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https://www.readbyqxmd.com/read/29148317/brainstem-glioma-prediction-of-histopathologic-grade-based-on-conventional-mr-imaging
#1
Yashar Moharamzad, Morteza Sanei Taheri, Farhad Niaghi, Elham Shobeiri
Objective The objective of this article is to investigate the association between specific MR imaging findings and histopathologic grading (low-grade vs. high-grade) of brainstem gliomas (BSGs). Methods Sixty-two males and 34 females (mean (standard deviation, SD) age of 24.61 (17.20) years, range = 3 to 70 years) with histologically diagnosed BSG underwent conventional 1.5 T MR imaging, which included T1-weighted (T1W), T2W, and post-contrast T1W sequences. There were 39 children (mean age of 9.38 years) and 57 adults (mean age of 35 years)...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29122851/guidelines-on-the-management-of-abnormal-liver-blood-tests
#2
Philip N Newsome, Rob Cramb, Suzanne M Davison, John F Dillon, Mark Foulerton, Edmund M Godfrey, Richard Hall, Ulrike Harrower, Mark Hudson, Andrew Langford, Anne Mackie, Robert Mitchell-Thain, Karen Sennett, Nicholas C Sheron, Julia Verne, Martine Walmsley, Andrew Yeoman
These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines, which this document supersedes, were written in 2000 and have undergone extensive revision by members of the Guidelines Development Group (GDG). The GDG comprises representatives from patient/carer groups (British Liver Trust, Liver4life, PBC Foundation and PSC Support), elected members of the BSG liver section (including representatives from Scotland and Wales), British Association for the Study of the Liver (BASL), Specialist Advisory Committee in Clinical Biochemistry/Royal College of Pathology and Association for Clinical Biochemistry, British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN), Public Health England (implementation and screening), Royal College of General Practice, British Society of Gastrointestinal and Abdominal Radiologists (BSGAR) and Society of Acute Medicine...
November 9, 2017: Gut
https://www.readbyqxmd.com/read/29121374/boomerang-shaped-vs-shield-shaped-chondroperichondrial-cartilage-grafts-for-type-1-tympanoplasty-in-children-a-study-of-121-patients
#3
Can Özbay, Fatih Kemal Soy, Erkan Kulduk, Riza Dundar, Ahmet Yükkaldiran, Osman Kadir Güler, Ertan Koç
Many techniques and graft materials have been used for the reconstruction of the tympanic membrane. We conducted a retrospective study to compare anatomic and functional outcomes of type 1 tympanoplasty that we performed with boomerang-shaped chondroperichondrial cartilage grafts (BSGs) and shield-shaped chondroperichondrial cartilage grafts (SSGs) in pediatric patients. Our study population was made up 121 patients-61 boys and 60 girls, aged 7 to 16 years (mean: 12.4)-who had undergone a type 1 tympanoplasty...
October 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29118919/integrative-analysis-of-bsg-expression-in-npc-through-immunohistochemistry-and-public-high-throughput-gene-expression-data
#4
Li Gao, Jin-Cai Zhong, Wen-Ting Huang, Yi-Wu Dang, Min Kang, Gang Chen
BACKGROUND: Though basigin (BSG) was reported to be overexpressed in nasopharyngeal carcinoma (NPC) and correlate with the development of NPC, the molecular basis of BSG in NPC remained elusive. The aim of the research was to investigate BSG expression in NPC and the potential molecular mechanism underlying it. MATERIALS AND METHODS: BSG expression in NPC tissues was detected with immunohistochemistry. Chi-square test, Kruskal-Wallis test and Spearman correlation test were performed to examine the relationship between BSG expression and the clinico-pathological features as well as EGFR and P-53 expression in NPC...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29091853/hydrolytic-pre-treatment-methods-for-enhanced-biobutanol-production-from-agro-industrial-wastes
#5
Sampa Maiti, Gorka Gallastegui, Gayatri Suresh, Saurabh Jyoti Sarma, Satinder Kaur Brar, Patrick Drogui, Yann LeBihan, Gerardo Buelna, Mausam Verma, Carlos Ricardo Soccol
Brewery industry liquid waste (BLW), brewery spent grain (BSG), apple pomace solid wastes (APS), apple pomace ultrafiltration sludge (APUS) and starch industry wastewater (SIW) have been considered as substrates to produce biobutanol. Efficiency of hydrolysis techniques tested to produce fermentable sugars depended on nature of agro-industrial wastes and process conditions. Acid-catalysed hydrolysis of BLW and BSG gave a total reducing sugar yield of 0.433 g/g and 0.468 g/g respectively. Reducing sugar yield from microwave assisted hydrothermal method was 0...
