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Alexander J Baldwin
Mollie Lentaigne was a medical artist who worked at the Queen Victoria Hospital in East Grinstead during the Second World War alongside Archibald McIndoe and his dedicated team. She drew hundreds of medical illustrations for McIndoe and his fellow surgeons during the years between 1940 and 1945. Her illustrations depict the plastic surgery that was carried out in that hospital on the badly burnt RAF servicemen injured during the war that took place in the skies over Europe, which included many aircrew injured during the Battle of Britain...
April 16, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Harmen Zijlstra, Scott Collins, Jason Scott McIndoe
The anions formed from methylalumoxane (MAO) and suitable donors (e.g. octamethyltrisiloxane) are amenable to mass spectrometric (MS) analysis. Their composition as deduced from this data allows direct insight into the chemical transformations of their neutral precursors. One such process is oxidation, which is well-known to be facile for MAO without any clear idea of what actually occurs at a molecular level. Addition of O2 to MAO results in immediate gelation, but MS analysis reveals no corresponding change to the composition of the principal oligomeric anions...
January 17, 2018: Chemistry: a European Journal
Stefan Mitzinger, Jascha Bandemehr, Kevin Reiter, J Scott McIndoe, Xiulan Xie, Florian Weigend, John F Corrigan, Stefanie Dehnen
The novel binary P4 analogue (Ge2 P2 )2- proved to be a suitable precursor for heteroatomic cluster synthesis. Over time in solution, it rearranges to form (Ge7 P2 )2- , as shown by NMR studies and X-ray diffraction. Reactions of (Ge2 P2 )2- with CdPh2 afford [K(crypt-222)]3 [Cd3 (Ge3 P)3 ], containing an unprecedented ternary cluster anion with a triangular Cd3 moiety.
February 6, 2018: Chemical Communications: Chem Comm
Darien Yeung, Johanne Penafiel, Harmen S Zijlstra, J Scott McIndoe
Reduction of red Cp2 TiCl2 (Cp = cyclopentadienyl) with zinc dust in acetonitrile produces a blue solution of [Cp2 Ti(NCMe)2 ]+ , which when exposed to air rapidly discolors to bright yellow. This behavior makes the blue solution a handy visual indicator for the presence of oxygen, but the chemistry is considerably more complicated than the primary colors suggest at first glance. Real-time mass spectrometric and colorimetric analysis reveals that oxidation from Ti(III) to Ti(IV) produces a host of oxygen-containing complexes, whose appearance parallels the observed color changes...
January 2, 2018: Inorganic Chemistry
A O Wamalwa, T Stasch, F W Nangole, S O Khainga
Reduction mammaplasty is the volumetric reduction in the bulk of the breast. Techniques have evolved from primarily reducing the breast bulk to reducing with emphasis on functional and aesthetic outcome. The deeper understanding of the surgical anatomy of the breast has guided this development. While Paulus Aegina (sixth century AD), Dieffenbach (1848) and Gaillard-Thomas (1882) set the pace in glandular reduction; Pousson (1897) and Dehner (1908) focused on breast ptosis. It took quite some time before the enigma of the vascularization to the nipple areolar complex could be solved...
March 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
Musa Kayondo, Joseph Njagi, Peter Kivuniike Mukasa, Tom Margolis
BACKGROUND: Although vaginal agenesis as may occur in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare condition, it is associated with not only anatomical problems but also serious psychological and social problems like painful sexual intercourse, primary amenorrhea and infertility. Surgery, which is aimed at reconstruction of a vagina of adequate length and width to serve the function, is the main method of treatment. Many methods for vaginal reconstruction have been described but each has its complications and limitations...
August 29, 2017: BMC Urology
Haoxuan Zhu, Eric Janusson, Jingwei Luo, James Piers, Farhana Islam, G Bryce McGarvey, Allen G Oliver, Ori Granot, J Scott McIndoe
Bromobenzyl compounds react selectively with phenols via the Williamson ether synthesis. An imidazolium charge-tagged bromobenzyl compound can be used to reveal phenol impurities in jet fuel by analysis via electrospray ionization mass spectrometry. The complex matrix as revealed by Cold EI GC/MS analysis is reduced to a few simple sets of compounds in the charge-tagged ESI mass spectrum, primarily substituted phenols and thiols. Examination of jet fuels treated by different refinery methods reveals the efficacy of these approaches in removing these contaminants...
