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https://www.readbyqxmd.com/read/28230461/what-is-the-essence-of-hypnosis
#1
Paul F Dell
The author explores the nature of hypnosis, which he characterizes as a motivated mode of neural functioning that enables most humans to alter, to varying degrees, their experience of body, self, actions, and world. The essence of hypnosis is not to be found in hetero-hypnosis; instead, it lies in the spontaneous self-activation of that mode of neural functioning. The hypnosis field has substantially lost sight of spontaneous self-activation, because the word hypnosis is usually used to mean hetero-hypnosis...
April 2017: International Journal of Clinical and Experimental Hypnosis
https://www.readbyqxmd.com/read/28229420/noninvasive-assessment-of-cell-fate-and-biology-in-transplanted-mesenchymal-stem-cells
#2
Federico Franchi, Martin Rodriguez-Porcel
Recently, molecular imaging has become a conditio sine qua non for cell-based regenerative medicine. Developments in molecular imaging techniques, such as reporter gene technology, have increasingly enabled the noninvasive assessment of the fate and biology of cells after cardiovascular applications. In this context, bioluminescence imaging is the most commonly used imaging modality in small animal models of preclinical studies. Here, we present a detailed protocol of a reporter gene imaging approach for monitoring the viability and biology of Mesenchymal Stem Cells transplanted in a mouse model of myocardial ischemia reperfusion injury...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28222363/very-short-term-reactive-forecasting-of-the-solar-ultraviolet-index-using-an-extreme-learning-machine-integrated-with-the-solar-zenith-angle
#3
Ravinesh C Deo, Nathan Downs, Alfio V Parisi, Jan F Adamowski, John M Quilty
Exposure to erythemally-effective solar ultraviolet radiation (UVR) that contributes to malignant keratinocyte cancers and associated health-risk is best mitigated through innovative decision-support systems, with global solar UV index (UVI) forecast necessary to inform real-time sun-protection behaviour recommendations. It follows that the UVI forecasting models are useful tools for such decision-making. In this study, a model for computationally-efficient data-driven forecasting of diffuse and global very short-term reactive (VSTR) (10-min lead-time) UVI, enhanced by drawing on the solar zenith angle (θs) data, was developed using an extreme learning machine (ELM) algorithm...
February 18, 2017: Environmental Research
https://www.readbyqxmd.com/read/28213868/elliptical-fourier-analysis-fundamentals-applications-and-value-for-forensic-anthropology
#4
REVIEW
Jodi Caple, John Byrd, Carl N Stephan
The numerical description of skeletal morphology enables forensic anthropologists to conduct objective, reproducible, and structured tests, with the added capability of verifying morphoscopic-based analyses. One technique that permits comprehensive quantification of outline shape is elliptical Fourier analysis. This curve fitting technique allows a form's outline to be approximated via the sum of multiple sine and cosine waves, permitting the profile perimeter of an object to be described in a dense (continuous) manner at a user-defined level of precision...
February 17, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28209295/aluternative-regulation-for-gene-expression
#5
REVIEW
Ling-Ling Chen, Li Yang
Alu elements belong to the primate-specific SINE family of retrotransposons and constitute almost 11% of the human genome. Alus are transcribed by RNA polymerase (Pol) III and are inserted back into the genome with the help of autonomous LINE retroelements. Since Alu elements are preferentially located near to or within gene-rich regions, they can affect gene expression by distinct mechanisms of action at both DNA and RNA levels. In this review we focus on recent advances of how Alu elements are pervasively involved in gene regulation...
February 10, 2017: Trends in Cell Biology
https://www.readbyqxmd.com/read/28208693/a-miniature-magnetic-force-based-three-axis-ac-magnetic-sensor-with-piezoelectric-vibrational-energy-harvesting-functions
#6
Chiao-Fang Hung, Po-Chen Yeh, Tien-Kan Chung
In this paper, we demonstrate a miniature magnetic-force-based, three-axis, AC magnetic sensor with piezoelectric/vibrational energy-harvesting functions. For magnetic sensing, the sensor employs a magnetic-mechanical-piezoelectric configuration (which uses magnetic force and torque, a compact, single, mechanical mechanism, and the piezoelectric effect) to convert x-axis and y-axis in-plane and z-axis magnetic fields into piezoelectric voltage outputs. Under the x-axis magnetic field (sine-wave, 100 Hz, 0.2-3...
February 8, 2017: Sensors
https://www.readbyqxmd.com/read/28202826/-hypogeusia-and-high-signals-in-the-nuclei-of-the-solitary-tract-on-mri-due-to-varicella-zoster-virus-infection-a-case-report
#7
Yuji Shiga, Yuhei Kanaya, Shinichi Takeshima, Yutaka Shimoe, Akio Tanaka, Masaru Kuriyama
A 63-year-old man noticed hypogeusia after presenting hiccups for several days. He was serologically diagnosed with varicella-zoster virus (VZV) infection, but had no skin lesions typical of herpes (zoster sine herpete). Hypogeusia was confirmed by electrogustometry and the filter-paper disk method, which showed damage in the areas innervated by the cord of tympanum, glossopharyngeal nerve, and greater petrosal nerve. High signals in the nuclei of the solitary tract of the medulla oblongata and the enhancement of the bilateral intracranial segments of the cranial nerve IX and X complex were observed by magnetic resonance imaging (MRI)...
