keyword
https://read.qxmd.com/read/38537034/translation-and-measurement-properties-of-the-portuguese-brazil-version-of-the-hammersmith-infant-neurological-examination-hine-br
#1
JOURNAL ARTICLE
Michelle Alexandrina Dos Santos Furtado, Hércules Ribeiro Leite, Matheus Rocha Pereira Klettenberg, Victor Alves Rodrigues, Lisiane Seguti Ferreira, Melina Rodero Marques, Isadora de Oliveira Cavalcante, Tamires Saboia Santos, Tathiana Ghisi de Souza, Ayrles Silva Gonçalves Barbosa Mendonça, Ana Cristina Resende Camargos, Kênnea Martins Almeida Ayupe
OBJECTIVE: The current study aimed to translate the Hammersmith Infant Neurological Examination (HINE) into Brazilian Portuguese and analyze the reliability of the translated version for a population of Brazilian infants. METHODS: This was a methodological study, approved by the Ethics Committee, carried out between June 2020 and May 2021. HINE is a standardized clinical neurological examination used for the early detection of cerebral palsy. The quantitative section, "neurological examination", contains 26 items scored from 0 to 3 points, divided into five categories: cranial nerve function, posture, movements, muscle tone and reflexes, and reactions...
2024: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://read.qxmd.com/read/38536170/reduced-aqueous-humor-outflow-pathway-arborization-in-childhood-glaucoma-eyes
#2
JOURNAL ARTICLE
Shikha Gupta, Xiaowei Zhang, Arnav Panigrahi, Shakha, Raymond Fang, Clemens A Strohmaier, Hao F Zhang, Robert N Weinreb, Viney Gupta, Alex S Huang
PURPOSE: To compare aqueous humor outflow (AHO) pathway patterns between eyes of childhood glaucoma patients and non-glaucomatous patients receiving cataract surgery. METHODS: Aqueous angiography was performed in childhood glaucoma eyes (n = 5) receiving glaucoma surgery and in pediatric (n = 1) and healthy adult (n = 5) eyes receiving cataract surgery. Indocyanine green (0.4%) was introduced into the anterior chamber, and AHO was imaged using an angiographic camera (SPECTRALIS HRA+OCT with Flex Module)...
March 1, 2024: Translational Vision Science & Technology
https://read.qxmd.com/read/38535617/identifying-drivers-of-cost-in-pediatric-liver-transplantation
#3
JOURNAL ARTICLE
Divya Sabapathy, Kathleen Hosek, Fong W Lam, Moreshwar S Desai, Eric Williams, John Goss, Jean L Raphael, Michelle A Lopez
BACKGROUND & AIMS: Understanding the economics of pediatric liver transplantation (LT) is central to high-value care initiatives. We examined cost and resource utilization in pediatric LT nationally to identify drivers of cost and hospital factors associated with greater total cost of care. APPROACH & RESULTS: We reviewed 3295 children (<21 y) receiving a LT from 2010-2020 in the Pediatric Health Information System to study cost, both per LT and service-line, and associated mortality, complications and resource utilization...
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38535543/prenatal-maternal-immunization-for-infant-protection-a-review-of-the-vaccines-recommended-infant-immunity-and-future-research-directions
#4
REVIEW
Elizabeth M Quincer, Lisa M Cranmer, Satoshi Kamidani
Prenatal maternal immunization is an effective tool to protect mothers and infants from poor health outcomes due to infectious diseases. We provide an overview of the rationale for the use of prenatal vaccines, discuss the immunologic environment of the maternal-fetal interface including the impact of maternal vaccines prenatally and subsequently on the infant's immune response, and review vaccines currently recommended in pregnancy and landscape for the future of maternal vaccination. This review aims to provide an understanding of the recent history and progress made in the field and highlight the importance of continued research and development into new vaccines for pregnant populations...
February 23, 2024: Pathogens
https://read.qxmd.com/read/38535515/school-medical-service-strategies-to-promote-psycho-physiological-well-being
#5
REVIEW
Francesco Tafuri, Francesca Latino
Schools represent the ideal setting for educating children about the acquisition of active lifestyles seen not only from a health point of view but also from psycho-pedagogical and social perspectives. Based on evidence from scientific literature, there is a need to include physical activity in school routines, especially in primary schools, where the habits learned by children stay with them in their later years and adulthood. With the support of the school medicine service, schools become a favorable context for planning health education sessions aimed at students, with particular reference to prevention...
