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https://www.readbyqxmd.com/read/29905788/extended-use-of-the-wearable-cardioverter-defibrillator-in-patients-at-risk-for-sudden-cardiac-death
#1
Valentina Kutyifa, Katherine Vermilye, Usama A Daimee, Scott McNitt, Helmut Klein, Arthur J Moss
Aims: Data on outcomes in patients using the wearable cardioverter-defibrillator (WCD) > 90 days are limited. We aimed to analyse the clinical course of patients with WCD use ≤90 days vs. WCD use >90 days. Methods and results: We assessed arrhythmia events during WCD use, and ejection fraction (EF) improvement/implantable cardioverter-defibrillator (ICD) implantation at the end of WCD use in patients with WCD use ≤90 days vs. WCD use >90 days enrolled in the WEARIT-II registry, further assessed by disease aetiology (ischaemic vs...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29758638/establishing-the-kinetics-of-ballistic-to-diffusive-transition-using-directional-statistics
#2
Pai Liu, William R Heinson, Benjamin J Sumlin, Kuan-Yu Shen, Rajan K Chakrabarty
We establish the kinetics of ballistic-to-diffusive (BD) transition observed in two-dimensional random walk using directional statistics. Directional correlation is parameterized using the walker's turning angle distribution, which follows the commonly adopted wrapped Cauchy distribution (WCD) function. During the BD transition, the concentration factor (ρ) governing the WCD shape is observed to decrease from its initial value. We next analytically derive the relationship between effective ρ and time, which essentially quantifies the BD transition rate...
April 2018: Physical Review. E
https://www.readbyqxmd.com/read/29749943/experience-with-wearable-cardioverter-defibrillators-at-2-academic-medical-centers
#3
Jordan S Leyton-Mange, William J Hucker, Nino Mihatov, Matthew Reynolds, Christine Albert, Steven A Lubitz, David J Milan
OBJECTIVES: This study sought to characterize the experience in a cohort of patients prescribed a wearable cardioverter-defibrillator (WCD) over a 2-year interval at 2 academic medical centers. BACKGROUND: The WCD is available for patients felt to be at high risk of sudden cardiac death. However, there is a lack of randomized data to guide its use and prescribing patterns vary. METHODS: We retrospectively reviewed indications and therapies of all WCD prescriptions over a 2-year period from 2 large academic medical centers...
February 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29721674/use-of-the-wearable-cardioverter-defibrillator-wcd-and-wcd-based-remote-rhythm-monitoring-in-a-real-life-patient-cohort
#4
Maura M Zylla, Henrike A K Hillmann, Tanja Proctor, Meinhard Kieser, Eberhard Scholz, Edgar Zitron, Hugo A Katus, Dierk Thomas
The wearable cardioverter-defibrillator (WCD) was introduced to provide protection from sudden cardiac death (SCD) in patients with transiently elevated risk or during ongoing risk stratification. Benefits and clinical characteristics of routine WCD use remain to be assessed in larger patient populations. This study aims to identify determinants of WCD compliance, therapies, and inappropriate alarms in a real-life cohort. A total of 106 cases (68.9% male) were included between 11/2010 and 04/2016. WCD therapies, automatically recorded arrhythmia episodes, inappropriate WCD alarms, patient compliance, and outcome after WCD prescription were analyzed...
May 2, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29707164/outcomes-after-asystole-events-occurring-during-wearable-defibrillator-cardioverter-use
#5
Jackson J Liang, Nicole R Bianco, Daniele Muser, Andres Enriquez, Pasquale Santangeli, Benjamin A D'Souza
AIM: To examine whether wearable cardioverter defibrillator (WCD) alarms for asystole improve patient outcomes and survival. METHODS: All asystole episodes recorded by the WCD in 2013 were retrospectively analyzed from a database of device and medical record documentation and customer call reports. Events were classified as asystole episodes if initial presenting arrhythmia was asystole (< 10 beats/minor ≥ 5 s pause). Survival was defined as recovery at the scene or arrival to a medical facility alive, or not requiring immediate medical attention...
