keyword
https://read.qxmd.com/read/38537121/influence-of-low-level-tannin-supplementation-on-comparative-growth-performance-of-holstein-and-angus-x-holstein-cross-calf-fed-concentrate-based-finishing-diets-for-328-days
#21
JOURNAL ARTICLE
Pedro H V Carvalho, Brooke C Latack, Marcos V C Ferraz, Lester J R P Nolasco, Willi R Meireles, Heitor O M Oliveira, Richard A Zinn
The objective of the current study was to evaluate the effects of tannin and monensin supplementation in feedlot diets and breed (Holstein vs. Angus × Holstein) on growth performance, energetic efficiency, and carcass characteristics. Eighty purebred Holstein calves (HOL; initial body weight (BW) = 130 ± 5 kg) and eighty Angus × Holstein calves (AXH; initial BW = 129 ± 6 kg) were blocked by initial BW and randomly assigned to 40 pens. Dietary treatments consisted of a steam-flaked corn-based diet supplemented with 1) no feed additive (CON); 2) 30 mg of monensin/ kg of dry matter (DM) (MON; Rumensin 90, Elanco, Greenfield, IN); 3) 1...
March 27, 2024: Journal of Animal Science
https://read.qxmd.com/read/38537119/constructing-linear-oriented-pre-vascularized-human-spinal-cord-tissues-for-spinal-cord-injury-repair
#22
JOURNAL ARTICLE
Caixia Fan, Hui Cai, Lulu Zhang, Xianming Wu, Junyan Yan, Lifang Jin, Baowei Hu, Jiaxiong He, Yanyan Chen, Yannan Zhao, Jianwu Dai
Repairing spinal cord injury (SCI) is a global medical challenge lacking effective clinical treatment. Developing human-engineered spinal cord tissues that can replenish lost cells and restore a regenerative microenvironment offers promising potential for SCI therapy. However, creating vascularized human spinal cord-like tissues that mimic the diverse cell types and longitudinal parallel structural features of spinal cord tissues remains a significant hurdle. In present study, vascularized spinal cord tissues (VSCT) were engineered using embryonic human spinal cord-derived neural cells and endothelial cells on linear ordered collagen scaffolds (LOCS)...
March 27, 2024: Advanced Healthcare Materials
https://read.qxmd.com/read/38537116/featured-articles-for-cme-credit-april-2024
#23
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38537085/long-term-survival-outcomes-of-robotic-total-gastrectomy-for-locally-advanced-proximal-gastric-cancer-a-prospective-study
#24
JOURNAL ARTICLE
Qing Zhong, Yi-Hui Tang, Zhi-Yu Liu, Zhi-Quan Zhang, Qi-Chen He, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Chao-Hui Zheng, Chang-Ming Huang
BACKGROUND: Robotic gastrectomy is a safe and feasible approach for gastric cancer (GC); however, its long-term oncological efficacy remains unclear. We evaluated the long-term survival outcomes and recurrence patterns of patients with locally advanced proximal GC who underwent robotic total gastrectomy (RTG). METHODS: This prospective study (FUGES-014 study) enrolled 48 patients with locally advanced proximal GC who underwent RTG between March 2018 and February 2020 at a tertiary referral teaching hospital...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38537084/personal-versus-therapist-perioperative-music-intervention-a-randomized-controlled-trial
#25
JOURNAL ARTICLE
Fan Jiang, Tingting Wang, Liqiong Hu, Shangui Chen, Lijian Chen, Xuesheng Liu, Yao Lu, Erwei Gu, Luis Ulloa
INTRODUCTION: Music interventions can alleviate patient anxiety and improve post-surgical satisfaction. However, it remains uncertain whether music personal preferences affect efficacy. We tested whether personal music intervention with patient-selected songs played ad libitum is more effective than standard therapist-designed treatment with classical music. METHODS: A prospective, parallel-group, single-blinded, randomized controlled trial with 229 participants (aged 18 to 60 y) previously scheduled for elective surgery...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38537079/amino-acid-supplementation-confers-protection-to-red-blood-cells-prior-to-plasmodium-falciparum-bystander-stress
#26
JOURNAL ARTICLE
Heather Colvin Binns, Elmira Alipour, Cameron E Sherlock, Dinah S Nahid, John F Whitesides, Anderson O'Brien Cox, Cristina M Furdui, Glen S Marrs, Daniel B Kim-Shapiro, Regina Joice Cordy
Malaria is a highly oxidative parasitic disease in which anemia is the most common clinical symptom. A major contributor to malarial anemia pathogenesis is the destruction of bystander, uninfected red blood cells (RBCs). Metabolic fluctuations are known to occur in the plasma of individuals with acute malaria, emphasizing the role of metabolic changes in disease progression and severity. Here, we report that conditioned media from Plasmodium falciparum culture induces oxidative stress in uninfected, catalase-depleted RBCs...