February 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28202528/distinct-levels-of-radioresistance-in-lgr5-colonic-epithelial-stem-cells-versus-lgr5-small-intestinal-stem-cells
#8
Guoqiang Hua, Chu Wang, Yan Pan, Zhaoshi Zeng, Sang Gyu Lee, Maria Laura Martin, Adriana Haimovitz-Friedman, Zvi Fuks, Philip B Paty, Richard N Kolesnick
While small and large intestines possess seemingly similar Wnt-driven Leucine-rich repeat-containing G protein coupled receptor 5 (Lgr5)+ adult epithelial stem cells, we report here that the two organs exhibit distinct mechanisms of tissue response to ionizing radiation. Employing Lgr5-lacZ transgenic mice and Lgr5 in situ hybridization, we found colonic epithelial stem cells (CESC) markedly more radioresistant in vivo than small intestinal crypt base columnar stem cells (CBC) (D0 6.0±0.3 Gy vs. 1.3±0.1, respectively; p0...
February 15, 2017: Cancer Research
https://www.readbyqxmd.com/read/28192589/a-critical-evaluation-of-refractive-outcomes-following-lasik-for-moderate-to-high-astigmatism-using-two-excimer-laser-platforms
#9
Sudi Patel, Maja Bohac, Alma Biscevic, Mateja Koncarevic, Marija Anticic, Nikica Gabric
PURPOSE: To calculate the surgically induced astigmatism (SIA) following LASIK and identify any association between SIA and the target induced astigmatism (TIA) at 1 year postoperatively. METHODS: The SIA was calculated using the TIA and residual astigmatism values for [A] myopic astigmatism and [B] mixed astigmatism treated with either the [I] WaveLight Allegretto EyeQ 400-Hz (Alcon Laboratories, Inc. Fort Worth, TX) or [II] Schwind Amaris 750S (Schwind eye-tech-solutions, Kleinostheim, Germany) platforms...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28168515/the-bamboo-aquaporin-gene-petip4-1-1-confers-drought-and-salinity-tolerance-in-transgenic-arabidopsis
#10
Huayu Sun, Lichao Li, Yongfeng Lou, Hansheng Zhao, Yihong Yang, Sining Wang, Zhimin Gao
PeTIP4;1-1, an aquaporin gene involved in bamboo shoot growth, is regulated by abiotic stresses. Overexpression of PeTIP4;1-1 confers drought and salinity tolerance in transgenic Arabidopsis. Aquaporins play a central role in numerous physiological processes throughout plant growth and development. PeTIP4;1-1, an aquaporin gene isolated from moso bamboo (Phyllostachys edulis), comprises an open reading frame (ORF) of 756 bp encoding a peptide of 251 amino acids. The genomic sequence corresponding to the ORF of PeTIP4;1-1 was 1777 bp and contained three exons separated by two introns...
February 6, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28157843/perifoveal-s-cone-and-rod-driven-temporal-contrast-sensitivities-at-different-retinal-illuminances
#11
Cord Huchzermeyer, Jan Kremers
We evaluated a technique for measuring temporal contrast sensitivities to sine-wave modulation driven by S-cones and rods in the perifovea using triple silent substitution. Isolating stimuli for S-cones and rods were created using an eight-channel, four-primary LED stimulator that has been validated before. Sensitivities were measured at 10 different temporal frequencies between 1 and 28 Hz in three normal observers at 14 different retinal illuminances between 0.07 and 587 photopic troland (phot Td) and at three different retinal illuminances over the same range in one S-cone monochromat...
February 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/28148715/the-exportin-1-inhibitor-selinexor-exerts-superior-anti-tumor-activity-when-combined-with-t-cell-checkpoint-inhibitors
#12
Matthew R Farren, Rebecca C Hennessey, Reena Shakya, Omar Elnaggar, Gregory Young, Kari Kendra, Yosef Landesman, Sivan Elloul, Marsha Crochiere, Boris Klebanov, Trinayan Kashyap, Christin E Burd, Gregory B Lesinski
Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound targeting exportin-1, has previously been shown to inhibit melanoma cell growth in vivo. We hypothesized that combining selinexor with antibodies that block or disrupt T cell checkpoint molecule signaling would exert superior anti-melanoma activity. In vitro, selinexor increased PD-1 and CTLA4 gene expression in leukocytes and induced PD L1 gene expression in human melanoma cell lines. Mice bearing syngeneic B16F10 melanoma tumors demonstrated a significant reduction in tumor growth rate in response to the combination of selinexor and anti-PD-1 or anti-PD-L1 antibodies (p<0...
