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https://www.readbyqxmd.com/read/28819829/surgical-treatment-for-symptomatic-non-ossifying-fibromas-of-the-lower-extremity-with-calcium-sulfate-grafts-in-skeletally-immature-patients
#1
Antonio Andreacchio, Flavia Alberghina, Gianluca Testa, Federico Canavese
BACKGROUND: Non-ossifying fibromas (NOFs) are common benign bone lesions found in children and adolescents. They usually involve metaphysis of long bones, tend to gradually disappear with age and usually do not require surgery, while they are not associated with pathological fractures. The aim of this study was to evaluate the outcome and efficacy of a single-stage procedure, comprising curettage of the lesion and calcium sulfate pellet (CaSP) grafting, in skeletally immature patients with large, symptomatic NOF of the lower extremity, and the possible limitations of the procedure...
August 17, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28818204/geometry-as-a-confounder-when-assessing-ventricular-systolic-function-comparison-between-ejection-fraction-and-strain
#2
Thomas M Stokke, Nina E Hasselberg, Marit K Smedsrud, Sebastian I Sarvari, Kristina H Haugaa, Otto A Smiseth, Thor Edvardsen, Espen W Remme
BACKGROUND: Preserved left ventricular (LV) ejection fraction (EF) and reduced myocardial strain are reported in patients with hypertrophic cardiomyopathy, ischemic heart disease, diabetes mellitus, and more. OBJECTIVES: The authors performed a combined mathematical and echocardiographic study to understand the inconsistencies between EF and strains. METHODS: An analytical equation showing the relationship between EF and the 4 parameters, global longitudinal strain (GLS), global circumferential strain (GCS), wall thickness, and short-axis diameter, was derived from an elliptical LV model...
August 22, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28817244/key-developments-that-impacted-the-field-of-mechanobiology-and-mechanotransduction
#3
Michelle Wall, David Butler, Alicia El Haj, Josephine C Bodle, Elizabeth G Loboa, Albert J Banes
Advances in mechanobiology have evolved through insights from multiple disciplines including structural engineering, biomechanics, vascular biology, and orthopaedics. In this paper, we reviewed the impact of key reports related to the study of applied loads on tissues and cells and the resulting signal transduction pathways. We addressed how technology has helped advance the burgeoning field of mechanobiology (over 33,600 publications from 1970-2016). We analyzed the impact of critical ideas and then determined how these concepts influenced the mechanobiology field by looking at the citation frequency of these reports as well as tracking how the overall number of citations within the field changed over time...
August 17, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28816296/-complete-androgen-insensitivity-syndrome-associated-with-vesical-fistula-a-case-report-and-literature-review
#4
K H Hua, L Yang, X W Zhang, W J Bai, Q Li, T Xu
Androgen insensitivity syndrome (AIS) is a very uncommon genetic disorder that results from the resistance of androgen receptor (AR) to androgen, which influences the formation of the male genitalia and in turn presents with female phenotype. Surgical resection of undesceaded testicle and different kinds of genitoplasty are crucial methods to correct the deformity of reproductive system, as well as hormone replacement therapy, which is an essential therapy for postoperational rehabilitation in AIS patients...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28815378/effect-of-aging-on-mechanical-stresses-deformations-and-hemodynamics-in-human-femoropopliteal-artery-due-to-limb-flexion
#5
Anastasia Desyatova, Jason MacTaggart, Rodrigo Romarowski, William Poulson, Michele Conti, Alexey Kamenskiy
Femoropopliteal artery (FPA) reconstructions are notorious for poor clinical outcomes. Mechanical and flow conditions that occur in the FPA with limb flexion are thought to play a significant role, but are poorly characterized. FPA deformations due to acute limb flexion were quantified using a human cadaver model and used to build a finite element model that simulated surrounding tissue forces associated with limb flexion-induced deformations. Strains and intramural principal mechanical stresses were determined for seven age groups...
