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Aneurysmal bone cyst

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https://www.readbyqxmd.com/read/27918745/simple-and-aneurysmal-bone-cyst-aspects-of-jaw-pseudocysts-based-on-an-experience-of-brazilian-pathology-service-during-53-years
#1
I Flores, M-E Hamilton, E-F Zanchin-Baldissera, A-C Uchoa-Vasconcelos, S-B Chaves-Tarquinio, A-P Neutzling-Gomes
BACKGROUND: Jaw pseudocysts are benign osseous lesions of unclear etiology. Among these, the simple bone cyst (SBC) and aneurysmal bone cyst (ABC) are intriguing bone pathologies still rarely studied together. This retrospective study aimed to present the long-term case series of patients with jaw pseudocysts focusing on the clinical, radiographic, and transoperative aspects. MATERIAL AND METHODS: A retrospective case series of patients with SBC and ABC was performed...
December 6, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27910166/anchored-multiplex-pcr-for-targeted-next-generation-sequencing-reveals-recurrent-and-novel-usp6-fusions-and-upregulation-of-usp6-expression-in-aneurysmal-bone-cyst
#2
Natalya V Guseva, Omar Jaber, Munir R Tanas, Aaron A Stence, Ramakrishna Sompallae, Jenna Schade, Allison N Fillman, Benjamin J Miller, Aaron D Bossler, Deqin Ma
Primary aneurysmal bone cyst (ABC) is a neoplastic process due to recurrent translocations involving the USP6 gene. By fluorescence in situ hybridization, up to 69% of primary ABCs harbored USP6 translocations; no USP6 translocation was found in secondary ABC or giant cell tumor of bone (GCT). GCT can recur locally, metastasize to the lungs in some cases, and rarely undergo malignant transformation. Differentiating primary ABC from its mimics is important for treatment and prognosis. We evaluated USP6 fusion and expression in 13 cases of primary and 1 case of secondary ABC, and 9 cases of GCT using nucleic acid extracted from formalin-fixed, paraffin-embedded tissue and a next generation sequencing (NGS)-based assay...
November 7, 2016: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/27903019/osteochondroma-presenting-as-a-calcified-mass-in-the-sellar-region-and-review-of-the-literature
#3
Kazuya Sekiguchi, Satoshi Tsutsumi, Sho Arai, Senshu Nonaka, Takamoto Suzuki, Hisato Ishii, Hiroshi Izumi, Yukimasa Yasumoto
Objective Osteochondroma (OC) is the most common benign bone neoplasm. It infrequently occurs in the cranial cavity as a calcified lesion and very rarely presents in the sellar region. The present study summarizes the knowledge about OCs of the sellar region. Methods We searched the literature search for the clinical appearance of OCs and other calcified pathologies occurring in the sellar region. Results A total of 21 English-language articles published from 1961 to 2015 documented cases of calcified lesions in the sellar region including cerebral aneurysm, chondroid chordoma, chondroma, craniopharyngioma, OC, odontome, osteoma, pituitary adenoma, pituitary stone, Rathke cleft cyst, retinoblastoma, schwannoma, and xanthogranuloma...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27902174/total-patellectomy-for-patellar-aneurysmal-bone-cyst
#4
Mehmet Çetinkaya, Hamza Özer, Hakan Y Selek, Selim Erekul
Herein we report a case of patellar aneurysmal bone cyst of a 32-year-old female patient who was admitted to our outpatient clinic due to the swelling on her left knee. She was describing no trauma history but increasing pain and that the mass was expanding gradually by the time. Although it occurs rarely in patella, evaluation by radiographic and magnetic resonance images revealed that the mass was due to the patellar aneurysmal bone cyst, which also destructed the surface of the joint. Although there was no impairment in the range of motion of the patient's left knee in the preoperative evaluation, because of the destruction, we performed total patellectomy and extensor mechanism reconstruction by Zaricznyj technique instead of curettage and grafting...