October 5, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29090311/randomized-controlled-trial-of-a-novel-device-for-tinnitus-sound-therapy-during-sleep
#6
Sarah M Theodoroff, Garnett P McMillan, Tara L Zaugg, Megan Cheslock, Chan Roberts, James A Henry
Purpose: The aim of this study was to determine if a customized stimulus from the Otoharmonics Levo System reduces tinnitus perceptions and reactions for people with bothersome tinnitus. Method: Sixty participants were randomized to 1 of 3 groups that used sound therapy devices during sleep that differed in their acoustic stimulus: (a) tinnitus-matched (TM), (b) noise stimulus (NS), and (c) bedside sound generator (BSG). Outcome measures were the Tinnitus Functional Index (TFI), numeric rating scale of tinnitus loudness, and tinnitus loudness match...
October 31, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29078358/crispr-cas9-knockouts-reveal-genetic-interaction-between-strain-transcendent-erythrocyte-determinants-of-plasmodium-falciparum-invasion
#7
Usheer Kanjee, Christof Grüring, Mudit Chaand, Kai-Min Lin, Elizabeth Egan, Jale Manzo, Patrick L Jones, Tiffany Yu, Robert Barker, Michael P Weekes, Manoj T Duraisingh
During malaria blood-stage infections, Plasmodium parasites interact with the RBC surface to enable invasion followed by intracellular proliferation. Critical factors involved in invasion have been identified using biochemical and genetic approaches including specific knockdowns of genes of interest from primary CD34(+) hematopoietic stem cells (cRBCs). Here we report the development of a robust in vitro culture system to produce RBCs that allow the generation of gene knockouts via CRISPR/Cas9 using the immortal JK-1 erythroleukemia line...
October 31, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29063354/effects-of-substituting-sow-and-weaner-meal-with-brewers-spent-grains-on-the-performance-of-growing-pigs-in-rwanda
#8
Mary Anne Mukasafari, Mary K Ambula, Callixte Karege, Anthony M King'ori
Nutrient composition of brewers' spent grains (BSG) from two industries and sow and weaner meal (SWM) were different (p < 0.05). In completely randomised design (CRD), thirty (30) Landrace x Pietrain crosses 35 to 40 ± 5 kg were randomly allocated to 10 pens each with 3 pigs based on the initial weight. Five diets were assigned to pig, where BSG replaced SWM at 0% (T1), 25% (T2), 50% (T3), 75% (T4) and 100% (T5) on DM basis. Daily feed intake and weekly live weight, feed conversion ratio (FCR) and the net profit were recorded for 42 days...
October 23, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29054964/gene-expression-profiling-of-the-notch-ahr-il22-axis-at-homeostasis-and-in-response-to-tissue-injury
#9
Marc Weidenbusch, Severin Rodler, Shangqing Song, Simone Romoli, Julian A Marschner, Franziska Kraft, Alexander Holderied, Santosh Kumar, Shrikant R Mulay, Mohsen Honarpisheh, Satish Kumar Devarapu, Maciej Lech, Hans-Joachim Anders
Notch and Interleukin-22 signaling are known to regulate tissue homeostasis and response to injury in humans and mice, and the induction of endogenous arylhydrocarbon receptor ligands through Notch links the two pathways in a hierarchical fashion. However, in adults the species-, organ- and injury-specific gene expression of the Notch-AhR-IL22 axis components is unknown. We therefore performed gene expression profiling of DLL1, DLL3, DLL4, DLK1, DLK2, JAG1, JAG2, Notch1, Notch2, Notch3, Notch4, ADAM17/TACE, PSEN1, BSG/CD147, RBP-J, HES1, HES5, HEY1, HEYL, AHR, ARNT, ARNT2, CYP1A1, CYP24A1, IL22, IL22RA1, IL22RA2, IL10RB, and STAT3 under homeostatic conditions in 10 mature murine and human organs...
