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Aneurysmal bone cyst

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https://www.readbyqxmd.com/read/28211081/h3f3a-mutation-in-giant-cell-tumour-of-the-bone-is-detected-by-immunohistochemistry-using-a-monoclonal-antibody-against-the-g34w-mutated-site-of-the-histone-h3-3-variant
#1
Julian Lüke, Alexandra von Baer, Jordan Schreiber, Christoph Lübbehüsen, Thomas Breining, Kevin Mellert, Ralf Marienfeld, Markus Schultheiss, Peter Möller, Thomas Fe Barth
AIMS: Giant cell tumour of bone (GCTB) is a neoplasm predominantly of long bones characterised by the H3F3A mutation G34W. Conventional diagnostic is challenged by the tumour's giant cell-rich morphology, which overlaps with other giant cell containing lesions of the bone. Recently, a monoclonal antibody specific for the H3F3A mutation has been generated. Our aim was to test this antibody on a cohort of giant cell containing lesions. METHODS AND RESULTS: We used the antibody for analysis of 22 H3F3A-mutated GCTB, including two patients with recurrences; for comparison we analysed a cohort of 36 H3F3A-wild-type giant cell-rich lesions of the bone and soft tissue, containing one brown tumour, six aneurysmal bone cysts, six chondroblastomas, five non-ossifying-fibromas, two fibrous dysplasias, nine tenosynovial giant cell tumours, one giant cell-rich sarcoma and six osteosarcomas...
February 17, 2017: Histopathology
https://www.readbyqxmd.com/read/28208959/secondary-aneurysmal-bone-cyst-of-the-scapula-treated-by-ct-guided-percutaneous-polidocanol-injection-a-case-report
#2
Rahul Mohan, Gopakumar Thanuvan Sreekumaran
Aneurysmal Bone Cyst (ABC) is a rare benign tumour, usually affecting early age group and at the metaphysis of long bones. Scapular ABC's are even more rare, especially successfully treated cases. Standard treatment methods like curettage have high recurrence rates hence, adjuvant therapy may be required to avoid recurrence. Polidocanol sclerotherapy is becoming popular because of its safety and efficacy and is being tried successfully for both active as well as aggressive primary ABC of size 3-5cm. We used the same principle in a large secondary ABC of the scapula, which to the best of our knowledge has not been yet reported...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28195259/telangiectatic-osteosarcoma-of-the-rib-a-rare-entity-and-a-potential-diagnostic-pitfall
#3
I Saguem, L Ayadi, R Kallel, S Charfi, I Bahri, N Gouiaa, T Sellami-Boudawara
Osteosarcoma (OS) is a common primary malignant tumor of bones that produces osteoid matrix. Telangiectatic osteosarcoma (TOS) is a rare variant of OS. It affects the long bones especially the lower end of femur and the upper ends of tibia and humerus, a distribution similar to the conventional osteosarcoma. The rib involvement is very infrequent. We present a case of TOS of the rib that posed a diagnostic difficulty owing to its unusual location and to its resemblance to giant cell tumor and aneurysmal bone cyst...
December 2016: Pathologica
https://www.readbyqxmd.com/read/28193096/dedifferentiated-liposarcoma-of-the-retroperitoneum-with-heterologous-osteosarcomatous-differentiation-and-a-striking-aneurysmal-bone-cyst-like-morphology
#4
Carole Van Haverbeke, Jo Van Dorpe, Evelyne Lecoutere, Uta Flucke, Liesbeth Ferdinande, David Creytens
A 69-year-old woman with a 10-year medical history of recurrent retroperitoneal dedifferentiated liposarcoma presented with a 3-cm large hemorrhagic and multicystic left-sided retroperitoneal mass. Histopathological examination of the resected specimen showed a heterogeneous, high-grade mesenchymal nonlipogenic tumor with areas of osteoblastic/osteosarcomatous differentiation and aneurysmal bone cyst-like features. Based on the clinical presentation, the morphology, and the supportive immunohistochemical and molecular findings (MDM2 overexpression and amplification of the MDM2 gene, respectively), a diagnosis of a dedifferentiated liposarcoma with heterologous osteosarcomatous differentiation and an aneurysmal bone cyst-like morphology was made...
