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Jefferson fracture

Monique Patricio Singulani, Camila Tami Stringhetta-Garcia, Leandro Figueiredo Santos, Samuel Rodrigues Lourenço Morais, Mário Jefferson Quirino Louzada, Sandra Helena Penha Oliveira, Antonio Hernandes Chaves Neto, Rita Cássia Menegati Dornelles
The effects of strength training (ST) on the mechanical bone strength and osteogenic differentiation of bone marrow mesenchymal stromal cells (BMSCs) from adult, aged and exercised aged rats were determined. The exercised aged animals displayed higher values of areal bone mineral density, compression test, alkaline phosphatase activity (ALP) and biological mineralization, while oil red O staining for adipocytes was lower. ST increased gene expression of runt-related transcription factor 2 (Runx2), osterix (Osx) as well as bone matrix protein expression, and reduced expression of peroxisome proliferator-activated receptor gamma (Pparγ)...
February 17, 2017: Scientific Reports
Fabrizio Lorenzoni E Silva, Saulo Pamato, Milton-Carlos Kuga, Marcus-Vinicius-Reis Só, Jefferson-Ricardo Pereira
BACKGROUND: To assess the immediate bond strength of a dual-cure adhesive resin cement to the hybridized dentin with different bonding systems. MATERIAL AND METHODS: Fifty-six healthy human molars were randomly divided into 7 groups (n=8). After 3 longitudinal sections, the central cuts were included in PVC matrix and were submitted to dentin hybridization according to the groups: G1 - etch & rinse system with 3-step (Apder™ Scotchbond™ Multi-Purpose, 3M ESPE), G2 - etch & rinse system with 3-step (Optibond™ FL, Kerr), G3 - etch & rinse system with 3-step (All-Bond 3®, Bisco), G4 - etch & rinse simplified system (Adper™ Single Bond 2, 3M ESPE), G5 - self-etching system with one step (Bond Force, Tokuyama), G6 - universal system in moist dentin (Single Bond Universal, 3M ESPE), G7 - universal system in dry dentin (Single Bond Universal, 3M ESPE)...
January 2017: Journal of Clinical and Experimental Dentistry
Asdrubal Falavigna, Orlando Righesso, Pedro Guarise da Silva, Carlos Rocca Siri, Jefferson W Daniel, José Carlos Esteves Veiga, Gustavo Borges Laurindo de Azevedo, Ratko Yurac, Felix Adolfo Sanchez Chavez, Ericson Sfreddo, Andre Cecchini, Marcelo Martins do Reis, K Daniel Riew
OBJECTIVE: To analyze the characteristics of type-II odontoid fractures (TII-OF); the clinical and radiographical factors that influence surgical planning in eight Latin American centers. METHODS: Retrospective chart review of 88 patients reported with TII-OF between 2004 and 2015 from eight Latin American centers. The studied parameters were: (I) demographic data, (II) cause of fracture, (III) clinical and neurologic presentation, (IV) characteristics of the fracture (degree of odontoid displacement, displacement of the odontoid relative to the C2 body, anatomy of the fracture line, the distance between fragments, presence of comminution, contact area between the odontoid and the C2 body, (V) type of treatment, (VI) clinical and radiographic outcome...
October 31, 2016: World Neurosurgery
Gregory D Schroeder, Mark F Kurd, Christopher K Kepler, James C Krieg, Jefferson R Wilson, Conor P Kleweno, Reza Firoozabadi, Carlo Bellabarba, Frank Kandizoria, Klause J Schnake, S Rajesekaran, Marcel F Dvorak, Jens R Chapman, Luiz R Vialle, F C Oner, Alexander R Vaccaro
Study Design Survey study. Objective To determine the global perspective on controversial aspects of sacral fracture classifications. Methods While developing the AOSpine Sacral Injury Classification System, a survey was sent to all members of AOSpine and AOTrauma. The survey asked four yes-or-no questions to help determine the best way to handle controversial aspects of sacral fractures in future classifications. Chi-square tests were initially used to compare surgeons' answers to the four key questions of the survey, and then the data was modeled through multivariable logistic regression analysis...