October 20, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28993547/development-of-novel-therapies-for-cardiovascular-diseases-by-clinical-application-of-basic-research
#10
Kimio Satoh
Cyclophilin A (CyPA) is secreted from vascular smooth muscle cells, inflammatory cells, activated platelets, and cardiac fibroblasts in response to oxidative stress. Excessive and continuous activation of the RhoA/Rho-kinase system promotes the secretion of CyPA, resulting in the development of multiple cardiovascular diseases. Basigin (Bsg), a transmembrane glycoprotein that activates matrix metalloproteinases, is an extracellular receptor for CyPA that promotes cell proliferation and inflammation. Thus, the CyPA/Bsg system is potentially a novel therapeutic target for cardiovascular diseases...
October 6, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28981932/-the-role-of-mir-492-in-the-regulation-of-ok-blood-group-antigen-expression-on-red-blood-cells
#11
Luyi Ye, Chen Wang, Qixiu Yang, Ziyan Zhu
OBJECTIVE: To investigate whether miR-492 is involved in the post-transcriptional regulation of OK blood group antigen expression on red blood cells. METHODS: Two 3'-UTR fragments of the BSG gene were synthesized with a chemical method, which respectively encompassed the BSG rs8259 TT or BSG rs8259 AA sites. The fragments were added with Xho I and Not I restriction enzyme cutting sites at both ends and cloned into a pUC57 vector, which in turn was constructed into a psiCHECK-2 vector and verified by sequencing...
October 10, 2017: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/28918347/anaerobic-digestion-of-brewery-spent-grains-trace-elements-addition-requirement
#12
Claire Bougrier, Delphine Dognin, Cécile Laroche, Valérie Gonzalez, Dalel Benali-Raclot, Jesús Andrés Cacho Rivero
The current study evaluates and compares the stability of anaerobic digestion of Brewery Spent Grains (BSG) with and without addition of nutrients. Based on the composition of the BSG two levels of nutrients addition were defined. Control reactor, without addition of nutrients, showed signs of instability after 3months of operation and collapsed. On the contrary, supplemented reactors led to a COD removal rate of 60% and a methane production of 280NLCH4.kg(-1) VSadded. According to these results, it was possible to define an additive solution adapted to BSG degradation...
September 2, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28892257/candidate-gene-molecular-markers-as-tools-for-analyzing-genetic-susceptibility-to-morbillivirus-infection-in-stranded-cetaceans
#13
K Stejskalova, Z Bayerova, J Futas, K Hrazdilova, M Klumplerova, J Oppelt, P Splichalova, G Di Guardo, S Mazzariol, C E Di Francesco, G Di Francesco, G Terracciano, R-M Paiu, T D Ursache, D Modry, P Horin
Morbilliviruses, such as Cetacean morbillivirus (CeMV) or Phocine distemper virus (PDV), represent a growing threat for marine mammals on both hemispheres. Because free-ranging animal populations strongly rely on natural resistance mechanisms, innate immunity-related genes and virus cell entry receptor genes may represent key factors involved in susceptibility to CeMV in Cetaceans. Using the next generation sequencing technology, we have sequenced 11 candidate genes in two model species, Stenella coeruleoalba and Phocoena phocoena...
September 11, 2017: HLA
https://www.readbyqxmd.com/read/28873583/analysis-of-polyphenols-in-brewer-s-spent-grain-and-its-comparison-with-corn-silage-and-cereal-brans-commonly-used-for-animal-nutrition
#14
Flávia Santi Stefanello, Clarissa Obem Dos Santos, Vivian Caetano Bochi, Ana Paula Burin Fruet, Marcela Bromenberg Soquetta, Andréa Cristina Dörr, José Laerte Nörnberg
Brewer's spent grain (BSG) could be tested as an alternative source of polyphenols in animal nutrition. Proper extraction and analytical methods are critical for quantification. Thus, extraction for BSG, corn silage, and brans of rice, corn, and wheat were studied for the highest yield of polyphenols. A method for 18 phenolic monomers by HPLC-DAD was developed, validated, and applied to samples. An aqueous solution of NaOH (0.75% w/v) using integral samples for extraction resulted in the highest values for colorimetric measurements in all analyzed sources...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28839878/provision-of-out-of-hours-services-for-acute-upper-gastrointestinal-bleeding-in-england-results-of-the-2014-2015-bsg-nhs-england-national-survey
#15
Bahman Nedjat-Shokouhi, Michael Glynn, Erika R E Denton, Simon M Greenfield
BACKGROUND: There has been a drive to raise the standard of management of acute upper gastrointestinal bleeding (AUGIB) in the UK, including three previous audits, sponsored by the British Society of Gastroenterology (BSG). OBJECTIVE: To review the results of the latest BSG/National Health Service (NHS) England national survey of endoscopy services in England between 2014 and 2015. METHOD: All NHS hospitals accepting acute admissions in England (168) were invited to respond to the survey...
