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https://www.readbyqxmd.com/read/28230965/fluorine-functionalized-graphene-quantum-dots-as-inhibitor-against-hiapp-amyloid-aggregation
#1
Maryam Yousaf, Huan Huang, Ping Li, Chen Wang, Yanlian Yang
Fibrillar deposits of the human islet amyloid polypeptide (hIAPP) is considered as a root of Type II diabetes mellitus. Fluorinated graphene quantum dots (FGQDs) are new carbon nanomaterials with unique physicochemical properties containing highly electronegative F atoms. Herein we report a single step synthesis method of FGQDs with an inhibitory effect on aggregation and cytotoxicity of hIAPP in vitro. Highly fluorescent and water dispersible FGQDs, less than 3 nm in size were synthesized by the microwave-assisted hydrothermal method...
February 23, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28230569/procedure-oriented-torsional-anatomy-of-the-hand-for-spasticity-injection
#2
Joslyn John, John Cianca, Faye Chiou-Tan, Sindhu Pandit, Erin Furr-Stimming, Katherine H Taber
OBJECTIVES: To provide musculoskeletal ultrasound (MSKUS) images of hand anatomy in the position of hemiparetic flexion as a reference for spasticity injections. After a stroke, spasticity can result in anatomic distortion of the hand. Spasticity may require treatment with botulinum toxin or phenol injections. Anatomic distortion may decrease the accuracy of injections. Standard anatomic references are of limited utility because they are not in this spastic hemiparetic position. There presently is no anatomic reference in the literature for these spastic postures...
February 23, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28230538/interrogating-surface-state-of-isolated-and-agglomerated-pbs-quantum-dots-with-solvent-induced-stress
#3
Pin-Hao Sher, Juen-Kai Wang
Applications of quantum dot (QD) are often obstructed by its associated surface electronic states that quench photoluminescence (PL) and hinder charge transport. Their origins are still largely stymied owing to lacking means to regulate their presence. Dispersing PbS QDs in toluene, we show that varying solvent temperature offers an opportunity to modulate their surface electronic state. A comprehensive energy-transfer model explains all anomalous temperature-dependent behaviors of absorption and PL, explicitly revealing PL quenching dynamics of isolated QDs due to induced surface state by imposed solvent stress to their surface ligands...
February 23, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28230392/two-roads-diverged-distinct-mechanisms-of-attentional-bias-differentially-predict-negative-affect-and-persistent-negative-thought
#4
Sandersan Onie, Steven B Most
Attentional biases to threatening stimuli have been implicated in various emotional disorders. Theoretical approaches often carry the implicit assumption that various attentional bias measures tap into the same underlying construct, but attention itself is not a unitary mechanism. Most attentional bias tasks-such as the dot probe (DP)-index spatial attention, neglecting other potential attention mechanisms. We compared the DP with emotion-induced blindness (EIB), which appears to be mechanistically distinct, and examined the degree to which these tasks predicted (a) negative affect, (b) persistent negative thought (i...