November 2016: Global Spine Journal
H H G Handoll, S D Brealey, L Jefferson, A Keding, A J Brooksbank, A J Johnstone, J J Candal-Couto, A Rangan
OBJECTIVES: Accurate characterisation of fractures is essential in fracture management trials. However, this is often hampered by poor inter-observer agreement. This article describes the practicalities of defining the fracture population, based on the Neer classification, within a pragmatic multicentre randomised controlled trial in which surgical treatment was compared with non-surgical treatment in adults with displaced fractures of the proximal humerus involving the surgical neck...
October 2016: Bone & Joint Research
Saulo Pamato, Accácio-Lins do Valle, Gustavo-Henrique-Barbosa de Andrade, Hugo-Alberto Vidotti, Marcus-Vinícius-Reis Só, Jefferson-Ricardo Pereira
BACKGROUND: Evaluate the influence of different hybridization bonding techniques of a self-adhesive resin cement. MATERIAL AND METHODS: 30 human health molars were divided into six groups (n=10). The specimens received three longitudinal sections, allowing insertion of central cuts in PVC matrices. Each group received a different dentin pretreatment according to the manufacturer's recommendations, except the control group (G1), as follows. G2 - a 3-step total-etch adhesive system (Optibond™ FL, Kerr); G3 - a 3-step total-etch adhesive system (Adper™ Scotchbond™ Multi-Purpose, 3M ESPE); G4 - a 2-step total-etch adhesive system (Adper™ Single Bond 2, 3M ESPE); G5 - a single-step self-etching system (Bond Force, Tokuyama); and G6 - universal bonding system (Single Bond Universal, 3M ESPE)...
October 2016: Journal of Clinical and Experimental Dentistry
Rafael E Arias-Berrios, Shirley A Grigg Ortiz, Natalia M Betances Ramírez, Ana M Ortiz Santiago, José A Báez
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Idiris Altun, Kasım Zafer Yuksel
STUDY DESIGN: Retrospective review. PURPOSE: We retrospectively reviewed our patients with ankylosing spondylitis (AS) to identify their patterns of spinal fractures to help clarify management strategies and the morbidity and mortality rates associated with this group of patients. OVERVIEW OF LITERATURE: Because of the brittleness of bone and long autofused spinal segments in AS, spinal fractures are common even after minor trauma and often associated with overt instability...
August 2016: Asian Spine Journal
Joseph Dias, Stephen Brealey, Surabhi Choudhary, Liz Cook, Matthew Costa, Caroline Fairhurst, Catherine Hewitt, Stephen Hodgson, Laura Jefferson, Kanagaratnam Jeyapalan, Ada Keding, Paul Leighton, Amar Rangan, Gerry Richardson, Claire Rothery, Nicholas Taub, John Thompson, David Torgerson
BACKGROUND: A scaphoid fracture is the most common type of carpal fracture affecting young active people. The optimal management of this fracture is uncertain. When treated with a cast, 88 to 90 % of these fractures unite; however, for the remaining 10-12 % the non-union almost invariably leads to arthritis. The alternative is surgery to fix the scaphoid with a screw at the outset. METHODS/DESIGN: We will conduct a randomised controlled trial (RCT) of 438 adult patients with a "clear" and "bicortical" scaphoid waist fracture on plain radiographs to evaluate the clinical effectiveness and cost-effectiveness of plaster cast treatment (with fixation of those that fail to unite) versus early surgical fixation...
June 4, 2016: BMC Musculoskeletal Disorders
Kyusik Kang, Byung Gwan Moon
BACKGROUND CONTEXT: Collet-Sicard syndrome describes the paralysis of cranial nerves IX-XII and is the most frequently reported neurologic complication associated with Jefferson fractures. As the lateral mass of the atlas is displaced laterally toward the styloid process and the stylohyoid ligament, the lateral mass impinges on cranial nerves IX-XII. However, Collet-Sicard syndrome in association with other anomalies of the atlas has rarely been reported. PURPOSE: The aim of this study was to report an unusual case of Collet-Sicard syndrome as a result of developmental abnormalities of the craniocervical junction...
