placebo-the-hidden-side-of-our-treatments
#11
JOURNAL ARTICLE
Daniel Annequin
NOCEBO PLACEBO, THE HIDDEN SIDE OF OUR TREATMENTS. Our knowledge of the placebo effect and its opposite, the nocebo effect, has changed dramatically in the last 20 years. Any treatment activity induces this type of effect. The placebo groups in clinical studies have biases that profoundly alter their neutrality. The nocebo effect is omnipresent in daily practice, it contributes to induce many of the adverse drug effects. The use of «impure» placebos is also widespread in daily practice. The placebo effect has an objectivable and reproducible neurobiological substrate...
October 2023: La Revue du Praticien
https://read.qxmd.com/read/38316098/-does-patient-communication-influence-kinesiophobia-a-systematic-review
#12
REVIEW
C Pita-Martínez, L A Justo-Cousiño
The aim of the present systematic review was to determine the effect of communication in the health care setting on kinesiophobia. To this end, a literature search was conducted in seven databases between November 2022 and February 2023. The review was carried out following the PRISMA statement and for the analysis of methodological quality we used: PEDro Scale, Van Tulder criteria and risk of bias analysis of the Cochrane Collaboration. A total of 13 articles were included with a mean methodological quality of 7...
February 4, 2024: Rehabilitación
https://read.qxmd.com/read/38269448/confirmation-of-covid-19-infection-status-and-reporting-of-long-covid-symptoms-in-a-population-based-birth-cohort-no-evidence-of-a-nocebo-effect
#13
JOURNAL ARTICLE
Catherine Ia Macleod-Hall, Marcus R Munafò, Maddy L Dyer
Some patients with COVID-19 develop symptoms after the acute infection, known as 'Long COVID'. We examined whether or not confirmation of COVID-19 infection status could act as a nocebo, using data from questionnaires distributed to the Avon Longitudinal Study of Parents and Children cohort. We examined associations between confirmation of COVID-19 infection status (confirmed by a positive test vs unconfirmed) and reporting of Long COVID symptoms. We explored the roles of sex and anxiety as potential moderators...
January 25, 2024: Journal of Health Psychology
https://read.qxmd.com/read/38247265/placebo-and-nocebo-responses-in-pharmacological-trials-of-tic-disorders-a-meta-analysis
#14
JOURNAL ARTICLE
Simeng Wang, Zhiyi Xiong, Yuehua Cui, Fei Fan, Si Zhang, Ru Jia, Yuchen Hu, Liang Li, Xuan Zhang, Fei Han
BACKGROUND: Clinical trials of new drugs for tic disorders (TD) often fail to yield positive results. Placebo and nocebo responses play a vital role in interpreting the outcomes of randomized controlled trials (RCTs), yet these responses in RCTs of TD remain unexplored. OBJECTIVE: The aim was to assess the magnitude of placebo and nocebo responses in RCTs of pharmacological interventions for TD and identify influencing factors. METHODS: A systematic search of the Embase, Medline, Cochrane Central Register of Controlled Trials, and PsycINFO databases was conducted...
January 21, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38234290/does-perceived-caloric-and-nutrient-intake-influence-the-acute-effect-of-beverage-consumption-on-cardiovascular-function
#15
JOURNAL ARTICLE
Ellen C McGarity-Shipley, Melanie E Vitez, Evan D Curd, Raelisa Etwaroo, Emily J Ferguson, Lindsay A Lew, Chris McGlory, Kyra E Pyke
<u>Objective:</u> To explore whether consuming the same high-fat/sugar beverage affects endothelial function differently depending on whether it is presented as 'unhealthy' vs. 'healthy'. <u>Methods:</u> Twenty-five young (21±2 years), healthy women completed three conditions: milkshake consumption (540kcal, 80g sugar, 14g fat) where correct 'unhealthy' information was given (milkshake condition), consumption of same milkshake with incorrect, 'healthy' information given (100kcal, 3g sugar, 4g fat; sham-nutrishake condition), and water consumption (control)...
January 18, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38218123/vague-sensations-about-the-background-and-consequences-of-discordance-between-actual-and-perceived-physiological-changes
#16
REVIEW
Ferenc Köteles
Empirical evidence consistently shows that discordance, also called dissociation or discrepancy, between actual physiological (mainly visceral) events and their perceived counterparts is substantial. On the one hand, we typically do not perceive actual visceral events occurring in our bodies; on the other hand, sometimes we do perceive bodily changes that do not really take place. This narrative review presents the available empirical findings on the discordance, and summarizes possible explanations that approach the phenomenon from the viewpoint of evolution, cognitive development, and predictive processing...
January 9, 2024: Clinical Psychology Review
https://read.qxmd.com/read/38215862/perceived-dehydration-impairs-endurance-cycling-performance-in-the-heat-in-active-males
#17
JOURNAL ARTICLE
Mark P Funnell, Jodie Moss, Daniel R Brown, Stephen A Mears, Lewis J James
Dehydration of >3% body mass impairs endurance performance irrespective of the individual's knowledge of their hydration status, but whether knowledge of hydration status influences performance at lower levels of dehydration is unknown. This study examined whether perception of hydration status influenced endurance performance. After familiarisation, nine active males (age 25 ± 2 y, V̇O2peak 52.5 ± 9.1 mL·kg·min-1 ) completed two randomised trials at 34°C. Trials involved an intermittent exercise preload (8 × 10 min cycling/5 min rest), followed by a 15 min all-out cycling performance test...
January 10, 2024: Physiology & Behavior
https://read.qxmd.com/read/38211773/non-adherence-to-lipid-lowering-therapy-and-strategies-to-improve-adherence
#18
REVIEW
Ashwani Mehta
Lipid lowering therapies is well-established to prevent cardiovascular events in adults with dyslipidemia and multiple risk factors. However, global clinical usage of LLT,particularly statins remains suboptimal, with adherence low rates for primary prevention and secondary prevention. Low adherence is influenced by concerns about side effects, misconceptions about benefits. Patients often discontinue statins due to perceived side effects, despite clinical trials showing no increase in symptoms compared to placebo...
January 9, 2024: Indian Heart Journal
https://read.qxmd.com/read/38211611/biosimilars-from-production-to-patient
#19
JOURNAL ARTICLE
Maria Sheridan, Matthew Massich, Nazanin Ashourian
Biologic drugs are large, complex molecules produced through biotechnology. A biosimilar is a biologic product that is highly similar to an already approved biologic (reference product), with no clinically meaningful differences in purity, safety, or efficacy; as such, a biosimilar does not need to undergo the same level of study in a clinical trial program as the original reference product. Due to the potential impact of biosimilars on patient access and health care systems, the US Food and Drug Administration introduced an abbreviated pathway for approving biosimilars (351[k]) in 2009...
January 2024: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://read.qxmd.com/read/38111283/association-between-electronic-device-use-at-bedtime-and-covid-19-vaccine-related-adverse-events-during-the-covid-19-pandemic-in-korean-adults-a-nationwide-cross-sectional-population-based-study
#20
JOURNAL ARTICLE
Kyung Wook Kang, Jiyoung Kim, Keun Tae Kim, Myeong-Kyu Kim, Yong Won Cho
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has led to heightened mood disturbances linked to increased electronic device use at bedtime (EUB). General anxiety may contribute to an increased likelihood of experiencing nocebo responses, which have been reported to be associated with COVID-19 vaccine-related adverse events (CAEs). However, no related studies have been conducted to examine this association to date. METHODS: We executed a nationwide cross-sectional study to explore these correlations during the pandemic...
December 18, 2023: Journal of Korean Medical Science
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