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Diego Munguia-Izquierdo, Luis Suarez-Arrones, Valter Di Salvo, Victor Paredes-Hernandez, Julian Alcazar, Ignacio Ara, Richard Kreider, Alberto Mendez-Villanueva
This study determined the most effective field method for quantifying body fat percentage in male elite youth soccer players and developed prediction equations based on anthropometric variables. Forty-four male elite-standard youth soccer players aged 16.3-18.0 years underwent body fat percentage assessments, including bioelectrical impedance analysis and the calculation of various skinfold-based prediction equations. Dual X-ray absorptiometry provided a criterion measure of body fat percentage. Correlation coefficients, bias, limits of agreement, and differences were used as validity measures, and regression analyses were used to develop soccer-specific prediction equations...
March 21, 2018: International Journal of Sports Medicine
Athena E Theyers, Benjamin I Goldstein, Arron Ws Metcalfe, Andrew D Robertson, Bradley J MacIntosh
Arterial stiffness is linked to cerebral small vessel damage and neurodegeneration, but barriers to accessing deep cerebrovascular anatomy limit our ability to assess the brain. This study describes an adaptation of a cardiac-related scrubbing method as a means of generating blood oxygenation level-dependent pulsatility maps based on the cardiac cycle. We examine BOLD pulsatility at rest, based on the non-parametric deviation from null metric, as well as changes following acute physiological stress from 20 min of moderate-intensity cycling in 45 healthy adolescents...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
Alhassane Diallo, Heike Jacobi, Arron Cook, Robyn Labrum, Alexandra Durr, Alexis Brice, Perrine Charles, Cecilia Marelli, Caterina Mariotti, Lorenzo Nanetti, Marta Panzeri, Maria Rakowicz, Anna Sobanska, Anna Sulek, Tanja Schmitz-Hübsch, Ludger Schöls, Holger Hengel, Bela Melegh, Alessandro Filla, Antonella Antenora, Jon Infante, José Berciano, Bart P van de Warrenburg, Dagmar Timmann, Sylvia Boesch, Massimo Pandolfo, Jörg B Schulz, Peter Bauer, Paola Giunti, Jun-Suk Kang, Thomas Klockgether, Sophie Tezenas du Montcel
BACKGROUND: Spinocerebellar ataxias are dominantly inherited progressive ataxia disorders that can lead to premature death. We aimed to study the overall survival of patients with the most common spinocerebellar ataxias (SCA1, SCA2, SCA3, and SCA6) and to identify the strongest contributing predictors that affect survival. METHODS: In this longitudinal cohort study (EUROSCA), we enrolled men and women, aged 18 years or older, from 17 ataxia referral centres in ten European countries; participants had positive genetic test results for SCA1, SCA2, SCA3, or SCA6 and progressive, otherwise unexplained, ataxias...
April 2018: Lancet Neurology
Salman Siddiqui, Aarti Shikotra, Matthew Richardson, Emma Doran, David Choy, Alex Bell, Cary D Austin, Jeffrey Eastham-Anderson, Beverley Hargadon, Joseph R Arron, Andrew Wardlaw, Christopher E Brightling, Liam G Heaney, Peter Bradding
BACKGROUND: Asthma is a complex chronic disease underpinned by pathological changes within the airway wall. How variations in structural airway pathology and cellular inflammation contribute to the expression and severity of asthma are poorly understood. OBJECTIVES: Therefore we evaluated pathological heterogeneity using topological data analysis (TDA) with the aim of visualizing disease clusters and microclusters. METHODS: A discovery population of 202 adult patients (142 asthmatic patients and 60 healthy subjects) and an external replication population (59 patients with severe asthma) were evaluated...
March 7, 2018: Journal of Allergy and Clinical Immunology
Melody J Xu, Ann A Lazar, Adam A Garsa, Sarah T Arron, William R Ryan, Ivan H El-Sayed, Jonathan R George, Alain P Algazi, Chase M Heaton, Patrick K Ha, Sue S Yom
BACKGROUND: The purpose of this study was to assess changes resulting from the American Joint Committee on Cancer (AJCC) eighth edition for cutaneous squamous cell carcinoma (SCC) and evaluate pertinent excluded factors. METHODS: In 101 patients receiving surgery and postoperative radiation, recurrence and survival were estimated by cumulative incidence and Kaplan-Meier method. Time-to-event analysis was performed using Cox proportional hazards and Fine-Gray competing risks regression models...
