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Skin and soft tissue infection

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https://www.readbyqxmd.com/read/29932092/madura-foot-an-imported-case-of-a-non-common-diagnosis
#1
Teresa Fasciana, Claudia Colomba, Adriana Cervo, Paola Di Carlo, Francesco Scarlata, Chiara Mascarella, Anna Giammanco, Antonio Cascio
Mycetoma (or "madura foot") is characterized by deformation, cutaneous lesions, infection of tissues extending from the cutaneous layer to the underlying fascia, and an indolent course. A number of fungal or bacterial agents that are introduced through traumatic inoculation can be responsible for the disease, but Actinomadura madurae is among the most common agents of mycetoma occurring worldwide. We report a case of madura foot caused by A. madurae in an immunocompetent young Somali man who was admitted with a diagnosis of skin and soft tissue infection of the left foot with osteomyelitis...
June 1, 2018: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/29931268/placenta-to-the-rescue-limb-salvage-using-dehydrated-human-amnion-chorion-membrane
#2
Victoria Schlanser, Andrew Dennis, Katarina Ivkovic, Kimberly Joseph, Matthew Kaminsky, Thomas Messer, Stathis Poulakidas, Frederic Starr, Faran Bokhari
Reconstruction of skin and soft tissue wounds can pose a unique surgical challenge. This is especially true for cases of exposed bone and tendon where soft tissue loss is extensive and opportunities for tissue advancement or rotation are limited. A clinical case is presented describing an experience with dehydrated human amnion/chorion membrane (dHACM, EpiFix®/AmnioFix®, MiMedx Group, Marietta, GA) graft to obtain granulation over an open fracture with desiccated bone. The 22-year-old female trauma patient presented with high-grade bilateral lower extremity soft tissue loss after being run over and dragged by a semitruck...
December 5, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29930012/maternal-weight-and-infections-in-early-childhood-a-cohort-study
#3
Samuel Videholm, Sven-Arne Silfverdal, Georges Reniers
OBJECTIVE: The aim of this study was to examine this association between maternal weight during pregnancy and the incidence of hospitalisations for infectious diseases during early childhood. DESIGN: A population-based cohort study. SETTING: A national cohort was created by combining data from the Swedish Medical Birth Register, the National Inpatient Register, the Cause of Death Register, the Total Population Register and the Longitudinal integration database for health insurance and labour market studies...
June 21, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29924201/bilateral-periorbital-necrotizing-fasciitis-case-report
#4
Fabio Henrique Luiz Leonardo, Mariana Anabuki, Allan Christian Pieroni Gonçalves
Necrotizing fasciitis is a severe infection of the subcutaneous tissue characterized by necrosis of the superficial fascia and overlying skin and is usually associated with previous trauma and comorbidities. Periorbital necrotizing fasciitis is rare and commonly causes visual loss and soft tissue defects. A better prognosis relies critically on early diagnosis, prompt medical treatment, and timely surgical intervention. We describe a rare case of periorbital necrotizing fasciitis in the absence of an inciting event...
June 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/29916973/adjunctive-use-of-the-dermocartilaginous-ligament-for-dorsal-irregularities-in-primary-rhinoplasty
#5
Orhan Ozturan, Alper Yenigun, Selahattin Tugrul, Fadlullah Aksoy
Nasal dorsal irregularity is a common postrhinoplasty complication in spite of meticulous smoothing. Utilization of the dermocartilaginous ligament in 2 different fashions for different purposes was described before. A novel utilization of the dermocartilaginous ligament as a flattened and pedicled flap from the cephalic attachment for nasal dorsal irregularities was presented in this article. This surgical technique was applied in 11 cases. Eight of them had thin skin, 2 had skin with medium thickness, and 1 had thick skin...
June 18, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29915657/daptomycin-associated-eosinophilic-pneumonia-case-report-and-differential-diagnoses
#6
Sijan Basnet, Niranjan Tachamo, Rashmi Dhital, Biswaraj Tharu
Daptomycin is a bactericidal antibiotic approved for treatment of gram-positive skin and soft tissue infections. We present a case of an 89-year-old man who presented with fever, shortness of breath and nonproductive cough on week 4 of starting daptomycin for infective endocarditis. Computerized tomography scan showed bilateral interstitial infiltrates predominantly affecting the lower lobes. He also had peripheral eosinophilia of 6%. He was diagnosed with eosinophilic pneumonia secondary to daptomycin use...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29914924/intravenous-cefazolin-plus-oral-probenecid-versus-oral-cephalexin-for-the-treatment-of-skin-and-soft-tissue-infections-a-double-blind-non-inferiority-randomised-controlled-trial
#7
Dawn Dalen, Amy Fry, Samuel G Campbell, Jeffrey Eppler, Peter J Zed
OBJECTIVE: The purpose of our study was to determine if cephalexin 500 mg orally four times daily was non-inferior to cefazolin 2 g intravenously daily plus probenecid 1 g orally daily in the management of patients with uncomplicated mild-moderate skin and soft tissue infection (SSTI) presenting to the ED. METHODS: This was a prospective, multicentre, double dummy-blind, randomised controlled non-inferiority trial conducted at two tertiary care teaching hospitals in Canada...
June 18, 2018: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29912846/dissemination-of-the-methicillin-resistance-staphylococcus-aureus-pediatric-clone-st5-t002-iv-pvl-as-a-major-cause-of-community-associated-staphylococcal-infections-in-bedouin-children-southern-israel
#8
Assaf Rokney, Moti Baum, Shalom Ben-Shimol, Orli Sagi, Einav Anuka, Vered Agmon, David Greenberg, Lea Valinsky, Dana Danino
INTRODUCTION: Pediatric community associated methicillin resistant Staphylococcus aureus (CA-MRSA) infections are emerging worldwide. High CA-MRSA carriage rates were previously described in healthy Bedouin children. We assessed demographic, clinical and molecular characteristics of pediatric MRSA infections in southern Israel. METHODS: The Soroka University Medical Center laboratory serves the entire population of southern Israel, divided into two ethnic groups, Bedouins and Jews...
June 15, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29912305/decreasing-incidence-of-skin-and-soft-tissue-infections-at-86-u-s-emergency-departments-2009-2014
#9
Ethan Morgan, Sam Hohmann, Jessica Ridgeway, Robert Daum, Michael Z David
Introduction: The incidence of skin and soft tissue infections (SSTIs), for which HIV is a significant risk factor, in United States emergency departments (EDs) increased dramatically after 2000 with the emergence of CA-MRSA. Few studies have examined SSTI incidence among U.S. HIV-infected and non-HIV-infected patients after 2010. Methods: Data were obtained for patient encounters at all academic medical center EDs affiliated with the Vizient clinical data warehouse who had an SSTI-associated ICD-9 code between January 1, 2009 and December 31, 2014...
June 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29907621/heroin-use-is-associated-with-aa-type-kidney-amyloidosis-in-the-pacific-northwest
#10
Arjun Sharma, Priyanka Govindan, Mirna Toukatly, Jack Healy, Connor Henry, Steve Senter, Behzad Najafian, Bryan Kestenbaum
BACKGROUND AND OBJECTIVES: AA-type kidney amyloidosis is classically associated with chronic autoimmune or inflammatory disorders. However, some urban centers have reported a high prevalence of injection drug use among patients with kidney AA amyloidosis. Previous reports lack control groups to quantify associations and most predate the opioid epidemic in the United States. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a case-control study of 38 patients with biopsy-confirmed kidney AA amyloidosis and 72 matched control individuals without this condition from two large hospital systems in Seattle, Washington...
