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Septicemia

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https://www.readbyqxmd.com/read/28921168/chromosomal-abnormalities-affect-the-surgical-outcome-in-infants-with-hypoplastic-left-heart-syndrome-a-large-cohort-analysis
#1
Dala Zakaria, Xinyu Tang, Rupal Bhakta, Nahed O ElHassan, Parthak Prodhan
Patients with hypoplastic left heart syndrome (HLHS) can have associated genetic abnormalities. This study evaluated the incidence of genetic abnormalities among infants with HLHS and the short-term outcomes of this population during the first hospitalization. This is a retrospective analysis of the multi-center Pediatric Heath Information System database of infants with HLHS who underwent Stage I Norwood, Hybrid, or heart transplant during their first hospitalization from 2004 through 2013. We compared clinical data between infants with and without genetic abnormality, among the three most common chromosomal abnormalities, and between survivors and non-survivors...
September 18, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28920017/esophageal-atresia-with-tracheo-esophageal-fistula-presenting-beyond-7-days
#2
Nilesh Nagdeve, Mohini Sukhdeve, Tushar Thakre, Suresh Morey
AIM: To describe our experience of neonates with esophageal atresia with tracheo-esophageal fistula (EA with TEF) who presented after a week. DESIGN: Retrospective study of the patients of EA with TEF who presented after a week. STUDY SETTING: Department of Pediatric Surgery, Government Medical College Nagpur. Study Duration: Eight years. MATERIALS AND METHODS: Demographic information, hematological, biochemical and radiological data were obtained from the patients' medical records...
July 2017: Journal of Neonatal Surgery
https://www.readbyqxmd.com/read/28918753/neonatal-intestinal-obstruction-associated-with-situs-inversus-totalis-two-case-reports-and-a-review-of-the-literature
#3
Rahul Gupta, Varsha Soni, Prakash Devidas Valse, Ram Babu Goyal, Arun Kumar Gupta, Praveen Mathur
BACKGROUND: The association of neonatal intestinal obstruction with situs inversus totalis is extremely rare with only few cases reported in the literature to date. This association poses dilemmas in management. We present two such cases (of Indian origin), and briefly discuss the pertinent literature and measures to prevent unfavorable outcome. CASE PRESENTATION: Case 1: a 1-month-old preterm (1300 g) male neonate belonging to Hindu (Indian) ethnicity presented with recurrent bile-stained vomiting, non-passage of stools and epigastric fullness...
September 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28915317/the-theoretical-reliability-of-pcr-based-fish-viral-diagnostic-methods-is-critically-affected-when-they-are-applied-to-fish-populations-with-low-prevalence-and-virus-loads
#4
C P Dopazo, P Moreno, J G Olveira, J J Borrego
AIMS: The reliability of PCR techniques is an important issue in viral diagnosis, and it is even crucial when they must be applied for detection of viruses in asymptomatic carriers. The problems will arise when the aim is to study fish wild populations, where the viral loads and prevalence values are extremely low. We have evaluated several PCR procedures employed by two laboratories for monitoring fish captured in several oceanographic campaigns performed in the Gulf of Cádiz. METHODS AND RESULTS: To evaluate the reliability of different diagnostics test used, we have re-analyzed fish samples that had been previously subjected to diagnosis for a surveillance of viruses performed in 2010-2011 in wild fish populations...
September 15, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28906287/racial-disparities-in-sepsis-related-in-hospital-mortality-using-a-broad-case-capture-method-and-multivariate-controls-for-clinical-and-hospital-variables-2004-2013
#5
Jenna M Jones, Kathryn R Fingar, Melissa A Miller, Rosanna Coffey, Marguerite Barrett, Thomas Flottemesch, Kevin C Heslin, Darryl T Gray, Ernest Moy
OBJECTIVES: As sepsis hospitalizations have increased, in-hospital sepsis deaths have declined. However, reported rates may remain higher among racial/ethnic minorities. Most previous studies have adjusted primarily for age and sex. The effect of other patient and hospital characteristics on disparities in sepsis mortality is not yet well-known. Furthermore, coding practices in claims data may influence findings. The objective of this study was to use a broad method of capturing sepsis cases to estimate 2004-2013 trends in risk-adjusted in-hospital sepsis mortality rates by race/ethnicity to inform efforts to reduce disparities in sepsis deaths...
