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https://www.readbyqxmd.com/read/28623247/evaluation-of-serological-indicators-and-glomerular-filtration-rate-equations-in-chinese-cancer-patients
#1
Yingna Tong, Xiaobin Liu, Mingxiu Guan, Meng Wang, Lufang Zhang, Dong Dong, Ruifang Niu, Fei Zhang, Yunli Zhou
BACKGROUND The performance of estimated glomerular filtration rate (eGFR) have been proved to vary according to the races of the target population. The eGFR equations have not been validated in the Chinese cancer population received chemotherapy. Meanwhile, serum cystatin C (CysC), urea, β2 microglobulin (β2-MG), and creatinine (SCr) were also evaluated in a cohort of Chinese cancer patients. MATERIAL AND METHODS A total of 1000 cancer patients undergoing combination chemotherapy and 108 healthy volunteers were included in this study, and their renal function parameters were evaluated...
June 17, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28622004/six-month-morbidity-and-mortality-among-icu-patients-receiving-life-sustaining-therapy-a-prospective-cohort-study
#2
Michael E Detsky, Michael O Harhay, Dominique F Bayard, Aaron M Delman, Anna E Buehler, Saida A Kent, Isabella V Ciuffetelli, Elizabeth Cooney, Nicole B Gabler, Sarah J Ratcliffe, Mark E Mikkelsen, Scott D Halpern
RATIONALE: Understanding long-term outcomes of critically ill patients may inform shared decision making in the ICU. OBJECTIVE: To quantify six-month functional outcomes of general ICU patients, and develop a multivariable model comprising factors present during the first ICU day to predict which patients will return to their baseline function 6 months later. METHODS: We conducted a prospective cohort study in three medical ICUs and two surgical ICUs in three hospitals...
June 16, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28604020/race-related-stress-and-hopelessness-in-community-based-african-american-adults-moderating-role-of-social-support
#3
Mary O Odafe, Temilola K Salami, Rheeda L Walker
OBJECTIVES: The mental health outcomes associated with racial discrimination are well documented in scientific literature. Despite strong links to mental illness, hopelessness is largely overlooked as a consequence of discrimination in empirical research. The current study examined the association of race-related stress and hopelessness in a community sample of African American adults. Utilizing a risk-resilience framework, we examined multiple dimensions of social support as plausible protective factors against the negative effects of race-related stress...
June 12, 2017: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/28571900/racial-disparities-in-health-among-nonpoor-african-americans-and-hispanics-the-role-of-acute-and-chronic-discrimination
#4
Cynthia G Colen, David M Ramey, Elizabeth C Cooksey, David R Williams
Racial disparities in health tend to be more pronounced at the upper ends of the socioeconomic (SES) spectrum. Despite having access to above average social and economic resources, nonpoor African Americans and Latinos report significantly worse health compared to nonpoor Whites. We combine data from the parents and children of the 1979 National Longitudinal Survey of Youth (NLSY79) to address two specific research aims. First, we generate longitudinal SES trajectories over a 33-year period to estimate the extent to which socioeconomic mobility is associated with exposure to discrimination (acute and chronic) across different racial/ethnic groups (nonHispanic Whites, nonHispanic Blacks, and Hispanics)...
May 6, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28570495/power-profiles-of-competitive-and-non-competitive-mountain-bikers
#5
Andrew R Novak, Kyle J M Bennett, Matthew A Pluss, Job Fransen, Mark L Watsford, Ben J Dascombe
The performance of Olympic distance cross-country mountain bikers (XCO-MTB) is affected by constraints such as erosion of track surfaces and mass start congestion which can affect race results. Standardised laboratory assessments quantify inter-seasonal and intra-seasonal cycling potential through the assessment of multiple physiological capacities. Therefore, this study examined whether the power profile assessment could discriminate between competitive XCO-MTB and non-competitive mountain bikers (NC-MTB)...
May 30, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28540604/systems-factorial-technology-provides-new-insights-on-the-other-race-effect
#6
Cheng-Ta Yang, Mario Fifić, Ting-Yun Chang, Daniel R Little
The other-race effect refers to the difficulty of discriminating between faces from ethnic and racial groups other than one's own. This effect may be caused by a slow, feature-by-feature, analytic process, whereas the discrimination of own-race faces occurs faster and more holistically. However, this distinction has received inconsistent support. To provide a critical test, we employed Systems Factorial Technology (Townsend & Nozawa in Journal of Mathematical Psychology, 39, 321-359, 1995), which is a powerful tool for analyzing the organization of mental networks underlying perceptual processes...
May 24, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28534304/an-american-crisis-the-lack-of-black-men-in-medicine
#7
Cato T Laurencin, Marsha Murray
The current state of diversity within the US medical workforce does not reflect representative numbers of the Black male population. Research data continues to reveal continuing trends in the areas of discrimination, incarceration, health disparities, and mortality with respect to Black males. The lack of increase in Black male medical school applications and matriculation contrasted by the continuing trends mentioned above illustrates that there is in fact an American crisis. We present here a call to arms, to address the need of African-American men in medicine...