March 19, 2024: Pediatric Reports
https://read.qxmd.com/read/38534508/contractile-and-genetic-characterization-of-cardiac-constructs-engineered-from-human-induced-pluripotent-stem-cells-modeling-of-tuberous-sclerosis-complex-and-the-effects-of-rapamycin
#6
JOURNAL ARTICLE
Veniamin Y Sidorov, Tatiana N Sidorova, Philip C Samson, Ronald S Reiserer, Clayton M Britt, M Diana Neely, Kevin C Ess, John P Wikswo
The implementation of three-dimensional tissue engineering concurrently with stem cell technology holds great promise for in vitro research in pharmacology and toxicology and modeling cardiac diseases, particularly for rare genetic and pediatric diseases for which animal models, immortal cell lines, and biopsy samples are unavailable. It also allows for a rapid assessment of phenotype-genotype relationships and tissue response to pharmacological manipulation. Mutations in the TSC1 and TSC2 genes lead to dysfunctional mTOR signaling and cause tuberous sclerosis complex (TSC), a genetic disorder that affects multiple organ systems, principally the brain, heart, skin, and kidneys...
February 28, 2024: Bioengineering
https://read.qxmd.com/read/38534491/reimagining-radiology-a-comprehensive-overview-of-reviews-at-the-intersection-of-mobile-and-domiciliary-radiology-over-the-last-five-years
#7
REVIEW
Graziano Lepri, Francesco Oddi, Rosario Alfio Gulino, Daniele Giansanti
(Background) Domiciliary radiology, which originated in pioneering studies in 1958, has transformed healthcare, particularly during the COVID-19 pandemic, through advancements such as miniaturization and digitization. This evolution, driven by the synergy of advanced technologies and robust data networks, reshapes the intersection of domiciliary radiology and mobile technology in healthcare delivery. (Objective) The objective of this study is to overview the reviews in this field with reference to the last five years to face the state of development and integration of this practice in the health domain...
February 24, 2024: Bioengineering
https://read.qxmd.com/read/38533999/vancomycin-auc-0-24-estimation-using-first-order-pharmacokinetic-methods-in-pediatric-patients
#8
JOURNAL ARTICLE
Hope H Brandon, David S Burgess, Katie L Wallace, Elizabeth B Autry, Katie B Olney
INTRODUCTION: The optimal dosing and monitoring of vancomycin in pediatrics is still unknown but has evolved to emphasize area under the curve over 24 h (AUC0-24 ) over minimum concentration (Cmin ) monitoring. Real-world data supporting the feasibility of two-concentration kinetics with first-order equations for the estimation of vancomycin AUC0-24 in pediatric patients are lacking. OBJECTIVES: To describe the interplay of vancomycin dose, AUC0-24 , and Cmin using first-order equations within four pediatric age groups...
March 27, 2024: Pharmacotherapy
https://read.qxmd.com/read/38533533/prediction-of-the-labrum-shape-in-patients-with-developmental-dysplasia-of-the-hip-based-on-pelvic-radiography
#9
JOURNAL ARTICLE
Xinyan Huang, Xiang Cheng, Sijie Gao, Yinxin Liu, Yuxi Su, Chuan Feng
BACKGROUND: The shape of the labrum is strongly correlated with outcomes of developmental dysplasia of the hip (DDH). Magnetic resonance imaging (MRI) is the generally preferred imaging technique for observing the labrum. PURPOSE: We aimed to find a correlation between the labrum shape and anterior-posterior (AP) pelvic measurements in children with DDH. METHODS: Preoperative AP pelvic x-ray radiographs and MRI of patients with DDH from January 2019 to December 2021 were retrospectively collected and divided into three groups by labrum shape on MRI: everted, partly inverted, and inverted...
March 27, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38533487/pediatric-corneal-transplantation-techniques-challenges-and-outcomes
#10
REVIEW
Bharat Gurnani, Kirandeep Kaur, Sameer Chaudhary, Ruminder Preet Kaur, Swatishree Nayak, Deepak Mishra, Harinikrishna Balakrishnan, Rohit Om Parkash, Arvind Kumar Morya, Amit Porwal
Pediatric corneal transplant is a highly demanding and technically challenging procedure for the cornea surgeon in today's era. These cases pose unique challenges in clinical and surgical management. The indications of pediatric corneal transplant can be therapeutic, tectonic, optical, and cosmetic. Pediatric patients undergoing corneal transplants are at a high risk of graft infection, failure, rejection, dehiscence, and amblyopia due to young age, robust immune system, increased incidence of trauma, and compliance issues...