September 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28895706/-neonatal-renal-abscess-a-diagnostic-and-therapeutic-challenge-a-clinical-case
#6
Sebastián Argañaraz Gonçalves, Enrique Casanueva, Silvia Filipis, Carla Gandini, M Vanesa Rodríguez, Adriana Santiago, Aída Vázquez, Roberto Vagni
Renal abscess is a rare disease in newborn, but severe consequences can occur: sepsis with high mortality, renal scar formation and risk of chronic renal failure. A neonate with unilateral renal abscess due to Staphylococcus aureus is reported, with septicemia, with no other suppurative focus, nor with urinary malformation, with good clinical evolution with intravenous antibiotics and without surgical treatment, but with renal scars sequel. From this case, the strategies of diagnosis, treatment and followup of the renal abscess in a neonate are analyzed, emphasizing the early diagnosis to avoid renal scars...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28892991/neisseria-meningitidis-causing-multiple-cerebral-abscesses-in-early-neonatal-period-case-report-and-review-of-literature
#7
Laxman Basani, Roja Aepala
Neisseria meningitidis is a rare cause of meningitis and septicemia in neonates. There are few published case reports of neonatal meningococcal meningitis complicated by subdural empyema, cerebral abscess and hydrocephalus. Few cases of neonatal meningococcal meningitis have been reported in the literature with none of them having the complication of multiple cerebral abscesses in early neonatal period (<seven days of life). We report a case of meningococcal meningitis with multiple cerebral abscesses which presented on fifth day of life and developed hydrocephalus at five weeks of life requiring a Ventriculo Peritoneal (VP) shunt...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28892312/-case-report-emphysematous-cystitis
#8
M Piraprez, M Ben Chehida, M Fillet
The emphysematous cystitis is a rare condition characterized by the presence of air in the wall and/or the bladder lumen. The clinical expression of this cystitis is variable. Some patients complain of abdominal pain or urinary symptoms. Other may present only pneumaturia or be totally asymptomatic. This condition is considered as potentially severe since it can lead to an emphysematous pyelonephritis with septicemia and septic shock. Peritonitis may also occur in case of necrosis and perforation of the bladder wall...
September 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28892106/biochemical-characterization-of-a-catalase-from-vibrio-vulnificus-a-pathogen-that-causes-gastroenteritis
#9
Jihua Pei, Haijun Wang, Limin Wu, Shenglong Xia, Changlong Xu, Bo Zheng, Tianya Li, Yi Jiang
Vibrio vulnificus is a virulent human pathogen causing gastroenteritis and possibly life threatening septicemia in patients. Most V. vulnificus are catalase positive and can deactivate peroxides, thus allowing them to survive within the host. In the study presented here, a catalase from V. vulnificus (CAT-Vv) was purified to homogeneity after expression in Escherichia coli. The kinetics and function of CAT-Vv were examined. CAT-Vv catalyzed the reduction of H2O2 at an optimal pH of 7.5 and temperature of 35°C...
2017: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/28891746/impact-of-sex-on-systemic-lupus-erythematosus-related-causes-of-premature-mortality-in-the-united-states
#10
Titilola Falasinnu, Yashaar Chaichian, Julia F Simard
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is a source of significantly decreased life expectancy in the United States. This study investigated causes of deaths among males and females with SLE. MATERIALS AND METHODS: This cross-sectional study used the national death certificate database of ∼2.7 million death records in the United States, 2014. SLE was defined using Tenth Revision of the International Classification of Diseases codes: M32...
