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Jun Sugawara, Seiko Kou, Kenichi Kokubo, Aimi Kuroda, Yoshie Hashizume, Shinji Kobayashi, Jirou Maegawa, Toshihiko Satake
INTRODUCTION: Liposuction and mesotherapy are popular treatments for fat reduction of lower face, but because these treatments are invasive, a novel non-invasive treatment with similar or better efficacy has been sought. There are various devices such as CoolSculpt, laser, RF, and HIFU that are used as non-invasive treatments for fat reduction and body contouring, but these applications have not been applied to facial fat reduction. In this study, we selected Monopolar 1-MHz RF for body contouring to be applied for fat reduction and tightening of the lower face...
April 22, 2017: Lasers in Surgery and Medicine
Ali Balevi, Pelin Ustuner, Mustafa Özdemir
INTRODUCTION: Melasma is a distressing condition for both dermatologists and patients. We evaluated the effectiveness of salicylic acid (SA) peel and vitamin C mesotherapy in the treatment of melasma. MATERIALS AND METHODS: Fifty female patients were divided into two groups. All patients were treated with 30% SA peeling every two weeks for two months. In addition, Group A was intradermally administered vitamin C on the melasma lesion at 1 cm intervals. All patients were followed up for six months, during which the recurrence rates were evaluated...
April 7, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Zekayi Kutlubay, Hilal Gokalp, Umit Ince, Burhan Engin
Mesotherapy is widely used for its lipolytic effect as an alternative procedure to surgical methods. Although many benefits of lipolytic mesotherapy has been observed, numerous side effects have also been reported. Here, we report a case of cutaneous foreign body granulomas that occurred after lipolytic mesotherapy.
March 8, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Mohamed El-Komy, Akmal Hassan, Amira Tawdy, Mohamed Solimon, Mohamed Abdel Hady
BACKGROUND: The side effects of mesotherapy for treatment of various forms of alopecia are often underreported, while scientific data for its efficacy are severely lacking. OBJECTIVE: To demonstrate the late onset side effects of mesotherapy for alopecia. METHODS: Three patients with androgenetic alopecia showed hair loss after previously uneventful mesotherapy sessions up to 1 year. RESULTS: Clinical, dermoscopic, and histopathological findings suggested an inflammatory scaring process at sites of mesotherapy injections...
February 3, 2017: Journal of Cosmetic Dermatology
Paola E Ferrara, Gianpaolo Ronconi, Rossella Viscito, Romina Pascuzzo, Eugenia Rosulescu, Concetta Ljoka, Loredana Maggi, Giorgio Ferriero, Calogero Foti
Mesotherapy, or intradermal therapy, is a therapeutic approach that is gaining popularity, but there is still a significant lack of information on its mechanisms of action or the pharmacokinetics of the therapeutic regimens. This retrospective study on 220 records compared the short-term and long-term effects of mesotherapy using a mixture of drugs versus normal saline solution in the treatment of patients with chronic spinal pain (CSP). At the end of treatment, outcome measures showed a significant improvement (P<0...
January 25, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
Ozlem Karabudak Abuaf, Hamza Yildiz, Hüseyin Baloglu, Memet Ersan Bilgili, Hasan Aktug Simsek, Bilal Dogan
BACKGROUND: Platelet-rich plasma (PRP) is an autologous concentration of human platelets contained in a small volume of plasma and has recently been shown to accelerate rejuvenate aging skin by various growth factors and cell adhesion molecules. OBJECTIVE: This study was conducted to evaluate the efficacy and safety of intradermal injection of PRP in the human facial rejuvenation. METHODS: This study was a prospective, single-center, single-dose, open-label, non-randomized controlled clinical study...
