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Marije Risselada, Matthew D Winter, Daniel D Lewis, Emily Griffith, Antonio Pozzi
BACKGROUND: Bone healing and assessment of the state of bone bridging is an important part of clinical orthopedics, whether for fracture healing or for follow up of osteotomy procedures. Tibial tuberosity advancement (TTA) is designed to restore stability in cruciate deficient stifle joints by advancing the tuberosity while creating an osteotomy gap. The current study aims to: 1) compare three different imaging modalities to assess bone healing: ultrasound, radiographs and computed tomography (CT) and, to 2) compare the effect of a gelatinous matrix (GM) versus a demineralized bone matrix mix (DBM mix) on bone healing and bridging of this osteotomy gap in 10 otherwise healthy client-owned dogs with cranial cruciate ligament insufficiency...
May 22, 2018: BMC Veterinary Research
K U Minchitha, H N Hareesh, K Venkatesh, M Shanty, N Nagaraju, N Kathyayini
Sulphate ion modified multiwalled carbon nanotubes (S-CNTs), mesoporous carbon (S-MC), zirconia (S-ZrO2), alumina (S-Al2O3) and silica (S-SiO2) were prepared by wet impregnation technique. The physico-chemical properties of the prepared materials were investigated by Powder-XRD, BET-Surface area and SEM-EDS analysis. Surface acidity of the materials was analyzed using TPD-NH3 and n-butyl amine titration methods. Catalytic activity of these materials was investigated in liquid phase transesterification of diethyl malonate with benzyl alcohol...
January 1, 2018: Journal of Nanoscience and Nanotechnology
Hossein Emami, Mohammadreza Hajihashemi, Sayed Ehsan Alavi, Abu Sahmah Mohd Supaat
A microwave photonics instantaneous frequency measurement receiver was conceived and practically demonstrated. The system is based on phase modulation inside a Sagnac loop and therefore needs no bias voltage, resulting in no DC bias drifts. The system provides a DC output whose amplitude is a function of input signal frequency, and thus no high-frequency photo-detector is required. Furthermore, the system exhibits a very good sensitivity without the aid of any sort of electrical noise cancellation techniques, such as lock-in amplification...
May 15, 2018: Optics Letters
Ke Huang, Mani Hossein-Zadeh
Injection locking is an effective technique for synchronization of oscillator networks and controlling the phase and frequency of individual oscillators. As such, exploring new mechanisms for injection locking of emerging oscillators is important for their usage in various systems. Here, we present the first demonstration of injection locking of a radiation pressure driven optomechanical oscillator (OMO) via acoustic waves. As opposed to previously reported techniques (based on pump modulation or direct application of a modulated electrostatic force), injection locking of OMO via acoustic waves does not require optical power modulation or physical contact with the OMO and it can be easily implemented on various platforms to lock different types of OMOs independent of their size and structure...
April 2, 2018: Optics Express
Joo Hyoun Kim, Chae Young Kim, Bobin Kang, Jungil Hong, Hyeon-Son Choi
The aim of this study was to investigate the effects of dibenzoylmethane (1,3-diphenyl-1,3-propanedione, DBM) from licorice roots on lipid accumulation and reactive oxygen species (ROS) production in 3T3-L1 cells. DBM effectively inhibited lipid accumulation during adipogenesis, and its inhibitory effect was shown to be due to the down-regulation of adipogenic factors such as CCAAT-enhancer-binding protein-α (C/EBPα), peroxisome proliferator-activated receptor γ (PPARγ), and fatty acid-binding protein 4 (FABP4)...
2018: Biological & Pharmaceutical Bulletin
Jian Sun, Wei Zhuang, Gen Li, Gui Jin, Jia Xu, Ke Ma, Feng Wang, Hua Feng
BACKGROUND: Pulse wave monitoring is widely used to evaluate the physiological and pathological states of the cardiovascular system. OBJECTIVE: High-sensitivity ring sensors were designed, and a simultaneous acquisition platform based on National Instruments T-Clock technology (NI-TCLK) was used to achieve simultaneous pulse detection using both the traditional method and the magnetic induction phase shift (MIPS) method. METHODS: The excitation signal had a frequency of approximately 10...
April 10, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
Alex R Wessel, Brett D Crist, James P Stannard, Gregory J Della Rocca, Aaron M Stoker, Chantelle C Bozynski, Cristi R Cook, Keiichi Kuroki, Carin E Ahner, James L Cook
PURPOSE: Previous studies indicate that Reamer Irrigator Aspirator (RIA) filtrate contains proteins that have the potential to stimulate bone healing. This study aimed to determine the osteoinductive capabilities of RIA filtrate in a validated in vivo model. METHODS: With Institutional Review Board approval, RIA filtrates from 9 patients were collected. The filtrate was processed to remove cells and inorganic particles. A portion of each sample was set aside for protein analysis while the remainder was lyophilized and prepared for implantation...