December 2016: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/27853880/frontal-skull-osteoblastoma-with-aneurysmal-bone-cyst-like-changes-associated-with-trauma-during-pregnancy-a-case-report
#5
Sebastian M Toescu, Andrew F Alalade, Louise Steele, Deepti Bhargava, Roger Hunter
We report the case of a large osteoblastoma arising in the frontal bone of a 20-year-old female. The lesion was first noted after a fall, and grew steadily in size following further head injury during pregnancy. Initial plain radiography demonstrated an area of radiolucency, with subsequent cross-sectional imaging revealing the extent of the lesion. Following successful surgical resection, histological features were suggestive of an aggressive osteoblastoma with aneurysmal bone cyst-like changes. We consider the influence of pregnancy and trauma on osteoblastoma behavior...
November 16, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27852643/correlation-between-apparent-diffusion-coefficient-and-histopathology-subtypes-of-osteosarcoma-after-neoadjuvant-chemotherapy
#6
Jifei Wang, Meili Sun, Dawei Liu, Xiaoshu Hu, Margaret H Pui, Quanfei Meng, Zhenhua Gao
BACKGROUND: Neoadjuvant chemotherapy has made limb-salvage surgery possible for the patients with osteosarcoma. Diffusion-weighted magnetic resonance imaging (DWI) has been used to monitor chemotherapy response. PURPOSE: To correlate the apparent diffusion coefficient (ADC) values with histopathology subtypes of osteosarcoma after neoadjuvant chemotherapy. MATERIAL AND METHODS: Twelve patients with osteoblastic (n = 7), chondroblastic (n = 4), and fibroblastic (n = 1) osteosarcomas underwent post-chemotherapy DWI before limb-salvage surgery...
November 16, 2016: Acta Radiologica
https://www.readbyqxmd.com/read/27826699/a-unique-case-of-multiple-non-ossifying-fibromas-with-polyostotic-monomelic-distribution-and-aggressive-clinical-course
#7
Alessandro Corsi, Cristina Remoli, Mara Riminucci, Ernesto Ippolito, John Dimitriou
Multiple non-ossifying fibromas (MNOFs) occur either isolated or in association with other anomalies, are usually localized in the long bones of the lower limbs, may be radiographically confused with other skeletal lesions, and tend to heal spontaneously with the completion of the skeletal growth. Segmental distribution, either monomelic or polymelic and ipsilateral, is rare and commonly observed in the context of developmental diseases known as "RASopathies", which are caused by mutations in genes that encode components or regulators within the Ras/mitogen-activated protein kinase signaling pathway...
November 8, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27778155/current-management-of-aneurysmal-bone-cysts
#8
REVIEW
Howard Y Park, Sara K Yang, William L Sheppard, Vishal Hegde, Stephen D Zoller, Scott D Nelson, Noah Federman, Nicholas M Bernthal
Aneurysmal bone cysts (ABCs) are benign bone lesions arising predominantly in the pediatric population that can cause local pain, swelling, and pathologic fracture. Primary lesions, which constitute roughly two thirds of all ABCs, are thought to be neoplastic in nature, with one third of ABCs arising secondary to other tumors. Diagnosis is made with various imaging modalities, which exhibit characteristic features such as "fluid-fluid levels," although biopsy is critical, as telangiectatic osteosarcoma cannot be excluded based on imaging alone...
December 2016: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/27743037/treatment-of-aneurysmal-bone-cysts-by-percutaneous-ct-guided-injection-of-calcitonin-and-steroid
#9
Connie Y Chang, Susan V Kattapuram, Ambrose J Huang, F Joseph Simeone, Martin Torriani, Miriam A Bredella
OBJECTIVES: To determine the efficacy and safety of percutaneous calcitonin and steroid injection in the treatment of aneurysmal bone cysts (ABCs). MATERIALS AND METHODS: Our study was IRB-approved and HIPAA-compliant. We reviewed pre- and post-procedural imaging studies and medical records of all CT-guided percutaneous injections of ABCs with calcitonin and steroid performed at our institution between 2003 and 2015. RESULTS: Treatment success based on imaging was categorized as substantial (51-100 %), partial (1-50 %), or none (0 %) by comparing radiographs of the lesion before and after treatment...
October 14, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27742510/ruptured-aneurysms-of-the-occipital-artery-associated-with-congenital-occipital-bone-defect-a-case-report
#10
Toshinari Kawasaki, Kazumichi Yoshida, Takayuki Kikuchi, Akira Ishii, Yasushi Takagi, Susumu Miyamoto
BACKGROUND: Concerning traumatic aneurysms, those of the superficial temporal artery (STA) have been frequently reported in the literature, whereas those of the occipital artery (OA) are extremely rare. CASE DESCRIPTION: A 30-year-old man had been followed at another hospital for meningoencephalocele associated with his congenital occipital bone defect. He was admitted to our hospital with a chief complaint of neck swelling and pain during a football game. CT and MRI showed a hematoma in his right neck along with the meningoencephalocele...