September 2016: Spine Journal: Official Journal of the North American Spine Society
Frederico Carlos Jaña Neto, Marina de Paula Canal, Bernardo Aurélio Fonseca Alves, Pablício Martins Ferreira, Jefferson Castro Ayres, Robson Alves
OBJECTIVE: To analyze the characteristics of patients with Gustilo-Anderson Type III open tibial fractures treated at a tertiary care hospital in São Paulo between January 2013 and August 2014. METHODS: This was a cross-sectional retrospective study. The following data were gathered from the electronic medical records: age; gender; diagnosis; trauma mechanism; comorbidities; associated fractures; Gustilo and Anderson, Tscherne and AO classifications; treatment (initial and definitive); presence of compartment syndrome; primary and secondary amputations; MESS (Mangled Extremity Severity Score) index; mortality rate; and infection rate...
March 2016: Revista Brasileira de Ortopedia
Luis Perez-Orribo, Samuel Kalb, Laura A Snyder, Forrest Hsu, Devika Malhotra, Richard D Lefevre, Ali M Elhadi, Anna G U S Newcomb, Nicholas Theodore, Neil R Crawford
OBJECTIVE The rule of Spence is inaccurate for assessing integrity of the transverse atlantal ligament (TAL). Because CT is quick and easy to perform at most trauma centers, the authors propose a novel sequence of obtaining 2 CT scans to improve the diagnosis of TAL impairment. The sensitivity of a new CT-based method for diagnosing a TAL injury in a cadaveric model was assessed. METHODS Ten human cadaveric occipitocervical specimens were mounted horizontally in a supine posture with wooden inserts attached to the back of the skull to maintain a neutral or flexed (10°) posture...
June 2016: Journal of Neurosurgery. Spine
Rita de Cássia Alves Nunes, Fernando Yamamoto Chiba, Amanda Gomes Pereira, Renato Felipe Pereira, Maria Sara de Lima Coutinho Mattera, Edilson Ervolino, Mário Jefferson Quirino Louzada, Marília Afonso Rabelo Buzalaf, Cristina Antoniali Silva, Doris Hissako Sumida
Osteoporosis is a systemic disease characterized by bone degradation and decreased bone mass that promotes increased bone fragility and eventual fracture risk. Studies have investigated the use of sodium fluoride (NaF) for the treatment of osteoporosis. However, fluoride can alter glucose homeostasis. The aim of this study was to evaluate the effects of NaF intake (50 mg/L) from water on the following parameters of ovariectomized (OVX) rats: (1) tyrosine phosphorylation status of insulin receptor substrate (pp185 (IRS-1/IRS-2)) in white adipose tissue; (2) insulin sensitivity; (3) plasma concentrations of glucose, insulin, total cholesterol, triglyceride, TNF-α, IL-6, osteocalcin, calcium, and fluoride; (4) bone density and biomechanical properties in the tibia; and (5) tibia histomorphometric analysis...
September 2016: Biological Trace Element Research
B Corbacho, A Duarte, A Keding, H Handoll, L H Chuang, D Torgerson, S Brealey, L Jefferson, C Hewitt, A Rangan
AIMS: A pragmatic multicentre randomised controlled trial (PROFHER) was conducted in United Kingdom National Health Service (NHS) hospitals to evaluate the clinical effectiveness and cost effectiveness of surgery compared with non-surgical treatment for displaced fractures of the proximal humerus involving the surgical neck in adults. METHODS: A cost utility analysis from the NHS perspective was performed. Differences between surgical and non-surgical treatment groups in costs and quality adjusted life years (QALYs) at two years were used to derive an estimate of the cost effectiveness of surgery using regression methods...
