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https://www.readbyqxmd.com/read/29144513/predictors-of-heart-rhythm-disturbances-in-hypertensive-obese-patients-with-obstructive-sleep-apnea
#1
Lyudmila Sergeevna Korostovtseva, Nadezhda Edvinovna Zvartau, Oxana Petrovna Rotar, Yurii Vladimirovich Sviryaev, Aleksandra Olegovna Konradi
Objective: To assess the incidence and predictors of heart rhythm and conduction disturbances in hypertensive obese patients with and without obstructive sleep apnea (OSA). Methods: This is an open, cohort, prospective study. Out of 493 screened patients, we selected 279 hypertensive, obese individuals without severe concomitant diseases: 75 patients without sleep-disordered breathing (non-SDB group), and 204 patients with OSA (OSA group). At baseline, all patients underwent examination, including ECG, Holter ECG monitoring, and sleep study...
September 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29144103/effects-of-home-based-superimposed-neuromuscular-electrical-stimulation-in-severe-chronic-obstructive-pulmonary-disease-patients-a-randomized-controlled-clinical-trial
#2
Marie C Valenza, Irene Torres-Sánchez, Laura López-López, Irene Cabrera-Martos, Araceli Ortiz-Rubio, Gerald Valenza-Demet
BACKGROUND: COPD patients experience a sustained deterioration of several capacities. Those with severe COPD undergo a considerable decline in their physical and functional capacities, but pulmonary rehabilitation (PR) is used to reduce the weakness of such patients. To date, neuromuscular electrical stimulation (NMES) has been used in acute COPD patients but NMES superimposed onto voluntary muscular contraction has not been tested in COPD patients. AIM: The aim of this study was to evaluate the effects of superimposed NMES on the cardiorespiratory performance and functionality of severe COPD patients undergoing a home-based rehabilitation program...
November 16, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29142787/sleep-apnea-symptoms-and-cardiovascular-disease-risks-among-haitian-medical-students
#3
Diana M Rosenthal, Donaldson F Conserve, Dodley Severe, Michaele A Gedeon, Ferdinand Zizi, Georges Casimir, Samy I McFarlane, Girardin Jean Louis
Sleep apnea is a prevalent sleep disorder that disproportionately affects blacks and has been previously studied among Caribbean-born blacks in Brooklyn, New York, but there has been negligible research in the Caribbean, specifically Haiti, and developing countries on this pressing health issue. A total of 373 medical students (mean age=20.6 years ± 2.3 years) from a medical school in Haiti participated in this study. Participants were administered a questionnaire assessing their sleep health and cardiovascular outcomes...
April 2017: Journal of Sleep Disorders & Therapy
https://www.readbyqxmd.com/read/29142479/medication-beliefs-predict-medication-adherence-in-ambulatory-patients-with-decompensated-cirrhosis
#4
Kelly L Hayward, Patricia C Valery, Jennifer H Martin, Antara Karmakar, Preya J Patel, Leigh U Horsfall, Caroline J Tallis, Katherine A Stuart, Penny L Wright, David D Smith, Katharine M Irvine, Elizabeth E Powell, W Neil Cottrell
AIM: To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated cirrhosis. METHODS: One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence (Morisky Medication Adherence Scale), beliefs surrounding medications (Beliefs about Medicines Questionnaire), perceptions of illness and medicines (Brief Illness Perception Questionnaire), and quality of life (Chronic Liver Disease Questionnaire) were examined...
October 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29136483/fitness-sleep-disordered-breathing-symptoms-of-depression-and-cognition-in-inactive-overweight-children-mediation-models
#5
Monika M K Stojek, Amanda K Montoya, Christopher F Drescher, Andrew Newberry, Zain Sultan, Celestine F Williams, Norman K Pollock, Catherine L Davis
OBJECTIVES: We used mediation models to examine the mechanisms underlying the relationships among physical fitness, sleep-disordered breathing (SDB), symptoms of depression, and cognitive functioning. METHODS: We conducted a cross-sectional secondary analysis of the cohorts involved in the 2003-2006 project PLAY (a trial of the effects of aerobic exercise on health and cognition) and the 2008-2011 SMART study (a trial of the effects of exercise on cognition). A total of 397 inactive overweight children aged 7-11 received a fitness test, standardized cognitive test (Cognitive Assessment System, yielding Planning, Attention, Simultaneous, Successive, and Full Scale scores), and depression questionnaire...
