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https://www.readbyqxmd.com/read/29778600/microendoscopy-assisted-minimally-invasive-versus-open-transforaminal-lumbar-interbody-fusion-for-lumbar-degenerative-diseases-five-year-outcomes
#1
Yang Yang, Zhong-Yu Liu, Liang-Ming Zhang, Mao Pang, Kishor Chhantyal, Wen-Bin Wu, Zi-Hao Chen, Chun-Xiao Luo, Li-Min Rong, Bin Liu, Yang Yang, Zhong-Yu Liu
OBJECTIVE: To evaluate five-year outcomes between microendoscopy-assisted minimally invasive (MIS) and open transforaminal lumbar interbody fusion (TLIF). METHODS: Sixty single-level MIS and open surgeries were performed (30 patients in either group). Perioperative parameters, including operative duration, intraoperative estimated blood loss (EBL) and fluoroscopy time, postoperative analgesic usage and ambulatory time, as well as complications, were recorded. Visual analogue scale (VAS, back and leg), Japanese Orthopaedics Association score (JOA) and Oswestry disability index (ODI) were obtained...
May 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29772864/-analysis-of-delayed-infection-of-proximal-junctional-zone-after-posterior-spinal-internal-fixation-and-its-treatment-strategy
#2
Gong-Qun Jiang, Yong-Heng Liu, De-Yuan Chen, Yong-Ai Liu
OBJECTIVE: To explore the features and treatment strategy of delayed infection of proximal junctional zone after posterior spinal internal fixation. METHODS: The clinical data of 1325 patients underwent posterior spinal internal fixation were retrospectively analyzed. Delayed infection occurred in 10 patients, among which 4 infections occurred at the proximal junction (non-operative site). And these 4 patients were treated with combined broad-spectrum antibiotics...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29772861/-analysis-of-clinical-effects-in-the-treatment-of-single-segment-lumbar-degenerative-disease-by-lamina-osteotomy-and-former-vertebral-plates-regraft
#3
Da-Peng Duan, Zhi-Long Chen, Hong-Hai Xu, Zong-Zhi Liu
OBJECTIVE: To compare the clinical effect between the lamina osteotomy and former vertebral plates regraft method and total laminectomy and interbody fusion method in treating single-segment lumbar degenerative disease. METHODS: The clinical data of 167 patients with single-segment lumbar degenerative disease underwent surgical treatment from January 2010 to December 2014 were retrospectively analyzed. There were 92 males and 75 females, aged from 45 to 75 years old with an average of (59...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29772854/-observation-of-early-clinical-effect-of-percutaneous-transforaminal-endoscopic-technology-in-treating-cervical-spondylotic-radiculopathy
#4
Ying-Chun Zhang, Tai-Sheng Chen, Hua Zhu
OBJECTIVE: To explore the early clinical effect and safety of percutaneous transforaminal endoscopic technology for cervical spondylotic radiculopathy. METHODS: From August 2016 to September 2017, 14 patients with cervical spondylotic radiculopathy who responded poorly to non-surgical treatment for at least 6 weeks underwent percutaneous transforaminal endoscopic discectomy via posterior approach. There were 6 males and 8 females, aging from 32 to 68 years old with an average of (40...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29772047/swept-source-oct-angiography-identifies-choroidal-neovascularization-arising-from-a-choroidal-nevus
#5
Abed Namavari, Fang Zheng, Elie H Motulsky, João R de Oliveira Dias, Giovanni Gregori, Philip J Rosenfeld
Swept-source optical coherence tomography angiography (SS-OCTA) was used to diagnose choroidal neovascularization (CNV) arising from a choroidal nevus. A 61-year-old woman initially presented with submacular hemorrhage. She was diagnosed with neovascular age-related macular degeneration (AMD) and received three injections of bevacizumab (Avastin; Genentech, South San Francisco, CA). At a follow-up visit, SS-OCTA showed that the CNV appeared to arise from an adjacent choroidal nevus. This is the first report of using SS-OCTA to diagnose CNV associated with a choroidal nevus masquerading as neovascular AMD...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29770581/effect-of-static-compression-loads-on-intervertebral-disc-an-in-vivo-bent-rat-tail-model
#6
Wei Xia, Lin-Lin Zhang, Jun Mo, Wen Zhang, Hai-Tao Li, Zong-Ping Luo, Hui-Lin Yang
OBJECTIVE: To evaluate how well different magnitudes of compression-induced degenerative changes using a bent rat tail model simulated human lumbar lordosis. It has been shown that compression plays an important role in intervertebral disc degeneration (IDD). METHODS: Sprague-Dawley rats (n = 25) were instrumented with a special compressive apparatus that was used to bend the intervertebral disc between the 8th and the 10th caudal vertebral bodies using two Kirschner wires inserted percutaneously into the middle of two tail vertebrae...
