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Aortic coarctation

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https://www.readbyqxmd.com/read/29667078/impact-of-different-coarctation-therapies-on-aortic-stiffness-phase-contrast-mri-study
#1
Michal Schäfer, Gareth J Morgan, Max B Mitchell, Michael Ross, Alex J Barker, Kendall S Hunter, Brian Fonseca, Michael DiMaria, Daniel Vargas, D Dunbar Ivy, Neil Wilson, Lorna P Browne
Coarctation of the aorta has been associated with increased thoracic aortic stiffness in adolescents and young adults. However, the effects of different therapeutic strategies on aortic stiffness in a young population is unknown. This study aimed to non-invasively assess aortic stiffness between different repair or intervention strategies in patients with coarctation of the aorta. Forty-nine coarctation patients who underwent either surgery (n = 26), balloon angioplasty (n = 14), or stent implantation (n = 12), and 26 age- and size-matched normotensive healthy controls underwent evaluation of thoracic aortic stiffness and flow hemodynamics via phase-contrast cardiac magnetic resonance...
April 17, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29664433/case-image-treatment-of-aortic-coarctation-saccular-thoracic-aortic-aneurysm-and-corresponding-feeding-collateral-vessel-with-a-fully-percutaneous-endovascular-approach
#2
Ertan Vuruşkan, Gökhan Altunbaş, Fatma Yılmaz Coşkun, Osman Başpınar, Murat Sucu
No abstract text is available yet for this article.
April 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29622358/arterial-reconstructions-for-pediatric-splanchnic-artery-occlusive-disease
#3
Dawn M Coleman, Jonathan L Eliason, James C Stanley
OBJECTIVE: Pediatric splanchnic arterial occlusive disease is uncommon and a rare cause of clinically relevant intestinal ischemia. This study was undertaken to better define the clinical manifestations and appropriate treatment of celiac artery (CA) and superior mesenteric artery (SMA) occlusive disease in children. METHODS: Clinical courses of 30 consecutive children undergoing operations for splanchnic arterial occlusive disease at the University of Michigan from 1992 to 2017 were retrospectively analyzed...
April 2, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29614911/stenting-coarctation-of-the-fifth-aortic-arch-a-safe-and-attractive-therapeutic-alternative-to-surgery
#4
Marc Figueras-Coll, Anna Sabaté-Rotés, Pedro Betrián-Blasco, Pedro Ortuño-Muro
"Persistence of the fifth aortic arch" is a rare congenital abnormal vessel arising from the distal ascending aorta connecting with the systemic or pulmonary circulation. We report a case of a type A interruption of the aortic arch and a coarctation of the fifth aortic arch, which connected the ascending with the descending aorta. No cardiac surgery was required because a covered stent was successfully implanted in the fifth aortic arch when the patient was 4 years old. A chromosome 9 q arm duplication of uncertain significance was also found, an anomaly never described before in this clinical context...
January 1, 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29606489/-the-begraft-bentley-%C3%A2-stent-for-treatment-of-aortic-coarctation
#5
José Carlos Buenfil-Medina, María Guadalupe Jiménez-Carbajal, Rogerio Santiago-Herrera, Claudia Paola Fernández-Luna
No abstract text is available yet for this article.
March 29, 2018: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/29590334/a-rare-missense-mutation-in-myh6-associates-with-non-syndromic-coarctation-of-the-aorta
#6
Thorsteinn Bjornsson, Rosa B Thorolfsdottir, Gardar Sveinbjornsson, Patrick Sulem, Gudmundur L Norddahl, Anna Helgadottir, Solveig Gretarsdottir, Audur Magnusdottir, Ragnar Danielsen, Emil L Sigurdsson, Berglind Adalsteinsdottir, Sverrir I Gunnarsson, Ingileif Jonsdottir, David O Arnar, Hrodmar Helgason, Tomas Gudbjartsson, Daniel F Gudbjartsson, Unnur Thorsteinsdottir, Hilma Holm, Kari Stefansson
Aims: Coarctation of the aorta (CoA) accounts for 4-8% of congenital heart defects (CHDs) and confers substantial morbidity despite treatment. It is increasingly recognized as a highly heritable condition. The aim of the study was to search for sequence variants that affect the risk of CoA. Methods and results: We performed a genome-wide association study of CoA among Icelanders (120 cases and 355 166 controls) based on imputed variants identified through whole-genome sequencing...
March 24, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29578201/use-of-covered-stents-in-simultaneous-management-of-coarctation-of-the-aorta-and-patent-ductus-arteriosus
#7
Emine Hekim Yılmaz, Mustafa Orhan Bulut, Mehmet Küçük, İlker Kemal Yücel, Abdullah Erdem, Ahmet Çelebi
OBJECTIVE: To report clinical and procedural characteristics of twelve patients who received a covered stent for the treatment of aortic coarctation and concurrent patent ductus arteriosus (PDA). METHODS: A single center database was retrospectively evaluated to obtain data of patients with combined aortic coarctation and PDA. We selected patients in whom a covered stent was used for the treatment of both pathologies. The stent length was chosen so as to cover the entire length of the lesion from healthy to healthy tissue and also cover the ampulla of PDA...
March 21, 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29562426/-efficacy-of-coarctation-resection-and-aortoplasty-with-autologous-pulmonary-artery-patch-strategy-for-treating-coarctation-of-the-aorta-combined-with-hypoplastic-aortic-arch-in-infants
#8
Z L Ma, J Yan, S J Li, Z D Hua, F X Yan, X Wang, Q Wang
Objective: To investigate the outcomes of coarctation resection and aortoplasty with autologous pulmonary artery patch for treating coarctation of the aorta combined with hypoplastic aortic arch in infants. Methods: Clinical data of 21 infants with coarctation of the aorta and hypoplastic aortic arch, who underwent coarctation resection and aortoplasty with autologous pulmonary artery patch in Fuwai hospital from January 2009 to June 2016 were retrospectively analyzed. The age of the patients was 4 (2, 5) months,and the body weight of the patients was (5...
March 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29550016/primary-coronary-stent-implantation-is-a-feasible-bridging-therapy-to-surgery-in-very-low-birth-weight-infants-with-critical-aortic-coarctation
#9
Raymond Stegeman, Johannes M P J Breur, Jörg Heuser, Nicolaas J G Jansen, Willem B de Vries, Daniel C Vijlbrief, Mirella M C Molenschot, Felix Haas, Gregor J Krings
BACKGROUND: Surgical treatment of critical aortic coarctation (CoA) is difficult in very low birth weight (VLBW) infants ≤1500 g and preferably postponed until 3 kg with prostaglandins (PGE). OBJECTIVES: To investigate the procedure and outcome of primary coronary stent implantation as bridging therapy to surgery in VLBW infants with CoA. METHODS: Retrospective evaluation of primary CoA stenting in VLBW infants from 2010 to 2015. RESULTS: Five VLBW infants with a median gestational age of 29 weeks (27-32) underwent primary CoA stenting...
March 8, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29549184/congenital-left-sided-heart-obstruction
#10
REVIEW
Michelle Carr, Stephanie Curtis, Jan Marek
Congenital obstruction of the left ventricular outflow tract remains a significant problem and multi-level obstruction can often co-exist. Obstruction can take several morphological forms and may involve the subvalvar, valvar or supravalvar portion of the aortic valve complex. Congenital valvar stenosis presenting in the neonatal period represents a spectrum of disorders ranging from the hypoplastic left heart syndrome to almost normal hearts. Treatment options vary dependent on the severity of the left ventricular outflow tract obstruction (LVOTO) and the variable degree of left ventricular hypoplasia as well as the associated lesions such as arch hypoplasia and coarctation...