February 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28183835/benign-spine-lesions-advances-in-techniques-for-minimally-invasive-percutaneous-treatment
#5
REVIEW
A Tomasian, A N Wallace, J W Jennings
Minimally invasive percutaneous imaging-guided techniques have been shown to be safe and effective for the treatment of benign tumors of the spine. Techniques available include a variety of tumor ablation technologies, including radiofrequency ablation, cryoablation, microwave ablation, alcohol ablation, and laser photocoagulation. Vertebral augmentation may be performed after ablation as part of the same procedure for fracture stabilization or prevention. Typically, the treatment goal in benign spine lesions is definitive cure...
February 9, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28168344/aneurysmal-bone-cyst-of-the-spine-treated-by-concentrated-bone-marrow-clinical-cases-and-review-of-the-literature
#6
Giovanni Barbanti-Brodano, Marco Girolami, Riccardo Ghermandi, Silvia Terzi, Alessandro Gasbarrini, Stefano Bandiera, Stefano Boriani
PURPOSE: ABC is a benign lesion with unpredictable behavior. Its treatment is challenging, especially in poorly accessible surgical areas, such as spine and pelvis. Currently, the first-line treatment of ABC is repeated selective arterial embolization (SAE) until healing. Other options have been used with variable success rates. We propose an alternative treatment for spine aneurysmal bone cyst (sABC) based on the injection of concentrated autologous bone marrow. METHODS: We retrospectively report and analyze here two cases of patients, a 14-year-old girl and a 16-year-old boy, both affected by ABC in C2 vertebra which were impossible to treat by SAE...
February 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28164063/pathological-fracture-of-calcaneum-a-case-report
#7
K Salauddin Arif, S Anoop, Sandeep Ravindran
INTRODUCTION: Aneurysmal bone cysts (ABCs) are blood filled fibrous tumor-like cysts that expand the bone giving it a blown out appearance. It is usually seen in the second decade. ABCs were first described by Jaffe and Litchensen in 1942. The exact etiology is unknown. One of the most widely accepted ideas was that aneurysmal bone cyst was a consequence of increased venous pressure and subsequent dilatation and rupture of the local vascular network. However, studies by Panoutsakopoulus et al...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28092970/surgery-of-anterior-skull-base-lesions-in-children
#8
Thomas Karl Hoffmann, Marc Oliver Scheithauer, Fabian Sommer, Jörg Lindemann, Ernst-Johannes Haberl, Ulrike Friebe-Hoffmann, Marie-Nicole Theodoraki
INTRODUCTION: Lesions affecting the anterior skull base represent a rare group of craniofacial pathologies. A tumor of the facial midline, meningitis, or rhinoliquorrhea may be indicative of malformations like dermoid cysts, gliomas, encephaloceles, or nasal fistulas. METHODS: We present a case series of 13 children (4 months to 12 years; 8 males, 5 females) with lesions involving the anterior skull base, which were treated surgically in an interdisciplinary setting...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28068262/associated-aneurysmal-bone-cyst-and-cemento-osseous-dysplasia-a-case-report-and-review-of-the-literature
#9
Willian Pecin Jacomacci, João Paulo Veloso Perdigão, Vanessa Cristina Veltrini, Gustavo Jacobucci Farah, Elen Souza Tolentino, Lilian Cristina Vessoni Iwaki, Liogi Iwaki Filho
The purpose of this case report is to describe a previously unpublished association between focal cemento-osseous dysplasia (FCOD) and an aneurysmal bone cyst (ABC) and review the literature with regard to associated benign fibro-osseous lesions and cysts. A 41-year-old woman without a history of trauma presented with asymptomatic swelling in the right side of the mandible. Radiographs of the region revealed a unilocular radiolucent area with radiopaque foci. After aspiration of the lesion was positive for serosanguineous fluid, complete excision of the lesion was performed...