October 11, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27737291/malignant-transformation-of-an-aneurysmal-bone-cyst-to-fibroblastic-osteosarcoma
#11
Akash P Kansagra, Jennifer J Wan, Kavi K Devulapalli, Andrew E Horvai, Richard J O'Donnell, Thomas M Link
Aneurysmal bone cysts are uncommon primary bone tumors typically regarded as histologically and clinically benign. Malignant transformation of these lesions occurs almost exclusively in the context of prior radiation exposure. However, 4 cases of an osteosarcoma developing without prior radiation exposure have been reported. In this article, we report a fifth case of degeneration of an aneurysmal bone cyst to a fibroblastic osteosarcoma. In addition to reviewing the earlier cases, we describe the radiologic, pathologic, and immunohistochemical basis of this diagnosis...
September 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27721719/malignant-phyllodes-tumor-including-aneurysmal-bone-cyst-like-areas-in-pregnancy-a-case-report-and-review-of-the-literature
#12
Canan Kelten, Ceren Boyaci, Cem Leblebici, Kemal Behzatoglu, Didem C Trabulus, Serkan Sari, Mehmet A Nazli, Erol R Bozkurt
BACKGROUND: Malignant phyllodes tumors of the breast are rare biphasic neoplasms. Only few cases related to pregnancy have been reported. CASE REPORT: A 37-year-old woman presented with swelling and pain in her left breast as well as hyperemia on the breast skin, 4 weeks after labor. In her family history, her aunt and maternal cousin had had a breast cancer diagnosis. Clinical evaluation of the patient was consistent with a breast abscess. Therefore, abscess drainage and biopsy from the cavity wall were performed...
August 2016: Breast Care
https://www.readbyqxmd.com/read/27718436/management-of-aggressive-giant-cell-tumor-of-calcaneal-bone-a-case-report
#13
Achmad Fauzi Kamal, Agus Waryudi, Zuhri Effendi, Evelina Kodrat
INTRODUCTION: Prevalence of giant cell tumor (GCT) at atypical locations like bones of the feet are rare, seen in <1% of cases. GCT may have aggressive features, including cortical expansion or destruction with a soft-tissue component. Difficult diagnosis most often followed with complicated management and high recurrence rate remains a challenge that is rarely reported. PRESENTATION OF CASE: We presented a case of forty-six-year-old male patient with giant cell tumor of the right calcaneus Campanacci 3 with secondary aneurysmal bone cyst (ABC)...
September 28, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27698855/aneurysmal-bone-cyst-of-the-metatarsal-a-case-report
#14
Jiangyinzi Shang, Runsheng Guo, Ping Zhan, Chuwen Chen, Jing Kan, Hucheng Liu, Min Dai
An aneurysmal bone cyst (ABC) is a rare, non-neoplastic, destructive, hemorrhagic and expansile lesion accounting for 1% of all bone tumors. This type of lesion predominantly affects long bones and vertebrae. ABC of the metatarsal is rare and only a few cases have been reported in the literature to date. The present study reports a rare case of ABC of the third metatarsal occurring in a 27-year-old male patient, who presented with repeated foot swelling that had lasted for ~1 year. Other clinical manifestations included limping, multiple lumps (defined as masses on or below the skin, as detected by imageological diagnosis) and progressively increasing local pain in his right foot...
October 2016: Oncology Letters
https://www.readbyqxmd.com/read/27695554/primary-aneurysmal-bone-cyst-of-the-petrous-temporal-bone-a-case-report-and-review-of-literature
#15
Mayur Sharma, Vernon Velho, Hrushikesh Kharosekar
Aneurysmal bone cyst (ABC) arising in the petrous portion of the temporal bone is a rare entity with only five such reported cases in the literature. We report the case of a 28-year-old man who presented with a tender swelling in the right preauricular region with right ear discharge and conductive hearing loss of 4 years' duration. Computed tomography and Magnetic Resonance imaging showed a destructive lesion in the right petrous bone with cavitation consistent with the diagnosis of ABC. Gross total resection of the lesion was achieved and diagnosis was confirmed histologically...