March 27, 2024: Blood Advances
https://read.qxmd.com/read/38537069/controversies-in-terlipressin-and-transplantation-in-the-united-states-how-do-we-meld-the-two
#27
JOURNAL ARTICLE
Eric M Przybyszewski, Robert M Wilechansky, Paige McLean Diaz, Andrew S Allegretti, Lisa B VanWagner, Giuseppe Cullaro, Josh Levitsky, Pere Ginès, Salvatore Piano, Sumeet K Asrani, Kavish R Patidar
Hepatorenal syndrome-acute kidney injury (HRS-AKI) is a severe complication of cirrhosis that carries a poor prognosis. The recent Food and Drug Administration approval of terlipressin has substantial implications for managing HRS-AKI and liver allocation in the United States (US). Terlipressin has been available in Europe for over a decade, and several countries have adapted policy changes such as Model for End-Stage Liver Disease (MELD) score "lock" for HRS-AKI. In this article, we outline the European experience with terlipressin use and explore the question of whether terlipressin treatment for HRS-AKI should qualify for MELD score "lock" in the US in those who respond to therapy...
March 28, 2024: Liver Transplantation
https://read.qxmd.com/read/38537068/fear-of-recurrence-among-lung-cancer-survivors-a-theoretical-model-validation
#28
JOURNAL ARTICLE
Qiuhong Chen, Yunqin Weng, Fangfang Wang, Xiaoyan Yang, Wei-Ti Chen, Feifei Huang
BACKGROUND: Fear of cancer recurrence (FCR) significantly impacts the treatment and prognosis of lung cancer survivors. However, the mechanisms and factors contributing to FCR and its related consequences in lung cancer remain poorly understood. OBJECTIVE: To evaluate the validity of the Lee-Jones Theoretical Model of FCR in lung cancer survivors. METHODS: A cross-sectional survey was conducted among 257 lung cancer survivors who had undergone surgical treatment 1 year prior...
March 27, 2024: Cancer Nursing
https://read.qxmd.com/read/38537067/conventional-epithelial-off-corneal-crosslinking-in-patients-with-progressive-keratoconus-10-year-outcomes
#29
JOURNAL ARTICLE
Jérémy Bordais, Myriam Cassagne, David Touboul, Valentine Saunier, Jacqueline Butterworth, François Malecaze, Vincent Soler, Pierre Fournié
PURPOSE: Corneal crosslinking (CXL) is the standard treatment of progressive keratoconus (KC). We evaluated the safety and 10-year outcomes of conventional "epithelial-off" CXL for progressive KC for the first time in a cohort in France. METHODS: We conducted a retrospective review of patients undergoing conventional CXL (Dresden protocol) in our tertiary ophthalmology department from 2006 to 2011 with 10-year follow-up. The primary outcome was change in preoperative versus postoperative keratometry measured by maximum keratometry (Kmax), steep keratometry (K2), flat keratometry (K1), mean keratometry (Km), and topographic cylinder...
March 27, 2024: Cornea
https://read.qxmd.com/read/38537065/a-multicenter-study-of-venetoclax-based-treatment-for-patients-with-richter-transformation-of-chronic-lymphocytic-leukemia
#30
JOURNAL ARTICLE
Paul Joseph Hampel, Mahesh Swaminathan, Kerry A Rogers, Erin M Parry, Jan A Burger, Matthew S Davids, Wei Ding, Alessandra Ferrajoli, Jonathan Mitry Hyak, Nitin Jain, Saad S Kenderian, Yucai Wang, William G Wierda, Jennifer A Woyach, Sameer A Parikh, Philip A Thompson
Patients with chronic lymphocytic leukemia (CLL) who develop Richter transformation (RT) have a poor prognosis when treated with chemoimmunotherapy regimens used for de novo diffuse large B-cell lymphoma. Venetoclax, a BCL2 inhibitor, has single agent efficacy in patients with RT and is potentially synergistic with chemoimmunotherapy. In this multicenter, retrospective study, we evaluated 62 patients with RT who received venetoclax-based treatment outside of a clinical trial, in combination with a Bruton tyrosine kinase inhibitor (BTKi; n=28), R-CHOP (n=13), or intensive chemoimmunotherapy other than R-CHOP (n=21)...
