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https://www.readbyqxmd.com/read/28289539/contextually-aided-recovery-care-a-scientific-theory-for-innate-healing
#1
Dave Newell, Lise R Lothe, Timothy J L Raven
BACKGROUND: The chiropractic profession emerged when scientific explanations for causes of health and disease were still in infancy and the co-existence of notions such as innate healing and vitalism were perhaps admissible within such a historical context. Notwithstanding, within the scientific culture of the 21(st) Century all healthcare paradigms require evidential support which in regard these early concepts are in large part, absent. Nevertheless, a large body of emerging scientific evidence supports the existence of innate healing phenomena that may explain a plethora of clinical outcomes observed during chiropractic care...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/28277699/harnessing-the-placebo-effect-exploring-the-influence-of-physician-characteristics-on-placebo-response
#2
Lauren C Howe, J Parker Goyer, Alia J Crum
OBJECTIVE: Research on placebo/nocebo effects suggests that expectations can influence treatment outcomes, but placebo/nocebo effects are not always evident. This research demonstrates that a provider's social behavior moderates the effect of expectations on physiological outcomes. METHODS: After inducing an allergic reaction in participants through a histamine skin prick test, a health care provider administered a cream with no active ingredients and set either positive expectations (cream will reduce reaction) or negative expectations (cream will increase reaction)...
March 9, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28258765/current-insights-in-the-placebo-and-nocebo-phenomena
#3
EDITORIAL
Seetal Dodd
No abstract text is available yet for this article.
February 28, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28246492/the-effects-of-distraction-on-symptoms-during-drug-provocation-test
#4
Songul Cildag, Taskin Senturk, Gokhan Sargin
BACKGROUND: Some patients may have psychosomatic complaints due to their previous experiences during the drug hypersensitivity reaction. Worry about being hurt due to an administered drug is termed nocebo effect, which is the opposite of the placebo effect. In our study, we investigated the effect of distraction on symptoms during drug provocation test. METHODS: Our study included 112 patients who underwent DPTs for alternative purposes in our clinic. Previous hypersensitivity reactions of all the patients had objective signs...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28244667/non-coeliac-gluten-sensitivity
#5
REVIEW
Peter R Gibson, Gry I Skodje, Knut E A Lundin
Irritable bowel syndrome-like symptoms in response to wheat ingestion is common and well described, but whether the reaction is due to gluten (i.e., non-coeliac gluten sensitivity), other wheat proteins, or FODMAPs (mostly fructans) alone or in combinations has not been clearly defined. Exclusion of coeliac disease in the presence of negative serology, and normal villous architecture but increased density of intraepithelial lymphocytes on duodenal biopsies, is difficult. Furthermore, the confidence by which a positive diagnosis is made or non-coeliac gluten sensitivity is excluded by blinded placebo-controlled rechallenge with wheat protein is reduced by strong nocebo responses generally found in patients with self-reported non-coeliac gluten sensitivity...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28237673/the-placebo-and-nocebo-phenomena-their-clinical-management-and-impact-on-treatment-outcomes
#6
REVIEW
Victor Chavarria, João Vian, Círia Pereira, João Data-Franco, Brisa S Fernandes, Michael Berk, Seetal Dodd
PURPOSE: This overview focuses on placebo and nocebo effects in clinical trials and routine care. Our goal was to propose strategies to improve outcomes in clinical practice, maximizing placebo effects and reducing nocebo effects, as well as managing these phenomena in clinical trials. METHODS: A narrative literature search of PubMed was conducted (January 1980-September 2016). Systematic reviews, randomized controlled trials, observational studies, and case series that had an emphasis on placebo or nocebo effects in clinical practice were included in the qualitative synthesis...
February 22, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28210930/emotion-specific-nocebo-effects-an-fmri-study
#7
Anne Schienle, Carina Höfler, Sonja Übel, Albert Wabnegger
The neurobiological mechanisms of nocebos are still poorly understood. Thirty-eight women participated in a 'smell study' using functional magnetic resonance imaging. They were presented with an odorless stimulus (distilled water) together with the verbal suggestion that this fluid has an aversive odor which enhances disgust feelings. The nocebo was presented while the participants viewed disgusting, fear-inducing, and neutral images. Participants' affective and neuronal responses during nocebo administration were compared with those in a control condition without nocebo...
