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https://www.readbyqxmd.com/read/28931686/host-noncoding-retrotransposons-induced-by-dna-viruses-a-sine-of-infection
#1
Jessica M Tucker, Britt A Glaunsinger
Our genomes are dominated by repetitive elements. The majority of these elements derive from retrotransposons, which expand throughout the genome through a process of reverse transcription and integration. Short interspersed nuclear elements, or SINEs, are an abundant class of retrotransposons that are transcribed by RNA polymerase III, thus generating exclusively noncoding RNA (ncRNA) that must hijack the machinery required for their transposition. SINE loci are generally transcriptionally repressed in somatic cells, but can be robustly induced upon infection with multiple DNA viruses...
September 20, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28931546/a-new-paradigm-of-sodium-regulation-in-inflammation-and-hypertension
#2
Annet Kirabo
Dysregulation of sodium (Na(+)) balance is a major cause of hypertensive cardiovascular disease. The current dogma is that interstitial Na(+) readily equilibrates with plasma and that renal excretion and reabsorption is sufficient to regulate extracellular fluid volume and control blood pressure. These ideas have been recently challenged by the discovery that Na(+) accumulates in tissues without commensurate volume retention and activates immune cells, leading to hypertension and autoimmune disease. However, objections have been raised to this new paradigm, with some investigators concerned about where and how salt is stored in tissues...
September 20, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28927286/six-year-follow-up-after-insulin-pump-initiation-hba1c-is-significantly-reduced-without-weight-gain
#3
Henrik Ullits Andersen, Sine Hangaard, Eva Hommel, Martin Ridderstråle
No abstract text is available yet for this article.
September 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28923725/petroleum-degradation-by-endophytic-streptomyces-spp-isolated-from-plants-grown-in-contaminated-soil-of-southern-algeria
#4
Hafida Baoune, Aminata Ould El Hadj-Khelil, Graciela Pucci, Pedro Sineli, Lotfi Loucif, Marta Alejandra Polti
Petroleum hydrocarbons are well known by their high toxicity and recalcitrant properties. Their increasing utilization around worldwide led to environmental contamination. Phytoremediation using plant-associated microbe is an interesting approach for petroleum degradation and actinobacteria have a great potential for that. For this purpose, our study aimed to isolate, characterize, and assess the ability of endophytic actinobacteria to degrade crude petroleum, as well as to produce plant growth promoting traits...
September 15, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28917818/assessment-of-shipping-emissions-on-four-ports-of-portugal
#5
R A O Nunes, M C M Alvim-Ferraz, F G Martins, S I V Sousa
In the last few years, ship emissions have attracted growing attention in the scientific community. The main reason is the constant increase of marine emissions over the last twenty years due to the intensification of port traffic. Thus, this study aimed to evaluate ship emissions (PM10, PM2.5, NOx, SO2, CO, CO2, N2O CH4, NMVOC, and HC) through the activity-based methodology in four of the main ports of Portugal (Leixões, Setúbal, Sines and Viana do Castelo) during 2013 and 2014. The analysis was performed according to ship types (bulk carrier, container, general cargo, passenger, Ro-Ro cargo, tanker and others) and operational modes (manoeuvring, hotelling and during cruising)...
September 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28914756/an-anti-electromagnetic-attack-puf-based-on-a-configurable-ring-oscillator-for-wireless-sensor-networks
#6
Zhaojun Lu, Dongfang Li, Hailong Liu, Mingyang Gong, Zhenglin Liu
Wireless sensor networks (WSNs) are an emerging technology employed in some crucial applications. However, limited resources and physical exposure to attackers make security a challenging issue for a WSN. Ring oscillator-based physical unclonable function (RO PUF) is a potential option to protect the security of sensor nodes because it is able to generate random responses efficiently for a key extraction mechanism, which prevents the non-volatile memory from storing secret keys. In order to deploy RO PUF in a WSN, hardware efficiency, randomness, uniqueness, and reliability should be taken into account...
September 15, 2017: Sensors
https://www.readbyqxmd.com/read/28903462/distribution-diversity-and-long-term-retention-of-grass-short-interspersed-nuclear-elements-sines
#7
Hongliang Mao, Hao Wang
Instances of highly conserved plant short interspersed nuclear element (SINE) families and their enrichment near genes have been well documented, but little is known about the general patterns of such conservation and enrichment and underlying mechanisms. Here, we perform a comprehensive investigation of the structure, distribution, and evolution of SINEs in the grass family by analyzing 14 grass and 5 other flowering plant genomes using comparative genomics methods. We identify 61 SINE families composed of 29,572 copies, in which 46 families are first described...