March 27, 2024: Blood Advances
https://read.qxmd.com/read/38537062/late-cytomegalovirus-disease-after-hematopoietic-cell-transplantation-significance-of-novel-transplantation-techniques
#31
JOURNAL ARTICLE
Alicja Sadowska-Klasa, Sezen Özkök, Hu Xie, Wendy M Leisenring, Danniel Zamora, Sachiko Seo, Jordan Sheldon, Stephanie J Lee, Keith R Jerome, Margaret L Green, Michael J Boeckh
Pre-emptive therapy (PET) and letermovir prophylaxis are effective in preventing CMV disease within the first 100 days after allogeneic hematopoietic cell transplantation (HCT) but are associated with late-onset CMV disease. We retrospectively examined the clinical manifestations, risk factors, prevention algorithm, and outcome of late CMV disease in CMV seropositive day 100 survivors transplanted between 2001-2017 (PET cohort) and 2018-2021 (letermovir cohort). There were 187 episodes of late CMV disease among 2469 day 100 survivors and the estimated cumulative incidence of first late CMV disease was 6...
March 27, 2024: Blood Advances
https://read.qxmd.com/read/38537060/prognostic-factors-for-resected-cases-with-gallbladder-carcinoma-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Tian-Run Lv, Jun-Ke Wang, Fu-Yu Li, Hai-Jie Hu
OBJECTIVE: Current meta-analysis was performed to systematically evaluate the potential prognostic factors for overall survival (OS) among resected cases with gallbladder carcinoma (GBC). METHODS: PubMed, EMBASE, and the Cochrane Library were systematically retrieved and hazard ratio (HR) and its 95% confidence interval (CI) were directly extracted from the original study or roughly estimated via Tierney's method. Standard Parmar modifications were used to determine pooled HRs...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38537056/perioperative-outcomes-and-long-term-survival-of-cryosurgery-on-unresectable-pancreatic-cancer-a-systematic-review-and-meta-analysis
#33
JOURNAL ARTICLE
Kang Xue, Xiaofeng Liu, Xiaolin Xu, Li Wang, Bole Tian
BACKGROUND: Pancreatic cancer (PC) continues to rank as one of the deadliest forms of cancer, with the majority of patients being diagnosed with unresectable disease. The implementation of cryoablation-based comprehensive treatment is expected to lead to a reduction in tumor size and potentially achieve complete resection. However, the availability of systematic and evidence-based treatment guidelines for cryoablation in pancreatic cancer is currently limited. MATERIALS AND METHODS: A computerized search was conducted in the Medline, Embase, Cochrane Library databases, and Clinicaltrials to retrieve studies published from August 1987 to June 2023...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38537053/characterizing-the-opioidergic-mechanisms-of-repetitive-transcranial-magnetic-stimulation-induced-analgesia-a-randomized-controlled-trial
#34
JOURNAL ARTICLE
Ying Liu, Junfeng Sun, Chaomin Wu, Jinxuan Ren, Yanni He, Na Sun, Hao Huang, QunShan Chen, Dan Liu, Yangyuxin Huang, Feng Xu, Lina Yu, Bernadette M Fitzgibbon, Robin F H Cash, Paul B Fitzgerald, Min Yan, Xianwei Che
Repetitive transcranial magnetic stimulation (rTMS) is a promising technology to reduce chronic pain. Investigating the mechanisms of rTMS analgesia holds the potential to improve treatment efficacy. Using a double-blind and placebo-controlled design at both stimulation and pharmacologic ends, this study investigated the opioidergic mechanisms of rTMS analgesia by abolishing and recovering analgesia in 2 separate stages across brain regions and TMS doses. A group of 45 healthy participants were equally randomized to the primary motor cortex (M1), the dorsolateral prefrontal cortex (DLPFC), and the Sham group...
