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https://www.readbyqxmd.com/read/29450738/double-blind-randomized-controlled-clinical-trial-on-analgesic-efficacy-of-local-anesthetics-articaine-and-bupivacaine-after-impacted-third-molar-extraction
#1
Maria Victoria Olmedo-Gaya, Francisco Javier Manzano-Moreno, Jose Luis Muñoz-López, Manuel Francisco Vallecillo-Capilla, Candela Reyes-Botella
OBJECTIVE: The objective of this randomized controlled clinical trial (RCT) was to compare the effect of bupivacaine and articaine at habitual doses on pain intensity and the need for analgesics after lower third molar extraction. MATERIALS AND METHODS: The final study sample comprised 50 Caucasian volunteers (26 males and 24 females; age range, 18-30 years) undergoing scheduled surgical extraction of impacted lower third molar. A computer-generated random sequence was used to allocate participants to the articaine (4%) or bupivacaine (0...
February 15, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29443404/new-immunomodulatory-oral-nutrition-formula-for-use-prior-to-surgery-in-patients-with-head-and-neck-cancer-an-exploratory-study
#2
Samara Palma-Milla, Bricia López-Plaza, Beatriz Santamaría, Álvaro de Arriba-Sánchez, Laura M Bermejo, Carmen Gómez-Candela
BACKGROUND: The perioperative use of immunomodulatory nutrition formulas in patients with head and neck cancer reduces the number of postoperative infections and the length of hospital stay. OBJECTIVE: An exploratory, randomized, controlled, blind, clinical trial was designed to examine the effect of the preoperative consumption of a new, immunomodulatory, oral nutrition formula in patients with head and neck cancer. METHODS: Thirty-eight patients were randomized to receive either 400 mL/d of either the new immunomodulatory formula (IF) or that commonly used in clinical practice (CF) over 10 days prior to surgery...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29428153/chronic-renal-disease-in-spain-prevalence-and-related-factors-in-persons-with-diabetes-mellitus-older-than-64-years
#3
Juan Martínez Candela, Javier Sangrós González, Francisco Javier García Soidán, José Manuel Millaruelo Trillo, Javier Díez Espino, Daniel Bordonaba Bosque, Luis Ávila Lachica
INTRODUCTION: Type 2 diabetes mellitus and chronic kidney disease (CKD) are conditions which have a high prevalence in individuals ≥ 65 years of age and represent a major public health problem. OBJECTIVES: To determine the prevalence of CKD, its categories and its relationship with various demographic and clinical factors in elderly patients with type 2 diabetes mellitus in Spain. METHODS: Observational, cross-sectional, multicenter, Spanish epidemiological study...
February 7, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29426306/characteristics-of-people-living-in-italy-after-a-cancer-diagnosis-in-2010-and-projections-to-2020
#4
Stefano Guzzinati, Saverio Virdone, Roberta De Angelis, Chiara Panato, Carlotta Buzzoni, Riccardo Capocaccia, Silvia Francisci, Anna Gigli, Manuel Zorzi, Giovanna Tagliabue, Diego Serraino, Fabio Falcini, Claudia Casella, Antonio Giampiero Russo, Fabrizio Stracci, Bianca Caruso, Maria Michiara, Anna Luisa Caiazzo, Marine Castaing, Stefano Ferretti, Lucia Mangone, Giuseppa Rudisi, Flavio Sensi, Guido Mazzoleni, Fabio Pannozzo, Rosario Tumino, Mario Fusco, Paolo Ricci, Gemma Gola, Adriano Giacomin, Francesco Tisano, Giuseppa Candela, Anna Clara Fanetti, Filomena Pala, Antonella Sutera Sardo, Massimo Rugge, Laura Botta, Luigino Dal Maso
BACKGROUND: Estimates of cancer prevalence are widely based on limited duration, often including patients living after a cancer diagnosis made in the previous 5 years and less frequently on complete prevalence (i.e., including all patients regardless of the time elapsed since diagnosis). This study aims to provide estimates of complete cancer prevalence in Italy by sex, age, and time since diagnosis for all cancers combined, and for selected cancer types. Projections were made up to 2020, overall and by time since diagnosis...