October 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27649673/denosumab-non-surgical-treatment-option-for-selective-arterial-embolization-resistant-aneurysmal-bone-cyst-of-the-spine-and-sacrum-case-report
#16
R Ghermandi, S Terzi, A Gasbarrini, S Boriani
OBJECTIVE: Aneurysmal Bone Cyst (ABC) is a cystic lesion of bone, occurring in 70% of cases as a primary lesion. Even if the metaphyseal region of long bones is more frequently involved, vertebral localization is not rare: ABC represents 15% of all primary spine and sacral tumours. Selective arterial embolization (SAE) represents the first treatment option for vertebral ABC. However, in few cases, multiple SAEs are not possible. The aim of this work is to report two cases of vertebral ABC unresponsive to SAE positively treated with Denosumab...
September 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27644571/delayed-diagnosis-of-primary-bone-and-soft-tissue-tumors-initially-treated-as-degenerative-spinal-disorders
#17
Toshihiko Nishisho, Toshinori Sakai, Fumitake Tezuka, Kosaku Higashino, Shoichiro Takao, Yoichiro Takata, Ryo Miyagi, Shunichi Toki, Mitsunobu Abe, Kazuta Yamashita, Akihiro Nagamachi, Koichi Sairyo
Background Symptoms of primary bone and soft tissue tumors located in the trunk mimic those of degenerative spinal disorders such as low back pain or pain or numbness of the legs. Due to their rarity, especially in sarcoma located in the trunk, diagnosis is sometimes delayed. Methods A retrospective review was performed of the records of 383 patients with primary bone and soft tissue tumors who visit our out patient clinic from 2011 to 2013 at a single institution. Patients with delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders for more than 2 months were identified...
2016: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/27614921/en-bloc-excision-and-matched-metatarsal-transfer-for-expansive-benign-osteolytic-lesions-of-the-metacarpal
#18
Samuel C R Pallapati, Binu Prathap Thomas, George A Anderson
PURPOSE: Benign aggressive expansile osteolytic lesions such as giant cell tumors and aneurysmal bone cysts involving the metacarpal head pose problems in management. Unacceptably high rates of recurrence are reported after curettage and bone grafting. An en bloc excision of such tumors ideally requires osteoarticular replacement of the excised metacarpal heads to retain mobility and function. We used nonvascularized metatarsal head and shaft harvested from the foot to replace the metacarpal defect after en bloc resection to retain movement and function of metacarpophalangeal (MCP) joint...
September 7, 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27526293/histologic-spectrum-of-giant-cell-tumor-gct-of-bone-in-patients-18-years-of-age-and-below-a-study-of-63-patients
#19
Alyaa Al-Ibraheemi, Carrie Y Inwards, Riyam T Zreik, Doris E Wenger, Sarah M Jenkins, Jodi M Carter, Jennifer M Boland, Peter S Rose, Long Jin, Andre M Oliveira, Karen J Fritchie
Although the majority of giant cell tumors (GCTs) of the bone occur in adult patients, occasionally they arise in the pediatric population. In this setting they may be mistaken for tumors more commonly seen in this age group, including osteosarcoma, aneurysmal bone cyst, and chondroblastoma. All cases of primary GCT of the bone arising in patients 18 years and below were retrieved from our institutional archives and examined with emphasis on the evaluation of various morphologic patterns. Clinical/radiologic records were reviewed when available...
August 11, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27517069/evaluation-of-clinical-results-and-complications-of-structural-allograft-reconstruction-after-bone-tumor-surgery
#20
Mohammad Gharedaghi, Mohammad Taghi Peivandi, Mehdi Mazloomi, Hasan Rahimi Shoorin, Mohammad Hasani, Parham Seyf, Fatemeh Khazaee
BACKGROUND: Massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. The purpose of this study was to analyze the outcome of these procedures at Imam Reza Hospital, Mashhad University of Medical Sciences. METHODS: In this study, 113 cases have been presented. Eleven cases were excluded (patients has a traumatic defect or they passed away before the completion of the study's two-year follow up period)...
June 2016: Archives of Bone and Joint Surgery
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