November 2017: Public Health Reports
https://www.readbyqxmd.com/read/29135910/sleep-disordered-breathing-in-children-with-recurrent-wheeze-asthma-a-single-centre-study
#6
Marco Zaffanello, Emma Gasperi, Laura Tenero, Michele Piazza, Angelo Pietrobelli, Luca Sacchetto, Franco Antoniazzi, Giorgio Piacentini
The relationship between asthma and sleep-disordered breathing is bidirectional due to common risk factors that promote airway inflammation. Obstructive sleep-disordered breathing and recurrent wheeze/asthma are conditions that involve the upper and the lower respiratory system, respectively. The aim of the present study was to investigate the sleep disordered breathing in children with recurrent wheeze/asthma. This was a retrospective study concerning children older than 2 years who underwent-between January 2014 and November 2016-an in-laboratory overnight polygraphic study...
November 14, 2017: Children
https://www.readbyqxmd.com/read/29135535/blood-glucose-concentrations-in-prehospital-trauma-patients-with-traumatic-shock-a-retrospective-analysis
#7
Janett Kreutziger, Wolfgang Lederer, Stefan Schmid, Hanno Ulmer, Volker Wenzel, Maarten W Nijsten, Daniel Werner, Thomas Schlechtriemen
BACKGROUND: Deranged glucose metabolism after moderate to severe trauma with either high or low concentrations of blood glucose is associated with poorer outcome. Data on prehospital blood glucose concentrations and trauma are scarce. OBJECTIVES: The primary aim was to describe the relationship between traumatic shock and prehospital blood glucose concentrations. The secondary aim was to determine the additional predictive value of prehospital blood glucose concentration for traumatic shock when compared with vital parameters alone...
November 11, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29133136/comparison-of-the-near-field-far-field-model-and-the-advanced-reach-tool-art-model-v1-5-exposure-estimates-to-benzene-during-parts-washing-with-mineral-spirits
#8
Mallory LeBlanc, Joseph G Allen, Robert F Herrick, James H Stewart
The Advanced Reach Tool V1.5 (ART) is a mathematical model for occupational exposures conceptually based on, but implemented differently than, the "classic" Near Field/Far Field (NF/FF) exposure model. The NF/FF model conceptualizes two distinct exposure "zones"; the near field, within approximately 1m of the breathing zone, and the far field, consisting of the rest of the room in which the exposure occurs. ART has been reported to provide "realistic and reasonable worst case" estimates of the exposure distribution...
October 31, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29131420/chromatographic-analysis-of-voc-patterns-in-exhaled-breath-from-smokers-and-nonsmokers
#9
Simonetta Capone, Maria Tufariello, Angiola Forleo, Valentina Longo, Lucia Giampietruzzi, Antonio Vincenzo Radogna, Flavio Casino, Pietro Siciliano
Cigarette smoking harms nearly every organ of the body and causes many diseases. The analysis of exhaled breath for exogenous and endogenous Volatile Organic Compounds (VOCs) can provide fundamental information on active smoking and insight into the health damage that smoke is creating. Various exhaled Volatile Organic Compounds (VOCs) have been reported as typical of smoking habit and recent tobacco consumption, but to date, no eligible biomarkers have been identified. Aiming to identify such potential biomarkers, in this pilot study we analysed the chemical patterns of exhaled breath from 26 volunteers divided in groups of nonsmokers and subgroups of smokers sampled at different periods of withdrawal from smoking...
November 13, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29128525/respiratory-rehabilitation-in-multiple-sclerosis-a-narrative-review-of-rehabilitation-techniques
#10
REVIEW
J Levy, H Prigent, D Bensmail
BACKGROUND: Respiratory disorders in multiple sclerosis (MS) are an important issue. They can occur early during the course of the disease, are associated with the neurological impairment, and can lead to pneumonia and respiratory failure, which are the main causes of death in advanced MS. Prevailing impaired expiratory muscles and cough abilities has been demonstrated in this population and might constitute a specific target for rehabilitation interventions. However, international guidelines lack recommendations regarding respiratory rehabilitation in MS...
