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Varicocele

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https://www.readbyqxmd.com/read/28911932/varicocelectomy-to-upgrade-semen-quality-to-allow-couples-to-use-less-invasive-forms-of-assisted-reproductive-technology
#1
Mary K Samplaski, Kirk C Lo, Ethan D Grober, Armand Zini, Keith A Jarvi
OBJECTIVE: To determine the magnitude of improvement in semen parameters after a varicocelectomy and the fraction that have improvements such that couples needing IVF or IUI are "upgraded" to needing less invasive assisted reproductive technology (ART). DESIGN: Retrospective review of prospectively collected data. SETTING: Academic medical centers. PATIENT(S): Men presenting for a fertility evaluation with a clinical varicocele...
September 11, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28904905/the-role-of-microsurgical-varicocelectomy-in-treating-male-infertility
#2
REVIEW
Alexander J Tatem, Robert E Brannigan
Varicoceles are the most common cause of male infertility. They afflict 15-20% of the general male population and 40% of males with primary infertility. Although multiple treatment modalities exist, including radiographic embolization and laparoscopy, open subinguinal microsurgical varicocelectomy is currently the gold standard of treatment for this condition. In this article, we discuss the role of varicocelectomy in the treatment of the modern infertile male and present a practical, safe, and reproducible technique for the microsurgical approach...
August 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28868836/comparative-expression-analysis-of-hsp70-hsp90-il-4-tnf-kitlg-and-kit-receptor-gene-between-varicocele-induced-and-non-varicocele-testes-of-dog
#3
Hossein Hassanpour, Amin Bigham Sadegh, Iraj Karimi, Heidar Heidari Khoei, Azarnoush Karimi, Parinaz Edalati Shaarbaf, Tahereh Karimi Shayan
Background: This study was designed to create an experimental varicocele model by a simple surgical procedure in dog with minimum invasion and to investigate the effect of varicocele-induced infertility on the expression of six related genes (HSP90, HSP70, IL- 4, TNF, KITLG and KIT receptor). MATERIALS AND METHODS: In this experimental study, the proximal part of the pampiniform plexus of dog testes was partially occluded without abdominal incision which was confirmed by venographic examination...
October 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28865536/varicocelectomy-before-assisted-reproductive-technology-are-outcomes-improved
#4
REVIEW
Taylor P Kohn, Jaden R Kohn, Alexander W Pastuszak
Clinical varicoceles have been associated with impaired semen parameters and male-factor infertility. Varicocele repair can improve live birth rates for men with clinical varicocele. Varicocelectomy is often combined with assisted reproductive techniques (ART) such as intrauterine insemination (IUI), in vitro fertilization (IVF), or intracytoplasmic sperm injection (ICSI). Here we review the literature examining varicocelectomy before ART to evaluate whether improved pregnancy outcomes are realized. Although insufficient evidence exists to determine if correcting a varicocele improves IUI outcomes, a clinical benefit is observed when correcting a clinical varicocele in oligospermic and nonobstructed azoospermic men before IVF/ICSI...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28865535/treatment-of-varicoceles-techniques-and-outcomes
#5
REVIEW
Dane Johnson, Jay Sandlow
Varicoceles, a dilation of veins within the pampiniform plexus, are present in ∼15% of the general male population. This paper reviews the indications for treatment of varicoceles, post-intervention outcomes following treatment, and the various techniques for treatment of varicoceles. The aim of this review is to describe and compare complications associated with each approach to varicocele treatment.
