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Diastolic function, cardiac CT.

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https://www.readbyqxmd.com/read/28705554/atrial-function-atrial-volume-and-cardiovascular-clinical-outcomes-in-patients-with-end-stage-renal-disease-a-study-of-cardiac-computed-tomography
#1
Laust Dupont, Simon Winther, Hanne Skou Jørgensen, Peter Bomholt, Hans Erik Bøtker, Morten Bøttcher, Per Ivarsen, My Svensson
BACKGROUND: Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular events. Previous studies using 2-dimensional echocardiography show that left atrial end-diastolic volume (LAEDV) predicts cardiovascular outcomes and mortality in patients with CKD. However, contrast-enhanced cardiac CT may offers a more precise measure of atrial dimensions and function than 2-dimensional echocardiography and may provide improved predictionof patient outcome. AIM: The aim of the present study was to examine the association of LAEDV and left atrial ejection fraction (LAEF) assessed by CT with left ventricle end-diastolic volume (LVEDV), left ventricular mass, left ventricular ejection fraction and N-terminal plasma-pro-brain natriuretic peptide (NT-PRO-BNP)...
July 4, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28695406/quantification-of-intramyocardial-blood-volume-with-99m-tc-rbc-spect-ct-imaging-a-preclinical-study
#2
Hassan Mohy-Ud-Din, Nabil E Boutagy, John C Stendahl, Zhen W Zhuang, Albert J Sinusas, Chi Liu
BACKGROUND: Currently, there is no established non-invasive imaging approach to directly evaluate myocardial microcirculatory function in order to diagnose microvascular disease independent of co-existing epicardial disease. In this work, we developed a methodological framework for quantification of intramyocardial blood volume (IMBV) as a novel index of microcirculatory function with SPECT/CT imaging of (99m)Tc-labeled red blood cells (RBCs). METHODS: Dual-gated myocardial SPECT/CT equilibrium imaging of (99m)Tc-RBCs was performed on twelve canines under resting conditions...
July 10, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28673246/effects-of-ampd1-gene-c34t-polymorphism-on-cardiac-index-blood-pressure-and-prognosis-in-patients-with-cardiovascular-diseases-a-meta-analysis
#3
Ai-Fang Feng, Zhong-Hui Liu, Shu-Long Zhou, Shi-Yuan Zhao, Yan-Xin Zhu, Huai-Xin Wang
BACKGROUND: The meta-analysis was aimed to evaluate the effects of AMPD1 gene C34T polymorphism on cardiac function indexes, blood pressure and prognosis in patients with cardiovascular diseases (CVD). METHODS: Eligible studies were retrieved through a comprehensive search of electronic databases and manual search. Then the high-quality studies met the rigorous inclusion and exclusion criteria, as well as related to the subject was selected for the study. Comprehensive data analyses were conducted using STATA software 12...
July 3, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28670161/left-ventricular-functional-parameters-and-geometric-patterns-in-korean-adults-on-coronary-ct-angiography-with-a-320-detector-row-ct-scanner
#4
Eun-Ju Kang, Ki-Nam Lee, Won Jin Choi, Young-Dae Kim, Kyung Min Shin, Jae-Kwang Lim, Jongmin Lee
OBJECTIVE: To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. MATERIALS AND METHODS: This study retrospectively enrolled 172 subjects (107 men and 65 women; age, 58 ± 10.9 years; body surface area [BSA], 1.75 ± 0.2 m(2)) who underwent CCTA without any prior history of cardiac disease...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28650244/cardiac-output-measured-by-use-of-electrocardiogram-gated-64-slice-multidector-computed-tomography-echocardiography-and-thermodilution-in-healthy-dogs
#5
Nicole L LeBlanc, Katherine F Scollan, Susanne M Stieger-Vanegas
OBJECTIVE To evaluate the accuracy of cardiac output (CO) estimated by use of ECG-gated multidetector CT (MDCT) and 1-, 2-, and 3-D echocardiography and by use of thermodilution. ANIMALS 6 healthy hound-cross dogs. PROCEDURES Electrocardiogram-gated contrast-enhanced 64-slice MDCT and 1-, 2-, and 3-D echocardiography were performed on each dog. The CO for ECG-gated MDCT was calculated as volumetric measurements of stroke volume multiplied by mean heart rate. Echocardiographic left ventricle end-diastolic volumes and end-systolic volumes were measured by use of the Teichholz method (1-D echocardiography) and a single-plane method of disks (2-D echocardiography)...
