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https://www.readbyqxmd.com/read/28196604/addition-of-bioactive-glass-to-glass-ionomer-cements-effect-on-the-physico-chemical-properties-and-biocompatibility
#1
T De Caluwé, C W J Vercruysse, I Ladik, R Convents, H Declercq, L C Martens, R M H Verbeeck
OBJECTIVES: Glass ionomer cements (GICs) are a subject of research because of their inferior mechanical properties, despite their advantages such as fluoride release and direct bonding to bone and teeth. Recent research aims to improve the bioactivity of the GICs and thereby improve mechanical properties on the long term. In this study, two types of bioactive glasses (BAG) (45S5F and CF9) are combined with GICs to evaluate the physico-chemical properties and biocompatibility of the BAG-GIC combinations...
February 10, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28193866/the-ets-5-transcription-factor-regulates-activity-states-in-caenorhabditis-elegans-by-controlling-satiety
#2
Vaida Juozaityte, David Pladevall-Morera, Agnieszka Podolska, Steffen Nørgaard, Brent Neumann, Roger Pocock
Animal behavior is shaped through interplay among genes, the environment, and previous experience. As in mammals, satiety signals induce quiescence in Caenorhabditis elegans Here we report that the C. elegans transcription factor ETS-5, an ortholog of mammalian FEV/Pet1, controls satiety-induced quiescence. Nutritional status has a major influence on C. elegans behavior. When foraging, food availability controls behavioral state switching between active (roaming) and sedentary (dwelling) states; however, when provided with high-quality food, C...
February 13, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28174126/accuracy-of-asge-high-risk-criteria-in-evaluation-of-patients-with-suspected-common-bile-duct-stones
#3
Huiqin He, Chenfei Tan, Jiaguo Wu, Ning Dai, Weiling Hu, Yawen Zhang, Loren Laine, James Scheiman, John J Kim
BACKGROUND AND AIMS: Endoscopic retrograde cholangiopancreatography (ERCP) is recommended for patients considered high-risk for choledocholithiasis after biochemical testing and abdominal ultrasound. Our aim was to determine whether American Society for Gastrointestinal Endoscopy (ASGE) guidelines accurately select patients where the risk of ERCP is justified. METHODS: Consecutive patients hospitalized with suspected choledocholithiasis at Sir Run Run Shaw Hospital who received biochemical testing, abdominal ultrasound, and definitive testing for choledocholithiasis (magnetic resonance cholangiopancreatography (MRCP), endoscopic ultrasound (EUS), ERCP, intraoperative cholangiogram (IOC), common bile duct (CBD) exploration) were identified...
February 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28145960/the-2016-austrian-swiss-german-fellowship
#4
Andrea N Veljkovic, Mathew D Sewell, Simon C Mears, Eric W Edmonds
The Austrian-Swiss-German (ASG) Traveling Fellowship, which began in 1979, is an annual exchange of surgeons between the German-speaking countries of Austria, Switzerland, and Germany and the English-speaking countries of the United States, England, and Canada. In 2016, 4 fellows were chosen to participate in the fellowship, including Eric Edmonds from the University of California, San Diego; Simon Mears from the University of Arkansas for Medical Sciences; Mathew Sewell from the James Cook University in Middlesbrough, England; and Andrea Veljkovic from the University of British Columbia in Vancouver...
February 1, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28120155/selective-anti-scatter-grid-removal-during-coronary-angiography-and-pci-a-simple-and-safe-technique-for-radiation-reduction
#5
James R Roy, Philip Sun, Glenn Ison, Ananth M Prasan, Tom Ford, Andrew Hopkins, David R Ramsay, James C Weaver
Objectives The aim of this study was to quantify the radiation dose reduction during coronary angiography and percutaneous coronary intervention (PCI) through removal of the anti-scatter grid (ASG), and to assess its impact on image quality in adult patients with a low body mass index (BMI). Methods A phantom with different thicknesses of acrylic was used with a Westmead Test Object to simulate patient sizes and assess image quality. 129 low BMI patients underwent coronary angiography or PCI with or without the ASG in situ...