April 17, 2018: Injury
Jian Wu, Thomas R Mazur, Su Ruan, Chunfeng Lian, Nalini Daniel, Hilary Lashmett, Laura Ochoa, Imran Zoberi, Mark A Anastasio, H Michael Gach, Sasa Mutic, Maria Thomas, Hua Li
Heart motion tracking for radiation therapy treatment planning can result in effective motion management strategies to minimize radiation-induced cardiotoxicity. However, automatic heart motion tracking is challenging due to factors that include the complex spatial relationship between the heart and its neighboring structures, dynamic changes in heart shape, and limited image contrast, resolution, and volume coverage. In this study, we developed and evaluated a deep generative shape model-driven level set method to address these challenges...
April 6, 2018: Medical Image Analysis
Aleksander Kisała, Wojciech Pluskiewicz, Piotr Adamczyk
Functional deterioration due to carpal tunnel syndrome (CTS) may influence the bone status of the forearm and hand. The aim of this prospective study was to establish whether CTS has an impact on bone status at distal parts of the upper limb and to monitor the longitudinal changes of that status during a 1-yr follow-up after surgical treatment. Fifteen women with CTS at mean age of 55.13 ± 9.3 yr, mean weight of 79.18 ± 20.37 kg, and mean height of 157.8 ± 6.17 cm were enrolled into the study...
March 27, 2018: Journal of Clinical Densitometry
Yingqi Chen, Sang-Ho Ye, Hideyoshi Sato, Yang Zhu, Vesselin Shanov, Tarannum Tiasha, Antonio D'Amore, Samuel Luketich, Guojiang Wan, William R Wagner
The challenge of developing scaffolds to reconstruct critical-sized calvarial defects without the addition of high levels of exogenous growth factor remains relevant. Both osteogenic regenerative efficacy as well as suitable mechanical properties for the temporary scaffold system are of importance. In this study, a Mg alloy mesh reinforced polymer/demineralized bone matrix (DBM) hybrid scaffold was designed where the hybrid scaffold was fabricated by a concurrent electrospinning/electrospraying of poly(lactic-co-glycolic) (PLGA) polymer and DBM suspended in hyaluronic acid (HA)...
April 20, 2018: Journal of Tissue Engineering and Regenerative Medicine
Jiajing Zhu, Yongguo Liu, Changhong Yang, Wen Yang, Zhi Chen, Yun Zhang, Shangming Yang, Xindong Wu
Anti-community detection in networks can discover negative relations among objects. However, a few researches pay attention to detecting anti-community structure and they do not consider the node degree and most of them require high computational cost. Block models are promising methods for exploring modular regularities, but their results are highly dependent on the observed structure. In this paper, we first propose a Degree-based Block Model (DBM) for anti-community structure. DBM takes the node degree into consideration and evolves a new objective function Q(C) for evaluation...
2018: PloS One
Wanying Zhang, Peng Chen, Hongfeng Li, Yiquan Zhang, Pengfei Yan, Wenbin Sun
Crystal structures, single-molecule magnetic behavior and ab initio calculations of four new phenoxo-bridged dinuclear dysprosium complexes and their Gd(III) analogues are explored. Complexes [Dy2(DMOMP)2(DBM)4]2*CHCl3 (1), [Dy2(DMOAP)2(DBM)4]2*CHCl3 (2), Dy2(DMOEP)2(DBM)4 (3) and solvent-free Dy2(DMOMP)2(DBM)4 (4) which was obtained by single-crystal to single-crystal transformation from 1 (DMOMP = 1-methyl-3,5-dimethoxy-4-hydroxybenzene, DMOAP = syringaldehyde, DMOEP = methyl syringate) have nearly identical core structure only differing in the substituents at the para position of the phenol moieties of the bridge ligand...
April 17, 2018: Chemistry, An Asian Journal
Szymon Stanczyk, Anna Kafar, Szymon Grzanka, Marcin Sarzynski, Robert Mroczynski, Steve Najda, Tadeusz Suski, Piotr Perlin
In this paper we demonstrate 450 nm (Al,In)GaN graded index separate confinement heterostructure travelling wave optical amplifier with a double 'j-shape' waveguide. The length of the amplifier is 2.5 mm and the width of the ridge is 2.5 µm. The active region consists of three 3.5 nm thick quantum wells. The measured optical gain under CW operation in room temperature exceeded 29 dB for low power input signals. The saturation output power was 21 dBm for 400 mA driving current. The demonstrated amplifier, provides a good solution for the blue light, all nitrides, and master oscillator power amplifier systems...
