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https://www.readbyqxmd.com/read/29144907/re-impact-of-body-mass-index-age-and-varicocele-on-reproductive-hormone-profile-from-elderly-men
#1
Tomas L Griebling
No abstract text is available yet for this article.
December 2017: Journal of Urology
https://www.readbyqxmd.com/read/29138814/grape-seed-proanthocyanidin-extract-attenuates-varicocele%C3%A2-induced-testicular-oxidative-injury-in-rats-by-activating-the-nrf2%C3%A2-antioxidant-system
#2
Yong Wang, Fan Chen, Ming Liang, Shouzhen Chen, Yaofeng Zhu, Zhichuan Zou, Benkang Shi
The present study investigated whether grape seed proanthocyanidin extract (GSPE) can attenuate varicocele‑induced testicular oxidative injury through the nuclear factor (erythroid‑derived 2)‑like 2 (Nrf2) antioxidant pathway. A varicocele model in rats was established by partial ligation of the left renal vein. Following 4 weeks of GSPE administration, the decreased sperm count and motility and other pathological changes caused by varicocele were significantly alleviated, as indicated by the results of computer‑assisted sperm analysis and hematoxylin and eosin staining...
November 10, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29104794/retroperitoneal-varix-ligation-with-sclerotherapy-a-prospective-randomized-comparative-study
#3
Yaser M Abdelsalam, Waleed M Saeed, Ahmed M Moeen, Ehab O Elganainy, Abdelfatah I Ahmed
Introduction: The aim of this article is to compare the results of high varix ligation with and without sclerotherapy. Material and methods: Between November 2014 and December 2015, sixty patients with varicocele were included in this study. Patients were divided into two equal groups; group I (underwent high varix ligation), and group II (underwent high varix ligation with a retrograde injection of 2 mL of 5% ethanolamine oleate in the lower end of the bisected gonadal vein)...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29093258/-treatment-of-varicocele-combined-with-asthenospermia-by-microsurgical-shunt-3-cases-report
#4
Shuang Wang, Xiongbing Zu, Longfei Liu, Juyu Tang, Xiheng Hu
To investigate the clinic value of microsurgical shunt for the treatment of varicocele combined with asthenspermia, the clinical data and therapeutic method for 3 patients, who conducted the microscope spermatic vein high ligation combined with superficial epigastric vein flow, were retrospectively analyzed. No postoperative complications were found, and the original symptoms and signs were disappeared. All patients were conducted scrotal ultrasound and semen routine after 3 months, and all indexes, including maximum internal diameter of the cord vein (erect position), sperm density, sperm survival rate, sperm deformity rate and sperm forward movement rate, were gradually improved...
October 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29089609/male-factor-infertility-varicocele-repair-in-the-era-of-assisted-reproductive-technology
#5
Mikkel Fode
No abstract text is available yet for this article.
October 31, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/29082973/sperm-dna-fragmentation-testing-in-patients-with-subclinical-varicocele-is-there-any-evidence
#6
EDITORIAL
Ahmad Majzoub, Ashok Agarwal, Sandro C Esteves
No abstract text is available yet for this article.
September 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29082207/a-strengths-weaknesses-opportunities-threats-swot-analysis-on-the-clinical-utility-of-sperm-dna-fragmentation-testing-in-specific-male-infertility-scenarios
#7
Sandro C Esteves, Ashok Agarwal, Chak-Lam Cho, Ahmad Majzoub
BACKGROUND: Sperm DNA fragmentation (SDF) is recognized as a leading cause of male infertility because it can impair the paternal genome through distinct pathophysiological mechanisms. Current evidence supports SDF as a major factor in the pathophysiology of several conditions, including varicocele, unexplained infertility, assisted reproductive technology failure, and environmental lifestyle factors, although the mechanisms involved have not been fully described yet. Measurement of the levels of DNA fragmentation in semen provides valuable information on the integrity of paternal chromatin and may guide therapeutic strategies...
September 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29082206/the-society-for-translational-medicine-clinical-practice-guidelines-for-sperm-dna-fragmentation-testing-in-male-infertility
#8
REVIEW
Ashok Agarwal, Chak-Lam Cho, Ahmad Majzoub, Sandro C Esteves
Sperm DNA fragmentation (SDF) testing has been emerging as a valuable tool for male fertility evaluation. While the essential role of sperm DNA integrity in human reproduction was extensively studied, the clinical indication of SDF testing is less clear. This clinical practice guideline provides recommendations of clinical utility of the test supported by evidence. It is intended to serve as a reference for fertility specialists in identifying the circumstances in which SDF testing should be of greatest clinical value...