April 26, 2018: World Journal of Cardiology
https://www.readbyqxmd.com/read/29678779/experience-with-the-wearable-cardioverter-defibrillator-in-older-patients-results-from-the-prospective-registry-of-patients-using-the-wearable-cardioverter-defibrillator
#6
Usama A Daimee, Katherine Vermilye, Arthur J Moss, Ilan Goldenberg, Helmut U Klein, Scott McNitt, Wojciech Zareba, Valentina Kutyifa
BACKGROUND: Use of the wearable cardioverter-defibrillator (WCD) in older patients has not been described previously. OBJECTIVE: The purpose of this study was to assess WCD wear time, risk of arrhythmic events during WCD use, and implantable cardioverter-defibrillator (ICD) implantation rates after the end of WCD use in patients with age ≥65 years vs <65 years. METHODS: We stratified 1732 patients with ischemic and nonischemic cardiomyopathy from the Prospective Registry of Patients Using the Wearable Defibrillator Registry into 2 subgroups by age: those with age ≥65 years and those with age <65 years...
April 18, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29544442/therapy-optimization-in-patients-with-heart-failure-the-role-of-the-wearable-cardioverter-defibrillator-in-a-real-world-setting
#7
Susanne Röger, Stefanie L Rosenkaimer, Anna Hohneck, Siegfried Lang, Ibrahim El-Battrawy, Boris Rudic, Erol Tülümen, Ksenija Stach, Jürgen Kuschyk, Ibrahim Akin, Martin Borggrefe
BACKGROUND: The wearable cardioverter-defibrillator (WCD) has emerged as a valuable tool to temporarily protect patients at risk for sudden cardiac death (SCD). The aim of this study was to determine the value of the WCD for therapy optimization of heart failure patients. METHODS: One hundred five consecutive patients that received WCD between 4/2012 and 9/2016 were included in the study. All patients were followed for clinical outcome and echocardiographic parameters during WCD therapy and had continued follow-up after WCD therapy, irrespective of subsequent implantable cardioverter-defibrillator (ICD) implantation...
March 15, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29490361/a-pilot-study-to-investigate-the-relationship-between-interaural-differences-in-temporal-bone-anatomy-and-normal-variations-in-caloric-asymmetry
#8
David Carpenter, David Kaylie, Erin Piker, Dennis Frank-Ito
Purpose: This study assesses interaural differences in temporal bone anatomy in subjects with normal caloric findings. Method: Eligible patients included those referred to the Duke University Medical Center otology clinic complaining of dizziness, with a head computed tomography scan and caloric stimulation results within normal ranges (inter-ear difference ≤ 10% or < 25% unilateral weakness). Three-dimensional reconstructions of computed tomography scans in 11 patients were used to calculate the surface area and volume of lateral semicircular canals (LSCCs), mastoid airspaces, mastoid bones, and internal auditory canal diameter and circumference...
March 8, 2018: American Journal of Audiology
https://www.readbyqxmd.com/read/29445060/clinical-usefulness-of-wearable-cardioverter-defibrillator-wcd-and-current-understanding-of-its-clinical-indication-in-japan
#9
Shinichi Niwano, Yukio Sekiguchi, Yosuke Ishii, Yuki Iwasaki, Ritsushi Kato, Hideo Okamura, Masahiko Takagi, Takashi Kurita, Takashi Nitta
Prevention of sudden cardiac death (SCD) has become an important issue in today's cardiovascular field, together with various developments in secondary prevention of basic cardiac diseases. The importance of the implantable cardioverter defibrillator (ICD) is now widely accepted because it has exhibited significant improvement in patients' prognoses in ischemic and non-ischemic cardiovascular diseases. However, there is an unignorable gap between the ICD indication in the guidelines and real-world high-risk patients for SCD, especially in the acute recovery phase of cardiac injury...
February 14, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29277221/wearable-cardioverter-defibrillator-the-lifevest-device-design-limitations-and-areas-of-improvement
#10
Manyoo Agarwal, Dennis Narcisse, Nader Khouzam, Rami N Khouzam
Sudden cardiac death is a potentially fatal clinical event demanding use of emergent intervention such as defibrillation. Over the last 1 decade, development of devices such as implantable and wearable cardioverter defibrillators (WCD) has provided new avenues in the management of sudden cardiac death. Several clinical studies have commented on the therapeutic and preventive aspect of WCD, however, literature describing the device functioning and limitations is limited. In this review study, we describe the technical aspects and limitations of WCD with a focus on identifying potential areas of improvement and framework for future research studies...
