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"Brain plasticity"

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https://www.readbyqxmd.com/read/29781450/music-brain-plasticity-and-the-resilience-the-pillars-of-new-receptive-therapy
#1
Helena Dukić
This paper describes a new type of receptive music therapy which aims to build the patients' psychological resilience by increasing the levels of dopamine, serotonin and oxytocin in order to increase standard psychopharmacological treatment efficiency. Previous research concerning the musically induced production of the two neurotransmitters and a hormone is discussed and reviewed. Based upon the existent studies concerning the influence of music on dopamine, serotonin and oxytocin induction, a new design of specific music features for this purpose is proposed and elaborated upon...
April 2018: Psychiatria Danubina
https://www.readbyqxmd.com/read/29779103/dopamine-synthesis-as-a-mechanism-of-brain-plasticity-in-nigrostriatal-system-pathology
#2
A A Kolacheva, M V Ugrumov
Using an experimental Parkinson's disease model (symptoms develop in mice after the injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), we studied the characteristics of the synthesis of dopamine as a possible compensatory mechanism aimed at maintaining the dopamine level in the dopaminergic neurons that survived in this pathology. We found no correlation between the content and activity of tyrosine hydroxylase in the nigrostriatal system. The enzyme activity and the dopamine content showed unidirectional changes in the substantia nigra, but not in the striatum, which is apparently due to triggering other compensatory mechanisms...
March 2018: Doklady. Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29775542/exercise-and-circulating-bdnf-mechanisms-of-release-and-implications-for-the-design-of-exercise-interventions
#3
Jeremy James Walsh, Michael E Tschakovsky
Engagement in regular bouts of exercise confers numerous positive effects on brain health across the lifespan. Acute bouts of exercise transiently improve cognitive function, while long-term exercise training stimulates brain plasticity, improves brain function, and helps to stave off neurological disease. The action of brain-derived neurotrophic factor (BDNF) is a candidate mechanism underlying these exercise-induced benefits and is the subject of considerable attention in the exercise-brain health literature...
May 18, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29765864/non-canonical-post-transcriptional-rna-regulation-of-neural-stem-cell-potential
#4
REVIEW
Chiara Rolando, Verdon Taylor
Adult brain structures and complexity emerge from a single layer of neuroepithelial cells that early during the development give rise to neural stem cells (NSCs). NSCs persist in restricted regions of the postnatal brain where they support neurogenesis throughout life thus allowing brain plasticity and adaptation. NSC regulation involves a precise coordination of intrinsic and extrinsic mechanisms that finely modulate the neurogenic process. Here we will discuss new mechanisms of post-transcriptional gene regulation that act in the embryonic and adult brain to regulate NSC maintenance and differentiation...
November 9, 2017: Brain Plasticity
https://www.readbyqxmd.com/read/29765857/dna-methylation-and-adult-neurogenesis
#5
REVIEW
Emily M Jobe, Xinyu Zhao
The role of DNA methylation in brain development is an intense area of research because the brain has particularly high levels of CpG and mutations in many of the proteins involved in the establishment, maintenance, interpretation, and removal of DNA methylation impact brain development and/or function. These include DNA methyltransferase (DNMT), Ten-Eleven Translocation (TET), and Methyl-CpG binding proteins (MBPs). Recent advances in sequencing breadth and depth as well the detection of different forms of methylation have greatly expanded our understanding of the diversity of DNA methylation in the brain...