September 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29071142/the-impact-of-coexisting-sperm-dna-fragmentation-and-seminal-oxidative-stress-on-the-outcome-of-varicocelectomy-in-infertile-patients-a-prospective-controlled-study
#9
Shabieb A Abdelbaki, Jehan H Sabry, Ahmed M Al-Adl, Hanan H Sabry
OBJECTIVES: To study the relationship between sperm DNA fragmentation (SDF) and reactive oxygen species (ROS) levels in infertile patients with varicocele, and to examine the beneficial effect of varicocelectomy and elucidate predictors of improvement after repair. PATIENTS SUBJECTS AND METHODS: We prospectively studied 60 patients with varicocele and abnormal semen variables who attended the outpatient clinic complaining of infertility for ≥12 months. In all, 25 patients (41...
June 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29068181/semen-parameters-in-men-with-varicocele-dna-fragmentation-chromatin-packaging-mitochondrial-membrane-potential-and-apoptosis
#10
Felipe Dieamant, Claudia G Petersen, Ana L Mauri, Vanessa Conmar, Mariana Mattila, Laura D Vagnini, Adriana Renzi, Bruna P Costa, Camila Zamara, João Batista A Oliveira, Ricardo L R Baruffi, José G Franco
OBJECTIVE: To evaluate varicocele effects on conventional semen parameters: sperm DNA fragmentation, chromatin packaging, mitochondrial membrane potential (MMP) and sperm apoptosis. METHODS: A cross-sectional study was carried out with semen samples from 2,399 men of couples who attended an infertility clinic. A total of 16.3% (391/2399) of the men were diagnosed with varicocele by a urologist. RESULTS: A regression analysis revealed that the percentages of sperm with DNA fragmentation, abnormal chromatin packaging, and abnormal MMP were significantly increased in individuals with varicocele, when compared to men without varicocele...
October 25, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29057495/impact-of-varicocelectomy-on-the-proteome-profile-of-testicular-tissues-of-rats-with-varicocele
#11
F Xu, Q Q Gao, L L Zhu, H S Jiang, H Chen, Z P Xu, Y Chen, Y T Dai
Varicocele (VC) is a common cause of male infertility, but the molecular mechanisms involved in its pathogenesis are unknown. We investigated the impact of varicocelectomy (VCT) on proteome profiles in testicular tissues of rats with VC, and analysed associated target genes and signalling pathways. Sixty male rats with VC were divided into two groups: control (n = 30), and VCT (n = 30). Tissues were collected 4 weeks after sham or VCT surgery. Matrix-assisted laser desorption/ionisation time-of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF MS) was used to analyse the comparative proteome profiles...
October 23, 2017: Andrologia
https://www.readbyqxmd.com/read/29051002/men-with-severe-oligospermia-appear-to-benefit-from-varicocele-repair-a-cost-effectiveness-analysis-of-assisted-reproductive-technology
#12
Justin M Dubin, Aubrey B Greer, Taylor P Kohn, Thomas A Masterson, Lunan Ji, Ranjith Ramasamy
OBJECTIVE: To evaluate the outcomes of men who underwent varicocelectomy for TMSC < 2 million and to perform a cost effectiveness analysis of IUI and IVF/ICSI after varicocelectomy. METHODS: We prospectively collected data of men with TMSC less than 2 million who underwent microsurgical subinguinal varicocelectomy. Men with azoospermia were excluded. Serum testosterone, luteinizing hormone, and follicle stimulating hormone were measured pre-operatively. Post-operative semen analysis was collected first at 3 months and then every 3 months thereafter...
October 16, 2017: Urology
https://www.readbyqxmd.com/read/29050000/spinal-cord-injury-following-antegrade-scrotal-sclerotherapy-for-varcicocele-a-case-report
#13
Maxime Rossi, Daniel Jacobs, Eric Wespes, Thierry Roumeguère, Pierre Raynal
Varicocele is one of the causes of male infertility. Treatment aims to improve the chance of conception despite lasting controversies about benefits of varicocele repair on fertility. Many techniques have been described for varicocele management including the antegrade scrotal sclerotherapy (ASS). Interestingly, ASS is often presented as a safe, easy, and cost-effective procedure with low recurrence and complication rates. However, we report the first case of spinal cord paralysis following ASS probably due to embolization of venous anastomoses between left spermatic and ascending lumbar veins, which were undetected at preoperative phlebography...
