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https://www.readbyqxmd.com/read/27916038/-mid-to-long-term-outcomes-of-cervical-disc-arthroplasty-for-symptomatic-cervical-disc-disease-a-meta-analysis
#1
S L Kan, B Yang, G Z Ning, S J Gao, J C Sun, S Q Feng
Objective: To compare the benefits and harms of cervical disc arthroplasty (CDA) with anterior cervical discectomy and fusion(ACDF) for symptomatic cervical disc disease at mid- to long-term follow-up. Methods: Electronic searches were made in PubMed, EMBASE, and the Cochrane Library for randomized controlled trials with at least 48 moths follow-up.Outcomes were reported as relative risk or standardized mean difference.Meta-analysis was carried out using Revman version 5.3 and Stata version 12.0. Results: Seven trials were included, involving 2 302 participants...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27916034/-the-mid-to-long-term-effect-of-wallis-lumbar-interspinous-dynamic-stabilization-on-the-adjacent-segment-degeneration
#2
X Yuan, C Kong, X M Chen, L B Cui, S J Xu, Y D Liu
Objective: To explore the mid- to long-term effect of Wallis interspinous dynamic stabilization system on the adjacent segment degeneration. Methods: From March 2009 to June 2010, in Department of Orthopedics, Beijing Luhe Hospital, Capital Medical University, 24 patients with L4-5 monosegmental lumbar disc herniation were treated with posterior lumbar decompression combined with Wallis interspinous dynamic fixation. Clinical outcomes were evaluated with visual analogue score (VAS) (back pain), VAS (leg pain) and oswestry disability index (ODI) score...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27909655/adjacent-disc-height-reduction-and-clinical-outcome-after-intradiscal-cement-leakage
#3
Minjie Shen, Junjie Niu, Haifei Zhou, Qian Meng, Minfeng Gan, Huilin Yang
OBJECTIVE: The purpose of this study is to evaluate the effect of intradiscal cement leakage on the height of adjacent cement-containing discs and the resulting clinical efficacy after kyphoplasty. METHODS: A total of 124 patients were included and classified into two groups: group A included 20 patients with intradiscal leakage, and group B contained 104 patients without intradiscal leakage. The mean follow-up time was 20.56±3.51 months. The height of the corresponding discs in both groups was measured using Farfan's method...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27876503/cranio-caudal-asymmetries-in-trabecular-architecture-reflect-vertebral-fracture-patterns
#4
Ge Yang, Michele C Battié, Steven K Boyd, Tapio Videman, Yue Wang
Clinically, vertebral fractures often occur in the upper lumbar spine and involve the superior endplate of a vertebra (which is immediately caudal to a disc). Knowledge that the cranial endplate of a disc is thicker and has greater bone mineral density (BMD) than the corresponding caudal endplate helps to explain this phenomenon. In this study, we investigated structural differences in vertebral trabeculae on either side of a lumbar disc to provide further insight into vertebral fracture risk. As the focus is trabecular difference within a spinal motion segment, we define cranial and caudal vertebral trabeculae relative to the disc...
November 19, 2016: Bone
https://www.readbyqxmd.com/read/27870867/preserving-posterior-complex-can-prevent-adjacent-segment-disease-following-posterior-lumbar-interbody-fusion-surgeries-a-finite-element-analysis
#5
Yun-Peng Huang, Cheng-Fei Du, Cheng-Kung Cheng, Zheng-Cheng Zhong, Xuan-Wei Chen, Gui Wu, Zhe-Cheng Li, Jin-Duo Ye, Jian-Hua Lin, Li Zhen Wang
OBJECTIVE: To investigate the biomechanical effects of the lumbar posterior complex on the adjacent segments after posterior lumbar interbody fusion (PLIF) surgeries. METHODS: A finite element model of the L1-S1 segment was modified to simulate PLIF with total laminectomy (PLIF-LAM) and PLIF with hemilaminectomy (PLIF-HEMI) procedures. The models were subjected to a 400N follower load with a 7.5-N.m moment of flexion, extension, torsion, and lateral bending. The range of motion (ROM), intradiscal pressure (IDP), and ligament force were compared...
