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https://www.readbyqxmd.com/read/29471106/historical-and-contemporary-features-of-infections-due-to-clostridium-novyi
#1
REVIEW
David M Aronoff, Powel H Kazanjian
Clostridium novyi is an anaerobic bacterium that resides in the soil in nature and that may cause severe clinical infections in humans. It is named after Frederick Novy, who incidentally discovered the anaerobic organism responsible for septicemia in rabbits. In this paper, we explore the circumstances surrounding the identification of the organism. In particular, we address who Novy was and what he was trying to do when he first described the organism in the 1890s. We then address what is known about the biological features of the organism today, as well as the clinical syndromes that are now recognized to be associated with the microbe...
February 19, 2018: Anaerobe
https://www.readbyqxmd.com/read/29462274/increased-mrsa-septicemia-may-be-due-to-illicit-intravenous-drug-use-in-the-south
#2
Forest W Arnold, Leslie A Beavin
No abstract text is available yet for this article.
February 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29459888/genetic-separation-of-listeria-monocytogenes-causing-central-nervous-system-infections-in-animals
#3
Lisandra Aguilar-Bultet, Pamela Nicholson, Lorenz Rychener, Margaux Dreyer, Bulent Gözel, Francesco C Origgi, Anna Oevermann, Joachim Frey, Laurent Falquet
Listeria monocytogenes is a foodborne pathogen that causes abortion, septicemia, gastroenteritis and central nervous system (CNS) infections in ruminants and humans. L. monocytogenes strains mainly belong to two distinct phylogenetic groups, named lineages I and II. In general, clinical cases in humans and animals, in particular CNS infections, are caused by lineage I strains, while most of the environmental and food strains belong to lineage II. Little is known about why lineage I is more virulent than lineage II, even though various molecular factors and mechanisms associated with pathogenesis are known...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29456951/endoscopic-endo-nasal-trans-sphenoidal-excision-of-pituitary-tumors-an-institutional-experience
#4
Amardeep Singh, Sarvpreet Singh Grewal, Navneet Kumar
To analyze the clinical presentation, management and outcomes of patients with pituitary adenoma treated by Endoscopic Endo-nasal Trans-sphenoidal (EETS) excision. Study was conducted on the basis of medical records of 14 patients who had undergone EETS excision of pituitary adenomas. The data obtained was assessed for demographic and clinical characteristics, radiographic features and post-operative outcomes. Study included 10 males and 4 females. Mean age of patients was 46.43 years (range 16-70 Years). Most common presentation was diminished vision reported in 79% patients...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29455840/cardiac-surgery-outcomes-in-patients-with-chronic-lymphocytic-leukemia
#5
Yuanjia Zhu, Andrew J Toth, Ashley M Lowry, Eugene H Blackstone, Brian T Hill, Stephanie L Mick
BACKGROUND: Surgical outcomes of patients with chronic lymphocytic leukemia (CLL) undergoing cardiac surgery are limited. Our objectives were to investigate hospital morbidity and mortality after open cardiac surgery in CLL versus non-CLL patients. METHODS: From May 1995 to May 2015, 157 patients with CLL and 55,917 without and older than 47 years underwent elective cardiac surgery at Cleveland Clinic. By Rai criteria, 79 CLL patients (56%) were low risk (class 0), 13 (9...
February 15, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29455334/septicemia-from-lactobacillus-rhamnosus-gg-from-a-probiotic-enriched-yogurt-in-a-patient-with-autologous-stem-cell-transplantation
#6
Satoshi Koyama, Hiroyuki Fujita, Takeshi Shimosato, Aki Kamijo, Yasufumi Ishiyama, Eri Yamamoto, Yoshimi Ishii, Yukako Hattori, Maki Hagihara, Etsuko Yamazaki, Naoto Tomita, Hideaki Nakajima
Probiotic-rich foods are consumed without much restriction. We report here, a case of septic shock caused by yogurt derived Lactobacillus species in a 54-year-old male patient with acute promyelocytic leukemia, in second complete remission, and who was an autologous stem cell transplantation recipient. He received high dose chemotherapy and autologous peripheral blood stem cell transplantation. He ingested commercially available probiotic-enriched yogurt because of severe diarrhea. One week later, he developed septic shock, and the pathogen was determined by strain-specific PCR analysis as Lactobacillus rhamnosus GG (ATCC 53103), which was found to be identical with the strain in the yogurt he consumed...