October 19, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29046808/occurrence-and-reproductive-roles-of-hormones-in-seminal-plasma
#14
Jana Vitku, Lucie Kolatorova, Richard Hampl
Only 2-5% of seminal fluid is composed of spermatozoa, while the rest is seminal plasma. The seminal plasma is a rich cocktail of organic and inorganic compounds including hormones, serving as a source of nutrients for sperm development and maturation, protecting them from infection and enabling them to overcome the immunological and chemical environment of the female reproductive tract. In this review, a survey of the hormones found in human seminal plasma, with particular emphasis on reproductive hormones is provided...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/29034283/endovenous-laser-ablation-of-spermatic-vein-for-the-treatment-of-varicocele
#15
Antonio Basile, Alessandro Motta, Giovanni Failla, Giuseppe Caltabiano, Marco Pizzarelli, Cecilia Gozzo, Davide Castiglione, Stefano Palmucci
INTRODUCTION: Varicocele is a relatively complex pathology of the scrotum veins', known to be one of the easiest to treat. Modern treatment involves both surgical (open, laparoscopic and microsurgery) and interventional approach (either with coils and/or sclerosant injection). Our aim is to demonstrate the feasibility and the reliability of endovenous laser ablation (EVLA) of the spermatic vein for the treatment of varicocele. MATERIALS AND METHODS: We consecutively and prospectively treated 11 patients (age range 24-45 years old, mean 31y) with left varicocele, phlebografically classified as Bahren type I and with indication for percutaneous treatment...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/29032240/natural-history-and-conservative-treatment-outcomes-for-hydroceles-a-retrospective-review-of-one-center-s-experience
#16
Tuğba Acer-Demir, Berk Yasin Ekenci, Doğancan Özer, Mehmet Ali Turanoğlu, Kadem Cem Haberal, Elif Bengisu Bilgin, Akgün Hiçsönmez
OBJECTIVES: To elucidate epidemiological data and hydrocele progression, we reviewed pediatric patients diagnosed with hydroceles in our institution retrospectively. METHODS: We reviewed data from 355 pediatric patients with hydroceles. Questionnaires regarding age at diagnosis, time of delivery, presence of hydroceles in the father and brothers, age at recovery, age at surgery, cause of hydrocele (if present), type of hydrocele, associated pathologies, treatments, and post-hydrocelectomy complications were completed by reviewing patients' medical records and interviewing their families...
October 12, 2017: Urology
https://www.readbyqxmd.com/read/29030685/combined-effects-of-varicocele-and-cell-phones-on-semen-and-hormonal-parameters
#17
Ingrid Schauer, Badereddin Mohamad Al-Ali
BACKGROUND: The objective of this study was to evaluate if there is a combined effect of varicocele and cell phone storage in trousers pockets on semen and hormonal parameters. METHODS: A retrospective analysis of 468 men attending an infertility clinic from 1993-2007 was performed. Varicoceles were determined by clinical examination and patients were questioned on cell phone usage and storage fashion. Semen samples were analyzed according to the World Health Organization (WHO) guidelines of 1999...
October 13, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29025782/olfactory-bulb-agenesis-with-normal-sexual-hormones
#18
Prayuth Tunsuriyawong, Krit Pongpirul, Tagann Chaisam, Petpring Prajuabpansri
An 18-year-old Caucasian man presented with a lack of sense of surrounding smell. The problem was first noticed when a family member discussed the smell of the food, which he had no idea what it was. The patient had normal development and sexual function, no history of trauma, surgery, chemical exposure or infection. Physical examination revealed no significant abnormalities. Smell threshold test using phenyl-ethyl-alcohol revealed bilateral anosmia. MRI showed bilateral aplastic olfactory bulbs and tracts associated with absent cortical growth of the olfactory sulci and asymmetrical gyrus rectus...
October 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29019709/laparoscopic-varicocelectomy-using-polymeric-ligating-clips-and-its-effect-on-semen-parameters-in-pediatric-population-with-symptomatic-varicocele-a-5-year-single-surgeon-experience
#19
Zenon Pogorelić, Magdalena Sopta, Miro Jukić, Ana Nevešćanin, Ivo Jurić, Dubravko Furlan
BACKGROUND: The aim of this study was to evaluate demographic and clinical characteristics of the children undergoing laparoscopic varicocelectomy by using polymeric ligating clips and to evaluate postoperative outcomes and analyze semen according to the grade of varicocele after surgery. PATIENTS AND METHODS: The case records of 120 pediatric patients who underwent laparoscopic varicocelectomy were retrospectively reviewed. The following parameters were examined: age, grade of varicocele, lateralization, diameter of spermatic veins, indications for surgery, duration and outcomes of surgery, complications, and recurrence rate...
October 11, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28992369/predictive-value-of-pre-operative-inflammation-based-prognostic-scores-neutrophil-to-lymphocyte-ratio-platelet-to-lymphocyte-ratio-and-monocyte-to-eosinophil-ratio-in-testicular-sperm-extraction-a-pilot-study
#20
C Yucel, M Z Keskin, O Cakmak, B Ergani, C Kose, O Celik, E Islamoglu, M Ucar, G Koc, Z Kozacioglu
To investigate the ability of some hematologic prognostic scores demonstrating inflammation in predicting sperm presence in testicular sperm extraction (TESE). We retrospectively investigated the medical data of 430 patients with the diagnosis of non-obstruc tive azoospermia (NOA) who had undergone TESE operation consecutively in our institution between the dates of January 2009 and February 2017. In all, 352 patients with the diagnosis of NOA, with bilaterally palpable vas deferens, who had undergone TESE for the first time, were included in the study...
October 9, 2017: Andrology
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