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Ultrafine particles

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https://www.readbyqxmd.com/read/28211537/ambient-ultrafine-particle-ingestion-alters-gut-microbiota-in-association-with-increased-atherogenic-lipid-metabolites
#1
Rongsong Li, Jieping Yang, Arian Saffari, Jonathan Jacobs, Kyung In Baek, Greg Hough, Muriel H Larauche, Jianguo Ma, Nelson Jen, Nabila Moussaoui, Bill Zhou, Hanul Kang, Srinivasa Reddy, Susanne M Henning, Matthew J Campen, Joseph Pisegna, Zhaoping Li, Alan M Fogelman, Constantinos Sioutas, Mohamad Navab, Tzung K Hsiai
Ambient particulate matter (PM) exposure is associated with atherosclerosis and inflammatory bowel disease. Ultrafine particles (UFP, dp < 0.1-0.2 μm) are redox active components of PM. We hypothesized that orally ingested UFP promoted atherogenic lipid metabolites in both the intestine and plasma via altered gut microbiota composition. Low density lipoprotein receptor-null (Ldlr(-/-)) mice on a high-fat diet were orally administered with vehicle control or UFP (40 μg/mouse/day) for 3 days a week...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28188054/exposure-to-air-pollutants-during-commuting-in-london-are-there-inequalities-among-different-socio-economic-groups
#2
Ioar Rivas, Prashant Kumar, Alex Hagen-Zanker
People with low income often experience higher exposures to air pollutants. We compared the exposure to particulate matter (PM1, PM2.5 and PM10), Black Carbon (BC) and ultrafine particles (PNCs; 0.02-1μm) for typical commutes by car, bus and underground from 4 London areas with different levels of income deprivation (G1 to G4, from most to least deprived). The highest BC and PM concentrations were found in G1 while the highest PNC in G3. Lowest concentrations for all pollutants were observed in G2. We found no systematic relationship between income deprivation and pollutant concentrations, suggesting that differences between transport modes are a stronger influence...
February 7, 2017: Environment International
https://www.readbyqxmd.com/read/28179003/respiratory-outcomes-of-ultrafine-particulate-matter-ufpm-as-a-surrogate-measure-of-near-roadway-exposures-among-bicyclists
#3
Hye-Youn Park, Susan Gilbreath, Edward Barakatt
BACKGROUND: Studies have shown a consistent association between exposure to traffic-related air pollution and adverse health effects. In particular, exposure can be high for cyclists who travel near roadways. The objective of the current study was to examine the relationship between short-term exposure of near-road traffic emissions and acute changes in lung function among individuals who frequently bike in the Sacramento and Davis areas in California. Ultrafine particulate matter (UFPM) was used as a surrogate for near-roadway exposure in this study since the main source of this pollutant is from motor vehicle exhaust...
February 8, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28167447/associations-between-ambient-wood-smoke-and-other-particulate-pollutants-and-biomarkers-of-systemic-inflammation-coagulation-and-thrombosis-in-cardiac-patients
#4
Daniel P Croft, Scott J Cameron, Craig N Morrell, Charles J Lowenstein, Frederick Ling, Wojciech Zareba, Philip K Hopke, Mark J Utell, Sally W Thurston, Kelly Thevenet-Morrison, Kristin A Evans, David Chalupa, David Q Rich
BACKGROUND: Increased particulate air pollution has been associated with both an increased risk of myocardial infarction (MI) and adverse changes in cardiac biomarkers. Up to 30% of ambient wintertime fine particles (PM2.5) in Rochester, NY are from wood burning. Our study examined associations between ambient levels of a marker of wood smoke (Delta-C) and other particulate air pollutants and biomarkers of inflammation, coagulation and thrombosis. METHODS: We measured blood concentrations of C-reactive protein (CRP), D-dimer, fibrinogen, P-selectin, platelet factor 4 (PF-4), von Willebrand factor (vWF), and myeloperoxidase (MPO) of 135 patients undergoing cardiac catheterization during the winters of 2011-2013...