July 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28631080/comparison-of-volumetric-and-functional-parameters-in-simultaneous-cardiac-pet-mr-feasibility-of-volumetric-assessment-with-residual-activity-from-prior-pet-ct
#6
C Lücke, B Oppolzer, P Werner, B Foldyna, P Lurz, T Jochimsen, B Brenneis, L Lehmkuhl, B Sattler, M Grothoff, H Barthel, O Sabri, M Gutberlet
OBJECTIVE: To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT. METHODS: Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9)...
June 19, 2017: European Radiology
https://www.readbyqxmd.com/read/28553096/pulmonary-artery-to-aorta-ratio-is-associated-with-cardiac-structure-and-functional-changes-in-mild-to-moderate-copd
#7
Michael J Cuttica, Surya P Bhatt, Sharon R Rosenberg, Lauren Beussink, Sanjiv J Shah, Lewis J Smith, Mark T Dransfield, Ravi Kalhan
BACKGROUND: The ratio of the diameter of the pulmonary artery (PA) to the diameter of the aorta (PA:A) on computed tomography (CT) imaging is associated with both COPD exacerbation and pulmonary hypertension. The mechanisms of PA enlargement in COPD are poorly understood. METHODS: In this retrospective, single center study we evaluated pulmonary function, CT scans, right heart catheterizations, and echocardiography in 88 subjects with mild-to-moderately severe COPD...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28550173/experimental-cardiac-radiation-exposure-induces-ventricular-diastolic-dysfunction-with-preserved-ejection-fraction
#8
Hirofumi Saiki, Gilles Moulay, Adam J Guenzel, Weibin Liu, Teresa Decklever, Kelly Classic, Linh Pham, Horng H Chen, John C Burnett, Stephen J Russell, Margaret M Redfield
BACKGROUND: Breast cancer radiotherapy increases the risk of heart failure (HF) with preserved ejection fraction (HFpEF). Cardiomyocytes are highly radio-resistant but radiation specifically affects coronary microvascular endothelial cells with subsequent microvascular inflammation and rarefaction. The effects of radiation on left ventricular (LV) diastolic function are poorly characterized. We hypothesized that cardiac radiation exposure may result in diastolic dysfunction without reduced EF...
May 26, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28497191/evaluation-of-the-coronary-circulation-and-calcification-in-children-on-regular-hemodialysis
#9
Mohammed Al-Biltagi, Maher Ahmed Abd ElHafez, Doaa Mohamed El Amrousy, Mohamed El-Gamasy, Hesham El-Serogy
BACKGROUND: The objective of this study was to evaluate the coronary circulation and calcification in children with end-stage renal disease (ESRD) on hemodialysis. METHODS: A total of 50 children with ESRD and 50 healthy controls were enrolled in the study. Cardiac functions and coronary blood flow were evaluated with conventional and tissue Doppler echocardiography. Coronary artery calcification (CAC) was evaluated using high-resolution multidetector computed tomography (CT)...
May 11, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28460004/4d-flow-cardiac-magnetic-resonance-derived-vorticity-is-sensitive-marker-of-left-ventricular-diastolic-dysfunction-in-patients-with-mild-to-moderate-chronic-obstructive-pulmonary-disease
#10
Michal Schäfer, Stephen Humphries, Kurt R Stenmark, Vitaly O Kheyfets, J Kern Buckner, Kendall S Hunter, Brett E Fenster
Aims: To investigate the possibility that vorticity assessed by four-dimensional flow cardiac magnetic resonance (4D-Flow CMR) in the left ventricle of patients with mild-to-moderate chronic obstructive pulmonary disease (COPD) is a potential marker of early LV diastolic dysfunction (LVDD) and more sensitive than standard echocardiography, and whether changes in vorticity are associated with quantitative computed tomography (CT) and clinical markers of COPD, and right ventricular (RV) echocardiographic markers indicative of ventricular interdependency...
April 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28435004/improvements-in-left-ventricular-diastolic-mechanics-after-parachute-device-implantation-in-patients-with-ischemia-heart-failure-a-cardiac-computerized-tomographic-study
#11
Chun-Ho Yun, Jing-Yi Sun, Barry Templin, Shih-Hsuan Lin, Kuan-Ming Chen, Tung-Hsin Wu, Chung-Lieh Hung, Chun-Chieh Liu, Hsi-Hsien Hsu, Mohamad Amer Alaiti, Anas Fares, Anthony DeCicco, Hiram G Bezerra
BACKGROUND: Percutaneous ventricular restoration therapy with the use of a left ventricle (LV)-partitioning Parachute device has emerged as a clinical treatment option for LV apical aneurysm after extensive anterior myocardial infarction (AMI). We assessed changes of diastolic mechanics and functional improvements following LV Parachute device implantation by means of cardiac computerized tomography (CCT). METHODS AND RESULTS: CCT data were obtained from 28 patients before and after LV Parachute device implantation...