November 8, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29126085/fatty-acid-binding-protein-genes-of-the-ancient-air-breathing-ray-finned-fish-spotted-gar-lepisosteus-oculatus
#11
Ananda B Venkatachalam, Quenton Fontenot, Allyse Farrara, Jonathan M Wright
With the advent of high-throughput DNA sequencing technology, the genomic sequence of many disparate species has led to the relatively new discipline of genomics, the study of genome structure, function and evolution. Much work has been focused on the role of whole genome duplications (WGD) in the architecture of extant vertebrate genomes, particularly those of teleost fishes which underwent a WGD early in the teleost radiation >230 million years ago (mya). Our past work has focused on the fate of duplicated copies of a multigene family coding for the intracellular lipid-binding protein (iLBP) genes in the teleost fishes...
October 13, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/29124998/evaluation-of-the-presence-of-asbestos-in-cosmetic-talcum-products
#12
Jennifer S Pierce, Alexander S Riordan, Eric W Miller, Shannon H Gaffney, Dana M Hollins
Talc has been used for over a century in a variety of cosmetic products. While pure cosmetic talc (free of asbestos) is not considered a risk factor for mesothelioma, it has been recently suggested that inhalation of cosmetic talc containing trace levels of asbestos is a risk factor for mesothelioma. Bulk analyses of cosmetic talcum products were performed in the 1960s and 1970s, however, the analytical methods used at that time were incapable of determining whether asbestos minerals were present in the asbestiform versus non-asbestiform habit...
August 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29123562/the-role-of-occupational-and-physiotherapy-in-multi-modal-approach-to-tackling-delirium-in-the-intensive-care
#13
REVIEW
Jenny Rains, Nigel Chee
The presence of delirium within critical care remains a long-standing challenge for patients and clinicians alike. A myriad of pre-disposing and precipitating factors lead to this patient cohort being high risk for developing delirium during their critical care stay. Until now, non-pharmacological management of these patients usually encompasses a 'bundle' of principles to reduce delirium days. These bundles have limited focus on the entire multi-disciplinary team (including occupational therapists and physiotherapists) who could assist with the reduction of delirium...
November 2017: J Intensive Care Soc
https://www.readbyqxmd.com/read/29123390/hyperinflated-lungs-compress-the-heart-during-expiration-in-copd-patients-a-new-finding-on-dynamic-ventilation-computed-tomography
#14
Yanyan Xu, Tsuneo Yamashiro, Hiroshi Moriya, Maho Tsubakimoto, Nanae Tsuchiya, Yukihiro Nagatani, Shin Matsuoka, Sadayuki Murayama
Purpose: The aims of this study were to evaluate dynamic changes in heart size during the respiratory cycle using four-dimensional computed tomography (CT) and to understand the relationship of these changes to airflow limitation in smokers. Materials and methods: A total of 31 smokers, including 13 with COPD, underwent four-dimensional dynamic-ventilation CT during regular breathing. CT data were continuously reconstructed every 0.5 s, including maximum cross-sectional area (CSA) of the heart and mean lung density (MLD)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29123150/lung-clearance-index-and-quantitative-computed-tomography-of-post-infectious-bronchiolitis-obliterans-in-infants
#15
Yoon Hee Kim, Hyun Joo Shin, In Suk Sol, Soo Yeon Kim, Jong Deok Kim, Haesung Yoon, Kyung Won Kim, Myung-Joon Kim, Mi-Jung Lee, Myung Hyun Sohn
Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest computed tomography (CT); however, these tests are limited in infants. We aimed to evaluate the utility of lung clearance index (LCI) and air-trapping lung volume from chest CT in infants. This prospective study included 20 infants (mean age, 10.9 ± 6.3 months) diagnosed with post-infectious BO between 2009 and 2016. All subjects underwent multiple breath washout tests. For quantitative analysis of chest CT, the mean lung area attenuation value was used as an individual cutoff to determine the air-trapping lung volume...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29122314/blood-transcriptional-and-microrna-responses-to-short-term-exposure-to-disinfection-by-products-in-a-swimming-pool
#16
Almudena Espín-Pérez, Laia Font-Ribera, Karin van Veldhoven, Julian Krauskopf, Lutzen Portengen, Marc Chadeau-Hyam, Roel Vermeulen, Joan O Grimalt, Cristina M Villanueva, Paolo Vineis, Manolis Kogevinas, Jos C Kleinjans, Theo M de Kok
BACKGROUND: Swimming in a chlorinated pool results in high exposure levels to disinfection by-products (DBPs), which have been associated with an increased risk of bladder cancer. OBJECTIVES: By studying molecular responses at the blood transcriptome level we examined the biological processes associated with exposure to these compounds. METHODS: Whole-genome gene expression and microRNA analysis was performed on blood samples collected from 43 volunteers before and 2h after 40min swimming in an indoor chlorinated pool (PISCINAII study)...