February 2018: Current Problems in Cardiology
https://www.readbyqxmd.com/read/29234842/-patients-with-a-wearable-cardioverter-defibrillator-wcd-prescription-function-and-rehabilitation-support
#11
REVIEW
A Schlitt, M Guha, M Noutsias, H H Klein, H U Klein
Assessment of a permanent risk of life-threatening ventricular arrhythmia in patients with severely reduced left ventricular ejection fraction (LVEF <35%), e. g. after myocarditis, dilated cardiomyopathy, acute myocardial infarction, in patients with postpartum cardiomyopathy or implantable cardioverter-defibrillator (ICD) and cardiac resynchronization treatment plus defibrillator (CRT-D) infection with temporary explantation of the system is a medical challenge. This is time-consuming and unsafe because life-threatening ventricular arrhythmias may occur during the time of risk assessment...
December 12, 2017: Herz
https://www.readbyqxmd.com/read/29180909/wearable-cardioverter-defibrillators-for-the-prevention-of-sudden-cardiac-arrest-a-health-technology-assessment-and-patient-focus-group-study
#12
Sabine Ettinger, Michal Stanak, Piotr Szymański, Claudia Wild, Romana Tandara Haček, Darija Erčević, Renata Grenković, Mirjana Huić
Aim: To summarize the evidence on clinical effectiveness and safety of wearable cardioverter defibrillator (WCD) therapy for primary and secondary prevention of sudden cardiac arrest in patients at risk. Methods: We performed a systematic literature search in databases including MEDLINE via OVID, Embase, the Cochrane Library, and CRD (DARE, NHS-EED, HTA). The evidence obtained was summarized according to GRADE methodology. A health technology assessment (HTA) was conducted using the HTA Core Model® for rapid relative effectiveness assessment...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/29178898/the-wearable-cardioverter-defibrillator-as-a-bridge-to-reimplantation-in-patients-with-icd-or-crt-d-related-infections
#13
L Castro, S Pecha, M Linder, J Vogler, N Gosau, C Meyer, S Willems, H Reichenspurner, S Hakmi
BACKGROUND: The approach to treat device infection in patients with implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) is a challenging procedure. Optimal treatment is complete extraction of the infected device. To protect these patients from sudden cardiac arrest while waiting for reimplantation and to avoid recurrent infection, a wearable cardioverter defibrillator (WCD) seems to be a valuable solution. Therefore, we investigated the management and outcome of patients with ICD or CRT-D infections using the WCD as a bridge to re-implantation after lead extraction procedures...
November 25, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29155999/high-incomplete-skeletal-muscle-fatty-acid-oxidation-explains-low-muscle-insulin-sensitivity-in-poorly-controlled-t2d
#14
Timothy P Gavin, Jacob M Ernst, Hyo-Bum Kwak, Sarah E Caudill, Melissa A Reed, Ron T Garner, Yaohui Nie, Jessica A Weiss, Walter J Pories, Moahad Dar, Chien-Te Lin, Monica J Hubal, P Darrell Neufer, Shihuan Kuang, G Lynis Dohm
Context: Almost 50% of type 2 diabetic (T2D) patients are poorly controlled [glycated hemoglobin (HbA1c) ≥ 7%]; however, the mechanisms responsible for progressively worsening glycemic control are poorly understood. Lower skeletal muscle mitochondrial respiratory capacity is associated with low insulin sensitivity and the development of T2D. Objective: We investigated if skeletal muscle insulin sensitivity (SI) was different between well-controlled T2D (WCD) and poorly controlled T2D (PCD) and if the difference was associated with differences resulting from mitochondrial respiratory function...
March 1, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29153771/outcome-of-patients-with-in-hospital-ventricular-tachycardia-and-ventricular-fibrillation-arrest-while-using-a-wearable-cardioverter-defibrillator
#15
Kenneth A Ellenbogen, Chingping Wan, David M Shavelle
In-hospital sudden cardiac arrests occurring during nighttime and weekend hours or within unmonitored hospital areas have been reported to have a poorer outcomes than monitored cardiac arrest. This study sought to assess the outcome of in-hospital ventricular tachycardia (VT) and ventricular fibrillation (VF) arrest by time of day, day of week, and within-hospital location when using a wearable cardioverter defibrillator (WCD). We retrospectively identified and reviewed consecutive in-hospital VT/VF arrests from January 2011 to May 2015 experienced by patients wearing a WCD using the manufacturer's postmarket registry...