November 9, 2017: Brain Plasticity
https://www.readbyqxmd.com/read/29755514/motor-improvement-of-skilled-forelimb-use-induced-by-treatment-with-growth-hormone-and-rehabilitation-is-dependent-on-the-onset-of-the-treatment-after-cortical-ablation
#6
Margarita Heredia, Jesús Palomero, Antonio de la Fuente, José María Criado, Javier Yajeya, Jesús Devesa, Pablo Devesa, José Luis Vicente-Villardón, Adelaida S Riolobos
We previously demonstrated that the administration of GH immediately after severe motor cortex injury, in rats, followed by rehabilitation, improved the functionality of the affected limb and reexpressed nestin in the contralateral motor cortex. Here, we analyze whether these GH effects depend on a time window after the injury and on the reexpression of nestin and actin. Injured animals were treated with GH (0.15 mg/kg/day) or vehicle, at days 7, 14, and 35 after cortical ablation. Rehabilitation was applied at short and long term (LTR) after the lesion and then sacrificed...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29755380/effects-of-physical-exercise-on-cognitive-functioning-and-wellbeing-biological-and-psychological-benefits
#7
REVIEW
Laura Mandolesi, Arianna Polverino, Simone Montuori, Francesca Foti, Giampaolo Ferraioli, Pierpaolo Sorrentino, Giuseppe Sorrentino
Much evidence shows that physical exercise (PE) is a strong gene modulator that induces structural and functional changes in the brain, determining enormous benefit on both cognitive functioning and wellbeing. PE is also a protective factor for neurodegeneration. However, it is unclear if such protection is granted through modifications to the biological mechanisms underlying neurodegeneration or through better compensation against attacks. This concise review addresses the biological and psychological positive effects of PE describing the results obtained on brain plasticity and epigenetic mechanisms in animal and human studies, in order to clarify how to maximize the positive effects of PE while avoiding negative consequences, as in the case of exercise addiction...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29752710/inflammation-in-psychiatric-disorders-what-comes-first
#8
REVIEW
Moisés E Bauer, Antonio L Teixeira
Neuropsychiatric disorders (i.e., mood disorders and schizophrenia) and inflammation are closely intertwined, and possibly powering each other in a bidirectional loop. Depression facilitates inflammatory reactions and inflammation promotes depression and other neuropsychiatric disorders. Patients with neuropsychiatric disorders exhibit all cardinal features of inflammation, including increased circulating levels of inflammatory inducers, activated sensors, and inflammatory mediators targeting all tissues. Inflammation may contribute to the pathophysiology and clinical progression of these disorders...
May 11, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29723600/cognitive-training-with-action-related-verbs-induces-neural-plasticity-in-the-action-representation-system-as-assessed-by-gray-matter-brain-morphometry
#9
Marta Ghio, Matteo Locatelli, Andrea Tettamanti, Daniela Perani, Roberto Gatti, Marco Tettamanti
Embodied cognition theories of semantic memory still face the need for multiple sources of converging evidence in support of the involvement of sensory-motor systems in action-related knowledge. Previous studies showed that training manual actions improves semantic processing of verbs referring to the trained actions. The present work aimed to provide complementary evidence by measuring the brain plasticity effects of a cognitive training requiring sustained lexical-semantic processing of action-related verbs...
April 30, 2018: Neuropsychologia
https://www.readbyqxmd.com/read/29709023/relationship-between-brain-plasticity-learning-and-foraging-performance-in-honey-bees
#10
Amélie Cabirol, Alex J Cope, Andrew B Barron, Jean-Marc Devaud
Brain structure and learning capacities both vary with experience, but the mechanistic link between them is unclear. Here, we investigated whether experience-dependent variability in learning performance can be explained by neuroplasticity in foraging honey bees. The mushroom bodies (MBs) are a brain center necessary for ambiguous olfactory learning tasks such as reversal learning. Using radio frequency identification technology, we assessed the effects of natural variation in foraging activity, and the age when first foraging, on both performance in reversal learning and on synaptic connectivity in the MBs...