February 17, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29449397/draft-genome-sequence-of-listeria-monocytogenes-strain-ciims-ph-1-a-serovar-4b-isolate-from-infant-septicemia
#7
Pooja M Kishnani, Ankita A Tiwari, Vikas Gautam, Megha Sharma, Sukhadeo B Barbuddhe, Swapnil P Doijad, Trinad Chakraborty, Amit R Nayak, Nidhi M Bhartiya, Hatim F Daginawala, Lokendra R Singh, Rajpal S Kashyap
We report here the draft genome sequence of Listeria monocytogenes CIIMS-PH-1, an isolate obtained from a 16-day-old infant with septicemia. The draft genome of CIIMS-PH-1 consisted of 2,939,183 bp and is a member of sequence type 308, clonal complex 1, and lineage I.
February 15, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29449396/draft-genome-sequence-of-a-pathogenic-vibrio-vulnificus-strain-isolated-in-brazil
#8
Monique Ribeiro Tiba-Casas, Eneida Gonçalves Lemes-Marques, Elisabete Aparecida Almeida, Flávia Barrosa Soares, Carlos Henrique Camargo
We describe the draft genome sequence of the clinical Vibrio vulnificus strain 03_7315, isolated in 2016 from the blood of a diabetic patient who died of septicemia after ingestion of seafood. The draft genome, with 4,755,588 bp covering two chromosomes, presented 4,434 genes, 4,213 coding sequences, and 117 pseudogenes.
February 15, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29444101/development-and-characterization-of-two-cell-lines-from-gills-of-atlantic-salmon
#9
Mona C Gjessing, Maria Aamelfot, William N Batts, Sylvie L Benestad, Ole B Dale, Even Thoen, Simon C Weli, James R Winton
Gill disease in Atlantic salmon, Salmo salar L., causes big losses in the salmon farming industry. Until now, tools to cultivate microorganisms causing gill disease and models to study the gill responses have been lacking. Here we describe the establishment and characterization of two cell lines from the gills of Atlantic salmon. Atlantic salmon gill cell ASG-10 consisted of cells staining for cytokeratin and e-cadherin and with desmosomes as seen by transmission electron microscopy suggesting the cells to be of epithelial origin...
2018: PloS One
https://www.readbyqxmd.com/read/29438867/evaluation-of-the-microscopic-distribution-of-florfenicol-in-feed-pellets-for-salmon-by-fourier-transform-infrared-imaging-and-multivariate-analysis
#10
Camila Y Bastidas, Carlos von Plessing, José Troncoso, Rosario Del P Castillo
Fourier Transform infrared imaging and multivariate analysis were used to identify, at the microscopic level, the presence of florfenicol (FF), a heavily-used antibiotic in the salmon industry, supplied to fishes in feed pellets for the treatment of salmonid rickettsial septicemia (SRS). The FF distribution was evaluated using Principal Component Analysis (PCA) and Augmented Multivariate Curve Resolution with Alternating Least Squares (augmented MCR-ALS) on the spectra obtained from images with pixel sizes of 6...
February 7, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29436420/chtyper-a-web-tool-for-subtyping-of-extraintestinal-pathogenic-escherichia-coli-based-on-the-fumc-and-fimh-alleles
#11
Louise Roer, Thor Bech Johannesen, Frank Hansen, Marc Stegger, Veronika Tchesnokova, Evgeni Sokurenko, Natasha Garibay, Rosa Allesøe, Martin C F Thomsen, Ole Lund, Henrik Hasman, Anette M Hammerum
Escherichia coli can cause a variety of extra-intestinal infections, such as urinary tract infection, meningitis, peritonitis and septicemia.….