June 15, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29904969/mucormycotic-parotitis-and-otitis-causing-facial-nerve-palsy-in-a-diabetic-patient
#11
Debasis Gochhait, Arun Alexender, Priyadarshini Dehuri, Vidhyalakshmi Rangarajan, Sajini Elizabeth Jacob, Neelaiah Siddaraju
Isolated invasive Mucormycosis of the parotid gland is rarely reported in the literature (1). Mucormycosis most commonly manifests as rhino-oculocerebral and pulmonary infections in the patients with altered immunity (uncontrolled Diabetes mellitus, recipients of immunosupressive therapy and underlying hematological malignancies) (2). Rarely, it causes infection in the immunocompetent individuals (3) with the involvement of unusual sites like gastrointestinal tract, ear, soft tissue and skin (4, 5). This article is protected by copyright...
June 15, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29900086/mass-compression-from-recurrent-lymphoma-mimicking-lower-extremity-cellulitis
#12
David G Li, Katherine M Krajewski, Arash Mostaghimi
Cellulitis is a common skin and soft tissue infection with substantial misdiagnosis rates due to its nonspecific clinical characteristics. In this report, we present a patient with recurrent metastatic diffuse large B-cell lymphoma (DLBCL) masquerading as a unilateral lower extremity cellulitis. A 62-year-old man with a history of DLBCL, in remission for two years, presented with a two-week history of swelling and erythema of the right thigh and leg. Despite treatment with clindamycin and cephalexin, the redness and swelling continued to progress...
April 12, 2018: Curēus
https://www.readbyqxmd.com/read/29899987/-streptococcus-pyogenes-and-invasive-central-nervous-system-infection
#13
Ekamjeet Randhawa, John Woytanowski, Kedesha Sibliss, Ian Sheffer
Streptococcus pyogenes is a Gram-positive beta-hemolytic bacteria, also known as group A streptococci, that causes a range of infections. The most common presentation is acute pharyngitis; however, it is also implicated in skin and soft tissue infections, and less commonly bacteremia, osteomyelitis, pneumonia, otitis media and sinusitis. Group A streptococci infections of the central nervous system are exceedingly rare in the antibiotic era. The mechanism of infection is typically contiguous spread from existing infection or via direct inoculation...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29897142/clinical-and-microbiological-properties-of-staphylococcus-lugdunensis-skin-infections
#14
Hiba Zaaroura, Yuval Geffen, Reuven Bergman, Emily Avitan-Hersh
Staphylococcus lugdunensis is an emerging pathogen in skin and soft tissue infections that was previously considered a commensal. The aim of this study was to elucidate the characteristics of skin infections by S. lugdunensis and its appropriate management, in a tertiary referral medical center. The clinical files, bacterial cultures and histopathology reports of all S. lugdunensis isolates from skin infections over a period of 8 years (September 2009-September 2017) were reviewed. S. lugdunensis was isolated from 29 patients with skin infections, aged 7-89 years (mean 33...
June 13, 2018: Journal of Dermatology
https://www.readbyqxmd.com/read/29896026/results-of-ring-ilizarov-fixator-in-high-energy-schatzker-type-vi-fractures-of-proximal-tibia
#15
Ujjwal Kanti Debnath, Dipak Kumar Jha, Prasanta Kumar Pujari
Background: High-energy fractures of proximal tibia (Schatzker VI) are associated with severe articular depression, separation of both condyles, diaphyseal comminution & dissociation with loss of integrity of the soft-tissue envelope. Complications of plating are well known since last 50years in these difficult fractures. An alternative method was proposed by Ilizarov (ring fixator) and was adopted for the treatment of these complex injuries. Aim of study: To analyse the results of patients who had ring fixator for the management of high-energy fractures (Schatzker VI) of the proximal tibia...
