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https://www.readbyqxmd.com/read/27908160/correspondence-optimization-in-2d-standardized-carotid-wall-thickness-map-by-description-length-minimization-a-tool-for-increasing-reproducibility-of-3d-ultrasound-based-measurements
#1
Yimin Chen, Bernard Chiu
PURPOSE: The previously described 2D standardized vessel-wall-plus-plaque thickness (VWT) maps constructed from 3D ultrasound vessel wall measurements using an arc-length (AL) scaling approach adjusted the geometric variability of carotid arteries and has allowed for the comparisons of VWT distributions in longitudinal and cross-sectional studies. However, this mapping technique did not optimize point correspondence of the carotid arteries investigated. The potential misalignment may lead to errors in point-wise VWT comparisons...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27905564/direct-preparation-of-carbon-nanotube-intramolecular-junctions-on-structured-substrates
#2
Jianing An, Zhaoyao Zhan, Gengzhi Sun, Hari Krishna Salila Vijayalal Mohan, Jinyuan Zhou, Young-Jin Kim, Lianxi Zheng
Leveraging the unique properties of single-walled carbon nanotube (SWNT) intramolecular junctions (IMJs) in innovative nanodevices and next-generation nanoelectronics requires controllable, repeatable, and large-scale preparation, together with rapid identification and comprehensive characterization of such structures. Here we demonstrate SWNT IMJs through directly growing ultralong SWNTs on trenched substrates. It is found that the trench configurations introduce axial strain in partially suspended nanotubes, and promote bending deformation in the vicinity of the trench edges...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27900714/is-there-asymmetry-between-the-concave-and-convex-pedicles-in-adolescent-idiopathic-scoliosis-a-ct-investigation
#3
Colin M Davis, Caroline A Grant, Mark J Pearcy, Geoffrey N Askin, Robert D Labrom, Maree T Izatt, Clayton J Adam, J Paige Little
BACKGROUND: Adolescent idiopathic scoliosis is a complex three-dimensional deformity of the spine characterized by deformities in the sagittal, coronal, and axial planes. Spinal fusion using pedicle screw instrumentation is a widely used method for surgical correction in severe (coronal deformity, Cobb angle > 45°) adolescent idiopathic scoliosis curves. Understanding the anatomic difference in the pedicles of patients with adolescent idiopathic scoliosis is essential to reduce the risk of neurovascular or visceral injury through pedicle screw misplacement...
November 29, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27898445/pathologic-myopia
#4
Kyoko Ohno-Matsui
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma). The meta-analyses of the PM study group (META-PM study) made a classification system for myopic maculopathy. On the basis of this study, PM has been defined as eyes having atrophic changes equal to or more severe than diffuse atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27897200/lipid-ii-independent-antimicrobial-mechanism-of-nisin-depends-on-its-crowding-and-degree-of-oligomerization
#5
Ashutosh Prince, Padmani Sandhu, Pankaj Kumar, Eva Dash, Shingarika Sharma, Manoranjan Arakha, Suman Jha, Yusuf Akhter, Mohammed Saleem
Nisin inhibits bacterial growth by generating pores in cell membrane and interrupting cell-wall biosynthesis through specific lipid II interaction. However, the role of the hinge region and C-terminus residues of the peptide in antibacterial action of nisin is largely unknown. Here, using molecular dynamics simulations and experimental approach, we report that at high concentration regimes of nisin, interaction with phospholipids may equally deform the bacterial cell membranes even under significantly varying amounts of lipid-II...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27896349/silver-nanoparticles-a-mechanism-of-action-on-moulds
#6
Katarzyna Pietrzak, Sława Glińska, Magdalena Gapińska, Tomasz Ruman, Adriana Nowak, Egemen Aydin, Beata Gutarowska
Silver nanoparticles (AgNPs) are widely used in all branches of industry. However, their mechanisms of action towards moulds have not been studied yet. Thus we conducted this study in which we have used laser desorption/ionization time-of-flight mass spectrometry (LDI-ToF-MS) analysis to determine metabolomic changes, and microscopic analysis (transmission electron microscopy, fluorescent microscopy) to observe changes in mould cells. The AgNP treatment caused the downregulation of 162 (15 ppm) and 284 (62 ppm), and 19 (15 ppm) and 29 (62 ppm) metabolites of Aspergillus niger and Penicillium chrysogenum, respectively...
November 29, 2016: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/27894571/pre-expanded-deep-inferior-epigastric-perforator-flap
#7
REVIEW
Sharon E Monsivais, Nicholas D Webster, Stacy Wong, Michel H Saint-Cyr
The deep inferior epigastric perforator (DIEP) flap can be used to cover large defects of the proximal lower extremity, abdominal wall, perineum, vulva, and buttock. Pre-expanding DIEP flaps cause a possible delay phenomenon improving vascularity, decrease donor site morbidity, and increase the area that can be covered. Pre-expansion requires staged procedures, has risk of extrusion and infection, causes temporary contour deformity during the expansion process, and requires a longer course. Pre-expanded DIEP flaps can be a useful flap with proper patient selection and planning...
