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FDG-PET

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https://www.readbyqxmd.com/read/28528206/feasibility-of-atlas-based-active-bone-marrow-sparing-intensity-modulated-radiation-therapy-for-cervical-cancer
#1
Nan Li, Sonal S Noticewala, Casey W Williamson, Hanjie Shen, Igor Sirak, Rafal Tarnawski, Umesh Mahantshetty, Carl K Hoh, Kevin L Moore, Loren K Mell
BACKGROUND: To test the hypothesis that atlas-based active bone marrow (ABM)-sparing intensity modulated radiation therapy (IMRT) yields similar dosimetric results compared to custom ABM-sparing IMRT for cervical cancer patients. METHODS: We sampled 62 cervical cancer patients with pre-treatment FDG-PET/CT in training (n=32) or test (n=30) sets. ABM was defined as the subvolume of the pelvic bone marrow (PBM) with standardized uptake value (SUV) above the mean on the average FDG-PET image (ABMAtlas) vs...
May 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28527205/moderate-physical-activity-is-associated-with-cerebral-glucose-metabolism-in-adults-at-risk-for-alzheimer-s-disease
#2
Ryan J Dougherty, Stephanie A Schultz, Taylor K Kirby, Elizabeth A Boots, Jennifer M Oh, Dorothy Edwards, Catherine L Gallagher, Cynthia M Carlsson, Barbara B Bendlin, Sanjay Asthana, Mark A Sager, Bruce P Hermann, Bradley T Christian, Sterling C Johnson, Dane B Cook, Ozioma C Okonkwo
The objective of this study was to investigate the relationship between accelerometer-measured physical activity (PA) and glucose metabolism in asymptomatic late-middle-aged adults. Ninety-three cognitively healthy late-middle-aged adults from the Wisconsin Registry for Alzheimer's Prevention participated in this cross-sectional study. They underwent 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and wore an accelerometer (ActiGraph GT3X+) to measure free-living PA. Accelerometer data yielded measures of light (LPA), moderate (MPA), and vigorous (VPA) intensity PA...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28526417/imaging-of-a-pelvic-textiloma-using-18-f-fdg-pet-ct-in-a-patient-with-a-history-of-prostate-cancer-a-case-report-and-review-of-the-literature
#3
Romain Schollhammer, Henri De Clermont-Gallerande, Philippe Fernandez, Marie Meyer
No abstract text is available yet for this article.
April 26, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28526323/-18-f-fdg-pet-ct-helps-in-unmasking-the-great-mimicker-a-case-of-neurosarcoidosis-with-isolated-involvement-of-the-spinal-cord
#4
A Gholamrezanezhad, L Mehta
A 36 year-old male with no significant past medical history presented with lower extremity numbness, gait instability, and urinary and bowel retention of 4 weeks onset. Spine MRI revealed diffuse oedema of cervicothoracic spinal cord with several solid enhancing intramedullary lesions, suggestive of metastases. The (18)F-FDG PET/CT performed to identify the primary malignancy demonstrated mild hypermetabolic foci within the cervicothoracic cord, as well as a mildly hypermetabolic bilateral hilar lymphadenopathy and a mildly hypermetabolic pulmonary nodule, suggestive of sarcoidosis versus metastasis...