April 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29893658/a-retrospective-analysis-of-adverse-events-among-patients-receiving-daptomycin-versus-vancomycin-during-outpatient-parenteral-antimicrobial-therapy
#16
Gregory M Schrank, Sharon B Wright, Westyn Branch-Elliman, Mary T LaSalvia
OBJECTIVE: Outpatient parenteral antimicrobial therapy (OPAT) is a safe and effective alternative to prolonged inpatient stays for patients requiring long-term intravenous antimicrobials, but antimicrobial-associated adverse events remain a significant challenge. Thus, we sought to measure the association between choice of antimicrobial agent (vancomycin vs daptomycin) and incidence of adverse drug events (ADEs). METHODS: Patients receiving OPAT treatment with vancomycin or daptomycin for skin and soft-tissue infections, bone and joint infections, endocarditis, and bacteremia or endovascular infections during the period from July 1, 2013, through September 30, 2016, were included...
June 12, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29888714/the-use-of-sural-island-musculo-fasciocutaneous-flap-in-the-management-of-chronic-osteomyelitis-of-the-tibia
#17
K O Opara, I C Nwagbara
Background: : The management of soft-tissue defects following surgery for chronic osteomyelitis of the tibia is challenging. It often requires complex reconstructive procedures, especially when the distal third of the tibia is involved. We present a relatively simple method of addressing these defects. Aim: : This study aims to report our experience with the use of the sural Island musculo fasciocutaneous flap in the management of osteomyelitis of the tibia. Materials and Methods: : Consecutive patients with osteomyelitis of the tibia requiring soft-tissue cover were managed using the sural Island musculo fasciocutaneous flap, and the outcome was analyzed...
June 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29886150/management-of-septic-non-union-of-the-tibia-by-the-induced-membrane-technique-what-factors-could-improve-results
#18
Renaud Siboni, Etienne Joseph, Laurent Blasco, Coralie Barbe, Odile Bajolet, Saïdou Diallo, Xavier Ohl
INTRODUCTION: Management of septic non-union of the tibia requires debridement and excision of all infected bone and soft tissues. Various surgical techniques have been described to fill the bone defect. The "Induced Membrane" technique, described by A.C Masquelet in 1986, is a two-step procedure using a PMMA cement spacer around which an induced membrane develops, to be used in the second step as a bone graft holder for the bone graft. The purpose of this study was to assess our clinical and radiological results with this technique in a series managed in our department...
June 7, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29882122/coagulase-negative-staphylococcus-skin-and-soft-tissue-infections
#19
REVIEW
Nicola E Natsis, Philip R Cohen
Coagulase-negative staphylococcus organisms may be normal flora of human skin, however these bacteria can also be pathogens in skin and soft tissue infections. A summary of skin and soft tissue infections caused by coagulase-negative staphylococcus species is provided in this review. We conducted a search of the PubMed database using the following terms: abscess, auricularis, biofilm, capitis, cellulitis, coagulase, contaminant, cyst, draining, epidermidis, felon, folliculitis, furuncle, haemolyticus, hominis, indolent, infection, lugdunensis, mecA, microbiome, negative, osteomyelitis, paronychia, saprophyticus, skin, simulans, sinus, soft, staphylococcus, systemic, tissue, virulence, virulent, and vulvar...
June 7, 2018: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/29879096/invasive-methicillin-resistant-staphylococcus-aureus-infections-among-persons-who-inject-drugs-six-sites-2005-2016
#20
Kelly A Jackson, Michele K Bohm, John T Brooks, Alice Asher, Joelle Nadle, Wendy M Bamberg, Sue Petit, Susan M Ray, Lee H Harrison, Ruth Lynfield, Ghinwa Dumyati, William Schaffner, John M Townes, Isaac See
In the United States, age-adjusted opioid overdose death rates increased by >200% during 1999-2015, and heroin overdose death rates increased nearly 300% during 2011-2015 (1). During 2011-2013, the rate of heroin use within the past year among U.S. residents aged ≥12 years increased 62.5% overall and 114.3% among non-Hispanic whites, compared with 2002-2004 (2). Increases in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections related to increases in injection drug use have been recently highlighted (3,4); likewise, invasive bacterial infections, including endocarditis, osteomyelitis, and skin and soft tissue infections, have increased in areas where the opioid epidemic is expanding (5-7)...
June 8, 2018: MMWR. Morbidity and Mortality Weekly Report
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