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28033191/a-giant-aneurysmal-bone-cyst-in-the-mandibular-condyle
#10
Kunjie Liu, Chuanbin Guo, Rui Guo, Juanhong Meng
Aneurysmal bone cyst (ABC) is a rare, rapidly expanding, locally destructive, and easily misdiagnosed lesion. An ABC of the condyle is rare. This report presents a 25-year-old female with a giant ABC in the left mandibular condyle. This patient was treated with surgical resection of the affected bone and immediate mandibular reconstruction using autologous bone. Follow-up to date showed no signs of recurrence. The clinical feature, imaging finding, pathogenesis, and treatment methods of ABCs are discussed.
December 28, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28018833/aneurysmal-bone-cyst-arising-from-the-first-rib-a-rare-cause-of-thoracic-outlet-syndrome
#11
Manuel Medina, Subroto Paul
Aneurysmal bone cyst is a rare benign cystic bone lesion with an incidence of only 0.14 per 100,000 individuals and most commonly affects the metaphyses of long bones, spine, and pelvis. We present a very rare case of a 17-year-old boy with a rapidly expanding aneurysmal bone cyst arising from the first rib, resulting in neurogenic thoracic outlet syndrome secondary to its compression of the brachial plexus. The patient's symptoms resolved after en bloc resection. To our knowledge there have been no other reports in the literature of thoracic outlet syndrome due to aneurysmal bone cyst arising from the first rib...
December 2016: Thoracic and Cardiovascular Surgeon Reports
https://www.readbyqxmd.com/read/28009802/benign-osteolytic-lesions-in-children-with-previously-normal-radiographs
#12
Emily Tan, Charles T Mehlman, Michael Baker
BACKGROUND: Benign bone tumors are common in children and are usually diagnosed incidentally or after pathologic fractures. However, case reports of children with lytic lesions with previously normal radiographs are rare. This series presents several such cases. METHODS: This was a retrospective case series of 8 benign osteolytic lesions in 8 pediatric patients (5 female and 3 males). All have previous radiographs of the effected extremity showing no pathology. All participants were at a single institution...
December 22, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28009753/efficacy-and-safety-of-selective-arterial-embolization-in-the-treatment-of-aneurysmal-bone-cyst-of-the-mobile-spine-a-retrospective-observational-study
#13
Silvia Terzi, Alessandro Gasbarrini, Mario Fuiano, Giovanni Barbanti Brodano, Riccardo Ghermandi, Stefano Bandiera, Stefano Boriani
STUDY DESIGN: Retrospective observational study. OBJECTIVE: Our aim is to define the efficacy and safety of serial selective arterial embolization (SAE) in the treatment of aneurysmal bone cysts, to explore potential treatment alternatives and to define a therapeutic algorithm. SUMMARY OF BACKGROUND DATA: Aneurysmal bone cyst (ABC) is a benign lesion with unpredictable behavior. Its treatment is challenging especially in poorly accessible surgical areas, such as spine and pelvis...
December 22, 2016: Spine
https://www.readbyqxmd.com/read/28003165/exceptional-rare-giant-craniofacial-chondroid-tumor-in-adult
#14
Si Zhang, Bangsheng Jia, Hao Li, Chao You
We present a rare case of giant soap bubble-shaped cystic lesion in the craniofacial region in an adult female. Histopathologic examination revealed the tumor consisted of 3 components including chondroblastoma, chondromyxoid fibroma, and hemorrhagic aneurysmal bone cyst. The present case is rare in terms of size, location, and histopathologic diagnosis, which is probably the result of underdeveloped health care in the remote place.
December 18, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27994691/giant-cell-tumor-with-secondary-aneurysmal-bone-cyst-shows-heterogeneous-metabolic-pattern-on-18-f-fdg-pet-ct-a-case-report
#15
Hee Jeong Park, Seong Young Kwon, Sang-Geon Cho, Jahae Kim, Ho-Chun Song, Sung Sun Kim, Yeon Hong Yoon, Jin Gyoon Park
Giant cell tumor (GCT) is a generally benign bone tumor accounting for approximately 5 % of all primary bone neoplasms. Cystic components in GCTs that indicate secondary aneurysmal bone cysts (ABCs) are reported in 14 % of GCTs. Although both of them have been described separately in previous reports that may show considerable fluorodeoxyglucose (FDG) uptake despite their benign nature, the findings of GCT with secondary ABC on (18)F-FDG positron emission tomography/computed tomography (PET/CT) have not been well-known...