June 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28426728/pulmonary-vascular-volume-impaired-left-ventricular-filling-and-dyspnea-the-mesa-lung-study
#12
Carrie P Aaron, Eric A Hoffman, Joao A C Lima, Steven M Kawut, Alain G Bertoni, Jens Vogel-Claussen, Mohammadali Habibi, Katja Hueper, David R Jacobs, Ravi Kalhan, Erin D Michos, Wendy S Post, Martin R Prince, Benjamin M Smith, Bharath Ambale-Venkatesh, Chia-Ying Liu, Filip Zemrak, Karol E Watson, Matthew Budoff, David A Bluemke, R Graham Barr
BACKGROUND: Evaluation of impaired left ventricular (LV) filling has focused on intrinsic causes of LV dysfunction; however, pulmonary vascular changes may contribute to reduced LV filling and dyspnea. We hypothesized that lower total pulmonary vascular volume (TPVV) on computed tomography (CT) would be associated with dyspnea and decrements in LV end-diastolic volume, particularly among ever-smokers. METHODS: The Multi-Ethnic Study of Atherosclerosis recruited adults without clinical cardiovascular disease in 2000-02...
2017: PloS One
https://www.readbyqxmd.com/read/28176968/decreased-left-ventricular-stroke-volume-is-associated-with-low-grade-exercise-tolerance-in-patients-with-chronic-obstructive-pulmonary-disease
#13
Sumito Inoue, Yoko Shibata, Hiroyuki Kishi, Joji Nitobe, Tadateru Iwayama, Yoshinori Yashiro, Takako Nemoto, Kento Sato, Masamichi Sato, Tomomi Kimura, Akira Igarashi, Yoshikane Tokairin, Isao Kubota
BACKGROUND: Low-grade exercise tolerance is associated with a poor prognosis in patients with chronic obstructive pulmonary disease (COPD). The 6 min walk test (6MWT) is commonly used to evaluate exercise tolerance in patients with COPD. However, little is known regarding the relationship between cardiac function and exercise tolerance in patients with COPD. The aim of this study was to identify predictive factors in cardiac function for low-grade exercise tolerance in patients with stable COPD...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28140622/exaggerated-interventricular-dependence-among-patients-with-pectus-excavatum-combined-assessment-with-cardiac-mri-and-chest-ct
#14
Alejandro Deviggiano, Javier Vallejos, Natalia Vina, Marcelo Martinez-Ferro, Gaston Bellia-Munzon, Patricia Carrascosa, Gaston A Rodríguez-Granillo
OBJECTIVE: We sought to explore whether patients with pectus excavatum have exaggerated interventricular dependence and to evaluate the impact of the malformation severity (assessed on CT) on both anatomic and functional cardiac parameters (assessed on cardiac MRI). SUBJECTS AND METHODS: The current study involved consecutive patients with a diagnosis of pectus excavatum who were referred to undergo cardiac MRI and chest CT to establish surgical candidacy or to define treatment strategies...
April 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28067199/computed-tomography-in-patients-with-tricuspid-regurgitation-prior-to-transcatheter-valve-repair-dynamic-analysis-of-the-annulus-with-an-individually-tailored-contrast-media-protocol
#15
Ricarda Hinzpeter, Matthias Eberhard, Philipp Burghard, Felix C Tanner, Maurizio Taramasso, Robert Manka, Gudrun Feuchtner, Francesco Maisano, Hatem Alkadhi
AIMS: The aim of this study is to present a contrast media (CM) protocol for the dynamic visualisation of the tricuspid valve (TV) and tricuspid annulus (TA) with CT. METHODS AND RESULTS: Fifteen patients with no cardiac abnormalities (controls), 15 patients with functional tricuspid regurgitation (FTR) <3+, and 13 patients with FTR ≥3+ underwent a dedicated cardiac CT protocol. Using advanced visualisation, segmentation and analysis software, the annular area, entire annular circumference, its three parts, and annular diameters were measured by two independent, blinded readers...
