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Nina Brawanski, Peter Baumgarten, Jürgen Konczalla, Volker Seifert, Christian Senft
BACKGROUND: Intracerebral foreign body granuloma is rarely reported. We present the case of a male patient with a cerebral foreign body granuloma. CASE DESCRIPTION: Initial admission of a 67-year-old male patient was after an aphasia followed by secondary generalized seizures. Cranial computed tomography (CCT) showed a metal-dense, wedge-shaped foreign body in the range of the frontal sinus on the left side, breaking through the frontal sinus, and creating a connection to the frontal cerebral lobe...
2016: Surgical Neurology International
Jamie Hacker Hughes, Amra Saleem Rao, Neelam Dosanjh, Esther Cohen-Tovée, Jeremy Clarke, Gita Bhutani
The performance culture of the health service means that the psychological well-being of staff is becoming paramount in maintaining the workforce and in sustaining psychological health and morale. A Charter for Psychological Staff Wellbeing and Resilience is introduced that puts the onus on us and on employers to make the necessary adjustments to their workplace cultures and encourage professionals - us - to break through the barrier of stigma.
December 2016: British Journal of Psychiatry: the Journal of Mental Science
Corinne Beerle, Hans Gelpke, Stefan Breitenstein, Ralph F Staerkle
BACKGROUND: We report a case of a rare complication of acute appendicitis with perforation through the abdominal wall. The case points out that an intraabdominal origin should be considered in patients presenting with rapidly spreading soft tissue infections of the trunk. CASE PRESENTATION: A 58-year-old European woman presented to our hospital with a 1-week history of severe abdominal pain accompanied by rapidly spreading erythema and emphysema of the lower abdomen...
December 1, 2016: Journal of Medical Case Reports
Daral J Jackwood, Simone T Stoute, Beate M Crossley
Infectious bursal disease virus (IBDV) contains two genome segments (segment A/segment B) that can reassort among the viruses. Reassortant IBDVs have been identified in several countries including the United States. These reassortant viruses usually include at least one genome segment from a very virulent (vv)IBDV strain. In vivo virulence of six reassortant IBDV from the United States was assessed relative to the virulence of three frequently described IBDV pathotypes: vvIBDV (rB strain), classic virulent (cv)IBDV (STC strain), and subclinical (sc)IBDV (Del-E strain)...
December 2016: Avian Diseases
Jing Fang, Minhao Wang, Bing Shen, Luqing Zhang, Daohui Lin
To date mechanisms underlying co-transports of engineered nanomaterials (ENMs) with contaminants have not been adequately explored, which involve complex interactions among ENMs, contaminants, and soils. This study investigated co-transport behaviors of 3 oxidized-multiwalled carbon nanotubes (o-MWCNTs) with phenanthrene (PHE) and oxytetracycline (OTC) in soil and sediment columns. Sorptions and desorptions of PHE and OTC by the o-MWCNTs were examined to facilitate the discussion of co-transport mechanisms...
January 1, 2017: Water Research
Ping Xu, Xia Yuan, Haixuan Huang, Tuo Yang, Yanyan Huang, Tengfei Zhu, Shaotuo Tang, Wenda Peng
An azimuth-tuned tri-color shift device based on an embedded subwavelength one-dimensional rectangular structure with single period is proposed. High reflection efficiencies for both TE and TM polarizations can be achieved simultaneously. Under an oblique incidence of 60°, the reflection efficiencies can reach up to 85, 86, and 100 % in blue (azimuth of 24°), green (azimuth of 63°), and red (azimuth of 90°) waveband, respectively. Furthermore, the laws of influence of device period, groove depth, coating thickness, and incident angle on reflection characteristics are investigated and exposed, and feasibility of the device is demonstrated...
December 2016: Nanoscale Research Letters
Steve den Hollander, James Brown, Michael Lambert, Paul Treu, Sharief Hendricks
The ability of the attacking team to break through the defensive line is a key indicator of success as it creates opportunities to score tries. The aim of this study was to analyse line breaks and identify the associated skills and playing characteristics. The 2013 Super Rugby season (125 games) was analysed, in which 362 line breaks were identified and coded using variables that assessed team patterns and non-contact attacking skills in the phases preceding the line break. There was an average of 3 line breaks per game, with 39% of line breaks resulting in a try...