August 1, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/28900618/comparative-genomic-in-situ-hybridization-and-the-possible-role-of-retroelements-in-the-karyotypic-evolution-of-three-akodontini-species
#8
Naiara Pereira Araújo, Gustavo Campos Silva Kuhn, Flávia Nunes Vieira, Thaís Queiroz Morcatty, Adriano Pereira Paglia, Marta Svartman
South American Akodontini rodents are characterized by a large number of chromosome rearrangements. Among them, the genus Akodon has been extensively analyzed with classical and molecular cytogenetics, which allowed the identification of a large number of intra- and interspecific chromosomal variation due to Robertsonian rearrangements, pericentric inversions, and heterochromatin additions/deletions. In order to shed some light on the cause of these rearrangements, we comparatively analyzed the karyotypes of three Akodontini species, Akodon cursor (2n = 14, FN = 19), A...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28891195/prevalence-of-synchronous-bilateral-tonsil-squamous-cell-carcinoma-a-retrospective-study
#9
Malene Sine Rokkjaer, Tejs Ehlers Klug
OBJECTIVES: The prevalence of synchronous bilateral tonsil cancer remains unexplored. To date, only 38 cases have been described in the literature. With an aim to substantiate the Danish recommendation of performing bilateral tonsillectomy in patients with suspected or proven tonsil cancer and in patients with cervical carcinoma metastasis from an unknown primary tumour, the current study was undertaken to determine the prevalence of synchronous bilateral tonsil cancer. DESIGN: A retrospective review of all patients diagnosed with tonsil cancer in the period 2000-2015, Aarhus University Hospital, Denmark, was performed...
September 11, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28888183/periodic-population-codes-from-a-single-circular-variable-to-higher-dimensions-multiple-nested-scales-and-conceptual-spaces
#10
REVIEW
Andreas Vm Herz, Alexander Mathis, Martin Stemmler
Across the nervous system, neurons often encode circular stimuli using tuning curves that are not sine or cosine functions, but that belong to the richer class of von Mises functions, which are periodic variants of Gaussians. For a population of neurons encoding a single circular variable with such canonical tuning curves, computing a simple population vector is the optimal read-out of the most likely stimulus. We argue that the advantages of population vector read-outs are so compelling that even the neural representation of the outside world's flat Euclidean geometry is curled up into a torus (a circle times a circle), creating the hexagonal activity patterns of mammalian grid cells...
September 6, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28884931/percutaneous-ventricular-assist-devices-for-catheter-ablation-of-ventricular-tachycardia-in-structural-heart-disease-a-conditio-sine-qua-non
#11
EDITORIAL
Jorge Romero, Luigi Di Biase
No abstract text is available yet for this article.
September 8, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28883742/somatic-symptom-profiles-in-the-general-population-a-latent-class-analysis-in-a-danish-population-based-health-survey
#12
Marie Eliasen, Torben Jørgensen, Andreas Schröder, Thomas Meinertz Dantoft, Per Fink, Chalotte Heinsvig Poulsen, Nanna Borup Johansen, Lene Falgaard Eplov, Sine Skovbjerg, Svend Kreiner
PURPOSE: The aim of this study was to identify and describe somatic symptom profiles in the general adult population in order to enable further epidemiological research within multiple somatic symptoms. METHODS: Information on 19 self-reported common somatic symptoms was achieved from a population-based questionnaire survey of 36,163 randomly selected adults in the Capital Region of Denmark (55.4% women). The participants stated whether they had been considerably bothered by each symptom within 14 days prior to answering the questionnaire...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28881784/selective-inhibitors-of-nuclear-export-sine-compounds-block-proliferation-and-migration-of-triple-negative-breast-cancer-cells-by-restoring-expression-of-arrdc3
#13
Young Hwa Soung, Trinayan Kashyap, Thalia Nguyen, Garima Yadav, Hua Chang, Yosef Landesman, Jun Chung
Arrestin-related domain-containing protein-3 (ARRDC3) is one of 6 mammalian arrestins, which suppresses metastasis by inducing degradation of phosphorylated β2-adrenergic receptor (β2 AR) and integrin β4 (ITG β4). Our previous studies demonstrated that expression of ARRDC3 is epigentically silenced in Triple Negative Breast Cancer (TNBC) cells, and the forced expression of ARRDC3 significantly reduced the invasive potential of TNBC cells. In the current study, we found that Selective Inhibitors of Nuclear Export (SINE) compounds (KPT-185 and selinexor (KPT-330)) restore ARRDC3 expression in TNBC cell lines (MDA-MB-231 and MDA-MB-468) at both the mRNA and protein level in a dose and time course dependent manner...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879643/adenoid-cystic-carcinoma-of-the-oral-cavity-radiology-pathology-correlation
#14
Imran Uraizee, Nicole A Cipriani, Daniel T Ginat
Adenoid cystic carcinoma in the oral cavity is an uncommon salivary gland malignancy that has a propensity for perineural spread. A high-grade variant is evidenced by an abundance of pleomorphic cells, loss of the classic biphasic epithelial-myoepithelial growth pattern, and comedonecrosis, as well as elevated Ki-67. CT and MRI can both be useful for demonstrating the extent of invasion in oral cavity-associated adenoid cystic carcinoma, which can attain the inferior alveolar nerve for perineural spread by direct invasion through the mandible...