August 9, 2017: Analyst
So-Eun Han, Ju Young Go, Doo Seok Choi, Gi Hong Seo, So Young Lim
INTRODUCTION: Appropriate postoperative care and prolonged use of the mold are prerequisites for achieving successful results in McIndoe-style vaginoplasty. OBJECTIVE: We introduce a specially designed pored polyacetal mold to maintain the reconstructed vagina, with favorable long-term results allowing drainage of the serous and bloody discharge without removal of the mold, and reduction of infection rate and the chance of skin graft shearing in McIndoe vaginoplasty...
December 2017: Journal of Pediatric Urology
Shiv S Kaundun, Sarah-Jane Hutchings, Richard P Dale, Anushka Howell, James A Morris, Vance C Kramer, Vinod K Shivrain, Eddie Mcindoe
Amaranthus tuberculatus is a troublesome weed in corn and soybean production systems in Midwestern USA, due in part to its ability to evolve multiple resistance to key herbicides including 4-hydroxyphenylpyruvate dioxygenase (HPPD). Here we have investigated the mechanism of resistance to mesotrione, an important chemical for managing broadleaf weeds in corn, in a multiple herbicide resistant population (NEB) from Nebraska. NEB showed a 2.4-fold and 45-fold resistance increase to mesotrione compared to a standard sensitive population (SEN) in pre-emergence and post-emergence dose-response pot tests, respectively...
2017: PloS One
M Zayed, R Fouad, K A Elsetohy, A T Hashem, A A AbdAllah, A I Fathi
STUDY OBJECTIVE: The objective of this study was to assess short-term benefits and risks of utero-vaginal anastomosis done for cases of cryptomenorrhea due to cervical atresia with vaginal aplasia. DESIGN: Prospective study. SETTING: Surgical procedures were done between December 2013 and September 2015 at the department of Obstetrics and Gynecology, Cairo University Hospital. PARTICIPANTS: Five patients who had cryptomenorrhea due to cervical atresia associated with vaginal aplasia were included...
December 2017: Journal of Pediatric and Adolescent Gynecology
Richa Vatsa, Juhi Bharti, Kallol Kumar Roy, Sunesh Kumar, Jai Bhagwan Sharma, Neeta Singh, Seema Singhal, Jyoti Meena
OBJECTIVE: To assess the outcome of amnion vaginoplasty in cases of vaginal agenesis due to Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome managed at the authors' institution. DESIGN: Retrospective study. SETTING: Tertiary care hospital. PATIENT(S): Fifty women with MRKH who underwent neovaginoplasty. INTERVENTION(S): Modified McIndoe's vaginoplasty was done in all the patients, using human amnion graft...
August 2017: Fertility and Sterility
Abdulrahim Gari
OBJECTIVES: To evaluate the surgical feasibility and the long-term anatomical and functional results and complication rates in patients with Mullerian aplasia who underwent vaginal reconstruction. METHODS: A retrospective observational case series study over 8 years was conducted in King Faisal Specialist Hospital & Research Centre - Jeddah, Saudi Arabia. All cases diagnosed as Mullerian aplasia and who underwent surgical correction were included. Painless and satisfactory vaginal intercourse after surgery were the main outcome measured...
January 2017: Pakistan Journal of Medical Sciences Quarterly
Vineet Mishra, Suwa Ram Saini, Sakshi Nanda, Sumesh Choudhary, Priyankur Roy, Tanvir Singh
The presence of cervicovaginal agenesis with unicornuate uterus is a very rare mullerian anomaly. Its true incidence is still unknown. The presence of functioning unicornuate uterus poses a great challenge for a gynecologist because a successful repair could restore normal menses and may preserve a patient's fertility. Hence, we report a case of 16-year-old unmarried female who presented with chief complaints of primary amenorrhea with cyclical lower abdominal pain. On clinical and radiological evaluation, she was diagnosed with complete cervicovaginal agenesis with right unicornuate uterus (hematometra and hematosalpinx)...
