Read by QxMD icon Read


Hoang Minh Tue Nguyen, Andrew T Gabrielson, Wayne J G Hellstrom
INTRODUCTION: Erectile dysfunction (ED) is an important health concern that can significantly affect a man's psychosocial well-being. ED has traditionally been considered a disease of old age; however, contemporary evidence suggests a growing incidence of ED in men younger than 40 years. The process of achieving an erection is multifaceted; there are many potential mechanisms that can be disrupted. It is critical to identify the specific causes of ED before proceeding with potentially costly and invasive therapeutic options...
June 19, 2017: Sexual Medicine Reviews
Andrew T Gabrielson, Jonathan T Spitz, Wayne J G Hellstrom
INTRODUCTION: Peyronie's disease (PD) is a connective tissue disorder resulting in the abnormal accumulation of type I to III collagen, fibrin, and disorganized elastic fibers in the tunica albuginea of the penis. Many medical and non-pharmacologic modalities have been used in the treatment of PD; however, these approaches have proved largely ineffective, with surgery being the only definitive treatment. Intralesional injection of collagenase Clostridium histolyticum (CCH) has recently become the gold standard for minimally invasive treatment of PD, and studies have suggested the role of CCH could expand to the treatment of other urologic conditions such as urethral stricture disease...
April 25, 2017: Sexual Medicine Reviews
Bruno T Saragiotto, Christopher G Maher, Tiê P Yamato, Leonardo O P Costa, Luciola C Menezes Costa, Raymond W J G Ostelo, Luciana G Macedo
STUDY DESIGN: A systematic review. OBJECTIVE: The aim of this review was to evaluate the effectiveness of motor control exercise (MCE) in patients with nonspecific low back pain (LBP). SUMMARY OF BACKGROUND DATA: MCE is a common form of exercise used for managing LBP. MCE focuses on the activation of the deep trunk muscles and targets the restoration of control and coordination of these muscles, progressing to more complex and functional tasks integrating the activation of deep and global trunk muscles...
August 15, 2016: Spine
Luciana G Macedo, Bruno T Saragiotto, Tiê P Yamato, Leonardo O P Costa, Luciola C Menezes Costa, Raymond W J G Ostelo, Christopher G Maher
BACKGROUND: Motor control exercise (MCE) is used by healthcare professionals worldwide as a common treatment for low back pain (LBP). However, the effectiveness of this intervention for acute LBP remains unclear. OBJECTIVES: To evaluate the effectiveness of MCE for patients with acute non-specific LBP. SEARCH METHODS: We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), four other databases and two trial registers from their inception to April 2015, tracked citations and searched reference lists...
2016: Cochrane Database of Systematic Reviews
Tiê P Yamato, Christopher G Maher, Bruno T Saragiotto, Mark J Hancock, Raymond W J G Ostelo, Cristina M N Cabral, Luciola C Menezes Costa, Leonardo O P Costa
STUDY DESIGN: Systematic review. OBJECTIVE: To determine the effects of the Pilates method for patients with nonspecific acute, subacute, or chronic low back pain. SUMMARY OF BACKGROUND DATA: The Pilates method is one of the most common forms of intervention based on exercise used for treating patients with low back pain. However, its effectiveness is not well established. METHODS: We conducted searches on CENTRAL, MEDLINE, EMBASE, CINAHL, PEDro, and SPORTDiscus up to March 2014...
June 2016: Spine
Faysal A Yafi, Georgios Hatzichristodoulou, Christopher J Knoedler, Landon W Trost, Suresh C Sikka, Wayne J G Hellstrom
INTRODUCTION: Approximately 10% of Peyronie's disease (PD) patients present with ventral curvatures and, as such, there is a paucity of data describing the optimal approach for treatment. AIM: This study aims to compare the outcomes of surgery (tunical plication [TP]) and intralesional injection (ILI) therapy (interferon-α2b) in men with ventral PD. MATERIALS AND METHODS: Retrospective data were collected from two centers: Tulane University (ILI) and Technical University of Munich (TP)...
December 2015: Journal of Sexual Medicine
A S de Jong, J C Rahamat-Langendoen, Ptw van Alphen, N Hilt, Cmc van Herk, Sbeh Pont, Wjg Melchers, Jhb van de Bovenkamp
Mycoplasma genitalium and Trichomonas vaginalis are common sexually transmitted infections (STIs). In the Netherlands, testing for M. genitalium and T. vaginalis is not recommended for first-line STI screening. Recent reports about the increasing antimicrobial resistance in M. genitalium raise concern about the adequacy of current empirical treatment regimens. It is necessary to have insight in the prevalence of M. genitalium and T. vaginalis in order to evaluate current first-line STI screening and treatment protocols...