May 16, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29770178/dynamic-stabilization-for-degenerative-diseases-in-the-lumbar-spine-2-years-results
#7
Ahmed Hosny Khalifa, Timo Stübig, Oliver Meier, Christian Walter Müller
Following lumbar fusion, adjacent segment degeneration has been frequently reported. Dynamic systems are believed to reduce main fusion drawbacks. We conducted a retrospective study on patients with degenerative lumbar disease treated with posterior dynamic stabilization with monoaxial hinged pedicular screws and lumbar decompression. VAS and ODI were used to compare clinical outcomes. As radiological outcomes, LL and SVA were used. 51 patients were included with an average follow-up of 24 months. 13 patients were revised because of postoperative radiculopathy (n=4), subcutaneous hematoma (n=2), L5 screw malposition (n=1) and adjacent segment disease (n=6)...
March 29, 2018: Orthopedic Reviews
https://www.readbyqxmd.com/read/29742622/fluorescence-in-situ-hybridization-method-reveals-that-carboxyl-terminal-fragments-of-transactive-response-dna-binding-protein-43-truncated-at-the-amino-acid-residue-218-reduce-poly-a-rna-expression
#8
Shinji Higashi, Ryohei Watanabe, Tetsuaki Arai
Transactive response (TAR) DNA-binding protein 43 (TDP-43) has emerged as an important contributor to amyotrophic lateral sclerosis and frontotemporal lobar degeneration. To understand the association of TDP-43 with complex RNA processing in disease pathogenesis, we performed fluorescence in-situ hybridization using HeLa cells transfected with a series of deleted TDP-43 constructs and investigated the effect of truncation of TDP-43 on the expression of poly(A) RNA. Endogenous and overexpressed full-length TDP-43 localized to the perichromatin region and interchromatin space adjacent to poly(A) RNA...
May 8, 2018: Neuroreport
https://www.readbyqxmd.com/read/29734212/time-course-of-radiologic-changes-after-lumbar-total-disc-replacement-experience-of-single-institute-with-minimum-5-year-follow-up
#9
Jung-Woo Hur, Jin-Sung Kim, Kyeong-Sik Ryu, Myeong-Hoon Shin, Chun-Kun Park
STUDY DESIGN: This was a retrospective observatory analysis study. OBJECTIVE: The purpose of this study was to evaluate long-term safety and therapeutic effectiveness of the lumbar total disc replacement (TDR) using ProDisc-L by analyzing the radiologic changes at the index and adjacent levels in minimum 5-year follow-up. SUMMARY OF BACKGROUND DATA: Early successful clinical results of lumbar TDR have been reported. However, few reports have published its therapeutic effectiveness and radiologic degenerative changes at the index and adjacent segments in the long term...
May 4, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29734112/a-comparison-of-a-self-locking-stand-alone-cage-and-anterior-cervical-plate-for-acdf-minimum-3-year-assessment-of-radiographic-and-clinical-outcomes
#10
Jian Zhou, Juan Li, Hong Lin, Xilei Li, Xiaogang Zhou, Jian Dong
OBJECTIVES: The self-locking stand-alone cage has been clinically applied in treating cervical degenerative disc disease (CDDD). However, no long-term clinical and radiographic studies have been performed so far. This retrospective study was designed to analyze and compare the efficacy and outcomes of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone cages and cages with the anterior cervical plating system. PATIENTS AND METHODS: A total of 98 consecutive patients were recruited in this study...