September 2016: Journal of Sports Science & Medicine
David L Osborn, Carl C Hayden, Patrick Hemberger, Andras Bodi, Krisztina Voronova, Bálint Sztáray
Photoelectron Photoion Coincidence (PEPICO) spectroscopy holds the promise of a universal, isomer-selective, and sensitive analytical technique for time-resolved quantitative analysis of bimolecular chemical reactions. Unfortunately, its low dynamic range of ∼10(3) has largely precluded its use for this purpose, where a dynamic range of at least 10(5) is generally required. This limitation is due to the false coincidence background common to all coincidence experiments, especially at high count rates. Electron/ion pairs emanating from separate ionization events but arriving within the ion time of flight (TOF) range of interest constitute the false coincidence background...
October 28, 2016: Journal of Chemical Physics
Carla J L Atkinson, Kyle J Martin, Gareth J Fraser, Shaun P Collin
Gustation in sharks is not well understood, especially within species that ingest food items using suction. This study examines the morphological and immunohistochemical characterisation of taste papillae and oral denticles in the oropharynx of the brown-banded bamboo shark Chiloscyllium punctatum and compares their distribution during development. Taste papillae of the brown-banded bamboo shark Chiloscyllium punctatum are located throughout the oropharyngeal region and are most concentrated on the oral valves (2,125-3,483 per cm(2) in embryos; 89-111 per cm(2) in mature adults) close to the tooth territories...
October 26, 2016: Biology Open
Yiming Zhao, Nong Zhang, Guangyao Si
Monitoring of roof activity is a primary measure adopted in the prevention of roof collapse accidents and functions to optimize and support the design of roadways in underground coalmines. However, traditional monitoring measures, such as using mechanical extensometers or electronic gauges, either require arduous underground labor or cannot function properly in the harsh underground environment. Therefore, in this paper, in order to break through this technological barrier, a novel monitoring system for roof safety control in underground coal mining, using fiber Bragg grating (FBG) material as a perceived element and transmission medium, has been developed...
October 21, 2016: Sensors
David F Tough, Paul P Tak, Alexander Tarakhovsky, Rab K Prinjha
Immune-mediated diseases are clinically heterogeneous but they share genetic and pathogenic mechanisms. These diseases may develop from the interplay of genetic factors and environmental or lifestyle factors. Exposure to such factors, including infectious agents, is associated with coordinated changes in gene transcription owing to epigenetic alterations. A growing understanding of how epigenetic mechanisms control gene expression patterns and cell function has been aided by the development of small-molecule inhibitors that target these processes...
October 21, 2016: Nature Reviews. Drug Discovery
Petra Žádníková, Krzysztof Wabnik, Anas Abuzeineh, Marçal Gallemi, Dominique Van Der Straeten, Richard S Smith, Dirk Inzé, Jiří Friml, Przemysław Prusinkiewicz, Eva Benková
Differential cell growth enables flexible organ bending in the presence of environmental signals such as light or gravity. A prominent example of the developmental processes based on differential cell growth is the formation of the apical hook that protects the fragile shoot apical meristem when it breaks through the soil during germination. Here, we combined in silico and in vivo approaches to identify a minimal mechanism producing auxin gradient-guided differential growth during the establishment of the apical hook in the model plant Arabidopsis thaliana Computer simulation models based on experimental data demonstrate that asymmetric expression of the PIN-FORMED auxin efflux carrier at the concave (inner) versus convex (outer) side of the hook suffices to establish an auxin maximum in the epidermis at the concave side of the apical hook...
October 2016: Plant Cell
Jiawei Guan, Qian Zhao, Weifeng Mao
PTEN is a tumor suppressor gene characterized as a phosphatase that antagonizes the phosphatidylinositol 3-kinase signaling pathway in the cytoplasm. Nuclear PTEN plays roles in chromosomal stability, in which the double-strand breaks (DSB) repair mediated by homologous recombination (HR) and non-homologous end joining (NHEJ) is critical. Herein, the role of nuclear PTEN in DSB repair and the underlying molecular mechanism was investigated in this study. Using human breast cancer BT549 and MDA-MB-231 cell lines, we reveal a specific feature of PTEN that controls poly(ADP-ribosyl)ation of Ku70 and interferes with binding of Ku70 at DSB...
December 2016: Biochimica et Biophysica Acta
A Heratizadeh, T Werfel
The pathogenesis of atopic dermatitis (AD) is multifactorial and complex. Consequently, clinical signs and symptoms vary strongly depending on individually relevant trigger factors and the stage of the disease. So far, treatment of AD was commonly limited to topical treatment or, in more severe cases, to systemic drugs mostly approved for other indications than AD. However, emerging data on new anti-inflammatory agents have been published in the recent years. As these new substances specifically focus on immune responses in AD, these are partially considered as possible 'breakthrough' in the treatment of AD...
December 2016: Allergy
Mousumi Chatterjee, Bhavya Srivastava, Milan K Barman, Bhabatosh Mandal
A time-cost effective, chemically stable mesoporous resin (FSG-PAN), simultaneous binder of two different metal centers (both high (Cd(II)) and low (Tl(I)) oxidation states), has been synthesized by immobilizing azo-dye (1-(2-pyridylazo)-2-napthol: PAN) on functionalized silica gel (FSG). Its corresponding synthesized nano material possesses good luminescent properties, and has been utilized in fluoride sensing at trace levels (1.8 × 10(-6) - 7.2 × 10(-6) M). The composition ({Si[OSi]p=4[H2O]x=0.81}12[-Si(CH3)2-NH-C6H4-N=N-PAN]4...
2016: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
Joo Hwan Oh, Badreddine Assouar
Metamaterials realizing stop bands have attracted much attentions recently since they can break-through the well-known mass law. However, achieving the stop band at extremely low frequency has been still a big challenge in the fields of elastic metamaterials. In this paper, we propose a new metamaterial based on the idea of the zero rotational stiffness, to achieve extremely low frequency stop band for flexural elastic waves. Unlike the previous ways to achieve the stop band, we found that the zero rotational stiffness can provide a broad stop band at extremely low frequency, which starts from even almost zero frequency...
2016: Scientific Reports
Mohammad Abdelghani, Patrick W Serruys
The earliest evidence supporting transcatheter aortic valve implantation (TAVI) was derived from its comparison with conservative therapy in inoperable patients and with surgical aortic valve replacement (SAVR) in extremely high risk patients. TAVI had a relative advantage in these situations being less invasive and hence less prone to the classic early postoperative devastating complications. To prove as effective in less fragile and less morbid patients, the long-term durability of the haemodynamic and clinical gains from TAVI needs to be confirmed...
September 18, 2016: EuroIntervention
Shen Xu, Runfeng Chen, Chao Zheng, Wei Huang
Organic afterglow materials, developed recently by breaking through the difficulties in modulating ultrafast-decayed excited states, exhibit ultralong-lived emission for persistent luminescence with lifetimes of several orders of magnitude longer than traditional fluorescent and phosphorescent emissions at room temperature. Their exceptional properties, namely ultralong luminescent lifetime, large Stokes shifts, facile excited state transformation, and environmentally sensitive emission, have led to a diverse range of advanced optoelectronic applications...
December 2016: Advanced Materials
Christoph Flückiger, Hansjörg Znoj, Andreea Vîslă
Since the programmatic Rosenhan study, there is a broad discussion of how to actively construct clinical realities on both "insane" and "sane" perspectives. To inform patients about the output of the psychometric questionnaires assessed at intake is a required task in many clinical routines. Information processing bias toward psychopathology may impact many clinical communications and thus lead to clinical errors. Based on an output of the commonly used Symptom Check List 90, case examples demonstrate various grades of balanced and unbalanced alternatives of how to consider the psychopathological as well as the unproblematic poles of Likert scales in discussing psychometric questionnaires at Session 1...
September 2016: Psychotherapy
Jennifer M Black, Mengyang Zhu, Pengfei Zhang, Raymond R Unocic, Daqiang Guo, M Baris Okatan, Sheng Dai, Peter T Cummings, Sergei V Kalinin, Guang Feng, Nina Balke
Atomic force microscopy (AFM) force-distance measurements are used to investigate the layered ion structure of Ionic Liquids (ILs) at the mica surface. The effects of various tip properties on the measured force profiles are examined and reveal that the measured ion position is independent of tip properties, while the tip radius affects the forces required to break through the ion layers as well as the adhesion force. Force data is collected for different ILs and directly compared with interfacial ion density profiles predicted by molecular dynamics...
2016: Scientific Reports
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