May 16, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28525463/fdg-pet-ct-as-a-new-method-for-diagnosis-and-whole-body-evaluation-of-lemierre-syndrome
#5
Jordy P Pijl, Andor W J M Glaudemans, Riemer H J A Slart, Thomas C Kwee
Lemierre syndrome is a rare disease that is defined by a pharyngeal infection, complicated by septicemia and internal jugular vein thrombosis followed by septic emboli. Because of its rarity, a delay in diagnosis is not uncommon. However, given the mortality rate of approximately 2%, prompt diagnosis and detection of septic emboli are essential to initiate prompt treatment, preventing organ damage and ongoing sepsis. We present 3 cases that demonstrate the value of FDG-PET/CT as a possible alternative or adjunct to conventional imaging methods for diagnosis and whole-body evaluation of Lemierre syndrome...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525461/18f-fdg-pet-ct-of-papillary-carcinoma-in-a-lateral-thyroglossal-duct-cyst
#6
Christos Sachpekidis, Matthias S Dettmer, Sabine Weidner, Roland Giger, Jan Wartenberg
A 69-year-old man presented with bulging of the right oropharyngeal wall, which revealed cytopathologically malignant cells. The man underwent MRI and F-FDG PET/CT, which demonstrated a cystic parapharyngeal lesion with an F-FDG-avid soft tissue component and right cervical lymph node. The patient was operated on and showed thyroid cancer in normal thyroid tissue, compatible with a papillary thyroid carcinoma in a lateral thyroglossal duct cyst and 2 ipsilateral lymph node metastases. Despite its rarity, papillary thyroid carcinoma in a thyroglossal duct cyst should be kept as one of the differential diagnoses in patients presenting with parapharyngeal cystic lesion...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525459/the-impact-of-a-bayesian-penalized-likelihood-reconstruction-algorithm-on-the-evaluation-of-indeterminate-pulmonary-nodules-by-dual-time-point-18f-fdg-pet-ct
#7
Tiago Sampaio Vieira, Diogo Borges Faria, Fernando Azevedo Silva, Francisco Pimentel, José Pereira de Oliveira
We present the case of a patient with history of colon cancer, referred for the evaluation of indeterminate pulmonary nodules by F-FDG PET/CT. A dual-time point protocol was performed, and images were reconstructed using VUE Point HD and a Bayesian-penalized likelihood reconstruction algorithm (Q.Clear). Visually, the quality of the images was considered better when Q.Clear was used with β value of 200, uptake in the smallest nodule (7 mm) was clearly visible only with Q.Clear reconstruction, and uptake in the smaller nodules was best defined in the delayed time point acquisition...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525457/stensen-duct-relapse-of-diffuse-large-b-cell-lymphoma-an-unusual-pattern-detected-with-18f-fdg-pet-ct
#8
Punit Sharma, Shilpa Bhartia
F-FDG PET/CT is now an established modality for staging and restaging high-grade lymphomas, including diffuse large B-cell lymphoma. We here present the case of a 51-year-old woman successfully treated for diffuse large B-cell lymphoma. Follow-up F-FDG PET/CT demonstrated an unusual site of relapse involving left Stensen (parotid) duct, which was confirmed with cytology. By identifying such unusual sites of lymphomatous involvement, F-FDG PET/CT can have significant bearing on patient management.
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525455/18f-fdg-pet-ct-of-malignant-angiomyolipoma-with-tumor-thrombus
#9
Andrew Griffin
Renal angiomyolipomas are the most common renal mesenchymal tumors. While classic angiomyolipomas are benign, there are a number of other subtypes. Epithelioid variants are potentially malignant and may be indistinguishable from renal cell carcinoma on imaging. We present a 52-year-old woman who underwent left nephrectomy for an aggressive-appearing malignant renal epithelioid angiomyolipoma. At 6 months postoperatively, restaging FDG PET/CT demonstrated a hypermetabolic left adrenal mass extending to the left adrenal vein, left renal vein, inferior vena cava, and right atrium (SUVmax = 12)...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525454/bilateral-tibial-osteofibrous-dysplasia-on-18f-fdg-pet-ct
#10
Hiroaki Nagano, Megumi Jinguji, Masanori Nakajo, Michiyo Higashi, Takashi Yoshiura