2018: PloS One
https://www.readbyqxmd.com/read/29706867/rna-sequencing-reveals-unique-transcriptional-signatures-of-running-and-running-independent-environmental-enrichment-in-the-adult-mouse-dentate-gyrus
#11
Catherine-Alexandra Grégoire, Stephanie Tobin, Brianna L Goldenstein, Éric Samarut, Andréanne Leclerc, Anne Aumont, Pierre Drapeau, Stephanie Fulton, Karl J L Fernandes
Environmental enrichment (EE) is a powerful stimulus of brain plasticity and is among the most accessible treatment options for brain disease. In rodents, EE is modeled using multi-factorial environments that include running, social interactions, and/or complex surroundings. Here, we show that running and running-independent EE differentially affect the hippocampal dentate gyrus (DG), a brain region critical for learning and memory. Outbred male CD1 mice housed individually with a voluntary running disk showed improved spatial memory in the radial arm maze compared to individually- or socially-housed mice with a locked disk...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29700896/task-related-fmri-in-hemiplegic-cerebral-palsy-a-systematic-review
#12
REVIEW
Katerina Gaberova, Iliyana Pacheva, Ivan Ivanov
RATIONALE: Functional magnetic resonance imaging (fMRI) is used widely to study reorganization after early brain injuries. Unilateral cerebral palsy (UCP) is an appealing model for studying brain plasticity by fMRI. AIM: To summarize the results of task-related fMRI studies in UCP in order to get better understanding of the mechanism of neuroplasticity of the developing brain and its reorganization potential and better translation of this knowledge to clinical practice...
April 27, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29696239/effects-and-mechanism-of-the-hect-study-hybrid-exercise-cognitive-trainings-in-mild-ischemic-stroke-with-cognitive-decline-fmri-for-brain-plasticity-biomarker-and-behavioral-analysis
#13
Ting-Ting Yeh, Ku-Chou Chang, Ching-Yi Wu, Ya-Yun Lee, Po-Yu Chen, Jen-Wen Hung
Purpose: Cognitive decline after stroke is highly associated with functional disability. Empirical evidence shows that exercise combined cognitive training may induce neuroplastic changes that modulate cognitive function. However, it is unclear whether hybridized exercise-cognitive training can facilitate cortical activity and physiological outcome measures and further influence on the cognitive function after stroke. This study will investigate the effects of two hybridized exercise-cognitive trainings on brain plasticity, physiological biomarkers and behavioral outcomes in stroke survivors with cognitive decline...
March 2018: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29695280/shaping-neuroplasticity-by-using-powered-exoskeletons-in-patients-with-stroke-a-randomized-clinical-trial
#14
Rocco Salvatore Calabrò, Antonino Naro, Margherita Russo, Placido Bramanti, Luigi Carioti, Tina Balletta, Antonio Buda, Alfredo Manuli, Serena Filoni, Alessia Bramanti
BACKGROUND: The use of neurorobotic devices may improve gait recovery by entraining specific brain plasticity mechanisms, which may be a key issue for successful rehabilitation using such approach. We assessed whether the wearable exoskeleton, Ekso™, could get higher gait performance than conventional overground gait training (OGT) in patients with hemiparesis due to stroke in a chronic phase, and foster the recovery of specific brain plasticity mechanisms. METHODS: We enrolled forty patients in a prospective, pre-post, randomized clinical study...
April 25, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29694337/experimental-cerebral-hemispherectomy-in-rodent-models-a-systematic-review-of-current-literature
#15
Cezar Octavian Morosanu, Razvan Lucian Jurca, Larisa Simonca, Roxana Flavia Ilies, Remus Moldovan, Ioan Stefan Florian, Gabriela Adriana Filip
Cerebral hemispherectomy is a neurosurgical procedure that involves surgically removing one hemisphere of the brain, used as a therapeutic option in severe cases of intractable epilepsy. Several animal models have contributed to our understanding of the underlying neuromechanisms. The review was based on a PubMed search using the terms "hemispherectomy" and "mouse" or "rat" or "rodent", with no limitation of year of study or language. We identified a series of elements that were collected and analyzed that add up to our contemporary knowledge of this procedure...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29672597/naturalistic-music-and-dance-cortical-phase-synchrony-in-musicians-and-dancers
#16
Hanna Poikonen, Petri Toiviainen, Mari Tervaniemi
Expertise in music has been investigated for decades and the results have been applied not only in composition, performance and music education, but also in understanding brain plasticity in a larger context. Several studies have revealed a strong connection between auditory and motor processes and listening to and performing music, and music imagination. Recently, as a logical next step in music and movement, the cognitive and affective neurosciences have been directed towards expertise in dance. To understand the versatile and overlapping processes during artistic stimuli, such as music and dance, it is necessary to study them with continuous naturalistic stimuli...
