Francesca Veronesi, Gianluca Giavaresi, Milena Fini, Giovanni Longo, Caterina Alexandra Ioannidu, Anna Scotto d'Abusco, Fabiana Superti, Gianluca Panzini, Carlo Misiano, Alberto Palattella, Paolo Selleri, Nicola Di Girolamo, Viola Garbarino, Laura Politi, Roberto Scandurra
Titanium implants coated with a 500nm nanostructured layer, deposited by the Ion Plating Plasma Assisted (IPPA) technology, composed of 60% graphitic carbon, 25% titanium oxides and 15% titanium carbide were implanted into rabbit femurs whilst into the controlateral femurs uncoated titanium implants were inserted as control. At four time points the animals were injected with calcein green, xylenol orange, oxytetracycline and alizarin. After 2, 4 and 8weeks femurs were removed and processed for histology and static and dynamic histomorphometry for undecalcified bone processing into methylmethacrylate, sectioned, thinned, polished and stained with Toluidine blue and Fast green...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications