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Varicocele

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https://www.readbyqxmd.com/read/28647897/varicocele-and-semen-quality-a-retrospective-case-control-study-of-4230-patients-from-a-single-centre
#1
F Pallotti, D Paoli, T Carlini, A R Vestri, G Martino, A Lenzi, F Lombardo
PURPOSE: The aim of the present study is to assess impairment of spermatogenesis induced by varicocele in, to our knowledge, the largest single-centre caseload available to date. MATERIALS AND METHODS: We conducted a retrospective study on 4230 consecutive patients attending our Department for andrological outpatient assessment and preconception check-ups between 2011 and 2014. A total of 2113 patients had varicocele (Group V), while the remaining 2117 were selected as the control group (Group C)...
June 24, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28645617/featuring-asymptomatic-adolescent-varicoceles
#2
EDITORIAL
Christopher E Bayne, Diana Cardona-Grau, Michael H Hsieh
No abstract text is available yet for this article.
June 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28638941/subcutaneous-endoscopically-assisted-ligation-of-spermatic-vessels-seal-sv-using-an-epidural-spinal-needle-a-novel-technique-to-repair-adolescent-varicocele
#3
Furan Wang, Yi Chen, Junfeng Zhao, Hongji Zhong, Yan Li, Zhan Shi
We describe a novel technique of subcutaneous endoscopically assisted ligation of spermatic vessels (SEAL-SV) using a modified epidural-&-spinal needle. This technique achieves very cosmetic and minimally invasive outcomes. We have successfully performed SEAL-SV for five consecutive boys and considered it a simple, safe, and effective procedure for adolescent varicoceles.
June 21, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28627813/effect-of-the-oxidant-antioxidant-system-in-seminal-plasma-on-varicocele-and-idiopathic-infertility-in-male-humans
#4
Hayrullah Yazar, Fikret Halis, Yasemin Nasir, Derya Guzel, Mehmet Akdogan, Ahmet Gokce
BACKGROUND: The aim of this study was to investigate seminal oxidant-antioxidant activity in idiopathic and varicocele infertility in men. METHODS: Total anti-oxidant capacity (TAC), total oxidant status (TOS), paraoxonase (PON1), aryl esterase (ARE), and total thiol levels (TTL) were measured in seminal plasma with an autoanalyzer. The TOS/TAC ratio was determined as the oxidative stress index (OSI). A histopathological evaluation of the sperm was performed in the andrology laboratory of the hospital...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28618703/re-barriers-to-use-of-semen-analysis-in-the-adolescent-with-a-varicocele-survey-of-patient-parental-and-practitioner-attitudes
#5
Douglas A Canning
No abstract text is available yet for this article.
July 2017: Journal of Urology
https://www.readbyqxmd.com/read/28614535/should-azoospermic-patients-with-varicocele-disease-undergo-surgery-to-recover-fertility
#6
Leonardo de Souza Alves, Francisco Batista de Oliveira
Introduction: Varicocele disease is well-known cause of infertility in men. The presence of spermatic varices veins create a hostile environment to spermatogenesis. It results in reduced quality of the sperm production and in some cases can determine a total absence of sperm. The varicocelectomy procedure in patients with non-obstructive azoospermia (NOA) can raise the rates of sperm in the semen analysis. A positive rate for sperm, even if very low, may be sufficient to enable the capture of sperm intended for in-vitro fertilization without the use of donor sperm...
April 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28603623/subinguinal-microsurgical-varicocelectomy-vs-percutaneous-embolization-in-infertile-men-prospective-comparison-of-reproductive-and-functional-outcomes
#7
Elie Bou Nasr, Mouath Binhazzaa, Thierry Almont, Pascal Rischmann, Michel Soulie, Eric Huyghe
BACKGROUND: Varicocele is a condition characterized by dilated, tortuous veins within the pampiniform venous plexus of the scrotal sac. Presence of varicocele is associated with an increased risk of alteration of semen parameters. The objective of this study was to compare the current standard in varicocele treatment procedures: sub-inguinal microscopic ligation to percutaneous embolization in terms of semen parameters improvement, fertility, and morbidity at the university hospital of Toulouse (France)...
2017: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/28593638/thrombotic-and-nonthrombotic-types-of-intratesticular-varicoceles-value-of-sonography-for-the-diagnosis
#8
Emre Ünal
An intratesticular varicocele is an uncommon entity, and its clinical importance remains unclear. The diagnosis can be made in the case of an intratesticular tortuous vein that shows retrograde flow on color Doppler sonography. The anatomic location and course of the intratesticular varicocele within the testicular parenchyma and its association with the existence of an ipsilateral extratesticular varicocele may vary among patients. The pathophysiologic mechanisms remain unclear; however, it may be questioned whether there is an association between testicular atrophy and intratesticular varicocele development...
