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Michaël Mulot, Baptiste Monsion, Sylvaine Boissinot, Maryam Rastegar, Sophie Meyer, Nicole Bochet, Véronique Brault
Aphid-transmitted plant viruses are a threat for major crops causing massive economic loss worldwide. Members in the Luteoviridae family are transmitted by aphids in a circulative and non-replicative mode. Virions are acquired by aphids when ingesting sap from infected plants and are transported through the gut and the accessory salivary gland (ASG) cells by a transcytosis mechanism relying on virus-specific receptors largely unknown. Once released into the salivary canal, virions are inoculated to plants, together with saliva, during a subsequent feeding...
2018: Frontiers in Microbiology
Mark D Balceniuk, Lauren Trakimas, Claudia Aghaie, Doran Mix, Khurram Rasheed, Matthew Seaman, Jennifer Ellis, Roan Glocker, Adam Doyle, Michael C Stoner
INTRODUCTION: Chronic kidney disease (CKD) is a predictor of poor outcomes for patients undergoing endovascular aortic aneurysm repair (EVAR). Anatomic severity grade (ASG) represents a quantitative mechanism for assessing anatomical suitability for endovascular aortic repair. Anatomic severity grade has been correlated with repair outcomes and resource utilization. The purpose of this study was to identify a novel renal perfusion metric as a way to assist ASG with predicting EVAR outcomes...
January 1, 2018: Vascular and Endovascular Surgery
Audrey H Calderwood, Lukejohn W Day, V Raman Muthusamy, James Collins, Ralph David Hambrick, Andrew S Brock, Nalini M Guda, Jonathan M Buscaglia, Bret T Petersen, Navtej S Buttar, Lauren G Khanna, Vladimir M Kushnir, Aparna Repaka, Nicolas A Villa, Glenn M Eisen
No abstract text is available yet for this article.
March 21, 2018: Gastrointestinal Endoscopy
Sachin Wani, Shahnaz Sultan, Bashar Qumseya, Jennifer Michalek, John Dewitt, Steven A Edmundowicz, Karen L Woods
No abstract text is available yet for this article.
April 2018: Gastrointestinal Endoscopy
Marietta Iacucci, Cristina Trovato, Marco Daperno, Oluseyi Akinola, David Greenwald, Seth A Gross, Arthur Hoffman, Jeffrey Lee, Brendan C Lethebe, Mark Lowerison, Jennifer Nayor, Helmut Neumann, Timo Rath, Silvia Sanduleanu, Prateek Sharma, Ralf Kiesslich, Subrata Ghosh, John R Saltzman
BACKGROUND: Prediction of histology of small polyps facilitates colonoscopic treatment. The aims of this study were: 1) to develop a simplified polyp classification, 2) to evaluate its performance in predicting polyp histology, and 3) to evaluate the reproducibility of the classification by trainees using multiplatform endoscopic systems. METHODS: In phase 1, a new simplified endoscopic classification for polyps - Simplified Identification Method for Polyp Labeling during Endoscopy (SIMPLE) - was created, using the new I-SCAN OE system (Pentax, Tokyo, Japan), by eight international experts...
March 23, 2018: Endoscopy
Stefanos Farfaras, Ninni Sernert, Lars Rostgard Christensen, Erling K Hallström, Jüri-Toomas Kartus
BACKGROUND: The long-term outcome after the treatment of subacromial impingement syndrome (SAIS) with either nonsurgical or surgical methods has not been thoroughly investigated. Hypothesis/Purpose: The purpose was to evaluate the long-term clinical outcome and the presence of rotator cuff injuries and osteoarthritis (OA) after the surgical and nonsurgical treatment of SAIS. The hypothesis was that, at a minimum 10 years after the initial treatment, patients who had undergone acromioplasty would have a better clinical outcome and run a lower risk of developing rotator cuff ruptures and OA as compared with those treated with physical therapy...
March 1, 2018: American Journal of Sports Medicine
Chencheng Feng, Yang Zhang, Minghui Yang, Minghong Lan, Bo Huang, Huan Liu, Yue Zhou
High oxygen tension caused by neovascularization in the microenvironment of intervertebral discs (IVDs) is associated with the pathogenesis of IVD degeneration (IDD). Pre-mRNAs undergo alternative splicing (AS) to produce structurally and functionally diverse mRNA and proteins. However, the precise role of high oxygen tension in IDD and the relationship between AS and high oxygen tension in disc cells remain unknown. To investigate the effect of high oxygen tension on disc cells, Affymetrix Rat Transcriptome Array 1...
February 28, 2018: International Journal of Molecular Medicine
Arvind J Trindade, David R Lichtenstein, Harry R Aslanian, Manoop S Bhutani, Adam Goodman, Joshua Melson, Udayakumar Navaneethan, Rahul Pannala, Mansour A Parsi, Amrita Sethi, Shelby Sullivan, Nirav Thosani, Guru Trikudanathan, Rabindra R Watson, John T Maple
No abstract text is available yet for this article.
March 2018: Gastrointestinal Endoscopy
Mona C Gjessing, Maria Aamelfot, William N Batts, Sylvie L Benestad, Ole B Dale, Even Thoen, Simon C Weli, James R Winton
Gill disease in Atlantic salmon, Salmo salar L., causes big losses in the salmon farming industry. Until now, tools to cultivate microorganisms causing gill disease and models to study the gill responses have been lacking. Here we describe the establishment and characterization of two cell lines from the gills of Atlantic salmon. Atlantic salmon gill cell ASG-10 consisted of cells staining for cytokeratin and e-cadherin and with desmosomes as seen by transmission electron microscopy suggesting the cells to be of epithelial origin...
