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https://www.readbyqxmd.com/read/29208867/surgical-treatment-of-hepatolithiasis-our-experience-in-bangabandhu-sheikh-mujib-medical-university
#1
B C Das, M M Rahman, A K Biswas, S Shahriar, A Ahmed, Z R Khan
Recurrent cholangitis and sepsis are common complications after surgical treatment for hepatolithiasis as total clearance is not always possible. This retrospective study is designed to see the effect of our treatment for hepatolithiasis on stone clearance and post operative complications. We have treated 60 patients with hepatolithiasis surgically from September 2010 to September 2016 in the Department of Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Various operative procedures were applied on the basis of location of stone and status of biliary tree...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29205230/can-protein-restriction-set-up-t-lymphocytes-favorably-for-their-activation-against-pathogens-through-myc
#2
Jung-Eun Lee
One area that presents a significant threat to global health is infectious diseases. With increasing prevalence of antibiotic-resistant bacteria [1], opportunistic infections are a growing concern for human societies. In 2009, there were 89,000 deaths caused by pneumonia, septicemia, and influenza virus in the United States alone [2]. Antibiotic-resistant bacteria increase the risk of secondary infection that is associated with many standard medical procedures such as organ transplantation, chemotherapy, dialysis, and elective surgery [1]...
2017: MOJ Lymphology Phlebol
https://www.readbyqxmd.com/read/29204301/human-infection-with-fusobacterium-necrophorum-without-jugular-venous-thrombosis-a-varied-presentation-of-lemierre-s-syndrome
#3
Muhammad Asim Rana, Yashwant Kumar, Abdullah Ali Lashari, Ahmed F Mady
Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by Fusobacterium necrophorum also known as Necrobacillus and also by other microorganisms like Staphylococcus, Streptococcus, Peptostreptococcus, and Bacteroides. Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. It is also known as forgotten disease because of its rarity...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29203546/use-of-proteins-identified-through-a-functional-genomic-screen-to-develop-a-protein-subunit-vaccine-that-provides-significant-protection-against-virulent-streptococcus-suis-in-pigs
#4
Susan L Brockmeier, Crystal L Loving, Tracy L Nicholson, Jinhong Wang, Sarah E Peters, Lucy Weinert, Roy Chaudhuri, David J Seilly, Paul R Langford, Andrew Rycroft, Brendan W Wren, Duncan J Maskell, Alexander W Tucker
Streptococcus suis is a bacterium commonly carried in the respiratory tract that is also one of the most important invasive pathogens of swine, commonly causing meningitis, arthritis, and septicemia. Due to the existence of many serotypes and a wide range of immune evasion capabilities efficacious vaccines are not readily available. The selection of S. suis protein candidates for inclusion in a vaccine was accomplished by identifying fitness genes through a functional genomics screen and selecting conserved predicted surface-associated proteins...
December 4, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29201149/complete-genome-sequence-of-the-vibrio-vulnificus-strain-vv2014djh-a-human-pathogenic-bacterium-isolated-from-a-death-case-in-china
#5
Junhang Pan, Yi Sun, Wenwu Yao, Haiyan Mao, Yanjun Zhang, Muyuan Zhu
Background: Vibrio vulnificus, an opportunistic pathogen, is the causative agent of life-threatening septicemia and severe wound infections. However, the pathogenicity and virulence factors of V. vulnificus are not fully understood. Here we report the complete genome sequence of V. vulnificus VV2014DJH, which was isolated from a death case. Results: The genome of the V. vulnificus VV2014DJH contains two circular chromosomes with a mean G+C content of 46.8%, but does not consists of any plasmids...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/29196924/cutaneotrichosporon-trichosporon-debeurmannianum-a-rare-yeast-isolated-from-blood-and-urine-samples
#6
Reema Nath, Pallabi Sargiary, Biswajyoti Borkakoty, Pratap Parida
Cutaneotrichosporon (Trichosporon) debeurmannianum is a rarely isolated yeast from clinical samples. Nine isolates of this yeast were identified from clinical samples within a period of 3 years from June 2012 to May 2015. These isolates were from blood and urine samples sent to a clinical mycology laboratory of a tertiary care hospital in Assam, North East India. Clinically, the patients were diagnosed as septicemia and urinary tract infection. The age of the patients ranged from 2 to 50 years. Identification was made by sequencing the ITS region of ribosomal RNA gene...