October 2016: Journal of Human Reproductive Sciences
Guilherme Lang Motta, Patric Machado Tavares, Gabriel Veber Moisés Silva, Milton Berger, Brasil Silva, Tiago Elias Rosito
INTRODUCTION: The ideal vaginoplasty method should promote good cosmetic and functional results with low morbidity. We describe a new technique for congenital vaginal agenesis using a full-thickness perforated skin graft. MATERIALS AND METHODS: We report an 18 year old patient with vaginal agenesis (Morris syndrome) that undergone a modified version of McIndoe vaginoplasty. Patient is set in a low lithotomy position and lateral traction sutures are placed in labia and a 16Fr urethral catheter inserted...
November 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Eric Janusson, Harmen S Zijlstra, Peter P T Nguyen, Landon MacGillivray, Julio Martelino, J Scott McIndoe
A combination of UV-Vis spectroscopy and electrospray ionization mass spectrometry is used for real-time monitoring of Pd2 (dba)3 activation with sulfonated versions of PPh3 and Buchwald-type ligands. This provides insight into the effect of ligand and preparation conditions on activation and allows for establishment of rational activation protocols.
January 10, 2017: Chemical Communications: Chem Comm
Johanne Penafiel, Amelia V Hesketh, Ori Granot, J Scott McIndoe
Electron ionization (EI) is a reliable mass spectrometric method for the analysis of the vast majority of thermally stable and volatile compounds. In direct EI-MS, the sample is placed into the probe and introduced to the source. For air- and moisture-sensitive organometallic complexes, the sample introduction step is critical. A small quantity must be briefly exposed to the atmosphere, during which time decomposition can occur. Here we present a simple tool that allows convenient analysis of air- and moisture-sensitive organometallic species by direct probe methods: a small purge-able glove chamber affixed to the front end of the mass spectrometer...
October 4, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Oya Soylu Karapınar, Mustafa Özkan, Ayşe Güler Okyay, Hanifi Şahin, Kenan Serdar Dolapçıoğlu
OBJECTIVE: Retrospective analysis of cases that have undergone neovagina operation because of congenital vaginal agenesis was objected. MATERIAL AND METHODS: Seven cases applying with the complaints of primary amenorrhea or inability to have sexual intercourse were in the study. The cases were diagnosed with congenital vaginal agenesis and operated at Mustafa Kemal University Training and Research Hospital between 2011 and 2014. Vaginoplasty by the modified McIndoe method was performed in all cases...
2016: Journal of the Turkish German Gynecological Association
Eric Janusson, G Bryce McGarvey, Farhana Islam, Christine Rowan, J Scott McIndoe
A simple chemical derivatization technique was developed for electrospray ionization mass spectrometry (ESI-MS) in which thiols and disulfides may be selectively analyzed in a complex matrix and easily characterized. These reagents enhance detection of thiols and disulfides solely due to the nature of the charge-tag derivatization agent and therefore does not require an isotopically labelled substrate. The charged disulfides readily and exclusively react with thiols in a complex matrix in a short amount of time...
October 7, 2016: Analyst
Brijesh Mishra, Gaurav Janavar, Yashodhara Pradeep, Arun K Singh, Vijay Kumar, Divya N Upadhyay
Absence of vagina poses multitude of physical and psychosocial problems in woman's life. 10% of Mayer- Rokitansky-üster-Hauser (MRKH) syndrome patients with high vaginal septum and vaginal atreisa has additional issue of draining uterine cavity. MC Indoe vaginoplasty is universally acceptable and widely practiced procedure for neocolposis reconstruction. Simultaneous reconstruction of vagina with simultaneous continued uterine drainage presents surgical challenge. We offer a simple solution of creating a vaginal mould using a 10 ml disposable syringe, which enables graft application of neovaginal cavity with simultaneous protected uterine drainage per vaginum...
January 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
P J Siddall, L McIndoe, P Austin, P J Wrigley
STUDY DESIGN: The study uses a cross-sectional, group comparison, questionnaire-based design. OBJECTIVES: To determine whether spinal cord injury and pain have an impact on spiritual well-being and whether there is an association between spiritual well-being and measures of pain and psychological function. SETTING: University teaching hospital in Sydney, New South Wales, Australia. METHODS: Questionnaires evaluating pain, psychological and spiritual well-being were administered to a group of people with a spinal cord injury (n=53) and a group without spinal cord injury (n=37)...
January 2017: Spinal Cord
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