2016: PloS One
https://www.readbyqxmd.com/read/27855352/primary-hepatic-schwannoma-a-case-report
#6
Masaki Yamamoto, Kiyoshi Hasegawa, Junichi Arita, Ryohei Maeno, Nobuhisa Akamatsu, Junichi Kaneko, Takeyuki Watadani, Naoki Okura, Akimasa Hayashi, Junji Shibahara, Yoshihiro Sakamoto, Kuni Ohtomo, Masashi Fukayama, Norihiro Kokudo
INTRODUCTION: A hepatic schwannoma is extremely rare and difficult to diagnose preoperatively. PRESENTATION OF CASE: We report the case of a 47-year-old male patient who was referred to our hospital for the close investigation of a hepatic tumor which had not been detected two years earlier. An enhanced computed tomography revealed a well-circumscribed and encapsulated tumor with a size of 50mm which was adjacent to the inferior vena cava (IVC) and the right hepatic vein...
November 9, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27836291/the-megaaortic-syndrome-progression-of-ascending-aortic-aneurysm-or-a-disease-of-distinct-origin
#7
Ulrike Baranyi, Christian Stern, Birgitta Winter, Adrian Türkcan, Bernhard Scharinger, Marie-Elisabeth Stelzmüller, Thomas Aschacher, Martin Andreas, Marek Ehrlich, Günther Laufer, David Bernhard, Barbara Messner
BACKGROUND: Thoracic aortic aneurysm (TAA) is an often asymptomatic disease with fatal outcome, such as dissection or rupture. The megaaortic syndrome (MAS) is an extensive dilatation of the whole aorta with low incidence but high lethal outcome with unknown pathophysiology so far. METHODS AND RESULTS: We compared aortic tissue of patients with sporadic TAAs and MAS of the ascending aorta with non-aneurysmal control tissues. Specimens of MAS patients showed a significantly reduced thickness of the media but an increased thickness of the intima compared to control tissue and TAAs with moderate dilatation...
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27826214/clinical-outcome-following-diam-implantation-for-symptomatic-lumbar-internal-disk-disruption-a-3-year-retrospective-analysis
#8
Kang Lu, Po-Chou Liliang, Hao-Kuang Wang, Jui-Sheng Chen, Te-Yuan Chen, Ruyi Huang, Han-Jung Chen
BACKGROUND/OBJECTIVE: Internal disk disruption (IDD), an early event of lumbar disk degeneration, is the most common cause of low back pain. Since increased intradiskal pressure (IDP) is associated with symptoms and progression of disk degeneration, unloading a painful disk with an interspinous process device (IPD) is a rational treatment option. The goal of this study was to evaluate the effectiveness of dynamic stabilization with an IPD in the treatment of symptomatic IDD of the lumbar spine...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27821712/btk-small-molecule-inhibitors-induce-a-distinct-pancreatic-toxicity-in-rats
#9
Rebecca I Erickson, Leah K Schutt, Jacqueline Tarrant, Michelle McDowell, Lichuan Liu, Adam R Johnson, Sock-Cheng Lewin-Koh, Maj Hedehus, Jed Ross, Richard A D Carano, Karin Staflin, Fiona Zhong, James Crawford, Shelly Zhong, Karin Reif, Arna Katewa, Harvey Wong, Wendy Young, Donna Dambach, Dinah Misner
Bruton's tyrosine kinase (BTK) is a member of the Tec family of cytoplasmic tyrosine kinases involved in B-cell and myeloid cell signaling. Small molecule inhibitors of BTK are being investigated for treatment of several hematological cancers and autoimmune diseases. GDC-0853 is a selective and reversible oral small molecule BTK inhibitor in development for the treatment of rheumatoid arthritis and systemic lupus erythematosus. In Sprague-Dawley (SD) rats, administration of GDC-0853 and other structurally diverse BTK inhibitors for 7 days or longer caused pancreatic lesions consisting of multifocal islet-centered hemorrhage, inflammation, fibrosis, and pigment-laden macrophages with adjacent lobular exocrine acinar cell atrophy, degeneration, and inflammation...