June 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28586606/varicocele-embolization-following-failure-of-varicocelectomy-a-case-series-and-review-of-literature
#9
Zain Badar, Michael Rachun, Zerwa Farooq, Megan Calabrese, Anthony Mohamed, Mohammed Jawed
Varicocelectomy remains the same mainstay of treatment for varicoceles. However, with growing focus on minimally invasive techniques, recent literature has investigated the use of venous embolization for the treatment of varicoceles in patients with recurrence after surgical treatment. Embolization has many advantages, including use of local anaesthesia, lower operating time, decreased risk of hydrocele and faster recovery times. In addition to this direct visualization of the vasculature during embolization allows for identification of any anatomic variants or collateral vessel accounting for the recurrence...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28575284/role-of-heat-shock-factor-1-in-conserving-cholesterol-transportation-in-leydig-cell-steroidogenesis-via-steroidogenic-acute-regulatory-protein
#10
Shintaro Oka, Koji Shiraishi, Mitsuaki Fujimoto, Arpit Katiyar, Ryosuke Takii, Akira Nakai, Hideyasu Matsuyama
Testicular testosterone synthesis begins with cholesterol transport into mitochondria via steroidogenic acute regulatory protein (StAR) in Leydig cells. Acute heat stress is known to obstruct testicular steroidogenesis by transcriptional repression of StAR. In contrast, chronic heat stress such as cryptorchidism or varicocele generally does not affect testicular steroidogenesis, suggesting that Leydig cells adapt to heat stress and retain their steroid synthesis ability. However, the mechanisms of the stress response in steroid-producing cells are unclear...
May 29, 2017: Endocrinology
https://www.readbyqxmd.com/read/28559777/microsurgical-subinguinal-varicocele-repair-of-grade-ii-iii-lesions-associated-with-improvements-of-testosterone-levels
#11
Saad Elzanaty, Claus Johansen
INTRODUCTION: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. MATERIALS AND METHODS: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormonal profiles available in the clinical records were reviewed. Follow-up evaluation was done at 1 and 12 months after surgery...
April 2017: Current Urology
https://www.readbyqxmd.com/read/28547739/determination-of-spermatic-vein-reflux-after-varicocele-repair-helps-to-define-the-efficacy-of-treatment-in-improving-sperm-parameters-of-subfertile-men
#12
S D'Andrea, A Micillo, A Barbonetti, A V Giordano, S Carducci, A Mancini, S Necozione, F Francavilla, S Francavilla
PURPOSE: A continuous spermatic venous reflux (SVR) at colour Doppler ultrasound (CDU) is an evidence for varicocele, a frequent correlate for male subfertility. We explored whether SVR after left varicocele repair is predictive for changes in semen quality in subfertile men. METHODS: Blood hormones (FSH, LH, and total testosterone) and scrotal CDU were obtained in subfertile patients with left grade II or grade III varicocele on physical evaluation and a poor sperm quality...
May 25, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28540245/can-we-reliably-predict-sperm-recovery-in-semen-of-nonobstructive-azoospermia-men-after-varicocele-repair-answers-are-awaited
#13
EDITORIAL
Taha Abo-Almagd Abdel-Meguid
No abstract text is available yet for this article.
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28540234/does-the-number-of-veins-ligated-during-microsurgical-subinguinal-varicocelectomy-impact-improvement-in-pain-post-surgery
#14
Haitham Elbardisi, Ashok Agarwal, Ahmad Majzoub, Sami Al Said, Hossameldin Alnawasra, Kareim Khalafalla, Khalid Al Rumaihi, Abdulla Al Ansari, Damayanthi Durairaganayagam, Mohamed Arafa
BACKGROUND: We examined the impact of the number of veins ligated during varicocelectomy on post-surgical improvement of pain in a group of men presenting with clinical varicocele and pain as an indication for surgery. METHODS: This is a retrospective study of patients presenting with clinical left varicocele to the male infertility unit at a teaching hospital in Qatar. Files of all patients who underwent sub-inguinal microsurgical varicocelectomy were retrieved and categorized into three groups indicating the number of spermatic veins ligated during varicocelectomy...
April 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28523408/genetics-and-epigenetics-of-varicocele-pathophysiology-an-overview
#15
REVIEW
Viviane Paiva Santana, Cristiana Libardi Miranda-Furtado, Flavia Gaona de Oliveira-Gennaro, Rosana Maria Dos Reis
Varicocele is found in approximately 20% of adults and adolescents and in 19-41% of men seeking treatment for infertility. It is associated with a decrease in sperm count as well as sperm motility and morphology. The currently accepted description of the pathophysiology of varicocele does not explain all its clinical manifestations; therefore, other factors such as genetic and epigenetic changes, associated with the environment, might be involved in causing infertility and decrease in sperm quality. It has been reported that the varicocele-induced deterioration of testicular function is progressive and interferes with fertility; hence, early and efficient assessment of the genetic manifestations in patients would be important for developing future medical interventions...