February 9, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29417665/pulmonary-and-hepatic-cystic-lesions-in-a-child
#5
Alba Rubio-San-Simón, Luis Miguel García-Cárdaba, Jorge Candela-Herrera
No abstract text is available yet for this article.
February 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29407095/determinants-of-exercise-intolerance-in-heart-failure-with-preserved-ejection-fraction-a-systematic-review-and-meta-analysis
#6
David Montero, Candela Diaz-Cañestro
BACKGROUND: Severe exercise intolerance (EI), demonstrated by impaired peak oxygen consumption, intrinsically characterizes heart failure with preserved ejection fraction (HFpEF). Controversy exists on the determinants of EI in patients with HFpEF according to case-control studies. The purpose of this study is to systematically review and clarify the main (Fick) determinants of EI in HFpEF. METHODS: We conducted a systematic search of MEDLINE, Scopus and Web of Science since their inceptions until January 2017 for articles assessing peak cardiac output and/or arteriovenous oxygen difference (a-vO2diffpeak) with incremental exercise in patients diagnosed with HFpEF and age-matched control individuals...
March 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29386661/amrz-is-a-major-determinant-of-c-di-gmp-levels-in-pseudomonas-fluorescens-f113
#7
Candela Muriel, Eva Arrebola, Miguel Redondo-Nieto, Francisco Martínez-Granero, Blanca Jalvo, Sebastian Pfeilmeier, Esther Blanco-Romero, Irene Baena, Jacob G Malone, Rafael Rivilla, Marta Martín
The transcriptional regulator AmrZ is a global regulatory protein conserved within the pseudomonads. AmrZ can act both as a positive and a negative regulator of gene expression, controlling many genes implicated in environmental adaption. Regulated traits include motility, iron homeostasis, exopolysaccharides production and the ability to form biofilms. In Pseudomonas fluorescens F113, an amrZ mutant presents a pleiotropic phenotype, showing increased swimming motility, decreased biofilm formation and very limited ability for competitive colonization of rhizosphere, its natural habitat...
January 31, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29385162/the-balance-between-apoptosis-and-autophagy-regulates-testis-regression-and-recrudescence-in-the-seasonal-breeding-south-american-plains-vizcacha-lagostomus-maximus
#8
Candela R González, María L Muscarsel Isla, Alfredo D Vitullo
Mammalian testis undergoes deep changes in their architecture and function during photoregression conditions in seasonal breeders. Particularly, the testicular mechanisms that regulate the transition between the active (functional) and inactive (regression) stage vary between species. The aim of the present study was to analyze the incidence of proliferation, apoptosis and autophagy in the testicular seminiferous ephitelium of a seasonal breeder, Lagostomus maximus, during the annual reproductive cycle. We observed that proliferating spermatogonia increased from the active testis until reaching the maximum peak in the activating testis...
2018: PloS One
https://www.readbyqxmd.com/read/29381100/express-multiwavelength-raman-spectroscopic-analysis-of-superficial-iron-chromium-oxides-generated-using-laser-irradiation
#9
Martin Ortiz Morales, Juan Jose Soto Bernal, Claudio Frausto-Reyes, Sofia E Acosta Ortiz, Rosario Gonzalez Mota, Iliana Rosales Candelas
No abstract text is available yet for this article.
January 1, 2018: Applied Spectroscopy
https://www.readbyqxmd.com/read/29365865/implication-of-the-mediterranean-diet-and-physical-exercise-on-the-lipid-profile-based-on-1h-nmr-spectroscopy-of-metabolically-healthy-obese-women-mho
#10
Enrique Rodríguez-García, Josefina Ruiz-Nava, Sonia Santamaria-Fernandez, Jose Carlos Fernández-Garcia, Antonio Vargas Candela, Raquel Yahyaoui, Francisco Tinahones, Maria Rosa Bernal-Lopez, Ricardo Gomez-Huelgas
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29359385/clinical-study-to-evaluate-the-performance-of-a-noninvasive-focused-ultrasound-device-for-thigh-fat-and-circumference-reduction-compared-to-control
#11
Eric C Wilkerson, Bradley S Bloom, David J Goldberg
BACKGROUND AND OBJECTIVES: An FDA-cleared focused ultrasound device (UltraShape, Syneron Candela® , Yokneam, Israel) for noninvasive abdominal fat reduction produces localized mechanical cellular membrane disruption in adipocytes. This study seeks to determine the safety and efficacy of this device for use on the thighs. STUDY DESIGNS/MATERIALS AND METHODS: Fourteen women aged 33-60 were selected to receive 3 biweekly treatments to one thigh with the other thigh serving as an internal control...