September 6, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28874239/-atypical-subcutaneous-presentation-of-a-basal-cell-carcinoma
#15
Sine Holst-Albrechtsen, Jacob Juel, Anne Lene H Wagenblast
Basal cell carcinoma (BCC) have many treatment options either by dermatologist, with excision or radiotherapy. A 78-year-old woman had a BCC removed surgically, and 18 years after she had a subcutaneously located tumour extirpated at the same location. The result of pathological examination was BCC located atypically in the subcutis. Iatrogenic seeding from primary excision or non-radical primary excision may explain this presentation. This is only the second report of subcutaneously located BCC.
August 28, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28872118/quantification-of-the-abundance-and-charging-levels-of-transfer-rnas-in-escherichia-coli
#16
Thomas Søndergaard Stenum, Michael A Sørensen, Sine Lo Svenningsen
Transfer RNA (tRNA) is an essential part of the translational machinery in any organism. tRNAs bind and transfer amino acids to the translating ribosome. The relative levels of different tRNAs, and the ratio of aminoacylated tRNA to total tRNA, known as the charging level, are important factors in determining the accuracy and speed of translation. Therefore, the abundance and charging levels of tRNAs are important variables to measure when studying protein synthesis, for example under various stress conditions...
August 22, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28870043/-research-of-systemic-sclerosis-sine-scleroderma
#17
G Z Zhang, H B Li
No abstract text is available yet for this article.
September 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28863653/sine-wave-gating-silicon-single-photon-detectors-for-multiphoton-entanglement-experiments
#18
Nan Zhou, Wen-Hao Jiang, Luo-Kan Chen, Yu-Qiang Fang, Zheng-Da Li, Hao Liang, Yu-Ao Chen, Jun Zhang, Jian-Wei Pan
Silicon single-photon detectors (SPDs) are the key devices for detecting single photons in the visible wavelength range. Here we present high detection efficiency silicon SPDs dedicated to the generation of multiphoton entanglement based on the technique of high-frequency sine wave gating. The silicon single-photon avalanche diode components are acquired by disassembling 6 commercial single-photon counting modules (SPCMs). Using the new quenching electronics, the average detection efficiency of SPDs is increased from 68...
August 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28860324/balancing-the-yin-and-yang-of-sine
#19
Fred G Pluthero, Walter H A Kahr
No abstract text is available yet for this article.
August 31, 2017: Blood
https://www.readbyqxmd.com/read/28858814/evaluation-of-the-perceptual-characteristics-of-a-force-induced-by-asymmetric-vibrations
#20
Takeshi Tanabe, Hiroaki Yano, Hiroo Iwata
This paper describes the properties of proprioceptive sensations induced by asymmetric vibration using a vibration speaker-type non-grounded haptic interface. We confirm that the vibration speaker generates a perceived force that pulls or pushes a user's hand in a particular direction when an asymmetric amplitude signal that is generated by inverting a part of a sine wave is input. In this paper, to verify the system with respect to various factors of force perception caused by asymmetric vibration, we conducted six experiments and the following results were obtained...
August 29, 2017: IEEE Transactions on Haptics
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