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https://www.readbyqxmd.com/read/29667799/shrink-that-frown-botulinum-toxin-therapy-is-lifting-the-face-of-psychiatry
#1
M Axel Wollmer, Insa Neumann, Michelle Magid, Tillmann H Kruger
Treating glabellar frown lines with injections of botulinum toxin is the most frequently applied procedure in aesthetic medicine. In addition to its cosmetic effect, botulinum toxin may also positively modulate mood and affect, which may contribute to its popularity. A series of clinical studies has shown that this modulation can be used in the treatment of major depression. After a single glabellar treatment with botulinum toxin, patients suffering from unipolar depression experienced a quick, strong and sustained improvement in the symptoms of depression...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29667712/trajectories-of-alcohol-consumption-in-u-s-military-veterans-results-from-the-national-health-and-resilience-in-veterans-study
#2
Brian S Fuehrlein, Lorig K Kachadourian, Elizabeth K DeVylder, Louis A Trevisan, Marc N Potenza, John H Krystal, Steven M Southwick, Robert H Pietrzak
BACKGROUND AND OBJECTIVES: While alcohol use disorder is prevalent in U.S. veterans, little is known about the nature and determinants of predominant trajectories of alcohol consumption in this population. The objective of the current study was to identify predominant trajectories of alcohol consumption over a 4-year period, and baseline determinants of these trajectories in veterans. METHODS: Data were analyzed from the National Health and Resilience in Veteran Study, which surveyed a nationally representative sample of 3,157 veterans (Wave 1)...
April 18, 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29667694/a-grounded-theory-investigation-into-sophomore-students-recall-of-depression-during-their-freshman-year-in-college-a-pilot-study
#3
Julie M Brandy, Theresa A Kessler, Christina H Grabarek
Using a grounded theory approach, the current descriptive qualitative design was conducted with sophomore students to understand the meaning participants gave their freshman experiences with depression. Twelve participants were recruited using scripted class announcements across campus. After informed consent, interviews began with the question: What was the experience of your freshman year in college? All interviews were completed with the primary investigator and transcribed verbatim. Interviews were analyzed using constant comparative methodology...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29667152/falls-in-mexican-older-adults-aged-60-years-and-older
#4
Luis M Valderrama-Hinds, Soham Al Snih, Nai-Wei Chen, Martin A Rodriguez, Rebeca Wong
BACKGROUND: Falls are a major cause of disability, morbidity, institutionalization, and mortality in older adults. OBJECTIVES: The purpose of the study was to examine the risk factors for falls among Mexican older adults aged 60 years and older. METHODS: This study included 6247 participants and their spouse or partner aged 60 years and older from the Mexican Health and Aging Study, an ongoing longitudinal study (2001-2012) conducted in Mexico...
April 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29666778/psychiatric-morbidity-perceived-stress-and-ways-of-coping-among-parents-of-children-with-intellectual-disability-in-lahore-pakistan
#5
Muhammad H Sheikh, Sania Ashraf, Nazish Imran, Sadia Hussain, Muhammad W Azeem
Background This study assessed anxiety and depression levels among parents of children with intellectual disability (ID) and analyzed their coping strategies. Methods One hundred parents of children with ID were recruited through child psychiatry outpatient services in a tertiary care setting in Lahore, Pakistan. A structured questionnaire including sociodemographic details, the Agha Khan University Anxiety Depression Scale, the Family Stress and Coping Questionnaire, Brief COPE questionnaire, and Support questionnaire were used for data collection...
February 16, 2018: Curēus
https://www.readbyqxmd.com/read/29666751/an-open-trial-of-individualized-face-to-face-cognitive-behavior-therapy-for-psychological-distress-in-parents-of-children-after-end-of-treatment-for-childhood-cancer-including-a-cognitive-behavioral-conceptualization
#6
Lisa Ljungman, Martin Cernvall, Ata Ghaderi, Gustaf Ljungman, Louise von Essen, Brjánn Ljótsson
Objective: A subgroup of parents of children who have been treated for childhood cancer report high levels of psychological distress. To date there is no empirically supported psychological treatment targeting cancer-related psychological distress in this population. The aim of the current study was to test the feasibility and preliminarily evaluate the effect of individualized face-to-face cognitive behavior therapy (CBT) for parents of children after the end of treatment for childhood cancer...