January 22, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29347861/positive-emotional-attention-bias-in-young-children-with-symptoms-of-adhd
#12
Amanda Cremone, Claudia I Lugo-Candelas, Elizabeth A Harvey, Jennifer M McDermott, Rebecca M C Spencer
Children with attention-deficit/hyperactivity disorder (ADHD) often experience emotional dysregulation. Dysregulation can arise from heightened attention to emotional stimuli. Emotional attention biases are associated with a number of adverse socioemotional outcomes including reward sensitivity and externalizing behaviors. As reward sensitivity and externalizing behaviors are common in children with ADHD, the aim of the current study was to determine whether emotional attention biases are evident in young children with clinically significant ADHD symptoms...
January 18, 2018: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/29343133/central-nervous-system-malformation-associated-with-methamphetamine-abuse-during-pregnancy
#13
Silvia Maya-Enero, Júlia Candel-Pau, Mónica Rebollo-Polo, Santiago Candela-Cantó, Rafael de la Torre, María Ángeles López-Vílchez
INTRODUCTION: Prenatal methamphetamine exposure is related to prematurity, fetal growth restriction, neurobehavioral effects and long-term motor and cognitive sequelae. PATIENT PRESENTATION: We report the case of a newborn from a Filipina with no prenatal care with a complex brain malformation. Methamphetamine was identified in maternal and neonatal urine and in maternal hair, raising our suspicion of methamphetamine as a cause of this malformation. DISCUSSION: Methamphetamine abuse is a growing problem worldwide...
January 17, 2018: Clinical Toxicology
https://www.readbyqxmd.com/read/29330797/testing-acute-oxygen-sensing-in-genetically-modified-mice-plethysmography-and-amperometry
#14
Patricia Ortega-Sáenz, Candela Caballero, Lin Gao, José López-Barneo
Monitoring responsiveness to acute hypoxia of whole animals and single cells is essential to investigate the nature of the mechanisms underlying oxygen (O2) sensing. Here we describe the protocols followed in our laboratory to evaluate the ventilatory response to hypoxia in normal and genetically modified animals. We also describe the amperometric technique used to monitor single-cell catecholamine release from chemoreceptor cells in carotid body and adrenal medulla slices.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29329291/ovule-identity-mediated-by-pre-mrna-processing-in-arabidopsis
#15
Encarnación Rodríguez-Cazorla, Samanta Ortuño-Miquel, Héctor Candela, Lindsay J Bailey-Steinitz, Martin F Yanofsky, Antonio Martínez-Laborda, Juan-José Ripoll, Antonio Vera
Ovules are fundamental for plant reproduction and crop yield as they are the precursors of seeds. Therefore, ovule specification is a critical developmental program. In Arabidopsis thaliana, ovule identity is redundantly conferred by the homeotic D-class genes SHATTERPROOF1 (SHP1), SHP2 and SEEDSTICK (STK), phylogenetically related to the MADS-domain regulatory gene AGAMOUS (AG), essential in floral organ specification. Previous studies have shown that the HUA-PEP activity, comprised of a suite of RNA-binding protein (RBP) encoding genes, regulates AG pre-mRNA processing and thus flower patterning and organ identity...
