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https://www.readbyqxmd.com/read/29140751/further-delineation-of-the-oculoauricular-syndrome-phenotype-a-new-family-with-a-novel-truncating-hmx1-mutation
#1
Ghada M H Abdel-Salam, Mohamed S Abdel-Hamid, Mennat I Mehrez, Ahmad M Kamal, Mohamed B Taher, Hanan H Afifi
Biallelic HMX1 mutations cause a very rare autosomal recessive genetic disorder termed as oculoauricular syndrome (OAS) because it is characterized only by the combination of eye and ear anomalies. We identified a new family bringing to three the total families reported with this disorder. Our proband presented with anteriorly protruded ears and malformed ear pinnae in association with microphthalmia, congenital cataract, microcornea, and iris and optic disc colobomata. Additionally, he had high and broad forehead with asymmetry giving a recognizable facial gestalt...
November 15, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29117900/gestalt-for-shock-and-mortality-in-the-emergency-department-a-prospective-study
#2
Yan-Ling Li, Jun-Rong Mo, Nga-Man Cheng, Stewart S W Chan, Pei-Yi Lin, Xiao-Hui Chen, Colin A Graham, Timothy H Rainer
OBJECTIVE: The diagnosis of shock in patients presenting to the emergency department (ED) is often challenging. We aimed to compare the accuracy of experienced emergency physician gestalt against Li's pragmatic shock (LiPS) tool for predicting the likelihood of shock in the emergency department, using 30-day mortality as an objective standard. METHOD: In a prospective observational study conducted in an urban, academic ED in Hong Kong, adult patients aged 18years or older admitted to the resuscitation room or high dependency unit were recruited...
November 3, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29100094/de-novo-mutations-in-slc25a24-cause-a-disorder-characterized-by-early-aging-bone-dysplasia-characteristic-face-and-early-demise
#3
Karin Writzl, Ales Maver, Lidija Kovačič, Paula Martinez-Valero, Laura Contreras, Jorgina Satrustegui, Marco Castori, Laurence Faivre, Pablo Lapunzina, André B P van Kuilenburg, Slobodanka Radović, Christel Thauvin-Robinet, Borut Peterlin, Araceli Del Arco, Raoul C Hennekam
A series of simplex cases have been reported under various diagnoses sharing early aging, especially evident in congenitally decreased subcutaneous fat tissue and sparse hair, bone dysplasia of the skull and fingers, a distinctive facial gestalt, and prenatal and postnatal growth retardation. For historical reasons, we suggest naming the entity Fontaine syndrome. Exome sequencing of four unrelated affected individuals showed that all carried the de novo missense variant c.649C>T (p.Arg217Cys) or c.650G>A (p...
November 2, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29076104/objective-measurement-of-gestalts-quantifying-grouping-effect-by-tilt-aftereffect
#4
Ning Wei, Tiangang Zhou, Lin Chen
The importance of holistic perception is described by Gestalt psychology and its principles. Gestalt psychologists have promoted a formal and testable framework for these principles. Quantitative measurements have been introduced from Gestalt psychology in order to complement traditional phenomenal descriptions. Here we demonstrated a new method of measuring grouping effects objectively and quantitatively, by means of tilt aftereffect (TAE) from visual adaptation. Experiment 1 validated the method by measuring grouping based on either proximity or color similarity...
October 26, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/29075220/gestalt-theory-rearranged-back-to-wertheimer
#5
REVIEW
Shelia Guberman
Wertheimer's seminal paper of 1923 was of gerat influence in psychology and other sciences. Wertheimer also emphasized the weaknesses of the newborn Gestalt theory: too many basic laws, and the ambiguity of definitions. At the same time, the paper contained potential solutions to these problems, in the form of a number of very important ideas, some of which were presented implicitly: perception through imitation, communicative nature of linear drawings and writings, transfer from the visual domain to motor domain, linguistic interpretation of the Gestalt...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29055608/qualitative-study-to-understand-ordering-of-ct-angiography-to-diagnose-pulmonary-embolism-in-the-emergency-room-setting
#6
Soterios Gyftopoulos, Silas W Smith, Emma Simon, Masha Kuznetsova, Leora I Horwitz, Danil V Makarov
PURPOSE: To better understand the decision making behind the ordering of CT pulmonary angiography (CTPA) for the diagnosis of pulmonary embolism (PE) in the emergency department. METHODS: We conducted semistructured interviews with our institution's emergency medicine (EM) providers and radiologists who read CTPAs performed in the emergency department. We employed the Theoretical Domains Framework-a formal, structured approach used to better understand the motivations and beliefs of physicians surrounding a complex medical decision making-to categorize the themes that arose from our interviews...