April 30, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29729460/stand-alone-anterolateral-interbody-fusion-versus-extended-posterior-fusion-for-symptomatic-adjacent-segment-degeneration-a-retrospective-study-of-2-years-follow-up
#11
Zhiming Tu, Lei Li, Bing Wang, Yawei Li, Guohua Lv, Yuliang Dai
OBJECTIVE: To evaluate the clinical and radiological outcome of stand-alone anterolateral lumbar interbody fusion (ALLIF) using self-locked cages in comparison with extended posterior lumbar interbody fusion (PLIF) for symptomatic adjacent-segment degeneration (ASD) following posterior lumbar fusion. METHODS: This retrospective study enrolled 40 symptomatic ASD patients who were treated with ALLIF (n=13) or extended PLIF (n=27) between January 2011 and January 2015...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29727498/frequency-dependent-shear-properties-of-annulus-fibrosus-and-nucleus-pulposus-by-magnetic-resonance-elastography
#12
P F Beauchemin, P V Bayly, J R Garbow, J L S Schmidt, R J Okamoto, F Chériet, D Périé
Aging and degeneration are associated with changes in mechanical properties in the intervertebral disc, generating interest in the establishment of mechanical properties as early biomarkers for the degenerative cascade. Magnetic resonance elastography (MRE) of the intervertebral disc is usually limited to the nucleus pulposus, as the annulus fibrosus is stiffer and less hydrated. The objective of this work was to adapt high-frequency needle MRE to the characterization of the shear modulus of both the nucleus pulposus and annulus fibrosus...
May 4, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29713407/the-incidence-of-adjacent-segment-degeneration-after-the-use-of-a-versatile-dynamic-hybrid-stabilization-device-in-lumbar-stenosis-results-of-a-5-8-year-follow-up
#13
Mauro Dobran, Davide Nasi, Domenico Paolo Esposito, Maurizio Gladi, Massimo Scerrati, Maurizio Iacoangeli
Study Design: Retrospective study with long-term follow-up. Purpose: To evaluate the long-term incidence of adjacent segment degeneration (ASD) and clinical outcomes in a consecutive series of patients who underwent spinal decompression associated with dynamic or hybrid stabilization with a Flex+TM stabilization system (SpineVision, Antony, France) for lumbar spinal stenosis. Overview of Literature: The incidence of ASD and clinical outcomes following dynamic or hybrid stabilization with the Flex+TM system used for lumbar spinal stenosis have not been well investigated...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29707374/successful-surgical-treatment-of-massive-spontaneous-hemothorax-due-to-intrathoracic-secondary-degeneration-of-a-neurofibroma-from-mediastinal-involvement-of-type-1-neurofibromatosis
#14
Seong Cheol Jeong, Jae Jun Kim, Si Young Choi, Yong Hwan Kim, In Sub Kim
Massive hemothorax caused by a mediastinal mass is extremely rare. Herein, we present a case of successful surgery for a massive hemothorax caused by intrathoracic cystic hemorrhagic degeneration of a neurofibroma in a patient with neurofibromatosis type 1 (NF1). A 44-year-old man with NF1 was admitted to our emergency department for chest pain and dyspnea. Image studies revealed a massive hemothorax caused by a posterior mediastinal mass adjacent to the descending aorta and the spinal canal. The tumor, located at the fourth to the sixth thoracic vertebra, had diffusely and extensively infiltrated around proliferative vessels...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29706603/impact-of-drusen-and-drusenoid-retinal-pigment-epithelium-elevation-size-and-structure-on-the-integrity-of-the-retinal-pigment-epithelium-layer
#15
Schlanitz Ferdinand, Bernhard Baumann, Stefan Sacu, Lukas Baumann, Michael Pircher, Christoph K Hitzenberger, Ursula Margarethe Schmidt-Erfurth
PURPOSE: To evaluate the impact of drusen size and structure on retinal pigment epithelium (RPE) and photoreceptor layers in eyes with early to intermediate age-related macular degeneration (AMD) using polarisation-sensitive optical coherence tomography (OCT). DESIGN: Retrospective investigation of an observational cross-sectional study. PARTICIPANTS: Patients with early to intermediate AMD. METHODS: Twenty-five eyes of 25 patients with drusen were imaged with polarisation-sensitive OCT using macular volume scans...