A 17-year-old girl had pain in the right front lower leg while road racing 2 months earlier. Radiography and CT showed osteolytic lesions in the medial part of the bilateral tibia. Bone scintigraphy showed focally increased radiotracer uptake in the bilateral tibia. The lesions showed hypermetabolism on FDG PET/CT. Osteofibrous dysplasia was suspected from the radiographic findings, but adamantinoma or metastases could not be excluded. Surgical biopsies were performed, and histopathologic studies confirmed the diagnosis of bilateral osteofibrous dysplasia...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525452/concomitant-lung-cancer-and-gastrointestinal-stromal-tumor-first-report-of-hypoxia-imaging-with-18f-faza-pet-ct
#11
Paola Mapelli, Elena Incerti, Federico Fallanca, Valentino Bettinardi, Antonia Compierchio, Valeria Masiello, Claudio Doglioni, Francesca Rossetti, Giampiero Negri, Luigi Gianolli, Maria Picchio
A 76-year-old man underwent F-FDG PET/CT to complete staging and characterize a suspicious lung mass. Images showed intense uptake in the lung lesion and faint uptake in correspondence of a gastric mass, which was subsequently biopsied revealing a gastrointestinal stromal tumor. A F-FAZA PET/CT was also performed because of patient's enrollment in a prospective clinical trial (trial registration no. EudraCT 2011-002647-98), showing heterogeneous uptake of F-FAZA in the pulmonary lesion and faint uptake in correspondence of the gastrointestinal stromal tumor...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525450/neuroblastoma-presenting-as-non-mibg-avid-widespread-soft-tissue-metastases-without-bone-involvement-revealed-by-fdg-pet-ct-imaging
#12
Nelleke Tolboom, Sabah E Servaes, Hongming Zhuang
Soft tissue metastases from neuroblastoma very rarely occur without concurrent osseous metastases. We report 1 case of non-MIBG-avid, high-risk neuroblastoma in a pediatric patient who had widespread soft tissue metastases without concurrent osseous lesion on FDG PET/CT imaging.
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525449/spontaneous-recovery-of-rosai-dorfman-disease-on-fdg-pet-ct
#13
Qianqian Xue, Weibing Miao
Rosai-Dorfman disease is a rare systemic proliferative disorder of histiocytes, which mainly manifests as lymphadenopathy but also often involves extranodal tissues. Rosai-Dorfman disease was often self-limited. We hereby report a case of Rosai-Dorfman disease involving both the lymph nodes and the lungs, which was spontaneously resolved on FDG PET/CT.
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28524708/significance-of-baseline-fdg-pet-ct-scan-as-a-method-of-staging-regional-lymph-nodes-in-patients-with-operable-distal-oesophageal-or-gastroesophageal-junction-adenocarcinoma
#14
George Papaxoinis, Jamie M J Weaver, Leila Khoja, Ana Patrao, Sofia Stamatopoulou, Alia Alchawaf, Vikki Owen-Holt, Theodora Germetaki, Zoe Kordatou, Wasat Mansoor
BACKGROUND: The new American Joint Committee on Cancer eighth edition (AJCC8) staging is the first to describe separate clinical and pathology staging systems, but still has low performance to predict prognosis in patients with oesophageal/gastroesophageal junction (O/GOJ) adenocarcinoma, who are candidates for surgery. Recent studies have demonstrated that O/GOJ cancer patients with 18F-fluorodeoxyglucose (FDG) avid regional lymph nodes (RLNs) may have poor prognosis. The aim of our study was to examine whether the baseline assessment of the FDG uptake of RLN improves the prognostic accuracy of the new AJCC8 staging...
May 19, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28523353/evaluation-of-renal-cell-carcinoma-histological-subtype-and-fuhrman-grade-using-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#15
Reiko Nakajima, Sayumi Nozaki, Tsunenori Kondo, Yoji Nagashima, Koichiro Abe, Shuji Sakai
OBJECTIVES: We evaluated (18)F-fluorodeoxyglucose (FDG) uptake by renal cell carcinomas (RCCs) to determine whether different histological subtypes and Fuhrman grades can be distinguished. METHODS: We retrospectively reviewed the records and maximum standardised uptake value (SUVmax) of 147 patients with 154 RCCs who underwent FDG-positron emission tomography (PET)/computed tomography (CT) prior to tumour resection. RESULTS: The SUVmax was significantly lower in chromophobe RCC (chRCC) tumours than in clear cell RCC (ccRCC; p = 0...