August 16, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28803112/in-vivo-documentation-of-shape-and-position-changes-of-mri-visible-mesh-placed-in-rectovaginal-septum
#6
Urbankova Iva, Sindhwani Nikhil, Callewaert Geertje, Turri Alice, Rinkijevic Rita, Hympanova Lucie, Feola Andrew, Deprest Jan
BACKGROUND AND OBJECTIVE: Large deformations in synthetic meshes used in pelvic organ prolapse surgery may lead to suboptimal support for the underlying tissue, graft-related complications as well as recurrence. Our aim was to quantify in vivo longitudinal changes in mesh shape and geometry in a large animal model. We compare two commonly used mesh shapes, armed and flat, that are differently affixed. The secondary outcomes were active and passive biomechanical properties. METHODS: A total of 18 animals were used...
August 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28801894/increased-apical-rotation-in-patients-with-severe-aortic-stenosis-assessed-by-three-dimensional-speckle-tracking-imaging
#7
Maidar Tumenbayar, Kazuto Yamaguchi, Hiroyuki Yoshitomi, Akihiro Endo, Kazuaki Tanabe
BACKGROUND: Two-dimensional (2D) speckle tracking imaging (STI) is a non-invasive method used to assess subtle changes in left ventricular (LV) function such as strain and rotational dynamics. However, 2D methodology is complicated by issues such as the out-of-plane problem inherent in short-axis imaging. In addition, circumferential rotation contributes to three-dimensional (3D) wall deformations and affects tracking accuracy. By using 3D-STI technique, we evaluated LV global longitudinal strain (GLS) and apical rotation in severe aortic stenosis (AS) patients with preserved LV ejection fraction (EF)...
August 11, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28801801/nuclear-envelope-a-new-frontier-in-plant-mechanosensing
#8
REVIEW
Kateryna Fal, Atef Asnacios, Marie-Edith Chabouté, Olivier Hamant
In animals, it is now well established that forces applied at the cell surface are propagated through the cytoskeleton to the nucleus, leading to deformations of the nuclear structure and, potentially, to modification of gene expression. Consistently, altered nuclear mechanics has been related to many genetic disorders, such as muscular dystrophy, cardiomyopathy and progeria. In plants, the integration of mechanical signals in cell and developmental biology has also made great progress. Yet, while the link between cell wall stresses and cytoskeleton is consolidated, such cortical mechanical cues have not been integrated with the nucleoskeleton...
August 12, 2017: Biophysical Reviews
https://www.readbyqxmd.com/read/28798988/hemodynamic-assessments-of-the-ascending-thoracic-aortic-aneurysm-using-fluid-structure-interaction-approach
#9
Han Hung Yeh, Simon W Rabkin, Dana Grecov
Current assessment and management of ascending thoracic aortic aneurysm (ATAA) rely heavily on the diameter of the ATAA and blood pressure rather than biomechanical and hemodynamic parameters such as arterial wall deformation or wall shear stress. The objective of the current study was to develop an accurate computational method for modeling the mechanical responses of the ATAA to provide additional information in patient evaluations. Fully coupled fluid structure interaction simulations were conducted using data from cases with ATAA with measured geometrical parameters in order to evaluate and analyze the change in biomechanical responses under normotensive and hypertensive conditions...
August 11, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28793225/multiscale-and-multiaxial-mechanics-of-vascular-smooth-muscle
#10
Sae-Ii Murtada, Jay D Humphrey, Gerhard A Holzapfel
Mathematical models can facilitate an integrative understanding of the complexity underlying biological structure and function, but they must be informed and validated by empirical data. Uniaxial contraction of an arterial ring is a well-used in vitro approach for studying characteristics of smooth muscle contractility even though this experimental arrangement does not mimic the in vivo vascular geometry or loading. In contrast, biaxial contraction of an inflated and axially extended excised vessel provides broader information, both passive and active, under more realistic conditions...