November 7, 2016: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/27799993/radiologic-changes-of-operated-and-adjacent-segments-after-anterior-cervical-microforaminotomy
#10
Jang Ho Ahn, Moon Sun Park, Seong Min Kim, Seung Young Chung, Do Sung Lee, Ki Seok Park
OBJECTIVE: Anterior cervical microforaminotomy (ACMF) is a motion-preserving surgical procedure. The purpose of this study is to assess radiologic changes of operated and adjacent segments after ACMF. METHODS: We retrospectively reviewed 52 patients who underwent ACMF between 1998 and 2008. From X-ray film-based changes, disc height and sagittal range of motion (ROM) of operated and adjacent segments were compared at preoperative and last follow-up periods. Radiological degeneration of both segments was analyzed as well...
September 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/27796082/pet-mri-of-metabolic-activity-in-osteoarthritis-a-feasibility-study
#11
Feliks Kogan, Audrey P Fan, Emily J McWalter, Edwin H G Oei, Andrew Quon, Garry E Gold
PURPOSE: To evaluate positron emission tomography / magnetic resonance imaging (PET/MRI) knee imaging to detect and characterize osseous metabolic abnormalities and correlate PET radiotracer uptake with osseous abnormalities and cartilage degeneration observed on MRI. MATERIALS AND METHODS: Both knees of 22 subjects with knee pain or injury were scanned at one timepoint, without gadolinium, on a hybrid 3.0T PET-MRI system following injection of (18) F-fluoride or (18) F-fluorodeoxyglucose (FDG)...
October 31, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27795801/-mesenteric-panniculitis-associated-with-acute-pancreatitis-about-a-case
#12
Hedfi Mohamed, Charfi Mehdi, Messaoudi Ikram, Moussa Myriam, Bouhawala Habib, Chouchene Adnene
Mesenteric panniculitis is a nonspecific inflammation involving the mesentery. Its clinical presentation is variable depending on the stage of the disease. Clinical signs are usually pain but half of the patients remain asymptomatic. Palpable abdominal mass, weight loss, nausea and vomiting. There may be an inflammatory syndrome of variable intensity. Panniculitis is suspected based on scan showing hyperdense mesentery with adhesions to adjacent organs. Histologically there is adipocyte degeneration causing foreign body reaction and appear lymphoplasmacytic inflammatory lesions...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27781187/kinematic-magnetic-resonance-imaging-assessment-of-the-degenerative-cervical-spine-changes-after-anterior-decompression-and-cage-fusion
#13
Marina Obradov, Menno R Bénard, Michiel M A Janssen, Patricia G Anderson, Petra J C Heesterbeek, Maarten Spruit
Study Design A prospective cohort study. Objective Decompression and fusion of cervical vertebrae is a combined procedure that has a high success rate in relieving radicular symptoms and stabilizing or improving cervical myelopathy. However, fusion may lead to increased motion of the adjacent vertebrae and cervical deformity. Both have been postulated to lead to adjacent segment pathology (ASP). Kinematic magnetic resonance imaging (MRI) has been increasingly used to evaluate range of motion (ROM) of the cervical spine and ASP...
November 2016: Global Spine Journal
https://www.readbyqxmd.com/read/27777814/kienb%C3%A3-ck-disease-and-arthroscopy-assessment-classification-and-treatment
#14
Gregory I Bain, Simon B M MacLean, Wing-Lim Tse, Pak-Cheong Ho, David M Lichtman
The assessment and management of Kienböck Disease (KD) has always been a conundrum. The Lichtman classification has traditionally been used to guide treatment based on imaging. Arthroscopy provides a direct visualization of the articular surface, allows probing of the surfaces, and enables minimally invasive techniques to be performed. The Lichtman-Bain classification is a new classification that takes into account the osseous, vascular, and cartilage aspects of the lunate and the secondary effects on the wrist...
November 2016: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/27761648/structural-and-functional-characterisation-of-a-class-i-endochitinase-of-the-carnivorous-sundew-drosera-rotundifolia-l
#15
Martin Jopcik, Jana Moravcikova, Ildiko Matusikova, Miroslav Bauer, Miroslav Rajninec, Jana Libantova
Chitinase gene from the carnivorous plant, Drosera rotundifolia , was cloned and functionally characterised. Plant chitinases are believed to play an important role in the developmental and physiological processes and in responses to biotic and abiotic stress. In addition, there is growing evidence that carnivorous plants can use them to digest insect prey. In this study, a full-length genomic clone consisting of the 1665-bp chitinase gene (gDrChit) and adjacent promoter region of the 698 bp in length were isolated from Drosera rotundifolia L...