December 1, 2017: Mycopathologia
https://www.readbyqxmd.com/read/29193418/causes-and-predictors-of-30-day-readmission-after-cardiovascular-implantable-electronic-devices-implantation-insights-from-nationwide-readmissions-database
#7
Shahzad Ahmad, Muhammad Bilal Munir, Michael S Sharbaugh, Andrew D Althouse, Deepak Kumar Pasupula, Samir Saba
INTRODUCTION: Readmissions are a burden on health care resources and have negative impact on patients. Cardiovascular Implantable Electronic Devices (CIED) are frequently used in the management of rhythm disorders and advanced heart failure. We assessed 30-day readmissions in patients admitted for CIED implantation in a sample of United States patients. METHODS: Data were extracted from Nationwide Readmissions Database for calendar year 2013. Patients admitted for CIED implantation were identified using ICD-9 codes...
November 28, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29191910/host-dnases-prevent-vascular-occlusion-by-neutrophil-extracellular-traps
#8
Miguel Jiménez-Alcázar, Chandini Rangaswamy, Rachita Panda, Josephine Bitterling, Yashin J Simsek, Andy T Long, Rostyslav Bilyy, Veit Krenn, Christoph Renné, Thomas Renné, Stefan Kluge, Ulf Panzer, Ryushin Mizuta, Hans Georg Mannherz, Daisuke Kitamura, Martin Herrmann, Markus Napirei, Tobias A Fuchs
Platelet and fibrin clots occlude blood vessels in hemostasis and thrombosis. Here we report a noncanonical mechanism for vascular occlusion based on neutrophil extracellular traps (NETs), DNA fibers released by neutrophils during inflammation. We investigated which host factors control NETs in vivo and found that two deoxyribonucleases (DNases), DNase1 and DNase1-like 3, degraded NETs in circulation during sterile neutrophilia and septicemia. In the absence of both DNases, intravascular NETs formed clots that obstructed blood vessels and caused organ damage...
December 1, 2017: Science
https://www.readbyqxmd.com/read/29188475/current-perspectives-on-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis
#9
REVIEW
Marianne Lerch, Carlo Mainetti, Benedetta Terziroli Beretta-Piccoli, Thomas Harr
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies and an early recognition and appropriate management is decisive for the survival. SJS/TEN manifest with an "influenza-like" prodromal phase (malaise, fever), followed by painful cutaneous and mucous membrane (ocular, oral, and genital) lesions, and other systemic symptoms. The difference between SJS, SJS/TEN overlap, and TEN is defined by the degree of skin detachment: SJS is defined as skin involvement of < 10%, TEN is defined as skin involvement of > 30%, and SJS/TEN overlap as 10-30% skin involvement...
November 29, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29179884/mortality-pattern-in-otorhinolaryngology-ward-a-5-years%C3%A2-retrospective-study-at-an-urban-tertiary-health-care-center-in-india
#10
Vivek Kumar, Satish Kumar, Naresh Chandra Sharma, Badal Kumar
BACKGROUND: To recognize deaths in the otorhinolaryngology indoor wards, determine the reason behind the mortalities and recommend modifications for betterment of patient care and surgical outcomes. METHOD: Data was collected from the mortality register, operation theatre registers, ward registers and case notes of patients declared dead at an urban tertiary health care center in India for a period of 5 years; from January 2012 to December 2016. The data included date of admission, age, sex, educational status, residence, and clinical diagnosis, course of hospital stay and medical cause of death...
October 2017: Biomedical Journal
https://www.readbyqxmd.com/read/29173582/staphylococcus-agnetis-a-potential-pathogen-in-broiler-breeders
#11
Louise Ladefoged Poulsen, Ida Thøfner, Magne Bisgaard, Rikke Heidemann Olsen, Jens Peter Christensen, Henrik Christensen
In this study, four broiler parent flocks have been followed from the onset of the production period (week 20) until slaughter (week 60). Every week, approximately ten dead broiler breeders, randomly selected among birds dead on their own, were collected and subjected to a full post mortem analysis including bacteriological examination. In total 997 breeders were investigated and for the first time Staphylococcus agnetis was isolated in pure culture from cases of endocarditis and septicemia from 16 broiler breeders...