May 22, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28519966/understanding-the-relationship-between-olfactory-specific-quality-of-life-objective-olfactory-loss-and-patient-factors-in-chronic-rhinosinusitis
#8
Jose L Mattos, Rodney J Schlosser, Kristina A Storck, Zachary M Soler
BACKGROUND: Chronic rhinosinusitis (CRS) significantly impacts olfaction. However, the relationship between objective olfaction and patient-reported olfactory-specific quality of life (QOL) is not well understood. Furthermore, objective olfactory testing can be time consuming, so we sought to determine if patient-reported olfactory QOL can be used as screening tool for olfactory dysfunction. METHODS: Olfactory dysfunction was evaluated in 109 patients with CRS using the Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS) and the Sniffin' Sticks Test, assessing for olfactory threshold, discrimination, identification, and overall composite scores (TDI; composite score of threshold, discrimination, and identification)...
May 18, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28498530/examining-discrimination-ethnic-racial-identity-status-and-youth-public-regard-among-black-latino-and-white-adolescents
#9
Sara Douglass, Adriana J Umaña-Taylor
How positively adolescents believe others feel about their ethnic-racial group (i.e., public regard) is an important part of their ethnic-racial identity (ERI), which is likely informed by contextual and individual factors. Using cluster analyses to generate ERI statuses among Black, Latino, and White adolescents (n = 1,378), we found that associations between peer versus adult discrimination and public regard varied across ERI status and ethnic-racial group. However, among all adolescents, an achieved ERI (i...
March 2017: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
https://www.readbyqxmd.com/read/28498074/an-analysis-from-the-quality-outcomes-database-part-1-disability-quality-of-life-and-pain-outcomes-following-lumbar-spine-surgery-predicting-likely-individual-patient-outcomes-for-shared-decision-making
#10
Matthew J McGirt, Mohamad Bydon, Kristin R Archer, Clinton J Devin, Silky Chotai, Scott L Parker, Hui Nian, Frank E Harrell, Theodore Speroff, Robert S Dittus, Sharon E Philips, Christopher I Shaffrey, Kevin T Foley, Anthony L Asher
OBJECTIVE Quality and outcomes registry platforms lie at the center of many emerging evidence-driven reform models. Specifically, clinical registry data are progressively informing health care decision-making. In this analysis, the authors used data from a national prospective outcomes registry (the Quality Outcomes Database) to develop a predictive model for 12-month postoperative pain, disability, and quality of life (QOL) in patients undergoing elective lumbar spine surgery. METHODS Included in this analysis were 7618 patients who had completed 12 months of follow-up...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28492709/differential-reporting-of-discriminatory-experiences-in-brazil-and-the-united-states
#11
Sarah Burgard, Debora de Pina Castiglione, Katherine Y Lin, Aline A Nobre, Estela M L Aquino, Alexandre C Pereira, Isabela J Martins Bensenor, Sandhi M Barreto, Dora Chor
There has been little cross-national comparison of perceived discrimination, and few studies have considered how intersectional identities shape perception of discriminatory treatment in different societies. Using data from the ELSA-Brasil, a study of Brazilian civil servants, and the Americans' Changing Lives Study, a nationally-representative sample of U.S. adults, we compare reports of lifetime discrimination among race-by-gender groups in each society. We also consider whether educational attainment explains any group differences, or if differences across groups vary by level of education...
May 8, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28492705/race-health-and-discrimination-historical-and-contemporary-perspectives-from-brazil-and-the-united-states
#12
EDITORIAL
Dóra Chor, Alexandra Minna Stern, Ricardo Ventura Santos
No abstract text is available yet for this article.
May 8, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28487137/clinical-risk-factors-alone-are-inadequate-for-predicting-significant-coronary-artery-disease
#13
Frederick K Korley, Constantine Gatsonis, Bradley S Snyder, Richard T George, Thura Abd, Stefan L Zimmerman, Harold I Litt, Judd E Hollander
OBJECTIVE: We sought to derive and validate a model for identifying suspected ACS patients harboring undiagnosed significant coronary artery disease (CAD). METHODS: This was a secondary analysis of data from a randomized control trial (RCT). Patients randomized to the CTA arm of an RCT examining a CTA-based strategy for ruling-out acute coronary syndrome (ACS) constitute the derivation cohort, which was randomly divided into a training dataset (2/3, used for model derivation) and a test dataset (1/3, used for internal validation (IV))...
July 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28482209/socioeconomic-status-discrimination-and-c-reactive-protein-in-african-american-and-white-adults
#14
Miriam E Van Dyke, Viola Vaccarino, Sandra B Dunbar, Priscilla Pemu, Gary H Gibbons, Arshed A Quyyumi, Tené T Lewis
OBJECTIVES: We examined the association between socioeconomic status (SES) discrimination and C-reactive protein (CRP) in a biracial cohort of middle-aged adults using an intersectionality framework. METHODS: Participants were 401 African-American and White adults from a population-based cohort in the Southeastern United States. SES discrimination was self-reported with a modified Experiences of Discrimination Scale, and CRP levels were assayed from blood samples...