September 11, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28888883/host-responses-and-bacterial-colonization-following-inoculation-of-pasteurella-multocida-p52-strain-into-unvaccinated-and-aluminum-hydroxide-gel-hemorrhagic-septicemia-vaccinated-mice
#11
Mamta Singh, Rishendra Verma, Ramane Sangram Pandit, Najeeb Ul Tarfain
Hemorrhagic septicemia is a highly infectious and contagious disease caused by Pasteurella multocida serogroup B:2 in tropical Asian and African countries. The acute inflammatory responses induced by Pasteurella multocida are the main cause of death in hemorrhagic septicemia. Therefore, present study was undertaken to examine the blood cytokine expression profiles (TNF-α, IL-1β, and IL-6), bacterial colonization and histopathological changes of intraperitoneally and subcutaneously challenged vaccinated and unvaccinated mice with 10(2) CFU of P...
September 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28887787/pneumococcal-vaccines-how-many-serotypes-are-enough
#12
REVIEW
Aaradhana Singh, A K Dutta
Streptococcus pneumoniae causes meningitis, pneumonia, septicemia, arthritis, sinusitis and otitis media specially in children and over 65 y age groups. It contributes significantly to under-five mortality and morbidity worldwide as well as in India. Use of pneumococcal vaccine seems to be the most effective measure to decrease the disease burden and reduction of under-five mortality. Many countries have already included Pneumococcal Conjugate Vaccines (PCV) in their National Immunization Programmes (NIP). Government of India has announced recently to include PCV13 in NIP in a phased manner...
September 9, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28883240/listeria-monocytogenes-septicemia-and-meningitis-caused-by-listeria-enteritis-complicating-ulcerative-colitis
#13
Takahiro Inoue, Toshinao Itani, Noriko Inomata, Kazuya Hara, Ikuhisa Takimoto, Shunya Iseki, Kensuke Hamada, Kanna Adachi, Shunsuke Okuyama, Yukari Shimada, Motohito Hayashi, Jun Mimura
An 80-year-old man, who had been diagnosed with ulcerative colitis, was admitted due to a fever and bloody diarrhea and was treated with a glucocorticoid and azathioprine. After 5 days, he developed an impaired consciousness, headache, and neck stiffness. A sample of the colonic mucosa, blood cultures, and cerebrospinal fluid revealed Listeria monocytogenes infection. Intravenous ampicillin improved the symptoms of fever, bloody diarrhea, and headache without any neurological sequelae. Physicians should consider that Listeria enteritis complicating ulcerative colitis can cause septicemia and meningitis in immunosuppressed patients...
September 6, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28879784/non-chemotherapy-drug-induced-neutropenia-an-update
#14
Emmanuel Andrès, Rachel Mourot-Cottet
To date, non-chemotherapy drug-induced severe neutropenia (neutrophil count of ≤0.5 x 10(9)/L) also called idiosyncratic drug-induced agranulocytosis is little discussed in the literature. In the present paper, we report and discuss the clinical data and management of this rare disorder. Areas covered: To do this, we carried out a review of the literature using PubMed database of the US National Library of Medicine. We also used data from the American Society of Hematology educational books, textbooks of Hematology and Internal medicine, and information gleaned from international meetings...
September 7, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28878382/pleomorphic-bacteria-like-structures-in-human-blood-represent-non-living-membrane-vesicles-and-protein-particles
#15
Jan Martel, Cheng-Yeu Wu, Pei-Rong Huang, Wei-Yun Cheng, John D Young
Although human blood is believed to be a sterile environment, recent studies suggest that pleomorphic bacteria exist in the blood of healthy humans. These studies have led to the development of "live-blood analysis," a technique used by alternative medicine practitioners to diagnose various human conditions, including allergies, cancer, cardiovascular disease and septicemia. We show here that bacteria-like vesicles and refringent particles form in healthy human blood observed under dark-field microscopy. These structures gradually increase in number during incubation and show morphologies reminiscent of cells undergoing division...