2018: PeerJ
https://www.readbyqxmd.com/read/29666637/recovery-of-chronic-stress-triggered-changes-of-hippocampal-glutamatergic-transmission
#7
Min Lin, Gonglin Hou, Ying Zhao, Ti-Fei Yuan
Chronic stress results in neurochemical, physiological, immune, molecular, cellular, and structural changes in the brain and often dampens the cognition. The hippocampus has been one major focus in studying the stress responsivity and neural mechanisms underlying depression. Both acute and chronic stress stimuli lead to dynamic changes in excitatory transmission in the hippocampus. The present study examined the potential effects of spontaneous recovery after chronic stress on spatial memory function and glutamatergic transmission in the hippocampus...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29665820/work-impairment-osteoarthritis-and-health-related-quality-of-life-among-employees-in-japan
#8
Ken Nakata, Toshinaga Tsuji, Jeffrey Vietri, Dena H Jaffe
BACKGROUND: Osteoarthritis (OA) is one of the most common causes of health and work impairment; however, this relationship, especially in Japan, is not well characterized. This study examined work impairment and OA in Japanese workers, specifically the relationship with health-related quality of life (HRQoL) and health status. METHODS: This retrospective, cross-sectional observational study included the data of employed adults with a self-reported OA diagnosis from the 2014 Japan National Health and Wellness Survey...
April 17, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29665516/-cool-and-hot-executive-functions-in-suicide-attempters-with-major-depressive-disorder
#9
Ming-Chou Ho, Yi-Chieh Hsu, Mong-Liang Lu, Michael Gossop, Vincent Chin-Hung Chen
RATIONALE: The World Health Organization reports that, by 2030, depression is expected to be the largest contributor to disease burden. Only small proportion of patients with major depressive disorder (MDD) achieves remission and the majority of them do not achieve long-term functional recovery. One of the neuropsychological domains that have been shown to be particularly impaired in depression, is that of executive function (EF). OBJECTIVES: We examined whether the patients with MDD with and without suicide attempts had deteriorated 'cool' EF and 'hot' EF...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29665490/smaller-hippocampal-volume-in-current-but-not-in-past-depression-in-comparison-to-healthy-controls-minor-evidence-from-an-older-adults-sample
#10
Ismaïl Bensassi, Jorge Lopez-Castroman, Jerome J Maller, Chantal Meslin, Marilyn Wyart, Karen Ritchie, Philippe Courtet, Sylvaine Artero, Raffaella Calati
BACKGROUND: Structural neuroimaging studies revealed a consistent pattern of volumetric reductions in both hippocampus (HC) and anterior cingulate cortex (ACC) of individuals with major depressive episode(s) (MDE). This study investigated HC and ACC volume differences in currently depressed individuals (n = 150), individuals with a past lifetime MDE history (n = 79) and healthy controls (n = 287). METHODS: Non-demented individuals were recruited from a cohort of community-dwelling older adults (ESPRIT study)...
April 9, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29665163/lowered-quality-of-life-in-mood-disorders-is-associated-with-increased-neuro-oxidative-stress-and-basal-thyroid-stimulating-hormone-levels-and-use-of-anticonvulsant-mood-stabilizers
#11
Caroline Sampaio Nunes, Michael Maes, Chutima Roomruangwong, Juliana Brum Moraes, Kamila Landucci Bonifacio, Heber Odebrecht Vargas, Decio Sabbatini Barbosa, George Anderson, Luiz Gustavo Piccoli de Melo, Stoyanov Drozdstoj, Estefania Moreira, André F Carvalho, Sandra Odebrecht Vargas Nunes
RATIONALE, AIMS: Major affective disorders including bipolar disorder (BD) and major depressive disorder (MDD) are associated with impaired health-related quality of life (HRQoL). Oxidative stress and subtle thyroid abnormalities may play a pathophysiological role in both disorders. Thus, the current study was performed to examine whether neuro-oxidative biomarkers and thyroid-stimulating hormone (TSH) levels could predict HRQoL in BD and MDD. METHODS: This cross-sectional study enrolled 68 BD and 37 MDD patients and 66 healthy controls...