January 2018: Environment International
https://www.readbyqxmd.com/read/29120608/biochemical-gas-sensors-biosniffers-using-forward-and-reverse-reactions-of-secondary-alcohol-dehydrogenase-for-breath-isopropanol-and-acetone-as-potential-volatile-biomarkers-of-diabetes-mellitus
#17
Po-Jen Chien, Takuma Suzuki, Masato Tsujii, Ming Ye, Isao Minami, Kanako Toda, Hiromi Otsuka, Koji Toma, Takahiro Arakawa, Kouji Araki, Yasuhiko Iwasaki, Kayoko Shinada, Yoshihiro Ogawa, Kohji Mitsubayashi
This study describes two biosniffers to determine breath acetone and isopropanol (IPA) levels and applies them for breath measurement in healthy subjects and diabetic patients. Secondary alcohol dehydrogenase (S-ADH) can reduce acetone and oxidize nicotinamide adenine dinucleotide (NADH to NAD(+)) in a weak acid environment. NADH can be excited by 340 nm excitation lights and subsequently emit 490 nm fluorescence. Therefore, acetone can be measured by the decrease in NADH fluorescence intensity. S-ADH can also oxidize IPA and reduce NAD(+) to NADH when it is in an alkaline environment...
November 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29119724/evaluation-of-first-line-bismuth-containing-7-day-concomitant-quintuple-therapy-for-helicobacter-pylori-eradication
#18
Jianfang Ye, Junbo Hong, Yin Zhu, Yong Xie, Xu Shu, Lingyu Luo, Chuan Xie, Zhenhua Zhu, Nonghua Lu
BACKGROUND: Helicobacter pylori infection is difficult to cure, mainly due to antibiotic resistance. We performed a trial to determine the efficacy and safety of a bismuth-containing 7-day concomitant quintuple regimen for the eradication of H. pylori. METHODS: Conducted from August 2015 to February 2016 at First Affiliated Hospital of Nanchang University, this prospective trial enrolled 70 untreated H. pylori-positive patients. Patients received 7-day quintuple therapy consisting of bismuth subcitrate 220 mg, esomeprazole 20 mg, clarithromycin 500 mg, amoxicillin 1 g, and metronidazole 400 mg, each twice daily...
November 9, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29119158/resonance-raman-and-ir-spectroscopy-of-aligned-carbon-nanotube-arrays-with-extremely-narrow-diameters-prepared-with-molecular-catalysts-on-steel-substrates
#19
Sagar Motilal Jain, Federico Cesano, Domenica Scarano, Tomas Edvinsson
Carbon nanotubes (CNTs) are considered promising for a large range of emerging technologies ranging from advanced electronics to utilization as nanoreactors. Here we report a controlled facile synthesis of aligned carbon nanotubes with very small dimensions directly grown on steel grid substrates via two-step catalytic chemical vapor deposition (CCVD) of a molecular catalyst (ferrocene) with ethylene as the carbon source. The system is characterized by resonance Raman spectroscopy and the results show single walled carbon nanotube (SWCNT) arrays composed of 0...
November 9, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29117882/excessive-daytime-sleepiness-in-acute-ischemic-stroke-association-with-restless-legs-syndrome-diabetes-mellitus-obesity-and-sleep-disordered-breathing
#20
Pavel Šiarnik, Katarína Klobučníková, Pavol Šurda, Matúš Putala, Stanislav Šutovský, Branislav Kollár, Peter Turčáni
STUDY OBJECTIVES: Sleep disorders are frequent in stroke patients. The prevalence of sleep-disordered breathing (SDB), excessive daytime sleepiness (EDS), and restless legs syndrome (RLS) among stroke survivors is up to 91%, 72%, and 15%, respectively. Although the relationship between EDS and SDB is well described, there are insufficient data regarding the association of EDS with RLS. The aim of this study was to explore the association between EDS, SDB, and RLS in acute ischemic stroke...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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