May 18, 2017: European Radiology
https://www.readbyqxmd.com/read/28523180/primary-atypical-carcinoid-tumor-of-the-mediastinum-a-very-rare-finding
#16
Luigi Ventura, Letizia Gnetti, Enrico Maria Silini, Guido Rindi, Paolo Carbognani, Michele Rusca, Luca Ampollini
Primary neuroendocrine tumors (NETs) of the mediastinum are very rare. Prognosis is usually poor despite treatment options. We present the case of a primary atypical carcinoid tumor of the mediastinum successfully treated by multimodal approach. A 50-year-old man presented for asthenia, dyspnea, and substernal sense of weight for two weeks. A chest-CT scan revealed a tumor mass of 107×55×95 mm(3) localized in the anterosuperior mediastinum compressing both brachiocephalic veins, the superior vena cava, the pericardium, and lungs...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28523157/impact-of-maximum-standardized-uptake-value-of-non-small-cell-lung-cancer-on-detecting-lymph-node-involvement-in-potential-stereotactic-body-radiotherapy-candidates
#17
Shanyuan Zhang, Shaolei Li, Yuquan Pei, Miao Huang, Fangliang Lu, Qingfeng Zheng, Nan Li, Yue Yang
BACKGROUND: The retrospective study investigated the association between the maximum standardized uptake value (SUVmax) of primary tumor and lymph node involvement in potential stereotactic body radiotherapy (SBRT) candidates. METHODS: A total of 185 patients with clinical stage I NSCLC were enrolled in the current study. All patients underwent lobectomy with systematic lymph node dissection following preoperative FDG-PET/CT scanning. The association between clinicopathological variables and lymph node involvement was analyzed by univariate and multivariate analysis...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522951/diagnostic-and-prognostic-value-of-preoperative-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-colorectal-cancer-comparison-with-conventional-computed-tomography
#18
Joo Young Lee, Soon Man Yoon, Jeong Tae Kim, Ki Bae Kim, Mi Jin Kim, Jae Geun Park, Taek-Gu Lee, Sang-Jeon Lee, Sung Soo Koong, Joung-Ho Han, Hee Bok Chae, Seon Mee Park, Sei Jin Youn
BACKGROUND/AIMS: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has been used for preoperative staging of colorectal cancer (CRC). However, the diagnostic accuracy of FDG-PET/CT for detection of lymph node or distant metastasis and its prognostic role have not been well established. We therefore evaluated the diagnostic and prognostic value of FDG-PET/CT in comparison with conventional CT for CRC. METHODS: We investigated 220 patients who underwent preoperative FDG-PET/CT and CT, followed by curative surgery for CRC...
April 2017: Intestinal Research
https://www.readbyqxmd.com/read/28522744/fdg-pet-response-after-induction-chemotherapy-can-predict-who-will-benefit-from-subsequent-esophagectomy-after-chemoradiotherapy-for-esophageal-adenocarcinoma
#19
Mian Xi, Zhongxing Liao, Wayne L Hofstetter, Ritsuko Komaki, Linus Ho, Steven H Lin
This study aimed to determine whether (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) response after induction chemotherapy before concurrent chemoradiotherapy can identify patients with esophageal adenocarcinoma who may benefit from subsequent esophagectomy. Methods: We identified and analyzed 220 patients with esophageal adenocarcinoma who had received induction chemotherapy before chemoradiotherapy, with or without surgery, with curative intent; all underwent FDG-PET scanning before and after induction chemotherapy...
May 18, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28522739/imaging-macrophage-accumulation-in-a-murine-model-of-chronic-pancreatitis-with-125-i-iododpa-spect-ct
#20
Catherine A Foss, Liansheng Liu, Ronnie C Mease, Haofan Wang, Pankaj Pasricha, Martin G Pomper
Background and Aims: Pancreatitis remains a diagnostic challenge in patients with mild to moderate disease, with current imaging modalities inadequate. Given the prominent macrophage infiltrate in chronic pancreatitis, we hypothesized that (125)I-iodo-DPA-713 (iodoDPA), a small-molecule radiotracer that specifically targets macrophages, could be used with single photon emission computed tomography-computed tomography (SPECT-CT) to image pancreatic inflammation in a relevant experimental model. Methods: Chronic pancreatitis was induced in C57BL/6 mice with cerulein and were contrasted with vehicle-injected controls...
May 18, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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