December 2016: Annals of Dermatology
Umesh Karsandas Karia, Bela Bhemabhai Padhiar, Bela Jaswantbhai Shah
BACKGROUND: Striae are linear atrophic depressions that form in areas of dermal damage in the skin. As on date, no consensus or protocol exists for the treatment of stria rubra. Topical retinoids, chemical peels, microdermabrasion, radiofrequency, photothermolysis, intense pulsed light and lasers are some of the modalities used. AIMS AND OBJECTIVE: To compare the efficacy of various therapeutic modalities in striae rubra. METHODS: This prospective cohort study comprised of a total of fifty patients from August-2012 to October-2013 in a tertiary care center in Western India, Gujarat having striae rubra...
April 2016: Journal of Cutaneous and Aesthetic Surgery
Johnson C Lee, Mark A Daniels, Malcolm Z Roth
Mesotherapy, microneedling, and chemical peels are minimally invasive techniques used to combat facial aging. Chemical peeling is one of the oldest methods of facial rejuvenation. By using different chemicals in various combinations, strengths, and application techniques, plastic surgeons can tailor a patient's treatment for optimal, safe, and consistent results. Mesotherapy and microneedling have emerged in the plastic surgery literature with increasingly complex indications. Both techniques have increased in popularity although research into efficacy and long-term results is lagging...
July 2016: Clinics in Plastic Surgery
Massimo Mammucari, Enrica Maggiori, Marzia Lazzari, Silvia Natoli
Wide variations in the types of pain and response to analgesic pharmacotherapy mean that a variety of treatment strategies are needed. One approach is mesotherapy (intradermal therapy). This consists of microinjections into the skin and is ideally suited to the management of localized pain. Advantages include increasing the duration of drug activity, reduced risk of adverse events and interactions, and possible synergy with other therapies. Mesotherapy provides general practitioners with another tool for the treatment of local pain...
June 2016: Pain and Therapy
Pierre-Antoine Deglesne, Rodrigo Arroyo, Evgeniya Ranneva, Philippe Deprez
Mesotherapy/biorevitalization with hyaluronic acid (HA) is a treatment approach currently used for skin rejuvenation. Various products with a wide range of polycomponent formulations are available on the market. Most of these formulations contain noncross-linked HA in combination with a biorevitalization cocktail, formed by various amounts of vitamins, minerals, amino acids, nucleotides, coenzymes, and antioxidants. Although ingredients are very similar among the different products, in vitro and clinical effects may vary substantially...
2016: Clinical, Cosmetic and Investigational Dermatology
A Buz, T Görgülü, A Olgun, E Kargi
BACKGROUND: Thermal burns are the leading cause of trauma worldwide. Currently, no consensus on optimal treatment of deep partial-thickness (second-degree) burns has emerged, as reflected by the wide variability in available wound-care materials. The relative efficacies of products used for treatment of partial-thickness thermal burns remain unclear. Mesotherapy features intradermal administration of various agents, depending on burn location. In the present experimental study, we explored the efficacy of mesotherapy used to treat partial-thickness thermal burns in 50 male Wistar rats divided into five groups of equal number...
December 2016: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
David Lk Chen, Joel L Cohen, Jeremy B Green
Mesotherapy is an intradermal or subcutaneous injection of therapeutic agents to induce local effects, and was pioneered in Europe during the 1950s. For the past 2 decades, there has been significant interest in the use of mesotherapy for minimally invasive local fat contouring. Based on the theorized lipolytic effects of the agent phosphatidylcholine, initial attempts involved its injection into subcutaneous tissue. With further studies, however, it became apparent that the activity attributed to phosphatidylcholine mesotherapy was due to the adipolytic effects of deoxycholate, a detergent used to solubilize phosphatidylcholine...
September 2015: Seminars in Cutaneous Medicine and Surgery
Min-Ho Kim, Hyung-Min Kim, Hyun-Ja Jeong
Recently, the placenta mesotherapy has been widely used to treat menopause. Placenta contains amino acids, peptides, minerals, and estrogen. Here, we investigated the estrogen-like osteoprotective effects of glycine (a main ingredient of placenta) in in vitro and in vivo models of menopause. We assessed the effect of glycine on MG-63 osteoblast cell line, MCF-7 estrogen-dependent cell line, and ovariectomized (OVX) mice. Glycine significantly increased the MG-63 cell proliferation in a dose-dependent manner...