September 2016: International Journal of STD & AIDS
R M F Ebisch, M M Rovers, R P Bosgraaf, H W van der Pluijm-Schouten, W J G Melchers, P A J van den Akker, L F A G Massuger, R L M Bekkers
BACKGROUND: Studies of see-and-treat management of cervical intraepithelial neoplasia (CIN) vary in their inclusion criteria, resulting in a broad range of overtreatment rates. OBJECTIVES: To determine overtreatment rates in see-and-treat management of women referred for colposcopy because of suspected CIN, in order to define circumstances supporting see-and-treat management. SEARCH STRATEGY: MEDLINE, EMBASE, and the Cochrane Library were searched from inception up to 12 May 2014...
January 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Tiê P Yamato, Christopher G Maher, Bruno T Saragiotto, Mark J Hancock, Raymond W J G Ostelo, Cristina M N Cabral, Luciola C Menezes Costa, Leonardo O P Costa
BACKGROUND: Non-specific low back pain is a major health problem worldwide. Interventions based on exercises have been the most commonly used treatments for patients with this condition. Over the past few years, the Pilates method has been one of the most popular exercise programmes used in clinical practice. OBJECTIVES: To determine the effects of the Pilates method for patients with non-specific acute, subacute or chronic low back pain. SEARCH METHODS: We conducted the searches in CENTRAL, MEDLINE, EMBASE, CINAHL, PEDro and SPORTDiscus from the date of their inception to March 2014...
July 2, 2015: Cochrane Database of Systematic Reviews
John D Dean, Chris G McMahon, Andre T Guay, Abraham Morgentaler, Stanley E Althof, Edgardo F Becher, Trinity J Bivalacqua, Arthur L Burnett, Jacques Buvat, Amr El Meliegy, Wayne J G Hellstrom, Emmanuele A Jannini, Mario Maggi, Andrew McCullough, Luiz Otavio Torres, Michael Zitzmann
INTRODUCTION: In 2014, the International Society for Sexual Medicine (ISSM) convened a panel of experts to develop an evidence-based process of care for the diagnosis and management of testosterone deficiency (TD) in adult men. The panel considered the definition, epidemiology, etiology, physiologic effects, diagnosis, assessment and treatment of TD. It also considered the treatment of TD in special populations and commented on contemporary controversies about testosterone replacement therapy, cardiovascular risk and prostate cancer...
August 2015: Journal of Sexual Medicine
Tsjitske M Haanstra, Steven J Kamper, Christopher M Williams, Alette S Spriensma, Chung-Wei Christine Lin, Christopher G Maher, Henrica C W de Vet, Raymond W J G Ostelo
It is believed that patients' expectancies about the effectiveness of treatment influence their treatment outcomes, but the working mechanism is rarely studied in patients with low back pain. Theoretical models suggest that adherence to treatment may be an important pathway. The aim of this study was to assess the mediating role of adherence to treatment in the relationship between expectancies and the outcomes of recovery and pain intensity in patients with acute low back pain. This study used data from a randomized placebo-controlled trial of paracetamol for acute low back pain...
August 2015: Pain
Helge Franke, Gary Fryer, Raymond W J G Ostelo, Steven J Kamper
BACKGROUND: Low-back pain (LBP) is responsible for considerable personal suffering due to pain and reduced function, as well as the societal burden due to costs of health care and lost work productivity. For the vast majority of people with LBP, no specific anatomical cause can be reliably identified. For these people with non-specific LBP there are numerous treatment options, few of which have been shown to be effective in reducing pain and disability. The muscle energy technique (MET) is a treatment technique used predominantly by osteopaths, physiotherapists and chiropractors which involves alternating periods of resisted muscle contractions and assisted stretching...
February 27, 2015: Cochrane Database of Systematic Reviews
Gerben Meynen, Heleen Van Stralen, Jan H Smit, Wouter Kamphorst, Dick F Swaab, Witte J G Hoogendijk
UNLABELLED: Meynen G, Van Stralen H, Smit JH, Kamphorst W, Swaab DF, Hoogendijk WJG. Relation between neuritic plaques and depressive state in Alzheimer's disease. BACKGROUND: To investigate for the first time in a prospective study the relationship between depressive state and the neuropathological hallmarks of Alzheimer's disease, using a scale for depressive symptoms in dementia, while controlling for clinical severity of dementia. METHOD: Within the framework of a prospective longitudinal study of depression in Alzheimer's disease, patients with dementia underwent a clinical evaluation every six months during the last years of their lives, using the Cornell scale for depression in dementia to assess depressive symptoms and using the Functional Assessment Staging scale to control for clinical severity of dementia...