January 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29124430/oversensing-of-the-wearable-cardioverter-defibrillator-during-bipolar-ventricular-stimulation
#16
Martin Manninger, Tanja Odeneg, Friedrich Fruhwald, Helmut Brussee, Daniel Scherr
The wearable cardioverter defibrillator (WCD) is a temporary treatment option for patients with potentially reversible risk of sudden cardiac death. This case demonstrates a pitfall during WCD usage in a pacemaker-dependent patient as well as a possible solution allowing continuation of WCD therapy. Bipolar stimulation may lead to double counting of the WCD detection algorithm resulting in false alarm or inappropriate therapy.
December 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29072998/real-world-utilization-and-impact-of-the-wearable-cardioverter-defibrillator-in-a-community-setting
#17
Aditi Naniwadekar, Talal Alnabelsi, Kamal Joshi, Edinrin Obasare, Allan Greenspan, Sumeet Mainigi
INTRODUCTION: The wearable cardioverter-defibrillator (WCD) is used in patients at risk for sudden cardiac death (SCD) but not immediate candidates for intracardiac defibrillator (ICD) implantation. METHODS: We performed a single center retrospective study of patients prescribed WCD upon hospital discharge from January 2002 to October 2015. Clinical characteristics were obtained from the hospital electronic database and device data from Zoll LifeVest database. RESULTS: Of 140 patients, 62% were men, 85...
May 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29064577/wearable-cardioverter-defibrillators-in-schools-a-guide-for-parents-and-educators
#18
Ashley E Burch, David S Spar, Samuel F Sears
Keeping children safe is a goal for everyone. To stay safe, some children need a wearable cardioverter defibrillator (WCD). WCDs protect individuals who are at risk for life-threatening arrhythmias. The LifeVest® (ZOLL, Pittsburgh, PA, USA) is a WCD that identifies, records, and treats potentially life-threatening abnormal heartbeats, or arrhythmias. The WCD will provide electrical energy to the heart with up to five high-energy shocks if a potentially dangerous cardiac arrhythmia is detected. This type of arrhythmia, if not treated within a short time period (less than 2 minutes), can result in disruption of blood flow to the brain and other vital organs (that is, a sudden cardiac arrest), and death can occur within minutes...
December 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28993851/usefulness-of-the-wcd-in-patients-with-suspected-tachymyopathy
#19
Julia W Erath, Mate Vamos, Alexander P Benz, Stefan H Hohnloser
AIMS: The wearable cardioverter defibrillator (WCD) is used for temporary protection of patients deemed to be at high risk for sudden death. There is limited experience regarding the clinical development of patients with tachymyopathy. We aimed to evaluate the clinical development of tachymyopathy patients protected with a WCD in a single-center non-randomized patient cohort. METHODS AND RESULTS: We fitted 130 consecutive patients deemed to be at high risk for ventricular tachyarrhythmias with the WCD...
January 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28969980/ventricular-arrhythmia-occurrence-and-compliance-in-patients-treated-with-the-wearable-cardioverter-defibrillator-following-percutaneous-coronary-intervention
#20
Jérémie Barraud, Pauline Pinon, Marc Laine, Jennifer Cautela, Morgane Orabona, Linda Koutbi, Johan Pinto, Franck Thuny, Frederic Franceschi, Franck Paganelli, Laurent Bonello, Michaël Peyrol
BACKGROUND: The wearable cardioverter defibrillator (WCD) is a life-saving therapy in patients with high risk of arrhythmic death. We aimed to evaluate ventricular arrhythmia (VA) occurrence rate and compliance with the WCD during the first 90 days following myocardial revascularisation with percutaneous coronary intervention (PCI) in patients with left ventricular ejection fraction (LVEF) <30%. METHODS: From September 2015 to November 2016, clinical characteristics, WCD recordings and compliance data of the aforementioned subset of patients were prospectively collected...
September 25, 2017: Heart, Lung & Circulation
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