April 23, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28481976/electronically-available-comorbidities-should-be-used-in-surgical-site-infection-risk-adjustment
#15
Sarah S Jackson, Surbhi Leekha, Laurence S Magder, Lisa Pineles, Deverick J Anderson, William E Trick, Keith F Woeltje, Keith S Kaye, Timothy J Lowe, Anthony D Harris
Background: Healthcare-associated infections such as surgical site infections (SSI) are used by Centers for Medicare and Medicaid Services (CMS) as pay-for-performance metrics. Risk adjustment allows a fairer comparison of SSI rates across hospitals. Until 2016, Centers for Disease Control and Prevention (CDC) risk adjustment models for pay-for-performance SSI did not adjust for patient comorbidities. New 2016 CDC models only adjust for body mass index and diabetes. Methods: We performed a multicenter retrospective cohort study of patients undergoing surgical procedures at 28 US hospitals...
May 6, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28479094/integrating-genotypes-in-the-same-tt2r2-score-for-the-prediction-of-anticoagulation-control-in-chinese-patients-with-atrial-fibrillation-on-warfarin
#16
Jia Liu, Nina Wang, Liuan Qin, Jun Liu, Shaozhi Xi, Xuyun Wang, Xiaoqi Li, Yuxiao Zhang, Tong Yin
INTRODUCTION: The SAMe-TT2R2 score has been proposed to predict whether patients with atrial fibrillation (AF) would be well anti-coagulated with warfarin or not. However, it might over-estimate the number of patients under suboptimal warfarin treatment in non-Caucasians. This study was designed to modify the SAMe-TT2R2 score with genotypes and validate it in Chinese AF patients treated with warfarin. MATERIAL AND METHODS: Consented Chinese-Han patients (n=510) with AF under the treatment of warfarin for at least 3months were randomly divided into a derivation (n=310) and a validation cohort (n=200)...
April 29, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28445210/perceived-discrimination-and-longitudinal-change-in-kidney-function-among-urban-adults
#17
May A Beydoun, Angedith Poggi-Burke, Alan B Zonderman, Ola S Rostant, Michele K Evans, Deidra C Crews
OBJECTIVE: Perceived discrimination has been associated with psychosocial distress and adverse health outcomes. We examined associations of perceived discrimination measures with changes in kidney function in a prospective cohort study, the Healthy Aging in Neighborhoods of Diversity Across the LifeSpan. METHODS: Our study included 1,620 participants with preserved baseline kidney function (estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73m) (662 Whites and 958 African-Americans (AA), aged 30-64 years)...
April 26, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28426694/prediction-of-atherosclerotic-cardiovascular-disease-mortality-in-a-nationally-representative-cohort-using-a-set-of-risk-factors-from-pooled-cohort-risk-equations
#18
Zefeng Zhang, Cathleen Gillespie, Barbara Bowman, Quanhe Yang
The American College of Cardiology/American Heart Association developed Pooled Cohort equations to estimate atherosclerotic cardiovascular disease (ASCVD) risk. It is unclear how well the equations predict ASCVD mortality in a nationally representative cohort. We used the National Health and Nutrition Examination Survey (NHANES) 1988-1994 and Linked Mortality through 2006 (n = 6,644). Among participants aged 40-79 years without ASCVD at baseline, we used Cox proportional hazard models to estimate the 10-year probability of ASCVD death by sex and race-ethnicity (non-Hispanic white (NHW), non-Hispanic black (NHB) and Mexican American (MA))...
2017: PloS One
https://www.readbyqxmd.com/read/28425739/sleep-duration-partially-accounts-for-race-differences-in-diurnal-cortisol-dynamics
#19
Laurel M Peterson, Karissa G Miller, Patricia M Wong, Barbara P Anderson, Thomas W Kamarck, Karen A Matthews, Clemens Kirschbaum, Stephen B Manuck
OBJECTIVE: Emerging research demonstrates race differences in diurnal cortisol slope, an indicator of hypothalamic-pituitary-adrenocortical (HPA)-axis functioning associated with morbidity and mortality, with African Americans showing flatter diurnal slopes than their White counterparts. Sleep characteristics are associated with both race and with HPA-axis functioning. The present report examines whether sleep duration may account for race differences in cortisol dynamics. METHOD: Participants were 424 employed African American and White adults (mean age = 42...
May 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28414495/racial-discrimination-racial-identity-and-impostor-phenomenon-a-profile-approach
#20
Donte L Bernard, Lori S Hoggard, Enrique W Neblett
OBJECTIVES: This study examined the association between racial discrimination and the impostor phenomenon (IP) and the moderating influence of racial identity on this relationship. METHOD: One hundred fifty-seven African American college students (68% female; mean age = 18.63) completed measures of racial discrimination, racial identity, and IP during 2 waves of data collection. RESULTS: Utilizing latent profile analyses, 4 patterns of racial identity were identified: Undifferentiated, Multiculturalist, Race-Focused, and Humanist...
April 17, 2017: Cultural Diversity & Ethnic Minority Psychology
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