January 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/28833108/composition-and-nutrient-value-proposition-of-brewers-spent-grain
#16
REVIEW
Sana Ikram, LianYan Huang, Huijuan Zhang, Jing Wang, Meng Yin
Brewer's spent grain (BSG), a major brewing industry byproduct, is generated in large quantities annually. This review summarizes research into the composition and preservation of BSG, different extraction techniques for BSG proteins and phenolic acids, and the bioactivities of these phenolic components. Moreover, this article also highlights BSG integration into foodstuff for human consumption and animal feed supplements. BSG is considered a rich source of fiber, protein, and phenolic compounds. The phenolic acids present in BSG are hydroxycinnamic acids (ferulic, p-coumaric, and caffeic acids), which have many biofunctions, such as antioxidant, anticarcinogenic, antiatherogenic, and antiinflammatory activities...
October 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28821598/quality-standards-in-upper-gastrointestinal-endoscopy-a-position-statement-of-the-british-society-of-gastroenterology-bsg-and-association-of-upper-gastrointestinal-surgeons-of-great-britain-and-ireland-augis
#17
Sabina Beg, Krish Ragunath, Andrew Wyman, Matthew Banks, Nigel Trudgill, D Mark Pritchard, Stuart Riley, John Anderson, Helen Griffiths, Pradeep Bhandari, Phillip Kaye, Andrew Veitch
This document represents the first position statement produced by the British Society of Gastroenterology and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland, setting out the minimum expected standards in diagnostic upper gastrointestinal endoscopy. The need for this statement has arisen from the recognition that while technical competence can be rapidly acquired, in practice the performance of a high-quality examination is variable, with an unacceptably high rate of failure to diagnose cancer at endoscopy...
November 2017: Gut
https://www.readbyqxmd.com/read/28771745/biostimulants-from-food-processing-by-products-agronomic-quality-and-metabolic-impacts-on-organic-tomato-solanum-lycopersicum-l
#18
Lara Abou Chehade, Ziad Al Chami, Sandra Angelica De Pascali, Ivana Cavoski, Francesco Paolo Fanizzi
BACKGROUND: Biostimulants have recently gained increased attention due to their multiple benefits for sustainable agriculture. In this study, three food processing by-products - fennel processing residues (FPR), lemon processing residues (LPR) and brewer's spent grain (BSG) - were investigated as potential sources of biostimulants. Their aqueous extracts as individual and associated applications were assessed for their effects on agronomic, quality and metabolic performance of organic tomato in comparison to extract of humic substances (HS) and untreated control (CTRL)...
August 3, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28666637/bsg-annual-meeting-2017
#19
Rob Brierley
No abstract text is available yet for this article.
June 27, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28648256/a-comparative-analysis-of-pretreatment-strategies-on-the-properties-and-hydrolysis-of-brewers-spent-grain
#20
Rajeev Ravindran, Swarna Jaiswal, Nissreen Abu-Ghannam, Amit K Jaiswal
In this study, brewer's spent grain (BSG) was subjected to a range pretreatments to study the effect on reducing sugar yield. Glucose and xylose were found to be the predominant sugars in BSG. Brewers spent grain was high in cellulose (19.21g/100g of BSG) and lignin content (30.84g/100g of BSG). Microwave assisted alkali (MAA) pretreatment was found to be the most effective pretreatment for BSG, where the pretreatment was conducted at 400W for 60s. A maximum reducing yield was observed with high biomass loading (1g/10ml), cellulase (158...
June 12, 2017: Bioresource Technology
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