March 16, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29531485/surgical-management-of-aortic-coarctation-from-infant-to-adult
#11
Ugur Kaya, Abdurrahim Colak, Necip Becit, Munacettin Ceviz, Hikmet Kocak
Objective: In the present study, we aimed to retrospectively investigate the early and late results of different surgical treatment techniques applied in different age groups with coarctation of the aorta (CoA). Materials and Methods: Between January 2007 and February 2017, 26 patients (12 males, 14 females; mean age: 12.2±12.4 years; range: 29 days-34 years) who underwent surgery with the diagnosis of CoA were evaluated. Overall, 11 of these patients (42.3%) were in the infantile period, whereas 15 patients (57...
February 2018: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29528405/stent-grafting-simulation-using-a-three-dimensional-printed-model-for-extensive-aortic-arch-repair-combined-with-coarctation
#12
Takayuki Shijo, Takashi Shirakawa, Masao Yoshitatsu, Keiji Iwata
Stent grafting for complex aortic anatomy remains a challenge. In particular, stent graft collapse (i.e. infolding) is possible when an excessive oversized device is needed. We describe a case of preoperative stent grafting simulation using a three-dimensional (3D) printed model for extensive aortic arch repair in a 69-year-old woman with multiple aneurysms combined with coarctation. The patient was scheduled to undergo staged hybrid repair. A stent graft larger than 28 mm in diameter was needed to deploy into a coarctation of 15 mm in diameter during the 2nd stage of the operation...
March 8, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29516632/volumetric-segmentation-free-method-for-rapid-visualization-of-vascular-wall-shear-stress-using-4d-flow-mri
#13
Evan M Masutani, Francisco Contijoch, Espoir Kyubwa, Joseph Cheng, Marcus T Alley, Shreyas Vasanawala, Albert Hsiao
PURPOSE: To develop a rapid segmentation-free method to visualize and compute wall shear stress (WSS) throughout the aorta using 4D Flow MRI data. WSS is the drag force-per-area the vessel endothelium exerts on luminal blood; abnormal levels of WSS are associated with cardiovascular pathologies. Previous methods for computing WSS are bottlenecked by labor-intensive manual segmentation of vessel boundaries. A rapid automated segmentation-free method for computing WSS is presented. THEORY AND METHODS: Shear stress is the dot-product of the viscous stress tensor and the inward normal vector...
March 7, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29510943/laryngeal-ultrasound-detects-a-high-incidence-of-vocal-cord-paresis-after-aortic-arch-repair-in-neonates-and-young-children
#14
Melissa G Y Lee, Johnny Millar, Elizabeth Rose, Aleesha Jones, Dora Wood, Taryn L Luitingh, Diana Zannino, Johann Brink, Igor E Konstantinov, Christian P Brizard, Yves d'Udekem
OBJECTIVES: To determine the incidence of vocal cord paresis (VCP) after neonatal aortic arch repair/Norwood-type procedure, and the effectiveness of noninvasive laryngeal ultrasound in detecting VCP compared with gold standard invasive nasoendoscopy. METHODS: Fifty-two patients who underwent an arch repair (39 of 52; 75%) or Norwood-type procedure (13 of 52; 25%) via sternotomy between April 1, 2015, and April 30, 2017 underwent laryngeal ultrasound (50 of 52; 96%) and/or flexible fiber optic nasoendoscopy (39 of 52; 75%) at 48 to 72 hours after endotracheal extubation...
February 9, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29486816/spontaneous-regression-of-severe-aortic-coarctation-in-trisomy-18
#15
Shun Matsumura, Satoshi Masutani, Hideaki Senzaki
Spontaneous regression of severe aortic coarctation with ductus dependency has not been reported. We experienced a case of trisomy 18 with spontaneous regression of severe aortic coarctation complicated by ventricular septal defect and patent ductus arteriosus. The aortic isthmus diameter was 1.2 mm at birth. After 5 months, it increased to 4.5 mm, and the shape of the isthmus was fully normalised.