February 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28027742/prognostic-value-of-ct-derived-left-atrial-and-left-ventricular-measures-in-patients-with-acute-chest-pain
#16
Richard A P Takx, Rozemarijn Vliegenthart, U Joseph Schoepf, John W Nance, Fabian Bamberg, Joseph A Abro, Christine M Carr, Sheldon E Litwin, Paul Apfaltrer
PURPOSE: To determine which left atrial (LA) and left ventricular (LV) parameters are associated with future major adverse cardiac event (MACE) and whether these measurements have independent prognostic value beyond risk factors and computed tomography (CT)-derived coronary artery disease measures. MATERIALS AND METHODS: This retrospective analysis was performed under an IRB waiver and in HIPAA compliance. Subjects underwent coronary CT angiography (CCTA) using a dual-source CT system for acute chest pain evaluation...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/27730776/cardiac-diastolic-dysfunction-and-regional-body-fat-distribution-in-insulin-resistant-peripubertal-obese-males
#17
A V Sahasrabuddhe, S U Pitale, Dhoble, J Shivalkar, M M Sagdeo
BACKGROUND: To evaluate presence of diastolic dysfunction in obese peripubertal males (8-18 years of age). To correlate diastolic dysfunction with insulin resistance, insulin levels and omental and epicardial fat. METHODS: Obese males (n=46) and age matched healthy lean controls (n=50) in the age group of 8-18 years were included in this study. Anthropometric measurements were recorded. Investigations done: Fasting blood sugar and serum insulin levels, lipid profile, 2-D Echocardiography to assess left ventricular diastolic function and epicardial fat, abdominal CT scan to measure omental fat and ultrasound for NAFLD...
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27589871/three-dimensional-echocardiography-in-various-types-of-heart-disease-a-comparison-study-of-magnetic-resonance-imaging-and-64-slice-computed-tomography-in-a-real-world-population
#18
Angelo Squeri, Stefano Censi, Claudio Reverberi, Nicola Gaibazzi, Marco Baldelli, Simone Maurizio Binno, Enrico Properzi, Stefano Bosi
BACKGROUND: Accurate quantification of left ventricular (LV) volumes [end-diastolic volume (EDV) and end-systolic volume (ESV)] and ejection fraction (EF) is of critical importance. The development of real-time three-dimensional echocardiography (RT3DE) has shown better correlation than two-dimensional (2D) echocardiography with magnetic resonance imaging (MRI) measurements. The aim of our study was to assess the accuracy of RT3DE and 64-slice computed tomography (CT) in the evaluation of LV volumes and function using MRI as the reference standard in a real-world population with various types of heart disease with different chamber geometry...
March 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/27577518/patient-related-factors-that-influence-coronary-artery-density-in-ccta-a-retrospective-clinical-study
#19
Peng Cao, Miao He, Chen Qiao, Nan Xu, Daoyi Huang, Gonghua Dai, Yibin Wang, Haihong Pan, Lei Zhang
OBJECTIVES: The aim of this study was to investigate the relationship between various patient-related factors (physical and cardiac hemodynamic parameters) and the coronary artery density on coronary CT angiography (CCTA). METHODS: A total of 64 patients (female: male ratio, 24:40; age, 58.2 years±9.3, age range, 31-81 years; mean body weight, 65.3 kg±11.6, range 40-88 kg) were effectively enrolled in this approved retrospective study. Patient-related physical factors including height, body weight (BW), body mass index (BMI), systolic blood pressure (BPsys), diastolic blood pressure (BPdis) and blood pulse pressure (Bp) were recorded, measured and calculated prior to the administration of contrast media during the CCTA...
September 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27461207/impact-of-age-and-sex-on-left-ventricular-function-determined-by-coronary-computed-tomographic-angiography-results-from-the-prospective-multicentre-confirm-study
#20
Catherine Gebhard, Ronny R Buechel, Barbara E Stähli, Heidi Gransar, Stephan Achenbach, Daniel S Berman, Matthew J Budoff, Tracy Q Callister, Benjamin Chow, Allison Dunning, Mouaz H Al-Mallah, Filippo Cademartiri, Kavitha Chinnaiyan, Ronen Rubinshtein, Hugo Marques, Augustin DeLago, Todd C Villines, Martin Hadamitzky, Joerg Hausleiter, Leslee J Shaw, Ricardo C Cury, Gudrun Feuchtner, Yong-Jin Kim, Erica Maffei, Gilbert Raff, Gianluca Pontone, Daniele Andreini, Hyuk-Jae Chang, Jonathon Leipsic, James K Min, Philipp A Kaufmann
BACKGROUND: Left ventricular (LV) volumetric and functional parameters measured with cardiac computed tomography (cardiac CT) augment risk prediction and discrimination for future mortality. Gender- and age-specific standard values for LV dimensions and systolic function obtained by 64-slice cardiac CT are lacking. METHODS AND RESULTS: 1155 patients from the Coronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter registry (54.5% males, mean age 53...
July 26, 2016: European Heart Journal Cardiovascular Imaging
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