October 18, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29045537/toxicity-adjustment-in-the-esmo-mcbs-a-diligent-process-of-data-interpretation-with-peer-review-that-is-far-from-gestalt
#7
N I Cherny, U Dafni, J Bogaerts, N J Latino, G Pentheroudakis, J-Y Douillard, J Tabernero, C Zielinski, M J Piccart, E G E de Vries
No abstract text is available yet for this article.
October 12, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29044227/accuracy-of-weight-estimation-by-the-broselow-tape-is-substantially-improved-by-including-a-visual-assessment-of-body-habitus
#8
Mike Wells, Lara Goldstein, Alison Bentley
BackgroundThe Broselow tape (BT) has been shown to estimate weight poorly primarily because of variations in body habitus. The manufacturers have suggested that a visual assessment of habitus may be used to increase its performance. This study evaluated the ability of habitus-modified models to improve the accuracy thereof.MethodsA post hoc analysis of prospectively collected data from four hospitals in Johannesburg, South Africa, on a population of 1,085 children. Sixteen a priori models generated a modified weight estimation or drug dose based on the BT weight and a gestalt assessment of habitus...
October 18, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29039752/aesthetic-diagnosis-in-gestalt-therapy
#9
Jan Roubal, Gianni Francesetti, Michela Gecele
The diagnostic process in psychotherapy using the aesthetic evaluation is described in this article. Unlike the classical diagnostic process, which presents a result of comparing clinicians´ observations with a diagnostic system (DSM, ICD, etc.), the aesthetic evaluation is a pre-reflexive, embodied, and preverbal process. A Gestalt Therapy theoretical frame is used to introduce a concept of the aesthetic diagnostic process. During this process, the clinicians use their own here-and-now presence, which takes part in the co-creation of the shared relational field during the therapeutic session...
October 17, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/29018000/waveform-capnography-an-alternative-to-physician-gestalt-in-determining-optimal-intubating-conditions-after-administration-of-paralytic-agents
#10
Anthony Scoccimarro, Jason R West, Marc Kanter, Nicholas D Caputo
PURPOSE: We sought to evaluate the utility of waveform capnography (WC) in detecting paralysis, by using apnoea as a surrogate determinant, as compared with clinical gestalt during rapid sequence intubation. Additionally, we sought to determine if this improves the time to intubation and first pass success rates through more consistent and expedient means of detecting optimal intubating conditions (ie, paralysis). METHODS: A prospective observational cohort study of consecutively enrolled patients was conducted from April to June 2016 at an academic, urban, level 1 trauma centre in New York City...
October 10, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28972842/culture-and-development-a-systematic-relationship
#11
Heidi Keller
This article argues that the relationships between culture and development are differential and systematic. Therefore the presentation of the Western middle-class developmental pathway in textbooks as universal is grossly neglecting the reality and the psychologies of the majority of the world' s population. First, the conception of culture as the representation of environmental conditions is presented. The level of formal education acts as organizer of social milieus that define different learning environments for children...
September 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28967777/pseudo-set-framing
#12
Kate Barasz, Leslie K John, Elizabeth A Keenan, Michael I Norton
Pseudo-set framing-arbitrarily grouping items or tasks together as part of an apparent "set"-motivates people to reach perceived completion points. Pseudo-set framing changes gambling choices (Study 1), effort (Studies 2 and 3), giving behavior (Field Data and Study 4), and purchase decisions (Study 5). These effects persist in the absence of any reward, when a cost must be incurred, and after participants are explicitly informed of the arbitrariness of the set. Drawing on Gestalt psychology, we develop a conceptual account that predicts what will-and will not-act as a pseudo-set, and defines the psychological process through which these pseudo-sets affect behavior: over and above typical reference points, pseudo-set framing alters perceptions of (in)completeness, making intermediate progress seem less complete...
October 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28950299/toxicity-adjustment-in-the-esmo-mcbs-a-gestalt-approach
#13
J C Del Paggio
No abstract text is available yet for this article.