March 2016: Amino Acids
Pétra Pereira de Sousa, Rossilene Conceição da Silva Cruz, Antonio Pedro Mendes Schettini, Danielle Cristine Westphal
Mycobacterium abscessus is a rapidly growing mycobacterium that has been affecting people undergoing invasive procedures, such as videosurgery and mesotherapy. This bacterium has global distribution, being found in numerous niches. The frequency of published reports of infection by rapidly growing mycobacteria associated with tattooing procedures has increased in recent years. However, in Brazil there were no case reports of M. abscessus after tattooing in the literature until now. In this paper, we describe the case of a patient with a nine-month history of lesion on a tattoo site...
September 2015: Anais Brasileiros de Dermatologia
Şule Güngör, Emek Kocatürk, İlteriş Oğuz Topal
No abstract text is available yet for this article.
April 2015: International Journal of Trichology
S Kim, J Kye, M Lee, B Park
BACKGROUND: There has been no research about the exact mechanism of transdermal drug delivery during mesotherapy. OBJECTIVE: We aimed to evaluate whether the commercial mesogun can be an appropriate technique for a transdermal drug delivery. MATERIALS AND METHODS: We injected blue ink into the polyurethane foam or pig skin with three types of mesotherapy using a commercial mesogun, or local made intradermal injector, or a manual injection of syringe...
May 2016: Skin Research and Technology
Raoul Saggini, Alexandra Di Stefano, Ira Dodaj, Laura Scarcello, Rosa Grazia Bellomo
BACKGROUND: Pes anserine bursitis strongly affects quality of life in patients with osteoarthritis. Treatment includes nonsteroidal anti-inflammatory drugs (NSAIDs), physiotherapy, and injections of corticosteroid, with highly variable responses; recovery can take 10 days to 36 months. Mesotherapy is a minimally invasive technique consisting of subcutaneous injections of bioactive substances. The goal is to modulate the pharmacokinetics of the injected substance and prolong the effects at a local level...
August 2015: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
Hana Duchková, Marta Hašková
Mesotherapy is one of the options for the treatment of androgenetic alopecia. Testing 24 women with androgenetic alopecia has demonstrated a positive effect of mesotherapy on the hair growth, hair thickness, with only insignificant increase of hair density. It is known that androgenetic alopecia represents a localized aging of hair follicles. We therefore decided to examine the different effects of mesotherapy on hair density in younger and in elderly women. In younger women mesotherapy significantly increased hair density compared with older women...
2015: Casopís Lékar̆ů C̆eských
Muhterem Polat, Hüseyin Üstün
Mesotherapy was first introduced in Europe for the treatment of localized pain. It is currently used mainly for aesthetical purposes and gradually getting widely used for body contouring, cellulite reduction, and skin rejuvenation. The reports concerning about mesotherapy is increasing in number in the literature. There are reported systemic and local side effects of mesotherapy. Panniculitis is a rare side effect of mesotherapy. In this article, we report a case of mesotherapy-induced panniculitis who responded to dapsone therapy...
2016: Cutaneous and Ocular Toxicology
Sergey Prikhnenko
Skin aging can largely be attributed to dermal fibroblast dysfunction and a decrease in their biosynthetic activity. Regardless of the underlying causes, aging fibroblasts begin to produce elements of the extracellular matrix in amounts that are insufficient to maintain the youthful appearance of skin. The goal of mesopreparations is primarily to slow down and correct changes in skin due to aging. The rationale for developing complex polycomponent mesopreparations is based on the principle that aging skin needs to be supplied with the various substrates that are key to the adequate functioning of the fibroblast...
2015: Clinical, Cosmetic and Investigational Dermatology
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