April 29, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29702308/unilateral-veral-pedicle-screw-fixation-combined-with-transforaminal-lumbar-interbody-fusion-rsus-bilatefor-the-treatment-of-low-lumbar-degenerative-disc-diseases-analysis-of-clinical-and-radiographic-results
#16
De-Jian Chen, Cong Yao, Quanwei Song, Benyu Tang, Xuqiang Liu, Bin Zhang, Min Dai, Tao Nie, Zongmiao Wan
OBJECTIVE: Our objective was to compare the clinical and radiographic results of unilateral pedicle screw fixation (UPSF) and bilateral pedicle screw fixation (BPSF) after unilateral transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degenerative disc diseases (DDD). MATERIALS AND METHODS: 63 patients who underwent UPSF or BPSF combined with unilateral TLIF at L4-L5 or L5-S1 were included in our hospital from 2014-2016. The perioperative outcomes and radiographic results were recorded at preoperative and postoperative follow-up...
April 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29701254/photoreceptor-cells-as-a-source-of-fundus-autofluorescence-in-recessive-stargardt-disease
#17
Maarjaliis Paavo, Winston Lee, Rando Allikmets, Stephen Tsang, Janet R Sparrow
Bisretinoid fluorophores form in photoreceptor outer segments from nonenzymatic reactions of vitamin A aldehyde. The short-wavelength autofluorescence (SW-AF) of fundus flecks in recessive Stargardt disease (STGD1) suggests a connection to these fluorophores. Through multimodal imaging, we sought to elucidate this link. Flecks observed in SW-AF images often colocalized with foci exhibiting reduced or absent near-infrared autofluorescence signal, the source of which is melanin in retinal pigment epithelial (RPE) cells...
April 27, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29693011/superior-facet-joint-violations-during-single-level-minimally-invasive-transforaminal-lumbar-interbody-fusion-a-preliminary-retrospective-clinical-study
#18
Long Jia, Yan Yu, Kamran Khan, Fuping Li, Rui Zhu, Zhili Zeng, Liming Cheng
Background: Facet joint violation (FV) was reported as variable iatrogenic damage that can be a crucial risk factor leading to the adjacent segment degeneration (ASD). "Blind" screw placement technique in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) contributes to the increasing incidence of FV that can be influenced by several potential factors. Many controversies about these factors and clinical outcomes of different types of FV patients exist, yet they have not been analyzed...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682329/active-discopathy-a-clinical-reality
#19
REVIEW
Margaux Boisson, Marie-Martine Lefèvre-Colau, François Rannou, Christelle Nguyen
In the late 1980s, the description by Modic and colleagues of elementary discovertebral changes detected on MRI (Modic classification) suggested for the first time a possible correlation between anatomical and clinical features in a subgroup of patients with non-specific chronic low back pain. Degenerative disc disease is frequent and usually asymptomatic, but Modic 1 changes in the vertebral endplates adjacent to a degenerated disc are associated with inflammatory-like chronic low back pain and low-grade local and systemic inflammation, which led to the concept of 'active discopathy'...
2018: RMD Open
https://www.readbyqxmd.com/read/29681021/clinical-and-radiological-outcomes-of-cervical-disc-arthroplasty-ten-year-follow-up-study
#20
Qingpeng Song, Da He, Xiao Han, Ning Zhang, Jinchao Wang, Wei Tian
PURPOSE: Previous studies have demonstrated that cervical disc arthroplasty has favourable short- and medium-term clinical and radiological outcomes. However, long-term follow-up outcomes have rarely been reported. The purpose of this study was to evaluate the ten year follow-up clinical and radiological outcomes in patients who underwent Bryan cervical disc arthroplasty. METHODS: Seventy-one patients who underwent single-level Bryan cervical disc arthroplasty with a minimum ten year follow-up were included in the study...
April 21, 2018: International Orthopaedics
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