August 8, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28782386/glottis-effects-on-the-cough-clearance-process-simulated-with-a-cfd-dynamic-mesh-and-eulerian-wall-film-model
#11
Concepción Paz, Eduardo Suárez, Oscar Parga, Jesús Vence
In this study, we have reproduced the cough clearance process with an Eulerian wall film model. The simulated domain is based on realistic geometry from the literature, which has been improved by adding the glottis and epiglottis. The vocal fold movement has been included due to the dynamic mesh method, considering different abduction and adduction angles and velocities. The proposed methodology captures the deformation of the flexible tissue, considers non-Newtonian properties for the mucus, and enables us to reproduce a single cough or a cough epoch...
August 7, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28780174/a-competitive-strategy-for-atrial-and-aortic-tract-segmentation-based-on-deformable-models
#12
Pedro Morais, João L Vilaça, Sandro Queirós, Felix Bourier, Isabel Deisenhofer, João Manuel R S Tavares, Jan D'hooge
Multiple strategies have previously been described for atrial region (i.e. atrial bodies and aortic tract) segmentation. Although these techniques have proven their accuracy, inadequate results in the mid atrial walls are common, restricting their application for specific cardiac interventions. In this work, we introduce a novel competitive strategy to perform atrial region segmentation with correct delineation of the thin mid walls, and integrated it into the B-spline Explicit Active Surfaces framework. A double-stage segmentation process is used, which starts with a fast contour growing followed by a refinement stage with local descriptors...
July 27, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28773129/image-analysis-technique-for-material-behavior-evaluation-in-civil-structures
#13
Emanuela Speranzini, Roberto Marsili, Michele Moretti, Gianluca Rossi
The article presents a hybrid monitoring technique for the measurement of the deformation field. The goal is to obtain information about crack propagation in existing structures, for the purpose of monitoring their state of health. The measurement technique is based on the capture and analysis of a digital image set. Special markers were used on the surface of the structures that can be removed without damaging existing structures as the historical masonry. The digital image analysis was done using software specifically designed in Matlab to follow the tracking of the markers and determine the evolution of the deformation state...
July 8, 2017: Materials
https://www.readbyqxmd.com/read/28772634/mechanical-behavior-of-recycled-aggregate-concrete-filled-steel-tubular-columns-before-and-after-fire
#14
Wenchao Liu, Wanlin Cao, Jianwei Zhang, Ruwei Wang, Lele Ren
Recycled aggregate concrete (RAC) is an environmentally friendly building material. This paper investigates the mechanical behavior of recycled aggregate concrete filled steel tube (RACFST) columns exposed to fire. Two groups of 12 columns were designed and tested, under axial compression, before and after fire, to evaluate the degradation of bearing capacity due to fire exposure. Six specimens were subjected to axial compression tests at room temperature and the other six specimens were subjected to axial compression tests after a fire exposure...
March 9, 2017: Materials
https://www.readbyqxmd.com/read/28772624/an-experimental-study-on-the-shear-hysteresis-and-energy-dissipation-of-the-steel-frame-with-a-trapezoidal-corrugated-steel-plate
#15
Sudeok Shon, Mina Yoo, Seungjae Lee
The steel frame reinforced with steel shear wall is a lateral load resisting system and has higher strength and shear performance than the concrete shear wall system. Especially, using corrugated steel plates in these shear wall systems improves out-of-plane stiffness and flexibility in the deformation along the corrugation. In this paper, a cyclic loading test of this steel frame reinforced with trapezoidal-corrugated steel plate was performed to evaluate the structural performance. The hysteresis behavior and the energy dissipation capacity of the steel frame were also compared according to the corrugated direction of the plate...