January 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/27893559/personalized-reconstruction-of-traumatic-orbital-defects-based-on-precise-three-dimensional-orientation-and-measurements-of-the-globe
#8
Li Huang, Lisong Lin, Zhihong Wang, Bin Shi, Xiaofeng Zhu, Yu Qiu, Yue Huang, Xueyuan Yu, Yunyang Liao
OBJECTIVE: The aim of the study was to precisely assess the severity of traumatic orbital defects and techniques for personalized orbital reconstruction. METHODS: A retrospective study was conducted in 97 patients with traumatic orbital defects who were treated in our hospital between July 2003 and June 2012. Pre- and postoperative spiral computed tomography scans were performed in all patients. A spatial orientation technique was used to measure the three-dimensional position of the globe and calculate the changes in the orbital volume...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27893065/histology-and-biaxial-mechanical-behavior-of-abdominal-aortic-aneurysm-tissue-samples
#9
Francesco Q Pancheri, Robert A Peattie, Nithin D Reddy, Touhid Ahamed, Wenjian Lin, Timothy D Ouellette, Mark D Iafrati, A Luis Dorfmann
Abdominal aortic aneurysms (AAA) represent permanent, localized dilations of the abdominal aorta that can be life-threatening if progressing to rupture. Evaluation of risk of rupture depends on understanding the mechanical behavior of patient AAA walls. In this project, a series of patient AAA wall tissue samples have been evaluated through a combined anamnestic, mechanical and histopathologic approach. Mechanical properties of the samples have been characterized using a novel, strain-controlled, planar biaxial testing protocol emulating the in vivo deformation of the aorta...
November 18, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27884247/machine-learning-algorithms-to-automate-morphological-and-functional-assessments-in-2d-echocardiography
#10
Sukrit Narula, Khader Shameer, Alaa Mabrouk Salem Omar, Joel T Dudley, Partho P Sengupta
BACKGROUND: Machine-learning models may aid cardiac phenotypic recognition by using features of cardiac tissue deformation. OBJECTIVES: This study investigated the diagnostic value of a machine-learning framework that incorporates speckle-tracking echocardiographic data for automated discrimination of hypertrophic cardiomyopathy (HCM) from physiological hypertrophy seen in athletes (ATH). METHODS: Expert-annotated speckle-tracking echocardiographic datasets obtained from 77 ATH and 62 HCM patients were used for developing an automated system...
November 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27883138/characterization-of-size-dependent-mechanical-properties-of-tip-growing-cells-using-a-lab-on-chip-device
#11
Chengzhi Hu, Gautam Munglani, Hannes Vogler, Tohnyui Ndinyanka Fabrice, Naveen Shamsudhin, Falk K Wittel, Christoph Ringli, Ueli Grossniklaus, Hans J Herrmann, Bradley J Nelson
Quantification of mechanical properties of tissues, living cells, and cellular components is crucial for the modeling of plant developmental processes such as mechanotransduction. Pollen tubes are tip-growing cells that provide an ideal system to study the mechanical properties at the single cell level. In this article, a lab-on-a-chip (LOC) device is developed to quantitatively measure the biomechanical properties of lily (Lilium longiflorum) pollen tubes. A single pollen tube is fixed inside the microfluidic chip at a specific orientation and subjected to compression by a soft membrane...
November 24, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27878406/diagnostic-value-of-layer-specific-global-longitudinal-strain-during-adenosine-stress-in-patients-suspected-of-coronary-artery-disease
#12
June A Ejlersen, Steen H Poulsen, Jesper Mortensen, Ole May
Speckle tracking global longitudinal strain (GLS) from dobutamine stress echocardiography (SE) predicts coronary artery disease (CAD). The diagnostic value of GLS from vasodilator SE and the additional value of layer-specific speckle tracking analysis are unclear. We explored the usefulness of layer-specific GLS and non-layer-specific strain (automated functional imaging, AFI) from adenosine SE. The included 132 patients (67% male, 62.6 (9.0) years), of which 46 (35%) had CAD defined as ≥1 stenosis ≥70% (≥50% in the left main), underwent adenosine SE and invasive coronary angiography...
November 22, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27878400/multiphoton-microscopy-observations-of-3d-elastin-and-collagen-fiber-microstructure-changes-during-pressurization-in-aortic-media
#13
Shukei Sugita, Takeo Matsumoto
Elastin and collagen fibers play important roles in the mechanical properties of aortic media. Because knowledge of local fiber structures is required for detailed analysis of blood vessel wall mechanics, we investigated 3D microstructures of elastin and collagen fibers in thoracic aortas and monitored changes during pressurization. Using multiphoton microscopy, autofluorescence images from elastin and second harmonic generation signals from collagen were acquired in media from rabbit thoracic aortas that were stretched biaxially to restore physiological dimensions...