February 23, 2017: Emotion
https://www.readbyqxmd.com/read/28227786/a-tunable-digital-ishihara-plate-for-pre-school-aged-children
#5
Orazio Gambino, Ester Minafo, Roberto Pirrone, Edoardo Ardizzone, Orazio Gambino, Ester Minafo, Roberto Pirrone, Edoardo Ardizzone, Ester Minafo, Edoardo Ardizzone, Roberto Pirrone, Orazio Gambino
Colors play a fundamental role for children, both in the everyday life and in education. They recognize the surrounding world, and play games making a large use of colors. They learn letters and numbers by means of colors. As a consequence, early diagnosis of color blindness is an crucial to support an individual affected by this visual perception alteration at the initial phase of his/her life. The diagnosis of red-green color deficiencies (protanopia or deuteranopia) is commonly accomplished by means of the Ishihara test, which consists of plates showing dots with different sizes where some of them compose numbers within a gamut of colors while the ones composing the background have different colors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226439/optical-imaging-of-functional-connectivity-at-the-bedside
#6
Joseph P Culver, Karla M Bergonzi, Adam E Eggebrecht, Andrew K Fishell, Jin-Moo Lee, Joseph P Culver, Karla M Bergonzi, Adam E Eggebrecht, Andrew K Fishell, Jin-Moo Lee, Andrew K Fishell, Joseph P Culver, Jin-Moo Lee, Karla M Bergonzi, Adam E Eggebrecht
High-density imaging arrays have improved the image quality of diffuse optical tomography (HD-DOT) methods for mapping brain functions. Development of resting state measures of functional connectivity provides a brain assay logistically compatible with bedside imaging in the clinic. In this paper we review these advances and demonstrate the sensitivity of HD-DOT to acute ischemic stroke.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225584/preferential-alignment-of-incommensurate-block-copolymer-dot-arrays-forming-moir%C3%A3-superstructures
#7
Cong Jin, Brian C Olsen, Erik J Luber, Jillian M Buriak
Block copolymer (BCP) self-assembly is of great interest as a cost-effective method for large-scale, high-resolution nanopattern fabrication. Directed self-assembly can induce long-range order and registration, reduce defect-density, and enable access to patterns of higher complexity. Here we demonstrate preferential orientation of two incommensurate BCP dot arrays. A bottom layer of hexagonal silica dots is prepared via typical self-assembly from a PS-b-PDMS block copolymer. Self-assembly of a second, or top, layer of a different a PS-b-PDMS block copolymer that forms a hexagonal dot pattern with different periodicity, results in a predictable Moiré superstructure...
February 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28225213/a-dual-organic-transistor-based-tactile-perception-system-with-signal-processing-functionality
#8
Yaping Zang, Hongguang Shen, Dazhen Huang, Chong-An Di, Daoben Zhu
Organic-device-based tactile-perception systems can open up new opportunities for the next generation of intelligent products. To meet the critical requirements of artificial perception systems, the efficient construction of organic smart elements with integrated sensing and signal processing functionalities is highly desired, but remains a challenge. This study presents a dual-organic-transistor-based tactile-perception element (DOT-TPE) with biomimetic functionality by the construction of organic synaptic transistors with integrated sensing transistors...
February 22, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28224970/an-improved-p300-pattern-in-bci-to-catch-user-s-attention
#9
Jing Jin, Hanhan Zhang, Daly Ian, Xingyu Wang, Andrzej Cichocki
OBJECTIVE: Brain-computer interfaces (BCIs) can help patients who have lost control over most muscles but are still conscious and able to communicate or interact with the environment. One of the most popular types of BCI is the P300-based BCI. With this BCI, users are asked to count the number of appearances of target stimuli in an experiment. To date, the majority of visual P300-based BCI systems developed have used the same character or picture as the target for every stimulus presentation, which can bore users...
February 22, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28224905/emerging-trends-in-biosensing-using-stripping-voltammetric-detection-of-metal-containing-nanolabels-a-review
#10
REVIEW
Christos Kokkinos, Anastasios Economou
Over the last years, nanomaterials have found many applications in the development of electrochemical biosensors. Among other functions, metal nanoparticles (NPs) and quantum dots (QDs) (semiconducting nanocrystals composed of metal salts) are increasingly being used as voltammetric labels in affinity biosensing. Labeling is based on the attachment of the label(s) on the target biomolecules or on a biorecognition reporting probe. After an appropriate specific affinity interaction between the target and the reporting probe, the metallic nanolabels are converted to the respective cations which are quantified by a voltammetric technique...
April 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28224423/prognostic-significance-of-autophagy-related-proteins-expression-in-resected-human-gastric-adenocarcinoma
#11
Bing Qu, Lei Yao, Hua-Ling Ma, Hong-Lei Chen, Zhi Zhang, Jiang Xie
Gastric adenocarcinoma (GC) is one of the most common malignancies in the world and one of the most frequent causes of cancer-related death. Autophagy is a highly regulated catabolic pathway responsible for the degradation of long-lived proteins and damaged intracellular organelles. However, the mechanism and guiding significance of autophagy in the development and progression of GC have remained to be elucidated. This study aimed to explore the clinicopathological significances and prognostic values of autophagy-related proteins AMBRA1 and Beclin-1 in GC...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28223743/dermoscopic-features-of-small-medium-and-large-sized-congenital-melanocytic-nevi
#12
Fatma Pelin Cengiz, Nazan Emiroglu, Dilek Biyik Ozkaya, Ozlem Su, Nahide Onsun
BACKGROUND: Congenital melanocytic nevi (CMN) are present at birth. It is well known that the presence of large-sized congenital nevus in early life could predict a major risk of developing melanoma. OBJECTIVE: To investigate the clinical and dermoscopic features of the CMN, to search for and highlight any differences between small-sized, medium-sized, large-sized CMN. METHODS: A nonrandomized observational study was performed. A total of 108 melanocytic nevi were analysed by clinical and dermoscopic examination...
February 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28222367/a-novel-turn-on-fluorescent-strategy-for-sensing-ascorbic-acid-using-graphene-quantum-dots-as-fluorescent-probe
#13
Hua Liu, Weidan Na, Ziping Liu, Xueqian Chen, Xingguang Su
In this paper, a facile and rapid fluorescence turn-on assay for fluorescent detection of ascorbic acid (AA) was developed by using the orange emission graphene quantum dots (GQDs). In the presence of horse radish peroxidase (HRP) and hydrogen peroxide (H2O2), catechol can be oxidized by hydroxyl radicals and converted to o-benzoquinone, which can significantly quench the fluorescence of GQDs. However, when AA present in the system, it can consume part of H2O2 and hydroxyl radicals to inhibit the generation of o-benzoquinone, resulting in fluorescence recovery...
February 4, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28222361/biological-and-catalytic-applications-of-green-synthesized-fluorescent-n-doped-carbon-dots-using-hylocereus-undatus
#14
Velusamy Arul, Thomas Nesakumar Jebakumar Immanuel Edison, Yong Rok Lee, Mathur Gopalakrishnan Sethuraman
In this work, a simple hydrothermal route for the synthesis of fluorescent nitrogen doped carbon dots (N-CDs) is reported. The Hylocereus undatus (H. undatus) extract and aqueous ammonia are used as carbon and nitrogen source, respectively. The optical properties of synthesized N-CDs are analyzed using UV-Visible (UV-Vis) and fluorescence spectroscopy. The surface morphology, elemental composition, crystallinity and functional groups present in the N-CDs are examined using high resolution transmission electron microscopy (HR-TEM) with energy dispersive spectroscopy (EDS), selected area electron diffraction (SAED), X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) spectroscopy, respectively...
February 13, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28222116/the-role-of-short-term-memory-and-visuo-spatial-skills-in-numerical-magnitude-processing-evidence-from-turner-syndrome
#15
Lucie Attout, Marie-Pascale Noël, Marie-Cécile Nassogne, Laurence Rousselle
Most studies on magnitude representation have focused on the visual modality with no possibility of disentangling the influence of visuo-spatial skills and short-term memory (STM) abilities on quantification processes. This study examines this issue in patients with Turner syndrome (TS), a genetic condition characterized by a specific cognitive profile frequently associating poor mathematical achievement, low spatial skills and reduced STM abilities. In order to identify the influence of visuo-spatial and STM processing on numerical magnitude abilities, twenty female participants with TS and twenty control female participants matched for verbal IQ and education level were administered a series of magnitude comparison tasks...
2017: PloS One
https://www.readbyqxmd.com/read/28222048/comparison-of-running-economy-values-while-wearing-no-shoes-minimal-shoes-and-normal-running-shoes
#16
Robbie G Cochrum, Ryan T Connors, John M Coons, Dana K Fuller, Don W Morgan, Jennifer L Caputo
Cochrum, RG, Connors, RT, Coons, JM, Fuller, DK, Morgan, DW, and Caputo, JL. Comparison of running economy values while wearing no shoes, minimal shoes, and normal running shoes. J Strength Cond Res 31(3): 595-601, 2017-The purpose of this study was to quantify differences in running economy (RE) at 50 and 70% of each subject's velocity at V[Combining Dot Above]O2max (vV[Combining Dot Above]O2max) across barefoot and 2 mass, stack height, and heel-to-toe-drop controlled footwear conditions (minimal shoes and normal running shoes) in 9 recreational distance runners (mean age 26...