February 2016: Bone & Joint Journal
Amanda Jefferson, Helen Leonard, Aris Siafarikas, Helen Woodhead, Sue Fyfe, Leanne M Ward, Craig Munns, Kathleen Motil, Daniel Tarquinio, Jay R Shapiro, Torkel Brismar, Bruria Ben-Zeev, Anne-Marie Bisgaard, Giangennaro Coppola, Carolyn Ellaway, Michael Freilinger, Suzanne Geerts, Peter Humphreys, Mary Jones, Jane Lane, Gunilla Larsson, Meir Lotan, Alan Percy, Mercedes Pineda, Steven Skinner, Birgit Syhler, Sue Thompson, Batia Weiss, Ingegerd Witt Engerström, Jenny Downs
OBJECTIVES: We developed clinical guidelines for the management of bone health in Rett syndrome through evidence review and the consensus of an expert panel of clinicians. METHODS: An initial guidelines draft was created which included statements based upon literature review and 11 open-ended questions where literature was lacking. The international expert panel reviewed the draft online using a 2-stage Delphi process to reach consensus agreement. Items describe the clinical assessment of bone health, bone mineral density assessment and technique, and pharmacological and non-pharmacological interventions...
2016: PloS One
Adam J Bevevino, Jin Tee, Tamir Ailon, Marcel Dvorak
No abstract text is available yet for this article.
March 2016: Clinical Spine Surgery
Camila Tami Stringhetta-Garcia, Monique Patrício Singulani, Leandro Figueiredo Santos, Mário Jefferson Quirino Louzada, Ana Cláudia Stevanato Nakamune, Antonio Hernandes Chaves-Neto, Ana Cláudia Rossi, Edilson Ervolino, Rita Cássia Menegati Dornelles
The aim of this study was to investigate the effects of strength training (ST) and raloxifene (Ral), alone or in combination, on the prevention of bone loss in an aging estrogen-deficient rat model. Aging Wistar female rats were ovariectomized at 14months and allocated to four groups: (1) non-trained and treated with vehicle, NT-Veh; (2) strength training and treated with vehicle, ST-Veh; (3) non-trained and treated with raloxifene, NT-Ral; and (4) strength training and treated with raloxifene, ST-Ral. ST was performed on a ladder three times per week and Ral was administered daily by gavage (1mg/kg/day), both for 120days...
April 2016: Bone
Abhijit Yuvaraj Pawar, Patrick F O'Leary
An 18-year-old male presented after a motor vehicle rollover accident. Computed tomography (CT) scan confirmed the diagnosis of Type II odontoid fracture. Considering the patient's young age and the limitations of C1-C2 fusion including significant loss of cervical rotation, temporary internal fixation with a lateral mass fixation of C1 and pedicle fixation of C2 without fusion was done. CT scan done at 6-month follow-up visit showed healed odontoid fracture and excellent C1-C2 alignment. At ninth postoperative month, internal fixation was removed...
December 2015: Asian Spine Journal
Andrea Barcelos, Pedro Celiny Ramos Garcia, Janete L Portela, Jefferson P Piva, João Pedro Tedesco Garcia, João Carlos B Santana
OBJECTIVE: to compare the efficacy of two analgesia protocols (ketamine versus morphine) associated with midazolam for the reduction of dislocations or closed fractures in children. METHODS: randomized clinical trial comparing morphine (0.1mg/kg; max 5mg) and ketamine (2.0mg/kg, max 70mg) associated with midazolam (0.2mg/kg; max 10mg) in the reduction of dislocations or closed fractures in children treated at the pediatrics emergency room (October 2010 and September 2011)...
August 2015: Revista da Associação Médica Brasileira
Clary Jefferson Foote, Raman Mundi, Parag Sancheti, Hitesh Gopalan, Prakash Kotwal, Vijay Shetty, Mandeep Dhillon, Philip Devereaux, Lehana Thabane, Ilyas Aleem, Rebecca Q Ivers, Mohit Bhandari
BACKGROUND: There is little data in low-income and middle-income countries (LMICs) quantifying the burden of fractures and describing current practices. The aim of the study was describe the severity of musculoskeletal injuries in LMICS and identify modifiable factors that predict subsequent early all-cause mortality. METHODS: We did a multicentre, prospective, observational study of patients who presented to 14 hospitals across India for musculoskeletal trauma (fractures or dislocations)...
April 27, 2015: Lancet
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