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28865534/varicoceles-prevalence-and-pathogenesis-in-adult-men
#6
REVIEW
Raul I Clavijo, Robert Carrasquillo, Ranjith Ramasamy
Varicocele, or dilation of the pampiniform venous plexus, affects up to 15% of men. However, few of these men encounter problems with fertility. This discrepancy between men with varicocele and the number of adversely affected men has led to abundant research to identify the mechanisms for formation of varicocele as well as the pathologic mechanisms by which varicoceles affect fertility potential. In this review, we discuss the prevalence of varicocele in adults, the anatomic features of varicocele, the leading theories as to how varicocele can negatively affect fertility potential, and finally, the current literature on the impact of varicocele on testosterone production...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28865533/introduction-varicoceles-a-contemporary-perspective
#7
Robert E Brannigan
In this Views and Reviews section, four groups of authors address the timely and highly relevant issue of varicoceles across the male life spectrum. Varicoceles are very prevalent among men presenting for an infertility workup. While reduction in bulk semen parameters (including sperm concentration, motility, and morphology) has long been recognized as a deficit caused by varicoceles, in recent years a number of investigators have shown that varicoceles can have broader, multi-faceted effects on male reproductive health...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28861295/evaluation-of-the-diagnostic-efficacy-of-strain-elastography-in-infertile-population-with-normal-and-abnormal-semen-parameters
#8
Faruk Küçükdurmaz, Mehmet Akif Sarıca, Özcan Emre, Murat Baykara, Betül Kızıldağ, Sefa Resim
OBJECTIVE: The aim of the present study was to investigate the diagnostic value of strain elastography (SE) of testicular tissues in infertile population. We also evaluated the correlation between SE results with semen parameters and hormone profiles of the patients. MATERIAL AND METHODS: A total of 61 patients and 122 testes were evaluated. Patients who were evaluated in an andrology outpatient clinic with the diagnosis of infertility and referred to radiology department for investigation of reproductive organs between June 2015 and January 2016 were included...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28861292/update-on-the-novel-management-and-future-paternity-situation-in-adolescents-with-varicocele
#9
REVIEW
Selahittin Çayan, Murat Bozlu, Erdem Akbay
Varicocele is a progressive disease, and the incidence of varicocele and varicocele related testicular hypotrophy increases with puberty. This review updates novel management and future paternity potential in adolescents with varicocele. Main goal of treatment of the adolescent varicoceles is preservation of fertility. Current recommendations for adolescent varicocele repair are testicular hypotrophy (>2 mL or >20%) on the affected side and/or impaired spermatogenesis in the post-pubertal period. The best treatment modality for adolescent varicocele should include elimination of the varicocele with lower complication rates...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28851509/treatment-of-varicocele-in-children-and-adolescents-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#10
REVIEW
Jennifer A Locke, Maryam Noparast, Kourosh Afshar
BACKGROUND: The prevalence of varicoceles is as high as 15% in children and adolescents. Optimal management of varicoceles has not been consolidated. Options include observation, radiological intervention, or surgical varicocelectomy. OBJECTIVE: Herein, we aim to assess the outcomes of radiological and surgical interventions for varicocele in children and adolescents evaluated by RCTs. STUDY DESIGN: The study subjects were children and adolescents up to 21 years old, diagnosed with varicocele and allocated to receive either "surgical or radiological intervention" or "no treatment"...
August 9, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28845931/-adjuvant-antioxidant-therapy-in-varicocele-infertility
#11
S I Gamidov, R I Ovchinnikov, A Yu Popova, A Yu Avakyan, G T Sukhikh
INTRODUCTION: Infertility affects an estimated 15% of couples globally. Male factor infertility accounts for about a half of infertility cases. About 40% of infertile men have varicocele. The aim of this study was to investigate the efficacy and safety of a complex of acetyl-L-carnitine, L-carnitine fumarate and alpha-lipoic acid (SpermActin-forte) (SA) for adjuvant antioxidant therapy after microsurgical varicocelectomy (MVE) in men with varicocele and assess its impact on the level of DNA fragmentation in sperm cells...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28835845/sleep-disturbances-and-semen-quality-in-an-italian-cross-sectional-study
#12
Paola Viganò, Francesca Chiaffarino, Viviana Bonzi, Andrea Salonia, Elena Ricci, Enrico Papaleo, Paola Agnese Mauri, Fabio Parazzini
INTRODUCTION: In order to obtain information about the relationship between sleep disturbances and sperm parameters, we analyzed data from a study conducted in a Italian Fertility Clinic, in men of couples seeking help for infertility. PATIENTS AND METHODS: Male partners with or without a medical history of reproductive organ diseases (cryptorchidism, varicocele, orchitis, testicular torsion) were eligible for the study. There were 382 men evaluated from May 2014 to November 2016, all of whom completed a self-administered questionnaire on general lifestyle habits...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/28834886/therapeutic-efficacy-and-safety-of-laparoscopic-surgery-versus-microsurgery-for-varicocele-of-adult-males-a-meta-analysis
#13
Xueliang Wu, Qingbo Liu, Ruiming Zhang, Wei Wang, Yong Gao
OBJECTIVES: This study aimed to systemically evaluate the efficacy and safety of laparoscopy versus microsurgery in the surgical therapy of varicocele in male adults. METHODS: Relevant literature, published between January 1995 and October 2012, were searched in Pubmed/Medline database, OVID, EMBASE, Chinese Biology Medicine disc (CBMdisc), CNKI, CEBM\CCD, and Cochrane database. The newly published papers were also manually searched. Randomized controlled trials (RCT) related to the surgical interventions of varicocele were included, and full texts were obtained...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28817895/re-sperm-concentration-and-forward-motility-are-not-correlated-with-age-in%C3%A2-adolescents-with-an-idiopathic-varicocele-and-symmetrical-testicular-volumes
#14
Douglas A Canning
No abstract text is available yet for this article.