March 19, 2018: Optics Express
Melanie Newkirk, Fauzia Shakeel, Prabhu Parimi, Pamela Rothpletz-Puglia, Rachael Patusco, Andrea Fleisch Marcus, Rebecca Brody
BACKGROUND: In premature infants, donor breast milk (DBM) is assumed to provide reduced nutrients vs. mother's own milk (MOM). This study examined calorie and protein delivery when very low birth weight infants were fed fortified MOM or DBM, with a known nutrient composition, relative to established nutrition recommendations and to determine if there were differences between the groups. METHODS: A retrospective medical record review was conducted in 29 very low birth weight infants receiving MOM or DBM...
March 30, 2018: Nutrition in Clinical Practice
Ferdinando Da Rin De Lorenzo
Introduction: Non-unions at forearms are usually challenging and difficult to treat. If additionally, an infection is present, reconstructive surgery should be planned only after full debridement, antibiotic treatment, and confirmation, based on clinical observation and laboratory tests that the infection has subsided. Bone grafting may be required for reconstruction. The use of autogenous bone calls for a second surgical site with an increased risk of morbidity. Using bone substitutes may reduce the need for autogenous bone...
November 2017: Journal of Orthopaedic Case Reports
Huarong Huang, Yan He, Lanyue Zhang, Hongping Xiang, Dongli Li, Wenfeng Liu, Xue-Tao Xu, Susan Goodin, Kun Zhang, Xi Zheng
Phenethyl isothiocyanate (PEITC) is a naturally occurring compound found in some cruciferous vegetables. Dibenzoylmethane (DBM) is a minor constituent of licorice. Both compounds have been shown to exert anticancer activities. In the present study, we determined the effects of PEITC and DBM alone or in combination on androgen-independent growth of human prostate cancer cells cultured in vitro and prostate VCaP xenograft tumors in severe combined immunodeficient (SCID) mice. PEITC and DBM in combination had stronger effects on inhibiting the growth and inducing apoptosis than either compound alone in cultured prostate cancer cells...
March 29, 2018: Food & Function
Bernard Dembélé, Charles Sossa Jérôme, Jacques Saizonou, Patrick Charles Makoutodé, Virginie Mongbo Adé, Justine Guedègbé Capo-Chichi, Marius-Edgard Dona Ouendo
INTRODUCTION: To determine the prevalence and determinants of coexistence of maternal overweight or obesity and stunted children (DBM / SCOM) in south-western Benin households. METHODS: This cross-sectional study was carried out in June 2015 on 357 mother-child pairs randomly selected by a two-stage sampling technique in the city of Comè and its surroundings. Data on socio-economic factors, family, health care, dietary quality were collected by questionnaires, observation and documentary review...
January 2018: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
Shuo Lin, Yixin Chen, Yan Bai, Hongjiao Cai, Hui Wei, Houjun Tian, Jianwei Zhao, Yong Chen, Guang Yang, Xiaojun Gu, Kadarkarai Murugan
Tea saponin (TS) is extracted from the seeds of the tea plant and is generally regarded as a safe compound that has insecticidal properties and can act synergistically with other compounds. In this study, the activities of antioxidant enzymes superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and the levels of malondialdehyde (MDA) were compared in midgut tissues of third instar larvae of the diamondback moth (DBM), Plutella xylostella L. (Lepidoptera: Plutellidae). The larvae were fed on three different host plants, cabbage (Brassica oleracea L...
March 20, 2018: Environmental Entomology
Victor O Owino, Carolin Cornelius, Cornelia U Loechl
Multiple drivers of the double burden of malnutrition (DBM) include a rapid shift from predominantly plant-based diets to energy-dense foods based on meats, milk, animal fats and vegetable oils. The shift to overweight and obesity is driven by increased exposure to mass media, urbanization, technological advances in food processing, rising income and increased population density associated with increased access to cheap foods. At the same time, undernutrition persists mainly due to food insecurity and lack of access to safe water, sanitation and adequate health care...
March 23, 2018: Nutrients
John D Koerner, Dessislava Z Markova, Greg D Schroeder, Brian P Calio, Anuj Shah, Corbin W Brooks, Alexander R Vaccaro, D Greg Anderson, Chris K Kepler
BACKGROUND CONTEXT: The systemic response regarding cytokine expression after application of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in a rat spinal fusion model has recently been defined1 , but the local response has not. Defining the local cytokine and growth factor response at the fusion site will help explain the roles of these molecules in the fusion process, as well as that of rhBMP-2. Our hypothesis is that application of rhBMP-2 to the fusion site will alter the local levels of cytokines and growth factors throughout the fusion process, in a manner that is different than the systemic response given the tissue-specific effects of rhBMP-2...
March 14, 2018: Spine Journal: Official Journal of the North American Spine Society
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