March 10, 2018: Head & Neck
William King, Arron Lacey, James White, Daniel Farewell, Frank Dunstan, David Fone
BACKGROUND: Coronary heart disease (CHD) mortality in England fell by 36% between 2000 and 2007 and it is estimated that approximately 50% of the fall was due to improved treatment uptake. Marked socio-economic inequalities in CHD mortality in the United Kingdom (UK) remain, with higher age-adjusted rates in more deprived groups. Inequalities in the persistence of medication for primary and secondary prevention of CHD may contribute to the observed social gradient and we investigated this possibility in the population of Wales (UK)...
2018: PloS One
David Saceda-Corralo, Cristina Pindado-Ortega, Óscar Muñoz Moreno-Arrones, Pablo Fernández-González, Ana Rita Rodrigues-Barata, Pedro Jaén-Olasolo, Sergio Vañó-Galván
No abstract text is available yet for this article.
March 7, 2018: JAMA Dermatology
Weizhen Liu, Yukiko Naruoka, Kaitlin Miller, Kimberly A Garland-Campbell, Arron H Carter
Stripe rust resistance is a critical need for wheat cultivars in the US Pacific Northwest (PNW). Our previous genome-wide association study (GWAS) for stripe rust resistance in a set of PNW winter wheat accessions (Panel-2) identified multiple marker-trait associations (MTAs) for both all-stage and field resistance. In this study, we conducted additional GWAS using a different set of PNW winter wheat accessions (Panel-1) that contained recently bred soft white winter wheat breeding lines and cultivars. A total of 12 all-stage resistance MTAs and eight field resistance MTAs were identified...
March 2018: Plant Genome
Shantel A Martinez, Jayfred Godoy, Meng Huang, Zhiwu Zhang, Arron H Carter, Kimberly A Garland Campbell, Camille M Steber
Preharvest sprouting (PHS), the germination of grain on the mother plant under cool and wet conditions, is a recurring problem for wheat farmers worldwide. α-amylase enzyme produced during PHS degrades starch resulting in baked good with poor end-use quality. The Hagberg-Perten Falling Number (FN) test is used to measure this problem in the wheat industry, and determines how much a farmer's wheat is discounted for PHS damage. PHS tolerance is associated with higher grain dormancy. Thus, breeding programs use germination-based assays such as the spike-wetting test to measure PHS susceptibility...
2018: Frontiers in Plant Science
Yi Gao, Sarah T Arron, Eleni Linos, Ingrid Polcari, Matthew D Mansh
No abstract text is available yet for this article.
February 28, 2018: JAMA Dermatology
Alvi H Islam, Arron W S Metcalfe, Bradley J MacIntosh, Daphne J Korczak, Benjamin I Goldstein
BACKGROUND: Higher body mass index (BMI) and obesity is common among youth with bipolar disorder (BD) and is associated with greater psychiatric illness severity, including suicidality. Obesity has been associated with frontal, temporal and subcortical volumetric reductions in adults with BD. We examined the neurostructural correlates of BMI in adolescents early in their course of BD. METHODS: We processed T 1 -weighted images of adolescents with BD and psychiatrically healthy controls using FreeSurfer to derive a priori region of interest (ROI) volumes/cortical thickness for the frontal lobe (FL), prefrontal cortex (PFC) and orbitofrontal cortex (OFC) as well as volumes for the amygdala and hippocampus...
March 2018: Journal of Psychiatry & Neuroscience: JPN
Cristina Pindado-Ortega, David Saceda-Corralo, Laura Miguel-Gómez, Diego Buendía-Castaño, Pablo Fernández-González, Oscar M Moreno-Arrones, Pablo Fonda-Pascual, Adrian Alegre-Sánchez, Rita Rodrigues-Barata, Sergio Vañó-Galván
Folliculitis decalvans (FD) is a primary neutrophilic scarring alopecia characterized by perifollicular papules, crusts, and pustules frequently located on the vertex. FD may affect young men and women. Since it may lead to hair loss, it can have a negative impact on patients' quality of life. Nevertheless, studies have focused on clinical, prognostic, and therapeutic aspects without considering the psychological impact of FD. In our study, we found that FD patients experienced a considerable impact on their quality of life...