December 2016: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27980757/aneurysmal-bone-cyst-of-the-mandible-affecting-the-articular-condyle-a-case-report
#16
Ana Belén Marín Fernández, Blas García Medina, Adoración Martínez Plaza, Antonio Aguilar-Salvatierra, Gerardo Gómez-Moreno
Aneurysmal bone cyst (ABC) is a benign osteolytic lesion that is fast-growing, expansile, and locally destructive. The present case is of a young girl with facial asymmetry, which had become accentuated during the previous months. A conservative treatment was performed to reduce morbidity and affectation of the lower dental nerve.
December 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27974978/palatal-swelling-a-diagnostic-enigma
#17
Ramalingam Suganya, Narasimhan Malathi, Harikrishnan Thamizhchelvan, Subramaniam Ramkumar, G V V Giri
Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features. It is an expansive and lytic lesion without periosteal reaction and prominent peripheral sclerosis. Giant cells are also seen in other diseases like giant cell granuloma of the jaws, traumatic bone cyst, aneurysmal bone cyst, and jaw tumor of hyperparathyroidism. We present a unique case of GCT of palate in a 30-year-old female...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27957589/radiotherapy-for-aneurysmal-bone-cysts-a%C3%A2-rare-indication
#18
Khaled Elsayad, Jan Kriz, Heinrich Seegenschmiedt, Detlef Imhoff, Reinhard Heyd, Hans Theodor Eich, Oliver Micke
BACKGROUND: Aneurysmal bone cysts (ABC) are rapidly growing benign osseous lesions composed of blood-filled channels separated by fibrous septa. Since the value of external beam radiotherapy (EBRT) for ABC has not been well defined, the German Cooperative Group on Radiotherapy for Benign Diseases performed the national register study described herein. PATIENTS AND METHODS: Five German institutions collected data regarding clinical features, treatment concepts, and outcome for patients with ABC who had been referred for local EBRT over the past 30 years...
December 12, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27933423/how-effective-is-embolization-with-n-2-butyl-cyanoacrylate-for-aneurysmal-bone-cysts
#19
Giuseppe Rossi, Andreas F Mavrogenis, Giancarlo Facchini, Tommaso Bartalena, Eugenio Rimondi, Matteo Renzulli, Andrea Andreone, Stefano Durante, Andrea Angelini, Costantino Errani
PURPOSE: To evaluate the outcome of selective arterial embolization with N-2-butyl-cyanoacrylate for aneurysmal bone cysts. METHODS: We retrospectively studied 102 patients (72 male, 30 female; mean age, 16 years; range, 3-60 years) with aneurysmal bone cysts treated with embolization with N-2-butyl-cyanoacrylate. Mean follow-up was seven years (range, 3-13 years); no patient was lost to follow-up. We evaluated healing and recurrences of the lesions, complications and cost of the procedures, and recurrences with respect to age and gender of the patients, and size and location of the lesions...
December 8, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27918745/simple-and-aneurysmal-bone-cyst-aspects-of-jaw-pseudocysts-based-on-an-experience-of-brazilian-pathology-service-during-53-years
#20
I-L Flores, M-E Hamilton, EdeF Zanchin-Baldissera, A-C Uchoa-Vasconcelos, S-B Chaves-Tarquinio, A-P Neutzling-Gomes
BACKGROUND: Jaw pseudocysts are benign osseous lesions of unclear etiology. Among these, the simple bone cyst (SBC) and aneurysmal bone cyst (ABC) are intriguing bone pathologies still rarely studied together. This retrospective study aimed to present the long-term case series of patients with jaw pseudocysts focusing on the clinical, radiographic, and transoperative aspects. MATERIAL AND METHODS: A retrospective case series of patients with SBC and ABC was performed...
January 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
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