September 18, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28941558/emergency-medicine-evaluation-of-community-acquired-pneumonia-history-examination-imaging-and-laboratory-assessment-and-risk-scores
#14
Brit Long, Drew Long, Alex Koyfman
BACKGROUND: Pneumonia is a common infection, accounting for approximately one million hospitalizations in the United States annually. This potentially life-threatening disease is commonly diagnosed based on history, physical examination, and chest radiograph. OBJECTIVE: To investigate emergency medicine evaluation of community-acquired pneumonia including history, physical examination, imaging, and the use of risk scores in patient assessment. DISCUSSION: Pneumonia is the number one cause of death from infectious disease...
November 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28934384/short-syndrome-due-to-a-novel-de-novo-mutation-in-prkce-protein-kinase-c%C3%A9-impairing-torc2-dependent-akt-activation
#15
Diana Alcantara, Frances Elmslie, Martine Tetreault, Eric Bareke, Taila Hartley, Jacek Majewski, Kym Boycott, A Micheil Innes, David A Dyment, Mark O'Driscoll
SHORT syndrome is a rare, recognizable syndrome resulting from heterozygous mutations in PIK3R1 encoding a regulatory subunit of phosphoinositide-3-kinase (PI3K). The condition is characterized by short stature, intrauterine growth restriction, lipoatrophy and a facial gestalt involving a triangular face, deep set eyes, low hanging columella and small chin. PIK3R1 mutations in SHORT syndrome result in reduced signaling through the PI3K-AKT-mTOR pathway. We performed whole exome sequencing for an individual with clinical features of SHORT syndrome but negative for PIK3R1 mutation and her parents...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28924628/a-recurrent-neural-model-for-proto-object-based-contour-integration-and-figure-ground-segregation
#16
Brian Hu, Ernst Niebur
Visual processing of objects makes use of both feedforward and feedback streams of information. However, the nature of feedback signals is largely unknown, as is the identity of the neuronal populations in lower visual areas that receive them. Here, we develop a recurrent neural model to address these questions in the context of contour integration and figure-ground segregation. A key feature of our model is the use of grouping neurons whose activity represents tentative objects ("proto-objects") based on the integration of local feature information...
December 2017: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/28921731/interobserver-agreement-in-pediatric-cervical-spine-injury-assessment-between-prehospital-and-emergency-department-providers
#17
Lorin R Browne, Hamilton Schwartz, Fahd A Ahmad, Michael Wallendorf, Nathan Kuppermann, E Brooke Lerner, Julie C Leonard
BACKGROUND: Investigators have derived cervical spine injury (CSI) decision support tools from physician observations. There is a need to demonstrate that prehospital emergency medical services (EMS) providers can use these tools to appropriately determine the need for spinal motion restrictions and make field disposition decisions. OBJECTIVES: The objective was to determine the interobserver agreement between EMS and emergency department (ED) providers for CSI risk assessment variables and overall gestalt for CSI in children after blunt trauma...
September 18, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28899182/cognitive-humanistic-psychodynamics-sidney-blatt-s-theoretical-philosophical-legacy
#18
Golan Shahar, Linda C Mayes
A number of broad-based, theoretical-philosophical tenets are to be gleaned from Sidney Blatt's voluminous, extensive, and unique scholarly work. Dominant themes in Blatt's life and work include (1) his fascination with cognition, particularly mental maps, or representations, of reality; (2) the influence of humanistic values (e.g., agency, need for growth, gestalts, need for balance, and an optimistic focus on resilience); and (3) a steadfast adherence to Freud's revolutionary discovery of the dynamic unconscious...
June 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28879457/combining-local-and-global-cues-to-motion
#19
Michael Morgan
A spinning, moving object, such as a football with a surface texture, combines motion signals from rotation and translation. The interaction between these two kinds of signal was studied psychophysically with moving, circular clouds of dots, which also could move within the cloud. If the cloud moved near-vertically downwards but the dots within it moved obliquely, the apparent path of the cloud was attracted to that of the dots, as previously demonstrated with moving Gabor patches (Tse & Hseih Vision Research, 46, 3881-3885, 2006; Lisi & Cavanagh Current Biology, 25, 2535-40, 2015)...
October 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28844262/clinical-decision-aids-or-clinician-gestalt-hard-to-know-which-is-better-september-2017-annals-of-emergency-medicine-journal-club
#20
Deborah J Williams, Robert L Wears
No abstract text is available yet for this article.
September 2017: Annals of Emergency Medicine
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