January 2018: Skin Appendage Disorders
Cristina Pindado-Ortega, David Saceda-Corralo, Diego Buendía-Castaño, Pablo Fernández-González, Óscar M Monero-Arrones, Pablo Fonda-Pascual, Ana R Rodrigues-Barata, Pedro Jaén-Olasolo, Sergio Vañó-Galván
No abstract text is available yet for this article.
March 2018: Journal of the American Academy of Dermatology
Adrian Alegre-Sanchez, Natalia Jiménez-Gómez, Óscar M Moreno-Arrones, Pablo Fonda-Pascual, Bibiana Pérez-García, Pedro Jaén-Olasolo, Pablo Boixeda
The novel picosecond lasers, initially developed for faster tattoo removal, have also shown great efficacy in endogenous pigmentary disorders. To describe the efficacy and safety profile of an alexandrite (755-nm) picosecond laser in a wide range of pigmented flat and elevated cutaneous lesions. A retrospective study was performed in which we collected all the clinical images of patients treated with the 755-nm alexandrite picosecond laser for 12 months (November 2016-November 2017). Clinical features were obtained from their medical charts...
February 9, 2018: Lasers in Medical Science
Oscar M Moreno-Arrones, Rosario Carrillo-Gijon, Elena Sendagorta, Luis Rios-Buceta
No abstract text is available yet for this article.
March 2018: JAAD Case Reports
Yi Gao, Sarah T Arron, Amanda K Raymond
No abstract text is available yet for this article.
January 2018: JAAD Case Reports
Catherine E Hanratty, John G Matthews, Joseph R Arron, David F Choy, Ian D Pavord, P Bradding, Christopher E Brightling, Rekha Chaudhuri, Douglas C Cowan, Ratko Djukanovic, Nicola Gallagher, Stephen J Fowler, Tim C Hardman, Tim Harrison, Cécile T Holweg, Peter H Howarth, James Lordan, Adel H Mansur, Andrew Menzies-Gow, Sofia Mosesova, Robert M Niven, Douglas S Robinson, Dominick E Shaw, Samantha Walker, Ashley Woodcock, Liam G Heaney
BACKGROUND: Patients with difficult-to-control asthma consume 50-60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients with asthma have a typical type 2 (T2)-driven eosinophilic inflammation. These asthmatics have been called 'T2-low asthma' and have a minimal response to corticosteroid therapy. Adjustment of corticosteroid treatment using sputum eosinophil counts from induced sputum has demonstrated reduced severe exacerbation rates and optimized corticosteroid dose...
January 4, 2018: Trials
Moisés de Hoyo, Borja Sañudo, Luis Suárez-Arrones, Luis Carrasco, Tom Joel, Sergio Domínguez-Cobo, Francisco J Núñez
BACKGROUND: The aim of the current study was to analyse the acceleration profile in elite professional soccer players according to their initial speed but also considering players' position. METHODS: Players' accelerations profiles were analysed using a relative acceleration profile according to the initial speed (S1, from 0 to 7 km/h; S2, from 7.1 to 14.3 km/h; and S3, ≥14.4 km/h) and the maximum acceleration. RESULTS: Within-group analyses showed that Center Backs (CB) performed more high intensity accelerations (likely) when they started in S1 than S2 (ES: 0...
December 1, 2017: Journal of Sports Medicine and Physical Fitness
Pablo Fonda-Pascual, Oscar M Moreno-Arrones, David Saceda-Corralo, Ana R Rodrigues-Barata, Cristina Pindado-Ortega, Pablo Boixeda, Sergio Vaño-Galvan
No abstract text is available yet for this article.
December 1, 2017: Journal of the American Academy of Dermatology
C A Harwood, S T Arron, C M Proby, M M Asgari, J N Bouwes Bavinck, A C Green, A E Toland
No abstract text is available yet for this article.
November 2017: British Journal of Dermatology
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