2024: Therapeutic Advances in Ophthalmology
https://read.qxmd.com/read/38533323/equity-in-the-developmental-dysplasia-of-the-hip-ddh-diagnosis-and-treatment-a-retrospective-cohort-study-to-unravel-the-effect-of-area-deprivation-and-the-insurance-type
#11
JOURNAL ARTICLE
Samantha L Ferraro, Sarah Dance, Delara Rajabi, Ahmed Elabd, Sean Tabaie
Background Timely diagnosis of developmental dysplasia of the hip (DDH) is crucial for implementing less invasive treatment. However, socioeconomic barriers may lead to late diagnoses. The Area Deprivation Index (ADI) is an indicator of the socioeconomic challenges experienced by patients and their families. The primary objective is to investigate if the age at which DDH is diagnosed and the treatment protocol are influenced by the ADI or the insurance type. Materials and methods Using International Classification of Diseases-Tenth Edition (ICD-10) codes, newly diagnosed DDH patients (age under 10 years) from 2020 to 2023 were retrospectively identified at our pediatric tertiary center...
March 2024: Curēus
https://read.qxmd.com/read/38533093/reduction-en-masse-of-inguinal-hernia-in-a-2-month-old-male-infant
#12
Masato Kojima, Ryo Touge, Sho Kurihara, Isamu Saeki, Shinya Takahashi
Reduction en masse is the reduction of the hernial sac into the preperitoneal space, with a loop of bowel remaining trapped at the neck of the hernial sac. This complication is rare, usually associated with inguinal hernias, and is characterized by the absence of a noticeable bulge in the groin. The patient was a 2-month-old male infant and presented with a nonreducible bulge in his left groin, and incarceration of the left inguinal hernia was diagnosed. Manual reduction was performed, and the hernia bulge became less noticeable...
January 2024: European Journal of Pediatric Surgery Reports
https://read.qxmd.com/read/38532769/arthroscopic-saucerization-of-discoid-lateral-meniscus-with-meniscus-repair-as-indicated-results-in-excellent-outcomes-in-pediatric-patients-younger-than-12-years-of-age
#13
JOURNAL ARTICLE
George A Rublev, Levan Natchkebia, Vazha Gaprindashvili, Mohamed Ahmed Mohamed, Tamaz Tamazishvili, Irakli Kartozia, Mikheil Zimlitski
PURPOSE: To evaluate the experiences and outcomes of arthroscopic partial meniscectomy in symptomatic non-Wrisberg discoid lateral meniscus in children younger than 12 years old at a single center. METHODS: We retrospectively reviewed the medical records of all pediatric patients who were treated for non-Wrisberg discoid meniscus at our institute between 2013 and 2021. Patients were separated into 2 groups: Patients who underwent partial resection with saucerization (group A) or patients who underwent saucerization, tear repair, and fixation (group B)...
April 2024: Arthroscopy, sports medicine, and rehabilitation
https://read.qxmd.com/read/38532718/advances-in-hand-therapy-best-practice-in-conservative-management-of-proximal-phalangeal-fractures-in-children
#14
JOURNAL ARTICLE
Rebecca Kilty, Sarah Baxter, Marnee J McKay, Claire E Hiller
BACKGROUND: Proximal phalangeal fractures are one of the most commonly treated hand injuries in children. Conservative management of these fractures is often to splint for 5 weeks post injury, despite children presenting as clinically healed at 3 weeks post injury. Therefore, we investigated the effect of splinting for only 3 weeks in children who present with clinically healed proximal phalangeal fractures at 3 weeks compared with usual care. METHODS: Participants (n=80, aged 10...
March 27, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38532453/current-prospects-of-hereditary-adrenal-tumors-towards-better-clinical-management
#15
REVIEW
Akihiro Ohmoto, Naomi Hayashi, Shunji Takahashi, Arisa Ueki
Adrenocortical carcinoma (ACC) and pheochromocytoma/paraganglioma (PPGL) are two rare types of adrenal gland malignancies. Regarding hereditary tumors, some patients with ACC are associated with with Li-Fraumeni syndrome (LFS), and those with PPGL with multiple endocrine neoplasia type 2. Recent studies have expanded this spectrum to include other types of hereditary tumors, such as Lynch syndrome or familial adenomatous polyposis. Individuals harboring germline TP53 pathogenic variants that cause LFS have heterogeneous phenotypes depending on the respective variant type...