May 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28481072/-evaluation-of-testicular-growth-after-varicocele-treatment-in-early-childhood-and-adolescence-based-on-the-technique-used-palomo-ivanissevich-and-embolization
#16
V F Calderón Plazarte, J M Angulo Madero, C Soto Beauregard, N Pérez Romero, L F Ávila Ramírez, J Rodríguez-Alarcón García, J Moreno Sierra
OBJECTIVES: To analyze, depending on the technique employed, recurrence, symptomatic improvement and testicular growth following treatment of testicular varicocele. MATERIAL AND METHODS: Descriptive retrospective study of 69 pediatric and adolescent males diagnosed with varicocele treated in our center by open technique according Ivanissevich technique (IT), Palomo (PT) and percutaneous embolization (PE) between 2000-2014. Variables analyzed were age, symptoms, differential testicular volume (RV), employed technique, recurrence, symptomatic improvement and RV after treatment...
October 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28457832/indocyanine-green-icg-angiography-assisted-laparo-endoscopic-single-site-less-varicocelectomy
#17
Keiji Tomita, Susumu Kageyama, Eiki Hanada, Tetsuya Yoshida, Yuki Okinaka, Shigehisa Kubota, Masayuki Nagasawa, Kazuyoshi Johnin, Mitsuhiro Narita, Akihiro Kawauchi
OBJECTIVE: To study the efficacy of a new laparoscopic varicocelectomy technique using indocyanine green (ICG) angiography. METHODS: Laparo-endoscopic single-site (LESS) varicocelectomy using ICG angiography was performed in a single institution on 11 patients with a grade 2 or 3 varicocele. Adult men (N=9, 82%) who were apparently infertile and had a varicocele, as well as prepubertal males (N=2, 18%) with testicular growth retardation, underwent a LESS varicocelectomy using ICG angiography...
April 27, 2017: Urology
https://www.readbyqxmd.com/read/28456539/role-of-preoperative-testicular-shear-wave-elastography-in-predicting-improvement-of-semen-parameters-after-varicocelectomy-for-male-patients-with-primary-infertility
#18
Khaled Abdelwahab, Ahmed M Eliwa, Mohammed M Seleem, Hazem El Galaly, Ahmed Ragab, Esam A Desoky, Mohamed Naguib, Maged M Ali, Sameh Saber, Hussain Kamel
OBJECTIVES: To evaluate the role of preoperative testicular Shear wave elastography in prediction of improvement of semen analysis parameters after subinguinal microsurgical varicocele ligation in patients with primary infertility and clinically detectable varicocele. PATIENTS AND METHODS: Testicular Shear wave elastography (SWE) before the surgical intervention was done. Forty eight patients were scheduled for subinguinal microsurgical varicocele ligation as treatment option...
April 26, 2017: Urology
https://www.readbyqxmd.com/read/28441854/-correlation-between-anatomical-factors-of-spermatic-vessels-and-varicocele
#19
L Y Zhao, R H Tian, Y H Huang, H X Chen, P Li, Z Wan, C C Yao, C Yang, E L Zhi, Z Li
Objective: To analyze the correlation between anatomy of spermatic vessels and varicocele, providing reference for the preoperative assessment and treatment of varicocele. Methods: A total of 156 patients who underwent microsurgical left subinguinal varicocelectomy at Shanghai General Hospital between May 2015 and July 2016 were included in this study. The severity of varicocele and number of spermatic vessels detected in operations were recorded. According to the number of internal spermatic arteries (ISAs), the patients were divided into three groups: single-ISA group (55 cases), double-ISAs group (63 cases) and multi-ISAs group (38 cases), to analyze the correlation among spermatic vessels and to compare varicocele grade, the volume of testes, the parameter of semen analysis, serum reproductive hormone, surgery time, and hospital stay among the three groups...
April 25, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28439698/synergistic-effects-of-cigarette-smoking-and-varicocele-on-semen-parameters-in-715-patients
#20
Badereddin Mohamad Al-Ali, Klaus Eredics
OBJECTIVE: To evaluate whether there is a synergistic effect of varicocele and smoking status on semen parameters. METHODS: A retrospective evaluation of 715 men attending an infertility clinic between 2001 and 2009 was carried out. The presence of a varicocele was determined by clinical examination and cigarette smoking habits were documented allowing patients to be divided into 4 groups: non-smokers (n = 369), mild smokers (n = 186, 1-10 cigarettes/day), moderate smokers (n = 129, 10-20 cigarettes/day) and heavy smokers (n = 31, over 20 cigarettes/day)...
April 24, 2017: Wiener Klinische Wochenschrift
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