February 16, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28197000/impact-of-an-educational-module-in-antidepressant-naive-patients-prescribed-antidepressants-for-depression-pilot-proof-of-concept-randomized-controlled-trial
#8
Annie P John, Nagendra Madan Singh, Nagarajaiah, Chittaranjan Andrade
BACKGROUND: Patients are educated about their illness and its treatment at the time of diagnosis. However, little is known about how much of this education is retained and how it influences knowledge about, attitudes toward, and experiences with medication in antidepressant-naive patients with depression. METHODS: Antidepressant-naive outpatients with International Classification of Diseases-10 dysthymia or mild to moderate depression, who were advised antidepressant monotherapy, were randomized to control (n = 22) or intervention (n = 17) groups...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28177183/learning-by-experience-visceral-pain-related-neural-and-behavioral-responses-in-a-classical-conditioning-paradigm
#9
A Icenhour, F Labrenz, C Ritter, N Theysohn, M Forsting, U Bingel, S Elsenbruch
BACKGROUND: Studies investigating mechanisms underlying nocebo responses in pain have mainly focused on negative expectations induced by verbal suggestions. Herein, we addressed neural and behavioral correlates of nocebo responses induced by classical conditioning in a visceral pain model. METHODS: In two independent studies, a total of 40 healthy volunteers underwent classical conditioning, consisting of repeated pairings of one visual cue (CS(High) ) with rectal distensions of high intensity, while a second cue (CS(Low) ) was always followed by low-intensity distensions...
February 8, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28165442/antimicrobial-efficacy-of-probiotic-containing-toothpastes-an-in-vitro-evaluation
#10
Miro Klarić, Vjekoslav Mandić, Sanjin Lovrić, Martina Krešić Ćorić, Nikolina Zovko
Most people have heard of the placebo effect, while relatively few have heard of nocebo, even within the circles of medical staff. Placebo effect means positive results by treatment via pharmacological inert substances. In contrast to placebo, by nocebo effect, due to negative beliefs and expectations, opposite results are achieved. Said in a more formal manner, what a sick person expects, unfortunately, he/she most often gets. It is a fact that a high number of medical staff is still uninterested in placebo and nocebo effects, although they would benefit from them...
February 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28162564/-327-quantitative-eeg-markers-of-pain-facilitation-by-nocebo
#11
S Albu, H Linsenbardt, M Meagher
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28161116/a-review-of-the-theoretical-and-biological-understanding-of-the-nocebo-and-placebo-phenomena
#12
REVIEW
Seetal Dodd, Olivia M Dean, João Vian, Michael Berk
PURPOSE: Placebos are commonly used in experimental and patient populations and are known to influence treatment outcomes. The mechanism of action of placebos has been investigated by several researchers. This review investigates the current knowledge regarding the theoretical and biological underpinning of the nocebo and placebo phenomena. METHOD: Literature was searched using PubMed using the following keywords: nocebo, placebo, μ-opioid, dopamine, conditioning, and expectancy...
February 1, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28116120/distant-delivery-of-a-mindfulness-based-intervention-for-people-with-parkinson-s-disease-the-study-protocol-of-a-randomised-pilot-trial
#13
A Bogosian, C S Hurt, D Vasconcelos E Sa, J V Hindle, L McCracken, P Cubi-Molla
BACKGROUND: Psychological difficulties, especially depression and anxiety, are the most prevalent non-motor symptoms in Parkinson's disease. Pharmacological treatments for these conditions appear relatively ineffective in Parkinson's disease. Mindfulness courses are increasingly popular and recognised as effective for managing emotional states, and there is growing evidence for the effectiveness of mindfulness courses for people with long-term medical conditions. With this exploratory pilot trial, we want to assess the feasibility of the procedures and processes, including recruitment, most appropriate outcome measure(s), acceptability of type and number of measures, potential nocebo effects, and potential effectiveness and cost-effectiveness of a specially adapted distance-delivered mindfulness-based intervention in people affected by Parkinson's disease...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28106308/measuring-expectation-of-pain-contingent-negative-variation-in-placebo-and-nocebo-effects
#14
A Piedimonte, G Guerra, S Vighetti, E Carlino
BACKGROUND: Expectation is an important mechanism underlying placebo response. Here, we analysed expectation of placebo hypoalgesia and nocebo hyperalgesia by using, for the first time, the contingent negative variation (CNV), also known as expectancy wave. METHODS: Subjects were presented a green or red cue followed by a train of either non painful or painful electrical stimuli, and expected hypoalgesia after the green and hyperalgesia after the red cue. In experiment 1, expectation was reinforced using a conditioning procedure whereby the green and red cues were paired with non painful and painful stimuli, respectively (acquisition)...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28105896/cathechol-o-methyltransferase-val158met-polymorphism-is-associated-with-nocebo-effects-but-not-with-methotrexate-intolerance-in-patients-with-juvenile-idiopathic-arthritis
#15
B Hügle, A Scheuern, S Dollinger, N Fischer, J-P Haas
No abstract text is available yet for this article.