February 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28165927/is-3d-printing-safe-analysis-of-the-thermal-treatment-of-thermoplastics-abs-pla-pet-and-nylon
#5
Szymon Wojtyła, Piotr Klama, Tomasz Baran
The fast development of low-cost desktop three-dimensional (3D) printers has made those devices widely accessible for goods manufacturing at home. However, is it safe? Users may belittle the effects or influences of pollutants (organic compounds and ultrafine particles) generated by the devices in question. Within the scope of this study, the authors attempt to investigate thermal decomposition of the following commonly used, commercially available thermoplastic filaments: acrylonitrile-butadiene-styrene (ABS), polylactic acid (PLA), polyethylene terephthalate (PET), and nylon...
February 6, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28165418/participatory-democracy-community-organizing-and-the-community-assessment-of-freeway-exposure-and-health-cafeh-partnership
#6
Linda Sprague Martinez, Ellin Reisner, Maria Campbell, Doug Brugge
Background: Conflicting interests, power imbalance and relationships characterized by distrust are just a few of the many challenges community-academic research partnerships face. In addition, the time it takes to build relationships is often overlooked, which further complicates matters and can leave well-intentioned individuals re-creating oppressive conditions through inauthentic partnerships. This paper presents a novel approach of using meeting minutes to explore partnership dynamics. The Community Assessment of Freeway Exposure and Health (CAFEH) partnership is used as an illustrative case study to identify how community academic partnerships overcome the challenges associated with community-based participatory research (CBPR)...
February 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28163602/differential-pattern-of-deposition-of-nanoparticles-in-the-airways-of-exposed-workers
#7
Elizabeth Fireman, Rinat Edelheit, Moshe Stark, Amir Bar Shai
Ultrafine particles (UFP) have been postulated to significantly contribute to the adverse health effects associated with exposure to particulate matter (PM). Due to their extremely small size (aerodynamic diameter <100 nm), UFP are able to deposit deep within the lung after inhalation and evade many mechanisms responsible for the clearance of larger particles. There is a lack of biologically relevant personal exposure metrics for exposure to occupational- and environmental-related micro- and nano-sized PM...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28160538/fine-and-ultrafine-aerosol-in-ostrava-ambient-air
#8
Karel Lach, Karel Klouda, Vladimír Mička, Lucie Hellebrandová
Air quality in the Moravian-Silesian Region and especially in the Ostrava agglomeration represents a very important factor influencing the environment and health of the local population. The area has been burdend for more than two centuries with rapid development of the mining industry and related metallurgical and chemical production. As a result, hundreds of tons of pollutants have progressively been released into the atmosphere. Some of them have been gradually eliminated from the environment; others, such as some heavy metals, remain locally present and burden the local landscape...
December 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28153538/photo-pollution-stress-in-skin-traces-of-pollutants-pah-and-particulate-matter-impair-redox-homeostasis-in-keratinocytes-exposed-to-uva1
#9
Jérémie Soeur, Jean-Philippe Belaïdi, Christel Chollet, Laurence Denat, Ariane Dimitrov, Christophe Jones, Philippe Perez, Martine Zanini, Olivia Zobiri, Sakina Mezzache, Dominique Erdmann, Guillaume Lereaux, Joan Eilstein, Laurent Marrot
BACKGROUND: It is likely that skin is exposed to low concentrations of pollutants such as Polycyclic Aromatic Hydrocarbons (PAH) either through topical penetration by ultrafine particles or by systemic distribution. No precise estimation of pollutants in living skin is available, but literature has reported contamination of blood by PAH at concentrations in the nanomolar range. Some pollutants (PAH for example) are photo-reactive and phototoxic: sunlight and pollution might thus synergistically compromise skin health...
January 16, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28148272/dose-dependent-induction-of-astrocyte-activation-and-reactive-astrogliosis-in-mouse-brain-following-maternal-exposure-to-carbon-black-nanoparticle
#10
Atsuto Onoda, Ken Takeda, Masakazu Umezawa
BACKGROUND: Recent studies indicate that maternal exposure to ambient ultrafine particles and nanoparticles has adverse effects of on the central nervous system. Quantitative dose-response data is required to better understand the developmental neurotoxicity of nanoparticles. The present study investigated dose-dependent effects of maternal exposure to carbon black nanoparticle (CB-NP) on astrocyte in the brains of mouse offspring. METHODS: A CB-NP suspension (2...