September 2017: Journal of Urology
https://www.readbyqxmd.com/read/28807743/two-decades-of-experience-with-laparoscopic-varicocele-repair-in-children-standardizing-the-technique
#15
Ciro Esposito, Maria Escolino, Marco Castagnetti, Mariapina Cerulo, Alessandro Settimi, Giuseppe Cortese, Francesco Turrà, Marta Iannazzone, Serena Izzo, Giuseppe Servillo
BACKGROUND: Controversy still exists about the indications and the gold standard approach for varicocele treatment in pediatric population. OBJECTIVE: The authors report their 23 years of experience in laparoscopic varicocele repair in the pediatric population. STUDY DESIGN: We retrospectively evaluated the data of 345 consecutive patients who underwent laparoscopic left varicocelectomy from January 1993 to December 2015. Average patient age was 12...
July 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28803635/varicoceles-in-the-pediatric-and-adolescent-population-threat-to-future-fertility
#16
REVIEW
Deborah L Jacobson, Emilie K Johnson
Determining the effect of varicoceles on future fertility is challenging owing to multiple issues in children/adolescents, including: limitations in obtaining and interpreting semen analyses; potential for unequal differential testicular growth during puberty regardless of varicocele presence; and the potential for a lengthy interval between surgical intervention for varicocele in adolescence and attempts at paternity. This review presents a summary and evaluation of the available evidence relating to future fertility among children and adolescents with varicoceles...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28771041/obstructive-azoospermia-caused-by-low-ligation-of-varicocele-a-case-report
#17
Jun Hagiuda, Hiromichi Ishikawa, Masayuki Hagiwara, Hidaka Kono, Ken Nakagawa, Mototsugu Oya
Varicocele is commonly observed in male partners of infertile couples. The surgical ligation of varicoceles under microscopy can be safely performed by a skilled andrologist with most patients subsequently experiencing an improvement in semen quality. This is the first case in which obstructive azoospermia occurred after high inguinal varicocelectomy. The vas deferens was disrupted near the internal inguinal ring by fibrous tissue. A vasovasostomy was performed and semen parameters subsequently recovered.
October 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28767606/varicoceles-affect-semen-quality-of-infertile-men-in-southern-china-a-cross-sectional-study-of-5447-cases
#18
Yunshan Zhang, Tianzhong Ma, Zexuan Su, Mushi Ye, Huanshu Tian, Jianchang Li, Jianjun Liu
The association of varicoceles with infertility is well established, but the exact effect of varicoceles on semen quality among patients with infertility is still poorly known. The study aimed to examine the prevalence of varicoceles among Chinese men with infertility and to examine the factors associated with semen quality.This was a cross-sectional study of 5447 male patients treated for infertility at the Affiliated Hospital of Guangdong Medical University from October 2012 to December 2015. The patients were divided on the basis of the presence of varicoceles...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28766734/pressure-flow-pattern-of-varicocele-veins-and-its-correlation-with-testicular-blood-flow-and-semen-parameters
#19
K Ur Rehman, A B Qureshi, A Numan, H Zaneb, M S Yousaf, I Rabbani, H Rehman
The pressure pattern in varicocele veins of infertile patients and its correlation with semen quality and testicular blood flow was determined. Consecutive patients at andro-urology clinic of a teaching hospital undergoing microsurgical varicocelectomy were included. Their semen quality and testicular blood flow were determined. Peak systolic velocity (PSV) and resistive index (RI) of subcapsular and intraparenchymal branches of testicular artery were noted by colour Doppler ultrasonography. During surgery before ligation of varicocele veins, intravenous pressures of internal spermatic (ISV) and external spermatic (ESV) veins were determined at baseline and after Valsalva manoeuvre...
August 2, 2017: Andrologia
https://www.readbyqxmd.com/read/28740417/efficacy-and-safety-of-0-75-ropivacaine-instillation-into-subinguinal-wound-in-patients-after-bilateral-microsurgical-varicocelectomy-a-bi-center-randomized-double-blind-placebo-controlled-trial
#20
Wan Shou Cui, Yu Seob Shin, Jae Hyung You, A Ram Doo, Kiran Kumar Soni, Jong Kwan Park
OBJECTIVE: To evaluate the efficacy and safety of 0.75% ropivacaine instillation into inguinal wound in patients who have undergone bilateral microsurgical varicocelectomy. PATIENTS AND METHODS: Eighty-five men who were screened for bilateral varicoceles from March 2015 to July 2016 were randomized for the treatment. All patients underwent inguinal varicocelectomy by general anesthesia. After ligation of the internal spermatic veins from the spermatic cord, additional delivery of testis through inguinal incision site was done to ligate external spermatic veins and gubernacular veins...
2017: Journal of Pain Research
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