November 22, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27877872/study-of-332-113-twinning-in-a-multilayered-ti-10mo-xfe-x-1-3-alloy-by-ecci-and-ebsd
#14
Ivan Gutierrez-Urrutia, Cheng-Lin Li, Satoshi Emura, Xiaohua Min, Koichi Tsuchiya
We have investigated the propagation of {332}<113> twins in a multilayered Ti-10Mo-xFe (x = 1-3) alloy fabricated by multi-pass hot rolling. The material contains a macroscopic Fe-graded structure (about 130 μm width) between 1 and 3 wt% Fe in the direction perpendicular to rolling. We observe strong influence of the Fe-graded structure in the twin propagation behavior. The propagation of {332}<113> twins that are nucleated in Fe-lean regions (~1 wt% Fe) is interrupted in the grain interiors at a specific Fe content, namely, about 2 wt% Fe...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27876369/multi-component-model-of-intramural-hematoma
#15
Martina Bukač, Mark Alber
A novel multi-component model is introduced for studying interaction between blood flow and deforming aortic wall with intramural hematoma (IMH). The aortic wall is simulated by a composite structure submodel representing material properties of the three main wall layers. The IMH is described by a poroelasticity submodel which takes into account both the pressure inside hematoma and its deformation. The submodel of the hematoma is fully coupled with the aortic submodel as well as with the submodel of the pulsatile blood flow...
November 15, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27876281/post-transplant-surveillance-for-acute-rejection-and-allograft-vasculopathy-by-echocardiography-usefulness-of-myocardial-velocity-and-deformation-imaging
#16
Michael Dandel, Roland Hetzer
Diagnosing and monitoring acute rejection (AR) and cardiac allograft vasculopathy (CAV) is essential for graft and transplant patient survival and, consequently, a major objective for heart transplant patient surveillance. Because functionally relevant CAV can arise and progress without clinical symptoms and sub-clinical ARs can facilitate the development of CAV, standard surveillance of AR and CAV includes routine endomyocardial biopsy (EMB) and coronary angiography (CA) screenings at pre-defined time intervals...
October 7, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27875190/combined-visualization-of-vessel-deformation-and-hemodynamics-in-cerebral-aneurysms
#17
Monique Meuschke, Samuel Voss, Oliver Beuing, Bernhard Preim, Kai Lawonn
We present the first visualization tool that combines patient-specific hemodynamics with information about the vessel wall deformation and wall thickness in cerebral aneurysms. Such aneurysms bear the risk of rupture, whereas their treatment also carries considerable risks for the patient. For the patient-specific rupture risk evaluation and treatment analysis, both morphological and hemodynamic data have to be investigated. Medical researchers emphasize the importance of analyzing correlations between wall properties such as the wall deformation and thickness, and hemodynamic attributes like the Wall Shear Stress and near-wall flow...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27873531/use-of-osteotomy-in-post-traumatic-deformity-of-frontal-sinus-anterior-wall-case-report
#18
I Němec
Post-traumatic deformity of frontal sinus anterior table can be treated in various ways. Usage of a certain type of an implant is a common method. We performed an osteotomy and subsequent reduction of the fragments to reconstruct their anatomical position. Titanium miniplates and screws were used for fixation. This case report suggests a possible use of this method in patients with more extensive frontal sinus and distinct post-traumatic deformity. No similar case manages as described in our case report was found in the literature...
2016: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/27871678/direct-numerical-simulation-of-expiratory-crackles-relationship-between-airway-closure-dynamics-and-acoustic-fluctuations
#19
Satoshi Ii, Shigeo Wada
This paper investigates the relationship between airway closure dynamics and acoustic fluctuations in expiratory crackles using direct numerical simulation. A unified mathematical model is proposed to deal with flow in an airway, elastic deformation of the airway wall, surface tension driven motion of the liquid film that lines the airway, and their acoustic fluctuations because of material compressibility. Airway closure is induced by increasing the surrounding pressure, then the source of the pressure fluctuations is measured over time...
November 11, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27865773/particulate-suspension-effect-on-peristaltically-induced-unsteady-pulsatile-flow-in-a-narrow-artery-blood-flow-model
#20
Sara I Abdelsalam, Kambiz Vafai
This work is concerned with theoretically investigating the pulsatile flow of a fluid with suspended particles in a flow driven by peristaltic waves that deform the wall of a small blood artery in the shape of traveling sinusoidal waves with constant velocity. The problem formulation in the wave frame of reference is presented and the governing equations are developed up to the second-order in terms of the asymptotic expansion of Womersley number which characterizes the unsteady effect in the wave frame. We suppose that the flow rate imposed, in this frame, is a function versus time...
November 16, 2016: Mathematical Biosciences
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