January 20, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28058499/-rheumatoid-arthritis
#16
REVIEW
D Aletaha, A Kerschbaumer
Therapy reduction in rheumatoid arthritis (RA) is still a challenge for physicians as well as for patients. Effective therapy with subsequent achievement of low disease activity or even remission is achievable for numerous patients using currently available treatment options. Therapy discontinuation has therefore become a hot topic and the risk of exacerbation of well-controlled RA must be weighed against the medical and economic benefits of reducing or even discontinuing therapy. This article gives a review of data regarding tapering of therapy in RA, focusing on conventional disease-modifying antirheumatic drug (DMARD) monotherapy, reduction of conventional therapy under continuing therapy with biologics and discontinuation of biologics...
February 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28054312/latent-inhibition-reduces-nocebo-nausea-even-without-deception
#17
V F Quinn, E J Livesey, B Colagiuri
BACKGROUND: Nocebo nausea is a debilitating and prevalent side effect that can develop after conditioning occurs between cues present in the treatment context and the experience of nausea. Interventions that retard conditioning may therefore be able to reduce nocebo nausea. PURPOSE: To test whether 'latent inhibition', where pre-exposing cues in the absence of an outcome retards subsequent learning about those cues, could reduce nocebo nausea in healthy adults. METHODS: We examined this possibility using a Galvanic Vestibular Stimulation (GVS) model of nausea in healthy participants, with pre-exposure to the treatment cues achieved using a placebo version of GVS...
January 4, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/27998345/stuart-justman-the-nocebo-effect-overdiagnosis-and-its-costs-new-york-palgrave-macmillan-2015-pp-%C3%A2-xi-272-hardback-79-99-isbn-%C3%A2-987-1-137-52328-0
#18
https://www.readbyqxmd.com/read/27978780/context-as-a-drug-some-consequences-of-placebo-research-for-primary-care
#19
P Lucassen, F Olesen
OBJECTIVE: On the basis of emerging research evidence, this review aims to discuss the importance of the context surrounding the doctor-patient encounter for the success of treatment. DESIGN AND SETTING: Discussion paper based on placebo-nocebo and pain studies conducted in the western world. MAIN OUTCOME MEASURES: Literature-based theory about impact of communication elements on seriousness of symptoms in clinical practice. RESULTS: The therapeutic outcome seems to be impacted by rituals around a clinical encounter and by the doctor patient communication and relation...
December 2016: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/27978485/nocebo-effect-in-refractory-partial-epilepsy-during-pre-surgical-monitoring-systematic-review-and-meta-analysis-of-placebo-controlled-clinical-trials
#20
REVIEW
Panagiotis Zis, Faiza Shafiq, Dimos-Dimitrios Mitsikostas
PURPOSE: Nocebo is very prevalent among neurological diseases resulting in low adherence and treatment outcome. We sought to examine the AEs following placebo administration in Randomized Controlled Studies (RCTs) for Epilepsy. METHOD: After a systematic Medline search for RCTs for Epilepsy pharmacological treatments, we assessed the number of discontinuations because of placebo intolerance. RESULTS: Data were extracted from 4 RCTs fulfilling our search criteria...
February 2017: Seizure: the Journal of the British Epilepsy Association
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