December 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29164068/comparative-pan-genome-analysis-of-piscirickettsia-salmonis-reveals-genomic-divergences-within-genogroups
#12
Guillermo Nourdin-Galindo, Patricio Sánchez, Cristian F Molina, Daniela A Espinoza-Rojas, Cristian Oliver, Pamela Ruiz, Luis Vargas-Chacoff, Juan G Cárcamo, Jaime E Figueroa, Marcos Mancilla, Vinicius Maracaja-Coutinho, Alejandro J Yañez
Piscirickettsia salmonis is the etiological agent of salmonid rickettsial septicemia, a disease that seriously affects the salmonid industry. Despite efforts to genomically characterize P. salmonis, functional information on the life cycle, pathogenesis mechanisms, diagnosis, treatment, and control of this fish pathogen remain lacking. To address this knowledge gap, the present study conducted an in silico pan-genome analysis of 19 P. salmonis strains from distinct geographic locations and genogroups. Results revealed an expected open pan-genome of 3,463 genes and a core-genome of 1,732 genes...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29163999/childhood-lupus-nephritis-12-years-of-experience-from-a-developing-country-s-perspective
#13
Moumita Samanta, Madhumita Nandi, Rakesh Mondal, Avijit Hazra, Sumatra Sarkar, Tapas Sabui, Chanchal Kumar Kundu, Arnab Biswas
Objective: To assess the long-term outcome of lupus nephritis in children with systemic lupus erythematosus followed up over 12 years at a tertiary care teaching hospital in Eastern India. Material and Methods: This is a retrospective observational study of the clinicopathological presentation, management, and outcome in 46 children with lupus nephritis over a period of 12 years at a tertiary teaching hospital in Eastern India. Mortality was compared between different lupus classes and therapy groups with Kaplan-Meier analysis and log-rank test...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29163526/nucleated-teleost-erythrocytes-play-an-nk-lysin-and-autophagy-dependent-role-in-antiviral-immunity
#14
Patricia Pereiro, Alejandro Romero, Patricia Díaz-Rosales, Amparo Estepa, Antonio Figueras, Beatriz Novoa
With the exception of mammals, vertebrate erythrocytes are nucleated. Nevertheless, these cells are usually considered as mere carriers of hemoglobin. In this work, however, we describe for the first time an unrecognized role of teleost red blood cells (RBCs). We found that Nk-lysin (Nkl), an antimicrobial peptide produced by NK-cells and cytotoxic T-lymphocytes, was also expressed in flatfish turbot (Scophthalmus maximus) erythrocytes. Although the antiviral role of Nkl remains to be elucidated, we found a positive correlation between the transcription of nkl and the resistance to an infection with Rhabdovirus in a teleost fish...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29163452/the-opportunistic-pathogen-vibrio-vulnificus-produces-outer-membrane-vesicles-in-a-spatially-distinct-manner-related-to-capsular-polysaccharide
#15
Cheri M Hampton, Ricardo C Guerrero-Ferreira, Rachel E Storms, Jeannette V Taylor, Hong Yi, Paul A Gulig, Elizabeth R Wright
Vibrio vulnificus, a bacterial species that inhabits brackish waters, is an opportunistic pathogen of humans. V. vulnificus infections can cause acute gastroenteritis, invasive septicemia, tissue necrosis, and potentially death. Virulence factors associated with V. vulnificus include the capsular polysaccharide (CPS), lipopolysaccharide, flagellum, pili, and outer membrane vesicles (OMVs). The aims of this study were to characterize the morphology of V. vulnificus cells and the formation and arrangement of OMVs using cryo-electron microscopy (cryo-EM)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29160493/neonatal-appendicitis-a-survival-case-study
#16
Izabela Linha Secco, Taine Costa, Etiene Letícia Leone de Moraes, Márcia Helena de Souza Freire, Mitzy Tannia Reichembach Danski, Regina Paula Guimarães Vieira Cavalcante
OBJECTIVE: To report a case of neonatal appendicitis in a children's hospital in southern Brazil, demonstrating the impact on neonatal survival. METHOD: Case study with data collection from medical records, approved by the Institution and Ethics Committee for Research with Human Beings. RESULTS: The clinical picture is initially characterized by food intolerance, evolving to hypoactivity, alteration of vital signs and septicemia due to intestinal perforation...