February 2010: Acta Neuropsychiatrica
Stanley E Althof, Chris G McMahon, Marcel D Waldinger, Ege Can Serefoglu, Alan W Shindel, P Ganesan Adaikan, Edgardo Becher, John Dean, Francois Giuliano, Wayne Jg Hellstrom, Annamaria Giraldi, Sidney Glina, Luca Incrocci, Emmanuele Jannini, Marita McCabe, Sharon Parish, David Rowland, R Taylor Segraves, Ira Sharlip, Luiz Otavio Torres
INTRODUCTION: In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year...
June 2014: Sexual Medicine
Ege Can Serefoglu, Chris G McMahon, Marcel D Waldinger, Stanley E Althof, Alan Shindel, Ganesh Adaikan, Edgardo F Becher, John Dean, Francois Giuliano, Wayne Jg Hellstrom, Annamaria Giraldi, Sidney Glina, Luca Incrocci, Emmanuele Jannini, Marita McCabe, Sharon Parish, David Rowland, R Taylor Segraves, Ira Sharlip, Luiz Otavio Torres
INTRODUCTION: The International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature Ejaculation developed the first evidence-based definition for lifelong premature ejaculation (PE) in 2007 and concluded that there were insufficient published objective data at that time to develop a definition for acquired PE. AIM: The aim of this article is to review and critique the current literature and develop a contemporary, evidence-based definition for acquired PE and/or a unified definition for both lifelong and acquired PE...
June 2014: Sexual Medicine
Hua Yang, Yun-Xiang Chen
AIM: To understand the changes and development of World Journal of Gastroenterology (WJG) in recent years. METHODS: The Journal Citation Report (JCR) and SCI-E database of the ISI Web of Knowledge were used to search the articles and data of related indices in WJG during 2008-2012. Bibliometric methods were used for statistical analysis of the author's degree of collaboration, collaboration rate, the first author's publications, high-productivity authors, the authors' origins in each year; the distribution of the countries and journals of the authors citing WJG papers was also analyzed...
November 28, 2013: World Journal of Gastroenterology: WJG
Ege Can Serefoglu, Sree Harsha Mandava, Ahmet Gokce, Jyoti D Chouhan, Steve K Wilson, Wayne J G Hellstrom
Introduction.  Penile implant surgery continues to be an important option for men with erectile dysfunction. Advancements in technology of implants have contributed to improved survival from mechanical breakdown. Prosthesis infection remains a serious adverse event. For the last 8 years, the Titan implant (Coloplast Corporation, Minneapolis, MN, USA) has been available with an infection-retardant polyvinylpyrrolidone coating. Aim.  To compare the infection rates between coated three-piece inflatable penile prostheses (IPPs) with the previous non-coated model...
August 2012: Journal of Sexual Medicine
Alessandro Sciarra
The authors analysed the potential use and limitations of carbonic anhydrase IX (CAIX) antigen as a marker with diagnostic and prognostic value in cases of clear-cell renal cell carcinoma (ccRCC). The study reports that >95% of ccRCCs show high and homogeneous levels of CAIX expression by reverse transcription-polymerase chain reaction and immunohistochemistry. Monoclonal antibody (MAb) G250 has a high affinity for the CAIX antigen. Using MAb G250 in iodine 131-G250 radioimmunoscintigraphy (RIS) and fluorodeoxyglucose F 18 positron emission tomography (PET) can detect primary ccRCC and metastatic sites through the affinity with CAIX antigen...
August 2010: European Urology
Nicholas Henschke, Raymond Wjg Ostelo, Maurits W van Tulder, Johan Ws Vlaeyen, Stephen Morley, Willem Jj Assendelft, Chris J Main
BACKGROUND: Behavioural treatment is commonly used in the management of chronic low-back pain (CLBP) to reduce disability through modification of maladaptive pain behaviours and cognitive processes. Three behavioural approaches are generally distinguished: operant, cognitive, and respondent; but are often combined as a treatment package. OBJECTIVES: To determine the effects of behavioural therapy for CLBP and the most effective behavioural approach. SEARCH STRATEGY: The Cochrane Back Review Group Trials Register, CENTRAL, MEDLINE, EMBASE, and PsycINFO were searched up to February 2009...
2010: Cochrane Database of Systematic Reviews
Guang-An Zu
Supported by the "Special Fund for Key Academic Journals" of the National Natural Science Foundation of China, World Journal of Gastroenterology (WJG) has become a high-impact international clinical medical journal due to the great efforts of Professor Lian-Sheng Ma, Editor-in-Chief, and his team over several years. Now, WJG has successfully achieved a high degree of internationalization and sets a good example for other Chinese academic journals.
June 14, 2010: World Journal of Gastroenterology: WJG
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"