March 26, 2024: Hereditary Cancer in Clinical Practice
https://read.qxmd.com/read/38531715/preterm-birth-increases-cerebral-palsy-hazards-in-children-of-mothers-with-chronic-hypertension-in-pregnancy
#16
JOURNAL ARTICLE
Yi-Chien Huang, Hung-Chih Lin, Yu-Tzu Chang, Ming-Luen Tsai, Yu-Chia Chang, Lan-Wan Wang
BACKGROUND: Children of mothers with chronic-hypertension in pregnancy have high rates of preterm-birth (<37 weeks of gestation) and small-for-gestational-age (SGA), both of which are risk factors of cerebral palsy (CP). This study investigated the cumulative risks of CP in children exposed to maternal chronic-hypertension vs. other types of hypertensive-disorders-of-pregnancy (HDP), and whether preterm-birth and SGA potentiate the antenatal impact of chronic-hypertension to increase CP hazards...
March 24, 2024: Pediatrics and Neonatology
https://read.qxmd.com/read/38531473/csf-shunt-reinfection-and-malfunction-in-ecuadorian-children-with-different-reshunting-criteria-after-infection-is-just-a-shunt-after-another
#17
JOURNAL ARTICLE
Alemán-Iñiguez Juan Miguel, Alemán Iñiguez Pedro José, Hassan Noreldeen Rasha, Gonzalez Andrade Jorge
OBJECTIVE: There is no firm evidence regarding cerebrospinal fluid (CSF) shunt reimplantation after infection in the pediatric population. The purpose of this study was to compare different criteria and analyze new shunt failure. METHODS: It is a cross-sectional, retrospective, and multicenter study, in six years; the first to study patients and each infected shunt at diagnosis, reimplantation, and post-reimplantation, dividing patients into two groups: Group 1(G1): Reimplantation after negative serial CSF cultures during the antibiotic treatment; Group 2(G2): Reimplantation after negative serial pancultures following antibiotics completion; the differences were measured with: Mann Whitney and Chi-square tests; multivariate analysis and association were calculated using Odds Ratio based on logistic regression...
March 24, 2024: World Neurosurgery
https://read.qxmd.com/read/38530414/bone-flap-binding-and-transposition-a-method-for-bone-reconstruction-in-cranial-burst-fractures-and-early-stage-growing-skull-fractures
#18
JOURNAL ARTICLE
Hongbin Cao, Genrui Guo
PURPOSE: To introduce a method of cranial bone reconstruction for cranial burst fractures and early-stage growing skull fractures, named bone flap binding and transposition. METHODS: Cranial burst fractures, severe head injuries predominantly observed in infants, are characterized by widely diastatic skull fractures coupled with acute extracranial cerebral herniation beneath an intact scalp through ruptured dura mater. These injuries can develop into growing skull fractures...
March 26, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://read.qxmd.com/read/38529849/paediatric-steatotic-liver-disease-has-unique-characteristics-%C3%A2-a-multisociety-statement-endorsing-the-new-nomenclature
#19
JOURNAL ARTICLE
Pietro Vajro
Nonalcoholic fatty liver disease (NAFLD) has been a commonly used term and diagnosis in paediatric hepatology, gastroenterology, and endocrinology clinics for over 30 years. A multisociety Delphi process has determined a new name "Steatotic Liver Disease" (SLD) as the overarching term for disorders associated with hepatic lipid accumulation. Our Societies give our support to steatotic liver disease as the best overarching term for use in our communities. Metabolic dysfunction-associated steatotic liver disease (MASLD) overcomes many of the shortcomings of the name NAFLD...
March 26, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38529810/medulloblastoma-in-a-child-with-osteoma-cutis%C3%A2-a-rare-association-due-to-loss-of-gnas-expression
#20
Jananie Suntharesan, Ekaterina Lyulcheva-Bennett, Rachel Hart, Barry Pizer, James Hayden, Renuka Ramakrishnan
OBJECTIVES: Inactivating GNAS mutations result in varied phenotypes depending on parental origin. Maternally inherited mutations typically lead to hormone resistance and Albright's hereditary osteodystrophy (AHO), characterised by short stature, round facies, brachydactyly and subcutaneous ossifications. Paternal inheritance presents with features of AHO or ectopic ossification without hormone resistance. This report describes the case of a child with osteoma cutis and medulloblastoma...
March 27, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
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