March 6, 2017: Materials
https://www.readbyqxmd.com/read/28772556/the-effect-of-matrix-composition-on-the-deformation-and-failure-mechanisms-in-metal-matrix-syntactic-foams-during-compression
#16
Csilla Kádár, Kristián Máthis, Michal Knapek, František Chmelík
The influence of the matrix material on the deformation and failure mechanisms in metal matrix syntactic foams was investigated in this study. Samples with commercially pure Al (Al) and Al-12 wt % Si (AlSi12) eutectic aluminum matrix, reinforced by hollow ceramic spheres, were compressed at room temperature. Concurrently, the acoustic emission response and the strain field development on the surface were monitored in-situ. The results indicate that the plastic deformation of the cell walls is the governing mechanism in the early stage of straining for both types of foams...
February 17, 2017: Materials
https://www.readbyqxmd.com/read/28770124/omphalocele-and-gastroschisis-in-newborns-over-16-years-of-experience-from-a-single-clinic
#17
Shunusuke Watanabe, Tatuya Suzuki, Fujio Hara, Toshihiro Yasui, Naoko Uga, Atuki Naoe
Infants born with potentially life-threatening conditions of omphalocele and gastroschisis may require long-term hospitalization. We aimed to compare the outcomes of these two conditions occurring over a 16-year period (2001-16). It is a retrospective study of 19 newborns undergoing surgery for these two abdominal wall defects (8 patients with omphalocele and 11 cases of gastroschisis). The average birth weights for the newborns with omphaloceles and gastroschisis were 2554.5 g and 2248.6 g respectively. Associated anomalies included trisomy 18, Beckwith-Wiedemann syndrome, congenital heart disease, Meckel's diverticulum, inguinal hernias, renal deformities, limb deformities, cryptorchidism, body stalk anomalies, and closed gastroschisis...
April 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28769063/dynamics-of-levitated-objects-in-acoustic-vortex-fields
#18
Z Y Hong, J F Yin, W Zhai, N Yan, W L Wang, J Zhang, Bruce W Drinkwater
Acoustic levitation in gaseous media provides a tool to process solid and liquid materials without the presence of surfaces such as container walls and hence has been used widely in chemical analysis, high-temperature processing, drop dynamics and bioreactors. To date high-density objects can only be acoustically levitated in simple standing-wave fields. Here we demonstrate the ability of a small number of peripherally placed sources to generate acoustic vortex fields and stably levitate a wide range of liquid and solid objects...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28768517/automated-assessments-of-circumferential-strain-from-cine-cmr-correlate-with-lvef-declines-in-cancer-patients-early-after-receipt-of-cardio-toxic-chemotherapy
#19
Marie-Pierre Jolly, Jennifer H Jordan, Giselle C Meléndez, Gary R McNeal, Ralph B D'Agostino, W Gregory Hundley
BACKGROUND: In patients with cancer receiving potentially cardio-toxic chemotherapy, measurements of left ventricular (LV) circumferential or longitudinal strain are often used clinically to identify myocardial dysfunction. Using a new software algorithm, we sought to determine in individuals receiving treatment for cancer the association between automated assessments of LV mean mid-wall circumferential strain and conventional measures of LV ejection fraction (EF) both obtained from cardiovascular magnetic resonance (CMR) cine balanced steady-state free-precession (bSSFP) white-blood acquisitions...
August 2, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28763154/best-practices-in-peri-operative-management-of-patients-with-skeletal-dysplasias
#20
Klane K White, Viviana Bompadre, Michael J Goldberg, Michael B Bober, Tae-Joon Cho, Julie E Hoover-Fong, Melita Irving, William G Mackenzie, Shawn E Kamps, Cathleen Raggio, Gregory J Redding, Samantha S Spencer, Ravi Savarirayan, Mary C Theroux
Patients with skeletal dysplasia frequently require surgery. This patient population has an increased risk for peri-operative complications related to the anatomy of their upper airway, abnormalities of tracheal-bronchial morphology and function; deformity of their chest wall; abnormal mobility of their upper cervical spine; and associated issues with general health and body habitus. Utilizing evidence analysis and expert opinion, this study aims to describe best practices regarding the peri-operative management of patients with skeletal dysplasia...
August 1, 2017: American Journal of Medical Genetics. Part A
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