October 19, 2016: Planta
https://www.readbyqxmd.com/read/27760063/analysis-of-segmental-mobility-following-a-novel-posterior-apical-short-segment-correction-for-adolescent-idiopathic-scoliosis
#16
Pooria Hosseini, Colin Nnadi, Ľuboš Rehák, Martin Repko, Michael Grevitt, Ufuk Aydinli, Allen Carl, Jeff Pawelek, Dennis Crandall, Behrooz A Akbarnia
STUDY DESIGN: A prospective, nonrandomized, multicenter study. OBJECTIVES: The purpose of this study was to evaluate the amount of motion present at instrumented but unfused segments and at motion segments adjacent to the instrumentation following application of a new posterior apical short-segment correction technique for correcting adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: High-density pedicle screw instrumentation and posterior arthrodesis of all instrumented levels is the most common surgical treatment for AIS stabilization...
October 15, 2016: Spine
https://www.readbyqxmd.com/read/27755207/imaging-evaluation-and-relative-significance-in-cases-of-cervical-disk-allografting-radiographic-character-after-total-disk-transplantation
#17
Yu Ding, Di-Ke Ruan, Qing He, Li Sheng Hou, Jian Ning Lin, Hong Peng Cui
STUDY DESIGN: The clinical and radiologic data of total disk allografting (TDA) cases were collected and analyzed to explore the correlation between neurological function improvements and imaging changes. OBJECTIVE: The aim of the study was to assess the medium-term and long-term outcome and radiographic character after TDA, and, furthermore, to explore the significance of the changes of imaging signs after the transplantation. SUMMARY OF BACKGROUND DATA: Spinal fusion may result in the adjacent segment degeneration...
November 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27755201/radiographic-adjacent-segment-degeneration-at-5-years-after-l4-5-posterior-lumbar-interbody-fusion-with-pedicle-screw-instrumentation-evaluation-by-computed-tomography-and-annual-screening-with-magnetic-resonance-imaging
#18
Shiro Imagama, Noriaki Kawakami, Yuji Matsubara, Taichi Tsuji, Tetsuya Ohara, Yoshito Katayama, Naoki Ishiguro, Tokumi Kanemura
STUDY DESIGN: Retrospective clinical study. OBJECTIVE: To investigate adjacent segment degeneration (ASD) at 5 years after L4/5 posterior lumbar interbody fusion with pedicle screw instrumentation and L4/5 decompression surgery using plain radiographs, computed tomography (CT), and magnetic resonance imaging (MRI), with the evaluation of annual changes on MRI. SUMMARY OF BACKGROUND DATA: Methods of evaluation have been inconsistent among studies of ASD...
November 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27753523/golgi-proteins-in-circulating-human-platelets-are-distributed-across-non-stacked-scattered-structures
#19
Shilpi Yadav, Jonathan K Williamson, Maria A Aronova, Andrew A Prince, Irina D Pokrovskaya, Richard D Leapman, Brian Storrie
Platelets are small, anucleate cell fragments that are central to hemostasis, thrombosis, and inflammation. They are derived from megakaryocytes from which they inherit their organelles. As platelets can synthesize proteins and contain many of the enzymes of the secretory pathway, one might expect all mature human platelets to contain a stacked Golgi apparatus, the central organelle of the secretory pathway. By thin section electron microscopy, stacked membranes resembling the stacked Golgi compartment in megakaryocytes and other nucleated cells can be detected in both proplatelets and platelets...
October 18, 2016: Platelets
https://www.readbyqxmd.com/read/27749265/occurrence-of-intersex-in-wild-freshwater-fish-in-slovenian-rivers-a-histological-evaluation
#20
Milka Vrecl, Vlasta Jenčič
The aim of this preliminary research was to establish if there are intersex occurrences in wild freshwater fish in Slovenian rivers and streams. In the first study we evaluated all fish species of both sexes obtained from the river Ljubljanica from its source to mouth. In the second study we focused on the rainbow trout (Oncorhynchus mykiss) and brown trout (Salmo trutta m. fario) males from 30 rivers and streams in different parts of Slovenia. The male gonads were histologically assessed for the presence of oocytes to determine the frequency and degree of intersex...
September 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
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