March 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28222047/coherent-control-of-optical-absorption-and-the-energy-transfer-pathway-of-an-infrared-quantum-dot-hybridized-with-a-vo2-nanoparticle
#17
Ali Hatef, Naser Zamani, William Johnston
We systematically investigate the optical response of a semiconductor quantum dot (QD) hybridized with a vanadium dioxide nanoparticle (VO2NP) in the infrared (IR) region. The VO2NP features a semiconductor to metal phase change characteristic below and above a critical temperature that leads to an abrupt change in the particle's optical properties. This feature means that the QD-VO2NP hybrid system can support the coherent coupling of exciton-polaritons and exciton-plasmon polaritons in the semiconductor and metal phases of the VO2NP, respectively...
February 21, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28221785/homogeneous-synthesis-and-electroluminescence-device-of-highly-luminescent-cspbbr3-perovskite-nanocrystals
#18
Song Wei, Yanchun Yang, Xiaojiao Kang, Lan Wang, Lijian Huang, Daocheng Pan
Highly luminescent CsPbBr3 perovskite nanocrystals (PNCs) are homogeneously synthesized by mixing toluene solutions of PbBr2 and cesium oleate at room temperature in open air. We found that PbBr2 can be easily dissolved in nonpolar toluene in the presence of tetraoctylammonium bromide, which allows us to homogeneously prepare CsPbBr3 perovskite quantum dots and prevents the use of harmful polar organic solvents, such as N,N-dimethylformamide, dimethyl sulfoxide, and N-methyl-2-pyrrolidone. Additionally, this method can be extended to synthesize highly luminescent CH3NH3PbBr3 perovskite quantum dots...
February 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28221761/ultrasmall-superbright-neodymium-upconversion-nanoparticles-via-energy-migration-manipulation-and-lattice-modification-808-nm-activated-drug-release
#19
Yan Zhang, Zhongzheng Yu, Jingqiu Li, Yanxiao Ao, Jingwen Xue, Zhiping Zeng, Xiangliang Yang, Timothy Thatt Yang Tan
Nd(3+)-sensitized upconversion nanoparticles are amongst the most promising emerging fluorescent nanotransducers. They are activated by 808 nm irradiation, which features merits such as limited tissue overheating and deeper penetration depth, hence attractive for diagnostic and therapeutic applications. Recent studies indicate that ultrasmall nanoparticles (<10 nm) are potentially more suitable for clinical application due to their favorable biodistribution and safety profiles. However, upconversion nanoparticles in the sub-10 nm range suffer from poor luminescence due to their ultrasmall size and greater proportion of lattice defects...
February 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28221751/molecular-engineering-and-design-of-semiconducting-polymer-dots-with-narrow-band-near-infrared-emission-for-in-vivo-biological-imaging
#20
Chi-Shiang Ke, Chia-Chia Fang, Jia-Ying Yan, Po-Jung Tseng, Joseph R Pyle, Chuan-Pin Chen, Shu-Yi Lin, Jixin Chen, Xuanjun Zhang, Yang-Hsiang Chan
This article describes the design and synthesis of donor-bridge-acceptor-based semiconducting polymer dots (Pdots) that exhibit narrow-band emissions, ultrahigh brightness, and large Stokes shifts in the near-infrared (NIR) region. We systematically investigated the effect of π-bridges on the fluorescence quantum yields of the donor-bridge-acceptor-based Pdots. The Pdots could be excited by a 488 or 532 nm laser and have a high fluorescence quantum yield of 33% with a Stokes shift of more than 200 nm. The emission full width at half-maximum of the Pdots can be as narrow as 29 nm, about 2...
February 23, 2017: ACS Nano
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