January 24, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28117034/interventional-eus-with-videos
#6
John T Maple, Rahul Pannala, Barham K Abu Dayyeh, Harry R Aslanian, Brintha K Enestvedt, Adam Goodman, Sri Komanduri, Michael Manfredi, Udayakumar Navaneethan, Mansour A Parsi, Zachary L Smith, Nirav Thosani, Shelby A Sullivan, Subhas Banerjee
No abstract text is available yet for this article.
January 20, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28103621/development-and-validation-of-a-training-module-on-the-use-of-acetic-acid-for-the-detection-of-barrett-s-neoplasia
#7
Fergus J Q Chedgy, Kesavan Kandiah, Hugh Barr, John De Caestecker, Simon Dwerryhouse, Balint Eross, Charles Gordon, Susi Green, Andy Li, James Brown, Gaius Longcroft-Wheaton, Pradeep Bhandari
Background and study aims Acetic acid chromoendoscopy (AAC) enhances the ability to correctly identify Barrett's neoplasia, and is increasingly used by both expert and nonexpert endoscopists. Despite its increasing use, there is no validated training strategy to achieve competence. The aims of our study were to develop a validated training tool in AAC-assisted lesion recognition, to assess endoscopists' baseline knowledge of AAC-assisted lesion recognition, and to evaluate the efficacy and impact of this training tool...
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28098904/identification-of-biomarkers-of-intrahepatic-cholangiocarcinoma-via-integrated-analysis-of-mrna-and-mirna-microarray-data
#8
Yaqing Chen, Dan Liu, Pengfei Liu, Yajing Chen, Huiling Yu, Quan Zhang
The present study aimed to identify potential therapeutic targets of intrahepatic cholangiocarcinoma (ICC) via integrated analysis of gene (transcript version) and microRNA (miRNA/miR) expression. The miRNA microarray dataset GSE32957 contained miRNA expression data from 16 ICC, 7 mixed type of combined hepatocellular‑cholangiocarcinoma (CHC), 2 hepatic adenoma, 3 focal nodular hyperplasia (FNH) and 5 healthy liver tissue samples, and 2 cholangiocarcinoma cell lines. In addition, the mRNA microarray dataset GSE32879 contained mRNA expression data from 16 ICC, 7 CHC, 2 hepatic adenoma, 5 FNH and 7 healthy liver tissue samples...
January 16, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28089029/guidelines-for-privileging-credentialing-and-proctoring-to-perform-gi-endoscopy
#9
Ashley L Faulx, Jenifer R Lightdale, Ruben D Acosta, Deepak Agrawal, David H Bruining, Vinay Chandrasekhara, Mohamad A Eloubeidi, Robert D Fanelli, Suryakanth R Gurudu, Loralee Kelsey, Mouen A Khashab, Shivangi Kothari, V Raman Muthusamy, Bashar J Qumseya, Aasma Shaukat, Amy Wang, Sachin B Wani, Julie Yang, John M DeWitt
No abstract text is available yet for this article.
February 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28071059/accuracy-of-asge-criteria-for-the-prediction-of-choledocholithiasis
#10
Jacobo Dib
I read with interest the article "Accuracy of ASGE criteria for the prediction of choledocholithiasis" by Nárvaez et al. Patients with suspicion of choledocholithiasis (CL) were categorized according to the American Society for Gastrointestinal Endoscopy (ASGE) recommendations. Those patients classified into high or intermediate-probability for CL underwent an endoscopic retrograde cholangiopancreatography (ERCP) without any further non-endoscopic biliary imaging modalities. In the ASGE recommendations for intermediate risk CL patients, they mention options for the evaluation of these patients including endoscopic ultrasound (EUS) and magnetic resonance cholangiography (MRC)...