April 17, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29664579/chronic-intra-oral-pain-and-depressive-symptoms-in-japanese-community-dwelling-elderly-a-longitudinal-study
#12
L Hanindriyo, A Yoshihara, T Takiguchi, H Miyazaki
OBJECTIVE: The incidence of major depressive disorder in the elderly ranges from 0.2 to 14.1/100 person-years, and the incidence of clinically relevant depressive symptoms is 6.8/100 person-years. This study aimed to assess the longitudinal relationship between chronic intra oral pain and depressive symptom in Japanese elderly. BASIC RESEARCH DESIGN: 3-year cohort study. PARTICIPANTS: 212 community-dwelling seniors (129 men, 83 women) aged 77 years residing in the city of Niigata, Japan in 2005...
April 17, 2018: Community Dental Health
https://www.readbyqxmd.com/read/29664187/exercise-interventions-and-patient-beliefs-for-people-with-hip-knee-or-hip-and-knee-osteoarthritis-a-mixed-methods-review
#13
REVIEW
Michael Hurley, Kelly Dickson, Rachel Hallett, Robert Grant, Hanan Hauari, Nicola Walsh, Claire Stansfield, Sandy Oliver
BACKGROUND: Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population is unknown. OBJECTIVES: To improve our understanding of the complex inter-relationship between pain, psychosocial effects, physical function and exercise...
April 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29664050/association-between-perceived-stressfulness-of-stressful-life-events-and-the-suicidal-risk-in-chinese-patients-with-major-depressive-disorder
#14
Jing-Yu Lin, Yu Huang, Yun-Ai Su, Xin Yu, Xiao-Zhen Lyu, Qi Liu, Tian-Mei Si
Background: Patients with major depressive disorder (MDD) usually have high risk of suicidality. Few studies have investigated the effects of stressful life events (SLEs) on the risk of suicide in Chinese patients who have developed MDD. This study aimed to investigate the impact of SLEs on suicidal risk in Chinese patients with MDD. Methods: In total, 1029 patients with MDD were included from nine psychiatric hospitals to evaluate the impact of SLEs on suicidal risk...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29662259/psychometric-validation-of-the-columbia-suicide-severity-rating-scale-in-spanish-speaking-adolescents
#15
Daniel Serrani Azcurra
Introduction: Adolescent suicide is a major public health issue, and early and accurate detection is of great concern. There are many reliable instruments for this purpose, such as the Columbia-Suicide severity rating scale (C-SSRS), but no validation exists for Spanish speaking Latin American adolescents. Objetive: To assess psychometric properties and cut-off scores of the C-SSRS in Spanish speaking adolescents. Methods: Exploratory assessment with principal component analysis (PCA) and Varimax rotation, and confirmatory analysis (CFA) were performed on two groups with 782 and 834 participants respectively (N=1616)...
December 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29662202/stimulation-of-entorhinal-cortex-dentate-gyrus-circuitry-is-antidepressive
#16
Sanghee Yun, Ryan P Reynolds, Iraklis Petrof, Alicia White, Phillip D Rivera, Amir Segev, Adam D Gibson, Maiko Suarez, Matthew J DeSalle, Naoki Ito, Shibani Mukherjee, Devon R Richardson, Catherine E Kang, Rebecca C Ahrens-Nicklas, Ivan Soler, Dane M Chetkovich, Saïd Kourrich, Douglas A Coulter, Amelia J Eisch
Major depressive disorder (MDD) is considered a 'circuitopathy', and brain stimulation therapies hold promise for ameliorating MDD symptoms, including hippocampal dysfunction. It is unknown whether stimulation of upstream hippocampal circuitry, such as the entorhinal cortex (Ent), is antidepressive, although Ent stimulation improves learning and memory in mice and humans. Here we show that molecular targeting (Ent-specific knockdown of a psychosocial stress-induced protein) and chemogenetic stimulation of Ent neurons induce antidepressive-like effects in mice...