2018: PloS One
https://www.readbyqxmd.com/read/29627940/effects-of-motor-rehabilitation-on-mobility-and-brain-plasticity-in-multiple-sclerosis-a-structural-and-functional-mri-study
#17
Eleonora Tavazzi, Niels Bergsland, Davide Cattaneo, Elisa Gervasoni, Maria Marcella Laganà, Ottavia Dipasquale, Cristina Grosso, Francesca Lea Saibene, Francesca Baglio, Marco Rovaris
BACKGROUND: Rehabilitation seems to promote brain plasticity, but objective measures of efficacy are lacking and there is a limited understanding of the mechanisms underlying functional recovery. OBJECTIVE: To study functional and structural brain changes induced by gait rehabilitation. METHODS: We enrolled MS inpatients (EDSS 4.5-6.5) undergoing a 4-week neurorehabilitation. Several clinical measures were obtained, including: 2-min walk test (2MWT), dynamic gait index (DGI), Berg balance scale (BBS)...
April 7, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29615367/boosting-the-ltp-like-plasticity-effect-of-intermittent-theta-burst-stimulation-using-gamma-transcranial-alternating-current-stimulation
#18
Andrea Guerra, Antonio Suppa, Matteo Bologna, Valentina D'Onofrio, Edoardo Bianchini, Peter Brown, Vincenzo Di Lazzaro, Alfredo Berardelli
BACKGROUND: Transcranial Alternating Current Stimulation (tACS) consists in delivering electric current to the brain using an oscillatory pattern that may entrain the rhythmic activity of cortical neurons. When delivered at gamma frequency, tACS modulates motor performance and GABA-A-ergic interneuron activity. OBJECTIVE: Since interneuronal discharges play a crucial role in brain plasticity phenomena, here we co-stimulated the primary motor cortex (M1) in healthy subjects by means of tACS during intermittent theta-burst stimulation (iTBS), a transcranial magnetic stimulation paradigm known to induce long-term potentiation (LTP)-like plasticity...
March 24, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29593782/bilateral-transcranial-direct-current-stimulation-reshapes-resting-state-brain-networks-a-magnetoencephalography-assessment
#19
Giovanni Pellegrino, Matteo Maran, Cristina Turco, Luca Weis, Giovanni Di Pino, Francesco Piccione, Giorgio Arcara
Transcranial direct current stimulation (tDCS) can noninvasively induce brain plasticity, and it is potentially useful to treat patients affected by neurological conditions. However, little is known about tDCS effects on resting-state brain networks, which are largely involved in brain physiological functions and in diseases. In this randomized, sham-controlled, double-blind study on healthy subjects, we have assessed the effect of bilateral tDCS applied over the sensorimotor cortices on brain and network activity using a whole-head magnetoencephalography system...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29593485/-till-death-do-us-part-a-potential-irreversible-link-between-aberrant-cell-cycle-control-and-neurodegeneration-in-the-adult-olfactory-bulb
#20
REVIEW
Saad Omais, Carine Jaafar, Noël Ghanem
Adult neurogenesis (AN) is an ongoing developmental process that generates newborn neurons in the olfactory bulb (OB) and the hippocampus (Hi) throughout life and significantly contributes to brain plasticity. Adult neural stem and progenitor cells (aNSPCs) are relatively limited in number and fate and are spatially restricted to the subventricular zone (SVZ) and the subgranular zone (SGZ). During AN, the distinct roles played by cell cycle proteins extend beyond cell cycle control and constitute key regulatory mechanisms involved in neuronal maturation and survival...
2018: Frontiers in Neuroscience
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