November 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29160221/evaluation-of-blue-mussel-mytilus-edulis-as-vector-for-viral-hemorrhagic-septicemia-virus-vhsv
#17
Kwang Il Kim, Young Chul Kim, Woo Ju Kwon, Hyun Do Jeong
When viral diseases occur in aquaculture farms, the virus released into the seawater from infected animals can re-infect other susceptible species or accumulate in filter-feeding organisms. We conducted a viral hemorrhagic septicemia virus (VHSV) survivability analysis of blue mussel Mytilus edulis digestive enzymes, viral depuration, and infectivity tests via in vitro and in vivo inoculation to evaluate the infectious state. VHSV particles were not completely digested within 24 h in vitro and were maintained for 7 d in the mussel digestive gland...
November 21, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29160219/complete-sequences-of-4-viral-hemorrhagic-septicemia-virus-ivb-isolates-and-their-virulence-in-northern-pike-fry
#18
Rodman G Getchell, Emily R Cornwell, Steven Bogdanowicz, Jose Andrés, William N Batts, Gael Kurath, Rachel Breyta, Joanna G Choi, John M Farrell, Paul R Bowser
Four viral hemorrhagic septicemia virus (VHSV) genotype IVb isolates were sequenced, their genetic variation explored, and comparative virulence assayed with experimental infections of northern pike Esox lucius fry. In addition to the type strain MI03, the complete 11183 bp genome of the first round goby Neogobius melanostomus isolate from the St. Lawrence River, and the 2013 and 2014 isolates from gizzard shad Dorosoma cepedianum die-offs in Irondequoit Bay, Lake Ontario and Dunkirk Harbor, Lake Erie were all deep sequenced on an Illumina platform...
November 21, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29151992/aerococcus-urinae-and-aerococcus-sanguinicola-susceptibility-testing-of-120-isolates-to-six-antimicrobial-agents-using-disk-diffusion-eucast-etest-and-broth-microdilution-techniques
#19
Derya Carkaci, Xiaohui C Nielsen, Kurt Fuursted, Robert Skov, Ole Skovgaard, Emilio P Trallero, Reto Lienhard, Jenny Åhman, Erika Matuschek, Gunnar Kahlmeter, Jens J Christensen
Background: Aerococcus urinae and Aerococcus sanguinicola are relatively newcomers and emerging organisms in clinical and microbiological practice. Both species have worldwide been associated with urinary tract infections. More rarely cases of bacteremia/septicemia and infective endocarditis have been reported. Treatment options are therefore important. Just recently, European recommendations on susceptibility testing and interpretive criteria have been released. Objective: In this investigation 120 A...
2017: Open Microbiology Journal
https://www.readbyqxmd.com/read/29142521/fatal-infections-in-older-patients-with-inflammatory-bowel-disease-on-anti-tumor-necrosis-factor-therapy
#20
Way-Seah Lee, Najib Azmi, Ruey-Terng Ng, Sik-Yong Ong, Sasheela Sri La Ponnampalavanar, Sanjiv Mahadeva, Ida Hilmi
Anti-tumor necrosis factor (anti-TNF) is highly effective in inflammatory bowel disease (IBD); however, it is associated with an increased risk of infections, particularly in older adults. We reviewed 349 patients with IBD, who were observed over a 12-month period, 74 of whom had received anti-TNF therapy (71 patients were aged <60 years and 3 were aged ≥60 years). All the 3 older patients developed serious infectious complications after receiving anti-TNFs, although all of them were also on concomitant immunosuppressive therapy...
October 2017: Intestinal Research
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