January 12, 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29325576/reanalysis-of-chinese-treponema-pallidum-samples-all-chinese-samples-cluster-with-ss14-like-group-of-syphilis-causing-treponemes
#16
Michal Strouhal, Jan Oppelt, Lenka Mikalová, Natasha Arora, Kay Nieselt, Fernando González-Candelas, David Šmajs
OBJECTIVE: Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have revealed two genetically distinct groups of syphilis-causing treponemes, called Nichols-like and SS14-like groups. So far, no genetic intermediates, i.e. strains containing a mixed pattern of Nichols-like and SS14-like genomic sequences, have been identified. Recently, Sun et al. (Oncotarget 2016. https://doi.org/10.18632/oncotarget...
January 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29325527/single-center-experience-with-laparoscopic-adrenalectomy-on-a-large-clinical-series
#17
Giovanni Conzo, Claudio Gambardella, Giancarlo Candela, Alessandro Sanguinetti, Andrea Polistena, Guglielmo Clarizia, Renato Patrone, Francesco Di Capua, Chiara Offi, Mario Musella, Sergio Iorio, Giseppe Bellastella, Daniela Pasquali, Annamaria De Bellis, Antonio Sinisi, Nicola Avenia
BACKGROUND: Laparoscopic adrenalectomy is considered the gold standard technique for the treatment of benign small and medium size adrenal masses (<6 cm), due to low morbidity rate, short hospitalization and patient rapid recovery. The aim of our study is to analyse the feasibility and efficiency of this surgical approach in a broad spectrum of adrenal gland pathologies. METHODS: Pre-operative, intra-operative and post-operative data from 126 patients undergone laparoscopic adrenalectomy between January 2003 and December 2015 were retrospectively collected and reviewed...
January 11, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29325030/the-effect-of-rna-substitution-models-on-viroid-and-rna-virus-phylogenies
#18
Juan Ángel Patiño Galindo, Fernando González Candelas, Oliver G Pybus
Many viroids and RNA viruses have genomes that exhibit secondary structure, with paired nucleotides forming stems and loops. Such structures violate a key assumption of most methods of phylogenetic reconstruction, that sequence change is independent among sites. However, phylogenetic analyses of these transmissible agents rarely use evolutionary models that account for RNA secondary structure. Here we assess the effect of using RNA-specific nucleotide substitution models on the phylogenetic inference of viroids and RNA viruses...
January 9, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29319652/pain-assessment-in-mechanically-ventilated-noncommunicative-severe-trauma-patients
#19
Candelas López-López, Teresa Pérez-Pérez, Juan Vicente Beneit-Montesinos, José Luis García-Klepzig, Mercedes Virginia Martinez-Ureta, María Del Ara Murillo-Pérez, Silvia Ana Torrente-Vela, Mónica García-Iglesias
The aim of this study was to measure pain levels in noncommunicative patients with severe trauma who required tracheal suctioning and mobilization and to determine the utility of the Behavioral Indicators of Pain Scale (ESCID) in these cases. The pain scores for the procedures were recorded on Days 1, 3, and 6 of the patients' stay in the intensive care unit. These assessments were performed at 3 moments: before, during, and after the application of the procedures. Because of the longitudinal character of the study, data were fitted into a multivariate model using the Generalized Estimating Equations method...
January 2018: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/29318917/the-effectiveness-of-combining-inspiratory-muscle-training-with-manual-therapy-and-a-therapeutic-exercise-program-on-maximum-inspiratory-pressure-in-adults-with-asthma-a-randomized-clinical-trial
#20
Ibai López-de-Uralde-Villanueva, Pablo Candelas-Fernández, Beatriz de-Diego-Cano, Orcález Mínguez-Calzada, Tamara Del Corral
OBJECTIVE: The objective of this study was to evaluate whether the addition of manual therapy and therapeutic exercise protocol to inspiratory muscle training was more effective in improving maximum inspiratory pressure than inspiratory muscle training in isolation. DESIGN: This is a single-blinded, randomized controlled trial. SUBJECTS: In total, 43 patients with asthma were included in this study. INTERVENTIONS: The patients were allocated into one of the two groups: (1) inspiratory muscle training ( n = 21; 20-minute session) or (2) inspiratory muscle training (20-minute session) combined with a program of manual therapy (15-minute session) and therapeutic exercise (15-minute session; n = 22)...
January 1, 2018: Clinical Rehabilitation
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