January 10, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28065885/endoscopic-retrograde-cholangiopancreatography-with-ampullary-biopsy-vs-ercp-alone-a-matched-pairs-controlled-evaluation-of-outcomes-and-complications
#11
Sunil Dacha, Saurabh Chawla, Jai Eun Lee, Steven A Keilin, Qiang Cai, Field F Willingham
BACKGROUND AND AIMS: Biopsy of the ampulla of Vater may be performed to evaluate for ampullary adenomas, suspected ampullary tumors and immunohistological staining for autoimmune pancreatitis. Ampullary biopsies are commonly performed at the time of endoscopic retrograde cholangiopancreatography (ERCP). Due to the well-established complication rate following ERCP, the contribution of ampullary biopsy as a potential independent risk factor would require a controlled comparison. METHODS: A matched-pairs, case-control analysis was performed for patients undergoing ERCP with or without ampullary biopsy...
January 8, 2017: Gastroenterology Report
https://www.readbyqxmd.com/read/28051264/homogenization-versus-homogenization-free-method-to-measure-muscle-glycogen-fractions
#12
N Mojibi, M Rasouli
OBJECTIVE: The glycogen is extracted from animal tissues with or without homogenization using cold perchloric acid. Three methods were compared for determination of glycogen in rat muscle at different physiological states. MATERIALS AND METHODS: Two groups of five rats were kept at rest or 45 minutes muscular activity. The glycogen fractions were extracted and measured by using three methods. RESULTS: The data of homogenization method shows that total glycogen decreased following 45 min physical activity and the change occurred entirely in acid soluble glycogen (ASG), while AIG did not change significantly...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28046458/we-ab-207a-10-transmission-characteristics-of-a-two-dimensional-antiscatter-grid-prototype-for-cbct
#13
C Altunbas, B Kavanagh, M Miften
PURPOSE: Scattered radiation remains to be a major contributor to image quality degradation in CBCT. To address the scatter problem, a focused, 2D antiscatter grid (2DASG) prototype was designed, and fabricated using additive manufacturing processes. Its scatter and primary transmission properties were characterized using a linac mounted CBCT system. METHODS: The prototype 2DASG was composed of rectangular grid holes separated by tungsten septa, and has a grid pitch of 2...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025817/cost-effectiveness-of-metal-stents-in-relieving-obstructive-jaundice-in-patients-with-pancreatic-cancer
#14
J M Martinez, A Anene, T G K Bentley, M J Cangelosi, L M Meckley, J D Ortendahl, A J Montero
BACKGROUND: ASGE and ESGE guidelines recommend endoscopic metal stent placement for pancreatic carcinoma patients with biliary obstruction, and whose estimated life expectancy is greater than 6 months. Because median overall survival (OS) of metastatic pancreatic adenocarcinoma until recently has been less than 6 months, plastic biliary stents were preferentially placed rather than metal due to the greater upfront cost of the latter. Recent advances in the treatment of metastatic pancreatic cancer have extended median OS beyond the 6-month range...
December 27, 2016: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/27995197/eus-guided-biliary-drainage-or-enteroscopy-assisted-ercp-in-patients-with-surgical-anatomy-and-biliary-obstruction-an-international-comparative-study
#15
Mouen A Khashab, Mohamad H El Zein, Kaveh Sharzehi, Fernando P Marson, Oleh Haluszka, Aaron J Small, Yousuke Nakai, Do Hyun Park, Rastislav Kunda, Anthony Y Teoh, Irene Peñas, Manuel Perez-Miranda, Vivek Kumbhari, Schalk Van der Merwe, Everson L Artifon, Andrew S Ross
Background and study aims: How enteroscopy-assisted ERCP (e-ERCP) and endoscopic ultrasound-guided biliary drainage (EUS-BD) compare in patients with surgically altered upper gastrointestinal anatomy is currently unknown. The aims of this study were to compare efficacy and safety of both techniques and study predictors of these outcomes. Patients and methods: This was an international, multicenter comparative cohort study at 10 tertiary centers. Outcomes data included technical success (biliary access with cholangiography and stent placement [when indicated]), clinical success (resolution of biliary obstruction) and adverse events (AEs) (graded according to the ASGE lexicon)...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27993573/clinical-utility-of-a-precision-medicine-test-evaluating-outpatients-with-suspected-obstructive-coronary-artery-disease
#16
Joseph A Ladapo, Matt Budoff, David Sharp, Michael Zapien, Lin Huang, Bruce Maniet, Lee Herman, Mark Monane
BACKGROUND: Identifying patients with obstructive coronary artery disease can be challenging for primary care physicians. Advances in precision medicine may help augment clinical tools and redefine the paradigm for evaluating coronary artery disease in the outpatient setting. A blood-based age/sex/gene expression score (ASGES) incorporating key features of precision medicine has shown clinical validity with a 96% negative predictive value and 89% sensitivity in estimating a symptomatic patient's current likelihood of obstructive coronary artery disease...
December 16, 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27984170/autism-genes-are-selectively-targeted-by-environmental-pollutants-including-pesticides-heavy-metals-bisphenol-a-phthalates-and-many-others-in-food-cosmetics-or-household-products
#17
REVIEW
C J Carter, R A Blizard
The increasing incidence of autism suggests a major environmental influence. Epidemiology has implicated many candidates and genetics many susceptibility genes. Gene/environment interactions in autism were analysed using 206 autism susceptibility genes (ASG's) from the Autworks database to interrogate ∼1 million chemical/gene interactions in the comparative toxicogenomics database. Any bias towards ASG's was statistically determined for each chemical. Many suspect compounds identified in epidemiology, including tetrachlorodibenzodioxin, pesticides, particulate matter, benzo(a)pyrene, heavy metals, valproate, acetaminophen, SSRI's, cocaine, bisphenol A, phthalates, polyhalogenated biphenyls, flame retardants, diesel constituents, terbutaline and oxytocin, inter alia showed a significant degree of bias towards ASG's, as did relevant endogenous agents (retinoids, sex steroids, thyroxine, melatonin, folate, dopamine, serotonin)...
October 27, 2016: Neurochemistry International
https://www.readbyqxmd.com/read/27981542/extraction-of-glycogen-on-mild-condition-lacks-aig-fraction
#18
Z Ghafouri, M Rasouli
OBJECTIVE: Extraction of animal tissues with cold water or perchloric acid yields less glycogen than is obtained with hot-alkaline. Extraction with acid and alkaline gives two fractions, acid soluble (ASG) and insoluble glycogen (AIG). The aim of this work is to examine the hypothesis that not all liver glycogen is extractable by Tris-buffer using current techniques. MATERIALS AND METHODS: Rat liver was homogenized with Tris-buffer pH 8.3 and extracted for the glycogen fractions, ASG and AIG...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27942238/targeted-transplantation-of-mitochondria-to-hepatocytes
#19
Nidhi Gupta, Catherine H Wu, George Y Wu
BACKGROUND: Mitochondrial defects in hepatocytes can result in liver dysfunction and death. Hepatocytes have cell-surface asialoglycoprotein receptors (AsGRs) which internalize AsGs within endosomes. The aim of this study was to determine whether mitochondria could be targeted to hepatocytes by AsGR-mediated endocytosis. MATERIALS AND METHODS: An AsG, AsOR, was linked to polylysine to create a conjugate, AsOR-PL, and complexed with healthy and functional mitochondria (defined by normal morphology, cytochrome c assays, and oxygen-consumption rates)...
2016: Hepatic Medicine: Evidence and Research
https://www.readbyqxmd.com/read/27924368/a-quantitative-readability-analysis-of-patient-education-resources-from-gastroenterology-society-websites
#20
David R Hansberry, Sahil R Patel, Prateek Agarwal, Nitin Agarwal, Elizabeth S John, Ann M John, James C Reynolds
BACKGROUND AND AIMS: The lay public frequently access and rely on online information as a source of their medical knowledge. Many medical societies are unaware of national patient education material guidelines and subsequently fail to meet them. The goal of the present study was to evaluate the readability of patient education materials within the medical field of gastroenterology. METHODS: Two hundred fourteen articles pertaining to patient education materials were evaluated with ten well-established readability scales...
December 6, 2016: International Journal of Colorectal Disease
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