February 28, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29483464/-surgical-experience-of-distal-aortic-arch-aneurysm-suspected-to-be-associated-with-pre-existing-coarctation-of-the-aorta
#16
Yoshinori Kuroda, Tetsuro Uchida, Azumi Hamasaki, Atsushi Yamashita, Masahiro Mizumoto, Jun Hayashi, Ai Ishizawa, Kentaro Akabane, Mitsuaki Sadahiro
A 45 year-old-man who had undergone ventricular septal defect repair during childhood presented with hoarseness. He was diagnosed as having a distal aortic arch aneurysm by using computed tomography, and was referred to our hospital for surgical treatment. The operation was performed via a 4th intercostal thoracotomy in the right lateral position. The aortic aneurysm occupied the upper pleural cavity. The aortic arch was pressed up by the aortic aneurysm, so visual identification and clamping of the proximal aorta and the left subclavian artery were extremely difficult...
February 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29481306/platelet-derived-microparticles-promote-endothelial-cell-proliferation-in-hypertension-via-mir-142-3p
#17
Han Bao, Yuan-Xiu Chen, Kai Huang, Fei Zhuang, Min Bao, Yue Han, Xiao-Hu Chen, Qian Shi, Qing-Ping Yao, Ying-Xin Qi
Endothelial cells (ECs) are located at the interface between flowing blood and the vessel wall, and abnormal EC proliferation induced by pathologic environments plays an important role in vascular remodeling in hypertensive conditions. Exchanges of information between blood components and ECs are important for EC function. Hence, the present study sought to determine how platelets induce EC dysfunction under hypertensive conditions. EC proliferation was increased in renal hypertensive rats established by abdominal aortic coarctation compared with control rats and that elevated thrombin in plasma promoted platelet activation, which may induce the release of platelet-derived microparticles (PMPs)...
February 26, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29459614/a-case-of-severe-coarctation-of-aorta-associated-with-bicuspid-aortic-valve-managed-surgically
#18
M N Hasan, M K Ahmed, M M Rahman, T Parvin, M B Rashid, F I Khaled, S S Shakil
Coarctation of the aorta is a congenital cardiac malformation that can go undiagnosed until old age with only hypertension as a marker of its presence because clinical signs can be subtle and overlooked if a complete physical exam is not performed. Long-term survival is exceptional in patients with untreated aortic coarctation. In this case report, we present a late diagnosis of aortic coarctation in a 45-year-old male. Our patient was relatively asymptomatic until he presented with exertional dyspnea and fatigue in his fourth decade of life in Bangabandhu Sheikh Mujib Medical University (BSMMU), on the month of August, 2016...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29459569/selection-of-a-surgical-treatment-approach-for-aortic-coarctation-in-adolescents-and-adults
#19
Eisaku Nakamura, Kunihide Nakamura, Koji Furukawa, Hirohito Ishii, Katsuya Kawagoe
PURPOSE: Coarctation of the aorta (CoA) in adolescents and adults is relatively rare. Several operative techniques for CoA in adolescents and adults have been reported, but there is still no consensus. This study aims to highlight the use of individual patient characteristics to select optimal treatment strategies for CoA in adolescents and adults. METHODS: Surgical repair of CoA was performed in five patients (mean age: 34 ± 14 years, range: 13-58 years). All patients had primary CoA, and one had aneurysm above the CoA...
February 16, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29440839/discontinuity-of-the-arch-beyond-the-origin-of-the-left-subclavian-artery-in-an-adult-interruption-or-coarctation
#20
Pradeep Vaideeswar, Supreet Marathe, Saranya Singaravel, Robert H Anderson
Congenital aortic anomalies are uncommon causes of secondary hypertension and are seldom suspected in the adult age group. We present a case of aortic interruption unexpectedly diagnosed on autopsy in a 38-year-old male who presented with cardiovascular collapse. Apart from interruption, a finding unique to our case was aneurysmal dilation of the proximal descending aorta just before the obstruction with thrombosis. We also attempt to review the literature for interrupted aortic arch in adults and clarify the nomenclature of interruption versus coarctation...
January 2018: Annals of Pediatric Cardiology
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