February 7, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29429778/hydrocephalus-in-pediatric-traumatic-brain-injury-national-incidence-risk-factors-and-outcomes-in-124-444-hospitalized-patients
#12
Kavelin Rumalla, Vijay Letchuman, Kyle A Smith, Paul M Arnold
BACKGROUND: Hydrocephalus is a life-threatening sequela of traumatic brain injury (TBI) with poorly defined epidemiology in children. Here, we report the national incidence, risk factors, and outcomes associated with post-traumatic hydrocephalus (PTH). METHODS: The Kids Inpatient Database (2003, 2006, 2009, 2012) was queried using the International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes to identify all patients (age 0 to 20) with TBI (850...
December 11, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29429482/enteric-coronavirus-infection-in-adult-horses
#13
N Pusterla, R Vin, C M Leutenegger, L D Mittel, T J Divers
A new enteric virus of adult horses, equine coronavirus (ECoV), has recently been recognized. It is associated with fever, lethargy, anorexia, and less frequently, colic and diarrhea. This enteric virus is transmitted via the feco-oral route and horses become infected by ingesting fecally contaminated feed and water. Various outbreaks have been reported since 2010 from Japan, Europe and the USA. While the clinical signs are fairly non-specific, lymphopenia and neutropenia are often seen. Specific diagnosis is made by the detection of ECoV in feces by either quantitative real-time PCR, electron microscopy or antigen-capture ELISA...
January 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29428154/neonatal-infection-in-children-with-cerebral-palsy-a-registry-based-cohort-study
#14
Anne-Sophie Smilga, Jarred Garfinkle, Pamela Ng, John Andersen, David Buckley, Darcy Fehlings, Adam Kirton, Ellen Wood, Esias van Rensburg, Michael Shevell, Maryam Oskoui
BACKGROUND: The goal of this study was to explore the association between neonatal infection and outcomes in children with cerebral palsy. METHODS: We conducted a retrospective cohort study using the Canadian CP Registry. Neonatal infection was defined as meeting one of the following criteria: (1) septicemia, (2) septic shock, or (3) administration of antibiotics for ≥10 days. Phenotypic profiles of children with cerebral palsy with and without an antecedent neonatal infection were compared...
December 13, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29423970/autoinducer2-affects-trimethoprim-sulfamethoxazole-susceptibility-in-avian-pathogenic-escherichia-coli-dependent-on-the-folate-synthesis-associate-pathway
#15
Lumin Yu, Wenchang Li, Ming Zhang, Yunmei Cui, Xiaolin Chen, Jingtian Ni, Li Yu, Fei Shang, Ting Xue
Avian pathogenic Escherichia coli (APEC) causes airsacculitis, polyserositis, septicemia, and other mainly extraintestinal diseases in chickens, ducks, geese, pigeons, and other avian species, and is responsible for great economic losses in the avian industry. The autoinducer 2 (AI-2) quorum sensing system is widely present in many species of gram-negative and gram-positive bacteria and has been proposed to be involved in interspecies communication. In clinical APEC strains, whether or not AI-2 affects the expression of antibiotic-related genes has not been reported...
February 9, 2018: MicrobiologyOpen
https://www.readbyqxmd.com/read/29422727/pattern-and-outcome-of-obstetric-admissions-into-the-intensive-care-unit-of-a-southeast-nigerian-hospital
#16
Benjamin Chukwuma Ozumba, Leonard Ogbonna Ajah, Vitus Okwuchukwu Obi, Uche Anthony Umeh, Joseph Tochukwu Enebe, Kingsley Chukwu Obioha
Background and Aims: Although pregnancy and labor are considered physiological processes, the potential for catastrophic complications is constant and may develop rapidly. There is growing evidence that admission of high-risk patients into the Intensive Care Unit (ICU) is associated with a reduction in maternal mortality. This study was aimed at reviewing all obstetric patients admitted into the ICU. Materials and Methods: This was a retrospective study of all obstetric patients who were admitted into the ICU between January 1, 2012, and December 31, 2013...