2, 2017: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/28146409/granularity-and-laxative-effect-of-ultrafine-powder-of-dendrobium-officinale
#11
DanDan Luo, Chao Qu, ZhenBiao Zhang, JianHui Xie, LieQiang Xu, HongMei Yang, CaiLan Li, GuoSheng Lin, HongFeng Wang, ZiRen Su
Constipation is a common disorder that is a significant source of morbidity among people around the world ranging from 2% to 28%. Dendrobium officinale Kimura et Migo is a traditional herbal medicine and health food used for tonicity of the stomach and promotion of body fluid production in China. This study aimed to prepare the ultrafine powder of Dendrobium officinale (UDO) and investigate its laxative effect and potential mechanism in mice with diphenoxylate-induced constipation. Results indicated that the mean diameter (d50) of UDO obtained by ball milling was 6...
February 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28146089/electrosurgical-smoke-ultrafine-particle-measurements-and-work-environment-quality-in-different-operating-theatres
#12
Francesco Romano, Jan Gustén, Stefano De Antonellis, Cesare M Joppolo
Air cleanliness in operating theatres (OTs) is an important factor for preserving the health of both the patient and the medical staff. Particle contamination in OTs depends mainly on the surgery process, ventilation principle, personnel clothing systems and working routines. In many open surgical operations, electrosurgical tools (ESTs) are used for tissue cauterization. ESTs generate a significant airborne contamination, as surgical smoke. Surgical smoke is a work environment quality problem. Ordinary surgical masks and OT ventilation systems are inadequate to control this problem...
January 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28140833/nanoparticles-induced-apoptosis-of-human-airway-epithelium-is-mediated-by-prongf-p75-ntr-signaling
#13
Sreeparna Chakraborty, Vincent Castranova, Miriam K Perez, Giovanni Piedimonte
Environmental and occupational exposures to respirable ultrafine fractions of particulate matter (PM) have been implicated in the initiation and exacerbation of lung diseases. However, the precise mechanisms underlying production of cell damage and death attributed to nanoparticles (NP) on human airway epithelium are not fully understood. This study examined the role of neurotrophic pathways in NP-induced airway toxicity. Size and agglomeration of TiO2 nanoparticles (TiO2-NP) and fine (TiO2-FP) particles were measured by dynamic light scattering...
2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28134841/ultrafine-and-fine-particulate-matter-inside-and-outside-of-mechanically-ventilated-buildings
#14
Shelly L Miller, Nick A Facciola, Darin Toohey, John Zhai
The objectives of this study were to measure levels of particulate matter (PM) in mechanically ventilated buildings and to improve understanding of filtration requirements to reduce exposure. With the use of an Ultra High Sensitivity Aerosol Spectrometer and an Aerodyne Mass Spectrometer, ultrafine (0.055-0.1 μm) and fine (0.1-0.7 μm) indoor and outdoor PM was measured as a function of time in an office, a university building, and two elementary schools. Indoor particle levels were highly correlated with outdoor levels...
January 28, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28125025/inhaled-pollutants-the-molecular-scene-behind-respiratory-and-systemic-diseases-associated-with-ultrafine-particulate-matter
#15
REVIEW
Hussein Traboulsi, Necola Guerrina, Matthew Iu, Dusica Maysinger, Parisa Ariya, Carolyn J Baglole
Air pollution of anthropogenic origin is largely from the combustion of biomass (e.g., wood), fossil fuels (e.g., cars and trucks), incinerators, landfills, agricultural activities and tobacco smoke. Air pollution is a complex mixture that varies in space and time, and contains hundreds of compounds including volatile organic compounds (e.g., benzene), metals, sulphur and nitrogen oxides, ozone and particulate matter (PM). PM0.1 (ultrafine particles (UFP)), those particles with a diameter less than 100 nm (includes nanoparticles (NP)) are considered especially dangerous to human health and may contribute significantly to the development of numerous respiratory and cardiovascular diseases such as chronic obstructive pulmonary disease (COPD) and atherosclerosis...
January 24, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28117141/influence-of-exposure-to-coarse-fine-and-ultrafine-urban-particulate-matter-and-their-biological-constituents-on-neural-biomarkers-in-a-randomized-controlled-crossover-study
#16
Ling Liu, Bruce Urch, Mieczyslaw Szyszkowicz, Mary Speck, Karen Leingartner, Robin Shutt, Guillaume Pelletier, Diane R Gold, James A Scott, Jeffrey R Brook, Peter S Thorne, Frances S Silverman
BACKGROUND: Epidemiological studies have reported associations between air pollution and neuro-psychological conditions. Biological mechanisms behind these findings are still not clear. OBJECTIVES: We examined changes in blood and urinary neural biomarkers following exposure to concentrated ambient coarse, fine and ultrafine particles. METHODS: Fifty healthy non-smoking volunteers, mean age 28years, were exposed to coarse (2.5-10μm, mean 213μg/m(3)) and fine (0...
January 20, 2017: Environment International
https://www.readbyqxmd.com/read/28115126/determination-of-time-and-size-dependent-fine-particle-emission-with-varied-oil-heating-in-an-experimental-kitchen
#17
Shuangde Li, Jiajia Gao, Yiqing He, Liuxu Cao, Ang Li, Shengpeng Mo, Yunfa Chen, Yaqun Cao
Particulate matter (PM) from cooking has caused seriously indoor air pollutant and aroused risk to human health. It is urged to get deep knowledge of their spatial-temporal distribution of source emission characteristics, especially ultrafine particles (UFP<100nm) and accumulation mode particles (AMP 100-665nm). Four commercial cooking oils are auto dipped water to simulate cooking fume under heating to 265°C to investigate PM emission and decay features between 0.03 and 10μm size dimension by electrical low pressure impactor (ELPI) without ventilation...
January 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28111595/physical-properties-and-lung-deposition-of-particles-emitted-from-five-major-indoor-sources
#18
Tuan V Vu, Jakub Ondracek, Vladimir Zdímal, Jaroslav Schwarz, Juana Maria Delgado-Saborit, Roy M Harrison
The physical properties of indoor particles were measured with an Scanning Mobility Particle Sizer (SMPS) system (14.6-850 nm), an Aerodynamic Particle Sizer (APS, 0.54-18 μm) and an Hygroscopic Tandem Differential Mobility Analyzer (H-TDMA) in an apartment located in an urban background site in Prague (Czech Republic) from 15 August to 8 September, 2014. The total particle maximum number concentration was 9.38 × 10(4), 1.46 × 10(5), 2.89 × 10(4), 2.25 × 10(5) and 1.57 × 10(6) particles cm(-3) for particles released from vacuum cleaning, soap/W5 cleaning spray, smoking, incense burning and cooking (frying) activities, respectively...
2017: Air Quality, Atmosphere, & Health
https://www.readbyqxmd.com/read/28111281/aerosolizable-gold-nano-in-micro-dry-powder-formulations-for-theragnosis-and-lung-delivery
#19
A Sofia Silva, Ana M Sousa, Renato P Cabral, Marta C Silva, Clarinda Costa, Sónia P Miguel, Vasco D B Bonifácio, Teresa Casimiro, Ilídio J Correia, Ana Aguiar-Ricardo
Functionalized gold nanoparticles (AuNPs) have been widely investigated as promising multifunctional nanosystems for the theragnosis of lung cancer, the most common and prominent cause of cancer death worldwide. Nevertheless, nanoparticles are not in appropriate sizes for an accurate deep lung delivery and the lack of locally and effective delivery of therapeutic biomolecules to the deep lungs is, in fact, the major cause of low therapeutic outcome. Herein we incorporate, for the first time, AuNPs into respirable microparticles...
January 19, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28110452/comparison-of-trace-elements-in-size-fractionated-particles-in-two-communities-with-contrasting-socioeconomic-status-in-houston-tx
#20
Inkyu Han, Yuncan Guo, Masoud Afshar, Thomas H Stock, Elaine Symanski
Levels of ambient air pollutants, including particulate matter (PM), are often higher in low-socioeconomic status (SES) communities than in high-SES communities. Houston is the fourth largest city in the USA and is home to a large petrochemical industry, an active port, and congested roadways, which represent significant emission sources of air pollution in the region. To compare levels of air pollution between a low-SES and a high-SES community, we simultaneously collected a 7-day integrated size-fractionated PM between June 2013 and November 2013...
February 2017: Environmental Monitoring and Assessment
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