February 1, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28139954/a-need-for-dynamic-hematology-and-serum-biochemistry-reference-tools-novel-use-of-sine-wave-functions-to-produce-seasonally-varying-reference-curves-in-platypuses-ornithorhynchus-anatinus
#13
James W Macgregor, Carly S Holyoake, Joanne H Connolly, Ian D Robertson, Patricia A Fleming, Kristin S Warren
Seasonal changes in hematology and serum biochemistry results, described by separate reference intervals for different seasons, have been reported in many animals. We developed a novel method to investigate seasonal variation in values and a reference tool (the reference curve) based on sine wave functions that, for suitable variables, represents data more appropriately than a fixed reference interval. We applied these techniques to values observed in blood samples from 126 adult wild platypuses ( Ornithorhynchus anatinus ) (58 females and 68 males)...
January 31, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28134646/sine-qua-non-conditions-for-research
#14
Kun Hwang
No abstract text is available yet for this article.
January 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28133930/in-vitro-evaluation-of-selective-inhibitors-of-nuclear-export-sine-drugs-kpt-185-and-kpt-335-against-canine-mammary-carcinoma-and-transitional-cell-carcinoma-tumor-initiating-cells
#15
J E Grayton, T Miller, H Wilson-Robles
No abstract text is available yet for this article.
January 30, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28131659/sine-polymorphism-reveals-distinct-strains-of-entamoeba-histolytica-from-north-india
#16
Shraddha Sharma, Neha Banyal, Mukul Singh, A K Mandal, Sudha Bhattacharya, Jaishree Paul
Entamoeba histolytica is an intestinal parasite causing significant morbidity and mortality in the developing world. More tools are needed to understand the epidemiology and molecular pathogenesis of amebiasis. Virulence pattern of E. histolytica could be linked with the genotype of a strain. Several loci showing insertion polymorphism of retrotransposable short interspersed nuclear elements EhSINE1 and EhSINE2 have been reported among laboratory strains of E. histolytica. The present study was undertaken to validate this observation in clinical isolates from north India...
January 26, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28131381/bartonella-bovis-and-candidatus-bartonella-davousti-in-cattle-from-senegal
#17
Mustapha Dahmani, Masse Sambou, Pierre Scandola, Didier Raoult, Florence Fenollar, Oleg Mediannikov
In Senegal, domestic ruminants play a vital role in the economy and agriculture and as a food source for people. Bartonellosis in animals is a neglected disease in the tropical regions, and little information is available about the occurrence of this disease in African ruminants. Human bartonellosis due to Bartonella quintana has been previously reported in Senegal. In this study, 199 domestic ruminants, including 104 cattle, 43 sheep, and 52 goats were sampled in villages from the Senegalese regions of Sine Saloum and Casamance...
February 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/28131101/cellular-growth-in-plants-requires-regulation-of-cell-wall-biochemistry
#18
REVIEW
Youssef Chebli, Anja Geitmann
Cell and organ morphogenesis in plants are regulated by the chemical structure and mechanical properties of the extracellular matrix, the cell wall. The two primary load bearing components in the plant cell wall, the pectin matrix and the cellulose/xyloglucan network, are constantly remodelled to generate the morphological changes required during plant development. This remodelling is regulated by a plethora of loosening and stiffening agents such as pectin methyl-esterases, calcium ions, expansins, and glucanases...
January 25, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/28128811/-herpes-zoster-and-post-herpetic-neuralgia-in-the-elderly-particularities-in-prevention-diagnosis-and-treatment
#19
Ana Isabel García-González, Oscar Rosas-Carrasco
Herpes zoster (HZ) results from the reactivation of the varicella zoster virus latent in the sensory ganglia when cell-mediated immunity is altered. It is a frequent condition in older adults, leading to undesirable adverse outcomes. Aging is its main risk factor and the elderly may have different clinical presentations: zoster sine herpete, and a higher incidence of post-herpetic neuralgia (15%) and ophthalmic herpes (7%). Both HZ and post-herpetic neuralgia may impact the quality of life, functional status, mental health, and social interaction in older adults...
January 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28122478/a-no-moving-parts-sensor-for-the-detection-of-eye-fixation-using-polarised-light-and-retinal-birefringence-information
#20
Boris I Gramatikov, David L Guyton
Polarised near-infra-red light is reflected from the foveal area in a detectable bow-tie pattern of polarisation states, offering the opportunity for eye tracking. A coaxial optical transducer was developed, consisting of a laser diode, a polariser, a filter, and a photodetector. Several such transducers may be used to interrogate different spots on the retina, thus eliminating the requirement for scanning systems with moving parts. To test the signal quality obtainable, using just one transducer, a test subject was asked to fixate successively on twelve targets located on a circle around the transducer, to simulate the retina's being interrogated by twelve sensors placed on a 3(0) diameter circle surrounding the projection of the fovea...
January 26, 2017: Journal of Medical Engineering & Technology
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