January 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29420161/economic-evaluation-of-pneumococcal-vaccines-for-adults-aged-over-50-years-in-belgium
#17
Lander Willem, Adriaan Blommaert, Germaine Hanquet, Nancy Thiry, Joke Bilcke, Heidi Theeten, Jan Verhaegen, Herman Goossens, Philippe Beutels
Streptococcus pneumoniae causes a high disease burden including pneumonia, meningitis and septicemia. Both a polysaccharide vaccine targeting 23 serotypes (PPV23) and a 13-valent conjugate vaccine (PCV13) are indicated for persons aged over 50 years. We developed and parameterized a static multi-cohort model to estimate the incremental cost-effectiveness and budget-impact of these vaccines at different uptake levels. Using three different vaccine efficacy scenarios regarding non-invasive pneumococcal pneumonia and extensive uni- and multivariate sensitivity analyses, we found a strong preference for PPV23 over PCV13 in all age groups at willingness to pay levels below €300 000 per quality adjusted life year (QALY)...
February 8, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29413343/clinical-and-economic-burden-of-hospitalizations-with-registration-of-penicillin-allergy
#18
Bernardo Sousa-Pinto, António Cardoso-Fernandes, Luís Araújo, João Almeida Fonseca, Alberto Freitas, Luís Delgado
BACKGROUND: Penicillin allergy is commonly reported, but only a minority of claimants has a confirmed diagnosis. Nevertheless, patients labeled as having penicillin allergy are treated with second-line antibiotics, which are more expensive and less effective, possibly increasing the risk of drug-resistant infections. OBJECTIVE: To compare hospitalizations with and without registration of penicillin allergy concerning their morbidity and hospital resource use. METHODS: We analyzed a national administrative database containing a registration of all Portuguese hospitalizations from 2000 to 2014...
February 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29406776/genotypic-characterization-of-arcobacter-spp-isolated-from-chicken-meat-in-brazil
#19
Maria Gabriela Xavier de Oliveira, Vasco Túlio de Moura Gomes, Marcos Paulo Vieira Cunha, Luisa Zanolli Moreno, Andrea Micke Moreno, Terezinha Knöbl
Arcobacter butzleri, Arcobacter cryaerophilus, and Arcobacter skirrowii are Gram-negative pathogenic microorganisms that cause watery diarrhea and septicemia in humans. The aims of this study were to detect the presence of Arcobacter spp. in chicken meat from butcher shops in São Paulo (Brazil) and to verify their virulence genes and genotypic profiles. A total of 300 chicken cuts were analyzed. The results show the presence of Arcobacter spp. in 18.3% of samples, which were identified as A. butzleri (63.6%) and A...
February 6, 2018: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29402745/design-synthesis-and-antibacterial-evaluation-of-honokiol-derivatives
#20
Bo Wu, Su-Hong Fu, Huan Tang, Kai Chen, Qiang Zhang, Ai-Hua Peng, Hao-Yu Ye, Xing-Jun Cheng, Mao Lian, Zhen-Ling Wang, Li-Juan Chen
Staphylococcus aureus is a major and dangerous human pathogen that causes a range of clinical manifestations of varying severity, and is the most commonly isolated pathogen in the setting of skin and soft tissue infections, pneumonia, suppurative arthritis, endovascular infections, foreign-body associated infections, septicemia, osteomyelitis, and toxic shocksyndrome. Honokiol, a pharmacologically active natural compound derived from the bark of Magnolia officinalis, has antibacterial activity against Staphylococcus aureus which provides a great inspiration for the discovery of potential antibacterial agents...
June 8, 2017: Bioorganic & Medicinal Chemistry Letters
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