2018: PloS One
Wenhua Jiang, Pengfei Liu, Xiaodong Li
The purpose of the present study was to explore the targets of forkhead box D3 (FOXD3) in lung cancer, and thus contribute to the diagnosis and therapy of the disease. The gene expression profile of GSE64513 was downloaded from the Gene Expression Omnibus database. The dataset contained 3 FOXD3 knockout A549 lung cancer cell samples and 3 normal A549 cell samples. The differentially expressed genes (DEGs) between the FOXD3-knockout and normal A549 cells were identified using the limma package in R. The alternative splicing genes (ASGs) in FOXD3-knockout samples were identified by Replicate Multivariate Analysis of Transcript Splicing software...
March 2018: Oncology Letters
Xiaodan Yang, Zhulong Hu, Shanshan Fan, Qiang Zhang, Yi Zhong, Dong Guo, Yali Qin, Mingzhou Chen
Stress granules (SGs) contain stalled messenger ribonucleoprotein complexes and are related to the regulation of mRNA translation. Picornavirus infection can interfere with the formation of SGs. However, the detailed molecular mechanisms and functions of picornavirus-mediated regulation of SG formation are not clear. Here, we found that the 2A protease of a picornavirus, EV71, induced atypical stress granule (aSG), but not typical stress granule (tSG), formation via cleavage of eIF4GI. Furthermore, 2A was required and sufficient to inhibit tSGs induced by EV71 infection, sodium arsenite, or heat shock...
February 7, 2018: PLoS Pathogens
Dayna S Early, Jenifer R Lightdale, John J Vargo, Ruben D Acosta, Vinay Chandrasekhara, Krishnavel V Chathadi, John A Evans, Deborah A Fisher, Lisa Fonkalsrud, Joo Ha Hwang, Mouen A Khashab, V Raman Muthusamy, Shabana F Pasha, John R Saltzman, Amandeep K Shergill, Brooks D Cash, John M DeWitt
No abstract text is available yet for this article.
February 2018: Gastrointestinal Endoscopy
Timur Alexeev, Brian Kavanagh, Moyed Miften, Cem Altunbas
PURPOSE: Scattered radiation remains to be a major cause of image quality degradation in Flat Panel Detector (FPD)-based Cone-beam computed tomography (CBCT). We have been investigating a novel two-dimensional antiscatter grid (2D-ASG) concept to reduce scatter intensity, and hence improve CBCT image quality. We present the first CBCT imaging experiments performed with the 2D-ASG prototype, and demonstrate its efficacy in improving CBCT image quality. METHODS: A 2D-ASG prototype with septa focused to x-ray source was additively manufactured from tungsten and mounted on a Varian TrueBeam CBCT system...
February 2018: Medical Physics
Joseph A Ladapo, Matthew J Budoff, David Sharp, Jane Z Kuo, Lin Huang, Bruce Maniet, Lee Herman, Mark Monane
BACKGROUND: Diagnosing obstructive coronary artery disease (CAD) is challenging in elderly adults, and current diagnostic approaches for CAD expose these individuals to risks from contrast dye and invasive procedures. DESIGN: A Registry to Evaluate Patterns of Care Associated with the Use of Corus CAD in Real World Clinical Care Settings (PRESET; NCT01677156), pragmatic clinical trial. SETTING: Community, 21 primary care practices. PARTICIPANTS: Of 566 stable, nonacute outpatients presenting with symptoms suggestive of obstructive CAD, the 176 who were aged 65 and older (median age 70, 61% female) were the current study participants...
February 2018: Journal of the American Geriatrics Society
(no author information available yet)
No abstract text is available yet for this article.
November 27, 2017: Metabolism: Clinical and Experimental
Marvin Ryou, Kenneth R McQuaid, Christopher C Thompson, Steven Edmundowic, Klaus Mergener
No abstract text is available yet for this article.
November 14, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Marvin Ryou, Kenneth R McQuaid, Christopher C Thompson, Steven Edmundowicz, Klaus Mergener
No abstract text is available yet for this article.
January 2018: Obesity Surgery
Marvin Ryou, Kenneth R McQuaid, Christopher C Thompson, Steven Edmundowicz, Klaus Mergener
No abstract text is available yet for this article.
January 2018: Surgical Endoscopy
Ankit Chhoda, Deepanshu Jain, Shashideep Singhal
Background: American Society of Gastrointestinal Endoscopy (ASGE) criteria is widely used to predict probability of choledocholithiasis among patients with symptomatic gallstone disease but does not take sex into consideration. Methods: The cohort study included patients who underwent either endoscopic retrograde cholangiopancreatography or intraoperative cholangiography for suspected choledocholithiasis at our medical center. Clinical, laboratory and radiological data were collected for each patient and used to stratify them based on the ASGE risk criteria for choledocholithiasis...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
Ching-Hua Lee, James M Kates, Bhaskar D Rao, Harinath Garudadri
This paper addresses trade-offs in adaptive feedback cancellation (AFC) for hearing aids. Aggressive AFC for improved added stable gain (ASG) reduces speech quality. In this paper, the hearing-aid speech quality index (HASQI) is used to investigate AFC performance before the system becomes unstable. It is demonstrated that for a desired speech quality, multiple AFC algorithms can be evaluated for their ASG and computational efficiency. An example is presented with HASQI = 0.8, baseline AFC, and two advanced approaches...
October 2017: Journal of the Acoustical Society of America
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