September 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28874381/efficacy-of-a-new-recrystallized-enrofloxacin-hydrochloride-dihydrate-against-leptospirosis-in-a-hamster-model
#16
Alma Carrascosa, Lilia Gutierrez, Alejandro De la Peña, Irma E Candanosa, Graciela Tapia, Hector Sumano
A trial on Syrian hamsters (Mesocricetus auratus) infected with Leptospira interrogans serovar Canicola was established to compare treatment efficacies of daily IM injections of either 10 mg/kg of Baytril® 5% or the same dose of enrofloxacin dihydrate-hydrochloride (enro-C). Hamsters were experimentally infected via oral submucosa with 400 microorganisms/animal, in a sequential time-schedule to align initial treatment day as follows: group BE24 treated with Baytril® daily for 7 days after 24 of infection; group enro-C24 treated with enro-C as in group BE24; group BE74 treated also with Baytril®, but starting 72 h after infection; group enro-C74 treated as group BE74 but injecting enro-C...
September 5, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28874042/adverse-drug-reaction-monitoring-during-antimicrobial-therapy-for-septicemia-patients-at-a-university-hospital-in-new-delhi
#17
Md Shamshir Alam, Krishna Kolappa Pillai, Syed Aliul Hasan Abdi, Prem Kapur, Paru Kutty Pillai, Kandasamy Nagarajan
Background/Aims: Adverse drug reaction (ADR) is an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product. The present study was conducted in order to monitor the frequency and severity of ADR during antimicrobial therapy of septicemia. Methods: A prospective, observational, and noncomparative study was conducted over a period of 6 months on patients of septicemia admitted at a university hospital. Naranjo algorithm scale was used for causality assessment...
September 6, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28866274/biological-parameters-immune-enzymes-and-histological-alterations-in-the-livers-of-grass-carp-infected-with-aeromonas-hydrophila
#18
Shen-Tong Wang, Xin-Zhan Meng, Li-Sen Li, Yun-Fei Dang, Yuan Fang, Yubang Shen, Xiao-Yan Xu, Rong-Quan Wang, Jia-Le Li
Aeromonas hydrophila is the causative agent of bacterial septicemia that is frequently observed in grass carp, Ctenopharyngodon idellus. In this study, we evaluated the biological parameters and immune enzymes in the liver of grass carp following A. hydrophila infection and quantified the alterations in liver histology using a semi-quantitative system. For the biological parameters, we found that the liver somatic index (LSI) was more sensitive than Fulton's condition factor (CF) and was significantly decreased at three days post-injection (DPI)...
August 31, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28861049/characterization-of-histopathological-and-ultrastructural-changes-in-channel-catfish-experimentally-infected-with-virulent-aeromonas-hydrophila
#19
Hossam Abdelhamed, Iman Ibrahim, Wes Baumgartner, Mark L Lawrence, Attila Karsi
A highly virulent clonal population of Aeromonas hydrophila (vAh) has been the cause of recent motile Aeromonas septicemia epizootic in channel catfish (Ictalurus punctatus) farms in the Southeastern United States. The pathology of the disease caused by vAh has not been studied well yet. Thus, our aim was to determine histopathological and ultrastructural changes in channel catfish following vAh challenge. To accomplish this, catfish fingerlings were challenged with vAh (strain ML09-119) by bath. Six fish per each time point were collected at 1, 3, 5, 6, 24, and 48 h for light microscopy, and six fish were collected at 48 h for transmission electron microscopy (TEM)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28859189/trends-in-adult-cancer-related-emergency-department-utilization-an-analysis-of-data-from-the-nationwide-emergency-department-sample
#20
Donna R Rivera, Lisa Gallicchio, Jeremy Brown, Benmei Liu, Demetrios N Kyriacou, Nonniekaye Shelburne
Importance: The emergency department (ED) is used to manage cancer-related complications among the 15.5 million people living with cancer in the United States. However, ED utilization patterns by the population of US adults with cancer have not been previously evaluated or described in published literature. Objective: To estimate the proportion of US ED visits made by adults with a cancer diagnosis, understand the clinical presentation of adult patients with cancer in the ED, and examine factors related to inpatient admission within this population...
August 31, 2017: JAMA Oncology
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