March 26, 2024: Pain
https://read.qxmd.com/read/38537044/toxoplasmosis-outbreak-in-s%C3%A3-o-paulo-brazil-epidemiology-and-visual-outcome
#35
JOURNAL ARTICLE
Luciana Peixoto Santos Finamor, Geraldine Madalosso, José Eduardo Levi, Yuslay Fernández Zamora, Gabriela Akemi Kamioka, Paula Marinho, Heloisa Nascimento, Cristina Muccioli, Rubens Belfort
PURPOSE: To describe a 2019 acute toxoplasmosis outbreak in the city of São Paulo, Brazil, and to evaluate the laboratory serological profile for toxoplasmosis for three consecutive years. The ophthalmological manifestations of the patients involved in the outbreak were also studied. METHODS: A cross-sectional descriptive study of a toxoplasmosis outbreak in São Paulo, Brazil, between February and May 2019. Epidemiological data were described, as were the observed ocular manifestations...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537043/choroidal-macrovascular-and-capillary-alterations-in-eyes-with-idiopathic-epiretinal-membranes
#36
JOURNAL ARTICLE
Ahmet M Hondur, Yavuz Kemal Aribas
PURPOSE: To evaluate the choroidal vascular alterations and effect of surgical treatment in the setting of idiopathic epiretinal membranes. METHODS: The structure of the choroid was studied in 33 patients with unilateral idiopathic epiretinal membrane using optical coherence tomography with enhanced depth imaging and optical coherence tomography angiography. Eyes with epiretinal membrane underwent 25-gauge vitrectomy with epiretinal membrane and internal limiting membrane peeling...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537041/primary-basal-cell-carcinoma-of-the-caruncle-case-report-and-review-of-the-literature
#37
Elizabeth Cecilia Roque-Choque, Jorge Ramiro Villalobos-Espinoza, Isabel Silva-Ocas, Rosa Alvarado-Villacorta, Pedro Muro-Mansilla
We present a rare case of primary caruncle basal cell carcinoma (BCC), a condition with limited occurrences. Our patient, an 80-year-old woman without prior ocular pathological history, presented a 2x2mm pedunculated blackish nodular lesion on the caruncle of her left eye, without local conjunctival or cutaneous involvement. Histological analysis following complete excision confirmed the presence of basal cell carcinoma within the caruncle. Over a span of 30 months, no recurrence has been observed. While scant cases are documented in the literature, we conducted a review of these instances...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537040/ligneous-conjunctivitis-fresh-frozen-plasma-and-heparin-use-intra-and-postoperatively-a-report-of-two-cases
#38
Sabela Costa Guerra Barreto de Almeida, Patrícia Maria Fernandes Marback
Ligneous conjunctivitis is a rare chronic form of recurrent membranous inflammation and plasminogen deficiency. Ocular manifestations may be associated with sites other than mucous membranes, such as the oral cavity, internal ear, respiratory, genitals, and kidney. Treatment is extremely difficult because of the lack of topic plasminogen drops, and a high volume is required for systemic supplementation. This report aimed to present two patients with ligneous conjunctivitis treated with membrane excision, topical fresh-frozen plasma, and heparin intra-, and postoperatively...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537038/novel-optical-coherence-tomography-findings-in-a-patient-with-methanol-toxicity-a-case-report
#39
Burcu Işık, Mehmet Giray Ersoz, Mehmet Dokur, Ismail Yıldız, Mehmet Sami Islamoğlu
We report a case of acute methanol toxicity with unique optical coherence tomography findings. A 56-year-old man was referred to our ophthalmology clinic with a history of handmade vodka consumption and vision loss. On ophthalmologic examination, his vision was 20/100 in his right eye and 20/200 in his left eye. Bilateral mild optic disk hyperemia was detected on fundus examination. Because of the severity of systemic symptoms in such cases, it is very difficult to include optical coherence tomography in the ophthalmologic examination...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537037/angle-closure-glaucoma-associated-with-vitreous-prolapse-after-neodymium-doped-yttrium-aluminumgarnet-laser-posterior-capsulotomy
#40
Alexis Galeno Matos, José de Paula Barbosa Neto, Carlos Philliph Pinheiro Cavalcante, Lucas Parente de Andrade, Jayter Silva Paula
Capsulotomy with neodymium-doped yttriumaluminum-garnet (Nd:YAG) laser is an effective treatment for posterior capsule opacification following cataract surgery. A wide opening of the posterior capsule associated with the ruptured anterior hyaloid can cause anterior chamber vitreous prolapse. Two patients who developed angle-closure glaucoma associated with vitreous prolapse following Nd:YAG laser posterior capsulotomy were successfully treated with antiglaucoma medication and peripheral iridotomies. Patient identification for potential risk factors and a careful postoperative follow-up are essential to avoid these serious complications...
2024: Arquivos Brasileiros de Oftalmologia
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