April 16, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29662059/genome-wide-association-study-of-depression-phenotypes-in-uk-biobank-identifies-variants-in-excitatory-synaptic-pathways
#17
David M Howard, Mark J Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E Marioni, Gail Davies, Jonathan R I Coleman, Clara Alloza, Xueyi Shen, Miruna C Barbu, Eleanor M Wigmore, Jude Gibson, Saskia P Hagenaars, Cathryn M Lewis, Joey Ward, Daniel J Smith, Patrick F Sullivan, Chris S Haley, Gerome Breen, Ian J Deary, Andrew M McIntosh
Depression is a polygenic trait that causes extensive periods of disability. Previous genetic studies have identified common risk variants which have progressively increased in number with increasing sample sizes of the respective studies. Here, we conduct a genome-wide association study in 322,580 UK Biobank participants for three depression-related phenotypes: broad depression, probable major depressive disorder (MDD), and International Classification of Diseases (ICD, version 9 or 10)-coded MDD. We identify 17 independent loci that are significantly associated (P < 5 × 10-8 ) across the three phenotypes...
April 16, 2018: Nature Communications
https://www.readbyqxmd.com/read/29661498/the-intra-day-dynamics-of-affect-self-esteem-tiredness-and-suicidality-in-major-depression
#18
Eimear Crowe, Michael Daly, Liam Delaney, Susan Carroll, Kevin M Malone
Despite growing interest in the temporal dynamics of Major Depressive Disorder (MDD), we know little about the intra-day fluctuations of key symptom constructs. In a study of momentary experience, the Experience Sampling Method captured the within-day dynamics of negative affect, positive affect, self-esteem, passive suicidality, and tiredness across clinical MDD (N= 31) and healthy control groups (N= 33). Ten symptom measures were taken per day over 6 days (N= 2231 observations). Daily dynamics were modeled via intra-day time-trends, variability, and instability in symptoms...
February 21, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29660859/permafrost-thaw-and-climate-warming-may-decrease-the-co-2-carbon-and-metal-concentration-in-peat-soil-waters-of-the-western-siberia-lowland
#19
T V Raudina, S V Loiko, A Lim, R M Manasypov, L S Shirokova, G I Istigechev, D M Kuzmina, S P Kulizhsky, S N Vorobyev, O S Pokrovsky
Soil pore waters are a vital component of the ecosystem as they are efficient tracers of mineral weathering, plant litter leaching, and nutrient uptake by vegetation. In the permafrost environment, maximal hydraulic connectivity and element transport from soils to rivers and lakes occurs via supra-permafrost flow (i.e. water, gases, suspended matter, and solutes migration over the permafrost table). To assess possible consequences of permafrost thaw and climate warming on carbon and Green House gases (GHG) dynamics we used a "substituting space for time" approach in the largest frozen peatland of the world...
April 11, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29660674/the-relation-of-borderline-personality-disorder-to-aggression-victimization-and-institutional-misconduct-among-prisoners
#20
Kelly E Moore, Robyn L Gobin, Heather L McCauley, Chien-Wen Kao, Stephanie M Anthony, Sheryl Kubiak, Caron Zlotnick, Jennifer E Johnson
OBJECTIVE: Borderline personality disorder (BPD) is highly prevalent among incarcerated populations; however, research has yet to examine whether prisoners diagnosed with BPD experience greater interpersonal dysfunction and institutional misconduct while incarcerated. PROCEDURE: This study drew from a sample of 184 male and female prisoners diagnosed with major depressive disorder (MDD) in a randomized trial of depression treatment. The presence of a BPD diagnosis (n = 69) was analyzed as a predictor of disciplinary incidents/infractions (i...
March 21, 2018: Comprehensive Psychiatry
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